CN105051178B - 用于在微生物发酵中控制代谢物产生的系统和方法 - Google Patents

用于在微生物发酵中控制代谢物产生的系统和方法 Download PDF

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CN105051178B
CN105051178B CN201480015415.4A CN201480015415A CN105051178B CN 105051178 B CN105051178 B CN 105051178B CN 201480015415 A CN201480015415 A CN 201480015415A CN 105051178 B CN105051178 B CN 105051178B
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bioreactor
fermentation
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derived
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CN105051178A (zh
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S·D·辛普森
M·科普克
K·F·斯玛特
L·P·特兰
P·西克里斯特
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Lanzatech NZ Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/145—Clostridium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Mycology (AREA)
  • Processing Of Solid Wastes (AREA)
CN201480015415.4A 2013-03-15 2014-03-12 用于在微生物发酵中控制代谢物产生的系统和方法 Active CN105051178B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361791065P 2013-03-15 2013-03-15
US61/791,065 2013-03-15
PCT/US2014/025128 WO2014151158A1 (en) 2013-03-15 2014-03-12 A system and method for controlling metabolite production in a microbial fermentation

Publications (2)

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CN105051178A CN105051178A (zh) 2015-11-11
CN105051178B true CN105051178B (zh) 2018-08-03

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US (2) US20140273115A1 (enExample)
EP (2) EP4424833A3 (enExample)
JP (4) JP6813354B2 (enExample)
KR (1) KR102157256B1 (enExample)
CN (1) CN105051178B (enExample)
BR (2) BR112015022736B1 (enExample)
CA (1) CA2903462C (enExample)
DK (1) DK2970868T3 (enExample)
EA (1) EA033028B1 (enExample)
ES (1) ES2998491T3 (enExample)
FI (1) FI2970868T3 (enExample)
MY (3) MY194094A (enExample)
SG (1) SG11201507071YA (enExample)
WO (1) WO2014151158A1 (enExample)
ZA (1) ZA201506621B (enExample)

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KR20240160674A (ko) 2014-10-22 2024-11-11 란자테크 엔지, 인크. 가스 시험 유닛 및 방법
US9873859B2 (en) * 2015-08-20 2018-01-23 H R D Corporation Microorganism growth and products recovery
GB201601558D0 (en) * 2016-01-28 2016-03-16 Verdant Bioproducts Ltd Method for producing 3-hydroxypropionamide
WO2017155478A1 (en) * 2016-03-09 2017-09-14 Ptt Public Company Limited Method for producing biochemicals from co2 fermentation
SG11201810031RA (en) * 2016-05-14 2018-12-28 Lanzatech Inc Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods
US11845969B2 (en) * 2016-09-26 2023-12-19 Sk Innovation Co., Ltd. Process of converting carbon dioxide using combination of carbon dioxide mineralization process and metabolism of sulfur-oxidizing microorganisms
MX2021014715A (es) * 2019-06-07 2022-01-18 Unibio As Metodo para optimizar un proceso de fermentacion.
KR102273179B1 (ko) * 2019-09-04 2021-07-02 한국해양과학기술원 클로스트리디움 속 신균주 awrp 및 이를 이용한 바이오 알코올의 선택적 생산방법
KR102443037B1 (ko) * 2020-10-23 2022-09-14 한국과학기술연구원 에탄올을 포함하는 합성 가스로부터 2,3-부탄디올 제조용 배지 조성물 및 이를 이용한 2,3-부탄디올 생산 방법
CN112746008B (zh) * 2021-02-05 2024-04-05 清华大学 含一氧化碳原料气发酵制含氧有机物的发酵反应器及方法
CN117120623B (zh) * 2021-04-09 2024-10-18 朗泽科技有限公司 用于改进二氧化碳转化为产物的灵活发酵平台
CN115814592A (zh) * 2022-12-19 2023-03-21 河北首朗新能源科技有限公司 一种提高工业尾气发酵利用率的方法和系统

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EA033028B1 (ru) 2019-08-30
FI2970868T3 (fi) 2024-11-29
KR20150128730A (ko) 2015-11-18
US20170342446A1 (en) 2017-11-30
EP2970868A1 (en) 2016-01-20
EA201591547A1 (ru) 2016-01-29
MY194095A (en) 2022-11-11
CA2903462C (en) 2016-11-01
KR102157256B1 (ko) 2020-09-18
BR122022024140B1 (pt) 2023-05-16
US20140273115A1 (en) 2014-09-18
ES2998491T3 (en) 2025-02-20
MY183766A (en) 2021-03-12
JP2020195383A (ja) 2020-12-10
WO2014151158A9 (en) 2015-02-26
BR112015022736B1 (pt) 2023-02-23
EP4424833A2 (en) 2024-09-04
BR112015022736A2 (enExample) 2017-08-22
JP2016511009A (ja) 2016-04-14
ZA201506621B (en) 2017-03-26
WO2014151158A1 (en) 2014-09-25
EP4424833A3 (en) 2025-09-24
JP2019122387A (ja) 2019-07-25
CN105051178A (zh) 2015-11-11
SG11201507071YA (en) 2015-10-29
DK2970868T3 (da) 2024-12-02
JP7110283B2 (ja) 2022-08-01
JP2022160489A (ja) 2022-10-19
EP2970868A4 (en) 2016-09-28
MY194094A (en) 2022-11-11
CA2903462A1 (en) 2014-09-25
EP2970868B1 (en) 2024-09-04
JP6813354B2 (ja) 2021-01-13

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