CN102038813A - Coconut palm leaf extract and preparation method and use thereof - Google Patents
Coconut palm leaf extract and preparation method and use thereof Download PDFInfo
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- CN102038813A CN102038813A CN2009102086468A CN200910208646A CN102038813A CN 102038813 A CN102038813 A CN 102038813A CN 2009102086468 A CN2009102086468 A CN 2009102086468A CN 200910208646 A CN200910208646 A CN 200910208646A CN 102038813 A CN102038813 A CN 102038813A
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- leaf extract
- cocos nucifera
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Abstract
The invention discloses a coconut palm leaf extract and a preparation method and use thereof. The invention is characterized in that the extract contains total phenolic components and can be used for preparing food additive, cough syrup and medicaments for clearing heat, diminishing inflammation, treating tinea corporis, diabetes, hyperlipaemia, flue and tumor, losing weight and the like.
Description
Technical field
The present invention relates to a kind of is the Chinese medicine extract that contains the various active composition, preparation method of feedstock production and the new purposes aspect medical thereof with the Cortex cocois radicis leaves, belongs to technical field of Chinese medicines.
Background technology
Cortex cocois radicis is the fruit of babassu Cocos nucifera L., the equal edible of pulp and juice, and materials for improving vision is sobered up and is good for the stomach, and the root of leaf tree is to boil water can treat inflammation.
The Cocos nucifera L. leaf does not have a clear and definite record as medicinal, and the Cortex cocois radicis leaves that especially do not appear in the newspapers is used for cough-relieving, antiseptic, heat clearing away sterilization, treatment influenza, treatment hyperlipidemia, fat-reducing, treatment diabetes, the application in the medicines such as treatment tumor.
Summary of the invention
The preparation method, and the new purposes of Cocos nucifera L. leaf extract aspect medical that the purpose of this invention is to provide a kind of extract, Cocos nucifera L. leaf extract of Cortex cocois radicis leaves.
Cocos nucifera L. leaf extract provided by the invention is characterized in that this extract contains the total phenols composition, and available following method obtains:
A kind of Cocos nucifera L. leaf extract is characterized in that: this extract contains the total phenol property composition, and available following method obtains:
(1) earlier 5～8 times of water of medical material weight or alcoholic solvent are heated or room temperature is extracted at 30 ℃～100 ℃, obtain extracting solution;
(2) extracting solution is cooled to below 30 ℃, removes the wax fat on extracting solution top layer with considering net;
(3) with extracting solution in temperature behind 30 ℃～100 ℃ normal pressures or concentrating under reduced pressure, with medical material weight 1～8 times of water dissolution, centrifugal or static filtration discards precipitation, gets supernatant;
(4) supernatant is passed through exchange column, first water eluting, the eluent waste liquid, reuse concentration is greater than 70% ethanol elution, and at 30 ℃～90 ℃ following concentrating under reduced pressure, drying under reduced pressure or lyophilization obtain the Cocos nucifera L. leaf extract with eluent.
The invention provides a kind of preparation method of Cocos nucifera L. leaf extract, this method may further comprise the steps:
(1) get green fresh and alive Cortex cocois radicis leaves, clean, chopping is heated or room temperature is carried out the extraction first time at 30 ℃～100 ℃ with the water of 5～8 times of medical material weight or alcoholic solvent, obtains extracting solution;
(2), remove the wax fat on extracting solution top layer with considering net with the extracting solution natural cooling;
(3) with the extracting solution behind the wax removing fat through considering net filtration;
(4) heat or room temperature is carried out the second time and extracted at 30 ℃～100 ℃ with 5～8 times of water or alcoholic solvent with medical material weight, extracting solution is through strainer filtering;
(5) extract for the third time in 30 ℃～100 ℃ heating or room temperature with 5～8 times of water of medical material weight or alcoholic solvent, extracting solution is through strainer filtering;
(6) merge three times and extract the gained extracting solution;
(7) with extracting solution in temperature behind 30 ℃～100 ℃ normal pressures or concentrating under reduced pressure, with medical material weight 1～10 times of water dissolution, centrifugal or static filtration discards precipitation, gets supernatant;
(8) supernatant is passed through exchange column, first water eluting, the eluent waste liquid, reuse concentration is greater than 70% ethanol elution, and at 30 ℃～90 ℃ following concentrating under reduced pressure, drying under reduced pressure or lyophilization obtain the Cocos nucifera L. leaf extract with eluent.
Exchange column of the present invention adopts macroporous adsorbent resin, ion exchange resin or polyamide.
Technical scheme of the present invention also provides the multiple new purposes of Cocos nucifera L. leaf extract aspect medical:
The application of Cocos nucifera L. leaf extract in preparation treatment cough syrup.
The Cocos nucifera L. leaf extract is as the application of food preservative.
The application of Cocos nucifera L. leaf extract in preparation heat clearing and inflammation relieving medicine.
The application of Cocos nucifera L. leaf extract in preparation treatment tinea corporis medicine.
The application of Cocos nucifera L. leaf extract in preparation treatment influenza medicine.
The application of Cocos nucifera L. leaf extract in preparation treatment hyperlipidemia medicine.
The Cocos nucifera L. leaf extract is in the application of preparation slimming medicine.
The application of Cocos nucifera L. leaf extract in the preparation diabetes medicament.
The application of Cocos nucifera L. leaf extract in preparation medicine for treating tumor thing.
The specific embodiment
The preparation technology of Cocos nucifera L. leaf extract provided by the invention is as follows:
At first get green fresh and alive Cortex cocois radicis leaves, defoliation stalk is cleaned, and chopping is heated or room temperature is carried out the extraction first time at 30 ℃～100 ℃ with the water of 5～8 times of medical material weight or alcoholic solvent, obtains extracting solution; With the extracting solution natural cooling, remove the wax fat on extracting solution top layer then with considering net.Again with the extracting solution behind the wax removing fat through considering net filtration; Reuse medical material weight heats or room temperature is carried out the second time and extracted at 30 ℃～100 ℃ with 5～8 times of water or alcoholic solvent, and extracting solution is through strainer filtering; 5～8 times of water of reuse medical material weight or alcoholic solvent extract for the third time in 30 ℃～100 ℃ heating or room temperature, and extracting solution is through strainer filtering; Merge three times and extract the gained extracting solution; Then with extracting solution in temperature behind 30 ℃～100 ℃ normal pressures or concentrating under reduced pressure, with medical material weight 1～10 times of water dissolution, centrifugal or static filtration discards precipitation, gets supernatant; At last supernatant is passed through exchange column, first water eluting, the eluent waste liquid, reuse concentration is greater than 70% ethanol elution, and at 30 ℃～90 ℃ following concentrating under reduced pressure, drying under reduced pressure or lyophilization obtain the Cocos nucifera L. leaf extract with eluent.
Extract mixes food as food additive exactly as aseptic applications, also can be made into anticorrosion solvent and uses; Using as medicament, is exactly the Cocos nucifera L. leaf extract separately or add in the compound recipe, is prepared into medicament with the preparation process of routine: as powder, and pill, capsule, tablet, membrane, injection, unguentum, tincture, electuary, aerosol, various external preparation etc.
Experimental result of the present invention shows that the Cocos nucifera L. leaf extract has obvious effect to cough-relieving.Soaked with liquid food with containing extract never degenerates for a long time, and it is good anticorrosion in effect to show that the Cocos nucifera L. leaf extract has.Take the liquid that contains the Cocos nucifera L. leaf extract, clearing heat and anti-inflammatory functions is obvious.Be coated with the liquid that contains the Cocos nucifera L. leaf extract and put tinea cruris, tinea pedis on the skin, have obvious therapeutic effect.Experiment shows that the Cocos nucifera L. leaf extract has obvious killing action to cold virus.Cocos nucifera L. leaf extract effect aspect the reduction hyperlipidemia is obvious.The Cocos nucifera L. leaf extract is being removed body fat, reaches fat-reducing purpose aspect, and effect is remarkable.The Cocos nucifera L. leaf extract is at blood sugar lowering content, and the thirsty symptom effect of diabetes-alleviating is remarkable.And the Cocos nucifera L. leaf extract has inhibition and killing action to tumor.
It is emphasized that the foregoing description is illustrative, should not regard limitation of the present invention as.
Claims (11)
1. Cocos nucifera L. leaf extract, it is characterized in that: this extract contains the total phenol property composition, and available following method obtains:
(1) earlier 5～8 times of water of medical material weight or alcoholic solvent are heated or room temperature is extracted at 30 ℃～100 ℃, obtain extracting solution;
(2), remove the wax fat on extracting solution top layer with considering net with the extracting solution natural cooling;
(3) with extracting solution in temperature behind 30 ℃～100 ℃ normal pressures or concentrating under reduced pressure, with medical material weight 1～8 times of water dissolution, centrifugal or static filtration discards precipitation, gets supernatant;
(4) supernatant is passed through exchange column, first water eluting, the eluent waste liquid, reuse concentration is greater than 70% ethanol elution, and at 30 ℃～90 ℃ following concentrating under reduced pressure, drying under reduced pressure or lyophilization obtain the Cocos nucifera L. leaf extract with eluent.
2. the preparation method of Cocos nucifera L. leaf extract according to claim 1, this method comprises the steps:
(1) get green fresh and alive Cortex cocois radicis leaves, clean, chopping is heated or room temperature is carried out the extraction first time at 30 ℃～100 ℃ with the water of 5～8 times of medical material weight or alcoholic solvent, obtains extracting solution;
(2) extracting solution is cooled to below 30 ℃, knows the wax fat on extracting solution top layer with the worry net.
(3) with the extracting solution behind the wax removing fat through considering net filtration;
(4) heat or room temperature is carried out the second time and extracted at 30 ℃～100 ℃ with 5～8 times of water or alcoholic solvent with medical material weight, extracting solution is through strainer filtering;
(5) extract for the third time in 30 ℃～100 ℃ heating or room temperature with 5～8 times of water of medical material weight or alcoholic solvent, extracting solution is through strainer filtering;
(6) merge three times and extract the gained extracting solution.
(7) with extracting solution in temperature behind 30 ℃～100 ℃ normal pressures or concentrating under reduced pressure, with medical material weight 1～10 times of water dissolution, centrifugal or static filtration discards precipitation, gets supernatant;
(8) supernatant is passed through exchange column, first water eluting, the eluent waste liquid, reuse concentration is greater than 70% ethanol elution, and at 30 ℃～90 ℃ following concentrating under reduced pressure, drying under reduced pressure or lyophilization obtain the Cocos nucifera L. leaf extract with eluent.
3. the application of Cocos nucifera L. leaf extract as claimed in claim 1 in preparation treatment cough syrup.
4. Cocos nucifera L. leaf extract as claimed in claim 1 is as the application of food preservative.
5. the application of Cocos nucifera L. leaf extract as claimed in claim 1 in preparation heat clearing and inflammation relieving medicine.
6. the application of Cocos nucifera L. leaf extract as claimed in claim 1 in preparation treatment tinea corporis medicine.
7. the application of Cocos nucifera L. leaf extract as claimed in claim 1 in preparation treatment influenza medicine.
8. the application of Cocos nucifera L. leaf extract as claimed in claim 1 in preparation treatment hyperlipidemia medicine.
9. Cocos nucifera L. leaf extract as claimed in claim 1 is in the application of preparation slimming medicine.
10. the application of Cocos nucifera L. leaf extract as claimed in claim 1 in the preparation diabetes medicament.
11. the application of Cocos nucifera L. leaf extract in preparation medicine for treating tumor thing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102086468A CN102038813A (en) | 2009-10-23 | 2009-10-23 | Coconut palm leaf extract and preparation method and use thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009102086468A CN102038813A (en) | 2009-10-23 | 2009-10-23 | Coconut palm leaf extract and preparation method and use thereof |
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| CN102038813A true CN102038813A (en) | 2011-05-04 |
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| CN2009102086468A Pending CN102038813A (en) | 2009-10-23 | 2009-10-23 | Coconut palm leaf extract and preparation method and use thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102511472A (en) * | 2011-12-30 | 2012-06-27 | 北京市第一○一中学 | Spathiphyllum leaf extract and its preparation method and application |
| CN102972456A (en) * | 2012-12-25 | 2013-03-20 | 中国热带农业科学院椰子研究所 | Coconut tree stem essential oil extract and application thereof in Oryctes rhinoceros(Linnaeus) attractant |
| WO2013179308A2 (en) * | 2012-06-01 | 2013-12-05 | Benny Antony | A composition with anti hyperglycemic and antioxidant activity obtained from the extract of parts of coconut and a method of producing the same |
-
2009
- 2009-10-23 CN CN2009102086468A patent/CN102038813A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102511472A (en) * | 2011-12-30 | 2012-06-27 | 北京市第一○一中学 | Spathiphyllum leaf extract and its preparation method and application |
| CN102511472B (en) * | 2011-12-30 | 2013-12-11 | 北京市第一○一中学 | Spathiphyllum leaf extract and its preparation method and application |
| WO2013179308A2 (en) * | 2012-06-01 | 2013-12-05 | Benny Antony | A composition with anti hyperglycemic and antioxidant activity obtained from the extract of parts of coconut and a method of producing the same |
| WO2013179308A3 (en) * | 2012-06-01 | 2014-01-16 | Benny Antony | A composition with anti hyperglycemic and antioxidant activity obtained from the extract of parts of coconut and a method of producing the same |
| CN102972456A (en) * | 2012-12-25 | 2013-03-20 | 中国热带农业科学院椰子研究所 | Coconut tree stem essential oil extract and application thereof in Oryctes rhinoceros(Linnaeus) attractant |
| CN102972456B (en) * | 2012-12-25 | 2014-08-27 | 中国热带农业科学院椰子研究所 | Coconut tree stem essential oil extract and application thereof in Oryctes rhinoceros(Linnaeus) attractant |
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Application publication date: 20110504 |