CN105396107A - Traditional Chinese medicine composition for curing gastroenteritis - Google Patents

Traditional Chinese medicine composition for curing gastroenteritis Download PDF

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Publication number
CN105396107A
CN105396107A CN201510932333.2A CN201510932333A CN105396107A CN 105396107 A CN105396107 A CN 105396107A CN 201510932333 A CN201510932333 A CN 201510932333A CN 105396107 A CN105396107 A CN 105396107A
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parts
herba
radix
chinese medicine
folium
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丁红云
隋牮箐
李光辉
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Qingdao Municipal Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/9068Zingiber, e.g. garden ginger

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Abstract

The invention relates to a traditional Chinese medicine composition for curing gastroenteritis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15-35 parts of humifuse euphorbia herb, 10-30 parts of purple perilla, 10-20 parts of bamboo shavings, 10-20 parts of capillary artemisia, 15-30 parts of fructus evodiae, 10-20 parts of folium eucalypti, 5-20 parts of psidium guajava leaves, 5-15 parts of purslane, 10-20 parts of raw ginger, 5-15 parts of platycladus orientalis leaves, 5-15 parts of corn stigma, 5-15 parts of buckwheat leaves, 10-30 parts of woolystalk wormwood, 10-20 parts of brucea javanica, 10-20 parts of Chinese pulsatilla root, 5-15 parts of carpetweed, 5-10 parts of rhizoma et radix ligustici, 5-15 parts of radix rhapontied, 10-20 parts of common threewingnut root, 10-20 parts of herba centipedae, 5-15 parts of phyllanthus urinaria, and 5-15 parts of rhizoma corydalis. The traditional Chinese medicine composition has the efficacies of sterilizing and detoxifying, removing necrotic tissues and promoting granulation, warming the middle energizer to dispel cold, tonifying spleen to stop diarrhea, replenishing qi and nourishing blood, and restraining and inducing astringency, and is used for treatment of acute and chronic enteritis and gastritis caused by a variety of reasons, has no toxic or side effects, and has remarkable treatment effect.

Description

A kind of Chinese medicine composition for the treatment of gastroenteritis
Technical field
The present invention relates to a kind of pharmaceutical composition, in particular to a kind of Chinese medicine composition for the treatment of gastroenteritis.
Background technology
Gastroenteritis is a kind of commonly encountered diseases, frequently-occurring disease, though mortality rate is not high, sickness rate is high, and the chronic enteritis course of disease is the several years to many decades, the health of serious harm people.Acute gastroenteritis generally by improper diet, the stomach that alimentary toxicosis causes, intestinal mucosa acute inflammation.And a kind of intestinal, gastric mucosa chronic inflammatory disease that chronic enterogastritis is caused by different pathogeny, sickness rate raises along with the age and raises.Chronic intestinal, gastritis can be divided into constitutional and Secondary cases two class, because Secondary cases is normal and protopathy exists simultaneously, be secondary to liver and gall diseases, cardiac insufficiency, peptic ulcer etc. more, its symptom is that the partial clinical of protopathy shows but not an independent disease, will treat protopathy during treatment simultaneously.The common nausea and vomiting of clinical manifestation, stomachache, sometimes with diarrhoea, epigastrium or umbilicus Zhou Bushi or pain, also can show as irregular paroxysmal or persistence stomachache, this can with inappetence, feel sick, abdominal distention.
Intestinal, gastritis belong to the category such as the traditional Chinese medical science " stomachache ", " hypochondriac pain ", " stomachache ", " having loose bowels " " intestinal is warded off ".Traditional Chinese medical science aspect sees that stomach, intestinal are all burnt in place, and intercommunicate in meridians, from five elements' taste dependent territory, liver and gall belong to wood, and large intestine belongs to gold, and small intestinal belongs to fire, raw gram each other." Zhengzi Huibu " is pointed out: " the intestinal person of warding off, call and damp and hotly amass in intestinal, namely modern gastroenteritis also, therefore say not become to rush down without disease, rush down be wet, heat, food stagnation three ".Treatment should be taked the method for determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, Jing-Yue Complete Works cloud: " allly control gastroenteritis, when examining deficiency and excess, distinguish cold and heat, this rushes down maximum relation, if four fail to understand, then kills a person very easily also.", therefore the dialectical head of primary disease distinguishes cold, hot, empty, reality, faces card and works as according to stomachache, tenesmus, rushes down color, and refer and synthesize tongue arteries and veins and distinguish.
Generally adopt antibiotic medicine and astringing to arrest diarrhea drug combination both at home and abroad at present, but the unsuitable long-term taking of antibiotics, improper use, causes intestinal, gastric dysbacteriosis on the contrary, causes medicamentosus diarrhea.The frequent recurrent exerbation of intestinal, gastritis, makes patient very worried, greatly have impact on the work of patient, studying and living.Empirical evidence intestinal, gastritis Western medicine are difficult to radical cure.
Summary of the invention
The invention provides a kind of Chinese medicine composition for the treatment of functional gastrointestinal inflammation, there is disinfecting detoxifying, removing the necrotic tissue and promoting granulation, warming middle-JIAO to dispel cold, invigorating the spleen to arrest diarrhea, benefiting qi and nourishing blood, restrains astringent or styptic treatment for spontaneous sweating effect, is used for the treatment of acute and chronic intestinal, gastritis that a variety of causes causes, have no side effect, therapeutic effect is remarkable.
Concrete, one aspect of the present invention provides a kind of Chinese medicine composition for the treatment of gastroenteritis, be made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 15-35 part, Folium Perillae 10-30 part, Caulis Bambusae In Taenia 10-20 part, Herba Artemisiae Scopariae 10-20 part, Fructus Evodiae 15-30 part, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10-20 part, Folium Psidii Guajavae 5-20 part, Herba Portulacae 5-15 part, Rhizoma Zingiberis Recens 10-20 part, Cacumen Platycladi 5-15 part, Stigma Maydis 5-15 part, buckwheat leaf 5-15 part, Artemisia eriopoda Bunge. 10-30 part, Fructus Bruceae 10-20 part, Radix Pulsatillae 10-20 part, carpet weed 5-15 part, Rhizoma Ligustici 5-10 part, Radix Rhapontici 5-15 part, Radix Tripterygii Wilfordii 10-20 part, Herba Centipedae 10-20 part, Cacumen Securinegae Suffruticosae 5-15 part, Rhizoma Corydalis 5-15 part.
In the embodiment that the present invention one is concrete, a kind of Chinese medicine composition for the treatment of gastroenteritis is made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 15-25 part, Folium Perillae 10-20 part, Caulis Bambusae In Taenia 10-20 part, Herba Artemisiae Scopariae 10-20 part, Fructus Evodiae 15-25 part, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10-15 part, Folium Psidii Guajavae 5-15 part, Herba Portulacae 5-10 part, Rhizoma Zingiberis Recens 10-15 part, Cacumen Platycladi 5-10 part, Stigma Maydis 5-10 part, buckwheat leaf 5-15 part, Artemisia eriopoda Bunge. 10-20 part, Fructus Bruceae 10-15 part, Radix Pulsatillae 10-15 part, carpet weed 5-10 part, Rhizoma Ligustici 5-10 part, Radix Rhapontici 5-15 part, Radix Tripterygii Wilfordii 10-15 part, Herba Centipedae 10-15 part, Cacumen Securinegae Suffruticosae 5-10 part, Rhizoma Corydalis 5-10 part.
In the embodiment that the present invention one is concrete, a kind of Chinese medicine composition for the treatment of gastroenteritis is made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 20-35 part, Folium Perillae 20-30 part, Caulis Bambusae In Taenia 15-20 part, Herba Artemisiae Scopariae 15-20 part, Fructus Evodiae 20-30 part, Folium eucalypti globueli (Eucalyptus globulus Labill.) 15-20 part, Folium Psidii Guajavae 10-20 part, Herba Portulacae 10-15 part, Rhizoma Zingiberis Recens 15-20 part, Cacumen Platycladi 10-15 part, Stigma Maydis 10-15 part, buckwheat leaf 10-15 part, Artemisia eriopoda Bunge. 20-30 part, Fructus Bruceae 15-20 part, Radix Pulsatillae 15-20 part, carpet weed 10-15 part, Rhizoma Ligustici 5-10 part, Radix Rhapontici 10-15 part, Radix Tripterygii Wilfordii 15-20 part, Herba Centipedae 15-20 part, Cacumen Securinegae Suffruticosae 10-15 part, Rhizoma Corydalis 10-15 part.
In the embodiment that the present invention one is concrete, a kind of Chinese medicine composition for the treatment of gastroenteritis is made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 35 parts, Folium Perillae 30 parts, Caulis Bambusae In Taenia 20 parts, Herba Artemisiae Scopariae 20 parts, Fructus Evodiae 30 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 20 parts, Folium Psidii Guajavae 20 parts, Herba Portulacae 15 parts, 20 parts, Rhizoma Zingiberis Recens, Cacumen Platycladi 15 parts, Stigma Maydis 15 parts, buckwheat leaf 15 parts, Artemisia eriopoda Bunge. 30 parts, Fructus Bruceae 20 parts, the Radix Pulsatillae 20 parts, carpet weed 15 parts, Rhizoma Ligustici 10 parts, Radix Rhapontici 15 parts, Radix Tripterygii Wilfordii 20 parts, Herba Centipedae 20 parts, Cacumen Securinegae Suffruticosae 15 parts, Rhizoma Corydalis 15 parts.
In the embodiment that the present invention one is concrete, a kind of Chinese medicine composition for the treatment of gastroenteritis is made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 15 parts, Folium Perillae 10 parts, Caulis Bambusae In Taenia 10 parts, Herba Artemisiae Scopariae 10 parts, Fructus Evodiae 15 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 parts, Folium Psidii Guajavae 5 parts, Herba Portulacae 5 parts, 10 parts, Rhizoma Zingiberis Recens, Cacumen Platycladi 5 parts, Stigma Maydis 5 parts, buckwheat leaf 5 parts, Artemisia eriopoda Bunge. 10 parts, Fructus Bruceae 10 parts, the Radix Pulsatillae 10 parts, carpet weed 5 parts, Rhizoma Ligustici 5 parts, Radix Rhapontici 5 parts, Radix Tripterygii Wilfordii 10 parts, Herba Centipedae 10 parts, Cacumen Securinegae Suffruticosae 5 parts, Rhizoma Corydalis 5 parts.
In the embodiment that the present invention one is concrete, a kind of Chinese medicine composition for the treatment of gastroenteritis is made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 35 parts, Folium Perillae 10 parts, Caulis Bambusae In Taenia 20 parts, Herba Artemisiae Scopariae 10 parts, Fructus Evodiae 30 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 parts, Folium Psidii Guajavae 20 parts, Herba Portulacae 5 parts, 20 parts, Rhizoma Zingiberis Recens, Cacumen Platycladi 5 parts, Stigma Maydis 15 parts, buckwheat leaf 5 parts, Artemisia eriopoda Bunge. 30 parts, Fructus Bruceae 10 parts, the Radix Pulsatillae 20 parts, carpet weed 5 parts, Rhizoma Ligustici 10 parts, Radix Rhapontici 5 parts, Radix Tripterygii Wilfordii 20 parts, Herba Centipedae 10 parts, Cacumen Securinegae Suffruticosae 15 parts, Rhizoma Corydalis 5 parts.
In the embodiment that the present invention one is concrete, a kind of Chinese medicine composition for the treatment of gastroenteritis is made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 25 parts, Folium Perillae 20 parts, Caulis Bambusae In Taenia 15 parts, Herba Artemisiae Scopariae 15 parts, Fructus Evodiae 23 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 14 parts, Folium Psidii Guajavae 13 parts, Herba Portulacae 10 parts, 15 parts, Rhizoma Zingiberis Recens, Cacumen Platycladi 10 parts, Stigma Maydis 10 parts, buckwheat leaf 10 parts, Artemisia eriopoda Bunge. 20 parts, Fructus Bruceae 15 parts, the Radix Pulsatillae 15 parts, carpet weed 10 parts, Rhizoma Ligustici 8 parts, Radix Rhapontici 10 parts, Radix Tripterygii Wilfordii 15 parts, Herba Centipedae 15 parts, Cacumen Securinegae Suffruticosae 10 parts, Rhizoma Corydalis 12 parts.
The present invention provides a kind of preparation method for the treatment of the Chinese medicine composition of gastroenteritis on the other hand, and it is characterized in that, the preparation method of this pharmaceutical composition comprises the following steps:
(1) Herba Euphorbiae Humifusae, Folium Perillae, Fructus Evodiae, Folium Psidii Guajavae, Rhizoma Zingiberis Recens, Stigma Maydis, Artemisia eriopoda Bunge., the Radix Pulsatillae, Rhizoma Ligustici, Radix Tripterygii Wilfordii, Cacumen Securinegae Suffruticosae, Rhizoma Corydalis are added soak by water 2-3 time accounting for gross weight 8-15 times amount, each 1.5-2 hour, collecting decoction, add the aqueous solution that step (1) obtains again, filter, relative density when filtrate is concentrated into 80 DEG C is the extractum (I) of 1.15-1.25;
(2) Caulis Bambusae In Taenia, Herba Artemisiae Scopariae, Folium eucalypti globueli (Eucalyptus globulus Labill.), Herba Portulacae, Cacumen Platycladi, buckwheat leaf, Fructus Bruceae, carpet weed, Radix Rhapontici, Herba Centipedae are added account for gross weight 8-15 times amount 85% alcoholic solution in extract 2-3 time, each 2-3 hour, filter, merging filtrate, placement is spent the night, reclaim ethanol, relative density when filtrate being concentrated into 60 DEG C is the extractum (II) of 1.15-1.25; (3) in step (1), the mixing of (2) gained extractum, dry, stir, to obtain final product.
In a concrete embodiment of the present invention, wherein add the soak by water 3 times accounting for gross weight 10 times amount in step (1), each 1.5 hours; Account in step (2) in the alcoholic solution of 85% of gross weight 10 times amount and extract 2 times, each 3 hours.
The Chinese medicine composition for the treatment of gastroenteritis of the present invention, also can prepare according to the conventional method of the field of Chinese medicines, comprises soak by water, by each crude drug pulverize etc.The conventional method of Chinese medicine preparation can be adopted to be prepared into any traditional oral preparation.Described oral formulations is capsule, pill, powder, tablet, dispersible tablet, granule.
Pharmaceutical composition of the present invention, based on the dialectical prescription of tcm theory, based on the dialectical prescription of tcm theory, there is disinfecting detoxifying, removing the necrotic tissue and promoting granulation, warming middle-JIAO to dispel cold, invigorating the spleen to arrest diarrhea, benefiting qi and nourishing blood, restrain astringent or styptic treatment for spontaneous sweating effect, be used for the treatment of acute and chronic intestinal, gastritis that a variety of causes causes, have no side effect, therapeutic effect is remarkable.
Detailed description of the invention
Embodiment 1:
The Chinese medicine composition for the treatment of gastroenteritis is made up of the crude drug of following weight portion: a Herba Euphorbiae Humifusae 35g, Folium Perillae 30g, Caulis Bambusae In Taenia 20g, Herba Artemisiae Scopariae 20g, Fructus Evodiae 30g, Folium eucalypti globueli (Eucalyptus globulus Labill.) 20g, Folium Psidii Guajavae 20g, Herba Portulacae 15g, Rhizoma Zingiberis Recens 20g, Cacumen Platycladi 15g, Stigma Maydis 15g, buckwheat leaf 15g, Artemisia eriopoda Bunge. 30g, Fructus Bruceae 20g, Radix Pulsatillae 20g, carpet weed 15g, Rhizoma Ligustici 10g, Radix Rhapontici 15g, Radix Tripterygii Wilfordii 20g, Herba Centipedae 20g, Cacumen Securinegae Suffruticosae 15g, Rhizoma Corydalis 15g;
Each crude drug is dry at 45 DEG C, be cooled to room temperature, pulverize state, and mix homogeneously, load snap fit capsule, to obtain final product.
Embodiment 2:
The Chinese medicine composition for the treatment of gastroenteritis is made up of the crude drug of following weight portion: a Herba Euphorbiae Humifusae 15g, Folium Perillae 10g, Caulis Bambusae In Taenia 10g, Herba Artemisiae Scopariae 10g, Fructus Evodiae 15g, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10g, Folium Psidii Guajavae 5g, Herba Portulacae 5g, Rhizoma Zingiberis Recens 10g, Cacumen Platycladi 5g, Stigma Maydis 5g, buckwheat leaf 5g, Artemisia eriopoda Bunge. 10g, Fructus Bruceae 10g, Radix Pulsatillae 10g, carpet weed 5g, Rhizoma Ligustici 5g, Radix Rhapontici 5g, Radix Tripterygii Wilfordii 10g, Herba Centipedae 10g, Cacumen Securinegae Suffruticosae 5g, Rhizoma Corydalis 5g;
Take said medicine by formula ratio, be added to the water, boil, slow fire boiling 30 minutes, filter, filtering residue adds water again, slow fire boiling 30 minutes, merge twice medicinal liquid, to obtain final product.
Embodiment 3:
The Chinese medicine composition for the treatment of gastroenteritis is made up of the crude drug of following weight portion: a Herba Euphorbiae Humifusae 35g, Folium Perillae 10g, Caulis Bambusae In Taenia 20g, Herba Artemisiae Scopariae 10g, Fructus Evodiae 30g, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10g, Folium Psidii Guajavae 20g, Herba Portulacae 5g, Rhizoma Zingiberis Recens 20g, Cacumen Platycladi 5g, Stigma Maydis 15g, buckwheat leaf 5g, Artemisia eriopoda Bunge. 30g, Fructus Bruceae 10g, Radix Pulsatillae 20g, carpet weed 5g, Rhizoma Ligustici 10g, Radix Rhapontici 5g, Radix Tripterygii Wilfordii 20g, Herba Centipedae 10g, Cacumen Securinegae Suffruticosae 15g, Rhizoma Corydalis 5g;
Preparation method comprises the following steps:
(1) Herba Euphorbiae Humifusae, Folium Perillae, Fructus Evodiae, Folium Psidii Guajavae, Rhizoma Zingiberis Recens, Stigma Maydis, Artemisia eriopoda Bunge., the Radix Pulsatillae, Rhizoma Ligustici, Radix Tripterygii Wilfordii, Cacumen Securinegae Suffruticosae, Rhizoma Corydalis are added the soak by water 3 times accounting for gross weight 10 times amount, each 2 hours, collecting decoction, add the aqueous solution that step (1) obtains again, filter, relative density when filtrate is concentrated into 80 DEG C is the extractum (I) of 1.15-1.25;
(2) Caulis Bambusae In Taenia, Herba Artemisiae Scopariae, Folium eucalypti globueli (Eucalyptus globulus Labill.), Herba Portulacae, Cacumen Platycladi, buckwheat leaf, Fructus Bruceae, carpet weed, Radix Rhapontici, Herba Centipedae are added account for gross weight 10 times amount 85% alcoholic solution in extract 3 times, each 3 hours, filter, merging filtrate, placement is spent the night, reclaim ethanol, relative density when filtrate being concentrated into 60 DEG C is the extractum (II) of 1.15-1.25;
(3) in step (1), the mixing of (2) gained extractum, dry, stir, incapsulate and get final product.
Embodiment 4:
The Chinese medicine composition for the treatment of gastroenteritis is made up of the crude drug of following weight portion: a Herba Euphorbiae Humifusae 25g, Folium Perillae 20g, Caulis Bambusae In Taenia 15g, Herba Artemisiae Scopariae 15g, Fructus Evodiae 23g, Folium eucalypti globueli (Eucalyptus globulus Labill.) 14g, Folium Psidii Guajavae 13g, Herba Portulacae 10g, Rhizoma Zingiberis Recens 15g, Cacumen Platycladi 10g, Stigma Maydis 10g, buckwheat leaf 10g, Artemisia eriopoda Bunge. 20g, Fructus Bruceae 15g, Radix Pulsatillae 15g, carpet weed 10g, Rhizoma Ligustici 8g, Radix Rhapontici 10g, Radix Tripterygii Wilfordii 15g, Herba Centipedae 15g, Cacumen Securinegae Suffruticosae 10g, Rhizoma Corydalis 12g;
Take said medicine by formula ratio, be added to the water, boil, slow fire boiling 30 minutes, filter, filtering residue adds water again, slow fire boiling 30 minutes, merge twice medicinal liquid, to obtain final product.
The antiinflammatory action of embodiment 5 Chinese medicine composition of the present invention
Prepared by experimental drug: Aspirin Enteric-coated Tablets, and Xuzhou Enhua Pharmaceutical Industry Group Corp., Ltd produces, and every sheet 50mg, is made into the concentration of 13mg/ml with 0.5% sodium carboxymethyl cellulose; The Chinese medicine composition of the embodiment of the present invention 1, capsule 's content adding distil water makes 90mg/ml concentration.
Laboratory animal: SD rat, body weight 220 ~ 300g, male and female half and half, male mice in kunming, body weight 26 ~ 30g.Experimental technique: get healthy mice 60, be divided into 3 groups at random, often organizes 20, male and female half and half.According to " study of tcm new drug guide-pharmacology " method modeling, observe blank (normal saline), aspirin group and Chinese medicine composition group of the present invention to the impact of mice auricle swelling model, the data obtained statistical method carries out t inspection, the results are shown in Table 1.
Table 1 antiphlogistic effects of the present invention
Group Number of animals (only) Dosage (g/kg) Swelling (mg)
Blank 20 —— 14.68±6.35
Aspirin group 20 0.2g 8.18±3.21 **
Chinese medicine composition group of the present invention 20 2.0g 8.07±3.17 **
Note: compare with blank group, * P < 0.05, * * P < 0.01
Experimental result shows that Chinese medicine composition of the present invention and aspirin group all have obvious inhibitory action to mice ear, difference has statistical significance (* * P < 0.01), shows Chinese medicine composition of the present invention and has obvious inhibitory action to acute exudative inflammation.
Embodiment 6: the clinical observation on the therapeutic effect of Chinese medicine composition of the present invention
1, physical data
Selection of clinical patient 200 example, wherein man 100 example, female 100 example.
2, diagnostic criteria
Cure: inflammation all disappears, recover normal completely, and confirmed for CT or intestinal, gastroscopy, stool shaping or one-tenth soft stool, every day 1-2 time, without mucosanguineous feces.
Effective: symptom is improved in various degree or taken a turn for the better, medication treatment need be continued.
Invalid: symptom is without any improvement or take a turn for the better, and even has development trend.
3, Therapeutic Method
Adopt the capsule made of embodiment 3, every containing crude drug 1g, every day is early, middle and late respectively takes one to patient, within 15 days, is a course for the treatment of, minimumly takes 3 courses for the treatment of.
4, therapeutic outcome
Cure 110 examples, cure rate 55%; Effective 84 examples, effective percentage 42%; Invalid 6 examples.All there is not any untoward reaction in all cases.

Claims (9)

1. treat the Chinese medicine composition of gastroenteritis for one kind, be made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 15-35 part, Folium Perillae 10-30 part, Caulis Bambusae In Taenia 10-20 part, Herba Artemisiae Scopariae 10-20 part, Fructus Evodiae 15-30 part, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10-20 part, Folium Psidii Guajavae 5-20 part, Herba Portulacae 5-15 part, Rhizoma Zingiberis Recens 10-20 part, Cacumen Platycladi 5-15 part, Stigma Maydis 5-15 part, buckwheat leaf 5-15 part, Artemisia eriopoda Bunge. 10-30 part, Fructus Bruceae 10-20 part, Radix Pulsatillae 10-20 part, carpet weed 5-15 part, Rhizoma Ligustici 5-10 part, Radix Rhapontici 5-15 part, Radix Tripterygii Wilfordii 10-20 part, Herba Centipedae 10-20 part, Cacumen Securinegae Suffruticosae 5-15 part, Rhizoma Corydalis 5-15 part.
2. a kind of Chinese medicine composition for the treatment of gastroenteritis according to claim 1, be made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 15-25 part, Folium Perillae 10-20 part, Caulis Bambusae In Taenia 10-20 part, Herba Artemisiae Scopariae 10-20 part, Fructus Evodiae 15-25 part, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10-15 part, Folium Psidii Guajavae 5-15 part, Herba Portulacae 5-10 part, Rhizoma Zingiberis Recens 10-15 part, Cacumen Platycladi 5-10 part, Stigma Maydis 5-10 part, buckwheat leaf 5-15 part, Artemisia eriopoda Bunge. 10-20 part, Fructus Bruceae 10-15 part, Radix Pulsatillae 10-15 part, carpet weed 5-10 part, Rhizoma Ligustici 5-10 part, Radix Rhapontici 5-15 part, Radix Tripterygii Wilfordii 10-15 part, Herba Centipedae 10-15 part, Cacumen Securinegae Suffruticosae 5-10 part, Rhizoma Corydalis 5-10 part.
3. a kind of Chinese medicine composition for the treatment of gastroenteritis according to claim 1, be made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 20-35 part, Folium Perillae 20-30 part, Caulis Bambusae In Taenia 15-20 part, Herba Artemisiae Scopariae 15-20 part, Fructus Evodiae 20-30 part, Folium eucalypti globueli (Eucalyptus globulus Labill.) 15-20 part, Folium Psidii Guajavae 10-20 part, Herba Portulacae 10-15 part, Rhizoma Zingiberis Recens 15-20 part, Cacumen Platycladi 10-15 part, Stigma Maydis 10-15 part, buckwheat leaf 10-15 part, Artemisia eriopoda Bunge. 20-30 part, Fructus Bruceae 15-20 part, Radix Pulsatillae 15-20 part, carpet weed 10-15 part, Rhizoma Ligustici 5-10 part, Radix Rhapontici 10-15 part, Radix Tripterygii Wilfordii 15-20 part, Herba Centipedae 15-20 part, Cacumen Securinegae Suffruticosae 10-15 part, Rhizoma Corydalis 10-15 part.
4. a kind of Chinese medicine composition for the treatment of gastroenteritis according to claim 1, is made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 35 parts, Folium Perillae 30 parts, Caulis Bambusae In Taenia 20 parts, Herba Artemisiae Scopariae 20 parts, Fructus Evodiae 30 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 20 parts, Folium Psidii Guajavae 20 parts, Herba Portulacae 15 parts, 20 parts, Rhizoma Zingiberis Recens, Cacumen Platycladi 15 parts, Stigma Maydis 15 parts, buckwheat leaf 15 parts, Artemisia eriopoda Bunge. 30 parts, Fructus Bruceae 20 parts, the Radix Pulsatillae 20 parts, carpet weed 15 parts, Rhizoma Ligustici 10 parts, Radix Rhapontici 15 parts, Radix Tripterygii Wilfordii 20 parts, Herba Centipedae 20 parts, Cacumen Securinegae Suffruticosae 15 parts, Rhizoma Corydalis 15 parts.
5. a kind of Chinese medicine composition for the treatment of gastroenteritis according to claim 1, is made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 15 parts, Folium Perillae 10 parts, Caulis Bambusae In Taenia 10 parts, Herba Artemisiae Scopariae 10 parts, Fructus Evodiae 15 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 parts, Folium Psidii Guajavae 5 parts, Herba Portulacae 5 parts, 10 parts, Rhizoma Zingiberis Recens, Cacumen Platycladi 5 parts, Stigma Maydis 5 parts, buckwheat leaf 5 parts, Artemisia eriopoda Bunge. 10 parts, Fructus Bruceae 10 parts, the Radix Pulsatillae 10 parts, carpet weed 5 parts, Rhizoma Ligustici 5 parts, Radix Rhapontici 5 parts, Radix Tripterygii Wilfordii 10 parts, Herba Centipedae 10 parts, Cacumen Securinegae Suffruticosae 5 parts, Rhizoma Corydalis 5 parts.
6. a kind of Chinese medicine composition for the treatment of gastroenteritis according to claim 1, is made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 35 parts, Folium Perillae 10 parts, Caulis Bambusae In Taenia 20 parts, Herba Artemisiae Scopariae 10 parts, Fructus Evodiae 30 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 parts, Folium Psidii Guajavae 20 parts, Herba Portulacae 5 parts, 20 parts, Rhizoma Zingiberis Recens, Cacumen Platycladi 5 parts, Stigma Maydis 15 parts, buckwheat leaf 5 parts, Artemisia eriopoda Bunge. 30 parts, Fructus Bruceae 10 parts, the Radix Pulsatillae 20 parts, carpet weed 5 parts, Rhizoma Ligustici 10 parts, Radix Rhapontici 5 parts, Radix Tripterygii Wilfordii 20 parts, Herba Centipedae 10 parts, Cacumen Securinegae Suffruticosae 15 parts, Rhizoma Corydalis 5 parts.
7. a kind of Chinese medicine composition for the treatment of gastroenteritis according to claim 1, is made up of the crude drug of following weight portion: Herba Euphorbiae Humifusae 25 parts, Folium Perillae 20 parts, Caulis Bambusae In Taenia 15 parts, Herba Artemisiae Scopariae 15 parts, Fructus Evodiae 23 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 14 parts, Folium Psidii Guajavae 13 parts, Herba Portulacae 10 parts, 15 parts, Rhizoma Zingiberis Recens, Cacumen Platycladi 10 parts, Stigma Maydis 10 parts, buckwheat leaf 10 parts, Artemisia eriopoda Bunge. 20 parts, Fructus Bruceae 15 parts, the Radix Pulsatillae 15 parts, carpet weed 10 parts, Rhizoma Ligustici 8 parts, Radix Rhapontici 10 parts, Radix Tripterygii Wilfordii 15 parts, Herba Centipedae 15 parts, Cacumen Securinegae Suffruticosae 10 parts, Rhizoma Corydalis 12 parts.
8. a kind of Chinese medicine composition for the treatment of gastroenteritis described in claim 1-7, is characterized in that, adopts the conventional method of Chinese medicine preparation to be prepared into any traditional oral preparation.
9. a kind of Chinese medicine composition for the treatment of gastroenteritis according to claim 8, is characterized in that, described oral formulations is capsule, pill, powder, tablet, granule, dispersible tablet.
CN201510932333.2A 2015-12-14 2015-12-14 Traditional Chinese medicine composition for curing gastroenteritis Pending CN105396107A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113367247A (en) * 2021-01-05 2021-09-10 安徽科技学院 Feed additive for preventing broiler chicken myogastric and glandular gastritis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142912A (en) * 2013-03-12 2013-06-12 王莉 Traditional Chinese medicine composition for treating chronic gastritis
CN105031488A (en) * 2015-07-02 2015-11-11 张瑜 Traditional Chinese medicinal composition for treating enterogastritis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142912A (en) * 2013-03-12 2013-06-12 王莉 Traditional Chinese medicine composition for treating chronic gastritis
CN105031488A (en) * 2015-07-02 2015-11-11 张瑜 Traditional Chinese medicinal composition for treating enterogastritis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113367247A (en) * 2021-01-05 2021-09-10 安徽科技学院 Feed additive for preventing broiler chicken myogastric and glandular gastritis
CN113367247B (en) * 2021-01-05 2023-11-14 安徽科技学院 Feed additive for preventing stomach proventriculitis of broiler chickens

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Application publication date: 20160316