CN101194940A - Anti-inflammation medicament for treating toothache and preparation method thereof - Google Patents
Anti-inflammation medicament for treating toothache and preparation method thereof Download PDFInfo
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- CN101194940A CN101194940A CNA2008100638089A CN200810063808A CN101194940A CN 101194940 A CN101194940 A CN 101194940A CN A2008100638089 A CNA2008100638089 A CN A2008100638089A CN 200810063808 A CN200810063808 A CN 200810063808A CN 101194940 A CN101194940 A CN 101194940A
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Abstract
The invention provides an inflammatory medicament for curing toothache and a process for preparation, raw material is prepared according to a weight ratio that asarum 1-2 parts, pollen 10-15 parts, bile grass 10-15, glycyrrhiza 2-5 parts, gypsum 25-30 parts, rhubarb 7-8 parts, white peony root 10-15 parts and ginseng 10-15 parts. The process comprises disintegrating ginseng to pass100 mesh sieve after being dried in 60 DEG C, breaking up the other drugs, decocting 3 times after water is added to immerse for 3 hours, and decocting time of the three times are respectively 2 hours, 1 hour, and 1 hour, combining decocted fluid and the fluid is concentrated to condensed plaster whose weight ratio is 1.21 to 1.25 after the decocted fluid of the three times are respectively filtered, adding alcohol after being cooled till the content of weight ratio of the alcohol reaches 60%, stewing 24 hours, filtering, concentrating to condensed plaster shape after alcohol is recovered from filter liquor, reducing pressure to dry, disintegrating, passing through 80 mesh sieve, and then evenly mixing with the ginseng to prepare water-paste pills. Products which are prepared by the process of the invention are used for curing toothache diseases, such as toothache due to pathogenic wind-fire, toothache due to excessive stomach-heat, toothache due to liver fire, toothache due to deficiency of the kidney, and alveolar abscess and the like. The invention has obvious curative effect.
Description
(1) technical field
The present invention relates to be a kind of be the pharmaceutical product of primary raw material with the plant, specifically a kind ofly treat one of toothache and want preparation.The invention still further relates to the manufacture method of this medicinal preparation.
(2) background technology
The technical method of dental treatment toothache of generally adopting and abscess etc. easily produces the disadvantage that take stopgap measures now.Generally be interim alleviating pain, not only curative effect is relatively poor, and cures often recurrence of back.Because existing medicine and method are poor to the therapeutic effect of oral diseases such as toothache, make a lot of patients' the illness of having a toothache be difficult to remove, brought great misery to the patient.
(3) summary of the invention
The object of the present invention is to provide the anti-inflammation drugs that is difficult for the treatment toothache of recurrence after a kind of instant effect, effective, short treating period, the healing.Purpose Rhopilema esculenta of the present invention with a kind of manufacture method for the treatment of the anti-inflammation drugs of toothache is provided.
The object of the present invention is achieved like this: product of the present invention is that Herba Asari 1-2 part, pollen 10-15 part, Radix Gentianae 10-15 part, Radix Glycyrrhizae 2-5 part, Gypsum Fibrosum 25-30 part, Radix Et Rhizoma Rhei 7-8 part, Radix Paeoniae Alba 10-15 part and Radix Ginseng 10-15 part are made by weight ratio.
The manufacture method of product of the present invention is:
According to weight ratio is that the ratio of Herba Asari 1-2 part, pollen 10-15 part, Radix Gentianae 10-15 part, Radix Glycyrrhizae 2-5 part, Gypsum Fibrosum 25-30 part, Radix Et Rhizoma Rhei 7-8 part, Radix Paeoniae Alba 10-15 part and Radix Ginseng 10-15 part is got raw material ready; Radix Ginseng had been crushed to 100 mesh sieves with it after the drying under 60 ℃ of temperature; In addition all medicines of remainder are carried out cataclasm, soak 3 hours after, decoct 3 times, 3 times decocting time was respectively 2 hours, 1 hour, 1 hour; After 3 times decoction liquor is filtered respectively, merge decoction liquor and be concentrated into the thick paste that proportion is 1.21-1.25, the cooling back adds ethanol, after extremely alcoholic acid weight ratio content reaches 60%, left standstill 24 hours, and filtered, be concentrated into the thick paste shape behind the filtrate recycling ethanol, drying under reduced pressure is pulverized, and crosses 80 mesh sieves; With Radix Ginseng powder's mixing, make the watered pill then.
Gypsum Fibrosum among the present invention: Gan Xin, Great Cold.Attach to the lung and stomach meridians, give birth to and use clearing away heat-fire, relieving restlessness is quenched the thirst.Be used for the high Sheng of stomach-fire, headache, toothache; Radix Gentianae: bitter cold, return liver, gallbladder meridian, heat clearing and damp drying, eliminating pathogen in the liver, gallbladder fire.But more than two medicines share lung heat clearing, the fire of stomach, liver, gallbladder is principal agent altogether.Pollen: sweet, little hardship, be slightly cold, attach to the lung and stomach meridians.Cure mainly clearing away heat and promoting production of body fluid, detumescence and apocenosis.Herba Asari: Xin Wen, return lung, heart kidney thin, expelling wind and cold, understand things pain-stopping promptly helps the Gypsum Fibrosum pain relieving, and it is cold excessively to help Gypsum Fibrosum again, and two medicines share and complement each other.The Radix Paeoniae Alba: bitter, acid, be slightly cold, return Liver Channel, cure mainly the suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation.The Herba Asari antalgic; The Gypsum Fibrosum clearing away heat to alleviate pain; Radix Paeoniae Alba relieving spasm to stop pain, three medicines share, and pain relieving is imitated as the small wooden raft drum.Radix Et Rhizoma Rhei: bitter cold, return spleen, stomach, large intestine, liver, pericardium channel.The function purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation, Radix Et Rhizoma Rhei can help Gypsum Fibrosum to rush down gastric heat, not only can lung heat clearing inflammation (the lung and the large intestine being interior-exteriorly related) but also can removing pathogenic heat from blood and toxic substance from the body, so pry-is clear, bitterly, swollen disappearing, then pain is ended.Radix Glycyrrhizae: sweet flat, GUIXIN, lung, spleen, stomach warp, function invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.So but all medicines are pieced together tonifying five ZANG-organs.Radix Ginseng: strongly invigorating primordial QI, invigorating the spleen to benefit the lung, promoting the production of body fluid and inducing sedation of the mind, insufficiency of the spleen lack of appetite, thirsty empty win for a long time, palpitation with fear, insomnia etc.So this medicine not only ends toothache, the physical weakness due to can strongly having a toothache admittedly again.
Prescription of the present invention is based on Compendium of Material Medica, is purpose to effect a permanent cure, and in medical practice for many years, constantly sums up and develops.Product through method preparation of the present invention makes the patient fundamentally cure odontopathy, and through for many years clinical practice and checking, this prescription can be treated multiple toothache and inflammation.Prescription of the present invention has overcome the deficiency that existing medicine easily produces the disadvantage that take stopgap measures, if return characteristics through, collateral dredging in conjunction with Chinese medicine, fundamentally treats various toothache, receives that the patient suffering is little, and treatment time is short, the special effect of disease cure rate height.
The product that adopts method of the present invention to make is applicable to acute toothache, gastric heat toothache, liver-fire toothache, toothache class diseases such as suffer from a deficiency of the kidney toothache, alveolar abscess, and is evident in efficacy.In order to verify effect of the present invention, the product that adopts method of the present invention to obtain has been carried out the clinical observation checking, visual report is as follows:
One, clinical data:
Select outpatient's 247 examples, wherein male 141 examples, women 106 examples, maximum 59 years old age, minimal ages 9 years old.
1, treatment group: use the prescription of the anti-inflammation drugs of having a toothache and all kinds of toothache patient 178 examples of analgesic antiphlogistic pill for curing that manufacture method makes by treatment of the present invention, wherein male 96 examples, women 82 examples, the oldest is 58 years old, minimum 9 years old, the course of disease did not wait in one day extremely all around.
2, matched group: use all kinds of toothache patient 69 examples of toothache peace treatment, male 45 examples, women 24 examples, the course of disease one day to around, age 18-59 year.
Two, Therapeutic Method:
1, treatment group: to acute toothache, gastric heat toothache, liver-fire toothache, the odontopathy such as toothache, alveolar abscess of suffering from a deficiency of the kidney, it is oral that the patient gives the analgesic antiphlogistic ball, each 2 balls of being grown up, every day three times, each 1 ball of child, every day three times, pain relieving after 1-2 days.
2, matched group: be used for the similar patient of toothache peace treatment, each 2 of clothes toothache every day peace 3 times, all pain relievings.
Three, therapeutic effect (seeing the following form)
Two groups of Comparison of therapeutic before and after the medication
| Disease | Matched group | The treatment group | ||||
| Number before the medication | Treatment number after the medication | Cure rate (%) | Number before the medication | Treatment number after the medication | Cure rate (%) | |
| Acute toothache | 20 | 12 | 60 | 55 | 52 | 94.5 |
| The gastric heat toothache | 14 | 6 | 42.9 | 30 | 27 | 90 |
| The liver-fire toothache | 12 | 8 | 66.7 | 40 | 36 | 90 |
| The toothache of suffering from a deficiency of the kidney | 10 | 4 | 40 | 25 | 23 | 92 |
| Alveolar abscess | 13 | 6 | 46.2 | 28 | 26 | 92.9 |
Treatment group and matched group there were significant differences P＞0.05, thus visible analgesic antiphlogistic ball has significant clinical efficacy to treating various toothache.
(4) specific embodiment
For example the present invention is done in more detail below and describes:
According to weight ratio is that the ratio of 12 parts of 2 parts of Herba Asaris, 12 parts of pollen, 12 parts of Radix Gentianae, 3 parts in Radix Glycyrrhizae, 30 parts in Gypsum Fibrosum, 7.5 parts of Radix Et Rhizoma Rhei, 12 parts of the Radix Paeoniae Albas and Radix Ginsengs is got raw material ready; Radix Ginseng had been crushed to 100 mesh sieves with it after the drying under 60 ℃ of temperature; In addition all medicines of remainder are carried out cataclasm, soak 3 hours after, decoct 3 times, 3 times decocting time was respectively 2 hours, 1 hour, 1 hour; After 3 times decoction liquor is filtered respectively, merge decoction liquor and be concentrated into the thick paste that proportion is 1.21-1.25 (80 ℃ of surveys), the cooling back adds ethanol, after extremely alcoholic acid weight ratio content reaches 60%, left standstill 24 hours, filter, be concentrated into the thick paste shape behind the filtrate recycling ethanol, drying under reduced pressure is pulverized, and crosses 80 mesh sieves; With Radix Ginseng powder's mixing, make the watered pill (per 40 pastille 5.5g) then.
Claims (3)
1. anti-inflammation drugs for the treatment of toothache, it is characterized in that: it is that Herba Asari 1-2 part, pollen 10-15 part, Radix Gentianae 10-15 part, Radix Glycyrrhizae 2-5 part, Gypsum Fibrosum 25-30 part, Radix Et Rhizoma Rhei 7-8 part, Radix Paeoniae Alba 10-15 part and Radix Ginseng 10-15 part are made by weight ratio.
2. the anti-inflammation drugs of treatment toothache according to claim 1, it is characterized in that: it is made for 12 parts by 2 parts of Herba Asaris, 12 parts of pollen, 12 parts of Radix Gentianae, 3 parts in Radix Glycyrrhizae, 30 parts in Gypsum Fibrosum, 7.5 parts of Radix Et Rhizoma Rhei, 12 parts of the Radix Paeoniae Albas and Radix Ginseng.
3. manufacture method for the treatment of the anti-inflammation drugs of toothache is characterized in that: according to weight ratio is that the ratio of Herba Asari 1-2 part, pollen 10-15 part, Radix Gentianae 10-15 part, Radix Glycyrrhizae 2-5 part, Gypsum Fibrosum 25-30 part, Radix Et Rhizoma Rhei 7-8 part, Radix Paeoniae Alba 10-15 part and Radix Ginseng 10-15 part is got raw material ready; Radix Ginseng had been crushed to 100 mesh sieves with it after the drying under 60 ℃ of temperature; In addition all medicines of remainder are carried out cataclasm, soak 3 hours after, decoct 3 times, 3 times decocting time was respectively 2 hours, 1 hour, 1 hour; After 3 times decoction liquor is filtered respectively, merge decoction liquor and be concentrated into the thick paste that proportion is 1.21-1.25, the cooling back adds ethanol, after extremely alcoholic acid weight ratio content reaches 60%, left standstill 24 hours, and filtered, be concentrated into the thick paste shape behind the filtrate recycling ethanol, drying under reduced pressure is pulverized, and crosses 80 mesh sieves; With Radix Ginseng powder's mixing, make the watered pill then.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100638089A CN101194940A (en) | 2008-01-04 | 2008-01-04 | Anti-inflammation medicament for treating toothache and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2008100638089A CN101194940A (en) | 2008-01-04 | 2008-01-04 | Anti-inflammation medicament for treating toothache and preparation method thereof |
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| CN101194940A true CN101194940A (en) | 2008-06-11 |
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| CNA2008100638089A Pending CN101194940A (en) | 2008-01-04 | 2008-01-04 | Anti-inflammation medicament for treating toothache and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106333989A (en) * | 2016-11-19 | 2017-01-18 | 张忠远 | Pharmaceutical composition for treating wind-heat toothache |
| FR3078886A1 (en) * | 2018-03-15 | 2019-09-20 | Liu Zhengyu | MEDICAMENT FOR TREATING TOOTHBORNE AND METHOD FOR PREPARING THE SAME |
-
2008
- 2008-01-04 CN CNA2008100638089A patent/CN101194940A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106333989A (en) * | 2016-11-19 | 2017-01-18 | 张忠远 | Pharmaceutical composition for treating wind-heat toothache |
| FR3078886A1 (en) * | 2018-03-15 | 2019-09-20 | Liu Zhengyu | MEDICAMENT FOR TREATING TOOTHBORNE AND METHOD FOR PREPARING THE SAME |
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