CN105560425A - Preparation method of collateral-dredging oral liquid - Google Patents

Preparation method of collateral-dredging oral liquid Download PDF

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Publication number
CN105560425A
CN105560425A CN201510876456.9A CN201510876456A CN105560425A CN 105560425 A CN105560425 A CN 105560425A CN 201510876456 A CN201510876456 A CN 201510876456A CN 105560425 A CN105560425 A CN 105560425A
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China
Prior art keywords
radix
filtrate
oral liquid
angelicae sinensis
flos carthami
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Pending
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CN201510876456.9A
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Chinese (zh)
Inventor
王耀斌
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Shaanxi Shengmai Petroleum Co Ltd
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Shaanxi Shengmai Petroleum Co Ltd
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Priority to CN201510876456.9A priority Critical patent/CN105560425A/en
Publication of CN105560425A publication Critical patent/CN105560425A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254—Acanthopanax or Eleutherococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716—Clematis (leather flower)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a traditional Chinese medicine oral liquid, in particular to a preparation method of a collateral-dredging oral liquid, comprising the following steps: (1), taking 150 g of Radix Angelicae Sinensis, 100 g of Ramulus Cinnamomi, 65 g of Flos Carthami, 150 g of Cortex Acanthopanacis, 150 g of Cortex Eucommiae, 150 g of Radix Clematidis, 150 g of Radix Gentianae Macrophyllae, 150 g of Radix Achyranthis Bidentatae, 200 g of Radix Salviae Miltiorrhizae and 150 g of Radix Astragali for use. The preparation method of the collateral-dredging oral liquid has a simple process and is suitable for industrial production and highly practical.

Description

A kind of preparation method of ruton oral liquid
Technical field
The present invention relates to a kind of Chinese medicine oral liquid, particularly a kind of preparation method of ruton oral liquid.
Background technology
Ruton oral liquid is the cipher prescription of Affiliated Hospital of Yongzhou Vocational Technical College department of Chinese medicine, applies to clinical more than ten years, evident in efficacy.This preparation drives wind prevailing over dampness, promoting the flow of QI in the collateral by warming the meridian, blood circulation promoting and blood stasis dispelling, bone and muscle strengthening, for rheumatic arthritis, and cervical vertebra, lumbar vertebra hyperosteogeny, sciatica, the diseases such as numb limbs and tense tendons.
Summary of the invention
The present invention proposes a kind of preparation method of ruton oral liquid.
The preparation method of ruton oral liquid of the present invention, comprises the following steps: (1) gets Radix Angelicae Sinensis 150g, Ramulus Cinnamomi 100g, Flos Carthami 65g, Cortex Acanthopancis 150g, Cortex Eucommiae 150g, Radix Clematidis 150g, and Qin Wan 150g, cattle sunset 150g, Radix Salviae Miltiorrhizae 200g, Radix Astragali 150g are for subsequent use; (2) above l0 taste medicine is shone the percolation under extractum and extractum item, Radix Angelicae Sinensis, Ramulus Cinnamomi, the Cortex Eucommiae, Flos Carthami are respectively with crude drug in whole number 7 times, 70% ethanol proofing 48h of Cortex Eucommiae crude drug in whole number 6 times carries out percolation respectively, wherein Radix Angelicae Sinensis, Flos Carthami collects just filtrate 180 and 90mL respectively, another device is preserved, and continues percolation and collects full filtrate; (3) get Cortex Acanthopancis, Radix Clematidis, Qin Wan, Niu Xi, Radix Salviae Miltiorrhizae, the Radix Astragali and above-mentioned medicinal residues decoct 2 times, and each 2h collecting decoction filters, filtrate is concentrated into relative density and is about 1.2, adds ethanol and makes alcohol content be 50%, stir evenly, leave standstill and filter, filtrate and subsequent filtrate merge, and reclaim ethanol and are concentrated in right amount; (4) add above-mentioned Radix Angelicae Sinensis, Flos Carthami is filtrate and careless syrup 294mL just; Just become 1000mL with acetic acid allotment again, pull even, leave standstill filtration, namely obtain ruton oral liquid.
The preparation method of ruton oral liquid of the present invention, technical process is simple, can industry words produce, practical.
Detailed description of the invention:
The preparation method of ruton oral liquid of the present invention, comprises the following steps: (1) gets Radix Angelicae Sinensis 150g, Ramulus Cinnamomi 100g, Flos Carthami 65g, Cortex Acanthopancis 150g, Cortex Eucommiae 150g, Radix Clematidis 150g, and Qin Wan 150g, cattle sunset 150g, Radix Salviae Miltiorrhizae 200g, Radix Astragali 150g are for subsequent use; (2) above lO taste medicine is shone the percolation under extractum and extractum item, Radix Angelicae Sinensis, Ramulus Cinnamomi, the Cortex Eucommiae, Flos Carthami are respectively with crude drug in whole number 7 times, 70% ethanol proofing 48h of Cortex Eucommiae crude drug in whole number 6 times carries out percolation respectively, wherein Radix Angelicae Sinensis, Flos Carthami collects just filtrate 180 and 90mL respectively, another device is preserved, and continues percolation and collects full filtrate; (3) get Cortex Acanthopancis, Radix Clematidis, Qin Wan, Niu Xi, Radix Salviae Miltiorrhizae, the Radix Astragali and above-mentioned medicinal residues decoct 2 times, and each 2h collecting decoction filters, filtrate is concentrated into relative density and is about 1.2, adds ethanol and makes alcohol content be 50%, stir evenly, leave standstill and filter, filtrate and subsequent filtrate merge, and reclaim ethanol and are concentrated in right amount; (4) add above-mentioned Radix Angelicae Sinensis, Flos Carthami is filtrate and careless syrup 294mL just; Just become 1000mL with acetic acid allotment again, pull even, leave standstill filtration, namely obtain ruton oral liquid.
The preparation method of ruton oral liquid of the present invention, technical process is simple, can industry words produce, practical.

Claims (1)

1. the preparation method of ruton oral liquid, comprises the following steps: (1) gets Radix Angelicae Sinensis 150g, Ramulus Cinnamomi 100g, Flos Carthami 65g, Cortex Acanthopancis 150g, Cortex Eucommiae 150g, Radix Clematidis 150g, and Qin Wan 150g, cattle sunset 150g, Radix Salviae Miltiorrhizae 200g, Radix Astragali 150g are for subsequent use; (2) above lO taste medicine is shone the percolation under extractum and extractum item, Radix Angelicae Sinensis, Ramulus Cinnamomi, the Cortex Eucommiae, Flos Carthami are respectively with crude drug in whole number 7 times, 70% ethanol proofing 48h of Cortex Eucommiae crude drug in whole number 6 times carries out percolation respectively, wherein Radix Angelicae Sinensis, Flos Carthami collects just filtrate 180 and 90mL respectively, another device is preserved, and continues percolation and collects full filtrate; (3) get Cortex Acanthopancis, Radix Clematidis, Qin Wan, Niu Xi, Radix Salviae Miltiorrhizae, the Radix Astragali and above-mentioned medicinal residues decoct 2 times, and each 2h collecting decoction filters, filtrate is concentrated into relative density and is about 1.2, adds ethanol and makes alcohol content be 50%, stir evenly, leave standstill and filter, filtrate and subsequent filtrate merge, and reclaim ethanol and are concentrated in right amount; (4) add above-mentioned Radix Angelicae Sinensis, Flos Carthami is filtrate and careless syrup 294mL just; Just become 1000mL with acetic acid allotment again, pull even, leave standstill filtration, namely obtain ruton oral liquid.
CN201510876456.9A 2015-12-03 2015-12-03 Preparation method of collateral-dredging oral liquid Pending CN105560425A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
CN201510876456.9A CN105560425A (en) 2015-12-03 2015-12-03 Preparation method of collateral-dredging oral liquid

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CN105560425A true CN105560425A (en) 2016-05-11

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266769A (en) * 2016-09-06 2017-01-04 陈秀成 Dragon returns ginseng oral liquid and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266769A (en) * 2016-09-06 2017-01-04 陈秀成 Dragon returns ginseng oral liquid and preparation method thereof

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