CN105051546A - 蜂窝管 - Google Patents

蜂窝管 Download PDF

Info

Publication number
CN105051546A
CN105051546A CN201380062086.4A CN201380062086A CN105051546A CN 105051546 A CN105051546 A CN 105051546A CN 201380062086 A CN201380062086 A CN 201380062086A CN 105051546 A CN105051546 A CN 105051546A
Authority
CN
China
Prior art keywords
well
fluid
chamber
amplification
planar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380062086.4A
Other languages
English (en)
Chinese (zh)
Inventor
蒋裕民
道格·多利特
杜斯丁·狄更斯
詹妮弗·格拉斯
鲁埃尔·万埃塔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cepheid
Original Assignee
Cepheid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cepheid filed Critical Cepheid
Priority to CN202010734994.5A priority Critical patent/CN111979092A/zh
Publication of CN105051546A publication Critical patent/CN105051546A/zh
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0642Filling fluids into wells by specific techniques
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0673Handling of plugs of fluid surrounded by immiscible fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0636Integrated biosensor, microarrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0819Microarrays; Biochips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Rigid containers without fluid transport within
    • B01L3/5085Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50851Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Food Science & Technology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • External Artificial Organs (AREA)
CN201380062086.4A 2012-09-26 2013-09-26 蜂窝管 Pending CN105051546A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010734994.5A CN111979092A (zh) 2012-09-26 2013-09-26 蜂窝管

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261706115P 2012-09-26 2012-09-26
US61/706,115 2012-09-26
US13/843,739 US9914968B2 (en) 2012-09-26 2013-03-15 Honeycomb tube
US13/843,739 2013-03-15
PCT/US2013/062042 WO2014052671A1 (en) 2012-09-26 2013-09-26 Honeycomb tube

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202010734994.5A Division CN111979092A (zh) 2012-09-26 2013-09-26 蜂窝管

Publications (1)

Publication Number Publication Date
CN105051546A true CN105051546A (zh) 2015-11-11

Family

ID=50339439

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201380062086.4A Pending CN105051546A (zh) 2012-09-26 2013-09-26 蜂窝管
CN202010734994.5A Pending CN111979092A (zh) 2012-09-26 2013-09-26 蜂窝管

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202010734994.5A Pending CN111979092A (zh) 2012-09-26 2013-09-26 蜂窝管

Country Status (12)

Country Link
US (10) US9914968B2 (https=)
JP (2) JP6525877B2 (https=)
KR (1) KR102214419B1 (https=)
CN (2) CN105051546A (https=)
AP (1) AP2015008394A0 (https=)
AU (1) AU2013323428B2 (https=)
BR (1) BR112015006566B1 (https=)
CA (1) CA2886484C (https=)
EA (1) EA031989B1 (https=)
MX (1) MX363399B (https=)
WO (1) WO2014052671A1 (https=)
ZA (1) ZA201502463B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12203135B2 (en) 2012-09-26 2025-01-21 Cepheid Honeycomb tube

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6200948B2 (ja) 2012-05-25 2017-09-20 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル マイクロ流体デバイス
SG2012075792A (en) * 2012-10-09 2014-05-29 Jn Medsys Pte Ltd An improved device and method
MX367967B (es) * 2013-03-15 2019-09-11 Cepheid Aparato de tapa de multiples camaras.
WO2015069743A1 (en) * 2013-11-05 2015-05-14 Biofire Diagnostics, Llc Induction pcr
US11587686B2 (en) 2014-10-16 2023-02-21 Cepheid Biosecurity screening system and method
MX2017012742A (es) * 2015-04-03 2017-11-15 Abbott Lab Dispositivos y metodos para el analisis de muestras.
EP3313573A2 (en) * 2015-07-22 2018-05-02 The University of North Carolina at Chapel Hill Fluidic devices with bead well geometries with spatially separated bead retention and signal detection segments and related methods
US10797567B2 (en) 2015-07-23 2020-10-06 Life Technologies Corporation Rotor assembly including a housing for a sensor array component and methods for using same
EA039230B1 (ru) 2015-07-24 2021-12-21 Сифиид Система для выполнения молекулярных диагностических анализов
JP6808940B2 (ja) * 2016-01-29 2021-01-06 凸版印刷株式会社 アレイデバイス、生体分子解析用キット及び溶媒の封止方法
GB2554377A (en) * 2016-09-23 2018-04-04 Dnanudge Ltd Method and apparatus for analysing a biological sample
KR101997116B1 (ko) * 2016-10-14 2019-07-05 연세대학교 산학협력단 Kras 유전자에 상보적인 가이드 rna 및 이의 용도
US20180208970A1 (en) * 2017-01-23 2018-07-26 America Diagnosis, Inc. Direct quantitative pcr device and method of use thereof
AU2018243360B2 (en) 2017-03-29 2023-10-26 Cornell University Devices, processes, and systems for determination of nucleic acid sequence, expression, copy number, or methylation changes using combined nuclease, ligase, polymerase, and sequencing reactions
US20200102587A1 (en) * 2017-04-05 2020-04-02 Hitachi High-Technologies Corporation Nucleic acid amplification method and nucleic acid analyzer
WO2019131592A1 (ja) * 2017-12-26 2019-07-04 凸版印刷株式会社 標的分子の検出における偽陰性判定の発生を抑制する方法および検出デバイス
PL425106A1 (pl) 2018-03-30 2019-10-07 Bacteromic Spółka Z Ograniczoną Odpowiedzialnością Chip mikroprzepływowy
CN111218383B (zh) * 2018-11-26 2025-09-09 杭州比格飞序生物科技有限公司 一种核酸提取装置及其方法
EP3897981B1 (en) * 2018-12-20 2023-06-07 Imec VZW Addressable micro-reaction chamber array
US11976269B2 (en) * 2019-03-18 2024-05-07 Cellular Research, Inc. Precise delivery of components into fluids
BR112021018728A2 (pt) 2019-03-21 2022-04-05 Sherlock Biosciences Inc Sistema
JP7280101B2 (ja) * 2019-04-23 2023-05-23 株式会社日立製作所 測定セル製造方法、測定セル
EP3966346B1 (en) * 2019-05-08 2023-08-23 DNAe Diagnostics Limited Combined solution phase and solid phase dna amplification
JP7517336B2 (ja) * 2019-05-30 2024-07-17 Toppanホールディングス株式会社 ウェルに液体を導入する方法
US11008627B2 (en) 2019-08-15 2021-05-18 Talis Biomedical Corporation Diagnostic system
US12054320B2 (en) 2019-09-23 2024-08-06 Cepheid Multi-chambered lid apparatus with reagent port
CN114430701B (zh) * 2019-09-23 2024-09-13 塞弗德公司 具有试剂端口的多腔室盖装置
US11730193B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
US11254979B2 (en) 2020-06-01 2022-02-22 Shaheen Innovations Holding Limited Systems and devices for infectious disease screening
CN111190021B (zh) * 2020-02-22 2023-08-11 武汉泰沃科技有限责任公司 一种生物样品处理盒
CA3180786A1 (en) 2020-06-01 2021-05-28 Imad Lahoud An infectious disease screening system
WO2021245391A1 (en) 2020-06-01 2021-12-09 Shaheen Innovations Holding Limited An infectious disease screening device
WO2022071716A1 (en) * 2020-09-29 2022-04-07 Seegene, Inc. Chamber for nucleic acid reaction, method for nucleic acid reaction using the same, and cartridge for sample processing comprising the same
AU2022207990A1 (en) 2021-01-13 2023-08-17 Cepheid Lossy mechatronic systems and methods of estimation
WO2022246723A1 (zh) * 2021-05-27 2022-12-01 京东方科技集团股份有限公司 检测芯片及其制备方法和进样方法
KR20240033032A (ko) * 2021-07-09 2024-03-12 세페이드 높은 수준의 다중화 반응 용기, 시약 점적 장치 및 관련 방법
JP2024531451A (ja) * 2021-08-25 2024-08-29 インテグリス・インコーポレーテッド 剛性フレームバッグ
WO2024263523A1 (en) 2023-06-21 2024-12-26 Cepheid Real-time monitoring of liquid temperature

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6818185B1 (en) * 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
CN1942590A (zh) * 2004-02-18 2007-04-04 周小川 多元化学和生化反应的流体装置和方法
CN101680013A (zh) * 2007-06-11 2010-03-24 和光纯药工业株式会社 微芯片大容量pcr与集成实时ce检测
WO2012049066A2 (en) * 2010-10-12 2012-04-19 Eppendorf Ag Real-time amplification and micro-array based detection of nucleic acid targets in a flow chip assay

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US5168038A (en) 1988-06-17 1992-12-01 The Board Of Trustees Of The Leland Stanford Junior University In situ transcription in cells and tissues
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
JPH03126208A (ja) 1989-10-11 1991-05-29 Nippon Chemicon Corp 電解コンデンサ用電解液
US5427930A (en) 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
SE9002579D0 (sv) * 1990-08-07 1990-08-07 Pharmacia Ab Method and apparatus for carrying out biochemical reactions
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
JP3080178B2 (ja) 1991-02-18 2000-08-21 東洋紡績株式会社 核酸配列の増幅方法およびそのための試薬キット
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US5648211A (en) 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
JP4540754B2 (ja) 1996-06-04 2010-09-08 ユニバーシティ オブ ユタ リサーチ ファウンデーション Pcr中のハイブリダイゼーションのモニタリング
GB9620934D0 (en) * 1996-10-08 1996-11-27 Molecular Drives Limited Multi-well containers
US6403037B1 (en) * 2000-02-04 2002-06-11 Cepheid Reaction vessel and temperature control system
CA2311622A1 (en) * 2000-06-15 2001-12-15 Moussa Hoummady Sub-nanoliter liquid drop dispensing system and method therefor
US8048386B2 (en) 2002-02-25 2011-11-01 Cepheid Fluid processing and control
JP4361271B2 (ja) 2000-10-10 2009-11-11 バイオトローブ・インコーポレイテツド アッセイ、合成、および保存用の器具、ならびに、その作製、使用、および操作の方法
US20080202927A1 (en) * 2000-11-03 2008-08-28 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US8277753B2 (en) 2002-08-23 2012-10-02 Life Technologies Corporation Microfluidic transfer pin
GB0321158D0 (en) * 2003-09-10 2003-10-08 Central Research Lab Ltd Apparatus and method for handling cells,embryos or oocytes
US7414118B1 (en) 2004-04-14 2008-08-19 Applied Biosystems Inc. Modified oligonucleotides and applications thereof
MXPA06014185A (es) 2004-06-07 2007-04-16 Strides Arcolab Ltd Composicion farmaceutica que contiene una solucion estable y clara de medicamento anti-inflmatorio en capsulas de gelatina blanda, y proceso para producirlo.
US7473533B2 (en) 2004-12-30 2009-01-06 Corning Incorporated Membrane arrays and methods of manufacture
GB2423710A (en) 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
EP1717585B1 (en) * 2005-04-28 2013-01-16 FUJIFILM Corporation Microchip and analysis method using the same
WO2007002588A2 (en) * 2005-06-23 2007-01-04 Applera Corporation Thermal-cycling pipette tip
US8043580B2 (en) 2005-10-13 2011-10-25 Nissui Pharmaceutical Co., Ltd. Testing device
BRPI0618273A2 (pt) 2005-11-02 2011-08-23 Teikoku Pharma Usa, Inc. formulações de dosagem oral de ibuprofeno organolepticamente aceitáveis, métodos de produção e uso das mesmas
US8900828B2 (en) 2006-05-01 2014-12-02 Cepheid Methods and apparatus for sequential amplification reactions
US8119352B2 (en) 2006-06-20 2012-02-21 Cepheld Multi-stage amplification reactions by control of sequence replication times
US8187557B2 (en) 2006-07-13 2012-05-29 Cepheid Reagent reservoir system for analytical instruments
JP3126208U (ja) * 2006-08-04 2006-10-19 株式会社島津製作所 示差屈折率検出器及び液体クロマトグラフ。
US20080108122A1 (en) 2006-09-01 2008-05-08 State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon Microchemical nanofactories
WO2008091031A1 (en) * 2007-01-25 2008-07-31 Seoul National University Industry Foundation Method of arraying cells at single-cell level inside microfluidic channel and method of analysing cells using the same, and cell analysis chip used for carrying out the same
CN101896275A (zh) * 2007-12-17 2010-11-24 龚海庆 微流控器件
NL1036865C2 (en) 2009-04-16 2010-10-19 Maxi Miliaan Bv Child vehicle seat.
JP5881936B2 (ja) * 2009-04-20 2016-03-09 ソニー株式会社 試料溶液導入キット及び試料溶液注入器
EP2826564B1 (en) * 2009-11-23 2018-12-26 3M Innovative Properties Company Microwell array articles and methods of use
DE102010041478A1 (de) 2010-09-27 2012-03-29 Zumtobel Lighting Gmbh Anordnung zur gerichteten Lichtabgabe
US8968684B2 (en) * 2011-04-28 2015-03-03 Bin Lian Microplates, reaction modules and detection systems
US9095852B2 (en) * 2011-08-22 2015-08-04 The Regents Of The University Of California Multilayer high density microwells
GB201118774D0 (en) * 2011-10-31 2011-12-14 British American Tobacco Co Fluid distribution in an exposure device
WO2013159116A1 (en) * 2012-04-20 2013-10-24 University Of Chicago Fluidic devices for biospecimen preservation
US9914968B2 (en) 2012-09-26 2018-03-13 Cepheid Honeycomb tube
WO2015116627A1 (en) * 2014-01-29 2015-08-06 Arizona Board Of Regents On Behalf Of Arizona State University Microreactor array platform
WO2015143442A2 (en) * 2014-03-21 2015-09-24 The Trustees Of Columbia University In The City Of New York Methods and devices for selection and isolation of aptamers
CN109863396B (zh) * 2016-10-05 2021-11-05 雅培实验室 用于样品分析的装置和方法
WO2019098301A1 (ja) * 2017-11-17 2019-05-23 凸版印刷株式会社 標的分子の検出方法
WO2020235607A1 (ja) * 2019-05-21 2020-11-26 凸版印刷株式会社 標的分子の検出方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6818185B1 (en) * 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
CN1942590A (zh) * 2004-02-18 2007-04-04 周小川 多元化学和生化反应的流体装置和方法
CN101680013A (zh) * 2007-06-11 2010-03-24 和光纯药工业株式会社 微芯片大容量pcr与集成实时ce检测
WO2012049066A2 (en) * 2010-10-12 2012-04-19 Eppendorf Ag Real-time amplification and micro-array based detection of nucleic acid targets in a flow chip assay

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刘天军: "基于微喷射结构的计算机芯片冷却试验研究", 《低温与超导》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12203135B2 (en) 2012-09-26 2025-01-21 Cepheid Honeycomb tube

Also Published As

Publication number Publication date
AP2015008394A0 (en) 2015-04-30
US20180245153A1 (en) 2018-08-30
CA2886484A1 (en) 2014-04-03
CA2886484C (en) 2022-08-02
JP6525877B2 (ja) 2019-06-05
US20210164044A1 (en) 2021-06-03
WO2014052671A1 (en) 2014-04-03
MX363399B (es) 2019-03-22
JP2015532094A (ja) 2015-11-09
MX2015003859A (es) 2015-10-29
US20150275292A1 (en) 2015-10-01
ZA201502463B (en) 2019-09-25
CN111979092A (zh) 2020-11-24
AU2013323428B2 (en) 2017-11-30
US20190211396A1 (en) 2019-07-11
JP2019141092A (ja) 2019-08-29
US20240076737A1 (en) 2024-03-07
EA031989B1 (ru) 2019-03-29
US11739383B2 (en) 2023-08-29
EA201500369A1 (ru) 2015-08-31
US10767226B2 (en) 2020-09-08
US11795506B2 (en) 2023-10-24
BR112015006566B1 (pt) 2021-10-13
KR102214419B1 (ko) 2021-02-08
US20250243541A1 (en) 2025-07-31
AU2013323428A1 (en) 2015-04-16
US20210147933A1 (en) 2021-05-20
US10190165B2 (en) 2019-01-29
US9914968B2 (en) 2018-03-13
BR112015006566A2 (pt) 2017-08-08
US12281358B2 (en) 2025-04-22
US12203135B2 (en) 2025-01-21
US20240068030A1 (en) 2024-02-29
US10870884B2 (en) 2020-12-22
KR20150067222A (ko) 2015-06-17
US20250327123A1 (en) 2025-10-23
US20140087958A1 (en) 2014-03-27

Similar Documents

Publication Publication Date Title
US12281358B2 (en) Honeycomb tube
JP6718956B2 (ja) 液体循環路を制御することができる核酸増幅用の反応チューブ
CN101679932A (zh) 用于热交换化学过程的基于数字微流体的装置
US8092999B2 (en) Biological sample reaction chip and biological sample reaction method
JP2004504828A (ja) 標的核酸配列の熱依存性連鎖増幅のための装置
JP2008148690A (ja) マイクロチップを用いた核酸増幅方法およびマイクロチップ、それを用いた核酸増幅システム
JP2016185154A (ja) Pcr装置のための反応容器とpcrを行う方法
He et al. Rapid in situ photoimmobilization of a planar droplet array for digital PCR
Brennan et al. Incorporating asymmetric PCR and microarray hybridization protocols onto an integrated microfluidic device, screening for the Escherichia coli ssrA gene
JP2006223309A (ja) 化学的な増幅反応のためのマクロ多孔質支持体及びその利用
US20230043483A1 (en) High-level multiplexing reaction vessel, reagent spotting device and associated methods

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20151111

RJ01 Rejection of invention patent application after publication