CN105213890A - A kind of Chinese medicine oral liquid and preparation method for the treatment of spontaneous perspiration hyperhidrosis - Google Patents
A kind of Chinese medicine oral liquid and preparation method for the treatment of spontaneous perspiration hyperhidrosis Download PDFInfo
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Abstract
The present invention discloses a kind of Chinese medicine oral liquid and preparation method for the treatment of spontaneous perspiration hyperhidrosis, is made up of following raw material: Radix Astragali 6-10 part, Fructus Schisandrae Chinensis 13-17 part, Semen Coicis 38-42 part, Fructus Corni 38-42 part, Concha Ostreae (calcined) 6-10 part, Radix Ephedrae 8-12 part, Radix Ginseng 13-17 part, Carapax et Plastrum Testudinis 28-32 part, Ramulus Cinnamomi 3-7 part, Rhizoma Atractylodis Macrocephalae 18-22 part, Radix Puerariae 38-42 part, Radix Paeoniae Alba 28-32 part, Radix Ophiopogonis 18-22 part, Radix Glycyrrhizae Preparata 6-10 part.The present invention has strengthens the spleen and stomach, YANG hyperactivity suppressing nourishing YIN, restrains effect that is astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, and be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid for the treatment of spontaneous perspiration hyperhidrosis, belong to the field of Chinese medicines.
Background technology
Spontaneous perspiration hyperhidrosis is not because of tired movable, not because of sky heat and warm performance of taking factors such as dispersing medicine and natural sweating of wearing the clothes, many because of disharmony of nutrient QI with defensive QI, extreme heat in YANG MING, summer-heat is felt frustrated the moon, deficiency of vital energy yang deficiency etc. causes, be found in diseases caused by exogenous pathogenic factor six climate exopathogens or miscellaneous diseases caused by endogenous pathogens, the former mostly is excess syndrome, the latter mostly is deficiency syndrome, daytime is not because of fatigue, or without obvious inducement constantly antiperspirant go out, easily benefit symptom very, go out also known as spontaneous perspiration hyperhidrosis, many because of disharmony of nutrient QI with defensive QI, extreme heat in YANG MING, summer-heat is felt frustrated the moon, deficiency of vital energy yang deficiency etc. causes, be found in diseases caused by exogenous pathogenic factor six climate exopathogens or miscellaneous diseases caused by endogenous pathogens, the former mostly is excess syndrome, the latter mostly is deficiency syndrome, the western medical treatment Main Means taked this disease at present takes tranquilizer and low dose of antianxiety drugs is effective to the hyperhidrosis of emotionality spontaneous perspiration, and take too many harmful unhelpful.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine oral liquid for the treatment of spontaneous perspiration hyperhidrosis, it has strengthens the spleen and stomach, YANG hyperactivity suppressing nourishing YIN, restrains effect that is astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine oral liquid for spontaneous perspiration hyperhidrosis, be made up of following raw material: Radix Astragali 6-10 part, Fructus Schisandrae Chinensis 13-17 part, Semen Coicis 38-42 part, Fructus Corni 38-42 part, Concha Ostreae (calcined) 6-10 part, Radix Ephedrae 8-12 part, Radix Ginseng 13-17 part, Carapax et Plastrum Testudinis 28-32 part, Ramulus Cinnamomi 3-7 part, Rhizoma Atractylodis Macrocephalae 18-22 part, Radix Puerariae 38-42 part, Radix Paeoniae Alba 28-32 part, Radix Ophiopogonis 18-22 part, Radix Glycyrrhizae Preparata 6-10 part.
Preferably, each parts by weight of raw materials is: the Radix Astragali 8 parts, Fructus Schisandrae Chinensis 15 parts, Semen Coicis 40 parts, Fructus Corni 40 parts, Concha Ostreae (calcined) 8 parts, Radix Ephedrae 10 parts, Radix Ginseng 15 parts, Carapax et Plastrum Testudinis 30 parts, Ramulus Cinnamomi 5 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Puerariae 40 parts, the Radix Paeoniae Alba 30 parts, Radix Ophiopogonis 20 parts, Radix Glycyrrhizae Preparata 8 parts.
Pharmacological action:
The Radix Astragali: nature and flavor with return through: sweet, temperature; Return lung, spleen channel, function with cure mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation; Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, the hyperhidrosis of exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Fructus Schisandrae Chinensis: nature and flavor with return through: sour, sweet, temperature; Return lung, the heart, kidney channel, function with cure mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming; For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration hyperhidrosis, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Semen Coicis: nature and flavor with return through: sweet, light, cool; Return spleen, stomach, lung meridian, function with cure mainly: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, heat clearing away row dense; For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
Fructus Corni: nature and flavor with return through: sour, puckery, tepor; Return liver, kidney channel, function with cure mainly: liver and kidney tonifying, essence astringing and desertion stemming; For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed; Interior-heat is quenched one's thirst.
Concha Ostreae (calcined): nature and flavor with return through: salty, be slightly cold; Return liver, gallbladder, kidney channel, function with cure mainly: tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving; For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule ， mass in the abdomen mass in the abdomen; Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating; For spontaneous perspiration hyperhidrosis night sweat, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Radix Ephedrae: nature and flavor with return through: sweet, flat; GUIXIN, lung meridian, function with cure mainly: hidroschesis; For spontaneous perspiration hyperhidrosis, night sweat.
Radix Ginseng: nature and flavor: sweet, flat, micro-hardship, slightly cold; There is the function of tonifying QI to produce body fluid, the mind calming and mentality promoting, it can promote the production of body fluid, yin nourishing and clearind deficient heat; Various processing beyond Radix Ginseng Rubra, as Radix Ginseng, white sugar ginseng, suncured white ginseng root etc., are generally referred to as Radix Ginseng.
Carapax et Plastrum Testudinis: meridian distribution of property and flavor: salty sweet is flat; Enter the heart, spleen, liver three warp; Effect: YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone; Cure mainly: control deficiency of kidney yin, hectic fever due to YIN-deficiency consumptive fever, spit blood, epistaxis, chronic cough, seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.
Ramulus Cinnamomi: nature and flavor with return through acrid, sweet, warm; GUIXIN, lung, urinary bladder channel, function with cure mainly: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins; For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
The Rhizoma Atractylodis Macrocephalae: nature and flavor with return through: bitter, sweet, temperature; Return spleen, stomach warp, function with cure mainly: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive; For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration hyperhidrosis, frequent fetal movement; Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive; For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
Radix Puerariae: nature and flavor with return through: sweet, pungent, cool; Return spleen, stomach warp; Function with cure mainly: expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, yang invigorating antidiarrheal; For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
The Radix Paeoniae Alba: nature and flavor with return through: bitter, sour, be slightly cold; Return liver, spleen channel, function with cure mainly: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating; Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration hyperhidrosis, night sweat.
Radix Ophiopogonis: nature and flavor with return through: sweet, micro-hardship, is slightly cold; GUIXIN, lung, stomach warp, function with cure mainly: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire; For dryness of the lung dry cough; Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
Radix Glycyrrhizae Preparata: meridian distribution of property and flavor: sweet is flat; GUIXIN, lung, spleen, stomach warp; Function cures mainly: spleen reinforcing stomach function regulating, Yiqi and vein recovery; For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse, can separate Radix Aconiti Lateralis Preparata poison, zhigancao decoction has benefiting qi and nourishing yin, and activate yang multiple arteries and veins therapeutic efficiency.
Another technical problem to be solved by this invention is to provide a kind of preparation method preparing above-mentioned Chinese medicine oral liquid.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
Treat a preparation method for the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis, be prepared from by following methods:
(1) get the raw material Radix Astragali, Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(2) get raw material Fructus Schisandrae Chinensis, Semen Coicis, Fructus Corni cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(3) get raw material Concha Ostreae (calcined), Carapax et Plastrum Testudinis cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(5) gained filtrate in step (4) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;
(6) filter in step (5) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;
(7) gained filtrate in step (6) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;
(8) gained clear paste in step (7) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis.
Preferably, a kind of preparation method for the treatment of the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis, is prepared from by following methods:
(1) get the raw material Radix Astragali, Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30 mesh sieves, for subsequent use;
(2) get raw material Fructus Schisandrae Chinensis, Semen Coicis, Fructus Corni cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30 mesh sieves, for subsequent use;
(3) get raw material Concha Ostreae (calcined), Carapax et Plastrum Testudinis cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(4) Radix Astragali after pulverizing in step (1), Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata are added the soak by water 2 hours of above-mentioned raw materials weight and 12 times, release medicinal liquid; Fructus Schisandrae Chinensis after pulverizing in step (2), Semen Coicis, Fructus Corni are added the soak by water 2 hours of above-mentioned raw materials weight and 12 times, release medicinal liquid; Concha Ostreae (calcined) after pulverizing in step (3), Carapax et Plastrum Testudinis are added the water of above-mentioned raw materials weight and 13 times, decocts 2.5 hours, releasing medicinal liquid; Three medicinal residues add the soak by water 1.5 hours of its weight 8 times after merging, release medicinal liquid; Merge the medicinal liquid decocted for four times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is added the ethanol of 95% of filtrate weight 1.5 times, leave standstill 24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane aperture of described leaf filter is 0.8 μm, in the process of filtering, pressure limit is 0.15MPa, face discharge is 1.5T/h, obtains filtrate, for subsequent use;
(6) filter in step (5) in gained filtrate feeding leaf filter, the filter membrane aperture of described leaf filter is 0.8 μm, and in the process of filtering, pressure limit is 0.15MPa, and face discharge is 0.8T/h, obtains filtrate, for subsequent use;
(7) gained filtrate in step (6) is sent into traditional Chinese drug inspissation machine, when being evaporated to 60 DEG C in thickener, the clear paste of relative density 1.05, obtains clear paste, for subsequent use;
(8) gained clear paste in step (7) is statically placed in 24 hours under the condition of 6 DEG C, by sodium hydroxide solution adjust ph to 6.5, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis.
Beneficial effect: the present invention has strengthens the spleen and stomach, YANG hyperactivity suppressing nourishing YIN, restrains effect that is astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, and be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
The present invention adopts pure Chinese medicine to be raw material, according to pathogenic factor and the Clinical symptoms of spontaneous perspiration hyperhidrosis, under instruction of Chinese Medicine theory, carry out prescription be prepared from the basis not being raw-material activity, show through clinical efficacy, this medicine has definite curative effect to spontaneous perspiration hyperhidrosis, is the ideal treatment medication of a kind of spontaneous perspiration hyperhidrosis patient.
Model case
Case 1: Mr. Han, 23 years old, medical history: head and neck dripping sweat is more than, obstinate, patient's head and neck spontaneous perspiration hyperhidrosis 3 years, if a little one move, namely sweating like rain, once repeatedly hospitalize, poor effect, turns Chinese traditional treatment, takes Drug therapy of the present invention 4 days diseases and becomes to fully recovering, take medicine of the present invention patient's above-mentioned symptom disappearance after 7 days, follow up a case by regular visits to 1 year without recurrence.
Case 2: Mr. Shao, 30 years old, medical history: causeless spontaneous perspiration hyperhidrosis half a year, no matter movable or rest forehead and the hyperhidrosis of cervical region spontaneous perspiration goes out, malaise, hospitalize, poor effect, turn Chinese traditional treatment, take Drug therapy of the present invention 7 days diseases to become to fully recovering, take medicine of the present invention patient's above-mentioned symptom disappearance after 14 days, follow up a case by regular visits to 1 year without recurrence.
Case 3: Mrs Hua, 25 years old, medical history: morbidity for many years, is easily perspired, activity and sweating are wet clothing a little, easy catching a cold, and aversion to wind, is afraid of cold, summer, To Be Protected from Heat, takes Drug therapy of the present invention 7 days diseases and become to fully recovering, take medicine of the present invention patient's above-mentioned symptom disappearance after 21 days, follow up a case by regular visits to 1 year without recurrence.
Case 4: Mr. Zhuan, 38 years old, medical history: main suit's spontaneous perspiration hyperhidrosis 1 year, all over seeking medical advice and not imitating, Shi Zihan hyperhidrosis, completely wet, within one day, change clothes several times, as long as one move a little, namely sweating like rain, take Drug therapy of the present invention 7 days diseases to become to fully recovering, take medicine of the present invention patient's above-mentioned symptom disappearance after 14 days, follow up a case by regular visits to 1 year without recurrence.
Case 5: Mr. Tian, 30 years old, medical history: palm, oxter, sole hyperhidrosis, aggravation of perspiring time nervous, took Drug therapy of the present invention 7 days diseases and becomes to fully recovering, take medicine of the present invention patient's above-mentioned symptom disappearance after 14 days, follow up a case by regular visits to 1 year without recurrence.
Case 6: Mrs Yi, 55 years old, medical history: started before 2 years, sensation is generated heat for a moment, back dripping sweat, the cold foot of sweating back is cool, and not easily stops, take Drug therapy of the present invention 7 days diseases to become to fully recovering, take medicine of the present invention patient's above-mentioned symptom disappearance after 21 days, follow up a case by regular visits to 1 year without recurrence.
Clinical data
Physical data: this Chinese medicine composition be applied to clinical observation case 36 example, wherein man 26 example, female 10 example, age 15-58 year.
Diagnostic criteria: (1) not because of external environment impact, the symptom in women's head-ornaments, neck breast or the hyperhidrosis of extremity panhidrosis person spontaneous perspiration: Qi, (2) day sweating Qi, dynamic then benefit very spontaneous perspiration hyperhidrosis.
Therapeutic Method: take oral liquid of the present invention, every day 2 times, each 40ml 7 days was 1 course for the treatment of.
Curative effect determinate standard: 1) fully recover: sings and symptoms disappears or substantially disappears; 2) take a turn for the better: sings and symptoms major part takes a turn for the better, and spontaneous perspiration hyperhidrosis cardinal symptom obviously alleviates, nervous weak, micro-perspiration sometimes after activity; 3) invalid; Sings and symptoms is all not improved, and symptom is as front.
Therapeutic effect: by this side treatment spontaneous perspiration hyperhidrosis case 36 example, wherein clinical recovery 32 example, take a turn for the better 4 examples, and invalid 0 example, total effective rate is 100%.
Detailed description of the invention
Embodiment 1
The present invention treats the preparation of spontaneous perspiration hyperhidrosis Chinese medicine oral liquid, and the weight portion of each raw material is: the Radix Astragali 10 parts, Fructus Schisandrae Chinensis 17 parts, Semen Coicis 42 parts, Fructus Corni 42 parts, Concha Ostreae (calcined) 10 parts, Radix Ephedrae 12 parts, Radix Ginseng 17 parts, Carapax et Plastrum Testudinis 32 parts, Ramulus Cinnamomi 7 parts, the Rhizoma Atractylodis Macrocephalae 22 parts, Radix Puerariae 42 parts, the Radix Paeoniae Alba 32 parts, Radix Ophiopogonis 22 parts, Radix Glycyrrhizae Preparata 10 parts;
Be prepared from by following methods:
(1) get the raw material Radix Astragali, Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(2) get raw material Fructus Schisandrae Chinensis, Semen Coicis, Fructus Corni cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(3) get raw material Concha Ostreae (calcined), Carapax et Plastrum Testudinis cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(4) Radix Astragali after pulverizing in step (1), Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, release medicinal liquid; Fructus Schisandrae Chinensis after pulverizing in step (2), Semen Coicis, Fructus Corni are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, releases medicinal liquid; Concha Ostreae (calcined) after pulverizing in step (3), Carapax et Plastrum Testudinis are added above-mentioned raw materials weight and 8-13 water doubly, decocts 1.5-3.5 hour, release medicinal liquid; Add its weight 6-8 soak by water 1.5-2.5 hour doubly after three times medicinal residues merge, release medicinal liquid; Merge the medicinal liquid decocted for four times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;
(6) filter in step (5) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;
(7) gained filtrate in step (6) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;
(8) gained clear paste in step (7) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis.
Usage: oral, every day 2 times, each 40ml.
Embodiment 2
The present invention treats the preparation of spontaneous perspiration hyperhidrosis Chinese medicine oral liquid, and the weight portion of each raw material is: the Radix Astragali 8 parts, Fructus Schisandrae Chinensis 15 parts, Semen Coicis 40 parts, Fructus Corni 40 parts, Concha Ostreae (calcined) 8 parts, Radix Ephedrae 10 parts, Radix Ginseng 15 parts, Carapax et Plastrum Testudinis 30 parts, Ramulus Cinnamomi 5 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Puerariae 40 parts, the Radix Paeoniae Alba 30 parts, Radix Ophiopogonis 20 parts, Radix Glycyrrhizae Preparata 8 parts;
Be prepared from by following methods:
(1) get the raw material Radix Astragali, Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(2) get raw material Fructus Schisandrae Chinensis, Semen Coicis, Fructus Corni cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(3) get raw material Concha Ostreae (calcined), Carapax et Plastrum Testudinis cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(4) Radix Astragali after pulverizing in step (1), Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, release medicinal liquid; Fructus Schisandrae Chinensis after pulverizing in step (2), Semen Coicis, Fructus Corni are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, releases medicinal liquid; Concha Ostreae (calcined) after pulverizing in step (3), Carapax et Plastrum Testudinis are added above-mentioned raw materials weight and 8-13 water doubly, decocts 1.5-3.5 hour, release medicinal liquid; Add its weight 6-8 soak by water 1.5-2.5 hour doubly after three times medicinal residues merge, release medicinal liquid; Merge the medicinal liquid decocted for four times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;
(6) filter in step (5) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;
(7) gained filtrate in step (6) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;
(8) gained clear paste in step (7) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis.
Usage: oral, every day 2 times, each 40ml.
Embodiment 3
The present invention treats the preparation of spontaneous perspiration hyperhidrosis Chinese medicine oral liquid, and the weight portion of each raw material is: the Radix Astragali 6 parts, Fructus Schisandrae Chinensis 13 parts, Semen Coicis 38 parts, Fructus Corni 38 parts, Concha Ostreae (calcined) 6 parts, Radix Ephedrae 8 parts, Radix Ginseng 13 parts, Carapax et Plastrum Testudinis 28 parts, Ramulus Cinnamomi 3 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Radix Puerariae 38 parts, the Radix Paeoniae Alba 28 parts, Radix Ophiopogonis 18 parts, Radix Glycyrrhizae Preparata 6 parts;
Be prepared from by following methods:
(1) get the raw material Radix Astragali, Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(2) get raw material Fructus Schisandrae Chinensis, Semen Coicis, Fructus Corni cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(3) get raw material Concha Ostreae (calcined), Carapax et Plastrum Testudinis cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(4) Radix Astragali after pulverizing in step (1), Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, release medicinal liquid; Fructus Schisandrae Chinensis after pulverizing in step (2), Semen Coicis, Fructus Corni are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, releases medicinal liquid; Concha Ostreae (calcined) after pulverizing in step (3), Carapax et Plastrum Testudinis are added above-mentioned raw materials weight and 8-13 water doubly, decocts 1.5-3.5 hour, release medicinal liquid; Add its weight 6-8 soak by water 1.5-2.5 hour doubly after three times medicinal residues merge, release medicinal liquid; Merge the medicinal liquid decocted for four times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;
(6) filter in step (5) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;
(7) gained filtrate in step (6) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;
(8) gained clear paste in step (7) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis.
Usage: oral, every day 2 times, each 40ml.
Claims (6)
1. treat a Chinese medicine oral liquid for spontaneous perspiration hyperhidrosis, it is characterized in that: be made up of following raw material: Radix Astragali 6-10 part, Fructus Schisandrae Chinensis 13-17 part, Semen Coicis 38-42 part, Fructus Corni 38-42 part, Concha Ostreae (calcined) 6-10 part, Radix Ephedrae 8-12 part, Radix Ginseng 13-17 part, Carapax et Plastrum Testudinis 28-32 part, Ramulus Cinnamomi 3-7 part, Rhizoma Atractylodis Macrocephalae 18-22 part, Radix Puerariae 38-42 part, Radix Paeoniae Alba 28-32 part, Radix Ophiopogonis 18-22 part, Radix Glycyrrhizae Preparata 6-10 part.
2. a kind of Chinese medicine oral liquid for the treatment of spontaneous perspiration hyperhidrosis according to claim 1, is characterized in that: the weight portion of each raw material is: the Radix Astragali 8 parts, Fructus Schisandrae Chinensis 15 parts, Semen Coicis 40 parts, Fructus Corni 40 parts, Concha Ostreae (calcined) 8 parts, Radix Ephedrae 10 parts, Radix Ginseng 15 parts, Carapax et Plastrum Testudinis 30 parts, Ramulus Cinnamomi 5 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Puerariae 40 parts, the Radix Paeoniae Alba 30 parts, Radix Ophiopogonis 20 parts, Radix Glycyrrhizae Preparata 8 parts.
3. a kind of Chinese medicine oral liquid for the treatment of spontaneous perspiration hyperhidrosis according to claim 1, is characterized in that: the weight portion of each raw material is: the Radix Astragali 10 parts, Fructus Schisandrae Chinensis 17 parts, Semen Coicis 42 parts, Fructus Corni 42 parts, Concha Ostreae (calcined) 10 parts, Radix Ephedrae 12 parts, Radix Ginseng 17 parts, Carapax et Plastrum Testudinis 32 parts, Ramulus Cinnamomi 7 parts, the Rhizoma Atractylodis Macrocephalae 22 parts, Radix Puerariae 42 parts, the Radix Paeoniae Alba 32 parts, Radix Ophiopogonis 22 parts, Radix Glycyrrhizae Preparata 10 parts.
4. a kind of Chinese medicine oral liquid for the treatment of spontaneous perspiration hyperhidrosis according to claim 1, is characterized in that: the weight portion of each raw material is: the Radix Astragali 6 parts, Fructus Schisandrae Chinensis 13 parts, Semen Coicis 38 parts, Fructus Corni 38 parts, Concha Ostreae (calcined) 6 parts, Radix Ephedrae 8 parts, Radix Ginseng 13 parts, Carapax et Plastrum Testudinis 28 parts, Ramulus Cinnamomi 3 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Radix Puerariae 38 parts, the Radix Paeoniae Alba 28 parts, Radix Ophiopogonis 18 parts, Radix Glycyrrhizae Preparata 6 parts.
5. a kind of preparation method for the treatment of the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) get the raw material Radix Astragali, Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(2) get raw material Fructus Schisandrae Chinensis, Semen Coicis, Fructus Corni cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(3) get raw material Concha Ostreae (calcined), Carapax et Plastrum Testudinis cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(4) Radix Astragali after pulverizing in step (1), Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, release medicinal liquid; Fructus Schisandrae Chinensis after pulverizing in step (2), Semen Coicis, Fructus Corni are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, releases medicinal liquid; Concha Ostreae (calcined) after pulverizing in step (3), Carapax et Plastrum Testudinis are added above-mentioned raw materials weight and 8-13 water doubly, decocts 1.5-3.5 hour, release medicinal liquid; Add its weight 6-8 soak by water 1.5-2.5 hour doubly after three times medicinal residues merge, release medicinal liquid; Merge the medicinal liquid decocted for four times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;
(6) filter in step (5) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;
(7) gained filtrate in step (6) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;
(8) gained clear paste in step (7) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis.
6. a kind of preparation method for the treatment of the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) get the raw material Radix Astragali, Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30 mesh sieves, for subsequent use;
(2) get raw material Fructus Schisandrae Chinensis, Semen Coicis, Fructus Corni cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30 mesh sieves, for subsequent use;
(3) get raw material Concha Ostreae (calcined), Carapax et Plastrum Testudinis cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;
(4) Radix Astragali after pulverizing in step (1), Radix Ephedrae, Radix Ginseng, Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae, Radix Puerariae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata are added the soak by water 2 hours of above-mentioned raw materials weight and 12 times, release medicinal liquid; Fructus Schisandrae Chinensis after pulverizing in step (2), Semen Coicis, Fructus Corni are added the soak by water 2 hours of above-mentioned raw materials weight and 12 times, release medicinal liquid; Concha Ostreae (calcined) after pulverizing in step (3), Carapax et Plastrum Testudinis are added the water of above-mentioned raw materials weight and 13 times, decocts 2.5 hours, releasing medicinal liquid; Three medicinal residues add the soak by water 1.5 hours of its weight 8 times after merging, release medicinal liquid; Merge the medicinal liquid decocted for four times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is added the ethanol of 95% of filtrate weight 1.5 times, leave standstill 24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane aperture of described leaf filter is 0.8 μm, in the process of filtering, pressure limit is 0.15MPa, face discharge is 1.5T/h, obtains filtrate, for subsequent use;
(6) filter in step (5) in gained filtrate feeding leaf filter, the filter membrane aperture of described leaf filter is 0.8 μm, and in the process of filtering, pressure limit is 0.15MPa, and face discharge is 0.8T/h, obtains filtrate, for subsequent use;
(7) gained filtrate in step (6) is sent into traditional Chinese drug inspissation machine, when being evaporated to 60 DEG C in thickener, the clear paste of relative density 1.05, obtains clear paste, for subsequent use;
(8) gained clear paste in step (7) is statically placed in 24 hours under the condition of 6 DEG C, by sodium hydroxide solution adjust ph to 6.5, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid of spontaneous perspiration hyperhidrosis.
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