CN106266739A - A kind of Chinese medicine preparation treating spontaneous sweating and preparation method - Google Patents

A kind of Chinese medicine preparation treating spontaneous sweating and preparation method Download PDF

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Publication number
CN106266739A
CN106266739A CN201610992063.9A CN201610992063A CN106266739A CN 106266739 A CN106266739 A CN 106266739A CN 201610992063 A CN201610992063 A CN 201610992063A CN 106266739 A CN106266739 A CN 106266739A
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parts
radix
raw material
fructus
standby
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黄烜
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Dongguan Biological Technology Co Ltd
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Dongguan Biological Technology Co Ltd
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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    • A61K36/06Fungi, e.g. yeasts
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    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

nullThe invention discloses a kind of Chinese medicine preparation treating spontaneous sweating and preparation method,It is made up of the raw material of following weight portion: the Radix Astragali 120 180 parts、Radix Ephedrae 10 70 parts、Radix Pseudostellariae 70 130 parts、Fructus Corni 70 130 parts、Concha Ostreae (calcined) 150 210 parts、Fructus Tritici Levis 120 180 parts、Ganoderma 30 90 parts、The Radix Paeoniae Alba 40 100 parts、40 100 parts of Folium Mori、Fructus Schisandrae Chinensis 20 80 parts、Fructus Mori 20 80 parts、Radix Rhodiolae 10 50 parts、Semen Oroxyli 10 50 parts、Radix Glycyrrhizae Preparata 10 50 parts、Cortex Lycii 20 80 parts、Radix Oryzae Glutinosae 70 130 parts、Cortex Moutan 20 80 parts、20 80 parts of Poria、Rhizoma Atractylodis Macrocephalae (parched) 20 80 parts、Acesulfame potassium 0.001 0.002 parts、Sodium benzoate 0.001 0.002 parts、0.001 0.0016 parts of essence.This Chinese medicine preparation has QI invigorating, solid wet, effect of arresting sweating, determined curative effect, and effective percentage is high, safety non-toxic.

Description

A kind of Chinese medicine preparation treating spontaneous sweating and preparation method
Technical field
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation treating spontaneous sweating and preparation method.
Background technology
Spontaneous perspiration, night sweat refer to that yin-Yang is lacked of proper care, disharmony of nutrient QI with defensive QI, and the perspiration that space between skin and muscles is given away secrets and caused leaks;Sweating constantly, Dynamic then benefit is notably spontaneous perspiration;Sweating in sleep, after waking up, perspiration stopped person is night sweat;Often by caused by autonomic nervous dysfunction;It is clinical Feature is not because of the impact of outside environmental elements, and sweating constantly in daytime, benefit is notably referred to as spontaneous perspiration easily;Sleep middle sweating, after waking up From only, referred to as night sweat, primary disease is equivalent to the hyperthyroidism of doctor trained in Western medicine, autonomic nervous dysfunction, rheumatic fever, tuberculosis Deng;Spontaneous perspiration, the cause of disease of night sweat be divided into inside and outside because of, its endogenous cause of ill person be that body is empty after being ill, exterior deficiency wind-engaging, ponder over and bother excessively, feelings will Not relaxing, addiction is pungent caused;Exopathogenic factor person attacks for outside ailment said due to cold or exposure, and its sick position is defended at lung, relevant with liver;Basic pathogenesis be insufficiency of lung-QI or Disharmony of nutrient QI with defensive QI, defends outer mistake department;Hyperactivity of fire caused by deficiency of YIN or pathogenic heat hot and suffocating, force Tianjin to leak caused;Spontaneous perspiration, pathologic feature many genus void of night sweat Card, general spontaneous perspiration mostly is the deficiency of vital energy, and night sweat mostly is the deficiency of YIN, spontaneous perspiration with the passing of time, cloudy liquid virtual loss, the most concurrent night sweat;True card person, with liver-fire Or caused by retention and fumigation of damp-heat inside the body;Spontaneous perspiration is the (1) cause of disease with the diagnosis basis of night sweat: has body void, exterior deficiency wind-engaging after being ill, ponders over and bother excessively, Feelings will is not relaxed, and addiction is pungent etc. is prone to cause the cause of disease of spontaneous sweating to exist;(2) clinical manifestation: do not affect because of external environment, Head, neck breast or extremity, panhidrosis person, Qi, day sweating Qi, dynamic then benefit very spontaneous perspiration, sweating Jin Jin in sleep, after waking up Perspiration stopped is night sweat;2. spontaneous perspiration that except, other diseases causes, night sweat, as the spontaneous perspiration occurred during other diseases, night sweat, because of The difference of disease, respectively has symptom and the sign of this disease, and perspiration scarcely occupy prominent position;At present, Chinese medicine Spontaneous sweating research report is increasing, is accepted by vast spontaneous sweating patient because its side effect is little;But make a general survey of in recent years Research overview, remains in many problems, and such as decoction, plus-minus person is many, and fixed dosage form person is few etc.;Particularly to mechanism of drug action, There is not been reported for the animal experiment study of the aspects such as link;In view of this, utilize modern science and technology equipment and method, inquire into spontaneous perspiration and steal Antiperspirant etiology and pathogenesis, screening verification active drug, develop with strong points, curative effect affirmative, the Chinese medicine preparation of dosage form simplicity, be the most urgently Key issue to be solved.
Summary of the invention
For the deficiencies in the prior art, it is an object of the invention to provide a kind of taking convenience, be easy to carry, the controlling of clothes the most for a long time Treating Chinese medicine composition and the preparation method of spontaneous sweating, this Chinese medicine preparation has QI invigorating, consolidates wet, effect of arresting sweating, determined curative effect, Effective percentage is high, safety non-toxic.
For solving above-mentioned technical problem, the present invention provides a kind of Chinese medicine preparation treating spontaneous sweating, by following weight portion Raw material make: Radix Astragali 120-180 part, Radix Ephedrae 10-70 part, Radix Pseudostellariae 70-130 part, Fructus Corni 70-130 part, Concha Ostreae (calcined) 150- 210 parts, Fructus Tritici Levis 120-180 part, Ganoderma 30-90 part, Radix Paeoniae Alba 40-100 part, Folium Mori 40-100 part, Fructus Schisandrae Chinensis 20-80 part, Mulberry Mulberry 20-80 part, Radix Rhodiolae 10-50 part, Semen Oroxyli 10-50 part, Radix Glycyrrhizae Preparata 10-50 part, Cortex Lycii 20-80 part, Radix Oryzae Glutinosae 70- 130 parts, Cortex Moutan 20-80 part, Poria 20-80 part, Rhizoma Atractylodis Macrocephalae (parched) 20-80 part, acesulfame potassium 0.001-0.002 part, sodium benzoate 0.001-0.002 part, essence 0.001-0.0016 part;
Its preparation process is:
(1) take raw material Concha Ostreae (calcined) and be ground into 100-180 mesh, standby;
(2) take raw material Ganoderma to pulverize, be ground into 260-300 mesh, standby;
(3) take the raw material Radix Astragali, Radix Ephedrae, Radix Pseudostellariae, Fructus Corni mixing, be ground into 50-80 mesh, obtain raw material powder, standby;
(4) take raw material Fructus Schisandrae Chinensis, Fructus Mori, Radix Rhodiolae, Semen Oroxyli, Radix Glycyrrhizae Preparata, Cortex Lycii, Radix Oryzae Glutinosae, Cortex Moutan, Poria, float Semen Tritici aestivi, Rhizoma Atractylodis Macrocephalae (parched), the Radix Paeoniae Alba, Folium Mori mixing, be ground into 50-80 mesh, obtain raw material powder, standby;
(5) add water 6-10 times into raw material total amount by the Ganoderma after pulverizing in the Concha Ostreae (calcined) after middle for step (1) pulverizing, step (2), Decocting 25-55 minute, pour out medicinal liquid, medicinal residues mix decoction with the raw material powder of gained in step (3), in step (4), add water as former 10-14 times of material gross weight, decocts 25-55 minute, pours out medicinal liquid, and add water into raw material gross weight 5-8 times again, decocts 25- 55 minutes, merging three medicinal liquids, filter, being evaporated to 55-65 DEG C and surveying relative density is the clear paste of 1.05-1.15, standby;
(6) gained clear paste in step (5) is added the ethanol of 15% by volume, static 12-24 hour, fling to ethanol, after Filter, being further concentrated to 80-90 DEG C and surveying relative density is the extractum of 1.15-1.20, is placed in-5 to 0 DEG C freezing 48-72 hour, standby With;
(7) take raw material acesulfame potassium, sodium benzoate, essence are respectively crushed into 200-300 mesh, standby;
(8) gained extractum in step (6) being added pure water, amount of water is 6-9 times of its weight, stirs 15-in agitator tank 20 minutes, stand 4-8 hour, be stirred for 15-20 minute, make serosity flow into 325-360 mesh sieve hole reciprocating sieve while stirring and filter, Obtain filtrate, in filtrate, add acesulfame potassium and sodium benzoate after pulverizing, add essence after pulverizing after stirring 15-20 minute, then stir Mix 15-20 minute, finally under conditions of 4-8 DEG C, stand 12-24 hour, filter, by filtrate fill, sterilizing, must treat certainly The Chinese medicine preparation of antiperspirant night sweat.
Preferably in scheme, a kind of Chinese medicine preparation treating spontaneous sweating, it is made up of the raw material of following weight portion: the Radix Astragali 150 parts, Radix Ephedrae 40 parts, Radix Pseudostellariae 100 parts, Fructus Corni 100 parts, Concha Ostreae (calcined) 180 parts, Fructus Tritici Levis 150 parts, Ganoderma 60 parts, the Radix Paeoniae Alba 70 parts, 70 parts of Folium Mori, Fructus Schisandrae Chinensis 50 parts, Fructus Mori 50 parts, Radix Rhodiolae 30 parts, Semen Oroxyli 30 parts, Radix Glycyrrhizae Preparata 30 parts, Cortex Lycii 50 Part, Radix Oryzae Glutinosae 100 parts, Cortex Moutan 50 parts, 50 parts of Poria, Rhizoma Atractylodis Macrocephalae (parched) 50 parts, acesulfame potassium 0.0015 part, sodium benzoate 0.0015 Part, 0.0013 part of essence;
Its preparation process is:
(1) take raw material Concha Ostreae (calcined) and be ground into 180 mesh, standby;
(2) take raw material Ganoderma to pulverize, be ground into 260 mesh, standby;
(3) take the raw material Radix Astragali, Radix Ephedrae, Radix Pseudostellariae, Fructus Corni mixing, be ground into 80 mesh, obtain raw material powder, standby;
(4) take raw material Fructus Schisandrae Chinensis, Fructus Mori, Radix Rhodiolae, Semen Oroxyli, Radix Glycyrrhizae Preparata, Cortex Lycii, Radix Oryzae Glutinosae, Cortex Moutan, Poria, float Semen Tritici aestivi, Rhizoma Atractylodis Macrocephalae (parched), the Radix Paeoniae Alba, Folium Mori mixing, be ground into 50 mesh, obtain raw material powder, standby;
(5) add water 10 times into raw material total amount by the Ganoderma after pulverizing in the Concha Ostreae (calcined) after middle for step (1) pulverizing, step (2), decocts Boiling 45 minutes, pour out medicinal liquid, medicinal residues mix decoction with the raw material powder of gained in step (3), in step (4), add water total into raw material 10 times of weight, decoct 45 minutes, pour out medicinal liquid, and add water into raw material gross weight 8 times again, decoct 35 minutes, merge three times Medicinal liquid, filters, and being evaporated to 65 DEG C and surveying relative density is the clear paste of 1.05, standby;
(6) gained clear paste in step (5) is added the ethanol of 15% by volume, static 12 hours, fling to ethanol, refilter, then Being concentrated into 80 DEG C and surveying relative density is the extractum of 1.15, is placed in-5 DEG C of freezings 48 hours, standby;
(7) take raw material acesulfame potassium, sodium benzoate, essence are respectively crushed into 300 mesh, standby;
(8) gained extractum in step (6) being added pure water, amount of water is 6 times of its weight, stirs 20 points in agitator tank Clock, stands 8 hours, is stirred for 20 minutes, makes serosity flow into 360 mesh sieve hole reciprocating sieves while stirring and filters, obtains filtrate, to filtrate Acesulfame potassium and sodium benzoate after middle addition pulverizing, add essence after pulverizing, be stirred for 20 minutes, finally 8 after stirring 20 minutes Stand 12 hours under conditions of DEG C, filter, by filtrate fill, sterilizing, the Chinese medicine preparation of spontaneous sweating must be treated.
Used by the present invention, the pharmacology of raw material of Chinese medicine medicine is as follows:
The Radix Astragali: meridian distribution of property and flavor: sweet, temperature, return lung, spleen channel;Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation;With Weak in the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, for a long time Bursting and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst;Chronic nephritis proteinuria, diabetes.
Radix Ephedrae: meridian distribution of property and flavor: hardship pungent, micro-, temperature, return lung, bladder warp;Function cures mainly: diaphoresis cold expelling, depressed lung-energy dispersing, profit Water is subsided a swelling;For anemofrigid cold, uncomfortable in chest breath with cough, edema due to wind pathogen edema;Bronchial asthma;Herba ephedrae nourishing the lung to arrest cough;It is used for table disease Solve, asthma and cough.
Radix Pseudostellariae: meridian distribution of property and flavor: hardship sweet, micro-, flat, return spleen, lung meridian;Function cures mainly: replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung;For Insufficiency of the spleen body is tired, inappetence, and weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough.
Fructus Corni: meridian distribution of property and flavor: sour, puckery, tepor, return liver, kidney channel;Function cures mainly: liver and kidney tonifying, restrains astringent or styptic treatment for spontaneous sweating, and controlling nocturnal emission with astringent drugs contracts Urine, leukorrhagia stopping only collapses, hidroschesis, in addition with promoting the production of body fluid to quench thirst;For soreness of waist and knee joint, dizziness and tinnitus, forgetful, emission and spermatorrhea, the enuresis is urinated Frequently, bleeding not during menses, menoxenia, profuse sweating collapse, interior-heat is quenched one's thirst.
Concha Ostreae (calcined): nature and flavor, salty in the mouth, cold nature, return Liver Channel, kidney channel: function cures mainly: yin fluid astringing YANG hyperactivity suppressing, hidroschesis arresting seminal emission, reduces phlegm soft Hard;Control infantile convulsion, spontaneous sweating, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter, vertigo and tinnitus, abdominal mass mass in the abdomen, pantothenic acid of having a stomachache;Forge Concha Ostreae convergence is astringent or styptic treatment for spontaneous sweating.
Fructus Tritici Levis: meridian distribution of property and flavor: sweet, cool, GUIXIN warp;Effect: hidroschesis, QI invigorating, heat extraction;Cure mainly: for spontaneous perspiration, night sweat, Osteopyrexia and fever.
Ganoderma: meridian distribution of property and flavor: sweet, flat, GUIXIN, lung, liver, kidney channel;Cure mainly asthenia, cough, pant, have a sleepless night, dyspepsia, Malignant tumor etc..
The Radix Paeoniae Alba: meridian distribution of property and flavor: bitter, sour, is slightly cold, and returns liver, spleen channel;Function cures mainly: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, and yin fluid astringing is only Antiperspirant;For dizziness of having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Folium Mori: meridian distribution of property and flavor: sweet, bitter, cold, return lung, Liver Channel;Function cures mainly: dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving; For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.
Fructus Schisandrae Chinensis: meridian distribution of property and flavor: sour, sweet, temperature, return lung, the heart, kidney channel;Function cures mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, the kidney invigorating Mind calming;For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, deficient pulse of losing heart, interior-heat Quench one's thirst, palpitation and insomnia.
Fructus Mori: nature and flavor: sweet in the mouth, cold in nature, Gui Jing: enter the heart, liver, kidney channel;Function: nourishing YIN and supplementing blood, improving eyesight promotes the production of body fluid, intestine moistening; Curing mainly: weakness due to chronic disease, hepatic and renal YIN deficiency, soreness of the waist and knees, the dark tinnitus of mesh, articular instability, dryness of the intestine constipation, body fluid deficiency insufficiency of blood, hectic fever is passed out semen, Diabetes etc..
Radix Rhodiolae: nature and flavor: cold, sweet, puckery, return lung meridian, has QI invigorating lung heat clearing, Fructus Alpiniae Oxyphyllae is nourished heart, hemostasis with astringents, dissipating blood stasis for subsidence of swelling Effect;Main deficiency of vital energy and physically weak, after being ill fear of cold, shortness of breath and fatigue, cough due to lung-heat, spitting of blood, leucorrhea diarrhoea, traumatic injury, burn and scald, neural Disease, altitude sickness.
Semen Oroxyli: meridian distribution of property and flavor: bitter, sweet, cool, return lung, liver, stomach warp;Function cures mainly: removing heat from the lung and relieving sorethroat, dispersing the stagnated liver-QI for regulating the stomach;For Cough due to lung-heat, sore throat, hoarseness, stomachache due to hyperactive liver-QI attacking the stomach.
Radix Glycyrrhizae Preparata: property is flat, sweet in the mouth, GUIXIN, spleen, lung, stomach warp;Effect: tonification;Function cures mainly: invigorating the spleen and replenishing QI, heat clearing away solution Poison, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription;For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, four Limb contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
Cortex Lycii: meridian distribution of property and flavor: sweet, cold, return lung, liver, kidney channel;Function cures mainly: removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing;For the moon Empty hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst.
Radix Oryzae Glutinosae: nature and flavor sweet in the mouth, property is put down, is returned through GUIXIN, Liver Channel;Effect yin nourishing, hidroschesis, stomach invigorating;Cure mainly spontaneous perspiration, night sweat, Hepatitis, chyluria.
Cortex Moutan: meridian distribution of property and flavor: bitter, pungent, is slightly cold, GUIXIN, liver, kidney channel;Function cures mainly: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling;With In maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, fall and flutter the pain of injury.
Poria: meridian distribution of property and flavor: sweet, light, flat, GUIXIN, lung, spleen, kidney channel;Function cures mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming;With In edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool has loose bowels, irritability, palpitation with fear insomnia.
Rhizoma Atractylodis Macrocephalae (parched): meridian distribution of property and flavor: bitter, sweet, temperature, return spleen, stomach warp;Function cures mainly: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, peace Tire;For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement;Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive;With In insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
Beneficial effects of the present invention: having QI invigorating, solid wet, effect of arresting sweating, determined curative effect, effective percentage is high, safety non-toxic.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
Embodiment 1
A kind of Chinese medicine preparation treating spontaneous sweating, is made up of the raw material of following weight portion: the Radix Astragali 180 parts, Radix Ephedrae 70 parts, too Son ginseng 130 parts, Fructus Corni 130 parts, Concha Ostreae (calcined) 210 parts, Fructus Tritici Levis 180 parts, Ganoderma 90 parts, the Radix Paeoniae Alba 100 parts, 100 parts of Folium Mori, the five tastes Son 80 parts, Fructus Mori 80 parts, Radix Rhodiolae 50 parts, Semen Oroxyli 50 parts, Radix Glycyrrhizae Preparata 50 parts, Cortex Lycii 80 parts, Radix Oryzae Glutinosae 130 parts, male Cortex Moutan 80 parts, 80 parts of Poria, Rhizoma Atractylodis Macrocephalae (parched) 80 parts, acesulfame potassium 0.002 part, sodium benzoate 0.002 part, 0.0016 part of essence;
Its preparation process is:
(1) take raw material Concha Ostreae (calcined) and be ground into 100-180 mesh, standby;
(2) take raw material Ganoderma to pulverize, be ground into 260-300 mesh, standby;
(3) take the raw material Radix Astragali, Radix Ephedrae, Radix Pseudostellariae, Fructus Corni mixing, be ground into 50-80 mesh, obtain raw material powder, standby;
(4) take raw material Fructus Schisandrae Chinensis, Fructus Mori, Radix Rhodiolae, Semen Oroxyli, Radix Glycyrrhizae Preparata, Cortex Lycii, Radix Oryzae Glutinosae, Cortex Moutan, Poria, float Semen Tritici aestivi, Rhizoma Atractylodis Macrocephalae (parched), the Radix Paeoniae Alba, Folium Mori mixing, be ground into 50-80 mesh, obtain raw material powder, standby;
(5) add water 6-10 times into raw material total amount by the Ganoderma after pulverizing in the Concha Ostreae (calcined) after middle for step (1) pulverizing, step (2), Decocting 25-55 minute, pour out medicinal liquid, medicinal residues mix decoction with the raw material powder of gained in step (3), in step (4), add water as former 10-14 times of material gross weight, decocts 25-55 minute, pours out medicinal liquid, and add water into raw material gross weight 5-8 times again, decocts 25- 55 minutes, merging three medicinal liquids, filter, being evaporated to 55-65 DEG C and surveying relative density is the clear paste of 1.05-1.15, standby;
(6) gained clear paste in step (5) is added the ethanol of 15% by volume, static 12-24 hour, fling to ethanol, after Filter, being further concentrated to 80-90 DEG C and surveying relative density is the extractum of 1.15-1.20, is placed in-5 to 0 DEG C freezing 48-72 hour, standby With;
(7) take raw material acesulfame potassium, sodium benzoate, essence are respectively crushed into 200-300 mesh, standby;
(8) gained extractum in step (6) being added pure water, amount of water is 6-9 times of its weight, stirs 15-in agitator tank 20 minutes, stand 4-8 hour, be stirred for 15-20 minute, make serosity flow into 325-360 mesh sieve hole reciprocating sieve while stirring and filter, Obtain filtrate, in filtrate, add acesulfame potassium and sodium benzoate after pulverizing, add essence after pulverizing after stirring 15-20 minute, then stir Mix 15-20 minute, finally under conditions of 4-8 DEG C, stand 12-24 hour, filter, by filtrate fill, sterilizing, must treat certainly The Chinese medicine preparation of antiperspirant night sweat.
Usage: oral, every day 2 times, each 15ml.
Embodiment 2
A kind of Chinese medicine preparation treating spontaneous sweating, is made up of the raw material of following weight portion: the Radix Astragali 150 parts, Radix Ephedrae 40 parts, too Son ginseng 100 parts, Fructus Corni 100 parts, Concha Ostreae (calcined) 180 parts, Fructus Tritici Levis 150 parts, Ganoderma 60 parts, the Radix Paeoniae Alba 70 parts, 70 parts of Folium Mori, Fructus Schisandrae Chinensis 50 parts, Fructus Mori 50 parts, Radix Rhodiolae 30 parts, Semen Oroxyli 30 parts, Radix Glycyrrhizae Preparata 30 parts, Cortex Lycii 50 parts, Radix Oryzae Glutinosae 100 parts, Paeonia suffruticosa Skin 50 parts, 50 parts of Poria, Rhizoma Atractylodis Macrocephalae (parched) 50 parts, acesulfame potassium 0.0015 part, sodium benzoate 0.0015 part, 0.0013 part of essence;
Its preparation process is:
(1) take raw material Concha Ostreae (calcined) and be ground into 100-180 mesh, standby;
(2) take raw material Ganoderma to pulverize, be ground into 260-300 mesh, standby;
(3) take the raw material Radix Astragali, Radix Ephedrae, Radix Pseudostellariae, Fructus Corni mixing, be ground into 50-80 mesh, obtain raw material powder, standby;
(4) take raw material Fructus Schisandrae Chinensis, Fructus Mori, Radix Rhodiolae, Semen Oroxyli, Radix Glycyrrhizae Preparata, Cortex Lycii, Radix Oryzae Glutinosae, Cortex Moutan, Poria, float Semen Tritici aestivi, Rhizoma Atractylodis Macrocephalae (parched), the Radix Paeoniae Alba, Folium Mori mixing, be ground into 50-80 mesh, obtain raw material powder, standby;
(5) add water 6-10 times into raw material total amount by the Ganoderma after pulverizing in the Concha Ostreae (calcined) after middle for step (1) pulverizing, step (2), Decocting 25-55 minute, pour out medicinal liquid, medicinal residues mix decoction with the raw material powder of gained in step (3), in step (4), add water as former 10-14 times of material gross weight, decocts 25-55 minute, pours out medicinal liquid, and add water into raw material gross weight 5-8 times again, decocts 25- 55 minutes, merging three medicinal liquids, filter, being evaporated to 55-65 DEG C and surveying relative density is the clear paste of 1.05-1.15, standby;
(6) gained clear paste in step (5) is added the ethanol of 15% by volume, static 12-24 hour, fling to ethanol, after Filter, being further concentrated to 80-90 DEG C and surveying relative density is the extractum of 1.15-1.20, is placed in-5 to 0 DEG C freezing 48-72 hour, standby With;
(7) take raw material acesulfame potassium, sodium benzoate, essence are respectively crushed into 200-300 mesh, standby;
(8) gained extractum in step (6) being added pure water, amount of water is 6-9 times of its weight, stirs 15-in agitator tank 20 minutes, stand 4-8 hour, be stirred for 15-20 minute, make serosity flow into 325-360 mesh sieve hole reciprocating sieve while stirring and filter, Obtain filtrate, in filtrate, add acesulfame potassium and sodium benzoate after pulverizing, add essence after pulverizing after stirring 15-20 minute, then stir Mix 15-20 minute, finally under conditions of 4-8 DEG C, stand 12-24 hour, filter, by filtrate fill, sterilizing, must treat certainly The Chinese medicine preparation of antiperspirant night sweat.
Usage: oral, every day 2 times, each 15ml.
Embodiment 3
A kind of Chinese medicine preparation treating spontaneous sweating, is made up of the raw material of following weight portion: the Radix Astragali 120 parts, Radix Ephedrae 10 parts, too Son ginseng 70 parts, Fructus Corni 70-130 part, Concha Ostreae (calcined) 150 parts, Fructus Tritici Levis 120 parts, Ganoderma 30 parts, the Radix Paeoniae Alba 40 parts, 40 parts of Folium Mori, the five tastes Son 20 parts, Fructus Mori 20 parts, Radix Rhodiolae 10 parts, Semen Oroxyli 10 parts, Radix Glycyrrhizae Preparata 10 parts, Cortex Lycii 20 parts, Radix Oryzae Glutinosae 70 parts, Paeonia suffruticosa Skin 20 parts, 20 parts of Poria, Rhizoma Atractylodis Macrocephalae (parched) 20 parts, acesulfame potassium 0.001 part, sodium benzoate 0.001 part, 0.001 part of essence;
Its preparation process is:
(1) take raw material Concha Ostreae (calcined) and be ground into 100-180 mesh, standby;
(2) take raw material Ganoderma to pulverize, be ground into 260-300 mesh, standby;
(3) take the raw material Radix Astragali, Radix Ephedrae, Radix Pseudostellariae, Fructus Corni mixing, be ground into 50-80 mesh, obtain raw material powder, standby;
(4) take raw material Fructus Schisandrae Chinensis, Fructus Mori, Radix Rhodiolae, Semen Oroxyli, Radix Glycyrrhizae Preparata, Cortex Lycii, Radix Oryzae Glutinosae, Cortex Moutan, Poria, float Semen Tritici aestivi, Rhizoma Atractylodis Macrocephalae (parched), the Radix Paeoniae Alba, Folium Mori mixing, be ground into 50-80 mesh, obtain raw material powder, standby;
(5) add water 6-10 times into raw material total amount by the Ganoderma after pulverizing in the Concha Ostreae (calcined) after middle for step (1) pulverizing, step (2), Decocting 25-55 minute, pour out medicinal liquid, medicinal residues mix decoction with the raw material powder of gained in step (3), in step (4), add water as former 10-14 times of material gross weight, decocts 25-55 minute, pours out medicinal liquid, and add water into raw material gross weight 5-8 times again, decocts 25- 55 minutes, merging three medicinal liquids, filter, being evaporated to 55-65 DEG C and surveying relative density is the clear paste of 1.05-1.15, standby;
(6) gained clear paste in step (5) is added the ethanol of 15% by volume, static 12-24 hour, fling to ethanol, after Filter, being further concentrated to 80-90 DEG C and surveying relative density is the extractum of 1.15-1.20, is placed in-5 to 0 DEG C freezing 48-72 hour, standby With;
(7) take raw material acesulfame potassium, sodium benzoate, essence are respectively crushed into 200-300 mesh, standby;
(8) gained extractum in step (6) being added pure water, amount of water is 6-9 times of its weight, stirs 15-in agitator tank 20 minutes, stand 4-8 hour, be stirred for 15-20 minute, make serosity flow into 325-360 mesh sieve hole reciprocating sieve while stirring and filter, Obtain filtrate, in filtrate, add acesulfame potassium and sodium benzoate after pulverizing, add essence after pulverizing after stirring 15-20 minute, then stir Mix 15-20 minute, finally under conditions of 4-8 DEG C, stand 12-24 hour, filter, by filtrate fill, sterilizing, must treat certainly The Chinese medicine preparation of antiperspirant night sweat.
Usage: oral, every day 2 times, each 15ml.
Traditional Chinese medicine composition for treating of the present invention observes spontaneous sweating patient 45 example, and clinical report is as follows:
1, physical data
Clinical observation spontaneous sweating patient 45 example, the maleest 25 examples, female 20 example, age 20-65 year, 42.5 years old mean age.
2, diagnostic criteria
Syndrome 1. lung is defended not solid: head, neck and chest are perspired constantly, after activity more so;Aversion to wind, usually easy catching a cold, fatigue and weakness, face Color is as violated with the whitest;Pale tongue, white and thin fur, weak pulse;
Syndrome 2. disharmony of nutrient QI with defensive QI: perspiration and aversion to wind tremble with fear, limbs are miserable, or have slight fever, or half body or local perspire;White and thin fur, moderate pulse;
Syndrome 3. hyperactivity of fire caused by deficiency of YIN: sleep middle head, neck, thoracic dorsal or panhidrosis, sweating and wake up, vexed fever of the body, thirsty and dry pharynx, red lip, Hectic fever in the afternoon, flushed cheeks;Red tongue, white and thin fur, thready and rapid pulse;
Syndrome 4. deficiency of both QI and YIN: spontaneous perspiration, night sweat, fear of cold, tired postemphasis, god is tired weak, dry throat and mouth;Red tongue, white and thin fur, arteries and veins Count accurately.
3, Therapeutic Method
Use Chinese medicine preparation of the present invention to treat, take Chinese medicine preparation of the present invention, every day 2 times, each 15ml, within 7 days, be a course for the treatment of.
4, efficacy evaluation
Cure: perspiration stopped, other transference cures;
Taking a turn for the better: sweating significantly reduces, other symptoms are improved;
Invalid: to perspire and other symptoms are the most unchanged.
5, therapeutic outcome
Clinical treatment spontaneous sweating is suffered from 45 example patients, cures 37 examples and accounts for 82.2%, and 5 examples that take a turn for the better account for 11.1%, and invalid 3 examples account for 6.7%, total effective rate is 93.3%.
6, model case
Case 1: man, 23 years old, patient's night sweating several months, perspires after falling asleep every day in a large number, and can drench time serious two-layer cotton pad;Sit up During feel lossless, drinking a lot of water, not without uncomfortable, dry pharynx, red lip, red tongue, white and thin fur, thready and rapid pulse;Take Chinese medicine preparation one of the present invention The individual course for the treatment of, patient symptom substantially alleviates, and takes again one course for the treatment of of Chinese medicine preparation of the present invention, and symptom is clearly better, and takes again this Two courses for the treatment of of bright Chinese medicine preparation, clinical cure.
Case 2: female, 37 years old, there is low grade fever, night sweat in patient, and body temperature often raises in afternoon, vexed fever of the body, thirsty and dry pharynx, lip Red, hectic fever in the afternoon, flushed cheeks, red tongue, white and thin fur, thready and rapid pulse, take one course for the treatment of of Chinese medicine preparation of the present invention, patient symptom is obvious Alleviating, take again one course for the treatment of of Chinese medicine preparation of the present invention, symptom is clearly better, and takes again two courses for the treatment of of Chinese medicine preparation of the present invention, Clinical cure.
Case 3: man, 49 years old, patient's power deficiency giddy was murky, p.prand cardiopalmus, moves at ordinary times and the most easily perspires, red tongue, tongue Bao Bai, thready and rapid pulse, take one course for the treatment of of Chinese medicine preparation of the present invention, patient symptom substantially alleviates, and takes again Chinese medicine preparation of the present invention One course for the treatment of, symptom is clearly better, and takes again two courses for the treatment of of Chinese medicine preparation of the present invention, clinical cure.
It should be pointed out that, the detailed description of the invention more representational example that is the present invention, it is clear that the skill of the present invention Art scheme is not limited to above-described embodiment, it is also possible to have many variations;Those of ordinary skill in the art, the most public with present invention institute What what that open or according to file written description was undoubted obtained, all it is considered as this patent scope of the claimed.

Claims (6)

1. the Chinese medicine preparation treating spontaneous sweating, it is characterised in that: it is made up of the raw material of following weight portion: Radix Astragali 120- 180 parts, Radix Ephedrae 10-70 part, Radix Pseudostellariae 70-130 part, Fructus Corni 70-130 part, Concha Ostreae (calcined) 150-210 part, Fructus Tritici Levis 120-180 Part, Ganoderma 30-90 part, Radix Paeoniae Alba 40-100 part, Folium Mori 40-100 part, Fructus Schisandrae Chinensis 20-80 part, Fructus Mori 20-80 part, Radix Rhodiolae 10-50 part, Semen Oroxyli 10-50 part, Radix Glycyrrhizae Preparata 10-50 part, Cortex Lycii 20-80 part, Radix Oryzae Glutinosae 70-130 part, Cortex Moutan 20-80 Part, Poria 20-80 part, Rhizoma Atractylodis Macrocephalae (parched) 20-80 part, acesulfame potassium 0.001-0.002 part, sodium benzoate 0.001-0.002 part, essence 0.001-0.0016 part.
The preparation method of a kind of Chinese medicine preparation treating spontaneous sweating the most according to claim 1, it is characterised in that: its system Standby step is:
(1) take raw material Concha Ostreae (calcined) and be ground into 100-180 mesh, standby;
(2) take raw material Ganoderma to pulverize, be ground into 260-300 mesh, standby;
(3) take the raw material Radix Astragali, Radix Ephedrae, Radix Pseudostellariae, Fructus Corni mixing, be ground into 50-80 mesh, obtain raw material powder, standby;
(4) take raw material Fructus Schisandrae Chinensis, Fructus Mori, Radix Rhodiolae, Semen Oroxyli, Radix Glycyrrhizae Preparata, Cortex Lycii, Radix Oryzae Glutinosae, Cortex Moutan, Poria, float Semen Tritici aestivi, Rhizoma Atractylodis Macrocephalae (parched), the Radix Paeoniae Alba, Folium Mori mixing, be ground into 50-80 mesh, obtain raw material powder, standby;
(5) add water 6-10 times into raw material total amount by the Ganoderma after pulverizing in the Concha Ostreae (calcined) after middle for step (1) pulverizing, step (2), Decocting 25-55 minute, pour out medicinal liquid, medicinal residues mix decoction with the raw material powder of gained in step (3), in step (4), add water as former 10-14 times of material gross weight, decocts 25-55 minute, pours out medicinal liquid, and add water into raw material gross weight 5-8 times again, decocts 25- 55 minutes, merging three medicinal liquids, filter, being evaporated to 55-65 DEG C and surveying relative density is the clear paste of 1.05-1.15, standby;
(6) gained clear paste in step (5) is added the ethanol of 15% by volume, static 12-24 hour, fling to ethanol, after Filter, being further concentrated to 80-90 DEG C and surveying relative density is the extractum of 1.15-1.20, is placed in-5 to 0 DEG C freezing 48-72 hour, standby With;
(7) take raw material acesulfame potassium, sodium benzoate, essence are respectively crushed into 200-300 mesh, standby;
(8) gained extractum in step (6) being added pure water, amount of water is 6-9 times of its weight, stirs 15-in agitator tank 20 minutes, stand 4-8 hour, be stirred for 15-20 minute, make serosity flow into 325-360 mesh sieve hole reciprocating sieve while stirring and filter, Obtain filtrate, in filtrate, add acesulfame potassium and sodium benzoate after pulverizing, add essence after pulverizing after stirring 15-20 minute, then stir Mix 15-20 minute, finally under conditions of 4-8 DEG C, stand 12-24 hour, filter, by filtrate fill, sterilizing, must treat certainly The Chinese medicine preparation of antiperspirant night sweat.
The preparation method of a kind of Chinese medicine preparation treating spontaneous sweating the most according to claim 2, it is characterised in that: its system Standby step is:
(1) take raw material Concha Ostreae (calcined) and be ground into 180 mesh, standby;
(2) take raw material Ganoderma to pulverize, be ground into 260 mesh, standby;
(3) take the raw material Radix Astragali, Radix Ephedrae, Radix Pseudostellariae, Fructus Corni mixing, be ground into 80 mesh, obtain raw material powder, standby;
(4) take raw material Fructus Schisandrae Chinensis, Fructus Mori, Radix Rhodiolae, Semen Oroxyli, Radix Glycyrrhizae Preparata, Cortex Lycii, Radix Oryzae Glutinosae, Cortex Moutan, Poria, float Semen Tritici aestivi, Rhizoma Atractylodis Macrocephalae (parched), the Radix Paeoniae Alba, Folium Mori mixing, be ground into 50 mesh, obtain raw material powder, standby;
(5) add water 10 times into raw material total amount by the Ganoderma after pulverizing in the Concha Ostreae (calcined) after middle for step (1) pulverizing, step (2), decocts Boiling 45 minutes, pour out medicinal liquid, medicinal residues mix decoction with the raw material powder of gained in step (3), in step (4), add water total into raw material 10 times of weight, decoct 45 minutes, pour out medicinal liquid, and add water into raw material gross weight 8 times again, decoct 35 minutes, merge three times Medicinal liquid, filters, and being evaporated to 65 DEG C and surveying relative density is the clear paste of 1.05, standby;
(6) gained clear paste in step (5) is added the ethanol of 15% by volume, static 12 hours, fling to ethanol, refilter, then Being concentrated into 80 DEG C and surveying relative density is the extractum of 1.15, is placed in-5 DEG C of freezings 48 hours, standby;
(7) take raw material acesulfame potassium, sodium benzoate, essence are respectively crushed into 300 mesh, standby;
(8) gained extractum in step (6) being added pure water, amount of water is 6 times of its weight, stirs 20 points in agitator tank Clock, stands 8 hours, is stirred for 20 minutes, makes serosity flow into 360 mesh sieve hole reciprocating sieves while stirring and filters, obtains filtrate, to filtrate Acesulfame potassium and sodium benzoate after middle addition pulverizing, add essence after pulverizing, be stirred for 20 minutes, finally 8 after stirring 20 minutes Stand 12 hours under conditions of DEG C, filter, by filtrate fill, sterilizing, the Chinese medicine preparation of spontaneous sweating must be treated.
A kind of Chinese medicine preparation treating spontaneous sweating the most according to claim 1, it is characterised in that: by following weight portion Raw material is made: the Radix Astragali 150 parts, Radix Ephedrae 40 parts, Radix Pseudostellariae 100 parts, Fructus Corni 100 parts, Concha Ostreae (calcined) 180 parts, Fructus Tritici Levis 150 parts, Ganoderma 60 parts, the Radix Paeoniae Alba 70 parts, 70 parts of Folium Mori, Fructus Schisandrae Chinensis 50 parts, Fructus Mori 50 parts, Radix Rhodiolae 30 parts, Semen Oroxyli 30 parts, Radix Glycyrrhizae Preparata 30 parts, Cortex Lycii 50 parts, Radix Oryzae Glutinosae 100 parts, Cortex Moutan 50 parts, 50 parts of Poria, Rhizoma Atractylodis Macrocephalae (parched) 50 parts, acesulfame potassium 0.0015 part, benzene Sodium formate 0.0015 part, 0.0013 part of essence.
A kind of Chinese medicine preparation treating spontaneous sweating the most according to claim 1, it is characterised in that: by following weight portion Raw material is made: the Radix Astragali 180 parts, Radix Ephedrae 70 parts, Radix Pseudostellariae 130 parts, Fructus Corni 130 parts, Concha Ostreae (calcined) 210 parts, Fructus Tritici Levis 180 parts, Ganoderma 90 parts, the Radix Paeoniae Alba 100 parts, 100 parts of Folium Mori, Fructus Schisandrae Chinensis 80 parts, Fructus Mori 80 parts, Radix Rhodiolae 50 parts, Semen Oroxyli 50 parts, process sweet Grass 50 parts, Cortex Lycii 80 parts, Radix Oryzae Glutinosae 130 parts, Cortex Moutan 80 parts, 80 parts of Poria, Rhizoma Atractylodis Macrocephalae (parched) 80 parts, acesulfame potassium 0.002 part, benzene Sodium formate 0.002 part, 0.0016 part of essence.
A kind of Chinese medicine preparation treating spontaneous sweating the most according to claim 1, it is characterised in that: by following weight portion Raw material is made: the Radix Astragali 120 parts, Radix Ephedrae 10 parts, Radix Pseudostellariae 70 parts, Fructus Corni 70 parts, Concha Ostreae (calcined) 150 parts, Fructus Tritici Levis 120 parts, spirit Sesame 30 parts, the Radix Paeoniae Alba 40 parts, 40 parts of Folium Mori, Fructus Schisandrae Chinensis 20 parts, Fructus Mori 20 parts, Radix Rhodiolae 10 parts, Semen Oroxyli 10 parts, Radix Glycyrrhizae Preparata 10 Part, Cortex Lycii 20 parts, Radix Oryzae Glutinosae 70 parts, Cortex Moutan 20 parts, 20 parts of Poria, Rhizoma Atractylodis Macrocephalae (parched) 20 parts, acesulfame potassium 0.001 part, benzoic acid 0.001 part of sodium, 0.001 part of essence.
CN201610992063.9A 2016-11-11 2016-11-11 A kind of Chinese medicine preparation treating spontaneous sweating and preparation method Pending CN106266739A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108450940A (en) * 2018-02-09 2018-08-28 甘孜州康定蓝生态科技有限责任公司 Lower hyperlipidemia, hypertension, hyperglycemia, radioresistance tumour, the health products and preparation method for improving immunity
CN114887001A (en) * 2022-07-01 2022-08-12 韩旭 Traditional Chinese medicine composition for treating hyperhidrosis and decoction preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435837A (en) * 2014-11-29 2015-03-25 邹士东 Pharmaceutical composition for treating spontaneous perspiration and night sweat

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435837A (en) * 2014-11-29 2015-03-25 邹士东 Pharmaceutical composition for treating spontaneous perspiration and night sweat

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108450940A (en) * 2018-02-09 2018-08-28 甘孜州康定蓝生态科技有限责任公司 Lower hyperlipidemia, hypertension, hyperglycemia, radioresistance tumour, the health products and preparation method for improving immunity
CN114887001A (en) * 2022-07-01 2022-08-12 韩旭 Traditional Chinese medicine composition for treating hyperhidrosis and decoction preparation method thereof
CN114887001B (en) * 2022-07-01 2023-04-18 韩旭 Traditional Chinese medicine composition for treating hyperhidrosis and decoction preparation method thereof

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