CN103157067A

CN103157067A - Traditional Chinese medicine preparation for treating trigeminal neuralgia

Info

Publication number: CN103157067A
Application number: CN2013101036025A
Authority: CN
Inventors: 孙敏
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-03-16
Filing date: 2013-03-16
Publication date: 2013-06-19

Abstract

The invention discloses a traditional Chinese medicine preparation for treating trigeminal neuralgia. The traditional Chinese medicine holds that the trigeminal neuralgia belongs to a headache, a migraine, a facial pain and the like and results in stagnation leading to pain caused by unlimber lucidity, phlegm stagnation and blood stasis, qi stagnation and blood clotting and meridian repression due to liver Qi stagnation, fire transformation caused by endogenous invasion, blood disturbance led by fire heat, wind fire pathogen complicated by phlegm. Therefore, the invention decocts Chinese holly root of traditional Chinese medicine, hemsley rockvine root, aster ageratoides, forsythia, baical skullcap root, felwort, Japanese ardisia herb, south zucchini, capparis acutifolia, zedoary, abrus herb, homlockleaved moonwort, cornu procaprae gutturosae, white paeony root, caulis polygoni multiflori with water to make a decoction. By clinical experiments, the total effective rate reaches 97.3% which is obviously higher than the control group and no toxic side effect is generated.

Description

A kind ofly treat prosopalgic Chinese medicine preparation

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of prosopalgic Chinese medicine preparation for the treatment of.

Background technology

Trigeminal neuralgia is the commonly encountered diseases of neurosurgery, refers in facial nervi trigeminus areal area, severe pain of short duration, that repeatedly show effect occurs.Its cause of disease is not bright, claims again primary trigeminal neuralgia.Clinical manifestation is that a kind of special trigger stimulates, as touches face or jaw section can excite, and affected nerves of patients with trigeminal neuralgia often dare not be wiped face, feed, and even saliva also dare not be swallowed, thereby affects normal live and work.Therefore this is " the first under heaven pain " bitterly by person, touching difficulty more, aggravation, the course of disease extends, at present doctor trained in Western medicine adopts conventional carbamazepine, the Treatment with Phenytoin used in treatment, several weeks or several months, but due to these two kinds of medicines can cause nausea, weak, even hepatic and renal function is influenced, so can not allow all patients accept.Block therapy (medicine injection of nerve), Percutaneous radiofrequency ablation art therapy, radix sensoria nervi trigemini divide amputation, and certain curative effect is arranged, but after operation, harmful effect are arranged.

Summary of the invention

The purpose of this invention is to provide a kind of prosopalgic Chinese medicine preparation for the treatment of.The traditional Chinese medical science thinks that trigeminal neuralgia belongs to the categories such as " headache ", " migraine ", " prosopodynia ", stagnation of QI due to depression of the liver, strongly fragrant fire-transformation of a specified duration, intimately pneumatic, disturb on wind-fire folder expectorant and cause clearly sun and must not unfold, all YANG-meridians meeting into the head, the essence of five ZANG-organs and six FU-organs China QI and blood is gathered in head on all, all pathogens, wind, fire, phlegm-damp, blood visitor be in meridians, stagnation of phlegm blood stasis, qi stagnation hemagglutination, check meridians, cause " stagnation of QI and blood may bring about pain ".

The objective of the invention is to be achieved through the following technical solutions, the prosopalgic Chinese medicine preparation of this treatment is made by the Chinese medicine of following weight portion: Radix Ilicis Cornutae 5-25 part, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 7-15 part, Herba Asteris Ageratoidis 4-9 part, Fructus Forsythiae 3-14 part, 10 1 15 parts of Radix Scutellariaes, Radix Gentianae 3-6 part, short ground dish 7-10 part, southern hay melon 5-8 part, Radix Capparis Membranaceae 10-20 part, Rhizoma Curcumae 5-9 part, Herba Abri 6-9 part, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 5-7 part, Cornu procaprae gutturosae 3-5 part, Radix Paeoniae Alba 6-15 part, Caulis Polygoni Multiflori 8-10 part.

Preferably, 15 parts of Radix Ilicis Cornutaes, 12 parts of Radix Apioris Fortunei (Radix Lespedezae Buergeri)s, 7 parts of Herba Asteris Ageratoidis, 8 parts of Fructus Forsythiaes, 13 parts of Radix Scutellariaes, 5 parts of Radix Gentianaes, 7 parts of short ground dishes, 6 parts, southern hay melon, 15 parts of Radix Capparis Membranaceaes, 7 parts of Rhizoma Curcumae, 7 parts of Herba Abris, 6 parts of Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., 4 parts of Cornu procaprae gutturosaes, 11 parts of the Radix Paeoniae Albas, 9 parts of Caulis Polygoni Multiflori.

Preparation method is by traditional preparation method, and decocting is made decoction.

In the side: Radix Ilicis Cornutae, Radix Apioris Fortunei (Radix Lespedezae Buergeri) invigorating the liver and kidney, fresh breeze heat, heat-clearing and toxic substances removing, dispelling pathogenic wind and eliminating phlegm, promoting blood circulation and stopping pain; Herba Asteris Ageratoidis, Fructus Forsythiae dispelling wind and heat pathogens, heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation; Radix Scutellariae, Radix Gentianae heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire, cooling blood for hemostasis; Short ground dish, southern hay melon, Radix Capparis Membranaceae, Rhizoma Curcumae dispelling pathogenic wind and eliminating phlegm, promoting blood circulation and hemostasis, removing blood stasis dissipating blood stasis, detumescence circulation of qi promoting, removing food stagnancy pain relieving; Herba Abri, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., Cornu procaprae gutturosae, heat clearing white peony detoxifcation, soothing liver-QI dissipating blood stasis, suppressing the hyperactive liver to relieve the wind syndrome, nourishing blood to suppress the hyperactive liver, slow middle pain relieving; The Caulis Polygoni Multiflori tranquilizing by nourishing the heart, dispelling wind and removing obstruction in the collateral; All medicines share, and play altogether purging liver-fire, reducing phlegm, expelling pathologic wind, promoting blood circulation and stopping pain effect.

Clinical data

1, physical data with clinic case 150 examples of my institute's treatment of in June, 2006～2010 year June, is divided into treatment group and matched group at random, treatment group 75 examples, and male 41 examples wherein, female's 34 examples, in the course of disease 1 week of the shortest person, elder reaches 35 years, age 18-80 year; Matched group 75 examples, male 43 examples wherein, female's 31 examples, in the course of disease 2 weeks of the shortest person, elder reaches 30 years, age 18-75 year; Two groups of Genders, age, the course of disease, state of an illness are learned check there was no significant difference (P＞0.05) by statistics, have comparability.

2,1. criterion of therapeutical effect cures: subjective symptoms all disappears, and not recidivist is observed more than 3 months in drug withdrawal.2. take a turn for the better: subjective symptoms disappears substantially, or the attack times minimizing, pain relief, and drug withdrawal is observed or the rear recurrence in 3 months of healing.3. invalid: symptom is without improvement.

3, Therapeutic Method treatment group patient takes Chinese medicine preparation of the present invention, namely get Radix Ilicis Cornutae 15g, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 12g, Herba Asteris Ageratoidis 7g, Fructus Forsythiae 8g, Radix Scutellariae 13g, Radix Gentianae 5g, short ground dish 7g, southern hay melon 6g, Radix Capparis Membranaceae 15g, Rhizoma Curcumae 7g, Herba Abri 7g, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 6g, Cornu procaprae gutturosae 4g, Radix Paeoniae Alba 11g, Caulis Polygoni Multiflori 9g, decocting becomes decoction, potion, divided early, took for late 2 times every day; The oral Carbamazepine Tablets of matched group, each 0.2g, every day 3 times; Two groups of equal 1 weeks are a course for the treatment of, serve on three courses for the treatment of.

4, the therapeutic outcome treatment is added up curative effect after three courses for the treatment of, and treatment group 75 examples are cured 55 examples, account for 73.3%, and 18 examples that take a turn for the better account for 24.0%, and invalid 2 examples account for 2.7%, total effective rate 97.3%; Matched group 75 examples are cured 45 examples, account for 46.7%, and 19 examples that take a turn for the better account for 25.3%, and invalid 15 examples account for 20.0%; Total effective rate 80.0%; Two groups of comparison treatment group cure rates, total effective rates obviously are better than matched group, and difference has significant (P＜0.05).

5, untoward reaction: untoward reaction does not appear in treatment group.Gastrointestinal dysfunction 4 examples, erythra, hematuria 2 examples, leukopenia 3 examples drowsiness 21 examples appear, in dizzy 17 examples of matched group.

The specific embodiment

Embodiment one: take Radix Ilicis Cornutae 15g, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 12g, Herba Asteris Ageratoidis 7g, Fructus Forsythiae 8g, Radix Scutellariae 13g, Radix Gentianae 5g, short ground dish 7g, southern hay melon 6g, Radix Capparis Membranaceae 15g, Rhizoma Curcumae 7g, Herba Abri 7g, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 6g, Cornu procaprae gutturosae 4g, Radix Paeoniae Alba 11g, Caulis Polygoni Multiflori 9g, by traditional preparation method, decocting is made decoction.

Embodiment two: take Radix Ilicis Cornutae 25g, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 7g, Herba Asteris Ageratoidis 4g, Fructus Forsythiae 14g, Radix Scutellariae 10g, Radix Gentianae 3g, short ground dish 10g, southern hay melon 5g, Radix Capparis Membranaceae 10g, Rhizoma Curcumae 9g, Herba Abri 6g, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 5g, Cornu procaprae gutturosae 3g, Radix Paeoniae Alba 15g, Caulis Polygoni Multiflori 10g, by traditional preparation method, decocting is made decoction.

Embodiment three: take Radix Ilicis Cornutae 5g, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 15g, Herba Asteris Ageratoidis 9g, Fructus Forsythiae 3g, Radix Scutellariae 15g, Radix Gentianae 6g, short ground dish 7g, southern hay melon 8g, Radix Capparis Membranaceae 20g, Rhizoma Curcumae 5g, Herba Abri 6g, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 7g, Cornu procaprae gutturosae 4g, Radix Paeoniae Alba 11g, Caulis Polygoni Multiflori 9g, by traditional preparation method, decocting is made decoction.

Claims

1. the prosopalgic Chinese medicine preparation for the treatment of, is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: Radix Ilicis Cornutae 5-25 part, Radix Apioris Fortunei (Radix Lespedezae Buergeri) 7-15 part, Herba Asteris Ageratoidis 4-9 part, Fructus Forsythiae 3-14 part, Radix Scutellariae 10-15 part, Radix Gentianae 3-6 part, short ground dish 7-10 part, southern hay melon 5-8 part, Radix Capparis Membranaceae 10-20 part, Rhizoma Curcumae 5-9 part, Herba Abri 6-9 part, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 5-7 part, Cornu procaprae gutturosae 3-5 part, Radix Paeoniae Alba 6-15 part, Caulis Polygoni Multiflori 8-10 part.

2. a kind of prosopalgic Chinese medicine preparation for the treatment of according to claim 1 is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: 15 parts of Radix Ilicis Cornutaes, 12 parts of Radix Apioris Fortunei (Radix Lespedezae Buergeri)s, 7 parts of Herba Asteris Ageratoidis, 8 parts of Fructus Forsythiaes, 13 parts of Radix Scutellariaes, 5 parts of Radix Gentianaes, 7 parts of short ground dishes, 6 parts, southern hay melon, 15 parts of Radix Capparis Membranaceaes, 7 parts of Rhizoma Curcumae, 7 parts of Herba Abris, 6 parts of Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., 4 parts of Cornu procaprae gutturosaes, 11 parts of the Radix Paeoniae Albas, 9 parts of Caulis Polygoni Multiflori.