CN104825612A - Medicine composition for treating gastritis and method for manufacturing medicine composition - Google Patents
Medicine composition for treating gastritis and method for manufacturing medicine composition Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicine, and relates to a medicine composition for treating gastritis. The medicine composition comprises nine medicinal materials including astragalus, concha arcae, radish seeds, radix paeoniae alba, angelica sinensis, rhizoma corydalis, officinal magnolia bark, thin evodia twigs and leaves and licorice. The medicine composition has the advantages that the nine medicinal materials are combined with one another, accordingly, treatment effects can be realized for the gastritis and chronic superficial gastritis in particular, and the total effective rate can reach 95% at least; the medicine composition for treating the gastritis is free of obvious adverse reaction in clinical treatment procedures and accordingly is safe and reliable.
Description
Technical field
The invention belongs to technical field of Chinese medicine, be specifically related to a kind of pharmaceutical composition for the treatment of gastritis and preparation method thereof.
Background technology
Gastritis is the gastric mucosa acute and chronic inflammation that multiple different pathogeny causes, often with epithelial damage, mucosal inflammation reaction and epithelium regeneration.Gastritis is one of modal digestive system disease.
Common clinical manifestation: upper abdominal pain: most of gastritis sufferer has upper abdominal pain.Epigastrium pain majority is irregular, has nothing to do with diet.Pain is generally diffusivity epigastrium causalgia, dull pain, distending pain etc.Abdominal distention: some patients can feel abdominal distention.Usually because gastric retention food, emptying delay, caused by dyspepsia.Belch: have belch.Show that gastric gas increases, discharge through esophagus, make Abdeminal pain respite.Repeated Hemorrhage: hemorrhage is that a kind of gastric mucosa acute inflammation concurrent on gastritis basis changes.. other: inappetence, acid regurgitation, Nausea and vomiting, weak, constipation or diarrhoea etc.
Gastritis belongs to the category such as the traditional Chinese medical science " gastric abscess ", " abdominal distention ", " noisy ", " feeling of fullness ", " syndrome of feeling fullness and distension in the upper abdomen ".Mainly adopt Drug therapy clinically: 1) protect the conventional medicine of gastric mucosa medicine to have colloidal bismuth subcitrate (CBS), sucralfate, Marzulene-S, gel aluminum hydroxide, gastric Mucin etc.2) gastrointestinal motility function medicament Abdeminal pain domperidone etc. is adjusted.Have the hiccups, abdominal distention or have reflux phenomenon to be main person, available medicine for stomach dynamic.3) if antibiotic gastroscopy finds Helicobacter pylori, should antibiotic be taken, clarithromycin, amoxicillin etc., have and remove the effect of Hp, generally can select two kinds, normal and gastric mucosa protective agent and acid inhibitor use in conjunction.4) medicine that antacid is conventional has sodium bicarbonate, magnesium hydroxide, gel aluminum hydroxide etc.5) analgesic Upper abdominal pain is good to eat compared with severe one takes atropine, probanthine, Semen daturae tablet or 654-2, to reduce gastric acid secretion and to alleviate colic symptoms.6) other symptomatic treatment medicines can use digestant, as pancreatin, yeast tablet, lactasinum, simethicone sheet etc.Also can with acid suppression medicine as cimetidine, ranitidine, famotidine etc. if any acid regurgitation phenomenon.Prevent bile reflux from can take hydrotalcite, cholestyramine to adsorb gallbladder juice; Have the hematemesis person of having blood in stool, cimetidine is oral.Visible western medicine is current common method clinically, and right Western medicine needs Long term combined medication could effectively mostly, often causes recurrent exerbation because the interruption of patient is taken medicine, is difficult to obtain desirable therapeutic effect.The treating both the principal and secondary aspects of a disease effect for the treatment of gastritis with Chinese medicine is liked by China's traditional Chinese medical science deeply, is China's traditional Chinese medical science common medicine, but the Chinese medicine for the treatment of at present gastritis is on the market relatively less, alternative few, therefore develops a kind of Chinese medicine for the treatment of gastritis and have huge market prospect.
Summary of the invention
For overcoming the deficiency that medicine of the prior art lacks, the object of this invention is to provide a kind of cure rate high, controlling the pharmaceutical composition of the extremely low treatment gastritis of recurrence rate after healing.
For achieving the above object, the pharmaceutical composition for the treatment of gastritis provided by the invention, is prepared from by the raw material of following weight portion: Radix Astragali 60-300 part, Concha Arcae 60-300 part, Semen Raphani 60-300 part, Radix Paeoniae Alba 30-120 part, Radix Angelicae Sinensis 30-120 part, Rhizoma Corydalis 30-120 part, Cortex Magnoliae Officinalis 30-120 part, Foliumet Ramulus Evodiae 50-200 part, Radix Glycyrrhizae 30-200 part.
One of preferably, the pharmaceutical composition for the treatment of gastritis of the present invention, is prepared from by the raw material of following weight portion: the Radix Astragali 240 parts, Concha Arcae 200 parts, Semen Raphani 200 parts, the Radix Paeoniae Alba 60 parts, Radix Angelicae Sinensis 100 parts, Rhizoma Corydalis 100 parts, Cortex Magnoliae Officinalis 50 parts, Foliumet Ramulus Evodiae 100 parts, 80 parts, Radix Glycyrrhizae.
Preferably two, the pharmaceutical composition for the treatment of gastritis of the present invention, is prepared from by the raw material of following weight portion: the Radix Astragali 300 parts, Concha Arcae 100 parts, Semen Raphani 100 parts, the Radix Paeoniae Alba 100 parts, Radix Angelicae Sinensis 60 parts, Rhizoma Corydalis 120 parts, Cortex Magnoliae Officinalis 100 parts, Foliumet Ramulus Evodiae 200 parts, 60 parts, Radix Glycyrrhizae.
Preferably three, the pharmaceutical composition for the treatment of gastritis of the present invention, is prepared from by the raw material of following weight portion: the Radix Astragali 120 parts, Concha Arcae 240 parts, Semen Raphani 180 parts, the Radix Paeoniae Alba 40 parts, Radix Angelicae Sinensis 40 parts, Rhizoma Corydalis 30 parts, Cortex Magnoliae Officinalis 30 parts, Foliumet Ramulus Evodiae 50 parts, 100 parts, Radix Glycyrrhizae.
The Chinese medicine for the treatment of gastritis of the present invention, its granule is prepared from by the following method:
Take medical material by prescription amount, extracting in water twice, first time adds and is equivalent to medical material gross weight 6-12 water doubly, extracts 2 hours, and second time adds and is equivalent to medical material gross weight 6-8 water doubly, extracts 2 hours; Merge extractive liquid, when being concentrated into 80 DEG C, relative density is the extractum of 1.25, adding ethanol to the concentration of volume percent of alcohol content is 70%, stir even, leave standstill 12-24 hour, filter, when filtrate is concentrated into 80 DEG C, relative density is the extractum of 1.25, obtain described active component, add pharmaceutically acceptable carrier, be prepared into granule.
Preferably, the Chinese medicine for the treatment of gastritis of the present invention, its capsule is prepared from by the following method: take medical material by prescription amount, clean, and dries, mix homogeneously, pulverizes, and cross 80 order-l20 mesh sieves, sterilizing, incapsulates, and to obtain final product.
The pharmacological activity of the present invention's Chinese crude drug used is as follows:
The Radix Astragali: this product is leguminous plant Radix Astagali Astragalus membranaceus(Fisch.) Bge. var. mongholicus(Bge.) Hsiao or Radix Astragali Astragalus membranaceus(Fisch.) dry root of Bge..Spring, Qiu Erji excavate, and removing fibrous root and root head, dry.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Concha Arcae: this product is the shell of Carnis Arca inflata section animal Scapharca subcrenata Arca subcrenata Lischke, Tegillarca granosa Arca granosa Linnaeus or Scapharca broughtonii Arca inflata Reeve.Autumn, spring next year in Winter Solstice fish for, and clean, put in boiling water and slightly boil, fleshing, dry.[nature and flavor] are salty, flat.[return through] returns lung, stomach, Liver Channel.[function cures mainly] expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.For the long-pending knot of pertinacious phlegm, sticky difficulty is coughed up, goiter, scrofula, lump in the abdomen mass in the abdomen, stomachache pantothenic acid.
Semen Raphani: this product is the dry mature seed of crucifer Radix Raphani Raphanus sativus L..Tap plant during fruit maturation in summer, dry, rub seed, removing impurity, then dry.[nature and flavor] are pungent, sweet, flat.[return through] returns lung, spleen, stomach warp.[function cures mainly] helps digestion de-swelling, lowering the adverse-rising QI to resolve phlegm.For retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant heap soil or fertilizer over and around the roots is breathed with cough.
The Radix Paeoniae Alba: this product is the dry root of ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Summer, Qiu Erji excavate, and clean, and remove end to end and radicula, put in boiling water after boiling rear removing crust or peeling and boil, dry.[nature and flavor] are bitter, sour, are slightly cold.[return through] returns liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Radix Angelicae Sinensis: this product is the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Autumn end excavates, and removing fibrous root and silt, after moisture slightly evaporates, be bundled into wisp, upper canopy, with pyrotechnics slowly smoke-dried beancurd.[nature and flavor] sweet, acrid, warm.[return through] returns liver, the heart, spleen channel.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Rhizoma Corydalis: this product is irregular oblate spheroid, diameter 0.5-1.5cm.Surface yellow or yellowish-brown, have irregular netted wrinkle.There is the stem trace of slightly depression on top, and bottom often has pimple shape protruding.Matter is hard and crisp, and section is yellow, and cutin sample, has wax sample gloss.Feeble QI, bitter in the mouth.[nature and flavor] are pungent, bitter, temperature.[return through] returns liver, spleen channel.[function cures mainly] invigorates blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Cortex Magnoliae Officinalis: this product is the dry dried bark of Magnoliacea plant Cortex Magnoliae Officinalis Magnolia officinalis Rehd. et Wils. or magnolia officinalis rehd.et wils.var.biloba rehd.et wils. Magnolia officinalis Rehd. et Wils. var. biloba Rehd. et Wils., root bark and branch skin.The 4-6 month strips, root bark and branch skin Directly Dried in Shadow; Dried bark put in boiling water micro-boil after, dark and damp place of banking up, when " diaphoresis " is to inner surface purpling brown or sepia, steams soft, takes out, is rolled into tubular, dry.[nature and flavor] are bitter, pungent, temperature.[return through] returns spleen, stomach, lung, large intestine channel.The expectorant of [function cures mainly] dampness, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.
Foliumet Ramulus Evodiae: this product is Rutaceae Evodia plant Foliumet Ramulus Evodiae Evodia lepta (Spreng.) Merr., is used as medicine with root and leaf.The whole year can adopt, and root is cleaned, and section is dried for subsequent use; Leaf dries in the shade for subsequent use.[nature and flavor] are bitter, cold.[function cures mainly] heat-clearing and toxic substances removing, eliminating stasis to stop pain.Prevent and treat influenza, epidemic cerebrospinal meningitis, encephalitis B, heatstroke, cure cold high heat, tonsillitis, pharyngolaryngitis, lung abscess, pneumonia, malaria, rheumatic arthritis, sciatica, lumbago and skelalgia, stomachache, icterohepatitis, Gelsemium elegans Benth. (Herba Gelsemii Elegantis) is poisoning.Osteopatia sprain is controlled in external, worm venom, carbuncle furuncle and phyma poison, trauma infection contamination, eczema, dermatitis.
Radix Glycyrrhizae: this product is the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch, Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..Spring, Qiu Erji excavate, and removing fibrous root, dries.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Above 9 taste medical material 5 use, to gastritis, especially chronic superficial gastritis has preferably therapeutical effect, can reach more than 95% through clinical experiment checking total effective rate.And have no obvious adverse reaction clinical treating in process, safe and reliable.And cure patient, follow up a case by regular visits to half a year and have no 1 example recurrence.
Detailed description of the invention
Embodiment 1
Prescription: Radix Astragali 120g, Concha Arcae 240g, Semen Raphani 180g, Radix Paeoniae Alba 40g, Radix Angelicae Sinensis 40g, Rhizoma Corydalis 30g, Cortex Magnoliae Officinalis 30g, Foliumet Ramulus Evodiae 50g, Radix Glycyrrhizae 100g.
Preparation method:
Get above 9 taste medical materials, extracting in water twice, first time adds the water being equivalent to medical material gross weight 10 times, extracts 2 hours, and second time adds the water being equivalent to medical material gross weight 8 times, extracts 2 hours; Merge extractive liquid, when being concentrated into 80 DEG C, relative density is the extractum of 1.25, adding ethanol to the concentration of volume percent of alcohol content is 70%, stir even, leave standstill 12 hours, filter, when filtrate is concentrated into 80 DEG C, relative density is the extractum of 1.25, obtain described active component, add pharmaceutically acceptable carrier, be prepared into granule.
Embodiment 2
Prescription: Radix Astragali 300g, Concha Arcae 100g, Semen Raphani 100g, Radix Paeoniae Alba 100g, Radix Angelicae Sinensis 60g, Rhizoma Corydalis 120g, Cortex Magnoliae Officinalis 100g, Foliumet Ramulus Evodiae 200g, Radix Glycyrrhizae 60g.
Preparation method:
Get above 9 taste medical materials, extracting in water twice, first time adds the water being equivalent to medical material gross weight 12 times, extracts 2 hours, and second time adds the water being equivalent to medical material gross weight 6 times, extracts 2 hours; Merge extractive liquid, when being concentrated into 80 DEG C, relative density is the extractum of 1.25, adding ethanol to the concentration of volume percent of alcohol content is 70%, stir even, leave standstill 12 hours, filter, when filtrate is concentrated into 80 DEG C, relative density is the extractum of 1.25, obtain described active component, add pharmaceutically acceptable carrier, be prepared into granule.
Embodiment 3
Prescription: Radix Astragali 240g, Concha Arcae 200g, Semen Raphani 200g, Radix Paeoniae Alba 60g, Radix Angelicae Sinensis 100g, Rhizoma Corydalis 100g, Cortex Magnoliae Officinalis 50g, Foliumet Ramulus Evodiae 100g, Radix Glycyrrhizae 80g.
Preparation method:
Get above 9 taste medical materials, extracting in water twice, first time adds the water being equivalent to medical material gross weight 8 times, extracts 2 hours, and second time adds the water being equivalent to medical material gross weight 6 times, extracts 2 hours; Merge extractive liquid, when being concentrated into 80 DEG C, relative density is the extractum of 1.25, adding ethanol to the concentration of volume percent of alcohol content is 70%, stir even, leave standstill 24 hours, filter, when filtrate is concentrated into 80 DEG C, relative density is the extractum of 1.25, obtain described active component, add pharmaceutically acceptable carrier, be prepared into granule.
Embodiment 4
Prescription: Radix Astragali 120g, Concha Arcae 240g, Semen Raphani 180g, Radix Paeoniae Alba 40g, Radix Angelicae Sinensis 40g, Rhizoma Corydalis 30g, Cortex Magnoliae Officinalis 30g, Foliumet Ramulus Evodiae 50g, Radix Glycyrrhizae 100g.
Preparation method:
Get above 9 taste medical materials, clean, dry, mix homogeneously, pulverize, cross 80 mesh sieves, sterilizing, incapsulates, and obtains capsule.
Embodiment 5
Prescription: Radix Astragali 300g, Concha Arcae 100g, Semen Raphani 100g, Radix Paeoniae Alba 100g, Radix Angelicae Sinensis 60g, Rhizoma Corydalis 120g, Cortex Magnoliae Officinalis 100g, Foliumet Ramulus Evodiae 200g, Radix Glycyrrhizae 60g.
Preparation method:
Get above 9 taste medical materials, clean, dry, mix homogeneously, pulverize, cross 100 mesh sieves, sterilizing, incapsulates, and obtains capsule.
Embodiment 6
Prescription: Radix Astragali 240g, Concha Arcae 200g, Semen Raphani 200g, Radix Paeoniae Alba 60g, Radix Angelicae Sinensis 100g, Rhizoma Corydalis 100g, Cortex Magnoliae Officinalis 50g, Foliumet Ramulus Evodiae 100g, Radix Glycyrrhizae 80g.
Preparation method:
Get above 9 taste medical materials, clean, dry, mix homogeneously, pulverize, cross 100 mesh sieves, sterilizing, incapsulates, and obtains capsule.
clinical experimental data
1. physical data and diagnosis inclusive criteria
1.1 physical data
Select my institute's internal clinic and chronic superficial gastritis patient 200 example of inpatient's treatment in year April in January, 2013 to 2015, be divided into 2 groups at random, treatment group 100 example, matched group 100 example.
Wherein male 59 example in treatment group, women 41 example, the oldest person 58 years old, minimum 23 years old, average 39.1 years old; The course of disease 1 month-6 years, average 2.4 years.Male 60 example in matched group, women 40 example; The oldest 59 years old, minimum 23 years old, average 39.6 years old, the course of disease 1 month-6 years, average 2.3 years.
Two groups of case sexes, age, symptom and courses of disease etc. compare there was no significant difference, have comparability (P > 0.05).
1.2 diagnostic criterias and case inclusive criteria
Selected case meets " new Chinese medicine guideline of clinical investigations " and " Chinese Internal Medicine " relevant statement, and all cases is all made a definite diagnosis through gastroscope and pathological biopsy, and diagnostic point is as follows:
1) primary symptom is gastralgia, abdominal distention poor appetite, and stool is not smooth, and tongue is red, yellow and greasy fur, and lack of appetite is indigestion and loss of appetite;
2) secondary disease is recurred or increases the weight of for meeting angry or nervous (emotional factors impact), acid regurgitation belch, and feel sick, mouth is sticky;
3) erosion of mucosa congestion and edema and petechia is seen under mirror;
4) see in glandular epithelium in biopsy specimen and occur cell infiltration.
Inclusive criteria:
1) the 18-65 year patient of above-mentioned doctor trained in Western medicine chronic superficial gastritis diagnostic criteria is met;
2) the Syndrome Differentiation of Chinese Medicine disease person that belongs to syndrome of dampness-heat of spleen and stomach;
3) voluntarily and can coordinate participation experimenter.
Exclusion standard
1) chronic atrophic gastritis, esophagus, taste-blindness rate, tumor, the digestive tract organic disease persons such as liver, gallbladder, pancreas;
2) severe cardiac, brain, lung, kidney and hemopoietic system disease patient is suffered from;
3) diabetics;
4) age is less than 18 years old and is greater than 65 years old person;
5) allergic constitution and those who are allergic to this drug;
6) gestation or women breast-feeding their children;
7) psychotic and can not coordinate check patient;
8) not by regulation medication or data is not congruent affects the treatment and safety judgement person.
2. Therapeutic Method
Treatment group: give capsule prepared by the embodiment of the present invention 6, every day 3 times (morning rises, lunch, and before before sleeping, half an hour takes), each 4.
Matched group: give SANJIU WEITAI KELI (Foliumet Ramulus Evodiae, Folium Et Cacumen Murrayae, Radix Zanthoxyli, the Radix Aucklandiae, Radix Scutellariae, Poria, Radix Rehmanniae, the Radix Paeoniae Alba), each 1 bag, every day 2 times, half an hour, warm water was taken after mixing it with water after meal.
Take medicine all continuously 1 month for two groups.
3. disease observation of curative effect and curative effect determinate standard
Observe gastralgia, abdominal distention poor appetite, the main clinic symptoms such as defecate not smooth, according to conditions of patients degree, point without, gently, in, severe, remember 0,2,4,6 point respectively;
Observe acid regurgitation belch, feel sick, the clinical minor symptoms such as mouth is sticky, emotional factors impact, according to conditions of patients degree, point without, light, in, severe, remember 0,1,2,3 point respectively;
Picture of the tongue and pulse condition only as a reference, do not participate in integral and calculating; Cardinal symptom and minor symptom integration add up to total mark; The state of an illness is heavier, marks higher.
Curative effect determinate standard:
Cure: symptom, sign disappear or substantially disappear, disease integration reduces >=95%;
Effective: symptom, sign are obviously improved, disease integration reduces >=70% and < 95%;
Effective: symptom, sign all take a favorable turn, disease integration reduces >=30% and < 70%;
Invalid: symptom, sign all take a favorable turn, disease integration reduces less than 30%.
Disease integral formulas following (nimodipine method):
4. statistical procedures
Data acquisition SPSS18.0 statistical software analyzes.
5. results and analysis
5.1 liang of group curative effects, see table 1.
Table 1. liang group clinical efficacy
Compare with matched group
*p < 0.05.
Table 1 clinical trial results shows, and treatment group cure rate effectively all far above matched group, all has significant difference with total compared with matched group.All obvious adverse reaction is there is not in two groups of therapeutic processes.Cure patient to two groups and all follow up a case by regular visits to half a year, treatment group cures 40 examples, and no case was recurrence.11 examples that matched group is cured, recurrence 3 example.Visible, pharmaceutical composition of the present invention has the effect for the treatment of both the principal and secondary aspects of a disease, can be used as the drug use for the treatment of chronic superficial gastritis.
Claims (8)
1. treat a pharmaceutical composition for gastritis, it is characterized in that being prepared from by the raw material of following weight portion: Radix Astragali 60-300 part, Concha Arcae 60-300 part, Semen Raphani 60-300 part, Radix Paeoniae Alba 30-120 part, Radix Angelicae Sinensis 30-120 part, Rhizoma Corydalis 30-120 part, Cortex Magnoliae Officinalis 30-120 part, Foliumet Ramulus Evodiae 50-200 part, Radix Glycyrrhizae 30-200 part.
2. the pharmaceutical composition for the treatment of gastritis according to claim 1, is characterized in that being prepared from by the raw material of following weight portion: the Radix Astragali 240 parts, Concha Arcae 200 parts, Semen Raphani 200 parts, the Radix Paeoniae Alba 60 parts, Radix Angelicae Sinensis 100 parts, Rhizoma Corydalis 100 parts, Cortex Magnoliae Officinalis 50 parts, Foliumet Ramulus Evodiae 100 parts, 80 parts, Radix Glycyrrhizae.
3. the pharmaceutical composition for the treatment of gastritis according to claim 1, is characterized in that being prepared from by the raw material of following weight portion: the Radix Astragali 300 parts, Concha Arcae 100 parts, Semen Raphani 100 parts, the Radix Paeoniae Alba 100 parts, Radix Angelicae Sinensis 60 parts, Rhizoma Corydalis 120 parts, Cortex Magnoliae Officinalis 100 parts, Foliumet Ramulus Evodiae 200 parts, 60 parts, Radix Glycyrrhizae.
4. the pharmaceutical composition for the treatment of gastritis according to claim 1, is characterized in that being prepared from by the raw material of following weight portion: the Radix Astragali 120 parts, Concha Arcae 240 parts, Semen Raphani 180 parts, the Radix Paeoniae Alba 40 parts, Radix Angelicae Sinensis 40 parts, Rhizoma Corydalis 30 parts, Cortex Magnoliae Officinalis 30 parts, Foliumet Ramulus Evodiae 50 parts, 100 parts, Radix Glycyrrhizae.
5., according to the pharmaceutical composition of the arbitrary described treatment gastritis of claim 1-4, it is characterized in that: described compositions is granule or capsule.
6. the pharmaceutical composition for the treatment of gastritis according to claim 5, it is characterized in that: described granule is prepared from by the following method: take medical material by prescription amount, extracting in water twice, first time adds and is equivalent to medical material gross weight 6-12 water doubly, extract 2 hours, second time adds and is equivalent to medical material gross weight 6-8 water doubly, extracts 2 hours; Merge extractive liquid, when being concentrated into 80 DEG C, relative density is the extractum of 1.25, adding ethanol to the concentration of volume percent of alcohol content is 70%, stir even, leave standstill 12-24 hour, filter, when filtrate is concentrated into 80 DEG C, relative density is the extractum of 1.25, obtain described active component, add pharmaceutically acceptable carrier, be prepared into granule.
7. the pharmaceutical composition for the treatment of gastritis according to claim 5, is characterized in that: described capsule is prepared from by the following method: take medical material by prescription amount, clean, and dries, mix homogeneously, pulverizes, and crosses 80 order-l20 mesh sieves, sterilizing, incapsulates, and to obtain final product.
8. the pharmaceutical composition of the treatment gastritis as described in as arbitrary in claim 1-4, is characterized in that: described gastritis is chronic superficial gastritis.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105213931A (en) * | 2015-09-22 | 2016-01-06 | 崇州市地龙海龙生物制品开发研究所 | A kind of preparation method curing gastritis preparation |
| CN105435074A (en) * | 2015-12-24 | 2016-03-30 | 刘树芹 | Pharmaceutical composition for treating gastritis and application of pharmaceutical composition |
| CN106344606A (en) * | 2016-11-01 | 2017-01-25 | 侯建生 | Medical applications and administration route for ozonized oil |
| CN109432273A (en) * | 2018-11-21 | 2019-03-08 | 熊明彬 | A kind of Chinese medicinal formulae for treating chronic superficial gastritis |
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| CN105213931A (en) * | 2015-09-22 | 2016-01-06 | 崇州市地龙海龙生物制品开发研究所 | A kind of preparation method curing gastritis preparation |
| CN105435074A (en) * | 2015-12-24 | 2016-03-30 | 刘树芹 | Pharmaceutical composition for treating gastritis and application of pharmaceutical composition |
| CN106344606A (en) * | 2016-11-01 | 2017-01-25 | 侯建生 | Medical applications and administration route for ozonized oil |
| CN109432273A (en) * | 2018-11-21 | 2019-03-08 | 熊明彬 | A kind of Chinese medicinal formulae for treating chronic superficial gastritis |
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