WO2013179308A3 - A composition with anti hyperglycemic and antioxidant activity obtained from the extract of parts of coconut and a method of producing the same - Google Patents

A composition with anti hyperglycemic and antioxidant activity obtained from the extract of parts of coconut and a method of producing the same Download PDF

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Publication number
WO2013179308A3
WO2013179308A3 PCT/IN2013/000342 IN2013000342W WO2013179308A3 WO 2013179308 A3 WO2013179308 A3 WO 2013179308A3 IN 2013000342 W IN2013000342 W IN 2013000342W WO 2013179308 A3 WO2013179308 A3 WO 2013179308A3
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WO
WIPO (PCT)
Prior art keywords
range
composition
producing
extract
coconut
Prior art date
Application number
PCT/IN2013/000342
Other languages
French (fr)
Other versions
WO2013179308A2 (en
Inventor
Benny Antony
Original Assignee
Benny Antony
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Benny Antony filed Critical Benny Antony
Publication of WO2013179308A2 publication Critical patent/WO2013179308A2/en
Publication of WO2013179308A3 publication Critical patent/WO2013179308A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a composition with anti-hyperglycemic, antidiabetic and antioxidant activity obtained from the extract of parts of coconut tree selected from roots, bark, trunk, leaves and coconut shell and husk or combinations thereof and a method of producing the same. The composition is polyphenols in the range of 5-80%, flavonoids in the range of 0.2-10%, tannins in the range of 10-60%, saponins in the range of 1-30%, alkaloids in the range of 1-25%, anthocyanins in the range of 0.1-5%, proteins in the range of 1-10% and carbohydrate in the range of 1-30%. A method of producing said composition mainly comprising of extracting with solvents selected from water, hexane, methanol, ethanol, isopropanol, n-butanol, methyl acetate, ethyl acetate, propyl acetate, n-butyl acetate and combinations thereof to obtain the said extract followed by concentrating and drying to obtain in dry powder form. It is administered to patients in the form of oral dosage and in the form of infusion, injection and ampoule.
PCT/IN2013/000342 2012-06-01 2013-05-29 A composition with anti hyperglycemic and antioxidant activity obtained from the extract of parts of coconut and a method of producing the same WO2013179308A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2216/CHE/2012 2012-06-01
IN2216CH2012 2012-06-01

Publications (2)

Publication Number Publication Date
WO2013179308A2 WO2013179308A2 (en) 2013-12-05
WO2013179308A3 true WO2013179308A3 (en) 2014-01-16

Family

ID=49673996

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2013/000342 WO2013179308A2 (en) 2012-06-01 2013-05-29 A composition with anti hyperglycemic and antioxidant activity obtained from the extract of parts of coconut and a method of producing the same

Country Status (1)

Country Link
WO (1) WO2013179308A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006083146A (en) * 2004-09-15 2006-03-30 Shonan Institute For Medical & Preventive Science Blood glucose level increase inhibitor
CN102038813A (en) * 2009-10-23 2011-05-04 郭强 Coconut palm leaf extract and preparation method and use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006083146A (en) * 2004-09-15 2006-03-30 Shonan Institute For Medical & Preventive Science Blood glucose level increase inhibitor
CN102038813A (en) * 2009-10-23 2011-05-04 郭强 Coconut palm leaf extract and preparation method and use thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ISHA, DEBMANDAL ET AL.: "Coconut (Cocos nucifera L.: Arecaceae): In health promotion and disease prevention.", ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE., 20 March 2011 (2011-03-20), pages 41 - 274 *
TAN, PINXIN ET AL.: "Research Advances in Antioxidant Composition of Botanical Extracts and Their Action Mechanisms.", FOOD SCIENCE., vol. 31, no. 15, 2010, pages 288 - 292 *
ZHOU RONGHAN ET AL., PLANT CHEMOTAXONOMY., October 2005 (2005-10-01), pages 1231 - 1232 *

Also Published As

Publication number Publication date
WO2013179308A2 (en) 2013-12-05

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