CN105213809A - A kind ofly treat the Chinese medicine oral liquid and preparation method that persistence low grade fever do not move back - Google Patents
A kind ofly treat the Chinese medicine oral liquid and preparation method that persistence low grade fever do not move back Download PDFInfo
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Abstract
The present invention discloses and a kind ofly treats the Chinese medicine oral liquid and preparation method that persistence low grade fever do not move back, and is made up of following raw material: Radix Astragali 28-32 part, Radix Pseudostellariae 18-22 part, Rhizoma Polygonati Odorati 18-22 part, Radix Ophiopogonis 18-22 part, Cortex Moutan 13-17 part, Rhizoma Dioscoreae 18-32 part, Herba Dendrobii 18-22 part, Radix Cynanchi Atrati 13-17 part, Fructus Viticis 10-14 part, Radix Glehniae 28-32 part, Radix Stellariae 13-17 part, Radix Saposhnikoviae 8-12 part, Cortex Phellodendri 13-17 part, Stamen Nelumbinis 10-14 part, Rhizoma Anemarrhenae 13-17 part, Radix Glycyrrhizae 4-8 part.The present invention has heat clearing and damp drying, eliminating fire and detoxication, brings down a fever except the effect of steaming, and be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid for the treatment of persistence low grade fever and not moving back, belong to the field of Chinese medicines.
Background technology
Persistent fever is mainly divided into germ infective fever with noninfectious fever, simultaneously, the time of this condition of illness heating is long, the state of an illness such as fever can be caused, need to note nursing especially, Etiological causes the cause of disease of heating a lot, roughly can divide into infectious and non-infectious two kinds, and be common with infective fever, infective fever is owing to having infected antibacterial, virus, fungus, parasites etc. cause, and noninfectious fever reason is a lot, after being found in major operation, internal hemorrhage, large hematoma, large-area burns, tumor, rheumatism, hyperthyroidism etc., the western medical treatment Main Means taked this disease at present takes antibiotic, but western medicine is temporary transient symptom management mostly, and it is harmful unhelpful to take too many antibiotic, because abuse of antibiotics may cause bottleneck throat normal flora to be lacked of proper care, and resistance can be caused to strengthen, immune function of human body goes down, cause Relapse rate difficulty more.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine oral liquid for the treatment of persistence low grade fever and not moving back, it has heat clearing and damp drying, eliminating fire and detoxication, brings down a fever except the effect of steaming.
The present invention is achieved through the following technical solutions:
Treat the Chinese medicine oral liquid that persistence low grade fever does not move back, be made up of following raw material: Radix Astragali 28-32 part, Radix Pseudostellariae 18-22 part, Rhizoma Polygonati Odorati 18-22 part, Radix Ophiopogonis 18-22 part, Cortex Moutan 13-17 part, Rhizoma Dioscoreae 18-32 part, Herba Dendrobii 18-22 part, Radix Cynanchi Atrati 13-17 part, Fructus Viticis 10-14 part, Radix Glehniae 28-32 part, Radix Stellariae 13-17 part, Radix Saposhnikoviae 8-12 part, Cortex Phellodendri 13-17 part, Stamen Nelumbinis 10-14 part, Rhizoma Anemarrhenae 13-17 part, Radix Glycyrrhizae 4-8 part.
Preferably, each parts by weight of raw materials is: the Radix Astragali 30 parts, Radix Pseudostellariae 20 parts, Rhizoma Polygonati Odorati 20 parts, Radix Ophiopogonis 20 parts, Cortex Moutan 15 parts, Rhizoma Dioscoreae 30 parts, Herba Dendrobii 20 parts, Radix Cynanchi Atrati 15 parts, Fructus Viticis 12 parts, Radix Glehniae 30 parts, Radix Stellariae 15 parts, Radix Saposhnikoviae 10 parts, Cortex Phellodendri 15 parts, Stamen Nelumbinis 12 parts, the Rhizoma Anemarrhenae 15 parts, 6 parts, Radix Glycyrrhizae.
Pharmacological action:
The Radix Astragali: nature and flavor with return through: sweet, temperature; Return lung, spleen channel, function with cure mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation; Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Radix Pseudostellariae: nature and flavor with return through sweet, micro-hardship, flat; Return spleen, lung meridian, function with cure mainly: replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung; Tired for insufficiency of the spleen body, inappetence, weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough.
Rhizoma Polygonati Odorati: nature and flavor with return through: sweet, be slightly cold; Attach to the lung and stomach meridians, function with cure mainly: nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst; For lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.
Radix Ophiopogonis: nature and flavor with return through: sweet, micro-hardship, is slightly cold; GUIXIN, lung, stomach warp, function with cure mainly: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire; For dryness of the lung dry cough; Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
Cortex Moutan: nature and flavor with return through: bitter, pungent, be slightly cold; GUIXIN, liver, kidney channel, function with cure mainly: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling; For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Rhizoma Dioscoreae: nature and flavor with return through: sweet, flat; Return spleen, lung, kidney channel, function with cure mainly: spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission; For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst; Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating; For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Herba Dendrobii: nature and flavor with return through: sweet, be slightly cold; Return stomach, kidney channel, function with cure mainly: reinforcing stomach reg fluid, nourishing YIN and clearing away heat; Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.
Radix Cynanchi Atrati: nature and flavor with return through: bitter, salty, cold; Return stomach, liver, kidney channel, function with cure mainly: clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome, detoxification sore treatment; For pathogenic warmth wound battalion heating, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, puerperal fever due to deficiency of blood, pyretic stranguria, stranguria with blood, swollen ulcer drug.
Fructus Viticis: nature and flavor with return through: pungent, bitter, be slightly cold; Return bladder, liver, stomach warp, function with cure mainly: dispelling wind and heat pathogens, the clear sharp head; For anemopyretic cold headache, gingivitis, the many tear of conjunctival congestion, poor vision, has a dizzy spell.
Radix Glehniae: nature and flavor with return through: sweet, micro-hardship, is slightly cold; Attach to the lung and stomach meridians, function with cure mainly: nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid; For lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound is thirsty.
Radix Stellariae: nature and flavor with return through: sweet, be slightly cold; Return liver, stomach warp, function with cure mainly: clearind deficient heat, dispelling fever with infantile malnutrition; For fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, children's's infantile malnutrition with fever.
Radix Saposhnikoviae: nature and flavor with return through acrid, sweet, warm; Return bladder, liver, spleen channel, function with cure mainly: inducing diaphoresis to dispel wind, victory is wet, relieving convulsion; For headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.
Cortex Phellodendri: nature and flavor with return through: bitter, cold; Return kidney, urinary bladder channel, function with cure mainly: heat clearing and damp drying, pathogenic fire purging except steam, detoxification sore treatment; For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus; Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire; For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Stamen Nelumbinis: nature and flavor with return through: sweet, puckery, flat; GUIXIN, kidney channel, function with cure mainly: reinforcing the kindey to control nocturnal emission; For emission and spermatorrhea, leukorrhagia, frequent micturition.
The Rhizoma Anemarrhenae: nature and flavor with return through: bitter, sweet, cold; Return lung, stomach, kidney channel, function with cure mainly: clearing away heat-fire, promote the production of body fluid and moisturize; For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Radix Glycyrrhizae: nature and flavor with return through: sweet, flat; GUIXIN, lung, spleen, stomach warp, function with cure mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription; For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Another technical problem to be solved by this invention is to provide a kind of preparation method preparing above-mentioned Chinese medicine oral liquid.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
Treat a preparation method for the Chinese medicine oral liquid that persistence low grade fever does not move back, be prepared from by following methods:
(1) get the raw material Radix Astragali, Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(2) get raw material Radix Pseudostellariae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(3) Radix Astragali after pulverizing in step (1), Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are added above-mentioned raw materials weight and 8-13 water doubly, decoct 2-3 hour, release medicinal liquid; Radix Pseudostellariae after pulverizing in step (2), Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, releases medicinal liquid; Add its weight 6-8 soak by water 1-2 hour doubly after twice medicinal residues merges, release medicinal liquid; Merge the medicinal liquid decocted for three times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(4) gained filtrate in step (3) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;
(5) filter in step (4) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;
(7) gained clear paste in step (6) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid that persistence low grade fever does not move back.
Preferably, a kind of preparation method for the treatment of the Chinese medicine oral liquid that persistence low grade fever does not move back, is prepared from by following methods:
(1) get the raw material Radix Astragali, Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30 mesh sieves, for subsequent use;
(2) get raw material Radix Pseudostellariae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30 mesh sieves, for subsequent use;
(3) Radix Astragali after pulverizing in step (1), Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are added the water of above-mentioned raw materials weight and 13 times, decocts 2 hours, releasing medicinal liquid; Radix Pseudostellariae after pulverizing in step (2), Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae are added the soak by water 2 hours of above-mentioned raw materials weight and 12 times, release medicinal liquid; Twice medicinal residues add the soak by water 1.5 hours of its weight 8 times after merging, release medicinal liquid; Merge the medicinal liquid decocted for three times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(4) gained filtrate in step (3) is added the ethanol of 95% of filtrate weight 1.5 times, leave standstill 24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane aperture of described leaf filter is 0.8 μm, in the process of filtering, pressure limit is 0.15MPa, face discharge is 1.5T/h, obtains filtrate, for subsequent use;
(5) filter in step (4) in gained filtrate feeding leaf filter, the filter membrane aperture of described leaf filter is 0.8 μm, and in the process of filtering, pressure limit is 0.15MPa, and face discharge is 0.8T/h, obtains filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into traditional Chinese drug inspissation machine, when being evaporated to 60 DEG C in thickener, the clear paste of relative density 1.05, obtains clear paste, for subsequent use;
(7) gained clear paste in step (6) is statically placed in 36 hours under the condition of 6 DEG C, by sodium hydroxide solution adjust ph to 6.5, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20min is irradiated in ultraviolet wavelength 254 sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid that persistence low grade fever does not move back.
Beneficial effect: the present invention has heat clearing and damp drying, eliminating fire and detoxication, brings down a fever except the effect of steaming, be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
The present invention adopts pure Chinese medicine to be raw material, the pathogenic factor of not moving back according to persistence low grade fever and Clinical symptoms, under instruction of Chinese Medicine theory, carry out prescription be prepared from the basis not being raw-material activity, show through clinical efficacy, this medicine does not move back definite curative effect to persistence low grade fever, is the ideal treatment medication that a kind of persistence low grade fever does not move back patient.
Model case
Case 1: Mrs Yang, 36 years old, medical history: continue low grade fever 37.5-38 DEG C, companioned with headache, malaise, takes Drug therapy of the present invention 3 days, the above-mentioned complete transference cure of patient, followed up a case by regular visits to 1 year without recurrence.
Case 2: Mrs Liu, 34 years old, medical history: the long-term low grade fever of patient main suit, examine and see patient's emaciated physique, the few China of complexion HUANGBAI(sic), the light profit of lip, in unable shape tired out, body temperature, through being everlasting between 37-37.5 DEG C, seldom rises to 38 DEG C, self-induction health is tired, lazy dynamic lazy speech, dynamic very then tired, breathe hard, or have sweating, inappetence, take Drug therapy of the present invention 3 days, symptom alleviates, and takes medicine of the present invention above-mentioned complete transference cure of patient after 6 days, follows up a case by regular visits to 1 year without recurrence.
Case 3: Mr. Zhang, 66 years old, medical history: more than patient's afternoon low grade fever moon, body temperature is between 37.5 DEG C-38 DEG C, and FUO, treats and have no an improvement in, examine, breast gastral cavity painful abdominal mass is vexed, indigestion and loss of appetite lack of appetite, sweating is weak, fever of the body is not understood, and take Drug therapy of the present invention 3 days, symptom alleviates, take medicine of the present invention above-mentioned complete transference cure of patient after 6 days, follow up a case by regular visits to 1 year without recurrence.
Case 4: Mrs Wang, 39 years old, medical history: more than low grade fever half a year, time have agitation, uncomfortable in chest swollen, consciously to breathe hard, kindly to sigh, take Drug therapy of the present invention 3 days, symptom alleviates, and takes medicine of the present invention above-mentioned complete transference cure of patient after 12 days, follows up a case by regular visits to 1 year without recurrence.
Case 5: Mr. Liu, 78 years old, medical history: patient main suit is over nearly 2 months, the sensation pit of the stomach was stuffy, and low grade fever does not move back, and take Drug therapy of the present invention 3 days, symptom alleviates, and takes medicine of the present invention above-mentioned complete transference cure of patient after 6 days, follows up a case by regular visits to 1 year without recurrence.
Case 6: sir, 40 years old, medical history: patient main suit continues low grade fever, body temperature is through being everlasting between 37-37.5 DEG C, self-induction health is tired, lazy dynamic lazy speech, dynamic very then tired, breathe hard, or have sweating, inappetence, strong food then distension does not disappear, and takes Drug therapy of the present invention 3 days above-mentioned complete transference cures of patient, follows up a case by regular visits to 1 year without recurrence.
Clinical data
Physical data: low grade fever patient 50 example, man 27 example, female 23 example, the age 19-78 year.
Diagnostic criteria: continue low grade fever, body temperature is at 37-38.5 DEG C;
Therapeutic Method: take oral liquid of the present invention, every day 2 times, each 30ml 3 days is a course for the treatment of.
Curative effect determinate standard: recovery from illness: every symptom all disappears, and without sense of discomfort, body temperature is normal; Effective: every symptom disappears substantially, without sense of discomfort, body temperature is normal; Invalid: to treat rear symptom, sign compared with before treatment without any change;
Therapeutic outcome: do not move back patient 50 example with this side treatment persistence low grade fever, wherein clinical recovery 45 example, effective 5 examples, invalid 0 example, effective percentage is 100%.
Detailed description of the invention
Embodiment 1
The present invention treats the preparation that persistence low grade fever does not move back Chinese medicine oral liquid, and each parts by weight of raw materials is: the Radix Astragali 32 parts, Radix Pseudostellariae 22 parts, Rhizoma Polygonati Odorati 22 parts, Radix Ophiopogonis 22 parts, Cortex Moutan 17 parts, Rhizoma Dioscoreae 32 parts, Herba Dendrobii 22 parts, Radix Cynanchi Atrati 17 parts, Fructus Viticis 14 parts, Radix Glehniae 32 parts, Radix Stellariae 17 parts, Radix Saposhnikoviae 12 parts, Cortex Phellodendri 17 parts, Stamen Nelumbinis 14 parts, the Rhizoma Anemarrhenae 17 parts, 8 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) get the raw material Radix Astragali, Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(2) get raw material Radix Pseudostellariae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(3) Radix Astragali after pulverizing in step (1), Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are added above-mentioned raw materials weight and 8-13 water doubly, decoct 2-3 hour, release medicinal liquid; Radix Pseudostellariae after pulverizing in step (2), Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, releases medicinal liquid; Add its weight 6-8 soak by water 1-2 hour doubly after twice medicinal residues merges, release medicinal liquid; Merge the medicinal liquid decocted for three times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(4) gained filtrate in step (3) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;
(5) filter in step (4) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;
(7) gained clear paste in step (6) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid that persistence low grade fever does not move back.
Usage: oral, every day 2 times, each 30ml.
Embodiment 2
The present invention treats the preparation that persistence low grade fever does not move back Chinese medicine oral liquid, and each parts by weight of raw materials is: the Radix Astragali 30 parts, Radix Pseudostellariae 20 parts, Rhizoma Polygonati Odorati 20 parts, Radix Ophiopogonis 20 parts, Cortex Moutan 15 parts, Rhizoma Dioscoreae 30 parts, Herba Dendrobii 20 parts, Radix Cynanchi Atrati 15 parts, Fructus Viticis 12 parts, Radix Glehniae 30 parts, Radix Stellariae 15 parts, Radix Saposhnikoviae 10 parts, Cortex Phellodendri 15 parts, Stamen Nelumbinis 12 parts, the Rhizoma Anemarrhenae 15 parts, 6 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) get the raw material Radix Astragali, Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(2) get raw material Radix Pseudostellariae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(3) Radix Astragali after pulverizing in step (1), Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are added above-mentioned raw materials weight and 8-13 water doubly, decoct 2-3 hour, release medicinal liquid; Radix Pseudostellariae after pulverizing in step (2), Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, releases medicinal liquid; Add its weight 6-8 soak by water 1-2 hour doubly after twice medicinal residues merges, release medicinal liquid; Merge the medicinal liquid decocted for three times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(4) gained filtrate in step (3) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;
(5) filter in step (4) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;
(7) gained clear paste in step (6) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid that persistence low grade fever does not move back.
Usage: oral, every day 2 times, each 30ml.
Embodiment 3
The present invention treats the preparation that persistence low grade fever does not move back Chinese medicine oral liquid, and each parts by weight of raw materials is: the Radix Astragali 28 parts, Radix Pseudostellariae 18 parts, Rhizoma Polygonati Odorati 18 parts, Radix Ophiopogonis 18 parts, Cortex Moutan 13 parts, Rhizoma Dioscoreae 28 parts, Herba Dendrobii 18 parts, Radix Cynanchi Atrati 13 parts, Fructus Viticis 10 parts, Radix Glehniae 28 parts, Radix Stellariae 13 parts, Radix Saposhnikoviae 8 parts, Cortex Phellodendri 13 parts, Stamen Nelumbinis 10 parts, the Rhizoma Anemarrhenae 13 parts, 4 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) get the raw material Radix Astragali, Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(2) get raw material Radix Pseudostellariae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(3) Radix Astragali after pulverizing in step (1), Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are added above-mentioned raw materials weight and 8-13 water doubly, decoct 2-3 hour, release medicinal liquid; Radix Pseudostellariae after pulverizing in step (2), Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, releases medicinal liquid; Add its weight 6-8 soak by water 1-2 hour doubly after twice medicinal residues merges, release medicinal liquid; Merge the medicinal liquid decocted for three times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(4) gained filtrate in step (3) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;
(5) filter in step (4) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;
(7) gained clear paste in step (6) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid that persistence low grade fever does not move back.
Usage: oral, every day 2 times, each 30ml.
Claims (6)
1. treat the Chinese medicine oral liquid that persistence low grade fever does not move back, it is characterized in that: be made up of following raw material: Radix Astragali 28-32 part, Radix Pseudostellariae 18-22 part, Rhizoma Polygonati Odorati 18-22 part, Radix Ophiopogonis 18-22 part, Cortex Moutan 13-17 part, Rhizoma Dioscoreae 18-32 part, Herba Dendrobii 18-22 part, Radix Cynanchi Atrati 13-17 part, Fructus Viticis 10-14 part, Radix Glehniae 28-32 part, Radix Stellariae 13-17 part, Radix Saposhnikoviae 8-12 part, Cortex Phellodendri 13-17 part, Stamen Nelumbinis 10-14 part, Rhizoma Anemarrhenae 13-17 part, Radix Glycyrrhizae 4-8 part.
2. a kind of Chinese medicine oral liquid for the treatment of persistence low grade fever and not moving back according to claim 1, is characterized in that: the weight portion of each raw material is: the Radix Astragali 30 parts, Radix Pseudostellariae 20 parts, Rhizoma Polygonati Odorati 20 parts, Radix Ophiopogonis 20 parts, Cortex Moutan 15 parts, Rhizoma Dioscoreae 30 parts, Herba Dendrobii 20 parts, Radix Cynanchi Atrati 15 parts, Fructus Viticis 12 parts, Radix Glehniae 30 parts, Radix Stellariae 15 parts, Radix Saposhnikoviae 10 parts, Cortex Phellodendri 15 parts, Stamen Nelumbinis 12 parts, the Rhizoma Anemarrhenae 15 parts, 6 parts, Radix Glycyrrhizae.
3. a kind of Chinese medicine oral liquid for the treatment of persistence low grade fever and not moving back according to claim 1, is characterized in that: the weight portion of each raw material is: the Radix Astragali 32 parts, Radix Pseudostellariae 22 parts, Rhizoma Polygonati Odorati 22 parts, Radix Ophiopogonis 22 parts, Cortex Moutan 17 parts, Rhizoma Dioscoreae 32 parts, Herba Dendrobii 22 parts, Radix Cynanchi Atrati 17 parts, Fructus Viticis 14 parts, Radix Glehniae 32 parts, Radix Stellariae 17 parts, Radix Saposhnikoviae 12 parts, Cortex Phellodendri 17 parts, Stamen Nelumbinis 14 parts, the Rhizoma Anemarrhenae 17 parts, 8 parts, Radix Glycyrrhizae.
4. a kind of Chinese medicine oral liquid for the treatment of persistence low grade fever and not moving back according to claim 1, is characterized in that: the weight portion of each raw material is: the Radix Astragali 28 parts, Radix Pseudostellariae 18 parts, Rhizoma Polygonati Odorati 18 parts, Radix Ophiopogonis 18 parts, Cortex Moutan 13 parts, Rhizoma Dioscoreae 28 parts, Herba Dendrobii 18 parts, Radix Cynanchi Atrati 13 parts, Fructus Viticis 10 parts, Radix Glehniae 28 parts, Radix Stellariae 13 parts, Radix Saposhnikoviae 8 parts, Cortex Phellodendri 13 parts, Stamen Nelumbinis 10 parts, the Rhizoma Anemarrhenae 13 parts, 4 parts, Radix Glycyrrhizae.
5. a kind of preparation method for the treatment of the Chinese medicine oral liquid that persistence low grade fever does not move back according to claim 1 and 2, is characterized in that: be prepared from by following methods:
Be prepared from by following methods:
(1) get the raw material Radix Astragali, Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(2) get raw material Radix Pseudostellariae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(3) Radix Astragali after pulverizing in step (1), Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are added above-mentioned raw materials weight and 8-13 water doubly, decoct 2-3 hour, release medicinal liquid; Radix Pseudostellariae after pulverizing in step (2), Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, releases medicinal liquid; Add its weight 6-8 soak by water 1-2 hour doubly after twice medicinal residues merges, release medicinal liquid; Merge the medicinal liquid decocted for three times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(4) gained filtrate in step (3) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;
(5) filter in step (4) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;
(7) gained clear paste in step (6) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid that persistence low grade fever does not move back.
6. a kind of preparation method for the treatment of the Chinese medicine oral liquid that persistence low grade fever does not move back according to claim 1 and 2, is characterized in that: be prepared from by following methods:
Be prepared from by following methods:
(1) get the raw material Radix Astragali, Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30 mesh sieves, for subsequent use;
(2) get raw material Radix Pseudostellariae, Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30 mesh sieves, for subsequent use;
(3) Radix Astragali after pulverizing in step (1), Cortex Moutan, Herba Dendrobii, Radix Cynanchi Atrati, Fructus Viticis, Radix Stellariae, Radix Saposhnikoviae, Cortex Phellodendri, Stamen Nelumbinis, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are added the water of above-mentioned raw materials weight and 13 times, decocts 2 hours, releasing medicinal liquid; Radix Pseudostellariae after pulverizing in step (2), Rhizoma Polygonati Odorati, Radix Ophiopogonis, Rhizoma Dioscoreae, Radix Glehniae are added the soak by water 2 hours of above-mentioned raw materials weight and 12 times, release medicinal liquid; Twice medicinal residues add the soak by water 1.5 hours of its weight 8 times after merging, release medicinal liquid; Merge the medicinal liquid decocted for three times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(4) gained filtrate in step (3) is added the ethanol of 95% of filtrate weight 1.5 times, leave standstill 24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane aperture of described leaf filter is 0.8 μm, in the process of filtering, pressure limit is 0.15MPa, face discharge is 1.5T/h, obtains filtrate, for subsequent use;
(5) filter in step (4) in gained filtrate feeding leaf filter, the filter membrane aperture of described leaf filter is 0.8 μm, and in the process of filtering, pressure limit is 0.15MPa, and face discharge is 0.8T/h, obtains filtrate, for subsequent use;
(6) gained filtrate in step (5) is sent into traditional Chinese drug inspissation machine, when being evaporated to 60 DEG C in thickener, the clear paste of relative density 1.05, obtains clear paste, for subsequent use;
(7) gained clear paste in step (6) is statically placed in 36 hours under the condition of 6 DEG C, by sodium hydroxide solution adjust ph to 6.5, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20min is irradiated in ultraviolet wavelength 254 sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid that persistence low grade fever does not move back.
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| CN106266908A (en) * | 2016-08-05 | 2017-01-04 | 李胜利 | A kind of medicine treating persistence low grade fever |
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