CN103432265A - Traditional Chinese medicinal composition preparation for treating fever in children and preparation method thereof - Google Patents
Traditional Chinese medicinal composition preparation for treating fever in children and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicinal composition preparation for treating fever in children and a preparation method thereof. The traditional Chinese medicinal composition comprises the following raw materials in parts by weight: 10-15 parts of platycodon grandiflorum, 25-35 parts of herba houttuyniae, 25-35 parts of perilla leaf and 8-12 parts of liquorice. The preparation method comprises the following steps of: decocting platycodon grandiflorum, herba houttuyniae, perilla leaf and liquorice with water twice, filtering, and concentrating the filtrate to half of the filtrate volume to obtain a concentrated solution; filtering the decoction dregs, mixing the filtrates, and concentrating the filtrate to half of the filtrate volume to obtain a concentrated solution; concentrating the concentrated solution into dense extract of which the relative density at 80 DEG C is tested to be 1.21-1.25; moving into an oven, baking at 50-70 DEG C until the moisture content is lower than 5 percent, and taking out, preparing into capsules, tablets, decoctions, granules or oral solutions according to the prior art in the field. The traditional Chinese medicinal composition preparation is small in dosage, takes effect quickly, hardly causes side effects, capable of quickly relieving clinical symptom, and has good treatment effect. The raw materials can be purchased easily and low in price; the traditional Chinese medicinal composition preparation is convenient to manufacture and is worthy of popularization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicinal composition preparation for the treatment of fever of children and preparation method thereof, belong to tcm field.
Background technology
Heating is one of modal symptom of infantile common cold disease, is the defensive reaction of health that various diseases causes, heating refers to pathologic fervescence, or conscious heating is main symptom.Heating is a kind of general reaction of human body to virulence factor, is clinical utmost point common sympton, in general, heat production with heat radiation under the adjusting of heat center, make body temperature maintain 37 ℃ upper and lower, every day, body temperature poorly was no more than 1 ℃.The heat production that any reason causes>heat radiation, will cause fervescence, be referred to as heating, the cause of disease of fever of children is a lot, can be divided into clinically infectious and non-infectious, common with infectivity, infection comprises antibacterial infection and viral infection and fungal infection etc., as caught a cold etc., it is the modal cause of disease, need the at first clear and definite cause of disease for heating, for the cause of disease, processed, when fervescence, (38 ℃～39 ℃) its health is responsible for engulfing the leukocyte phagocytic activity reinforcement of antibacterial, heating surpasses 38 degree and will attract great attention, easily cause children with high fever induced convulsions during hyperpyrexia, so must control body temperature, it is mainly the method that adopts drug cooling and Physical temperature-lowering, the Chinese medicine fever of children has certain advantage, it is mainly the toxic and side effects that there is no Western medicine, , the Chinese medicine preparation that some treatment fever of children also occurred in the market, but the Chinese medicine preparation of these treatment fever of children has certain curative effect to children's, but effective percentage is not good, and pharmaceutical preparation is many.
Summary of the invention
For the problem of above-mentioned existence, the invention provides a kind of Chinese medicinal composition preparation for the treatment of fever of children and preparation method thereof
The technical solution adopted in the present invention is:
A kind of Chinese medicinal composition preparation for the treatment of fever of children comprises the raw material of following weight portion:
Radix Platycodonis 10-15 part, Herba Houttuyniae 25-35 part, Folium Perillae 25-35 part, Radix Glycyrrhizae 8-12 part.
As technique scheme further preferably, described Chinese medicinal composition preparation comprises the raw material of following weight portion:
12 parts of Radix Platycodoniss, 30 parts of Herba Houttuyniae, 30 parts of Folium Perillae, 10 parts, Radix Glycyrrhizae.
The present invention treats the Chinese medicinal composition preparation of fever of children, and dosage form is capsule, tablet, decoction, granule or oral solutions.
A kind of preparation method for the treatment of the Chinese medicinal composition preparation of fever of children comprises the following steps:
A, proportionally get each composition of raw material and mix, decoct with water 30 minutes water decoction.
B, Radix Platycodonis, Herba Houttuyniae, Folium Perillae, Radix Glycyrrhizae are decocted with water to twice, filter, filtrate is concentrated into 1/2 of filtrate volume, obtains concentrated solution.
The gained medicinal residues filter, and merging filtrate, be concentrated into 1/2 of filtrate volume, obtains concentrated solution.
C, above-mentioned concentrated solution are concentrated into 80 ℃ of thick extractum that record relative density 1.21～1.25.The shift-in baking oven, dry to moisture lower than 5% for 50-70 ℃, takes out
Controlling into capsule, tablet, decoction, granule or oral solutions by state of the art gets final product.
In above raw material,
Radix Platycodonis bitter in the mouth, suffering, property is flat.Return lung meridian.Effect lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus.Radix Platycodonis is still regulated the flow of vital energy, invigorates blood circulation, is helped digestion, sedative action.Research Radix Platycodonis has calmness, analgesia, refrigeration function now, and antibacterial action is arranged, and multiple coccus, bacillus and acrothesium floccosum are had to inhibitory action, and antiinflammatory and immunological enhancement are arranged.
The Herba Houttuyniae acrid in the mouth, cold nature, have heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; The effect of inducing diuresis for treating stranguria syndrome, treatment lung abscess vomiting pus; The expectorant dyspnea of heat type is coughed; Larynx; Hematodiarrhoea; Be used for the treatment of lung-heat, expectorant heat, lung abscess, cough the key medicine of vomiting bloody pus.Also can be used for pathopyretic ulcer, damp-heat gonorrhoea, damp-heat dysentery.
The Folium Perillae effect cold expelling that induces sweat, relieving QI stagnancy in the stomach.For anemofrigid cold, the cough vomiting and nausea, vomiting during pregnancy, the fish Eriocheir sinensis is poisoning.The Folium Perillae exterior cold of faling apart, diaphoresis power is stronger, for wind and cold table disease, sees aversion to cold, heating, the disease such as lossless
Radix Glycyrrhizae effect invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The traditional Chinese medical science thinks that fever of children is mainly yang-energy stasis in vivo, can not normally declare to have carried out the coffin upon burial.Because of children's's YANG often being in excess, the physiological characteristics of YIN often being in shortage, a lot of acute and chronic disease cards all have the symptom of heating.Therefore Zhu Danxi: all children's are ill all hot.Wang Ken party: children's's disease, only heat is in the majority." A complete work on Pediatrics, a collection and arrangement of the chief contents from ancient pediatrics, written by Chen Fuzheng " will generate heat and simply be divided into exterior heat interior-heat deficiency-heat excess-heat fever of children card and can be divided into two large classes: fever caused by exogenous pathogens and interior syndrome generate heat.
The present invention's application Folium Perillae cold expelling that induces sweat, reach yang-energy thoroughly. and the Herba Houttuyniae heat-clearing and toxic substances removing, lung heat clearing is defended the Radix Platycodonis lung qi dispersing and is eliminated the phlegm, regulates the flow of vital energy and calm the nerves. and the Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing four medicines coordinate plays the heat clearing away of inducing sweat, the merit that lung qi dispersing is regulated the flow of vital energy altogether
The present invention compared with prior art, has the following advantages: monarch of the present invention, minister, helps, makes respectively to execute its effect, there is medication few, and instant effect, side effect is little, the rapid recovery clinical symptoms, therapeutic effect is good.Raw material of the present invention is bought convenient, and low price is easy to make, is worthy of popularization.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1,
A kind of treat fever of children Chinese medicinal composition preparation, described medicine is made by the raw material of following weight portion:
10 parts of Radix Platycodoniss, 25 parts of Herba Houttuyniae, 25 parts of Folium Perillae, 8 parts, Radix Glycyrrhizae.
The present invention treats the Chinese medicinal composition preparation of fever of children, and dosage form is capsule, decoction, tablet, granule or oral solutions.
Preparation method comprises the following steps:
A, proportionally get each composition of raw material and mix, decoct with water 30 minutes water decoction.
B, Radix Platycodonis, Herba Houttuyniae, Folium Perillae, Radix Glycyrrhizae are decocted with water to twice, filter, filtrate is concentrated into 1/2 of filtrate volume, obtains concentrated solution.
The gained medicinal residues filter, and merging filtrate, be concentrated into 1/2 of filtrate volume, obtains concentrated solution.
C, above-mentioned concentrated solution are concentrated into 80 ℃ of thick extractum that record relative density 1.21～1.25.The shift-in baking oven, dry to moisture lower than 5% for 50-70 ℃, takes out
Controlling into capsule, tablet, granule or oral solutions by state of the art gets final product.
Embodiment 2,
A kind of treat fever of children Chinese medicinal composition preparation, described medicine is made by the raw material of following weight portion:
12 parts of Radix Platycodoniss, 30 parts of Herba Houttuyniae, 30 parts of Folium Perillae, 10 parts, Radix Glycyrrhizae.
Preparation method is identical with embodiment 1
Embodiment 3,
A kind of treat fever of children Chinese medicinal composition preparation, described medicine is made by the raw material of following weight portion:
15 parts of Radix Platycodoniss, 35 parts of Herba Houttuyniae, 35 parts of Folium Perillae, 12 parts, Radix Glycyrrhizae.
Preparation method is identical with embodiment 1.
Contrast test:
Criterion of therapeutical effect with reference to<<traditional Chinese medical science Pediatrics Department Illnesses Diagnoses criterion of therapeutical effect draft: 37.5～38 ℃ of axil temperature are low grade fever, 38.1～39 ℃ is the moderate heating, 39.1～40.5 ℃ is high heat,>40.5 ℃ is excessive heat, include therapeutic domain in 38.1～39 ℃. produce effects: the oral drugs body temperature that generates heat after two hours is normal, and lower than 37.5 ℃ effectively: the oral drugs improvement of generate heat after two hours is still invalid higher than 37.5 ℃: oral drugs generate heat unchanged or increase after two hours
Choosing 400 routine fever of children patients (coughs comprising acute/chronic bronchitis, upper respiratory tract infection, pneumonia, viral influenza patient), choose at random 300 examples as treatment group, other 100 examples as a control group, wherein 300 routine patients are divided into treatment group 1, treatment group 2 and treatment group 3, the 100 routine patients that each treatment group treatment is chosen at random, treatment group 1 is used the water decoction of the embodiment of the present invention 1 preparation to be treated, treatment group 2 is used the water decoction of the embodiment of the present invention 2 preparations to be treated, treatment group 3 is used the water decoction of the embodiment of the present invention 3 preparations to be treated.
The patient of matched group adopts conventional application ibuprofen suspension oral, for the cause of disease, is treated simultaneously.Treatment group adds medicine water decoction of the present invention, for the cause of disease, is treated simultaneously.
Therapeutic outcome is as following table:
From above tables of data, can find out, treatment group effective percentage obvious effective rate is apparently higher than matched group, and the cure rate effective percentage for the treatment of group 2 is higher than all the other treatment groups, and treatment group 2 prescriptions are the most effective in sum.
Claims (4)
1. a Chinese medicine composition for the treatment of fever of children, it is characterized in that: described medicine comprises the raw material of following weight portion: Radix Platycodonis 10-15 part, Herba Houttuyniae 25-35 part, Folium Perillae 25-35 part, Radix Glycyrrhizae 8-12 part.
2. the Chinese medicine composition for the treatment of fever of children as claimed in claim 1, it is characterized in that: described Chinese medicine comprises the raw material composition of following weight portion: 12 parts of Radix Platycodoniss, 30 parts of Herba Houttuyniae, 30 parts of Folium Perillae, 10 parts, Radix Glycyrrhizae.
3. treat as claimed in claim 1 or 2 the Chinese medicine composition of fever of children, it is characterized in that: the Chinese medicinal composition preparation dosage form is capsule, tablet, decoction, granule or oral solutions.
4. a preparation method for the treatment of the Chinese medicinal composition preparation of fever of children comprises the following steps:
A, proportionally get each composition of raw material and mix, decoct with water 30 minutes water decoction.
B, Radix Platycodonis, Herba Houttuyniae, Folium Perillae, Radix Glycyrrhizae are decocted with water to twice, filter, filtrate is concentrated into 1/2 of filtrate volume, obtains concentrated solution.
The gained medicinal residues filter, and merging filtrate, be concentrated into 1/2 of filtrate volume, obtains concentrated solution.
C, above-mentioned concentrated solution are concentrated into 80 ℃ of thick extractum that record relative density 1.21～1.25.The shift-in baking oven, dry to moisture lower than 5% for 50-70 ℃, takes out, and controls into capsule, tablet, decoction, granule or oral solutions by state of the art and get final product.
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| CN105168582A (en) * | 2015-10-12 | 2015-12-23 | 长沙秋点兵信息科技有限公司 | Traditional Chinese medicine composition for children cold and preparation method thereof |
| CN105535927A (en) * | 2016-01-29 | 2016-05-04 | 山东中海制药有限公司 | Medicine used for treating influenza, upper respiratory infection and viral pneumonia |
| CN109602875A (en) * | 2019-01-28 | 2019-04-12 | 帅云飞 | A kind of Chinese medicine composition that treating fever in children, preparation method and applications |
| CN111328899A (en) * | 2020-02-25 | 2020-06-26 | 深圳神思汉方生物科技有限公司 | Orange, cattail and perilla herb substituted tea and preparation method thereof |
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| CN109602875A (en) * | 2019-01-28 | 2019-04-12 | 帅云飞 | A kind of Chinese medicine composition that treating fever in children, preparation method and applications |
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| CN111328899A (en) * | 2020-02-25 | 2020-06-26 | 深圳神思汉方生物科技有限公司 | Orange, cattail and perilla herb substituted tea and preparation method thereof |
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| CN103432265B (en) | 2016-08-10 |
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