CN105055841A - Medicine for treating chronic pharyngitis and preparing method thereof - Google Patents
Medicine for treating chronic pharyngitis and preparing method thereof Download PDFInfo
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- CN105055841A CN105055841A CN201510550086.XA CN201510550086A CN105055841A CN 105055841 A CN105055841 A CN 105055841A CN 201510550086 A CN201510550086 A CN 201510550086A CN 105055841 A CN105055841 A CN 105055841A
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Abstract
The invention provides medicine for treating the chronic pharyngitis, and meanwhile provides a preparing method of the medicine. Pure Chinese herbs including oroxylum indicum, radix ophiopogonis, reddle, salvia miltiorrhiza, fructus trichosanthis, caulis perllae, fructus forsythiae, fructus arctii, dandelions, citrus chachiensis hortorum, semen raphani, folium isatidis, honeysuckles, platycodon grandiflorum, nodus nelumbinis rhizomatis, radix paeoniae alba, terminalia chebula retz, mint and liquorice are carefully selected and scientifically processed to prepare the medicine. The Chinese herbs are simple, compatibility is simple, the Chinese herbs interact, the treatment basis is sufficient, and the effects of clearing away heat and toxic materials, opening the inhibited lung-energy, nourishing yin, relieving the sore throat and diminishing inflammation are achieved; the treatment course is short, cost is low, both symptoms and root causes are treated, maturity is high, side effects and dependency are avoided, and the chronic pharyngitis can be fundamentally cured.
Description
Technical field
The invention provides a kind of medicine for the treatment of chronic pharyngitis, additionally provide its preparation method simultaneously, belong to technical field of traditional Chinese medicine pharmacy.
Background technology
Chronic pharyngitis is under pharyngeal mucosa, mucosa and adenoid chronic inflammatory disease, shows as pharyngeal mucosa chronic congestion, has infiltration of more lymphocytes around its blood vessel, and mucous gland is loose, and secretory function is hyperfunction, and mucilage secretion increases.Its sickness rate of domestic report accounts for the 10%-20% of OtorhinolaryngologicDiseases Diseases, especially comparatively common with cold district.Primary disease is more common in adult, and the course of disease is long, and symptom is obstinate, easily recurs, not easily cures.Most of patients has pharyngeal discomfort, comprises foreign body in pharynx sense, gargalesthesia, burning sensation, dry sensation or excitement and pharyngalgia etc., occurs irritable cough when morning rises.In theory of Chinese medical science, chronic pharyngitis belongs to chronic throat obstruction, chronic pharyngitis, and mainly because lung is insufficiency of the spleen weak, pharyngeal mistake is supported, or evil stagnant in the chronic pharyngopathy being feature with pharyngeal discomfort, pharynx mucosa swelling or atrophy caused by pharynx, controls with nourishing YIN and moistening the lung, removing heat-phlegm, eliminating stagnation sore-throat relieving.
The method of current treatment pharyngitis has: the treatment of operative treatment, local injection, western medicine antibiotics hormone therapy, Chinese patent medicine buccal tablets etc.Operation and local injection treatment make that patient trauma is large, misery is many, and medical expense is high, and general patient is not able to beyond affordability less than ten thousand, and western medicine side effect is large, and cures the symptoms, not the disease and can not effect a radical cure.And treat the Chinese patent medicine of pharyngitis and various decoction, take effect comparatively slow or treat thorough not, being badly in need of the medicine symptomatic treatment chronic pharyngitis providing a kind of curative effect better.
Summary of the invention
The object of the invention is to openly a kind of medicine for the treatment of chronic pharyngitis, evident in efficacy, can Therapeutic Method be simplified, reduce medical expense.
The present invention according to motherland's Chinese medical theory, in conjunction with pathogenesis and the Therapeutic Principle of primary disease, with nourishing YIN and moistening the lung, removing heat-phlegm, eliminating stagnation sore-throat relieving, double sending down the abnormal ascending QI is invigorated blood circulation, and ascending the clear and descending the turbid is method for the treatment of, select pure drug matching, by theory of Chinese medical science prescription, combine in conjunction with modern advanced technologies.
A kind of medicine for the treatment of chronic pharyngitis of the present invention, it is characterized in that being made up by ratio of weight and the number of copies of following medicine:
Semen Oroxyli 5 ~ 10, Radix Ophiopogonis 9 ~ 15, Haematitum 15 ~ 20, Radix Salviae Miltiorrhizae 15 ~ 20, Fructus Trichosanthis 8 ~ 15, Caulis Perillae 8 ~ 15, Fructus Forsythiae 10 ~ 15, Fructus Arctii 10 ~ 15, Herba Taraxaci 10 ~ 15, Pericarpium citri reticuatae chachiensis 6 ~ 10, Semen Raphani 6 ~ 10, Folium Isatidis 8 ~ 15, Flos Lonicerae 15 ~ 20, Radix Platycodonis 6 ~ 10, Nodus Nelumbinis Rhizomatis 5 ~ 10, the Radix Paeoniae Alba 9 ~ 15, Fructus chebulae immaturus 6 ~ 10, Herba Menthae 5 ~ 10, Radix Glycyrrhizae 5 ~ 10.
A kind of manufacture method for the treatment of the medicine of chronic pharyngitis of the present invention:
Take said medicine in proportion, Radix Salviae Miltiorrhizae, Fructus Arctii, Fructus Forsythiae, add 5 ~ 7 times of 60% ~ 80% alcohol heating reflux and extract, reclaim ethanol to thick paste 1.28 ~ 1.30 (80 DEG C); All the other flavour of a drug add 6 ~ 8 times of water gagings, under natural pressure, decoct 2 ~ 3 times, each 1.5 ~ 2 hours, decocting liquid filters, merging filtrate, and being concentrated into relative density is 1.28 ~ 1.30 (80 DEG C) extractum, mix with alcohol extraction cream, drying under reduced pressure, is ground into fine powder, adds the mixing of appropriate maltodextrin, alcohol granulation, makes granule.
The medicine for the treatment of chronic pharyngitis of the present invention can form pharmaceutical preparation with pharmaceutically acceptable carrier or excipient, and described preparation is the peroral dosage forms such as oral liquid, granule, suspension, Emulsion.
[usage and consumption] 3 times on the one.The present invention 7 days is a course for the treatment of, generally takes and takes effect 1-3 the course for the treatment of.
Semen Oroxyli in [side separate] side, property Radix Ophiopogonis are sweet, cool, can nourishing YIN and moistening the lung sore-throat relieving, again can heat clearing away eliminating stagnation; Haematitum sending down the abnormal ascending QI, Radix Salviae Miltiorrhizae nourishing blood and promoting blood circulation, four tastes are monarch drug altogether; Fructus Trichosanthis, Caulis Perillae promoting QI circulation for relieving depression the chest stuffiness relieving; Herba Taraxaci, Fructus Forsythiae, Fructus Arctii are thoroughly loose defends a point pathogenic factor in the exterior, relieving sore-throat by clearing away heat, and Pericarpium citri reticuatae chachiensis, Semen Raphani enter spleen lung, can eliminating stagnation gas, capable stagnant its; Get the property of its heat-clearing and toxic substances removing with Flos Lonicerae, Folium Isatidis, nine tastes are ministerial drug altogether; With Radix Platycodonis, Nodus Nelumbinis Rhizomatis, Herba Menthae, lung qi dispersing, YIN nourishing, sore-throat relieving, cooling blood for hemostasis; Evacuate the wind heat of the part of the body cavity above the diaphragm housing the heart and lungs, add the Radix Paeoniae Alba, the fraud in Fructus chebulae immaturus Tianjin of protecting the moon in case consumption gas burns, the five tastes are adjuvant drug altogether, finally with Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.All medicine synergism QI and blood are taken into account, based on regulating functional activities of qi, by adjustment, recover the normal lifting of mechanism of qi in body, by opening lung qi dispersing gas, fur of removing heat by catharsis, relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, reach heat-clearing and toxic substances removing, removing heat from blood YIN nourishing, sore-throat relieving antiinflammatory, relieving cough and resolving phlegm, protect the merit that lung supports kidney, ailing releasing.Technical solution of the present invention meets the mechanism of tcm treatment according to syndrome differentiation, bases oneself upon the origin of disease, and reasonable recipe science is evident in efficacy, reliable effect, mild in medicine property and, have no side effect.
the curative effect of the present invention being treated to chronic pharyngitis carries out clinical observation:
1,100 routine chronic pharyngitis out-patients are treated: man 70 example, female 30 example;
2, inclusive criteria is diagnosed:
2.1 courses of disease are more than 2 months, and the reasons such as Chang Yin suffers from cold, catch a cold, tired cause exacerbation of symptoms;
2.2 diseases see pharynx foreign body sensation, dry sensation, burning sensation or gargalesthesia, zest dry cough etc.;
2.3 check and see pharyngeal mucous membrane chronic congestion, or thicken, drying, atrophy, thinning, have secretions to adhere to, swallow rear wall lymph
Follicle hypertrophy or lateral pharyngeal band enlargement etc.
3 observation index:
3.1 symptoms: dry pharynx sense, burning sensation, foreign body sensation, itching throat, pharyngalgia, cough etc.
3.2 signs: pharyngeal mucosa hyperemia, retropharyneal folliculosis, lateral pharyngeal band swelling situation etc.
4 medications
Give granule prepared by the present invention, every day 3 times, each 10g, one after each meal.
5 efficacy assessment standards:
Clinical cure: in medication 10 days, cardinal symptom and sign alleviate, in 1 month, clinical symptoms and sign disappear, without recurrence in 2 months.
Effective: medication 2 weeks interior sings and symptomses alleviate, and in 1 month, clinical symptoms and sign disappear, without recurrence in 2 months.
Effective: medication 2 weeks interior sings and symptomses alleviate, and in 1 month, clinical symptoms and part sign disappear.
Invalid: in medication 1 month, symptom has and to alleviate or without alleviating, sign is not improved.
The present invention is through clinical verification, and result is cured: 75 examples; Effective 20 examples, effectively: 4 examples, invalid 1, total effective rate is 99%.
good effect of the present invention is:selected pure herbal prescription, make medicine by science, flavour of a drug are concise, and compatibility is simple, pharmacodynamic interaction, treatment according to fully, has effect of heat-clearing and toxic substances removing, lung qi dispersing YIN nourishing, sore-throat relieving antiinflammatory, short treating period, expense is low, treating both the principal and secondary aspects of a disease, Maturity is higher, and have no side effect, no dependence, fundamentally can cure chronic pharyngitis.
Detailed description of the invention
To be illustrated further description the present invention by following examples, and do not limit the present invention in any way, under the prerequisite not deviating from technical solution of the present invention, any change that those of ordinary skill in the art made for the present invention easily realize or change all will fall within right of the present invention.
embodiment 1
Take Semen Oroxyli 5g, Radix Ophiopogonis 9g, Haematitum 15g, Radix Salviae Miltiorrhizae 15g, Fructus Trichosanthis 8g, Caulis Perillae 8g, Fructus Forsythiae 10g, Fructus Arctii 10g, Herba Taraxaci 10g, Pericarpium citri reticuatae chachiensis 6g, Semen Raphani 6g, Folium Isatidis 8g, Flos Lonicerae 15g, Radix Platycodonis 6g, Nodus Nelumbinis Rhizomatis 5g, Radix Paeoniae Alba 9g, Fructus chebulae immaturus 6g, Herba Menthae 5g, Radix Glycyrrhizae 5g; Radix Salviae Miltiorrhizae, Fructus Arctii, Fructus Forsythiae, add 7 times of 60% ~ 80% alcohol heating reflux and extract, and reclaims ethanol to thick paste 1.28 ~ 1.30 (80 DEG C); All the other flavour of a drug add 8 times of water gagings, under natural pressure, decoct 2 ~ 3 times, each 1.5 ~ 2 hours, decocting liquid filters, merging filtrate, and being concentrated into relative density is 1.28 ~ 1.30 (80 DEG C) extractum, mix with alcohol extraction cream, drying under reduced pressure, is ground into fine powder, adds the mixing of appropriate maltodextrin, alcohol granulation, makes granule.Other option is by under " Pharmacopoeia of People's Republic of China 2010 editions " granule agent item.
embodiment 2
Take Semen Oroxyli 8g, Radix Ophiopogonis 12g, Haematitum 18g, Radix Salviae Miltiorrhizae 18g, Fructus Trichosanthis 12g, Caulis Perillae 12g, Fructus Forsythiae 12g, Fructus Arctii 12g, Herba Taraxaci 12g, Pericarpium citri reticuatae chachiensis 8g, Semen Raphani 8g, Folium Isatidis 12g, Flos Lonicerae 18g, Radix Platycodonis 8g, Nodus Nelumbinis Rhizomatis 8g, Radix Paeoniae Alba 12g, Fructus chebulae immaturus 8g, Herba Menthae 8g, Radix Glycyrrhizae 8g; Radix Salviae Miltiorrhizae, Fructus Arctii, Fructus Forsythiae, add 6 times of 60% ~ 80% alcohol heating reflux and extract, and reclaims ethanol to thick paste 1.28 ~ 1.30 (80 DEG C); All the other flavour of a drug add 7 times of water gagings, under natural pressure, decoct 2 ~ 3 times, each 1.5 ~ 2 hours, decocting liquid filters, merging filtrate, and being concentrated into relative density is 1.28 ~ 1.30 (80 DEG C) extractum, mix with alcohol extraction cream, drying under reduced pressure, is ground into fine powder, adds the mixing of appropriate maltodextrin, alcohol granulation, makes granule.Other option is by under " Pharmacopoeia of People's Republic of China 2010 editions " granule agent item.
embodiment 3
Take Semen Oroxyli 10g, Radix Ophiopogonis 15g, Haematitum 20g, Radix Salviae Miltiorrhizae 20g, Fructus Trichosanthis 15g, Caulis Perillae 15g, Fructus Forsythiae 15g, Fructus Arctii 15g, Herba Taraxaci 15g, Pericarpium citri reticuatae chachiensis 10g, Semen Raphani 10g, Folium Isatidis 15g, Flos Lonicerae 20g, Radix Platycodonis 10g, Nodus Nelumbinis Rhizomatis 10g, Radix Paeoniae Alba 15g, Fructus chebulae immaturus 10g, Herba Menthae 10g, Radix Glycyrrhizae 10g; Radix Salviae Miltiorrhizae, Fructus Arctii, Fructus Forsythiae, add 5 times of 60% ~ 80% alcohol heating reflux and extract, and reclaims ethanol to thick paste 1.28 ~ 1.30 (80 DEG C); All the other flavour of a drug add 6 times of water gagings, under natural pressure, decoct 2 ~ 3 times, each 1.5 ~ 2 hours, decocting liquid filters, merging filtrate, and being concentrated into relative density is 1.28 ~ 1.30 (80 DEG C) extractum, mix with alcohol extraction cream, drying under reduced pressure, is ground into fine powder, adds the mixing of appropriate maltodextrin, alcohol granulation, makes granule.Other option is by under " Pharmacopoeia of People's Republic of China 2010 editions " granule agent item.
the curative effect of medicine of the present invention is proved further by concrete clinical case
case 1
Certain female, 18 years old, the pharyngeal discomfort of persistence, pharyngalgia 3 months, be diagnosed as chronic pharyngitis.Treatment: after taking 1 course for the treatment of of Drug therapy prepared by the embodiment of the present invention 1, pain obviously alleviates.Take medicine 3 courses for the treatment of, situation of having sore throat disappears.
case 2
Certain man, 32 years old, foreign body in pharynx sense, irritant cough, increased the weight of 5 months when swallowing.Treatment: take Drug therapy prepared by the embodiment of the present invention 2, take medicine after 1 course for the treatment of, irritable cough alleviates before comparatively taking medicine, and after 3 courses for the treatment of of taking medicine continuously, pharyngeal foreign body sensation and irritable cough symptom disappear substantially.
case 3
Certain man, 55 years old, readme started cough after catching a cold before 2 months, pharyngalgia.After diagnosing, pharyngeal mucous membrane chronic congestion, retropharyneal folliculosis, belongs to after diseases caused by exogenous pathogenic factor cause acute pharyngitis and transfers chronic pharyngitis to.Treatment: give the present embodiment 3 granule, after 3 days, pharyngalgia, cough symptom take a turn for the better, and after 3 courses for the treatment of of taking medicine continuously, clinical symptoms disappears substantially.
case 4
Certain man, 55 years old, the pharyngitis that long-term smoking causes, irritable cough, dry pharynx.Treatment: with the embodiment of the present invention 2 medicine, 3 times/day, treat after one month gradually light, patient feels: throat is comfortable, and cough disappears, and visits without recurrence after 2 months.
case 5
Zhang, man, 51 years old, 30 years lengths of smoking, clinical symptoms: pharyngeal burning sensation, itching throat, cough.Treatment: with the embodiment of the present invention 3 medicine, 3 times/day, treat after one month gradually light, patient feels: above-mentioned clinical symptom disappearance, visits without recurrence after 2 months.
Claims (3)
1. treat a medicine for chronic pharyngitis, it is characterized in that being made up by ratio of weight and the number of copies of following medicine:
Semen Oroxyli 5 ~ 10, Radix Ophiopogonis 9 ~ 15, Haematitum 15 ~ 20, Radix Salviae Miltiorrhizae 15 ~ 20, Fructus Trichosanthis 8 ~ 15, Caulis Perillae 8 ~ 15, Fructus Forsythiae 10 ~ 15, Fructus Arctii 10 ~ 15, Herba Taraxaci 10 ~ 15, Pericarpium citri reticuatae chachiensis 6 ~ 10, Semen Raphani 6 ~ 10, Folium Isatidis 8 ~ 15, Flos Lonicerae 15 ~ 20, Radix Platycodonis 6 ~ 10, Nodus Nelumbinis Rhizomatis 5 ~ 10, the Radix Paeoniae Alba 9 ~ 15, Fructus chebulae immaturus 6 ~ 10, Herba Menthae 5 ~ 10, Radix Glycyrrhizae 5 ~ 10.
2. a kind of manufacture method for the treatment of the medicine of chronic pharyngitis according to claim 1, comprises the following steps:
Take said medicine in proportion, Radix Salviae Miltiorrhizae, Fructus Arctii, Fructus Forsythiae, add 5 ~ 7 times of 60% ~ 80% alcohol heating reflux and extract, reclaim ethanol to thick paste 1.28 ~ 1.30 (80 DEG C); All the other flavour of a drug add 6 ~ 8 times of water gagings, under natural pressure, decoct 2 ~ 3 times, each 1.5 ~ 2 hours, decocting liquid filters, merging filtrate, and being concentrated into relative density is 1.28 ~ 1.30 (80 DEG C) extractum, mix with alcohol extraction cream, drying under reduced pressure, is ground into fine powder, adds the mixing of appropriate maltodextrin, alcohol granulation, makes granule.
3. the medicine for the treatment of chronic pharyngitis according to claim 1 can form pharmaceutical preparation with pharmaceutically acceptable carrier or excipient, and described preparation is the peroral dosage forms such as oral liquid, granule, suspension, Emulsion.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106615531A (en) * | 2016-09-27 | 2017-05-10 | 合肥智博生物科技有限公司 | Throat-clearing and sore-throat-relieving candies and preparation method thereof |
| CN112755120A (en) * | 2021-03-10 | 2021-05-07 | 菏泽市产业技术研究院 | Traditional Chinese medicine preparation for treating chronic pharyngitis and preparation method thereof |
| CN115252724A (en) * | 2022-07-27 | 2022-11-01 | 佛山市高明区人民医院 | Traditional Chinese medicine composition for treating pharyngitis, product and preparation method |
| CN118477149A (en) * | 2024-07-16 | 2024-08-13 | 江西汉和生物科技有限公司 | Traditional Chinese medicine composition for treating pharyngitis |
Citations (1)
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| CN101816757A (en) * | 2010-06-02 | 2010-09-01 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating antiaditis and preparation method thereof |
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2015
- 2015-09-01 CN CN201510550086.XA patent/CN105055841A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101816757A (en) * | 2010-06-02 | 2010-09-01 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating antiaditis and preparation method thereof |
Non-Patent Citations (2)
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| 宣伟军: "中医药治疗慢性咽炎近况", 《广西中医药》 * |
| 符信高等: "利咽饮治疗慢性咽炎61例", 《江西中医药》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106615531A (en) * | 2016-09-27 | 2017-05-10 | 合肥智博生物科技有限公司 | Throat-clearing and sore-throat-relieving candies and preparation method thereof |
| CN112755120A (en) * | 2021-03-10 | 2021-05-07 | 菏泽市产业技术研究院 | Traditional Chinese medicine preparation for treating chronic pharyngitis and preparation method thereof |
| CN115252724A (en) * | 2022-07-27 | 2022-11-01 | 佛山市高明区人民医院 | Traditional Chinese medicine composition for treating pharyngitis, product and preparation method |
| CN115252724B (en) * | 2022-07-27 | 2023-07-11 | 佛山市高明区人民医院 | Traditional Chinese medicine composition for treating pharyngitis, product and preparation method |
| CN118477149A (en) * | 2024-07-16 | 2024-08-13 | 江西汉和生物科技有限公司 | Traditional Chinese medicine composition for treating pharyngitis |
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Application publication date: 20151118 |