CN105039472B - 一种重组人粒细胞刺激因子多肽的纯化方法 - Google Patents
一种重组人粒细胞刺激因子多肽的纯化方法 Download PDFInfo
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- CN105039472B CN105039472B CN201510306601.XA CN201510306601A CN105039472B CN 105039472 B CN105039472 B CN 105039472B CN 201510306601 A CN201510306601 A CN 201510306601A CN 105039472 B CN105039472 B CN 105039472B
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Abstract
Description
收率 | 电泳纯度 | HPLC纯度 | 内毒素 | 比活(IU/mg) | |
实施例1 | 72.2% | 100% | 99.8% | 符合规定 | 1.5×108 |
实施例2 | 70.5% | 96.9% | 98.8% | 符合规定 | 1.3×108 |
实施例3 | 86.5% | 87.1% | 89.6% | 不符合规定 | 0.9×108 |
实施例4 | 63.7% | 96.4% | 98.2% | 符合规定 | 1.1×108 |
实施例5 | 59.9% | 96.6% | 98.5% | 符合规定 | 1.2×108 |
实施例6 | 64.2% | 94.2% | 92.6% | 符合规定 | 0.9×108 |
实施例7 | 60.4% | 96.5% | 97.4% | 符合规定 | 1.0×108 |
实施例8 | 58.2% | 95.6% | 96.7% | 符合规定 | 1.0×108 |
实施例9 | 60.7% | 96.1% | 96.8% | 符合规定 | 1.0×108 |
Claims (5)
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CN107561168A (zh) * | 2016-06-30 | 2018-01-09 | 山东新时代药业有限公司 | 一种聚乙二醇化促胰岛素分泌肽类似物的分析检测方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102796197A (zh) * | 2011-05-24 | 2012-11-28 | 杭州九源基因工程有限公司 | 一种hsa-gcsf突变体及其制备方法 |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN102796197A (zh) * | 2011-05-24 | 2012-11-28 | 杭州九源基因工程有限公司 | 一种hsa-gcsf突变体及其制备方法 |
Non-Patent Citations (1)
Title |
---|
陈斌.重组人粒细胞刺激因子纯化工艺的研究.《中国优秀硕士学位论文全文数据库•医药卫生科技辑》.2008,(第10期), * |
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