CN105017214B - 具有抗细菌活性的哌啶链接1,2,3‑三氮唑类化合物及其制备方法和应用 - Google Patents
具有抗细菌活性的哌啶链接1,2,3‑三氮唑类化合物及其制备方法和应用 Download PDFInfo
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- CN105017214B CN105017214B CN201510328611.3A CN201510328611A CN105017214B CN 105017214 B CN105017214 B CN 105017214B CN 201510328611 A CN201510328611 A CN 201510328611A CN 105017214 B CN105017214 B CN 105017214B
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- Prior art keywords
- piperidines
- triazole compounds
- antibacterial activity
- organic phase
- reaction
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- 238000002360 preparation method Methods 0.000 title claims abstract description 18
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- 238000003786 synthesis reaction Methods 0.000 claims abstract description 39
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- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract description 4
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- 239000003795 chemical substances by application Substances 0.000 description 5
- SYOANZBNGDEJFH-UHFFFAOYSA-N 2,5-dihydro-1h-triazole Chemical class C1NNN=C1 SYOANZBNGDEJFH-UHFFFAOYSA-N 0.000 description 4
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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