CN105079338A - Skin brightening drug - Google Patents
Skin brightening drug Download PDFInfo
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- CN105079338A CN105079338A CN201510601676.0A CN201510601676A CN105079338A CN 105079338 A CN105079338 A CN 105079338A CN 201510601676 A CN201510601676 A CN 201510601676A CN 105079338 A CN105079338 A CN 105079338A
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Abstract
The invention belongs to the field of traditional Chinese medicine preparations, and particularly provides a skin brightening drug which is prepared from the following raw materials: 28 parts of cassytha filiformis L., 25 parts of aconitum bullatifolium levl., 18 parts of lysimachia fortunei maxim., 20 parts of salomonia cantoniensis lour, 15 parts of radix angelicae, 20 parts of radix paeoniae alba, 20 parts of aloe, 25 parts of herba ecliptae, 25 parts of ginseng, 20 parts of radix lithospermi, 15 parts of herba hedyotis, 18 parts of tartary buckwheat, 15 parts of angelica sinensis, 20 parts of ligusticum wallichii, 15 parts of dandelion, and 5 parts of liquorice. The skin brightening drug can be used for brightening skin.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of skin whitening medicine and its preparation method and application.
Background technology
Everybody has a love of beauty, and the women of many youths often uses cosmetics to carry out maintaining to skin, makes it seem beautiful and young, thus more confident.From ancient times to the present, Chinese crude drug is widely used in skin whitening, soft skin, prevents chapped skin, regulates fat secretion, treats freckle and comedo etc., is bursting to and develops the needs that more medicines of skin whitening safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of skin whitening medicine.
In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of skin whitening medicine, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba Casythae Filiformis 28 parts, Radix Aconiti Heterotrichi 25, large Herba Hyperici Japonici 18 parts, Herba Salomoniae Cantoniensis 20 parts, the Radix Angelicae Dahuricae 15 parts, the Radix Paeoniae Alba 20 parts, Aloe 20 parts, Herba Ecliptae 25 parts, Radix Ginseng 25 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Herba Hedyotidis Diffusae 15 parts, Radix Et Rhizoma Fagopyri Tatarici 18 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 20 parts, Herba Taraxaci 15 parts, 5 parts, Radix Glycyrrhizae.
Described skin whitening medicine, dosage form is pharmaceutically acceptable granule, tablet, capsule.
Described skin whitening medicine, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The application in skin whitening medicine prepared by described skin whitening medicine.
Herba Casythae Filiformis is the herb of canella dodder laurel.Latin name: CassythafiliformisL. clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body.Cure mainly cold, fever, pyretic stranguria, stranguria caused by urinary stone, jaundice due to damp-heat, have loose bowels, dysentery, spitting of blood, epistaxis, wind-fire acute conjunctivitis, traumatic injury, traumatic hemorrhage, skin infection festers, burn due to hot liquid or fire, scabies tinea leprosy.
Radix Aconiti Heterotrichi is Ranunculaceae aconitum plant wrinkle leaf Aconitum carmichjaelii Debx. AconitumbullatifoliumLevl., is used as medicine with tuber.Autumn, winter gather, and remove fibrous root.Expelling wind and cold, activating collaterals to relieve pain.For rheumatic arthritis, lumbar muscle strain, soft tissue contusion, articular sprain, intercostal neuralgia.
Large Herba Hyperici Japonici is Primulaceae Lysimachia plant Arisaema balansae Engl. Herba lysimachiae capillipedis LysimachiafortuneiMaxim., with all herbal medicine.Summer, autumn gather, clean, dry, cutting or binding for subsequent use.Clearing away heat-damp and promoting diuresis, promoting blood flow to regulate menstruation.For flu, cough spitting of blood, enteritis, dysentery, hepatitis, infantile malnutrition, malaria, rheumatic arthritis, dysmenorrhea, amenorrhea, leucorrhea; Mastitis, conjunctivitis, venom, traumatic injury.
Herba Salomoniae Cantoniensis, Classification system SalomoniacantoniensisLour is the herb of milk wort tooth fruit grass.Removing toxic substances, pain relieving, removing nebula.Control innominate toxic swelling, toothache, look unfamiliar tunica albuginea.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: traditional Chinese medical science whitening, under instruction of Chinese Medicine theory, uses Chinese medicine conditioning viscera, Yin Yang balancing, to reach the object of whitening, by the method for activating blood and removing stasis Method, depressed liver-energy dispersing and QI regulating method, temperature male wind-supplying kidney method.Herba Casythae Filiformis of the present invention 28 parts, Radix Aconiti Heterotrichi 25, large Herba Hyperici Japonici 18 parts, Herba Salomoniae Cantoniensis 20 parts, the Radix Angelicae Dahuricae 15 parts, the Radix Paeoniae Alba 20 parts, Aloe 20 parts, Herba Ecliptae 25 parts, Radix Ginseng 25 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Herba Hedyotidis Diffusae 15 parts, Radix Et Rhizoma Fagopyri Tatarici 18 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 20 parts, Herba Taraxaci 15 parts, 5 parts, Radix Glycyrrhizae are monarch drug, Margarita powder, Radix Achyranthis Bidentatae, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, Semen Coicis blood circulation promoting and blood stasis dispelling are ministerial drug, Radix Glycyrrhizae is adjuvant, heat-clearing and toxic substances removing, dampness, blood circulation promoting and blood stasis dispelling, the mutual compatibility of full side, skin lightening effects is obvious.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Herba Casythae Filiformis 28g, Radix Aconiti Heterotrichi 25, large Herba Hyperici Japonici 18g, Herba Salomoniae Cantoniensis 20g, Radix Angelicae Dahuricae 15g, Radix Paeoniae Alba 20g, Aloe 20g, Herba Ecliptae 25g, Radix Ginseng 25g, Radix Arnebiae (Radix Lithospermi) 20g, Herba Hedyotidis Diffusae 15g, Radix Et Rhizoma Fagopyri Tatarici 18g, Radix Angelicae Sinensis 15g, Rhizoma Chuanxiong 20g, Herba Taraxaci 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Herba Casythae Filiformis 28g, Radix Aconiti Heterotrichi 25, large Herba Hyperici Japonici 18g, Herba Salomoniae Cantoniensis 20g, Radix Angelicae Dahuricae 15g, Radix Paeoniae Alba 20g, Aloe 20g, Herba Ecliptae 25g, Radix Ginseng 25g, Radix Arnebiae (Radix Lithospermi) 20g, Herba Hedyotidis Diffusae 15g, Radix Et Rhizoma Fagopyri Tatarici 18g, Radix Angelicae Sinensis 15g, Rhizoma Chuanxiong 20g, Herba Taraxaci 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get Herba Casythae Filiformis 28g, Radix Aconiti Heterotrichi 25, large Herba Hyperici Japonici 18g, Herba Salomoniae Cantoniensis 20g, Radix Angelicae Dahuricae 15g, Radix Paeoniae Alba 20g, Aloe 20g, Herba Ecliptae 25g, Radix Ginseng 25g, Radix Arnebiae (Radix Lithospermi) 20g, Herba Hedyotidis Diffusae 15g, Radix Et Rhizoma Fagopyri Tatarici 18g, Radix Angelicae Sinensis 15g, Rhizoma Chuanxiong 20g, Herba Taraxaci 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, fill, make capsule.
4, pharmaceutical preparation skin whitening of the present invention clinical research
4.1 general data: this pharmaceutical preparation is applied to clinical observation case 60 example, 17 ~ 40 years old age.The shortest person of the course of disease 4 months, most elder reaches 1 year.
4.2 diagnostic criterias:: face is obscure, matt, locally have spot or pigmentation, some position wrinkle is obvious.
4.3 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within five days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule five days is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.4 criterions of therapeutical effect: recovery from illness: melanin disappears and reaches more than 90%, take front and take the comparison of rear computer local skin photo, the colour of skin promotes, successful, and skin has significantly moist smooth feeling; Effective: melanin disappears more than 50%, take front and take the comparison of rear computer local skin photo, the colour of skin promotes, and effect is comparatively obvious, and skin is comparatively moist smooth; (3) invalid: unchanged before and after treatment.
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 30 | 15 | 12 | 3 | 90 |
| Blank group | 30 | 1 | 2 | 27 | 10 |
Visible, the medicine that the present invention obtains can safe and effective skin whitening, and has no side effect.
Claims (4)
1. a skin whitening medicine, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba Casythae Filiformis 28 parts, Radix Aconiti Heterotrichi 25, large Herba Hyperici Japonici 18 parts, Herba Salomoniae Cantoniensis 20 parts, the Radix Angelicae Dahuricae 15 parts, the Radix Paeoniae Alba 20 parts, Aloe 20 parts, Herba Ecliptae 25 parts, Radix Ginseng 25 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Herba Hedyotidis Diffusae 15 parts, Radix Et Rhizoma Fagopyri Tatarici 18 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Chuanxiong 20 parts, Herba Taraxaci 15 parts, 5 parts, Radix Glycyrrhizae.
2. skin whitening medicine as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. skin whitening medicine as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. the application of skin whitening medicine in skin whitening medicine according to claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510601676.0A CN105079338A (en) | 2015-09-19 | 2015-09-19 | Skin brightening drug |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510601676.0A CN105079338A (en) | 2015-09-19 | 2015-09-19 | Skin brightening drug |
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| CN105079338A true CN105079338A (en) | 2015-11-25 |
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| CN201510601676.0A Withdrawn CN105079338A (en) | 2015-09-19 | 2015-09-19 | Skin brightening drug |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804163A (en) * | 2010-04-21 | 2010-08-18 | 黄泳葛 | Special acne removing medicine and treatment method |
| CN104434743A (en) * | 2013-09-17 | 2015-03-25 | 上海誉盛科贸有限公司 | Pure plant component cosmetic and manufacturing method thereof |
| CN104771744A (en) * | 2015-04-27 | 2015-07-15 | 臧孝国 | Traditional Chinese medicine composition for treating urticaria |
| CN104984160A (en) * | 2015-06-28 | 2015-10-21 | 徐国华 | Medicinal preparation for treating eczema |
-
2015
- 2015-09-19 CN CN201510601676.0A patent/CN105079338A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804163A (en) * | 2010-04-21 | 2010-08-18 | 黄泳葛 | Special acne removing medicine and treatment method |
| CN104434743A (en) * | 2013-09-17 | 2015-03-25 | 上海誉盛科贸有限公司 | Pure plant component cosmetic and manufacturing method thereof |
| CN104771744A (en) * | 2015-04-27 | 2015-07-15 | 臧孝国 | Traditional Chinese medicine composition for treating urticaria |
| CN104984160A (en) * | 2015-06-28 | 2015-10-21 | 徐国华 | Medicinal preparation for treating eczema |
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Application publication date: 20151125 |
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