CN105031488A - Traditional Chinese medicinal composition for treating enterogastritis - Google Patents
Traditional Chinese medicinal composition for treating enterogastritis Download PDFInfo
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- CN105031488A CN105031488A CN201510383165.6A CN201510383165A CN105031488A CN 105031488 A CN105031488 A CN 105031488A CN 201510383165 A CN201510383165 A CN 201510383165A CN 105031488 A CN105031488 A CN 105031488A
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Abstract
The invention relates to a traditional Chinese medicinal composition for treating enterogastritis. The composition is prepared from, by weight, 15-25 parts of Fructus Amomi, 15-25 parts of Concha Arcae, 10-15 parts of Agrimonia eupatoria, 10-15 parts of chicken's gizzard membrane, 10-15 parts of Concha Margaritifera, 10-15 parts of Anemone chinensis, 5-10 parts of Chinese magnoliavine, 5-10 parts of Caulis Spatholobi, 5-10 parts of Acorus gramineus, 5-10 parts of perilla frutescens, 5-10 parts of ginger and 5-10 parts of Euphorbia humifusa Willd. The traditional Chinese medicinal composition has the efficacy of sterilizing and disinfecting, removing the necrotic tissues and promoting granulation, warming the middle warmer and dispelling cod, invigorating spleen and relieving diarrhea, benefiting qi and nourishing blood, and astricting and inducing astringency, can be used for treating acute and chronic enterogastritis induced by various reasons, and has no toxic side effect and a substantial treatment effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, in particular to a kind of Chinese medicine composition for the treatment of intestinal, gastritis.
Background technology
Intestinal, gastritis are a kind of commonly encountered diseases, frequently-occurring disease, though mortality rate is not high, sickness rate is high, and the chronic enteritis course of disease is the several years to many decades, the health of serious harm people.Intestinal, gastritis have acute and chronic two kinds, acute bowel, gastritis generally by improper diet, the stomach that alimentary toxicosis causes, intestinal mucosa acute inflammation.And a kind of intestinal, gastric mucosa chronic inflammatory disease that chronic intestinal, gastritis are caused by different pathogeny, sickness rate raises along with the age and raises.Chronic intestinal, gastritis can be divided into constitutional and Secondary cases two class, because Secondary cases is normal and protopathy exists simultaneously, be secondary to liver and gall diseases, cardiac insufficiency, peptic ulcer etc. more, its symptom is that the partial clinical of protopathy shows but not an independent disease, will treat protopathy during treatment simultaneously.The common nausea and vomiting of clinical manifestation, stomachache, sometimes with diarrhoea, epigastrium or umbilicus Zhou Bushi or pain, also can show as irregular paroxysmal or persistence stomachache, this can with inappetence, feel sick, abdominal distention.
Generally adopt antibiotic medicine and astringing to arrest diarrhea drug combination both at home and abroad at present, but the unsuitable long-term taking of antibiotics, improper use, causes intestinal, gastric dysbacteriosis on the contrary, causes medicamentosus diarrhea.The frequent recurrent exerbation of intestinal, gastritis, makes patient very worried, greatly have impact on the work of patient, studying and living.Empirical evidence intestinal, gastritis Western medicine are difficult to radical cure.
Intestinal, gastritis belong to the category such as the traditional Chinese medical science " stomachache ", " hypochondriac pain ", " stomachache ", " having loose bowels ".Traditional Chinese medical science aspect sees that stomach, intestinal are all burnt in place, and intercommunicate in meridians, from five elements' taste dependent territory, liver and gall belong to wood, and large intestine belongs to gold, and small intestinal belongs to fire, raw gram each other.The cause of disease of this disease, pathogenesis mostly are intemperance of taking food, taste imbalance, incoordination between the liver and stomach, stagnation of QI due to depression of the liver, weakness of the spleen and stomach, damp and hot interior life etc. to be caused middle burnt functional activity of QI being not smooth and falls ill." Plain Questions. lift a pain opinion section " say: " between the intestines and stomach, under film is former, blood must not fall apart cold-evil visitor, and little network draws urgency, therefore pain.", " Plain Questions. a numbness opinion section " say: " eating twice as usual, the intestines and stomach is wound.”。Though its cause of disease is many, its pathogeny truly has something in common, i.e. so-called " stagnation of QI and blood may bring about pain ".The hypochondriac pain cause of disease has depression of liver-QI, blood stasis is at a stop, dampness-heat in the liver and gallbladder, deficiecny of liver-YIN etc., its etiology and pathogenesis, except qi depression to blood stasis, outside straight impairing the liver gallbladder, simultaneously relevant with taste, kidney.The stomachache cause of disease has diseases caused by exogenous pathogenic factor seasonal pathogen, eating and drinking without temperance, disorder of emotion, yang-energy element empty, and pathogenesis is depression and stagnation of QI, venation numbness hinders and passages through which vital energy circulates mistake is supported.The cause of disease of having loose bowels is being invaded by exogenous pathogen, injury due to diet, disorder of emotion, weakness of the spleen and stomach, kidney yang deficiency etc., and pathogenesis is mainly not normal at spleen and stomach function.Wish to search out a kind of Chinese medicine thoroughly curing intestinal, gastric disease in conjunction with theory of Chinese medical science.
Summary of the invention
The invention provides a kind of Chinese medicine composition for the treatment of intestinal, gastritis, disinfecting detoxifying, removing the necrotic tissue and promoting granulation, warming middle-JIAO to dispel cold, invigorating the spleen to arrest diarrhea, benefiting qi and nourishing blood, restrain astringent or styptic treatment for spontaneous sweating effect, be used for the treatment of intestinal, gastritis that a variety of causes causes, patient can be improved symptom at short notice, have no side effect, therapeutic effect is remarkable.
The concrete technical scheme of the present invention is that a kind of Chinese medicine composition for the treatment of intestinal, gastritis, comprises the raw material of following weight portion: Fructus Amomi 15-25 part, Concha Arcae 15-25 part.
In the embodiment that the present invention one is concrete, described treatment intestinal, the Chinese medicine composition of gastritis, be made up of the crude drug of following weight portion: Fructus Amomi 15-25 part, Concha Arcae 15-25 part, Herba Agrimoniae 10-15 part, Endothelium Corneum Gigeriae Galli 10-15 part, Concha Margaritifera 10-15 part, Radix Pulsatillae 10-15 part, Fructus Schisandrae Chinensis 5-10 part, Caulis Spatholobi 5-10 part, Rhizoma Acori Graminei 5-10 part, Folium Perillae 5-10 part, Rhizoma Zingiberis Recens 5-10 part, Herba Euphorbiae Humifusae 5-10 part.
In the embodiment that the present invention one is concrete, described treatment intestinal, the Chinese medicine composition of gastritis, be made up of the crude drug of following weight portion: Fructus Amomi 15 parts, Concha Arcae 15 parts, Herba Agrimoniae 10 parts, Endothelium Corneum Gigeriae Galli 10 parts, Concha Margaritifera 10 parts, the Radix Pulsatillae 10 parts, Fructus Schisandrae Chinensis 5 parts, Caulis Spatholobi 5 parts, Rhizoma Acori Graminei 5 parts, Folium Perillae 5 parts, 5 parts, Rhizoma Zingiberis Recens, Herba Euphorbiae Humifusae 5 parts.
In the embodiment that the present invention one is concrete, described treatment intestinal, the Chinese medicine composition of gastritis, be made up of the crude drug of following weight portion: Fructus Amomi 25 parts, Concha Arcae 25 parts, Herba Agrimoniae 15 parts, Endothelium Corneum Gigeriae Galli 15 parts, Concha Margaritifera 15 parts, the Radix Pulsatillae 15 parts, Fructus Schisandrae Chinensis 10 parts, Caulis Spatholobi 10 parts, Rhizoma Acori Graminei 10 parts, Folium Perillae 10 parts, 10 parts, Rhizoma Zingiberis Recens, Herba Euphorbiae Humifusae 10 parts.
In the embodiment that the present invention one is concrete, described treatment intestinal, the Chinese medicine composition of gastritis, be made up of the crude drug of following weight portion: Fructus Amomi 15 parts, Concha Arcae 25 parts, Herba Agrimoniae 10 parts, Endothelium Corneum Gigeriae Galli 15 parts, Concha Margaritifera 10 parts, the Radix Pulsatillae 15 parts, Fructus Schisandrae Chinensis 5 parts, Caulis Spatholobi 10 parts, Rhizoma Acori Graminei 5 parts, Folium Perillae 10 parts, 5 parts, Rhizoma Zingiberis Recens, Herba Euphorbiae Humifusae 10 parts.
The Chinese medicine composition for the treatment of intestinal of the present invention, gastritis, can prepare according to the conventional method of the field of Chinese medicines, comprise soak by water etc.Also the conventional method of Chinese medicine preparation can be adopted to be prepared into any traditional oral preparation.Described oral formulations is capsule, pill, powder, tablet, granule etc., and especially each crude drug pulverize mix homogeneously being made capsule, to take effect orally best.
The present invention has following advantages and beneficial effect: Chinese medicine composition of the present invention has disinfecting detoxifying, removing the necrotic tissue and promoting granulation, warming middle-JIAO to dispel cold, invigorating the spleen to arrest diarrhea, benefiting qi and nourishing blood, restrains the effects such as astringent or styptic treatment for spontaneous sweating, is used for the treatment of deficiency-cold in middle-JIAO, coldness and pain in the epigastrium, cold-damp accumulating in the interior, the diseases such as the acute chronic gastroenteritis that loose stool or have loose bowels etc. shows are that one has no side effect, good effect, the good medicine of instant effect.Clinical data shows its total effective rate up to 99%.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine composition for intestinal, gastritis, be made up of the raw material of following weight portion: Fructus Amomi 15 parts, Concha Arcae 15 parts, Herba Agrimoniae 10 parts, Endothelium Corneum Gigeriae Galli 10 parts, Concha Margaritifera 10 parts, the Radix Pulsatillae 10 parts, Fructus Schisandrae Chinensis 5 parts, Caulis Spatholobi 5 parts, Rhizoma Acori Graminei 5 parts, Folium Perillae 5 parts, 5 parts, Rhizoma Zingiberis Recens, Herba Euphorbiae Humifusae 5 parts;
Each crude drug is dry at 45 DEG C, be cooled to room temperature, pulverize state, and mix homogeneously, load snap fit capsule, to obtain final product.
Embodiment 2:
Treat a Chinese medicine composition for intestinal, gastritis, be made up of the raw material of following weight portion: Fructus Amomi 15 parts, Concha Arcae 15 parts, Herba Agrimoniae 10 parts, Endothelium Corneum Gigeriae Galli 10 parts, Concha Margaritifera 10 parts, the Radix Pulsatillae 10 parts, Fructus Schisandrae Chinensis 5 parts, Caulis Spatholobi 5 parts, Rhizoma Acori Graminei 5 parts, Folium Perillae 5 parts, 5 parts, Rhizoma Zingiberis Recens, Herba Euphorbiae Humifusae 5 parts;
Take said medicine by formula ratio, be added to the water, boil, slow fire boiling 30 minutes, filter, filtering residue adds water again, slow fire boiling 30 minutes, merge twice medicinal liquid, to obtain final product.
Embodiment 3:
Treat a Chinese medicine composition for intestinal, gastritis, be made up of the raw material of following weight portion: Fructus Amomi 25 parts, Concha Arcae 25 parts, Herba Agrimoniae 15 parts, Endothelium Corneum Gigeriae Galli 15 parts, Concha Margaritifera 15 parts, the Radix Pulsatillae 15 parts, Fructus Schisandrae Chinensis 10 parts, Caulis Spatholobi 10 parts, Rhizoma Acori Graminei 10 parts, Folium Perillae 10 parts, 10 parts, Rhizoma Zingiberis Recens, Herba Euphorbiae Humifusae 10 parts;
Take said medicine by formula ratio, be added to the water, boil, slow fire boiling 30 minutes, filter, filtering residue adds water again, slow fire boiling 30 minutes, merge twice medicinal liquid, to obtain final product.
Embodiment 4:
Treat a Chinese medicine composition for intestinal, gastritis, be made up of the raw material of following weight portion: Fructus Amomi 15 parts, Concha Arcae 25 parts, Herba Agrimoniae 10 parts, Endothelium Corneum Gigeriae Galli 15 parts, Concha Margaritifera 10 parts, the Radix Pulsatillae 15 parts, Fructus Schisandrae Chinensis 5 parts, Caulis Spatholobi 10 parts, Rhizoma Acori Graminei 5 parts, Folium Perillae 10 parts, 5 parts, Rhizoma Zingiberis Recens, Herba Euphorbiae Humifusae 10 parts;
Take said medicine by formula ratio, be added to the water, boil, slow fire boiling 30 minutes, filter, filtering residue adds water again, slow fire boiling 30 minutes, merge twice medicinal liquid, to obtain final product.
Embodiment 5: the antiinflammatory action of Chinese medicine composition of the present invention
Prepared by experimental drug: Aspirin Enteric-coated Tablets, and Xuzhou Enhua Pharmaceutical Industry Group Corp., Ltd produces, every sheet 50mg, and experiment is made into the concentration of 13mg/ml with 0.5% sodium carboxymethyl cellulose; The Chinese medicine composition of the embodiment of the present invention 1, capsule 's content adding distil water makes 90mg/ml concentration.
Laboratory animal: SD rat, body weight 220 ~ 300g, male and female half and half, male mice in kunming, body weight 26 ~ 30g.Experimental technique: get healthy mice 60, be divided into 3 groups at random, often organizes 20, male and female half and half.According to " study of tcm new drug guide-pharmacology " method modeling, observe blank (normal saline), aspirin group and Chinese medicine composition group of the present invention to the impact of mice auricle swelling model, the data obtained statistical method carries out t inspection, the results are shown in Table 1.
Table 1 antiphlogistic effects of the present invention
| Group | Number of animals (only) | Dosage (g/kg) | Swelling (mg) |
| Blank | 20 | —— | 14.50±6.48 |
| Aspirin group | 20 | 0.2g | 8.23±3.23 ** |
| Chinese medicine composition group of the present invention | 20 | 2.0g | 7.57±3.19 ** |
Note: compare with blank group, * P < 0.05, * * P < 0.01
Experimental result shows that Chinese medicine composition of the present invention and aspirin group all have obvious inhibitory action to mice ear, difference has statistical significance (* * P < 0.01), shows Chinese medicine composition of the present invention and has obvious inhibitory action to acute exudative inflammation.
Embodiment 6: the clinical observation on the therapeutic effect of Chinese medicine composition of the present invention
1, physical data
Selection of clinical patient 400 example, wherein man 200 example, female 200 example, wherein 30-40 year 100 example, 41-45 year 100 example, 46-50 year 100 example, 51-60 year 100 example.
2, diagnostic criteria
Cure: inflammation all disappears, recover normal completely, and confirmed for CT or intestinal, gastroscopy, stool shaping or one-tenth soft stool, every day 1-2 time, without mucosanguineous feces.
Effective: symptom is improved in various degree or taken a turn for the better, medication treatment need be continued.
Invalid: symptom is without any improvement or take a turn for the better, and even has development trend.
3, Therapeutic Method
Adopt the capsule made of embodiment 1, every containing crude drug 1g, every day is early, middle and late respectively takes one to patient, within 15 days, is a course for the treatment of, minimumly takes 3 courses for the treatment of.
4, therapeutic outcome
Cure 238 examples, cure rate 59.5%; Effective 158 examples, effective percentage 39.5%; Invalid 4 examples, inefficiency 1.0%.
Claims (7)
1. treat a Chinese medicine composition for intestinal, gastritis, comprise the raw material of following weight portion: Fructus Amomi 15-25 part, Concha Arcae 15-25 part.
2. the Chinese medicine composition for the treatment of intestinal according to claim 1, gastritis, is made up of the crude drug of following weight portion: Fructus Amomi 15-25 part, Concha Arcae 15-25 part, Herba Agrimoniae 10-15 part, Endothelium Corneum Gigeriae Galli 10-15 part, Concha Margaritifera 10-15 part, Radix Pulsatillae 10-15 part, Fructus Schisandrae Chinensis 5-10 part, Caulis Spatholobi 5-10 part, Rhizoma Acori Graminei 5-10 part, Folium Perillae 5-10 part, Rhizoma Zingiberis Recens 5-10 part, Herba Euphorbiae Humifusae 5-10 part.
3. the Chinese medicine composition for the treatment of intestinal according to claim 1, gastritis, is made up of the crude drug of following weight portion: Fructus Amomi 15 parts, Concha Arcae 15 parts, Herba Agrimoniae 10 parts, Endothelium Corneum Gigeriae Galli 10 parts, Concha Margaritifera 10 parts, the Radix Pulsatillae 10 parts, Fructus Schisandrae Chinensis 5 parts, Caulis Spatholobi 5 parts, Rhizoma Acori Graminei 5 parts, Folium Perillae 5 parts, 5 parts, Rhizoma Zingiberis Recens, Herba Euphorbiae Humifusae 5 parts.
4. the Chinese medicine composition for the treatment of intestinal according to claim 1, gastritis, is made up of the crude drug of following weight portion: Fructus Amomi 25 parts, Concha Arcae 25 parts, Herba Agrimoniae 15 parts, Endothelium Corneum Gigeriae Galli 15 parts, Concha Margaritifera 15 parts, the Radix Pulsatillae 15 parts, Fructus Schisandrae Chinensis 10 parts, Caulis Spatholobi 10 parts, Rhizoma Acori Graminei 10 parts, Folium Perillae 10 parts, 10 parts, Rhizoma Zingiberis Recens, Herba Euphorbiae Humifusae 10 parts.
5. the Chinese medicine composition for the treatment of intestinal according to claim 1, gastritis, is made up of the crude drug of following weight portion: Fructus Amomi 15 parts, Concha Arcae 25 parts, Herba Agrimoniae 10 parts, Endothelium Corneum Gigeriae Galli 15 parts, Concha Margaritifera 10 parts, the Radix Pulsatillae 15 parts, Fructus Schisandrae Chinensis 5 parts, Caulis Spatholobi 10 parts, Rhizoma Acori Graminei 5 parts, Folium Perillae 10 parts, 5 parts, Rhizoma Zingiberis Recens, Herba Euphorbiae Humifusae 10 parts.
6. the treatment intestinal described in any one of claim 1-5, the Chinese medicine composition of gastritis, is characterized in that, adopts the conventional method of Chinese medicine preparation to be prepared into any traditional oral preparation.
7. the Chinese medicine composition for the treatment of intestinal according to claim 6, gastritis, is characterized in that, described oral formulations is capsule, pill, powder, tablet, granule.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105381449A (en) * | 2015-12-31 | 2016-03-09 | 毛春梅 | Traditional Chinese medicine composition for treating enterogastritis |
| CN105396107A (en) * | 2015-12-14 | 2016-03-16 | 青岛市市立医院 | Traditional Chinese medicine composition for curing gastroenteritis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103182065A (en) * | 2013-03-27 | 2013-07-03 | 朱新华 | Oral liquid for treating gastric and duodenal ulcer efficiently |
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- 2015-07-02 CN CN201510383165.6A patent/CN105031488A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103182065A (en) * | 2013-03-27 | 2013-07-03 | 朱新华 | Oral liquid for treating gastric and duodenal ulcer efficiently |
Non-Patent Citations (2)
| Title |
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| 李金全: "调脾益胃汤治疗慢性浅表性胃炎80例", 《山东中医杂志》 * |
| 杨华: "香砂六君子汤应用体会", 《甘肃中医学院学报》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105396107A (en) * | 2015-12-14 | 2016-03-16 | 青岛市市立医院 | Traditional Chinese medicine composition for curing gastroenteritis |
| CN105381449A (en) * | 2015-12-31 | 2016-03-09 | 毛春梅 | Traditional Chinese medicine composition for treating enterogastritis |
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Application publication date: 20151111 |