CN101554461B - Medicine for treating psoriasis and preparation method of capsule thereof - Google Patents

Abstract

The invention belongs to a traditional Chinese medicine compound preparation for treating autoimmune disease and the preparative technical field, relating to a medicine for treating the psoriasis and a preparation method of capsule thereof. The medicine for treating the psoriasis comprises a monarch drug, a ministerial drug, a adjuvant drug, and a conductant drug; wherein the monarch drug is balsamine; the ministerial drug is chinaroot greenbrier and ramulus euonymi; the adjuvant drug is oldenlandia diffusa, Chinese violet, creat, angelica, oyster, and malt extract; the conductant drug is liqurice. The raw materials are blended and prepared into capsule preparation forms according to the certain mixture ratio. When being taken orally, the capsule can remove pathogenic heat from blood, relieves exterior syndrome, dispels scraps, removes ringworm, relieves itching, balances organism immunologic function and can be used for treating various psoriasis. The raw materials of the invention are pure natural botanical drugs, are safe and easy to obtain; the method is simple and easy to operate, does not draw into toxic substances, has low cost, and has very important significance in the research and development of traditional Chinese medicine for treating the psoriasis.

Description

Psoriatic medicine of a kind of treatment and capsular method for preparing thereof

Technical field

The invention belongs to the compound Chinese medicinal preparation and the preparing technical field of treatment autoimmune disease, relate to psoriatic medicine of a kind of treatment and capsular method for preparing thereof.

Background technology

Psoriasis is a kind of outbreak repeatedly, be characteristic with epidermis propagation and inflammation, FFI erythroderma desquamativum is commonly called as " psoriasis ", its cause of disease is relevant with heredity, infection, allergy, dysbolismus and autoimmune etc.This disease course of disease is long, and outward appearance is ugly, and touching difficulty heals, and the course of disease later stage can be invaded multiple internal organs, brings very big injury and be called " not dead cancer " by department of dermatologry for patient's body and mind.

The present clinical psoriatic method of special efficacious therapy of still not having.Traditional medicine has: immunosuppressant, glucocorticoid, tar class medicine.Immunosuppressant (methotrexate, cyclosporin) is used to treat nearly 70 years history of psoriasis; But use that immunosuppressant can cause headache, shiver with cold, heating, tired, stomachache, feels sick, vomiting, dizziness, pruritus, alopecia, urticaria, ecchymosis, untoward reaction such as photosensitive, make its clinical practice receive certain restriction.17-hydroxy-11-dehydrocorticosterone is to use the widest psoriasis medicine, has antiproliferative and immunosuppressive action are arranged, and it can alleviate the inflammation at skin lesion position, and relieving itch reduces squama.But the metabolism disorder that the life-time service hormone causes, bring out or increase the weight of untoward reaction such as infection, digestive system complication, cardiovascular complications, osteoporosis and vertebral compression property fracture.Coal tar oils medicine also is to treat psoriatic common drug at present, and coal tar can reduce the mitosis of epidermis cell, the formation of squama and the sebum secretion of sebaceous gland, and has antiinflammatory action, but also has certain side effect.At present,, often have toxic and side effects, and relapse rate is high though psoriatic western medicine therapy is many.Chinese medicine is demonstrating certain advantage aspect treatment psoriasis and the recurrence of prevention psoriasis.

The inventor has developed a kind of treatment psoriasis Chinese medicine compound in earlier stage, and has done clinical observation, male 44 examples among the patient, women 36 examples to 80 routine psoriatics; 16～65 years old age, 33 years old mean age, the course of disease 3 days～14 days; Be and just send out the person, do not use any medicine, directly come outpatient service prescription on individual diagnosis person.This Chinese medicine compound course of treatment is 30 days.The treatment standard that adopts is following: recovery from illness: treatment pimple 2～3 course of treatment or speckle are lived in retirement, and leave pigmentation, or hypopigmentation do not have new breakout, and no gargalesthesia is followed up a case by regular visits to not have in 1 year and recurred; Take a turn for the better: pimple or speckle attenuation, body of the tongue is light red, and squama reduces, and the infringement of minority New Development is arranged, no isomorphic response, gargalesthesia alleviates; Invalid: as not have obviously change before and after the treatment.Result of study shows: among the 80 routine patients of this compound of Chinese medicine, cure 51 examples and account for 63.75%; 22 examples that take a turn for the better account for 27.5%; Invalid 7 examples account for 8.75%; Total effective rate: 91.25%.We have also carried out this medicine untoward reaction research in addition, do not have 1 example in the 80 routine treatment groups and side effect occurs, are tried liver function after patient's medication, kidney merit and the equal no abnormality seen of blood routine examination.

Summary of the invention

The objective of the invention is provides a kind of Chinese medicine that can effectively treat psoriatic high-efficiency low-toxicity on the treatment psoriasis Chinese medicine compound basis of development in early stage.

According to traditional Chinese medical science traditional theory, Flos Impatientis has the effect of removing pathogenic heat from blood and toxic substance from the body; Rhizoma Smilacis Chinensis, Ramulus Euonymi have the effect of blood circulation promoting and blood stasis dispelling, dispelling wind for relieving itching; The effect that Herba Hedyotidis Diffusae, Herba Violae, Herba Andrographis have removing heat from blood, heat clearing away, detoxify, dispel the wind; Radix Angelicae Sinensis, Concha Ostreae, maltose, Radix Glycyrrhizae have the effect of hepatoprotective, protection gastric mucosa, coordinating the actions of various ingredients in a prescription, more than all medicines share the effect of playing heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation, dispelling wind for relieving itching altogether.

Technical scheme of the present invention is: the psoriatic medicine of a kind of treatment, form by monarch drug, ministerial drug, adjuvant drug and messenger drug, and wherein monarch drug is a Flos Impatientis; Ministerial drug is Rhizoma Smilacis Chinensis, Ramulus Euonymi; Adjuvant drug is Herba Hedyotidis Diffusae, Herba Violae, Herba Andrographis, Radix Angelicae Sinensis, Concha Ostreae, maltose; Messenger drug is a Radix Glycyrrhizae.Each crude drug percentage by weight is following:

Flos Impatientis 20%

Rhizoma Smilacis Chinensis 10%

Ramulus Euonymi 10%

Herba Hedyotidis Diffusae 10%

Herba Violae 10%

Herba Andrographis 10%

Radix Angelicae Sinensis 10%

Concha Ostreae 10%

Maltose 5%

Radix Glycyrrhizae 5%

It is following to prepare a kind of method of treating psoriatic medicament capsule:

Take by weighing ten flavor crude drug by above-mentioned proportion, soaked 1 hour after cleaning, decoct then 3 times, the time was respectively 1.5,1.0,0.5 hours, merged three times decoction liquor; Filter, filtrating is concentrated into the thick paste shape, and oven dry is pulverized; Cross the 80-100 mesh sieve, mixing, sterilization incapsulates.

The invention has the beneficial effects as follows: this compound Chinese medicinal preparation for oral administration can clearing away heat and cooling blood, the dandruff removing of inducing sweat, remove tinea and relieving itching, balancing machine body immunity function, can be used for treating various psoriasises.Raw material is a pure natural plant medicines, and safety is easy to get, and method is simple to operation, does not introduce noxious substance, and is with low cost, in the psoriatic Chinese medicine research exploitation of treatment, has very important significance.

The specific embodiment

The psoriatic medicine of a kind of treatment is made up of monarch drug, ministerial drug, adjuvant drug and messenger drug.Wherein monarch drug is to have Chinese medicine Flos Impatientis 20 grams of regulating immunologic function; Ministerial drug is Rhizoma Smilacis Chinensis 10 grams, Ramulus Euonymi 10 grams; Adjuvant drug is Herba Hedyotidis Diffusae, Herba Violae, Herba Andrographis, Radix Angelicae Sinensis, each 10 gram of Concha Ostreae, maltose 5 grams; Messenger drug is Radix Glycyrrhizae 5 grams.After above-mentioned ten flavor Chinese medicines are cleaned, soaked 1 hour, decoct then 3 times, the time was respectively 1.5,1.0,0.5 hours.Merge three times decoction liquor, filter, filtrating is concentrated into the thick paste shape, and oven dry is pulverized, and crosses the 80-100 mesh sieve, mixing, and sterilization incapsulates, and promptly gets.

Claims (2)

1. the psoriatic medicine of treatment is characterized in that this medicine is processed by Flos Impatientis, Rhizoma Smilacis Chinensis, Ramulus Euonymi, Herba Hedyotidis Diffusae, Herba Violae, Herba Andrographis, Radix Angelicae Sinensis, Concha Ostreae, maltose, Radix Glycyrrhizae; Each crude drug percentage by weight is following:

2. prepare the described a kind of method of treating psoriatic medicine of claim 1, it is characterized in that this method is:

Take by weighing ten flavor crude drug by above-mentioned proportion, soaked 1 hour after cleaning, decoct then 3 times, the time was respectively 1.5,1.0,0.5 hours, merged three times decoction liquor; Filter, filtrating is concentrated into the thick paste shape, and oven dry is pulverized; Cross the 80-100 mesh sieve, mixing, sterilization incapsulates.