CN104740483A - Traditional Chinese medicine used for treating recurrent oral ulceration - Google Patents
Traditional Chinese medicine used for treating recurrent oral ulceration Download PDFInfo
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- CN104740483A CN104740483A CN201510199448.5A CN201510199448A CN104740483A CN 104740483 A CN104740483 A CN 104740483A CN 201510199448 A CN201510199448 A CN 201510199448A CN 104740483 A CN104740483 A CN 104740483A
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Abstract
The invention relates to a traditional Chinese medicine used for treating recurrent oral ulceration. The traditional Chinese medicine is prepared by raw material medicinal materials in the following weight proportions: 15 parts of rhizoma atractylodis, 15 parts of angelica sinensis, 10 parts of magnolia officinalis, 20 parts of honeysuckle, 10 parts of Scutellaria baicalensis, 10 parts of coptis chinensis, 9 parts of cimicifugae foetidae, and 10 parts of alpinia katsumadai. Clinical experiments prove that the traditional Chinese medicine is capable of safely and effectively treating the recurrent oral ulceration.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of recurrent oral ulceration.
Background technology
Oral ulcer, is also called aphtha, is the superficial ulcer occurred on oral mucosa, large I from the grain of rice to Semen Glycines size, circular or oval, ulcer surface is recessed, congested around, and can cause pain because of irritable food, generally one or two week can spontaneous recovery.Oral ulcer inducement may be local wound, psychentonia, food, medicine, hormonal readiness change and vitamin or trace element deficiency.Systemic disease, heredity, immunity and microorganism may play an important role in the generation, development of oral ulcer.
Recurrent oral ulceration refers to the pain of recurrent exerbation and agnogenic ulcer, and sickness rate is high, belongs to motherland's medical science " aphtha ", " aphtha " category.Though the traditional Chinese medical science thinks that primary disease is born in mouth, real closely related with zang-fu differentiation.The mouth is the body opening or window of the spleen for edge, the tongue is the orifice to the heart, and it is tongue basis that the kidney pulse connects pharynx, and two cheeks and gums belong to stomach and large intestine channel.It mostly is surfeit delicious food savoury, or oral cavity is not bought, and feels exopathogen again, fire formation from evil accumulation, and impairment of YIN consumption liquid, sick and heart kidney, cause heart spleen kidney all hot, excess-heat is flourishing, and upper inflammation is fallen ill in oral cavity, and this mostly is excess-fire.Again by the ferritic deficiency of YIN, or obstinate disease, dark consumption is Kidney-Yin, injures heart kidney, deficiency of YIN affecting YANG, causes heart spleen kidney all empty, hyperactivity of deficient fire, and smoked burning in mouth forms disease, and this belongs to asthenic fire more.
Medical material present Research involved in the present invention is as follows:
Rhizoma Atractylodis [another name] red art, Ma Ji, blue or green art, magic arts.[source] this product is the dry rhizome of feverfew Atractylodes lancea (Thunb.) DC. or Atractylis chinensis.Spring, Qiu Erji excavate, and removing silt, dries, hit fibrous root.[nature and flavor] are pungent, bitter, temperature.[return through] returns spleen, stomach, Liver Channel.[function cures mainly] is drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.[usage and dosage] takes orally: decoct soup, 3 ~ 10g.[attention] yin asthenia generating intrinsic heat, deficiency of vital energy hyperhidrosis person avoids clothes.[extracts] " China's book on Chinese herbal medicine ".
Radix Angelicae Sinensis [another name] is dry returns.[source] this product is the dry root of umbelliferae angelica.Autumn end excavates, and removing fibrous root and silt, after moisture slightly evaporates, be bundled into wisp, upper canopy, with pyrotechnics slowly smoke-dried beancurd.[nature and flavor] sweet, acrid, warm.[return through] returns liver, the heart, spleen channel.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.[usage and dosage] takes orally: decoct soup, 10 ~ 25g.[attention] dampness fullness in the epigastrium and abdomen and the careful clothes of diarrhea with loose stool person.[extracts] " China's book on Chinese herbal medicine ".
Cortex Magnoliae Officinalis [another name] Cortex Magnoliae Officinalis, CORTEX MAGNOLIAE OFFICINALIS.[source] this product is the dry dried bark of Magnoliacea plant Cortex Magnoliae Officinalis or magnolia officinalis rehd.et wils.var.biloba rehd.et wils., root bark and branch skin.4 ~ June strips, root bark and branch skin Directly Dried in Shadow; Dried bark put in boiling water micro-boil after, dark and damp place of banking up, when " diaphoresis " is to inner surface purpling brown or sepia, steams soft, takes out, is rolled into tubular, dry.[nature and flavor] are bitter, pungent, temperature.[return through] returns spleen, stomach, lung, large intestine channel.The expectorant of [function cures mainly] dampness, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] anemia of pregnant woman is cautious use of.Rhizoma Zingiberis makes for it.Dislike Rhizoma Alismatis, Mirabilitum crystallina, Sal Nitri.[extracts] " China's book on Chinese herbal medicine ".
Flos Lonicerae [another name] Flos Lonicerae, Flos Lonicerae, little egret flower, Su Hua, JINHUA, golden rattan, Flos Lonicerae, two bud flower, Flos Lonicerae, two precious flowers.[source] this product is caprifoliaceae plant Radix Ophiopogonis, Flos Lonicerae, the Flos Lonicerae (flower that the dry flower of hair calyx Radix Ophiopogonis or hair style Radix Ophiopogonis or band are just opened.Early summer the flowers are in blossom put before gather, dry.[nature and flavor] are sweet, cold.[return through] returns lung, the heart, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[attention] Deficiency and coldness of spleen and stomach and deficiency of vital energy skin infection pus-serum person avoid clothes.[extracts] " China's book on Chinese herbal medicine ".
The Radix Astragali [another name] continuous stilbene, the continuous Radix Astragali.[source] this product is the dry root of leguminous plant Radix Astagali or Radix Astragali.Spring, Qiu Erji excavate, and removing fibrous root and root head, dry.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.[usage and dosage] takes orally: decoct soup, 9 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Coptidis [another name] Rhizoma Coptidis, Jiang Lian, Rhizoma Coptidis.[source] herbaceos perennial, happiness cools, moistening part, belongs to Ranunculaceae Coptis.[nature and flavor] (root) is bitter, cold, nontoxic.[return through] GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.[usage and dosage] takes orally: decoct soup, 2 ~ 5g.[attention] this product large bitter Great Cold, cross clothes and take injuring spleen-stomach for a long time, Deficiency and coldness of spleen and stomach person avoids use.Bitter dry impairment of body fluid, deficiency of YIN Tianjin the wounded is cautious use of.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Cimicifugae [another name] Radix Longan, hole root of the tooth.[source] Chinese medicine Rhizoma Cimicifugae is the rhizome of Ranunculaceae herbaceos perennial SANYE Rhizoma Cimicifugae or Cimicifuga Dahurica or Rhizoma Cimicifugae.[nature and flavor] are pungent, sweet, are slightly cold.[return through] returns lung, spleen, large intestine, stomach warp.[function cures mainly] delivers rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, measles is not smooth, toothache aphtha, laryngopharynx swelling and pain, visceroptosis.[usage and dosage] takes orally: decoct soup, 3 ~ 10g.[attention] yang deficiency sun is floating, and dyspnea with fullness of the chest QI rising in reverse order and measles thoroughly person avoid use.Elevate a turnable ladder yang-energy should with processing Rhizoma Cimicifugae.[extracts] " China's book on Chinese herbal medicine ".
Semen Alpiniae Katsumadai [another name] Amomum globosum loureiro, Semen Alpiniae Katsumadai, false fiber crops tree, even son.[source] this product is the dry near mature seed of zingiberaceous plant Semen Alpiniae Katsumadai.Summer, Qiu Erji gather, and shine to ninety percent dry, or slightly scald with water, shine to half-dried, and removing peel, takes out seed group, dry.[nature and flavor] are pungent, temperature.[return through] returns spleen, stomach warp.[function cures mainly] is drying damp and strengthening spleen, stomach warming preventing or arresting vomiting.For internal retention of cold wetness, distension and fullness in the abdomen cold type of pain, belch vomiting, anorexia.[usage and dosage] takes orally: decoct soup, 3 ~ 12g.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of recurrent oral ulceration, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing recurrent oral ulceration.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of recurrent oral ulceration, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Rhizoma Atractylodis 15 parts, Radix Angelicae Sinensis 15 parts, Cortex Magnoliae Officinalis 10 parts, Flos Lonicerae 20 parts, Radix Scutellariae 10 parts, Rhizoma Coptidis 10 parts, Rhizoma Cimicifugae 9 parts, Semen Alpiniae Katsumadai 10 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and Blood of Patients with Recurrent Oral 60 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 30 example and matched group 30 example at random, treatment group man 19 example, female 11 example; Matched group man 17 example, female 13 example.16 ~ 55 years old age, the course of disease half a year ~ 10 years.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national recurrent oral ulceration clinical speciality: (1) ulcer is rounded or oval, size, number not etc., is not dispersed in distribution, neat in edge, has blush around, and sense pain, has self limiting and recurrent history, do not stay cicatrix more.(2) ulcer is little and number can reach more than 20, and distributed more widely general, without cluster and fusion phenomenon, patient has pain and with headache, the General Symptomies such as low grade fever, do not stay cicatrix more.(3) be apt to occur in inside lip and bicker district mucosa, the how single generation of ulcer, and dark greatly, in " crater " shape, marginal swell, the end, is uneven firmly micro-, and the course of disease is long, can leave cicatrix more.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.10 days courses for the treatment of.
The oral prednisone of matched group (by specification is taken).10 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: pain disappears, ulcer all healed;
Effective: pain obviously alleviates, ulcer area reduces more than 50%;
Effective: pain relief, ulcer area minimizing is less than 50%;
Invalid: pain has no and alleviates, ulcer has no obvious minimizing.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment recurrent oral ulceration, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Rhizoma Atractylodis 15 grams, Radix Angelicae Sinensis 15 grams, Cortex Magnoliae Officinalis 10 grams, Flos Lonicerae 20 grams, Radix Scutellariae 10 grams, Rhizoma Coptidis 10 grams, Rhizoma Cimicifugae 9 grams, Semen Alpiniae Katsumadai 10 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of recurrent oral ulceration.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Rhizoma Atractylodis 15 grams, Radix Angelicae Sinensis 15 grams, Cortex Magnoliae Officinalis 10 grams, Flos Lonicerae 20 grams, Radix Scutellariae 10 grams, Rhizoma Coptidis 10 grams, Rhizoma Cimicifugae 9 grams, Semen Alpiniae Katsumadai 10 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of recurrent oral ulceration.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Rhizoma Atractylodis 15 grams, Radix Angelicae Sinensis 15 grams, Cortex Magnoliae Officinalis 10 grams, Flos Lonicerae 20 grams, Radix Scutellariae 10 grams, Rhizoma Coptidis 10 grams, Rhizoma Cimicifugae 9 grams, Semen Alpiniae Katsumadai 10 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of recurrent oral ulceration.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 4
The present embodiment describes a kind of decocting method being used for the treatment of the Chinese medicine of recurrent oral ulceration, decocts many parts of Chinese medicines by machine for decocting Chinese traditional herb medicines, boils medicine simultaneously, raise the efficiency to the patient mostly being symptom identical.Can use the method in Chinese medicine pharmacy, everyone is corresponding a.Everyone corresponding embodiment 2 of amount.
Wherein, materials decoction device has following function, to improve the drug effect in decoction process: certainly do not have function below, and adopt traditional materials decoction device to be also feasible:
1, in decoction process, the duration and degree of heating is arranged to automatic adjustment, to guarantee drug effect, as adopted existing machine for decocting Chinese traditional herb medicines (ZL201020200404.2);
2, have the step of the heavy metal purification in middle liquid medicine in decoction process, the purifier that picture 201420144514.X " pot for decocting medicinal herbs " adopts can be set in above-mentioned machine for decocting Chinese traditional herb medicines, remove the heavy metal in Chinese traditional medicine water extract;
3, by the function that bulk Chinese medicine shreds, after effectively cutting for Chinese crude drug, add water and carry out heating and boil medicine, as adopted as 201420499746.7 Traditional Chinese medicine decocting devices; Also it can be adopted to determine the scheme of the ratio of adding water by rule, and then boil medicine more easily, improve the environment of Traditional Chinese medicine decocting, improve the quality of boiling medicine, more convenient to use.
4, in machine for decocting Chinese traditional herb medicines, must safety equipment be set, as relief valve, effectively must improve safety in batch decoction process;
5, in machine for decocting Chinese traditional herb medicines, agitating function is added, in decoction process, slight stirring can be carried out to the medical material of inside, agitating function can have been come by double-speed motor and stirring arm, double-speed motor has high and low shift rotating speed, stirring arm can run in the mode of low speed-at a high speed-low speed, and time point ratio is: 5:1:4; Stirring arm does not adopt conventional helical to starch, and adopts the structure (Y shape) in forked.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of recurrent oral ulceration, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Rhizoma Atractylodis 15 parts, Radix Angelicae Sinensis 15 parts, Cortex Magnoliae Officinalis 10 parts, Flos Lonicerae 20 parts, Radix Scutellariae 10 parts, Rhizoma Coptidis 10 parts, Rhizoma Cimicifugae 9 parts, Semen Alpiniae Katsumadai 10 parts.
2. be used for the treatment of the Chinese medicine of recurrent oral ulceration as claimed in claim 1, it is characterized in that, its preparation method is: take: Rhizoma Atractylodis 15 parts, Radix Angelicae Sinensis 15 parts, Cortex Magnoliae Officinalis 10 parts, Flos Lonicerae 20 parts, Radix Scutellariae 10 parts, Rhizoma Coptidis 10 parts, Rhizoma Cimicifugae 9 parts, Semen Alpiniae Katsumadai 10 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. as claimed in claim 1 for treating the Chinese medicine of recurrent oral ulceration, it is characterized in that, its preparation method is: take: Rhizoma Atractylodis 15 parts, Radix Angelicae Sinensis 15 parts, Cortex Magnoliae Officinalis 10 parts, Flos Lonicerae 20 parts, Radix Scutellariae 10 parts, Rhizoma Coptidis 10 parts, Rhizoma Cimicifugae 9 parts, Semen Alpiniae Katsumadai 10 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the Chinese medicine of recurrent oral ulceration as claimed in claim 1, it is characterized in that, its preparation method is: take: Rhizoma Atractylodis 15 parts, Radix Angelicae Sinensis 15 parts, Cortex Magnoliae Officinalis 10 parts, Flos Lonicerae 20 parts, Radix Scutellariae 10 parts, Rhizoma Coptidis 10 parts, Rhizoma Cimicifugae 9 parts, Semen Alpiniae Katsumadai 10 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| CN105125994A (en) * | 2015-09-16 | 2015-12-09 | 程俊 | Traditional Chinese medicine for treating oral ulcer |
| CN105194491A (en) * | 2015-09-21 | 2015-12-30 | 宋晓梅 | Traditional Chinese medicine composition for treating oral ulcers |
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Application publication date: 20150701 |
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