CN103520649A - Traditional Chinese medicine for treating facial neuritis - Google Patents

Traditional Chinese medicine for treating facial neuritis Download PDF

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CN103520649A
CN103520649A CN201310499629.0A CN201310499629A CN103520649A CN 103520649 A CN103520649 A CN 103520649A CN 201310499629 A CN201310499629 A CN 201310499629A CN 103520649 A CN103520649 A CN 103520649A
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chinese medicine
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facial neuritis
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fine powder
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CN103520649B (en
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杜霞
于辉
李丽洁
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Abstract

The invention relates to the field of Chinese traditional medicine formulas and in particular relates to a traditional Chinese medicine for treating facial neuritis. The traditional Chinese medicine is characterized by consisting of the following raw materials in percentage by weight: 9%-13% of concha haliotidis, 7%-10% of semen cassia, 12%-15% of nacre mother of pearl, 3%-5% of long-noded pit viper, 7%-10% of lonicerae flos, 1%-2% of leech, 2%-4% of periostracum cicada, 0.2%-1% of Chinese blister beetle, 4%-6% of pangolin, 2%-3% of castor bean, 7%-9% of antler, 2%-3% of cinnamon, 1%-2% of asarum, 4%-6% of cortex dictamni, 5%-8% of the root bark of white mulberry, 4%-6% of radix zanthoxyli, 5%-7% of root of common peony, and 4%-6% of turmeric. A preparation method of the traditional Chinese medicine comprises the following steps: drying the long-noded pit viper, the leech and the periostracum cicada, grinding into fine powder for future use, adding water into the rest 15 raw materials, soaking, then decocting, removing residues to obtain a filtered solution, and adding the fine powder into the filtered solution. The traditional Chinese medicine for treating facial neuritis is low in cost and high in treatment effect of facial neuritis, has no toxic and side effect, has functions of clearing heat, removing toxicity, strengthening body resistance, eliminating evil, activating blood, dissolving stasis, dispelling wind, removing obstruction in the meridians, tonifying qi, calming the nerves and balancing Yin-Yang, and has a curative effect on facial neuritis in an acute phase and a recovery phase.

Description

The Chinese medicine for the treatment of facial neuritis
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine that is used for the treatment of facial neuritis.
Background technology
As everyone knows, facial neuritis also claims facial paralysis, is because of peripheral facial paralysis due to nervus facialis nonspecific inflammation in stylomastoid foramen.Nervus facialis ischemia, edema because can only holding nervus facialis, pass through bone facial pipe, so once must cause nerve compression.Viral infection, autonomic nervous function shakiness etc. all can cause local nerve nutrient vessel spasm, neural ischemia, edema to occur facial muscle paralysis.Facial neuritis early stage pathology changes and to be mainly neural edema and demyelination, and axonal degeneration can appear in severe patient, and particularly remarkable with inner minute of stylomastoid foramen and facial canal, any age all can fall ill, and is more common in 20-40 year, and male is more than women.Common Acute onset, facial paralysis reaches peak in a few hours to a couple of days.Rest pain and mastoidea tenderness after 1-2 day ill picking up the ears before some patients were paralysis.Main manifestations is the myoparalysis of patient's facial expression, and volume stricture of vagina disappears, and can not frown by wrinkle volume, and palpebral fissure can not closure or dysraphism.While closing one's eyes, double eyeball outwards rotates top, exposes white sclera, and nasolabial fold shoals, ptosis of labial angle, and in the time of grinningly, bicker is askew to strong side.Due to orbicularis oris paralysis, air-blowing, the gas leakage of whistling; Buccinator muscle paralysis, food is easily detained disease side gums.Can there are two sense of taste disappearances of first three minute of homonymy tongue in nervus facialis pathological changes as above in tympanic cord, occur that stapedial nerve is impaired with upper part, there are tongue two sense of taste disappearance and the hyperacusises of first three minute simultaneously, and can or feel to go down with position pain such as mastoidea, auricle, external auditory meatuss.The traditional Chinese medical science claims " facial paralysis " " facial paralysis " " wapperijaw wind " " facial hemiparalysis " etc.Current clinical doctor trained in Western medicine mainly adopts the Drug therapys such as corticosteroid, vitamin B group and antiviral, and not only effect is not good enough, easily recurrence, and leave the strange sequela such as stiff of facial hemiparalysis, slobbering, facial expression, patient is felt oneself inferior.
Summary of the invention
Technical problem to be solved by this invention is in order to overcome above-mentioned the deficiencies in the prior art, a kind of Chinese medicine for the treatment of facial neuritis is provided, cost is low, treatment facial neuritis curative effect is high, have no side effect, there is heat-clearing and toxic substances removing, strengthening vital QI to eliminate pathogenic factors, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral, invigorating QI and tranquilization, Yin Yang balancing effect, to acute stage, convalescent period facial neuritis all effective.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine for the treatment of facial neuritis, it is characterized in that raw material composition is by weight percentage: Concha Haliotidis 9-13%, Semen Cassiae 7-10%, Concha Margaritifera 12-15%, Agkistrodon 3-5%, Flos Lonicerae 7-10%, Hirudo 1-2%, Periostracum Cicadae 2-4%, Mylabris 0.2-1%, Squama Manis 4-6%, Semen Ricini 2-3%, Cornu Cervi 7-9%, Cortex Cinnamomi 2-3%, Herba Asari 1-2%, Cortex Dictamni 4-6%, Cortex Mori 5-8%, Radix Zanthoxyli 4-6%, Radix Paeoniae Rubra 5-7%, Rhizoma Curcumae Longae 4-6%, by Agkistrodon, Hirudo, Periostracum Cicadae three taste crude drug are dried, grind that to be ground into fine powder standby, 15 remaining taste raw materials are soaked, then decoct the filtrate of removing slag to obtain, above-mentioned fine powder is joined in filtrate.
The invention has the beneficial effects as follows, cost is low, and treatment facial neuritis curative effect is high, has no side effect, and does not recur and leaves over sequela, has heat-clearing and toxic substances removing, strengthening vital QI to eliminate pathogenic factors, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral, invigorating QI and tranquilization, Yin Yang balancing effect.By improving facial paralysis patient local blood circulation, inflammation and the edema of eliminating nervus facialis, restored balance oppressed face nerve, impels the mechanism of qi at facial paralysis position unimpeded, improve the nutrition and the metabolism thereof that relate to facial paralysis muscle group, repair the structure of relay cell, recover its function, promote germinateing again of synapse, axon regeneration extends, re-establish Nervous pathway, and then recover the neural domination to facial muscle group, to acute stage, convalescent period facial neuritis all effective.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described:
Embodiment mono-:
Adopting Concha Haliotidis, Semen Cassiae, Concha Margaritifera, Agkistrodon, Flos Lonicerae, Hirudo, Periostracum Cicadae, Mylabris, Squama Manis, Semen Ricini, Cornu Cervi, Cortex Cinnamomi, Herba Asari, Cortex Dictamni, Cortex Mori, Radix Zanthoxyli, Radix Paeoniae Rubra, Rhizoma Curcumae Longae is that raw material is prepared from.Every pair of its component (% by weight) is Semen Cassiae 11.2, Semen Cassiae 8.9, Concha Margaritifera 14.1, Agkistrodon 4.7, Flos Lonicerae 8.9, Hirudo 1.5, Periostracum Cicadae 3.1, Mylabris 0.4, Squama Manis 5.1, Semen Ricini 2.6, Cornu Cervi 7.7, Cortex Cinnamomi 2.5, Herba Asari 1.2, Cortex Dictamni 4.8, Cortex Mori 5.9, Radix Zanthoxyli 5.5, Radix Paeoniae Rubra 6.6, Rhizoma Curcumae Longae 5.3.Get 185 grams of above-mentioned 18 taste Chinese herbal medicine gross weights, first Agkistrodon, Hirudo, Periostracum Cicadae three tastes are dried, grind and be ground into fine powder, cross 120 mesh sieves, bottle standby and carry out labelling.Again respectively by Concha Haliotidis, Concha Margaritifera, Squama Manis, Cornu Cervi four taste Chinese herbal medicine add 800 milliliters, water, soak 2 hours, 30-40 minute is decocted first, the 11 taste Chinese herbal medicine of Yuing add water 900-1000 milliliter, soak about 2 hours 30-40 minute, pour into together in the four taste Chinese herbal medicine that are decocted first, intense fire boils, slow fire decocts to 80-90 minute, the 250 milliliters of left and right of filtrate of removing slag to obtain, medicinal residues add 300 milliliters of left and right of water again, decoct 30-40 minute, remove slag to obtain 100 milliliters of filtrates, be total to obtain 350 milliliters of left and right medicine juice, again oven dry is ground and is ground into fine powder, carrying out the standby thin medicated powder of the three tastes end of labelling pours in medicine juice, stir, pack in aseptic vial, seal bottle cap is standby.1 dose minute every day 2 times is oral, each 175 milliliters of left and right of decoction being taken warmly on an empty stomach.In the time of the Chinese medicinal decoction of oral medication facial neuritis, then 20 grams of fit applications Bombyx Batryticatus, 20 grams of Scorpios, 4 of Scolopendras, 20 grams of the Radixs Angelicae Dahuricae, 20 grams of oven dry of Ramulus Uncariae Cum Uncis, grind and are ground into fine powder, cross 100 mesh sieves, bottle standby.The powder 4-5 gram that gets it filled every night puts into kidney basin, then mashes extracting juice with 10 grams of fresh gingers, with Sucus Zingberis, by the loose shape of medicated powder furnishing, is spread in diameter 3cm SHANGSHI ZHITONG GAO, is affixed on cave, Ipsilateral ShiShimonoseki, and (first find accurately acupuncture point rub again paste), take off inferior morning.Oral jewel begs silver-colored soup to coordinate medicated powder to apply cave, Ipsilateral ShiShimonoseki every day 1 time, and 10 days is a course for the treatment of, has a rest and carries out next course for the treatment of for 2 days again, generally applies 3 courses for the treatment of.
Principal agent Concha Haliotidis chemical composition master of the present invention is containing calcium carbonate, still containing Choline, conchiolin etc.Nature and flavor are salty, cold, return Liver Channel.There is suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving effect,, conjunctival congestion cataracta dizzy for having a headache, blurring of vision, optic atrohic blindness nyctalopia.Semen Cassiae infusion reduces blood pressure and diuresis to anesthetized animal, containing anthraquinones, has cathartic, shrinks uterus effect.Bacteriostatic experiment has inhibitory action to staphylococcus, diphtheria corynebacterium, Bacillus megatherium, Bacillus typhi, Salmonella paratyphi etc., and multiple pathogenic dermatophytes is had to inhibitory action.Nature and flavor are sweet, bitter, salty, be slightly cold, and return liver, large intestine channel.Have clearing away heat to improve acuity of vision, effect of relaxing bowel, for the puckery pain of conjunctival congestion, the many tear of photophobia, dizzy, the poor vision of having a headache, constipation.Concha Margaritifera chemical composition contains calcium carbonate etc., and nature and flavor are salty, cold, return liver, heart channel.There is suppressing the hyperactive liver and subsiding YANG, the arresting convulsion of calming the nerves, improving acuity of vision and removing nebula effect,, palpitation with fear insomnia dizzy for having a headache, conjunctival congestion cataracta, blurring of vision.Agkistrodon has hypotensive effect, is mainly direct blood vessel dilating and causes, but the effect of maincenter and other aspects is also had to certain relation, therefore think comprehensive effect.Nature and flavor are sweet, salty, warm, poisonous, return Liver Channel.Have dispel the wind, dredging collateral, relieving convulsion effect, for rheumatoid arthritis stubborn, numbness contracture, air port eye
Figure BSA0000096554010000031
tiltedly, hemiplegia, tic spasm, tetanus, leprosy, scabies.Flos Lonicerae nature and flavor are sweet, tremble with fear, return lung, the heart, stomach warp.There is heat-clearing and toxic substances removing, dispelling wind and heat pathogens effect, for carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease.Hirudo nature and flavor are salty, bitter, flat, slightly poisonous, return Liver Channel.Have that removing blood stasis stimulates the menstrual flow, Zhu Yu Xiao Disorder effect, for blood stasis amenorrhea, mass in the abdomen mass in the abdomen, apoplectic hemiplegia, injury from falling down.Periostracum Cicadae nature and flavor are sweet, tremble with fear, return lung, Liver Channel, have dispelling wind and heat pathogens, sore-throat relieving, rash, improving acuity of vision and removing nebula, spasmolytic effect, for anemopyretic cold, pharyngalgia hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, tetanus.Mylabris nature and flavor are pungent, hot, very toxic, return liver, stomach, kidney channel.There is removing blood stasis, dispersing accumulated pathogens to resolve the mass, counteracting toxic substances phagedenoma effect, Yong Yu mass in the abdomen, amenorrhea, stubborn dermatitis etc.Squama Manis nature and flavor are salty, be slightly cold, return liver, stomach warp.There is the Xiao of invigorating blood circulation Disorder, the stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral effect.For amenorrhea and mass in the abdomen, galactostasis, carbuncle sore tumefacting virus, rheumatic arthralgia, paralysis due to windstroke, numbness contracture.Semen Ricini nature and flavor are sweet, pungent, flat, poisonous, return large intestine, lung meridian.Have and rush down lower logical stagnant, detumescence and drawing out poison effect.For constipation due to dry stool, swollen ulcer drug, sore throat, scrofula, scrofula.Cornu Cervi nature and flavor are salty, wet, return kidney, Liver Channel.There is the kidney warming sun, bone and muscle strengthening, promoting the circulation of blood detumescence effect.For insufficiency of kidney-YANG, impotence and seminal emission, spinal column cold type of pain, carbuncle of yin nature skin infection, acute mastitis from the beginning of, swelling and pain due to blood stasis.Cortex Cinnamomi nature and flavor are pungent, sweet, hot greatly.Return kidney, spleen, conscience warp.There is supporing yang, the guiding fire to origin of the fire of benefit, dispersing cold for relieving pain, temperature three-way meridian effect.For sexual impotence cold womb, chills and pain of the waist and kness, suffer from a deficiency of the kidney breathe heavily, upward floating of YANG in deficiency condition, dizzy conjunctival congestion, trusted subordinate's cold type of pain, deficiency and coldness are vomited and diarrhoea, colic of cold type is suffered from abdominal pain, dysmenorrhea amenorrhea.Herba Asari nature and flavor are pungent, warm, GUIXIN, lung, kidney channel.There is expelling wind and cold, wind-expelling pain-stopping, sensible, warming the lung to resolve fluid-retention effect.For anemofrigid cold, headache, toothache, nasal obstruction watery nasal discharge, allergic rhinitis, nasal sinusitis, rheumatic arthralgia, phlegm retention, breath with cough.Cortex Dictamni taste is bitter, tremble with fear, return spleen, stomach, urinary bladder channel.There is heat clearing and damp drying, detoxicating functions dispels the wind., eczema dripping for damp and hot sore, yellow fluid, rheumatism pyretic arthralgia etc.Cortex Mori nature and flavor are sweet, tremble with fear, return lung meridian.There is eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema effect, for dyspnea and cough due to lung-heat, edema distension oliguria, appearance skin edema.Radix Zanthoxyli nature and flavor are bitter, pungent, flat, slightly poisonous, return liver, stomach warp.There is blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, dispelling wind and removing obstruction in the collateral, removing toxic substances and promoting subsidence of swelling effect.For injury from falling down, stomachache, toothache, rheumatic arthralgia, venom etc.Radix Paeoniae Rubra nature and flavor are bitter, be slightly cold, return Liver Channel.There is clearing away heat and cooling blood, eliminating stasis to stop pain effect.For heat, enter nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, mass in the abdomen stomachache, carbuncle skin infection etc.Rhizoma Curcumae Longae nature and flavor acrid, bitter, warm, return spleen, Liver Channel.There is removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia effect.For the twinge of the breast side of body, obstruction of qi in the chest and cardialgia, dysmenorrhea amenorrhea, rheumatism shoulder arm pain etc.The ingenious prescription of 18 taste Chinese herbal medicine, science compatibility, mutual reinforcement between between medicine, mutual-assistance compatibility.Synergism can be played, curative effect of medication can be improved; Mutual restraint between two drugs, mutual-detoxication compatibility, can alleviate or eliminate poisonous side effect of medicine.Mutual coordinative role between medicine, to improve local blood circulation, eliminates inflammation and the edema of nervus facialis, promotes neurological functional recovery, reaches the object of healing.
The embodiment that each raw material of the present invention also can the listed ratio of according to the form below (percentage by weight) mixes realizes, and its processing technique is identical with embodiment 1.
The present invention is described in further detail in the clinical experiment of carrying out below in conjunction with Wendeng City, Wo Yuan,Ji In Shandong Weihai central hospital:
1, case selection: selected case Wei Wo institute Neurology Department is from 73 routine patients of in February, 2009 to 2013 year diagnosis and treatment in July, male 41 examples, female's 32 examples, age 25-67 year; The course of disease 9 hours to 5 days, the longest 1 example 30 days; One-sided ill 69 examples, ill 4 examples of bilateral.
2, diagnostic criteria: according to State Administration of Traditional Chinese Medicine, traditional Chinese medical science disease Standardization of diagnosis and curative effect: Acute onset, the myoparalysis of patient's facial expression, volume stricture of vagina disappears, palpebral fissure can not closure or dysraphism, and bicker is askew to strong side, and Ipsilateral nasolabial fold shoals, buccinator muscle paralysis, food is easily detained disease side gums etc.
3, Therapeutic Method: 1 dose minute every day 2 times is oral, each 175 milliliters of left and right of decoction being taken warmly on an empty stomach.In the time of the Chinese medicinal decoction of oral medication facial neuritis, then 20 grams of fit applications Bombyx Batryticatus, 20 grams of Scorpios, 4 of Scolopendras, 20 grams of the Radixs Angelicae Dahuricae, 20 grams of oven dry of Ramulus Uncariae Cum Uncis, grind and be ground into fine powder, cross 100 mesh sieves, bottle standby.The powder 4-5 gram that gets it filled every night puts into kidney basin, then mashes extracting juice with 10 grams of fresh gingers, with Sucus Zingberis, by the loose shape of medicated powder furnishing, is spread in diameter 3cm SHANGSHI ZHITONG GAO, is affixed on cave, Ipsilateral ShiShimonoseki (first find acupuncture point accurately and rub, then paste), and take off inferior morning.Oral jewel begs silver-colored soup to coordinate medicated powder to apply cave, Ipsilateral ShiShimonoseki once a day, and 10 days is a course for the treatment of, has a rest and carries out next course for the treatment of for 2 days again, applies 3 courses for the treatment of.
4, curative effect judging standard: I level is normal 100 minutes; II level is that slight dysfunction is more than 75 minutes; III level is moderate dysfunction (75-50 divides); IV level is compared with severe dysfunction (50 minutes following).Healing, effective, transfers well total effective rate to.
Cure: reach I level: bilateral volume stricture of vagina, nasolabial fold recover symmetrical, frown and close one's eyes normal, during the drum cheek bicker air tight, during feed, between tooth cheek, be not detained food debris, when speaking and laughing at bicker not crooked, facial expression is normal, scoring full marks.
Effective: to reach II level: bilateral volume stricture of vagina and nasolabial fold almost symmetry, eye is closed not good enough, frowns and shows slightly unable, while frowning, volume stricture of vagina is shallow than strong side, during the bulging cheek bicker air tight, during feed, between tooth cheek, be not detained food debris, while laughing at, visible bicker is slightly asymmetric.
Take a turn for the better: facial neuritis clinical manifestation reverts to III level, scoring is between 75-50 divides.
Invalid: after treating 3 courses for the treatment of, its clinical manifestation is without obvious recovery, or is slightly improved, scoring is below 50 minutes.
5, therapeutic effect: use the routine patient of the present invention 73, after treating 3 courses for the treatment of, application the standard of curative effect evaluation carries out treatment effectiveness evaluation: cure 38 examples, more account for 52%; Effective 23 examples, account for 32%; 7 examples that take a turn for the better, account for 9%; Invalid 5 examples, account for 7%.Total effective rate is 93%.

Claims (1)

1. a Chinese medicine for the treatment of facial neuritis, it is characterized in that: raw material composition is by weight percentage, Concha Haliotidis 9-13%, Semen Cassiae 7-10%, Concha Margaritifera 12-15%, Agkistrodon 3-5%, Flos Lonicerae 7-10%, Hirudo 1-2%, Periostracum Cicadae 2-4%, Mylabris 0.2-1%, Squama Manis 4-6%, Semen Ricini 2-3%, Cornu Cervi 7-9%, Cortex Cinnamomi 2-3%, Herba Asari 1-2%, Cortex Dictamni 4-6%, Cortex Mori 5-8%, Radix Zanthoxyli 4-6%, Radix Paeoniae Rubra 5-7%, Rhizoma Curcumae Longae 4-6%, by Agkistrodon, Hirudo, Periostracum Cicadae three taste crude drug are dried, grind that to be ground into fine powder standby, 15 remaining taste raw materials are soaked, then decoct the filtrate of removing slag to obtain, above-mentioned fine powder is joined in filtrate.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103920123A (en) * 2014-04-29 2014-07-16 高本梅 Traditional Chinese medicine for treating facial neuritis and preparation method thereof
CN105193964A (en) * 2014-06-25 2015-12-30 封海山 External application plaster
CN105250597A (en) * 2015-11-20 2016-01-20 潘剑崎 Traditional Chinese medicine for treating peripheral facial paralysis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101461879A (en) * 2008-05-16 2009-06-24 胡元广 Plaster for treating neck, spine, protrusion of lumbar vertebral disc, hyperosteogeny, arthralgia and myalgia
CN101744906A (en) * 2008-12-01 2010-06-23 河北以岭医药研究院有限公司 Applications of Chinese medicinal composition to preparation of medicament for treating facial paralysis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101461879A (en) * 2008-05-16 2009-06-24 胡元广 Plaster for treating neck, spine, protrusion of lumbar vertebral disc, hyperosteogeny, arthralgia and myalgia
CN101744906A (en) * 2008-12-01 2010-06-23 河北以岭医药研究院有限公司 Applications of Chinese medicinal composition to preparation of medicament for treating facial paralysis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103920123A (en) * 2014-04-29 2014-07-16 高本梅 Traditional Chinese medicine for treating facial neuritis and preparation method thereof
CN105193964A (en) * 2014-06-25 2015-12-30 封海山 External application plaster
CN105250597A (en) * 2015-11-20 2016-01-20 潘剑崎 Traditional Chinese medicine for treating peripheral facial paralysis

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