CN105076139A - Bactericidal composition containing fluopyram and fluazinam - Google Patents
Bactericidal composition containing fluopyram and fluazinam Download PDFInfo
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- CN105076139A CN105076139A CN201510560819.8A CN201510560819A CN105076139A CN 105076139 A CN105076139 A CN 105076139A CN 201510560819 A CN201510560819 A CN 201510560819A CN 105076139 A CN105076139 A CN 105076139A
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- fluazinam
- bactericidal composition
- acid amides
- fluorine pyrrole
- pyrrole bacterium
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Abstract
The invention discloses a bactericidal composition containing fluopyram and fluazinam. The bactericidal composition comprises the following active components: fluopyram and fluazinam, wherein the mass ratio of fluopyram to fluazinam is (1: 20)-(20: 1); the mass percent content of the active components in the composition is 5-60%. The bactericidal composition provided by the invention is high in bactericidal activity, delays the occurrence and development of drug resistance of pathogens, decreases the dosage for control in actual production, and is economic, efficient, safe, environment-friendly and particularly remarkable in the control effect on gray mold caused by botrytis cinerea.
Description
Technical field
The present invention relates to disinfectant use in agriculture field, specifically the bactericidal composition of a kind of containing fluopyram and fluazinam.
Background technology
Gray mold is the common and a kind of fungal disease of more difficult control of open country, protecting field crop, and belong to low temperature and high relative humidity type disease, growth of pathogenic bacteria temperature is 20 ~ 30 DEG C, is the disease high-incidence season when temperature 20 ~ 25 DEG C, humidity continue more than 90%.Gray mold, caused by the pathogen of Botrytis cinerea infects, belongs to fungal disease, and flower, really, leaf, stem all can fall ill.The sick seedling look of gray mold is shallow, and the morbidity of blade, petiole is in canescence, and water stain shape, organization softening is to rotting, and during high humidity, there is grey mold on surface.Children's stem is many to come into being irregular water logging spot at petiole base, and very fast deliquescing is rotted, and hang contracting or folding fall, and last sick scutellum rot is withered dies of illness.This disease is a kind of typical aeroborne disease, can propagate with air, current and farming operation.In actual disease control process, be difficult to adopt an effective measure and thoroughly cut off source of infection; When pathogen invades, be also difficult to utterly destroy pathogen, as medicament sprays, be difficult to solve the pathogen in air and dew; And smoke separately canopy, can not solve on the invalid body such as disease leaf, sick fruit or the pathogen of inside by emphasis.
Fluorine pyrrole bacterium acid amides is that an efficient protection preventing and treating Oomycete vegetable disease and result for the treatment of are originated the mixture formula of its uniqueness.This product has excellent system conductive and stronger thin layer penetration power, all has good inhibitory action to each Main Morphology of pathogen, can provide comprehensive for young leaves, stem, stem tuber, young fruit and protect lastingly.Because medicament can absorb fast through blade face, so resistance of rainwater washing against, for vegetables diseases prevention in rainy season provides reliable guarantee.This product is mainly used on all kinds of vegetables and grape crop, control cucumber downy mildew and potato late blight.
The chloro-N-of chemical name: 2,6-bis-[(the chloro-5-trifluoromethyl of 3--2-pyridine radicals) methyl] benzamide
Fluazinam (Dirnethachlon) is new substituted phenyl amines, the spectrum bactericide developed by Japanese Shi Yuan industry companies, has special efficacy to the multiple gray mold that Botrytis cinerea causes.Same benzimidazole, dicarboximide class and in the market existing bactericide without cross resistance.Also good activity is had to germ diseases such as interlink spore genus, Phytophthora, Plasmopara, Sclerotinia and Venturias.This product belongs to 2,6-dinitroanilines, is protective fungicide.The disease caused by grey grape born of the same parents can be prevented and treated with 50 ~ 100g (a.i.)/100L dosage.This product is to interlink spore genus, Botrytis, Phytophthora, Plasmopara, Sclerotinia and black to cultivate Pseudomonas bacterium very effective, also good result is had to the Botrytis cinerea of anti-benzimidazole type and dicarboximide class biocide agent, resistance of rainwater washing against, lasting period is long, have the effect of excellent planting property of control food mite class concurrently, also there is remarkable preventive effect to crucifer club root, also have good preventive effect to by head mold microbial paddy rice damping off.
Chemical name: N-[the chloro-5-of 3-(trifluoromethyl)-2-pyridine radicals] the chloro-4-of-3-(trifluoromethyl)-2,6-dinitroaniline
Structural formula is as follows:
Summary of the invention
The invention provides the bactericidal composition of a kind of containing fluopyram and fluazinam, there is bactericidal activity high, delay pathogen pesticide resistance emergence and development, and dosage total in unit are is declined, economic, efficient, environmental protection, have special efficacy preventing and treating in gray mold.
Two classes are had the bactericide of different mechanism of action by the present invention, i.e. fluorine pyrrole bacterium acid amides and 2, 6-dinitroaniline series bactericidal agent fluazinam is combined, and be processed into the upper easy-to-use preparation of production, be used alone in two kinds of compositions and compare, there is biologically active high, dosage total in unit are declines, greatly reduce dispenser cost, delaying pathogen pesticide resistance emergence and development to a greater extent simultaneously, reduce disease fungus produces resistance risk to single bactericide, extend the service life of each component in bactericidal composition, thus realize economical, efficiently, the goal of the invention of environmental protection.
Technical scheme of the present invention is:
The bactericidal composition of a kind of containing fluopyram and fluazinam, it is characterized in that, the active component of described bactericidal composition is fluorine pyrrole bacterium acid amides and fluazinam, and the mass ratio of fluorine pyrrole bacterium acid amides and fluazinam is 1:20 to 20:1, and in composition, active component mass percentage is 5-60%.
Described containing fluopyram and the bactericidal composition of fluazinam, is characterized in that: described active component fluorine pyrrole bacterium acid amides and the mass ratio of fluazinam are 1:10 to 10:1.
Described containing fluopyram and the bactericidal composition of fluazinam, is characterized in that: described fluorine pyrrole bacterium acid amides and the mass ratio of fluazinam are 1:3-8.
Described containing fluopyram and the bactericidal composition of fluazinam, is characterized in that: described fluorine pyrrole bacterium acid amides and the mass ratio of fluazinam are 1:4-6.
Described containing fluopyram and the bactericidal composition of fluazinam, is characterized in that: the formulation of described bactericidal composition is suspending agent or missible oil.
The bactericidal composition application of described containing fluopyram and fluazinam, is characterized in that: this bactericidal composition is particularly remarkable to gray mold control efficiency.
Remarkable result of the present invention and advantage are:
The present invention has higher control efficiency to grey mold disease, there is notable synergistic effect between two components; Part high price pesticide species can be replaced, and reduce dosage, effectively reduce ecological disruption and environmental pollution, and pomegranate seed output and quality can be improved; In the present invention, fluorine pyrrole bacterium acid amides and fluazinam all belong to the toxicity such as low, and to people and animals, beneficial organism, Environmental security; The pesticide resistance of germ to single medicament can be delayed.
First the EC of fluorine pyrrole bacterium acid amides and fluazinam two single compound (hereinafter referred to as medicament) is measured
50(drug safety index), according to the EC of two single medicaments
50set the portfolio ratio of two medicaments by Wadley method, and according to Wadley coefficient of synergism C value, determine suitable composition ratio, then verified by the abundant method of Sun Yun.
Test objective thing is ash arrhizus bacteria, but does not limit so.Test adopts mycelial growth determination method, makes pastille medium by different disposal, and each process 4 repetitions, connect bacterium after 3 days, investigate the growth inhibitory effect of each process to ash arrhizus bacteria.By the linear regression analysis between the probit value of preventive effect and the logarithm value of serial drug concentration, obtain the EC50 of each medicament, calculate coefficient of synergism (SR) according to Wadley method, and make overall merit accordingly.SR≤0.5 represents to have antagonism, and 0.5 < SR < 1.5 represents to have summation action, and SR >=1.5 are synergistic effect.SR value calculating method is as follows:
EC
50(theoretical value)=(a+b)/(a/EC
50A+ b/EC
50B)
SR=EC
50(theoretical value)/EC
50(real value)
SR≤0.5, then two kinds of medicament mixtures have antagonistic action
SR=0.5 ~ 1.5, then two kinds of medicament mixtures have addition
SR >=1.5, then two kinds of medicament mixtures have synergistic effect
Table 1 fluorine pyrrole bacterium acid amides and fluazinam composition are to the Wadley method measurement result of gray mold
Note: D is fluazinam, and F is fluorine pyrrole bacterium acid amides.
Can analyze from above data, the fluorine pyrrole bacterium acid amides of different proportion and the fungistatic effect of fluazinam composition to ash arrhizus bacteria different, on the whole, its ratio has synergy or addition in the scope of 1:20 to 20:1, and wherein maximum enhancing proportions is the proportioning of fluorine pyrrole bacterium acid amides and fluazinam is 5:1.
Below in conjunction with embodiment, the invention will be further described, but be not limited thereto.
Embodiment
Embodiment 1 (60% fluorine pyrrole bacterium acid amides fluazinam suspending agent)
Composition of raw materials: by mass percentage
Preparation method is as follows:
According to formula, individual component is weighed in proportion, add ball mill ball milling 30 minutes, filter, suction dispersion tank high speed shear was fully ground through sand mill after 3 minutes, controlled solid constituent particle diameter within 2 microns, stir after grinding terminates, obtain suspending agent product.
Embodiment 2 (preparation method of 30% fluorine pyrrole bacterium acid amides fluazinam suspending agent)
Preparation method: identical with embodiment 1.
Embodiment 3 (preparation method of 40% fluorine pyrrole bacterium acid amides fluazinam suspending agent)
Preparation method: identical with embodiment 1.
Embodiment 4 (20% fluorine pyrrole bacterium acid amides fluazinam missible oil)
Preparation method: active component fluorine pyrrole bacterium acid amides is fully dissolved in dimethylbenzene reactor, makes A liquid; Active component fluazinam is fully dissolved in DMF reactor, makes B liquid; Not stopping, under stirring, A liquid is mixed into B liquid, stirring, adding anhydrous calcium salt and NP-10, then adjusting content with solvent xylene.
Embodiment 5 (45% fluorine pyrrole bacterium acid amides fluazinam missible oil)
Composition of raw materials: by mass percentage
Preparation method: with embodiment 4.
Embodiment 6 (preparation method of 48% fluorine pyrrole bacterium acid amides fluazinam missible oil)
Composition of raw materials: by mass percentage
Preparation method: with embodiment 4.
Control efficiency is tested:
The field efficiency test of grape grey mould carries out in peach garden, Wuwei County Portugal, and test area is 0.3hm
2, often process in triplicate, carry out the control of spray medicine at initial bloom stage, carry out preventive effect investigation in dispenser after 20 days, after medication, measure chlorophyll content, before results, investigated the effect of controlling disease, and determine output.Control the results are shown in Table 2.Result shows, bactericidal composition containing fluorine pyrrole bacterium acid amides and fluazinam has good control efficiency to grape grey mould, can reach higher control efficiency under same dose or lower using dosage, and each process preventive effect bacterium of this bactericidal composition is greater than 85%, is significantly higher than contrast medicament.After bactericidal composition (embodiment 1 to the embodiment 6) process of fluorine pyrrole bacterium acid amides and fluazinam, the chlorophyll content in grape leave is also significantly higher than other contrast medicament, and per mu yield also significantly improves (table 2).
The land for growing field crops drug effect * of table 2 fluorine pyrrole bacterium acid amides fluazinam bactericidal composition control grape grey mould
The field efficiency test of Pear black spot carries out in Dangshan County theatre, and at the full-bloom stage of pears to fruit expanding period dispenser 4 times, often process sprays 3 pear trees, repeats 3 times, randomised block design.Carried out preventive effect investigation August 15, and determine output, Simultaneously test chlorophyll content.Result is as shown in table 3, bactericidal composition containing fluorine pyrrole bacterium acid amides and fluazinam has good control efficiency to Pear black spot, can reach higher control efficiency under same dose or lower using dosage, and each process preventive effect bacterium of this bactericidal composition is greater than 85%
Be significantly higher than contrast medicament.After bactericidal composition (embodiment 1 to the embodiment 6) process of fluorine pyrrole bacterium acid amides and fluazinam, the chlorophyll content in Pears is also significantly higher than other contrast medicament, and single fruit weight also significantly improves (table 3).
The land for growing field crops drug effect * of table 3 fluorine pyrrole bacterium acid amides fluazinam bactericidal composition control Pear black spot disease
From the data of table 2 and table 3, the bactericidal composition containing fluorine pyrrole bacterium acid amides and fluazinam has good preventive effect to grape grey mould and Pear black spot, and the preventive effect of different ratio is different.It should be noted that when the proportioning of fluorine pyrrole bacterium acid amides and fluazinam is 5:1, compared with other processes, under lower consumption, but to two kinds of diseases, there is higher preventive effect, show good synergistic function; And indoor biometrics result also shows, when the proportioning of pyraclostrobin and dimethachlon is 5:1, the coefficient of synergism measured is the highest, and the result of the two is consistent.
Finally, it is also to be noted that what enumerate above is only several specific embodiments of the present invention.Obviously, the invention is not restricted to above embodiment, a lot of distortion can also be had.All distortion that those of ordinary skill in the art can directly derive from content disclosed by the invention or associate, all think the scope of protection of the invention.
Claims (6)
1. the bactericidal composition of a containing fluopyram and fluazinam, it is characterized in that, the active component of described bactericidal composition is fluorine pyrrole bacterium acid amides and fluazinam, and the mass ratio of fluorine pyrrole bacterium acid amides and fluazinam is 1:20 to 20:1, and in composition, active component mass percentage is 5-60%.
2. the bactericidal composition of containing fluopyram according to claim 1 and fluazinam, is characterized in that: described active component fluorine pyrrole bacterium acid amides and the mass ratio of fluazinam are 1:10 to 10:1.
3. the bactericidal composition of containing fluopyram according to claim 1 and fluazinam, is characterized in that: described fluorine pyrrole bacterium acid amides and the mass ratio of fluazinam are 1:3-8.
4. the bactericidal composition of containing fluopyram according to claim 1 and fluazinam, is characterized in that: described fluorine pyrrole bacterium acid amides and the mass ratio of fluazinam are 1:4-6.
5. the bactericidal composition of containing fluopyram according to claim 1 and 2 and fluazinam, is characterized in that: the formulation of described bactericidal composition is suspending agent or missible oil.
6. the bactericidal composition application of containing fluopyram according to claim 1 and 2 and fluazinam, is characterized in that: described bactericidal composition has good control efficiency to the various crop disease that Botrytis cinerea causes.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105475313A (en) * | 2015-12-02 | 2016-04-13 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Bactericidal composition containing pyraclostrobin and dimethachlon |
| CN107593710A (en) * | 2016-07-12 | 2018-01-19 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
| CN107683854A (en) * | 2017-10-24 | 2018-02-13 | 天峨县平昌生态农业有限公司 | A kind of nematicide of containing fluopyram and methyl jasmonate |
| CN109105376A (en) * | 2018-09-30 | 2019-01-01 | 浙江海正化工股份有限公司 | Composition pesticide of controlling plant diseases and preparation method thereof |
| CN112616840A (en) * | 2020-12-30 | 2021-04-09 | 天津市汉邦植物保护剂有限责任公司 | Fluopyram and fluazinam compounded granule and preparation process thereof |
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Cited By (5)
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| CN105475313A (en) * | 2015-12-02 | 2016-04-13 | 安徽省农业科学院植物保护与农产品质量安全研究所 | Bactericidal composition containing pyraclostrobin and dimethachlon |
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