CN101129636A - Medicine for treating nasal inflammation - Google Patents
Medicine for treating nasal inflammation Download PDFInfo
- Publication number
- CN101129636A CN101129636A CNA2007101311544A CN200710131154A CN101129636A CN 101129636 A CN101129636 A CN 101129636A CN A2007101311544 A CNA2007101311544 A CN A2007101311544A CN 200710131154 A CN200710131154 A CN 200710131154A CN 101129636 A CN101129636 A CN 101129636A
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- CN
- China
- Prior art keywords
- radix
- herba
- medicine
- grams
- chlorphenamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000003814 drug Substances 0.000 title claims abstract description 39
- 229940079593 drug Drugs 0.000 title claims description 14
- 206010028741 Nasal inflammation Diseases 0.000 title abstract 2
- DBAKFASWICGISY-BTJKTKAUSA-N Chlorpheniramine maleate Chemical compound OC(=O)\C=C/C(O)=O.C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 DBAKFASWICGISY-BTJKTKAUSA-N 0.000 claims abstract description 16
- 241000628997 Flos Species 0.000 claims abstract description 16
- 239000009670 cang er zi wan Substances 0.000 claims abstract description 11
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims abstract description 8
- 239000002552 dosage form Substances 0.000 claims abstract description 5
- 239000007788 liquid Substances 0.000 claims abstract description 5
- 239000002775 capsule Substances 0.000 claims abstract description 4
- 229960003291 chlorphenamine Drugs 0.000 claims description 15
- 206010061218 Inflammation Diseases 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 230000004054 inflammatory process Effects 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims description 2
- 201000010099 disease Diseases 0.000 abstract description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 8
- 241001529821 Agastache Species 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 206010039083 rhinitis Diseases 0.000 description 11
- 238000009835 boiling Methods 0.000 description 8
- 238000002386 leaching Methods 0.000 description 8
- 201000009890 sinusitis Diseases 0.000 description 7
- 230000001154 acute effect Effects 0.000 description 4
- 201000009151 chronic rhinitis Diseases 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 201000009240 nasopharyngitis Diseases 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 230000002421 anti-septic effect Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 210000001331 nose Anatomy 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 210000003695 paranasal sinus Anatomy 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicine for treating nasal inflammation, which is prepared from fifteen traditional Chinese medicines of flos Magnoliae, fructus Xanthii, flos Lonicerae, herba Centipedae, rhizoma Acori Calami, herba Agastaches, folium Perillae, herba Menthae, radix Gentianae, radix bupleuri, rhizoma Chuanxiong, radix Angelicae Dahuricae, radix Platycodi, herba Houttuyniae and radix Scutellariae, and a small amount of western medicine chlorphenamine maleate. Mixing with pharmaceutically acceptable carrier, and making into capsule, oral liquid or other suitable dosage forms by conventional method. The aims of treating both principal and secondary aspect of disease and curing diseases after taking the medicine are achieved.
Description
Technical field
The present invention relates to be used for the treatment of the medicine of acute and chronic rhinitis, sinusitis.
Background technology
Rhinitis, sinusitis are frequently-occurring disease, the commonly encountered diseases among the crowd.To show as the course of disease long more, and easily recurrence brings a lot of inconvenience for patient's living and studying.At present the treatment of rhinitis, sinusitis is not still had special-purpose specific medicament, use general anti-inflammation drugs and symptomatic treatment more.The treatment acute and chronic rhinitis of selling on the market, the medicine of sinusitis can't be satisfactory at aspects such as effective percentage, persistency, relapse rates.Its deficiency is, or can not be effective to everyone, or relapse rate is higher after stopping using medicine.Therefore be necessary to excavate more effective, easy to use, cheap treatment acute and chronic rhinitis, the medicine of sinusitis.And its unique advantage and value is arranged according to the medicine of the theoretical development of Chinese medicine and pharmacy.
Summary of the invention
The object of the present invention is to provide a kind of medicine for the treatment of nosal inflammation, it is to serve as the pharmaceutical preparation of main preparation with the Chinese medicine natural drug, and it can reach treating both the principal and secondary aspects of a disease aspect treatment acute and chronic rhinitis, sinusitis, better curative effect is arranged.
The present invention seeks to realize by the following method: crude drug of the present invention is equipped with a small amount of Western medicine chlorphenamine based on Flos Magnoliae flower, Fructus Xanthii, Flos Lonicerae, Herba Centipedae, Rhizoma Acori Graminei, Herba Pogostemonis, Folium Perillae, Herba Menthae, Radix Gentianae, Radix Bupleuri, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Radix Platycodonis, Herba Houttuyniae, 15 kinds of Chinese medicine natural drugs of Radix Scutellariae.They are equipped with the pharmacy acceptable carrier, adopt common process, manufacture capsule, oral liquid or other dosage forms that is suitable for.
Pharmaceutical compositions consumption proportion scope of the present invention is:
Flos Magnoliae flower 10-14% Fructus Xanthii 8-12% Flos Lonicerae 6-11%
Herba Centipedae 6-11% Rhizoma Acori Graminei 3-7% Herba Pogostemonis 4-9%
Folium Perillae 3-8% Herba Menthae 3-7% Radix Gentianae 4-9%
Radix Bupleuri 4-9% Rhizoma Chuanxiong 4-9% Radix Angelicae Dahuricae 3-7%
Radix Platycodonis 3-7% Herba Houttuyniae 6-11% Radix Scutellariae 3-7%
Chlorphenamine 0.1-0.4%
Its formulation method:
The Chinese medicine preprocessing need only be pulverized Fructus Xanthii.
1. glue wafer.Except that chlorphenamine and Herba Menthae, with all the other 14 kinds of Chinese medicine mixing watered boilings 3 times, decocted 1-3 hour at every turn, cross the leaching decoction liquor; The leaching decoction liquor was crossed in the Herba Menthae watered boiling in 20-40 minute; Merge each time decoction liquor, reheat is condensed into paste, dries then or dries, and row is pulverized again, drops into chlorphenamine, and mix homogeneously incapsulates, and is finished product.
2. system oral liquid.Except that chlorphenamine and Herba Menthae, with all the other 14 kinds of Chinese medicine mixing watered boilings 3 times, decocted 1-3 hour at every turn, cross the leaching decoction liquor; The leaching decoction liquor was crossed in the Herba Menthae watered boiling in 20-40 minute; Merge each time decoction liquor, add chlorphenamine and antiseptic, packing is standby.
3. also can make dosage forms such as tablet, honeyed pill, the watered pill, granular pattern electuary by usual way.More than various dosage forms adult consumptions every day be equivalent to crude drug 120-160 gram, divide and take for 2-3 time.
Motherland's medical science thinks, rhinitis, sinusitis are many because of the evil poison of diseases caused by exogenous pathogenic factor, wind and heat in the lung meridian, and the gallbladder internal organs is hot and suffocating, the damp-heat in the spleen and stomach circulation criminal's of going up intrusion nasal sinuses and sending out.Clinical manifestation is nasal obstruction, the nasal mucus of suppurating, headache and general malaise.In the prescription of the present invention Flos Magnoliae, Fructus Xanthii, Herba Centipedae dispel the wind, the sharp key of pain relieving, stuffy nose relieving; Flos Lonicerae, Herba Houttuyniae, flower bud perfume (or spice), the bath of Radix Angelicae Dahuricae dispelling wind are wet, heat-clearing and toxic substances removing, detumescence and apocenosis: river live in degradation blood circulation of qi promoting, wind-expelling pain-stopping; Radix Platycodonis ascending lung qi, priming are up.All medicines share, and play altogether that the bath of dispeling the wind is wet, the effect of heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the sharp key of stuffy nose relieving.Add an amount of chlorphenamine again,, reach treating both the principal and secondary aspects of a disease, the purpose that As the medicine took effect, the symptoms lessened with the effect of the antiallergic action of strengthening pure Chinese medicine.
The specific embodiment
Below in conjunction with embodiment invention is described further;
Embodiment 1 produces capsule
Flos Magnoliae is spent 240 grams, Fructus Xanthii 200 grams, Flos Lonicerae 160 grams, Herba Centipedae 160 grams, Rhizoma Acori Graminei 100 grams, Herba Pogostemonis 120 grams, Folium Perillae 100 grams, Herba Menthae 100 grams, Radix Gentianae 120 grams, Radix Bupleuri 120 grams, Rhizoma Chuanxiong 120 grams, the Radix Angelicae Dahuricae 100 grams, Radix Platycodonis 100 grams, Herba Houttuyniae 160 grams, Radix Scutellariae 100 grams, chlorphenamine 4 grams.
Above crude drug is pulverized Fructus Xanthii except that chlorphenamine and Herba Menthae in advance, with all the other 13 kinds of Chinese medicine mixing watered boilings 3 times, decocts 1-3 hour at every turn, crosses the leaching decoction liquor; The leaching decoction liquor was crossed in the Herba Menthae watered boiling in 30 minutes; Merge each time decoction liquor, reheat is condensed into paste, oven dry then, and row is pulverized again, drops into chlorphenamine, and mix homogeneously incapsulates, and is finished product.
The total consumption of present embodiment crude drug is 2004 grams, is equivalent to crude drug 120-160 gram by adult's consumption every day and calculates, and is equivalent to the consumption in 2 weeks of adult patient (14 days) approximately.
Embodiment 2 produces oral liquid
Flos Magnoliae is spent 220 grams, Fructus Xanthii 220 grams, Flos Lonicerae 140 grams, Herba Centipedae 180 grams, Rhizoma Acori Graminei 80 grams, Herba Pogostemonis 140 grams, Folium Perillae 90 grams, Herba Menthae 120 grams, Radix Gentianae 100 grams, Radix Bupleuri 140 grams, Rhizoma Chuanxiong 100 grams, the Radix Angelicae Dahuricae 120 grams, Radix Platycodonis 80 grams, Herba Houttuyniae 180 grams, Radix Scutellariae 100 grams, chlorphenamine 3 grams.
Above crude drug is pulverized Fructus Xanthii except that chlorphenamine and Herba Menthae in advance, and with all the other 13 kinds of Chinese medicine mixing watered boilings 3 times, each time decocting time was respectively 3 hours, 2 hours, 1 hour.Cross the leaching decoction liquor; The leaching decoction liquor was crossed in the Herba Menthae watered boiling in 30 minutes; Merge each time decoction liquor, add chlorphenamine and antiseptic, mix homogeneously, packing is finished product.
The total consumption of present embodiment crude drug is 2013 grams, is equivalent to crude drug 120-160 gram by adult's consumption every day and calculates, and is equivalent to the consumption in 2 weeks of adult patient (14 days) approximately.
Claims (1)
1. medicine for the treatment of nosal inflammation, based on Flos Magnoliae flower, Fructus Xanthii, Flos Lonicerae, Herba Centipedae, Rhizoma Acori Graminei, Herba Pogostemonis, Folium Perillae, Herba Menthae, Radix Gentianae, Radix Bupleuri, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Radix Platycodonis, Herba Houttuyniae, 15 kinds of Chinese medicine natural drugs of Radix Scutellariae, be equipped with a small amount of Western medicine chlorphenamine; They are equipped with the pharmacy acceptable carrier, adopt common process, manufacture capsule, oral liquid or other dosage forms that is suitable for, it is characterized in that: this pharmaceutical compositions consumption proportion scope is:
Flos Magnoliae flower 10-14% Fructus Xanthii 8-12% Flos Lonicerae 6-11%
Herba Centipedae 6-11% Rhizoma Acori Graminei 3-7% Herba Pogostemonis 4-9%
Folium Perillae 3-8% Herba Menthae 3-7% Radix Gentianae 4-9%
Radix Bupleuri 4-9% Rhizoma Chuanxiong 4-9% Radix Angelicae Dahuricae 3-7%
Radix Platycodonis 3-7% Herba Houttuyniae 6-11% Radix Scutellariae 3-7%
Chlorphenamine 0.1-0.4%
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101311544A CN101129636A (en) | 2007-08-22 | 2007-08-22 | Medicine for treating nasal inflammation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101311544A CN101129636A (en) | 2007-08-22 | 2007-08-22 | Medicine for treating nasal inflammation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101129636A true CN101129636A (en) | 2008-02-27 |
Family
ID=39127148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101311544A Withdrawn CN101129636A (en) | 2007-08-22 | 2007-08-22 | Medicine for treating nasal inflammation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101129636A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102805805A (en) * | 2012-08-25 | 2012-12-05 | 兰恒志 | Medicament for treating rhinitis and preparation method thereof |
| CN103536721A (en) * | 2013-10-21 | 2014-01-29 | 张春宏 | Traditional Chinese medicine for treating chronic nasosinusitis |
| CN103720875A (en) * | 2014-01-09 | 2014-04-16 | 陈立娥 | Traditional Chinese medicine ointment patch for treating chronic rhinitis and preparation method thereof |
| CN103768364A (en) * | 2013-12-20 | 2014-05-07 | 霍山县中医院 | Traditional Chinese medicinal composition for treating chronic rhinitis |
| CN104258194A (en) * | 2014-10-10 | 2015-01-07 | 王全红 | Traditional Chinese medicine combination for curing rhinitis and preparation method thereof |
| CN107242930A (en) * | 2017-06-06 | 2017-10-13 | 沈非儿 | Warm nose patch and its moulding process |
| CN108403863A (en) * | 2018-05-04 | 2018-08-17 | 杨伟东 | A kind of nose speed health preparation for treating rhinitis |
-
2007
- 2007-08-22 CN CNA2007101311544A patent/CN101129636A/en not_active Withdrawn
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102805805A (en) * | 2012-08-25 | 2012-12-05 | 兰恒志 | Medicament for treating rhinitis and preparation method thereof |
| CN103536721A (en) * | 2013-10-21 | 2014-01-29 | 张春宏 | Traditional Chinese medicine for treating chronic nasosinusitis |
| CN103536721B (en) * | 2013-10-21 | 2016-04-13 | 蔡秀菊 | The Chinese medicine for the treatment of chronic sinusitis |
| CN103768364A (en) * | 2013-12-20 | 2014-05-07 | 霍山县中医院 | Traditional Chinese medicinal composition for treating chronic rhinitis |
| CN103768364B (en) * | 2013-12-20 | 2016-05-04 | 霍山县中医院 | A kind of Chinese medicine composition for the treatment of rhinitis chronic |
| CN103720875A (en) * | 2014-01-09 | 2014-04-16 | 陈立娥 | Traditional Chinese medicine ointment patch for treating chronic rhinitis and preparation method thereof |
| CN104258194A (en) * | 2014-10-10 | 2015-01-07 | 王全红 | Traditional Chinese medicine combination for curing rhinitis and preparation method thereof |
| CN107242930A (en) * | 2017-06-06 | 2017-10-13 | 沈非儿 | Warm nose patch and its moulding process |
| CN108403863A (en) * | 2018-05-04 | 2018-08-17 | 杨伟东 | A kind of nose speed health preparation for treating rhinitis |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C04 | Withdrawal of patent application after publication (patent law 2001) | ||
| WW01 | Invention patent application withdrawn after publication |