CN102114225A - Traditional Chinese medicine for treating gout of diabetes patient - Google Patents
Traditional Chinese medicine for treating gout of diabetes patient Download PDFInfo
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Abstract
Description
技术领域technical field
本发明属于治疗糖尿病的中药领域。The invention belongs to the field of traditional Chinese medicine for treating diabetes.
背景技术Background technique
糖尿病患者免疫力低下,代谢紊乱,并发痛风者有一定数量。目前旨在治疗糖尿病痛风的中药方面,存在一些不足:一是效果不够明显,二是见效比较迟缓,以致许多这种疾病的患者长期受着关节红、肿、热、痛的折磨,很是痛苦,患者及家属对此不满意。Diabetic patients have low immunity, metabolic disorders, and a certain number of gout patients. At present, there are some deficiencies in traditional Chinese medicine aimed at treating diabetic gout: one is that the effect is not obvious enough, and the other is that the effect is relatively slow, so that many patients with this disease suffer from joint redness, swelling, heat, and pain for a long time, which is very painful. , patients and their families are not satisfied with this.
针对上述提出的问题,本发明提供一种治疗糖尿病痛风的中药,它能解决以往此类中药治疗中效果不够明显,见效比较迟缓的问题,效果好、见效快,具有效果显著,药效确切,见效较快的优点。In view of the problems raised above, the present invention provides a traditional Chinese medicine for treating diabetic gout, which can solve the problem that the effect of traditional Chinese medicines in the past is not obvious enough, and the effect is relatively slow. The advantage of quicker results.
发明内容Contents of the invention
本发明是通过以下技术方案来实现的:The present invention is achieved through the following technical solutions:
1、一种治疗糖尿病痛风的中药,采用中药原料制备,配方为(按重量比):1. A traditional Chinese medicine for treating diabetic gout, which is prepared from raw materials of traditional Chinese medicine, and the formula is (by weight):
莪术4——12份 土茯苓6——18份 灵芝6——18份Curcuma 4—12 parts Smilax 6—18 parts Ganoderma lucidum 6—18 parts
三七3——9份 萆薢5——15份 当归6——18份Panax notoginseng 3——9 parts Angelica 6——18 parts
海金沙6——18份Haijinsha 6 - 18 servings
这种治疗糖尿病痛风的中药是由下列方法制成的:This traditional Chinese medicine for treating diabetic gout is made by the following method:
(1)按上述重量比,将灵芝用水提醇沉法提取灵芝多糖,工艺流程如下:将灵芝破碎成颗粒状,过40目筛→用1:20的热水(95℃)浸提→浸提液减压、浓缩→用3倍体积的95%乙醇混合、静置10—12小时、离心→加75%的乙醇,沉淀多糖→烘干得灵芝多糖提取物细粉;(1) According to the above weight ratio, extract Ganoderma lucidum polysaccharides from Ganoderma lucidum with water extraction and alcohol precipitation method, the process is as follows: crush Ganoderma lucidum into granules, pass through a 40-mesh sieve → leaching with 1:20 hot water (95°C) → leaching Extract the liquid under reduced pressure, concentrate → mix with 3 times the volume of 95% ethanol, let stand for 10-12 hours, centrifuge → add 75% ethanol, precipitate polysaccharide → dry to obtain fine powder of Ganoderma lucidum polysaccharide extract;
(2)按上述重量比,将莪术、土茯苓、萆薢、当归、海金沙经常规水提取工艺提取,制成提取物浸膏细粉;(2) According to the above weight ratio, extract the zedoary, Smilax tuckahoe, Chinese herb, angelica, and Haijinsha through the conventional water extraction process to make the extract powder;
(3)按上述重量比,将三七研成细粉,与上述(1)、(2)两种提取物细粉混合,搅拌均匀,制成中药颗粒剂、胶囊剂、片剂。(3) Grind notoginseng into fine powder according to the above weight ratio, mix with the fine powder of the above two kinds of extracts (1) and (2), stir evenly, and make traditional Chinese medicine granules, capsules, and tablets.
本发明根据民间传统配方,根据中医扶正培本、活血化瘀的理论,精心研制而成。我们研究认为,凡糖尿病痛风者皆有一个免疫力低下问题,或先天禀赋不足,或年迈脏器日衰,加之不节饮食,恣啖肥甘厚味,浊毒随之而生,滞留血中,瘀结为患。治当以增强免疫力为重点,益气养血,活血化瘀,清利湿热,通淋排石。本方之中灵芝、当归扶正培本,益气养血,增强机体免疫力,免疫力的清除作用可把血液中多余的脂质、尿酸等排出体外,这是治疗本病的关键;伍以莪术、三七活血化瘀,止关节之痛;佐以土茯苓、萆薢清热利湿,两药皆有除湿解毒利关节之功;辅以金海沙甘寒清利,主除血分湿热而利尿通淋排石。诸药配伍,相得益彰,共奏扶正培本,益气养血,活血化瘀,清热利湿,通淋排石之功,效果好,见效快,具有效果显著,药效确切,见效较快的优点。The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. According to our research, all diabetic gout patients have a problem of low immunity, or lack of congenital endowment, or aging organs, coupled with improper diet, indulge in fat, sweet and delicious food, turbidity and poison will be born and stay in the blood , stasis infested. The treatment should focus on enhancing immunity, replenishing qi and nourishing blood, promoting blood circulation and removing blood stasis, clearing damp and heat, clearing stranguria and expel stones. Ganoderma lucidum and Angelica Fuzheng Peiben in this prescription can nourish qi and blood, enhance the body's immunity, and the elimination of immunity can excrete excess lipids and uric acid in the blood, which is the key to the treatment of this disease; Curcuma and Panax notoginseng promote blood circulation and remove blood stasis, relieve joint pain; supplemented with Smilax tuckahoe and Bixie to clear away heat and dampness, both of them can dehumidify, detoxify and benefit joints; supplemented with Jinhaisha sweet and cold, mainly remove dampness and heat in blood, diuresis and relieve stranguria row of stones. All the medicines are compatible and complement each other. They play the role of strengthening the body, nourishing qi and nourishing blood, promoting blood circulation and removing blood stasis, clearing away heat and dampness, dredging stranguria and removing stones. The effect is good and quick. advantage.
具体实施方式Detailed ways
通过以下实施方式对本发明做具体说明:The present invention is specifically described by the following embodiments:
1、取以下配方(重量按克为单位):1. Take the following formula (weight in grams):
莪术50克 土茯苓70克 灵芝70克Curcuma 50g 70g Ganoderma lucidum 70g
三七30克 萆薢60克 当归70克Panax notoginseng 30 grams Angelica sinensis 60 grams Angelica sinensis 70 grams
海金沙70克Sea Sands 70g
按规定重量,用水提醇沉法将灵芝进行提取;用常规水提取工艺将莪术、土茯苓、萆薢、当归、海金沙提取,共制成提取物细粉78克,将三七研成细粉,与上述提取物细粉混合,搅拌均匀,制成细小颗粒,装入0号胶囊,制成中药胶囊385粒,每粒胶囊内含中药细粉及提取物0.28克。According to the specified weight, extract Ganoderma lucidum with water extraction and alcohol precipitation method; use conventional water extraction process to extract Curcuma, Smilax, Radix, Angelica, and Haijinsha, and make a total of 78 grams of extract fine powder, and grind Sanqi into fine powder , mixed with the above-mentioned extract fine powder, stirred evenly, made into fine particles, packed into No. 0 capsules, and made into 385 Chinese medicine capsules, each capsule containing Chinese medicine fine powder and 0.28 grams of extract.
2、取以下配方(重量按克为单位):2. Take the following formula (the weight is in grams):
莪术80克 土茯苓130克 灵芝130克80g curcuma 130g ganoderma lucidum 130g
三七60克 萆薢100克 当归130克Panax notoginseng 60 grams Angelica sinensis 100 grams Angelica sinensis 130 grams
海金沙130克Sea Sands 130g
按上述同样的方法,制成中药胶囊714粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 714 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.
3、取以下配方(重量按克为单位):3. Take the following formula (the weight is in grams):
莪术120克 土茯苓180克 灵芝180克Curcuma 120 grams Smilax Smilax 180 grams Ganoderma lucidum 180 grams
三七80克 萆薢150克 当归180克Panax notoginseng 80 grams Angelica sinensis 150 grams Angelica sinensis 180 grams
海金沙180克Sea Sands 180g
按上述同样的方法,制成中药胶囊992粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 992 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.
4、取以下配方(按重量比):4. Take the following formula (by weight ratio):
莪术4份 土茯苓6份 灵芝5份4 parts Curcuma 6 parts Smilax Smilax 5 parts Ganoderma lucidum
三七3份 萆薢5份 当归5份3 servings of Panax notoginseng 5 servings of Angelica sinensis 5 servings
海金沙6份Sea Sands 6 servings
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.
5、取以下配方(按重量比):5. Take the following formula (by weight):
莪术10份 土茯苓15份 灵芝15份Curcuma 10 parts Smilax 15 parts Ganoderma lucidum 15 parts
三七7份 萆薢12份 当归15份7 servings of Panax notoginseng 12 servings of Angelica sinensis 15 servings
海金沙15份Sea Sands 15 copies
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.
临床资料:clinical information:
本发明以中医糖尿病痛风为例,经7例临床观察。选择中医诊断糖尿病痛风为标准:糖尿病患者虚损严重,肢体无力;四肢远端关节——跖趾关节、踝、肘、手腕、膝关节反复发作关节炎,发作时关节剧烈疼痛、红肿、发热、压痛;体内有痛风石,在耳轮、跖趾、手指、肘等关节处易发生自行破溃,排出白色粉末状物,形成溃疡,不易愈合。如上症状,即可确诊。在确诊观察的对象中,全部是男性7例,无其它严重疾病,年龄为49岁—79岁,平均年龄62.7岁。The present invention takes TCM diabetic gout as an example, through 7 clinical observations. Diabetic gout is selected as the standard for diagnosis of diabetic gout in traditional Chinese medicine: diabetic patients suffer from serious weakness and weakness of limbs; the distal joints of the extremities - metatarsophalangeal joints, ankles, elbows, wrists, and knees recurrently suffer from arthritis, with severe joint pain, redness, fever, Tenderness; there are tophi in the body, and the helix, metatarsophalangeal, fingers, elbows and other joints are prone to self-rupture, and white powdery matter is discharged, forming ulcers, which are not easy to heal. The above symptoms can be diagnosed. Among the confirmed observation objects, all 7 were males, without other serious diseases, ranging in age from 49 to 79 years old, with an average age of 62.7 years.
疗效判定:Judgment of curative effect:
1、显效:体质增强,肢体有力;关节红、肿、热、痛明显减轻;关节溃疡痊愈,不见痛风石排出。1. Significant effect: Physical fitness is enhanced, limbs are strong; joint redness, swelling, heat, and pain are significantly relieved; joint ulcers are healed, and tophi is not discharged.
2、有效:体质增强,关节疼痛、溃疡等症状有所缓解。2. Effective: Physical fitness is enhanced, and symptoms such as joint pain and ulcers are relieved.
3、无效:病症无变化。3. Ineffective: no change in symptoms.
临床实验时,除降糖药照常服用外,停服其它药物和保健营养品。服用本发明中药胶囊,观察3个月为一个疗程。服用方法:每日2次,每次4粒胶囊,每粒胶囊内含中药细粉及提取物0.28克,饭后温开水送服,1个月后症状即有缓解,服用3个月后,症状明显改善。临床实验的7人中,显效3人,有效3人,无效1人,总有效率85.7%。During the clinical trial, except for the hypoglycemic drugs, stop taking other drugs and health nutrition products. Take Chinese medicine capsule of the present invention, observe 3 months and be a course of treatment. Dosing method: 2 times a day, 4 capsules each time, each capsule contains 0.28 grams of fine powder and extract of traditional Chinese medicine, take it with warm water after meals, the symptoms will be relieved after 1 month, and after 3 months of taking, Symptoms improved significantly. Among the 7 people in the clinical trial, 3 were markedly effective, 3 were effective, and 1 was ineffective, with a total effective rate of 85.7%.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102380073A (en) * | 2011-07-23 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic gout |
| CN102380069A (en) * | 2011-09-27 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetes and gout |
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- 2010-12-24 CN CN2010106042870A patent/CN102114225A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102380073A (en) * | 2011-07-23 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic gout |
| CN102380069A (en) * | 2011-09-27 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetes and gout |
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Application publication date: 20110706 |