CN104524228A - Traditional Chinese medicine for treating arrhythmia due to heart-spleen deficiency and preparation method thereof - Google Patents
Traditional Chinese medicine for treating arrhythmia due to heart-spleen deficiency and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine for treating arrhythmia due to heart-spleen deficiency and a preparation method thereof. The traditional Chinese medicine for treating the arrhythmia due to heart-spleen deficiency is prepared from the following raw materials: stropanthus divericatus, lycoris, coriaceous knotweed rhizome, celery, wilson begonia rhizome, fragrant sarcococca herb, sambucus adnata wall, mimosa pudica, corallodiscus flabellate, cinnabar, hairyvein agrimony, grass, orchidaceae ludisia, dioscorea pentaphylla, companumoea root, panicled fameflower root, dillseed, madder root and humulus lupulus. The traditional Chinese medicine for treating the arrhythmia due to heart-spleen deficiency has the beneficial effects that the theory of traditional Chinese medicines is utilized, and the advantages of quick effect, definite therapeutic effect, high safety, no toxic or side effect and difficulty in recurrence can be realized when the traditional Chinese medicine provided by the invention is used for treating the arrhythmia due to heart-spleen deficiency.
Description
Technical field
The present invention relates to pharmaceutical technology, particularly relate to one and treat the ARR Chinese medicine of type of deficiency of both the heart and spleen and preparation method.
Background technology
Arrhythmia is the change of the origin of heartbeat or the heart beat rhythm caused by conduction abnormalities or frequency, is one of clinical modal Cardiovasculai appearance in patient.The clinical features of patients with arrhythmia differs, and the lighter can without any discomfort, and be occasionally found in time having a medical check-up, serious can jeopardize patient vitals.Patient often showed nervous, breathe hard, uncomfortable in chest, dizziness headache, tinnitus, the symptom such as forgetful, weak.
Arrhythmia is disease comparatively common clinically, and arrhythmia is generally divided into Quick-type to ease up slow type two kinds by doctor trained in Western medicine.Most of antiarrhythmic Western medicine medicine acts on tachyarrhythmia, the medicine of slow arrhythmia then seems comparatively single, and most of antiarrhythmic drug inherently may cause drug resistance, the rhythm of the heart partially slow and there is ARR risk, unsustainablely to take; And artificial pacemaker implantation's treatment, expensive, and not all patient can bear.Therefore, explore other approach treatment arrhythmia and seem significant.
The traditional Chinese medical science has long history, have accumulated abundant diagnosis and treatment experience over the past thousands of years, compared with doctor trained in Western medicine, has novel viewpoint, unique treatment method and definite curative effect to numerous disease.Traditional Chinese medical science more holistic idea, mutual relation between paying special attention to during diagnosis and treatment according to internal organs, the function balance of each internal organs of comprehensive analysis human body, carry out determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, then typing is usually adopted again to distinguish the method controlled to same disease, thus better can carry out symptomatic treatment for disease, obtain good effect.Arrhythmia is attributed in the traditional Chinese medical science " cardiopalmus " or " palpitation with a distress feeling ", arrhythmia can be divided into again type of deficiency of both the heart and spleen, timidness due to deficiency of the heart type, type of deficiency of both QI and YIN, type of hyperactivity of fire caused by deficiency of YIN, flaccidity of the heart-yang type, diseases caused by retention of fluid to insult cardioid, qi stagnation and blood stasis type and phlegm-fire confusing heart type totally eight types clinically, adopt the different rule for the treatment of for every type.Type of deficiency of both the heart and spleen wherein, general clinical manifestation is: shortness of breath and palpitation, lustreless complexion, fatigue and weakness, dizzy forgetful, sleep disorder, ponder over work with one's mind what for.Lip pale tongue, thready and weak pulse.Syndrome analysis: deficiency of both the heart and spleen, insufficiency of vital energy and blood, blood failing to tonify the heart, therefore make up one's mind and throb with fear; Blood fortune is unable, can not go up honor, therefore cause dizziness, lusterless complexion; The anemia deficiency of vital energy, then fatigue and weakness; Light red tongue, thready and weak pulse, or carefully delay, or knot generation, be deficiency of both the heart and spleen, levying of insufficiency of vital energy and blood.
Summary of the invention
Technical problem to be solved by this invention is, there is provided one to be used for the treatment of the ARR Chinese medicine of type of deficiency of both the heart and spleen and preparation method, this treatment by Chinese herbs type of deficiency of both the heart and spleen arrhythmia has the advantage that rapid-action, determined curative effect, safety are high, have no side effect and not easily recur.
In order to solve the problems of the technologies described above, the invention provides one and treating the ARR Chinese medicine of type of deficiency of both the heart and spleen, wherein, comprising following raw medicinal material: Radix Strophanthi Divaricati, Bulbus Lycoridis Radiatae, Rhizoma Polygoni coriacei, Herba Apii graveolentis, Rhizoma Begoniae Willsonii, Sarcococca ruscifolia Stapf, Herba Sambuci Adnatae, Herba Mimosae Pudicae, Herba Corallodisci Flabellati, Cinnabaris, Herba Agrimoniae, Caulis et Folium Polygalae Tenuifoliae, blood aspidistra, five leaf potatos, Radix Campanumoeae, Radix Talini Paniculati, Fructus anethi, Radix Rubiae and Flos lupuli (Flos Humuli Lupuli).
Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably: Radix Strophanthi Divaricati 30 ~ 40 parts, Bulbus Lycoridis Radiatae 20 ~ 30 parts, Rhizoma Polygoni coriacei 15 ~ 25 parts, Herba Apii graveolentis 10 ~ 20 parts, Rhizoma Begoniae Willsonii 10 ~ 20 parts, Sarcococca ruscifolia Stapf 15 ~ 30 parts, Herba Sambuci Adnatae 10 ~ 20 parts, Herba Mimosae Pudicae 20 ~ 30 parts, Herba Corallodisci Flabellati 10 ~ 20 parts, 25 ~ 35 parts, Cinnabaris, Herba Agrimoniae 20 ~ 30 parts, Caulis et Folium Polygalae Tenuifoliae 5 ~ 15 parts, blood aspidistra 20 ~ 30 parts, five leaf potatos 10 ~ 20 parts, Radix Campanumoeae 10 ~ 25 parts, Radix Talini Paniculati 20 ~ 30 parts, Fructus anethi 5 ~ 15 parts, Radix Rubiae 15 ~ 25 parts and Flos lupuli (Flos Humuli Lupuli) 25 ~ 35 parts.
Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can also be preferably: Radix Strophanthi Divaricati 35 ~ 40 parts, Bulbus Lycoridis Radiatae 25 ~ 30 parts, Rhizoma Polygoni coriacei 15 ~ 20 parts, Herba Apii graveolentis 10 ~ 15 parts, Rhizoma Begoniae Willsonii 15 ~ 20 parts, Sarcococca ruscifolia Stapf 20 ~ 30 parts, Herba Sambuci Adnatae 10 ~ 15 parts, Herba Mimosae Pudicae 25 ~ 30 parts, Herba Corallodisci Flabellati 10 ~ 15 parts, 30 ~ 35 parts, Cinnabaris, Herba Agrimoniae 25 ~ 30 parts, Caulis et Folium Polygalae Tenuifoliae 8 ~ 12 parts, blood aspidistra 20 ~ 25 parts, five leaf potatos 15 ~ 20 parts, Radix Campanumoeae 10 ~ 20 parts, Radix Talini Paniculati 20 ~ 25 parts, Fructus anethi 10 ~ 15 parts, Radix Rubiae 15 ~ 20 parts and Flos lupuli (Flos Humuli Lupuli) 25 ~ 30 parts.
Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material also can be preferably: Radix Strophanthi Divaricati 38 parts, Bulbus Lycoridis Radiatae 26 parts, Rhizoma Polygoni coriacei 19 parts, Herba Apii graveolentis 12 parts, Rhizoma Begoniae Willsonii 18 parts, Sarcococca ruscifolia Stapf 24 parts, Herba Sambuci Adnatae 11 parts, Herba Mimosae Pudicae 27 parts, Herba Corallodisci Flabellati 14 parts, 31 parts, Cinnabaris, Herba Agrimoniae 29 parts, Caulis et Folium Polygalae Tenuifoliae 11 parts, blood aspidistra 21 parts, five leaf potatos 16 parts, Radix Campanumoeae 13 parts, Radix Talini Paniculati 21 parts, Fructus anethi 15 parts, Radix Rubiae 17 parts and Flos lupuli (Flos Humuli Lupuli) 25 parts.
Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably again: Radix Strophanthi Divaricati 36 parts, Bulbus Lycoridis Radiatae 28 parts, Rhizoma Polygoni coriacei 17 parts, Herba Apii graveolentis 13 parts, Rhizoma Begoniae Willsonii 16 parts, Sarcococca ruscifolia Stapf 27 parts, Herba Sambuci Adnatae 13 parts, Herba Mimosae Pudicae 29 parts, Herba Corallodisci Flabellati 12 parts, 33 parts, Cinnabaris, Herba Agrimoniae 26 parts, Caulis et Folium Polygalae Tenuifoliae 9 parts, blood aspidistra 23 parts, five leaf potatos 19 parts, Radix Campanumoeae 16 parts, Radix Talini Paniculati 24 parts, Fructus anethi 13 parts, Radix Rubiae 16 parts and Flos lupuli (Flos Humuli Lupuli) 27 parts.
Wherein, when the dosage form of described Chinese medicine is tablet, its preparation method comprises the following steps:
The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, by the micropowders that second step obtains, add relative to the microcrystalline Cellulose of its quality 0.1 ~ 0.3 times, 0.05 ~ 0.15 times of lactose, the starch of 0.1 ~ 0.3 times, sieve, mix homogeneously, granulate, drying, adds relative to micropowders quality 0.005 ~ 0.05 times of magnesium stearate, granulate, tabletting, makes.
Wherein, when the dosage form of described Chinese medicine is decoction, its preparation method comprises the following steps:
Step one: purple casserole is put in described raw medicinal material mixing, adds clear water, to clear water dipped medical material upper surface 2-5cm, soak 3-10 hour;
Step 2: purple casserole is placed on fire, after intense fire boils, using slow fire instead, to decoct the 30-50 minute dosage to medicinal liquid be slowly 100-300ml, filters, obtain filtrate a, for subsequent use;
Step 3: residue medicinal residues are added clear water again, to clear water dipped medical material upper surface 2-3cm, soaks 3-10 hour;
Step 4: be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 25-35 minute dosage to medicinal liquid be slowly 100-300ml, filters, obtain filtrate b, mixed by filtrate a and filtrate b.
Beneficial effect of the present invention: Chinese medicine of the present invention, utilizes the theory of Chinese medical science that China is traditional, and treatment type of deficiency of both the heart and spleen arrhythmia has the advantage that rapid-action, determined curative effect, safety are high, have no side effect and not easily recur.
Detailed description of the invention
The invention provides one and treat the ARR Chinese medicine of type of deficiency of both the heart and spleen, wherein, comprise following raw medicinal material: Radix Strophanthi Divaricati, Bulbus Lycoridis Radiatae, Rhizoma Polygoni coriacei, Herba Apii graveolentis, Rhizoma Begoniae Willsonii, Sarcococca ruscifolia Stapf, Herba Sambuci Adnatae, Herba Mimosae Pudicae, Herba Corallodisci Flabellati, Cinnabaris, Herba Agrimoniae, Caulis et Folium Polygalae Tenuifoliae, blood aspidistra, five leaf potatos, Radix Campanumoeae, Radix Talini Paniculati, Fructus anethi, Radix Rubiae and Flos lupuli (Flos Humuli Lupuli).
Wherein, the pharmacology of above-mentioned raw materials medical material is as follows:
Radix Strophanthi Divaricati: [another name] Cornu Caprae seu Ovis knob (" book on Chinese herbal medicine asks former "), Radix Morindae Umbellatae, fish pen, Cornu Caprae seu Ovis twists (" south of the Five Ridges gather medicinal herbs record "), Cornu Caprae seu Ovis is turned round, Cornu Caprae seu Ovis Rhizoma Nelumbinis (" will planted by middle traditional Chinese medicines "), Gelsemium elegans Benth. (" register planted by Guangxi medicine "); Cornu Caprae seu Ovis willow (" Guangdong Chinese medicine " II), Li Kou flower (" south mainly contains poisonous plant "), Hubei anemone, Radix Gymnematis Sylvestris, Cyprinus carpio Fructus Canarii albi (" Fujian Chinese herbal medicine ").For root or the stem and leaf of apocynaceae plant Radix Strophanthi Divaricati.The whole year can adopt.Hardship, cold, poisonous.Wind-damp dispelling, the meridian dredging, separates sore, parasite killing.Dispelling the wind and dampness pathogens swells and ache, poliomyelitis sequela, traumatic injury, carbuncle skin ulcer, scabies.[extracts] " Chinese medicine voluminous dictionary "
Bulbus Lycoridis Radiatae: [another name] crow Bulbus Allii, black Bulbus Allii, silver-colored key, DUSUAN, mountain bird poison, nine layers of Bulbus Allii, terrible Bulbus Allii, Bullbus Allii nipponici, small stream Bulbus Allii, dragon's paw toothed burclover, Lycoris radiata, wild Bulbus Allii, bald Bulbus Allii, friend be red, 36 barrels, wall Serpentis is raw.For the bulb of amrallid Bulbus Lycoridis Radiatae or Lycoris.Pungent; Sweet; Temperature; Poisonous.Eliminate the phlegm emetic; Detoxicating and resolving stagnation of pathogens.Main acute throat trouble; Single bilateral tonsillitis; Laryngopharynx swelling and pain; Sputum is jammed; Alimentary toxicosis; Breast abdomen hydrops, malignant boil toxic swelling; Sucutaneous nodule scrofula; Anal fistula; Traumatic injury; Rheumatic arthritis; Stubborn dermatitis; Burn and scald; Venom.[extracts] " China's book on Chinese herbal medicine "
Rhizoma Polygoni coriacei: [another name] Rhizoma Bistortae, chicken feet king, hornet seven (" register planted by Guangxi medicine ").For the rhizome of polygonaceae plant leather leaf knotweed.Autumn excavates, and cleans, and selenium is done." the practical Chinese herbal medicine in Guangxi newly selects ": " puckery micro-hardship, flat, nontoxic." heat clearing away, removing toxic substances, convergence, granulation promoting.Control dysentery, diarrhoea, carbuncle, hemorrhoid, burn.[extracts] " Chinese medicine voluminous dictionary "
Herba Apii graveolentis: [another name] Herba Apii graveolentis (" not Lu "), with blue Caulis et folium cryptotaeniae japonicae (" Chinese Plants illustrated handbook "), Apium graveolens, Pu Qin (" book on Chinese herbal medicine pushes away old "), medicine celery (" illustrated handbook planted by middle traditional Chinese medicines "), wild celery (" Chinese herbal medicine is commonly used in Shanghai ").For the herb of samphire Herba Apii graveolentis.Sweetness and bitterness, cool." book on Chinese herbal medicine brief points ": " enter bright, the JUE YIN meridian of foot sun." calming liver and clearing heat, expelling wind and removing dampness.Control hypertension, dizziness and headache, flushing conjunctival congestion, stranguria with blood, carbuncle." the SHENGCAO property of medicine is standby to be wanted ": " enrich blood, dispel the wind, dry.Apply the disease of washing all wind." [extracts] " Chinese medicine voluminous dictionary "
Rhizoma Begoniae Willsonii: be Begoniaceae Begonia plant net arteries and veins Flos Begoniae Evansianae Begonia wilsoniiGagnep., be used as medicine with rhizome.Autumn excavates root stock.Sweet, bitter, flat.Air making-up and spleen enlivening, nourishes blood, stops blooding.Weak after being ill, cough spitting of blood, dysfunctional uterine hemorrhage, leucorrhea.[extracts] " national Chinese herbal medicine compilation "
Sarcococca ruscifolia Stapf: [another name] Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae), Fructus seu semen pruni szechuanicae, wild fan flower, large emaciation due to emotional upset, Rohdea japonica Roth, featherleaf rodgersflower top.This product is Buxaceae Sarcococca plant fragrance osmanthus Sarcococca ruscifolia Stapf, with root and fruit medicine.Spring and autumn adopts root; The fruit picking of autumn in summer, cleans and dries or using fresh herb.Pungent, bitter, flat.Root: regulating QI to relieve pain, dispelling, collateral-activating.For acute and chronic gastritis, gastric ulcer, rheumatic arthritis, traumatic injury.Really: replenishing blood and nourishing liver.For dizziness, cardiopalmus, visual deterioration.[extracts] " national Chinese herbal medicine compilation "
Herba Sambuci Adnatae: [another name] showy reiolaena root-bark, large blood grass, Cortex torricelliae tiliifoliae, blood vessel grass (" Yunnan Chinese herbal medicine "), severe grass, Ramulus Sambuci Williamsii (" Chinese herbal medicine is commonly used in Tibet "), elm Gu Xingnabu (Tibetan name).For herb and the root of caprifoliaceae plant Red Hill flower.Summer, Qiu Cai, chopping is dried or using fresh herb.Xin Gan, temperature.Dispel the wind, diuretic, dissipating blood stasis, dredging collateral.Control acute and chronic nephritis, rheumatalgia, rubella pruritus, poliomyelitis sequela, sprains, fracture." Kunming conventional medical herbs among the people ": " wind-damp dispelling, enriches blood, and invigorates blood circulation, diuresis." [extracts] " Chinese medicine voluminous dictionary "
Herba Mimosae Pudicae: [another name] Biophytum nanum H. Chuang sp. Nov. Ined.-B. Sensitivum auct. Non (L.) DC., drink and exhale grass, know shy grass, be afraid of ugly grass.This product is the herb of pulse family Mimosa plant Herba Mimosae Pudicae Mimosa pudica L..Xia Qiucai, clean, cutting, dries or using fresh herb.Sweet, puckery, cool.Slightly poisonous.Clearing away heat and promoting diuresis, preventing phlegm from forming and stopping coughing, ataralgesia.For flu, infantile hyperpyrexia, acute conjunctivitis, bronchitis, gastritis, enteritis, urinary system calculus, malaria, neurasthenia; Treating swelling and pain by traumatic injury is controlled in external, sore swollen toxin.[extracts] " national Chinese herbal medicine compilation "
Herba Corallodisci Flabellati: [another name] life pulls, Parmelia saxatilis Ach., rock fingernail, relieving palpitation grass (" Yunnan Chinese herbal medicine "), stone lotus, Herba Hylotelephii Mingjiniani (" choosing of Yunnan Chinese herbal medicine "), Graptopelaum Paraguayense (" Kunming conventional medical herbs among the people ").For the herb of Gesneriaceae Herba Corallodisci Flabellati.Autumn, winter gather." choosing of Yunnan Chinese herbal medicine ": " toil, cold." 1. " Yunnan Chinese herbal medicine ": " promoting blood circulation and detoxication, reducing swelling and alleviating pain.Control menoxenia, also under leucorrhea, cardiopalmus, traumatic injury, knife injury, carbuncle sore, stubborn dermatitis." [extracts] " Chinese medicine voluminous dictionary "
Cinnabaris: [another name] cinnabar, cinnabar.This product is sulfide-based mineral cinnabar race cinnabar, main Containing Sulfur hydrargyrum (HgS).After excavating, choose pure person, with the impurity of Magnet exhaustion iron content, then wash in a pan roguing stone and silt with water.Sweet, be slightly cold; Poisonous.GUIXIN warp.Clear away heart-fire relieving convulsion, removing toxic substances of calming the nerves.For palpitation and being susceptible to fright, insomnia and dreamful sleep, epilepsy is gone mad, infantile convulsion, blurring of vision, aphtha, sore throat, sore swollen toxin.[extracts] " Chinese Pharmacopoeia "
Herba Agrimoniae: [another name] Agrimony, Herba silenes fortunei, Indigofera pseudotinctoria, goldentop fossilia dentis mastodi, HUANGLONG tail, dry foot mattress.This product is the dry aerial parts of rosaceous plant Radix Agrimoniae Agrimonia pilosa Ledeb..Summer, autumn two tap when season, stem and leaf was luxuriant, removing impurity, dry.Bitter, puckery, flat.GUIXIN, Liver Channel.Astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances.For hemoptysis, spit blood, metrostaxis, malaria, dysentery, de-power impairment caused by overstrain, carbuncle sore tumefacting virus, pudendal pruritus leukorrhagia.[extracts] " national Chinese herbal medicine compilation "
Caulis et Folium Polygalae Tenuifoliae: [another name] Herba Ceratophylli Demeersi, blue or green Caulis et Folium Polygalae Tenuifoliae.For the herb of milk wort Roots of Polygala tenuifolia Polygalatenuifolia Willd. and Siberia Radix Polygalae Polygala sibirica L..Pungent; Bitter; Property is put down.The heart; Kidney channel.Eliminate the phlegm; Calm the nerves; Eliminating carbuncle.Main cough with copious phlegm; Fidgets due to deficiency; In terror; Nocturnal emission; Obstruction of qi in the chest and cardialgia; Carbuncle skin infection.[extracts] " China's book on Chinese herbal medicine "
Blood aspidistra: [another name] Herba Ludisiae Discoloris, Phryganeajaponica Ml., very golden grass, heterochromatic blood aspidistra.For the herb of orchid blood aspidistra.Sweet in the mouth; Cool in nature.Nourishing YIN and moistening the lung; Spleen invigorating; Calm the nerves.Main pulmonary tuberculosis spitting of blood; Inappetence; Neurasthenia.[extracts] " China's book on Chinese herbal medicine "
Five leaf potatos: [another name] hair Canis familiaris L. sweet potato, beautiful Herba Cistanches, Radix Aristolochiae Kaempferi, hair ball, straw rain cape bag, Herba Wedeliae Wallichii, bitter OK a karaoke club.For the tuber of Dioscoreaceae plant five leaf Rhizoma Dioscoreae.Sweet; Flat.Reinforcing spleen and kidney; Inducing diuresis and reducing edema.Main board is suffered from a deficiency of the kidney weak; Edema; Have loose bowels; Puerperal is thin and weak; Hypogalactia; Innominate toxic swelling.[extracts] " China's book on Chinese herbal medicine "
Radix Campanumoeae: [another name] milk ginseng, native Lac caprae seu ovis, white Radix Panacis Quinquefolii, to the moon ginseng, wild codonopsis, Herba Spirodelae ginseng, Radix Talini Paniculati, native Radix Adenophorae (Radix Glehniae), hundred zhang of light, native ginseng, Silene tatarinowii Regel-Melandrium tatarinwiii (Regel) Tsui., Radix Ginseng potato, moulds step on fruit, Hai Zige, milk starch root, southern Radix Ginseng, Radix Codonopsis Cardiophyllae, river Radix Ginseng.For the root of Campanulaceae Campanumoea javanica and leopard.Sweet in the mouth; Property is put down.Return spleen; Lung meridian.Invigorating the spleen and benefiting QI; Tonifying the lung and stopping cough; Stimulating milk secretion.Main asthenia internal injury; The deficiency of vital energy is weak; Cardiopalmus; Hyperhidrosis; Diarrhea due to hypofunction of the spleen; Leucorrhea; Breast is rare; Infantile malnutrition; The enuresis; Cough due to deficiency of the lung.[extracts] " China's book on Chinese herbal medicine "
Radix Talini Paniculati: [another name] ginseng grass, native Korean Ginseng, Panax pseudoginseng Wall., Silene tatarinowii Regel-Melandrium tatarinwiii (Regel) Tsui., soil ginseng, purple Radix Ginseng, watt hole head, Radix angelicae morii, reddle ginseng, the ginseng that flies here, watt ginseng, cone flower, Radix Talini Paniculati, Fructus Persicae ginseng, the period of the day from 3 p.m. to 5 p.m. are spent.For the root of portulacaceous plant smoke tree orchid.Sweet; Light; Property is put down.Spleen; Lung; Kidney channel.Qi invigorating and lung moistening; Cough-relieving; Regulating menstruation.Main deficiency of vital energy sesame is tired; Lack of appetite; Have loose bowels; Pulmonary tuberculosis hemoptysis; Dizzy; Hectic fever; Night sweat; Spontaneous perspiration; Menoxenia; Leukorrhagia, paturient's hypogalactia.[extracts] " China's book on Chinese herbal medicine "
Fructus anethi: U.S.-China's (Hou Ningji " medicine spectrum ") time [another name], Fructus anethi green pepper (" book on Chinese herbal medicine covers bamboo fish trap "), Fructus Foeniculi (" detailed outline "), shrivelled kernel Fructus Foeniculi (" book on Chinese herbal medicine justice "), cumin (" Chinese medicinal herbal ").Pungent, temperature.Enter spleen, kidney channel.Warming the spleen kidney, appetizing, cold expelling, circulation of qi promoting, separates ichthyosacrotoxin.Control the dirty vomiting of acute diseases such as cholera and sunstroke, cold type of pain in abdomen, colic of cold type, feeling of fullness is eaten less.[extracts] " Chinese medicine voluminous dictionary "
Radix Rubiae: [another name] Herba Chenopodii Hybridi (" native Su Bencao "), Cortex Ampelopsis Aconitifoliae Radicis (" Further Discourses on the Properties of Things "), Abacopteris penangiana (Hook.) Ching, HUOXUEDAN (" detailed outline is picked up any lost article from the road "), red imperial fibrous root (" Guizhou side's medicine among the people collection "), husky alizarin seedling root (" Henan Chinese medicine handbook "), Herba Ipomoeae Cairicae, Herba azollae imbricatae, Radix Bauhihiae Championii (" medicine will is planted in Jiangsu "), red stalk root, child's fist, Radix grewiae bilobae, to uproot plants after their edible portions have been harvested daughter root (" Shandong Chinese medicine "), Radix Rubiae Yunnanensis dragon (" Zhejiang traditional herbal medicine "), Salvia kiaometiensis Levl.f.pubescens Stib., four directions Arisaema balansae Engl. (" east, Fujian book on Chinese herbal medicine "), red rubia (" Jiangsu medical material will ").For the root and rhizome of Maguireothamnus speciosus Radix Rubiae.Spring, autumn excavate, removing stem Seedling, remove earth and thin fibrous root, dry.General is good with the person's of adopting quality in autumn.Hardship, cold.Enter the heart, Liver Channel.Promoting the circulation of blood is stopped blooding, dredge the meridian passage, eliminating phlegm and stopping cough.Control haematemesis, epistaxis, hematuria, have blood in stool, metrorrhagia, amenorrhea, rheumatic arthralgia, traumatic injury, the stasis of blood is stagnant to swell and ache, jaundice, chronic tracheitis.[extracts] " Chinese medicine voluminous dictionary "
Flos lupuli (Flos Humuli Lupuli): [another name] hops, Flos lupuli (" Chinese Herbal Medicine in Xinjiang handbook "), beer Wa Guli (dimension name).For the female inflorescence of moraceae plants Flos lupuli (Flos Humuli Lupuli).Female inflorescence is plucked, using fresh herb or dry for subsequent use when summer, autumn are spent in full bloom.Bitter in the mouth, slightly cool in nature is nontoxic.Invigorating the stomach and promoting digestion, diuresis is calmed the nerves.Control dyspepsia, abdominal distention, edema, cystitis, pulmonary tuberculosis, insomnia.[extracts] " Chinese medicine voluminous dictionary "
Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably: Radix Strophanthi Divaricati 30 ~ 40 parts, Bulbus Lycoridis Radiatae 20 ~ 30 parts, Rhizoma Polygoni coriacei 15 ~ 25 parts, Herba Apii graveolentis 10 ~ 20 parts, Rhizoma Begoniae Willsonii 10 ~ 20 parts, Sarcococca ruscifolia Stapf 15 ~ 30 parts, Herba Sambuci Adnatae 10 ~ 20 parts, Herba Mimosae Pudicae 20 ~ 30 parts, Herba Corallodisci Flabellati 10 ~ 20 parts, 25 ~ 35 parts, Cinnabaris, Herba Agrimoniae 20 ~ 30 parts, Caulis et Folium Polygalae Tenuifoliae 5 ~ 15 parts, blood aspidistra 20 ~ 30 parts, five leaf potatos 10 ~ 20 parts, Radix Campanumoeae 10 ~ 25 parts, Radix Talini Paniculati 20 ~ 30 parts, Fructus anethi 5 ~ 15 parts, Radix Rubiae 15 ~ 25 parts and Flos lupuli (Flos Humuli Lupuli) 25 ~ 35 parts.
Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can also be preferably: Radix Strophanthi Divaricati 35 ~ 40 parts, Bulbus Lycoridis Radiatae 25 ~ 30 parts, Rhizoma Polygoni coriacei 15 ~ 20 parts, Herba Apii graveolentis 10 ~ 15 parts, Rhizoma Begoniae Willsonii 15 ~ 20 parts, Sarcococca ruscifolia Stapf 20 ~ 30 parts, Herba Sambuci Adnatae 10 ~ 15 parts, Herba Mimosae Pudicae 25 ~ 30 parts, Herba Corallodisci Flabellati 10 ~ 15 parts, 30 ~ 35 parts, Cinnabaris, Herba Agrimoniae 25 ~ 30 parts, Caulis et Folium Polygalae Tenuifoliae 8 ~ 12 parts, blood aspidistra 20 ~ 25 parts, five leaf potatos 15 ~ 20 parts, Radix Campanumoeae 10 ~ 20 parts, Radix Talini Paniculati 20 ~ 25 parts, Fructus anethi 10 ~ 15 parts, Radix Rubiae 15 ~ 20 parts and Flos lupuli (Flos Humuli Lupuli) 25 ~ 30 parts.
Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material also can be preferably: Radix Strophanthi Divaricati 38 parts, Bulbus Lycoridis Radiatae 26 parts, Rhizoma Polygoni coriacei 19 parts, Herba Apii graveolentis 12 parts, Rhizoma Begoniae Willsonii 18 parts, Sarcococca ruscifolia Stapf 24 parts, Herba Sambuci Adnatae 11 parts, Herba Mimosae Pudicae 27 parts, Herba Corallodisci Flabellati 14 parts, 31 parts, Cinnabaris, Herba Agrimoniae 29 parts, Caulis et Folium Polygalae Tenuifoliae 11 parts, blood aspidistra 21 parts, five leaf potatos 16 parts, Radix Campanumoeae 13 parts, Radix Talini Paniculati 21 parts, Fructus anethi 15 parts, Radix Rubiae 17 parts and Flos lupuli (Flos Humuli Lupuli) 25 parts.
Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably again: Radix Strophanthi Divaricati 36 parts, Bulbus Lycoridis Radiatae 28 parts, Rhizoma Polygoni coriacei 17 parts, Herba Apii graveolentis 13 parts, Rhizoma Begoniae Willsonii 16 parts, Sarcococca ruscifolia Stapf 27 parts, Herba Sambuci Adnatae 13 parts, Herba Mimosae Pudicae 29 parts, Herba Corallodisci Flabellati 12 parts, 33 parts, Cinnabaris, Herba Agrimoniae 26 parts, Caulis et Folium Polygalae Tenuifoliae 9 parts, blood aspidistra 23 parts, five leaf potatos 19 parts, Radix Campanumoeae 16 parts, Radix Talini Paniculati 24 parts, Fructus anethi 13 parts, Radix Rubiae 16 parts and Flos lupuli (Flos Humuli Lupuli) 27 parts.
Wherein, when the dosage form of described Chinese medicine is tablet, its preparation method comprises the following steps:
The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, by the micropowders that second step obtains, add relative to the microcrystalline Cellulose of its quality 0.1 ~ 0.3 times, 0.05 ~ 0.15 times of lactose, the starch of 0.1 ~ 0.3 times, sieve, mix homogeneously, granulate, drying, adds relative to micropowders quality 0.005 ~ 0.05 times of magnesium stearate, granulate, tabletting, makes.
Wherein, when the dosage form of described Chinese medicine is decoction, its preparation method comprises the following steps:
Step one: purple casserole is put in described raw medicinal material mixing, adds clear water, to clear water dipped medical material upper surface 2-5cm, soak 3-10 hour;
Step 2: purple casserole is placed on fire, after intense fire boils, using slow fire instead, to decoct the 30-50 minute dosage to medicinal liquid be slowly 100-300ml, filters, obtain filtrate a, for subsequent use;
Step 3: residue medicinal residues are added clear water again, to clear water dipped medical material upper surface 2-3cm, soaks 3-10 hour;
Step 4: be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 25-35 minute dosage to medicinal liquid be slowly 100-300ml, filters, obtain filtrate b, mixed by filtrate a and filtrate b.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1 tablet of the present invention
Get Radix Strophanthi Divaricati 380g, Bulbus Lycoridis Radiatae 260g, Rhizoma Polygoni coriacei 190g, Herba Apii graveolentis 120g, Rhizoma Begoniae Willsonii 180g, Sarcococca ruscifolia Stapf 240g, Herba Sambuci Adnatae 110g, Herba Mimosae Pudicae 270g, Herba Corallodisci Flabellati 140g, Cinnabaris 310g, Herba Agrimoniae 290g, Caulis et Folium Polygalae Tenuifoliae 110g, blood aspidistra 210g, five leaf potato 160g, Radix Campanumoeae 130g, Radix Talini Paniculati 210g, Fructus anethi 150g, Radix Rubiae 170g and Flos lupuli (Flos Humuli Lupuli) 250g.
Its preparation method comprises the following steps:
The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 4 times is the ethanol of 95%, reflux 2 hours, extracts, and filters acquisition first extracting solution; It is the ethanol of 85% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 times again, reflux 1 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 2 hours, pulverize, sieve, obtain 300 object micropowders;
3rd step, by the micropowders that second step obtains, adds relative to the microcrystalline Cellulose of its quality 0.24 times, 0.11 times of lactose, the starch of 0.27 times, sieves, mix homogeneously, granulates, dry, adds relative to micropowders quality 0.039 times of magnesium stearate, granulate, tabletting, makes.
Embodiment 2 decoction of the present invention
Get Radix Strophanthi Divaricati 36g, Bulbus Lycoridis Radiatae 28g, Rhizoma Polygoni coriacei 17g, Herba Apii graveolentis 13g, Rhizoma Begoniae Willsonii 16g, Sarcococca ruscifolia Stapf 27g, Herba Sambuci Adnatae 13g, Herba Mimosae Pudicae 29g, Herba Corallodisci Flabellati 12g, Cinnabaris 33g, Herba Agrimoniae 26g, Caulis et Folium Polygalae Tenuifoliae 9g, blood aspidistra 23g, five leaf potato 19g, Radix Campanumoeae 16g, Radix Talini Paniculati 24g, Fructus anethi 13g, Radix Rubiae 16g and Flos lupuli (Flos Humuli Lupuli) 27g.
Its preparation method comprises the following steps:
Step one: purple casserole is put in described raw medicinal material mixing, adds clear water, to clear water dipped medical material upper surface 5cm, soak 5 hours;
Step 2: purple casserole is placed on fire, after intense fire boils, using slow fire instead, to decoct the 40 minutes dosage to medicinal liquid be slowly 200ml, filters, obtain filtrate a, for subsequent use;
Step 3: residue medicinal residues are added clear water again, to clear water dipped medical material upper surface 3cm, soaks 7 hours;
Step 4: be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 35 minutes dosage to medicinal liquid be slowly 300ml, filters, obtain filtrate b, mixed by filtrate a and filtrate b.
Toxicity test:
Acute toxicity test: the tablet dissolved prepared with the embodiment of the present invention 1, in distilled water, is given white mice feeding dispensing with 170 of clinical consumption per day times, observed 14; The all white mice of result are strong deposits, and its activity, diet, hair, Excreta are no abnormal, have no toxic reaction.Irritation test is carried out to white mouse oral cavity and damaged skin, there are no irritative response and other untoward reaction.Illustrate that Chinese medicine of the present invention is little to white mice acute use toxicity, application safety.
Long term toxicity test: the tablet embodiment of the present invention 1 prepared is dissolved in water to mice by 19.27g crude drug/kg, the decoction of the embodiment of the present invention 2 is dissolved in water to mice by 35.48g crude drug/kg, continuous uses 16 weeks are distinguished to 2 groups of mices, every day 2 times, and drug withdrawal is after 4 weeks, result shows: Chinese medicine of the present invention is to the hair of 2 groups of test mices, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, the indexs such as blood fat all have no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 16 weeks and drug withdrawal are after 4 weeks, Organs of Mice is all without obviously changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.
Clinical data:
Case selection: fetch the 120 routine type of deficiency of both the heart and spleen patients with arrhythmia coming from the court's cardiological patients, male 70 people, female 50 people; 24 ~ 63 years old age.120 routine patients are divided into treatment by Chinese herbs group and western medicine group at random, treatment by Chinese herbs group 60 people, male 30 people, female 30 people; 24 ~ 60 years old age; Western medicine group 60 people, male 36 people, female 24 people; 26 ~ 63 years old age.
Diagnostic criteria: 1, there is typical cardiopalmus symptom; 2, the arrhythmia such as frequent premature beat, paroxysmal tachycardia, rapidity atrial fibrillation are diagnosed as through more than 2 times tranquil electrocardiograms or 24 hr Ambulatory EKG Monitoring inspections; 3,18 ~ 78 years old; 4, Liver and kidney function is normal; And meet the ARR tcm syndrome of type of deficiency of both the heart and spleen: deficiency of both the heart and spleen, insufficiency of vital energy and blood, blood failing to tonify the heart, blood fortune is unable, the anemia deficiency of vital energy etc., having the ARR general clinical manifestation of type of deficiency of both the heart and spleen is: shortness of breath and palpitation, lustreless complexion, fatigue and weakness, dizzy forgetful, sleep disorder, ponder over work with one's mind what for.Lip pale tongue, thready and weak pulse.
Exclusion standard: 1, severe cardiac functional defect; 2, II °, III ° atrioventricular block; 3, sustained ventricular tachycardia, room are flutterred, room quivers; 4, sinus bradycardia; 5, iodine preparation is irritated.
Therapeutic Method:
Treatment by Chinese herbs group: take tablet prepared by the embodiment of the present invention 1, every day 3 times, each 4; It within 4 weeks, is 1 course for the treatment of.
Western medicine group: oral hydrochloride amiodarone, each 0.2g, every day 3 times; Each 0.2g is changed into, every day 2 times after 7 days; Each 0.2g is changed into, every day 1 time after 14 days; It within 4 weeks, is 1 course for the treatment of.
The standard of curative effect evaluation: recovery from illness: clinical symptom disappearance, the premature beat of 24h dynamic ecg monitoring all disappears or reduces more than 75%; Take a turn for the better: premature beat reduces 50% ~ 75%, clinical symptom disappearance or improvement; Invalid: before and after medication unchanged or change less.
Therapeutic outcome:
See table 1 and table 2, as can be seen from Table 1, adopt treatment by Chinese herbs type of deficiency of both the heart and spleen arrhythmia of the present invention, relative to Western medicine on therapeutic effect, there is significant improvement; As can be seen from Table 2, adopt treatment by Chinese herbs type of deficiency of both the heart and spleen arrhythmia of the present invention, relative to Western medicine, treatment the course for the treatment of on significantly shorten.
Table 1 liang group treats Clinical efficacy comparison example (%) after 1 course for the treatment of respectively
| Group | Number of cases | Recovery from illness (%) | Take a turn for the better (%) | Invalid (%) | Total effective rate |
| Treatment group | 60 | 41(68.3％) | 18(30％) | 1(1.7％) | 98.3％ |
| Matched group | 60 | 22(36.7％) | 30(50％) | 8(13.3％) | 86.7％ |
To fully recover after table 2 liang group treats 1 course for the treatment of respectively number and time comparative example (%)
| Group | Number of cases | 1st week | 2nd week | 3rd week | 4th week |
| Treatment group | 41 | 5(12.2％) | 13(31.7％) | 14(34.1％) | 9(21.9％) |
| Matched group | 22 | 0(0％) | 3(13.6％) | 7(31.8％) | 12(54.5％) |
According to the clinical statistics in above table, Chinese medicine provided by the invention have rapid-action, effective percentage is high, determined curative effect, safety are high, the advantage that has no side effect; Simultaneously to 41 examples for the treatment of group recovery from illness and the 22 routine follow-up of patients 1 year of matched group recovery from illness, result is added up, and treatment group 41 example is without recurrence, and the routine patient of matched group 22, recurs 5 people, relapse rate 22.7%.
Model case: Zhao, women, 32 years old, easily wake up because of cardiopalmus and sleep and be admitted to hospital, be diagnosed as arrhythmia, then according to shortness of breath and palpitation through electrocardiogram and 24h ambulatory electrocardiogram etc. inspections, lustreless complexion, fatigue and weakness, dizzy forgetful, sleep disorder, ponder over work with one's mind what for, lip pale tongue, thready and weak pulse, is diagnosed as type of deficiency of both the heart and spleen arrhythmia further.Take the tablet of Chinese medicine preparation embodiment 1 of the present invention, every day 3 times, each 4, treat and be almost recovered for 2 weeks, fully recover after continuing to take 5 days, follow up a case by regular visits to and do not recur for 1 year.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (9)
1. treat the ARR Chinese medicine of type of deficiency of both the heart and spleen, it is characterized in that, comprise following raw medicinal material: Radix Strophanthi Divaricati, Bulbus Lycoridis Radiatae, Rhizoma Polygoni coriacei, Herba Apii graveolentis, Rhizoma Begoniae Willsonii, Sarcococca ruscifolia Stapf, Herba Sambuci Adnatae, Herba Mimosae Pudicae, Herba Corallodisci Flabellati, Cinnabaris, Herba Agrimoniae, Caulis et Folium Polygalae Tenuifoliae, blood aspidistra, five leaf potatos, Radix Campanumoeae, Radix Talini Paniculati, Fructus anethi, Radix Rubiae and Flos lupuli (Flos Humuli Lupuli).
2. Chinese medicine as claimed in claim 1, it is characterized in that, in described Chinese medicine, the ratio of weight and number of each raw medicinal material is: Radix Strophanthi Divaricati 30 ~ 40 parts, Bulbus Lycoridis Radiatae 20 ~ 30 parts, Rhizoma Polygoni coriacei 15 ~ 25 parts, Herba Apii graveolentis 10 ~ 20 parts, Rhizoma Begoniae Willsonii 10 ~ 20 parts, Sarcococca ruscifolia Stapf 15 ~ 30 parts, Herba Sambuci Adnatae 10 ~ 20 parts, Herba Mimosae Pudicae 20 ~ 30 parts, Herba Corallodisci Flabellati 10 ~ 20 parts, 25 ~ 35 parts, Cinnabaris, Herba Agrimoniae 20 ~ 30 parts, Caulis et Folium Polygalae Tenuifoliae 5 ~ 15 parts, blood aspidistra 20 ~ 30 parts, five leaf potatos 10 ~ 20 parts, Radix Campanumoeae 10 ~ 25 parts, Radix Talini Paniculati 20 ~ 30 parts, Fructus anethi 5 ~ 15 parts, Radix Rubiae 15 ~ 25 parts and Flos lupuli (Flos Humuli Lupuli) 25 ~ 35 parts.
3. Chinese medicine as claimed in claim 1 or 2, it is characterized in that, in described Chinese medicine, the ratio of weight and number of each raw medicinal material is: Radix Strophanthi Divaricati 35 ~ 40 parts, Bulbus Lycoridis Radiatae 25 ~ 30 parts, Rhizoma Polygoni coriacei 15 ~ 20 parts, Herba Apii graveolentis 10 ~ 15 parts, Rhizoma Begoniae Willsonii 15 ~ 20 parts, Sarcococca ruscifolia Stapf 20 ~ 30 parts, Herba Sambuci Adnatae 10 ~ 15 parts, Herba Mimosae Pudicae 25 ~ 30 parts, Herba Corallodisci Flabellati 10 ~ 15 parts, 30 ~ 35 parts, Cinnabaris, Herba Agrimoniae 25 ~ 30 parts, Caulis et Folium Polygalae Tenuifoliae 8 ~ 12 parts, blood aspidistra 20 ~ 25 parts, five leaf potatos 15 ~ 20 parts, Radix Campanumoeae 10 ~ 20 parts, Radix Talini Paniculati 20 ~ 25 parts, Fructus anethi 10 ~ 15 parts, Radix Rubiae 15 ~ 20 parts and Flos lupuli (Flos Humuli Lupuli) 25 ~ 30 parts.
4. the Chinese medicine as described in claims 1 to 3, is characterized in that, in described Chinese medicine, the ratio of weight and number of each raw medicinal material is: Radix Strophanthi Divaricati 38 parts, Bulbus Lycoridis Radiatae 26 parts, Rhizoma Polygoni coriacei 19 parts, Herba Apii graveolentis 12 parts, Rhizoma Begoniae Willsonii 18 parts, Sarcococca ruscifolia Stapf 24 parts, Herba Sambuci Adnatae 11 parts, Herba Mimosae Pudicae 27 parts, Herba Corallodisci Flabellati 14 parts, 31 parts, Cinnabaris, Herba Agrimoniae 29 parts, Caulis et Folium Polygalae Tenuifoliae 11 parts, blood aspidistra 21 parts, five leaf potatos 16 parts, Radix Campanumoeae 13 parts, Radix Talini Paniculati 21 parts, Fructus anethi 15 parts, Radix Rubiae 17 parts and Flos lupuli (Flos Humuli Lupuli) 25 parts.
5. the Chinese medicine as described in claims 1 to 3, is characterized in that, in described Chinese medicine, the ratio of weight and number of each raw medicinal material is: Radix Strophanthi Divaricati 36 parts, Bulbus Lycoridis Radiatae 28 parts, Rhizoma Polygoni coriacei 17 parts, Herba Apii graveolentis 13 parts, Rhizoma Begoniae Willsonii 16 parts, Sarcococca ruscifolia Stapf 27 parts, Herba Sambuci Adnatae 13 parts, Herba Mimosae Pudicae 29 parts, Herba Corallodisci Flabellati 12 parts, 33 parts, Cinnabaris, Herba Agrimoniae 26 parts, Caulis et Folium Polygalae Tenuifoliae 9 parts, blood aspidistra 23 parts, five leaf potatos 19 parts, Radix Campanumoeae 16 parts, Radix Talini Paniculati 24 parts, Fructus anethi 13 parts, Radix Rubiae 16 parts and Flos lupuli (Flos Humuli Lupuli) 27 parts.
6. the Chinese medicine as described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is tablet, and its preparation method comprises the following steps:
The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, by the micropowders that second step obtains, add relative to the microcrystalline Cellulose of its quality 0.1 ~ 0.3 times, 0.05 ~ 0.15 times of lactose, the starch of 0.1 ~ 0.3 times, sieve, mix homogeneously, granulate, drying, adds relative to micropowders quality 0.005 ~ 0.05 times of magnesium stearate, granulate, tabletting, makes.
7. the Chinese medicine as described in claim 1 to 5, is characterized in that, when the dosage form of described Chinese medicine is decoction, its preparation method comprises the following steps:
Step one: purple casserole is put in described raw medicinal material mixing, adds clear water, to clear water dipped medical material upper surface 2-5cm, soak 3-10 hour;
Step 2: purple casserole is placed on fire, after intense fire boils, using slow fire instead, to decoct the 30-50 minute dosage to medicinal liquid be slowly 100-300ml, filters, obtain filtrate a, for subsequent use;
Step 3: residue medicinal residues are added clear water again, to clear water dipped medical material upper surface 2-3cm, soaks 3-10 hour;
Step 4: be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 25-35 minute dosage to medicinal liquid be slowly 100-300ml, filters, obtain filtrate b, mixed by filtrate a and filtrate b.
8. a preparation method for Chinese medicine described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is tablet, and its preparation method comprises the following steps:
The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, by the micropowders that second step obtains, add relative to the microcrystalline Cellulose of its quality 0.1 ~ 0.3 times, 0.05 ~ 0.15 times of lactose, the starch of 0.1 ~ 0.3 times, sieve, mix homogeneously, granulate, drying, adds relative to micropowders quality 0.005 ~ 0.05 times of magnesium stearate, granulate, tabletting, makes.
9. the preparation method of Chinese medicine described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is decoction, and its preparation method comprises the following steps:
Step one: purple casserole is put in described raw medicinal material mixing, adds clear water, to clear water dipped medical material upper surface 2-5cm, soak 3-10 hour;
Step 2: purple casserole is placed on fire, after intense fire boils, using slow fire instead, to decoct the 30-50 minute dosage to medicinal liquid be slowly 100-300ml, filters, obtain filtrate a, for subsequent use;
Step 3: residue medicinal residues are added clear water again, to clear water dipped medical material upper surface 2-3cm, soaks 3-10 hour;
Step 4: be placed in by purple casserole on fire, after intense fire boils, using slow fire instead, to decoct the 25-35 minute dosage to medicinal liquid be slowly 100-300ml, filters, obtain filtrate b, mixed by filtrate a and filtrate b.
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| CN104940653A (en) * | 2015-06-11 | 2015-09-30 | 山东新希望六和集团有限公司 | Pharmaceutical composition for treating sunstroke and heatstroke of cattle and preparation method of pharmaceutical composition |
| CN105056159A (en) * | 2015-09-25 | 2015-11-18 | 山东新希望六和集团有限公司 | Medicine for treating parasitic diseases of pigs and preparation method thereof |
| CN105056085A (en) * | 2015-08-06 | 2015-11-18 | 山东新希望六和集团有限公司 | Pharmaceutical composition for treating bovine osteomalacia and preparation method thereof |
| CN105596590A (en) * | 2016-01-12 | 2016-05-25 | 卢磊红 | Traditional Chinese medicine preparation for treating herpes labialis and preparation method thereof |
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| CN101444617A (en) * | 2008-12-19 | 2009-06-03 | 宗翠红 | Traditional Chinese medicine formula for oral administration used for treating arrhythmia |
| CN103100078A (en) * | 2013-03-11 | 2013-05-15 | 兰继民 | Traditional Chinese medicine preparation for treating cardiac arrhythmia |
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| CN101444617A (en) * | 2008-12-19 | 2009-06-03 | 宗翠红 | Traditional Chinese medicine formula for oral administration used for treating arrhythmia |
| CN103100078A (en) * | 2013-03-11 | 2013-05-15 | 兰继民 | Traditional Chinese medicine preparation for treating cardiac arrhythmia |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104940653A (en) * | 2015-06-11 | 2015-09-30 | 山东新希望六和集团有限公司 | Pharmaceutical composition for treating sunstroke and heatstroke of cattle and preparation method of pharmaceutical composition |
| CN105056085A (en) * | 2015-08-06 | 2015-11-18 | 山东新希望六和集团有限公司 | Pharmaceutical composition for treating bovine osteomalacia and preparation method thereof |
| CN105056159A (en) * | 2015-09-25 | 2015-11-18 | 山东新希望六和集团有限公司 | Medicine for treating parasitic diseases of pigs and preparation method thereof |
| CN105596590A (en) * | 2016-01-12 | 2016-05-25 | 卢磊红 | Traditional Chinese medicine preparation for treating herpes labialis and preparation method thereof |
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