CN105055614A - Preparation process of Chinese herbal medicine concentrated medicine for treating livestock and poultry intestinal diseases - Google Patents
Preparation process of Chinese herbal medicine concentrated medicine for treating livestock and poultry intestinal diseases Download PDFInfo
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- CN105055614A CN105055614A CN201510522324.6A CN201510522324A CN105055614A CN 105055614 A CN105055614 A CN 105055614A CN 201510522324 A CN201510522324 A CN 201510522324A CN 105055614 A CN105055614 A CN 105055614A
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Abstract
The invention relates to a preparation process of Chinese herbal medicine concentrated medicine for treating livestock and poultry intestinal diseases. Selected medicinal materials are subjected to the processes of soaking, first digestion, first filtering, second digestion, second filtering, third digestion, third filtering, combining, concentrating and storage to obtain the concentrated medicine. The preparation process is based on the theory of traditional Chinese medicine and refers to modern pharmacological research results, and the Chinese herbal medicine concentrated medicine is obtained based on the pure traditional Chinese medicine matching principle, has the effects of clearing away heat and toxic materials, eliminating dampness and stopping dysentery, prompting blood circulation to remove blood stasis, and achieving the antisepsis and anti-inflammation, and is used for preventing and treating the livestock and poultry intestinal diseases such as multiple kinds of pathogenic escherichia coli (dissociant, drug-resistant strains and multiple serotypes), salmonella, necrotic enteritis and duck serositis, so that the purpose of complete radical treatment is achieved. The preparation process has the advantages of being wide in raw material source, low in price, simple in extraction process, remarkable in curative effect and capable of improving immunity.
Description
Technical field
The invention belongs to pharmaceutical technology sectors, be specifically related to the preparation technology that a kind of Chinese herbal medicine for the treatment of poultry treatment intestinal disease concentrates medicine.
Background technology
In recent years, the intensive chicken farm in the many areas of China, vaccary, the large-scale intestinal tract disease of easy generation, livestock and poultry intestinal canal diseases refers under merchandized handling condition, the intestinal tract disease that the infection caused for the many reasons such as cause of disease and adverse environmental factors with virus, antibacterial, mycoplasma or mixed infection cause, this disease causes huge economic loss to raiser, during application this type of disease of antibiotic therapy, because pathogenic factor its Different therapeutical effect different is very large, and it is single for a long time, apply certain antibiotic, being easy to produce Resistant strain affects its curative effect; And the antibiotic therapeutic modality of this employing, reduce the resistivity that fowl stores, cause this kind of disease to take place frequently outbreak, and the cost compare of medication is high, in addition, long-term antibiotic use can cause fowl to store the decline of meat.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art and provide that a kind of raw material sources are extensive, cheap, extraction process is simple, improve immunity, the Chinese herbal medicine for the treatment of poultry evident in efficacy treatment intestinal disease concentrates the preparation technology of medicine.
Technical solution of the present invention is: a kind of Chinese herbal medicine for the treatment of poultry treatment intestinal disease concentrates the preparation technology of medicine, and described preparation technology comprises:
Step 1: selection: choose the Radix Pulsatillae 60 parts, Rhizoma Coptidis 30 parts, Cortex Phellodendri 60 parts, Cortex Fraxini 60 parts, flower of poplar 60 parts, Pericarpium Granati 100 parts, horse order Herba Amaranthi tricoloris 100 parts, Radix Isatidis 100 parts and Radix Scutellariae 800 parts according to quality proportioning and be placed in container;
Step 2: soak: the mixture getting the water soaking Radix Pulsatillae of 10 times of weight of step 1 Chinese crude drug gross mass, Rhizoma Coptidis, Cortex Phellodendri, Cortex Fraxini, flower of poplar, Pericarpium Granati, horse order Herba Amaranthi tricoloris, Radix Isatidis and Radix Scutellariae, soak time is 15-20min;
Step 3: first time lixiviate: by the mixture boiled after adding water in step 2, then the 25-35min that simmers in water;
Step 4: first time filters: by the mixture obtained in step 3 by releasing in drainage screen, and collect first time filtrate, obtain first time filtering residue;
Step 5: second time lixiviate: the first time filtering residue after step 4 being filtered boils after adding the water of 5-8 times of weight of step 1 Chinese crude drug gross mass, then the 20-30min that simmers in water;
Step 6: second time is filtered: by the mixture obtained in step 5 by releasing in drainage screen, and collect second time filtrate, obtain second time filtering residue;
Step 7: third time lixiviate: the second time filtering residue after step 6 being filtered boils after adding the water of 3-5 times of weight of step 1 Chinese crude drug gross mass, then the 10-20min that simmers in water;
Step 8: third time filters: by the mixture obtained in step 7 by releasing in drainage screen, and collect third time filtrate;
Step 9: merge: flow through macroporous adsorptive resins after first time filtrate step 4, step 6 and step 8 obtained, second time filtrate and third time filtrate merging, obtain amalgamation liquid;
Step 10: concentrated: by the amalgamation liquid concentrating under reduced pressure obtained in step 9, control temperature is 60 DEG C, the ratio choosing medical material gross mass (Kg) in the volume (L) of the concentrated solution after concentrated and step 1 is 5:7;
Step 11: storage: concentrated solution step 10 obtained collects storage at normal temperatures and pressures;
The filtration rank of described drainage screen is 35 orders.
The present invention has the following advantages: the present invention is based on Traditional Chinese medical theory, with reference to modern pharmacological research achievement, pure Chinese medicine matching principle is utilized to make, there is heat-clearing and toxic substances removing, dampness-eliminating and dysentery-stopping, blood circulation promoting and blood stasis dispelling, effect of anti-inflammation, multiple Escherichia coli (the dissociant of class is stored for preventing and treating fowl, Resistant strain, various serotype), Salmonella, necrotic enteritis, the intestinal diseases such as duck oromeningitis, reach the object of thoroughly radical cure, it is extensive that the present invention has raw material sources, cheap, extraction process is simple, improve immunity, advantage evident in efficacy.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1
The Chinese herbal medicine for the treatment of poultry treatment intestinal disease concentrates a preparation technology for medicine, and described preparation technology comprises:
Step 1: selection: choose the Radix Pulsatillae 60 parts, Rhizoma Coptidis 30 parts, Cortex Phellodendri 60 parts, Cortex Fraxini 60 parts, flower of poplar 60 parts, Pericarpium Granati 100 parts, horse order Herba Amaranthi tricoloris 100 parts, Radix Isatidis 100 parts and Radix Scutellariae 800 parts according to quality proportioning and be placed in container;
Step 2: soak: the mixture getting the water soaking Radix Pulsatillae of 10 times of weight of step 1 Chinese crude drug gross mass, Rhizoma Coptidis, Cortex Phellodendri, Cortex Fraxini, flower of poplar, Pericarpium Granati, horse order Herba Amaranthi tricoloris, Radix Isatidis and Radix Scutellariae, soak time is 15-20min;
Step 3: first time lixiviate: by the mixture boiled after adding water in step 2, then the 25-35min that simmers in water;
Step 4: first time filters: by the mixture obtained in step 3 by releasing in drainage screen, and collect first time filtrate, obtain first time filtering residue;
Step 5: second time lixiviate: the first time filtering residue after step 4 being filtered boils after adding the water of 5-8 times of weight of step 1 Chinese crude drug gross mass, then the 20-30min that simmers in water;
Step 6: second time is filtered: by the mixture obtained in step 5 by releasing in drainage screen, and collect second time filtrate, obtain second time filtering residue;
Step 7: third time lixiviate: the second time filtering residue after step 6 being filtered boils after adding the water of 3-5 times of weight of step 1 Chinese crude drug gross mass, then the 10-20min that simmers in water;
Step 8: third time filters: by the mixture obtained in step 7 by releasing in drainage screen, and collect third time filtrate;
Step 9: merge: flow through macroporous adsorptive resins after first time filtrate step 4, step 6 and step 8 obtained, second time filtrate and third time filtrate merging, obtain amalgamation liquid;
Step 10: concentrated: by the amalgamation liquid concentrating under reduced pressure obtained in step 9, control temperature is 60 DEG C, the ratio choosing medical material gross mass (Kg) in the volume (L) of the concentrated solution after concentrated and step 1 is 5:7;
Step 11: storage: concentrated solution step 10 obtained collects storage at normal temperatures and pressures;
The present invention has the following advantages: the present invention is based on Traditional Chinese medical theory, with reference to modern pharmacological research achievement, pure Chinese medicine matching principle is utilized to make, there is heat-clearing and toxic substances removing, dampness-eliminating and dysentery-stopping, blood circulation promoting and blood stasis dispelling, effect of anti-inflammation, multiple Escherichia coli (the dissociant of class is stored for preventing and treating fowl, Resistant strain, various serotype), Salmonella, necrotic enteritis, the intestinal diseases such as duck oromeningitis, reach the object of thoroughly radical cure, it is extensive that the present invention has raw material sources, cheap, extraction process is simple, improve immunity, advantage evident in efficacy.
Embodiment 2
The Chinese herbal medicine for the treatment of poultry treatment intestinal disease concentrates a preparation technology for medicine, and described preparation technology comprises:
Step 1: selection: choose the Radix Pulsatillae 60 parts, Rhizoma Coptidis 30 parts, Cortex Phellodendri 60 parts, Cortex Fraxini 60 parts, flower of poplar 60 parts, Pericarpium Granati 100 parts, horse order Herba Amaranthi tricoloris 100 parts, Radix Isatidis 100 parts and Radix Scutellariae 800 parts according to quality proportioning and be placed in container;
Step 2: soak: the mixture getting the water soaking Radix Pulsatillae of 10 times of weight of step 1 Chinese crude drug gross mass, Rhizoma Coptidis, Cortex Phellodendri, Cortex Fraxini, flower of poplar, Pericarpium Granati, horse order Herba Amaranthi tricoloris, Radix Isatidis and Radix Scutellariae, soak time is 15-20min;
Step 3: first time lixiviate: by the mixture boiled after adding water in step 2, then the 25-35min that simmers in water;
Step 4: first time filters: by the mixture obtained in step 3 by releasing in drainage screen, and collect first time filtrate, obtain first time filtering residue;
Step 5: second time lixiviate: the first time filtering residue after step 4 being filtered boils after adding the water of 5-8 times of weight of step 1 Chinese crude drug gross mass, then the 20-30min that simmers in water;
Step 6: second time is filtered: by the mixture obtained in step 5 by releasing in drainage screen, and collect second time filtrate, obtain second time filtering residue;
Step 7: third time lixiviate: the second time filtering residue after step 6 being filtered boils after adding the water of 3-5 times of weight of step 1 Chinese crude drug gross mass, then the 10-20min that simmers in water;
Step 8: third time filters: by the mixture obtained in step 7 by releasing in drainage screen, and collect third time filtrate;
Step 9: merge: flow through macroporous adsorptive resins after first time filtrate step 4, step 6 and step 8 obtained, second time filtrate and third time filtrate merging, obtain amalgamation liquid;
Step 10: concentrated: by the amalgamation liquid concentrating under reduced pressure obtained in step 9, control temperature is 60 DEG C, the ratio choosing medical material gross mass (Kg) in the volume (L) of the concentrated solution after concentrated and step 1 is 5:7;
Step 11: storage: concentrated solution step 10 obtained collects storage at normal temperatures and pressures;
The filtration rank of described drainage screen is 35 orders.
The present invention has the following advantages: the present invention is based on Traditional Chinese medical theory, with reference to modern pharmacological research achievement, pure Chinese medicine matching principle is utilized to make, there is heat-clearing and toxic substances removing, dampness-eliminating and dysentery-stopping, blood circulation promoting and blood stasis dispelling, effect of anti-inflammation, multiple Escherichia coli (the dissociant of class is stored for preventing and treating fowl, Resistant strain, various serotype), Salmonella, necrotic enteritis, the intestinal diseases such as duck oromeningitis, reach the object of thoroughly radical cure, it is extensive that the present invention has raw material sources, cheap, extraction process is simple, improve immunity, advantage evident in efficacy.
Claims (2)
1. the Chinese herbal medicine for the treatment of poultry treatment intestinal disease concentrates a preparation technology for medicine, it is characterized in that: described preparation technology comprises:
Step 1: selection: choose the Radix Pulsatillae 60 parts, Rhizoma Coptidis 30 parts, Cortex Phellodendri 60 parts, Cortex Fraxini 60 parts, flower of poplar 60 parts, Pericarpium Granati 100 parts, horse order Herba Amaranthi tricoloris 100 parts, Radix Isatidis 100 parts and Radix Scutellariae 800 parts according to quality proportioning and be placed in container;
Step 2: soak: the mixture getting the water soaking Radix Pulsatillae of 10 times of weight of step 1 Chinese crude drug gross mass, Rhizoma Coptidis, Cortex Phellodendri, Cortex Fraxini, flower of poplar, Pericarpium Granati, horse order Herba Amaranthi tricoloris, Radix Isatidis and Radix Scutellariae, soak time is 15-20min;
Step 3: first time lixiviate: by the mixture boiled after adding water in step 2, then the 25-35min that simmers in water;
Step 4: first time filters: by the mixture obtained in step 3 by releasing in drainage screen, and collect first time filtrate, obtain first time filtering residue;
Step 5: second time lixiviate: the first time filtering residue after step 4 being filtered boils after adding the water of 5-8 times of weight of step 1 Chinese crude drug gross mass, then the 20-30min that simmers in water;
Step 6: second time is filtered: by the mixture obtained in step 5 by releasing in drainage screen, and collect second time filtrate, obtain second time filtering residue;
Step 7: third time lixiviate: the second time filtering residue after step 6 being filtered boils after adding the water of 3-5 times of weight of step 1 Chinese crude drug gross mass, then the 10-20min that simmers in water;
Step 8: third time filters: by the mixture obtained in step 7 by releasing in drainage screen, and collect third time filtrate;
Step 9: merge: flow through macroporous adsorptive resins after first time filtrate step 4, step 6 and step 8 obtained, second time filtrate and third time filtrate merging, obtain amalgamation liquid;
Step 10: concentrated: by the amalgamation liquid concentrating under reduced pressure obtained in step 9, control temperature is 60 DEG C, the ratio choosing medical material gross mass (Kg) in the volume (L) of the concentrated solution after concentrated and step 1 is 5:7
Step 11: storage: concentrated solution step 10 obtained collects storage at normal temperatures and pressures.
2. a kind of Chinese herbal medicine for the treatment of poultry treatment intestinal disease described in concentrates the preparation technology of medicine, it is characterized in that: the filtration rank of described drainage screen is 35 orders.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111658704A (en) * | 2020-07-14 | 2020-09-15 | 河南康普润生物科技有限公司 | Traditional Chinese medicine composition for preventing and treating intestinal diseases of livestock and poultry and application thereof |
Citations (4)
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| CN101574429A (en) * | 2009-06-16 | 2009-11-11 | 王有成 | Chinese medicinal herb for treating enteritis of beasts and fowls |
| CN103316100A (en) * | 2013-07-12 | 2013-09-25 | 镇江天和生物技术有限公司 | Chinese-western compound preparation for treating chicken colibaciuosis |
| CN103463275A (en) * | 2013-09-28 | 2013-12-25 | 青岛殖富园机械有限公司 | Nanometer Chinese materia medica preparation used for treating dysentery of beasts and birds and manufacturing method of nanometer Chinese materia medica preparation |
| CN104208294A (en) * | 2013-09-29 | 2014-12-17 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for treating piglet yellow-white dysentery and preparation method thereof |
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- 2015-08-25 CN CN201510522324.6A patent/CN105055614A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101574429A (en) * | 2009-06-16 | 2009-11-11 | 王有成 | Chinese medicinal herb for treating enteritis of beasts and fowls |
| CN103316100A (en) * | 2013-07-12 | 2013-09-25 | 镇江天和生物技术有限公司 | Chinese-western compound preparation for treating chicken colibaciuosis |
| CN103463275A (en) * | 2013-09-28 | 2013-12-25 | 青岛殖富园机械有限公司 | Nanometer Chinese materia medica preparation used for treating dysentery of beasts and birds and manufacturing method of nanometer Chinese materia medica preparation |
| CN104208294A (en) * | 2013-09-29 | 2014-12-17 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for treating piglet yellow-white dysentery and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111658704A (en) * | 2020-07-14 | 2020-09-15 | 河南康普润生物科技有限公司 | Traditional Chinese medicine composition for preventing and treating intestinal diseases of livestock and poultry and application thereof |
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Application publication date: 20151118 |