CN104965078A - Multi-channel fluorescence immunoassay quantitative analyzer - Google Patents

Multi-channel fluorescence immunoassay quantitative analyzer Download PDF

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Publication number
CN104965078A
CN104965078A CN201510380008.XA CN201510380008A CN104965078A CN 104965078 A CN104965078 A CN 104965078A CN 201510380008 A CN201510380008 A CN 201510380008A CN 104965078 A CN104965078 A CN 104965078A
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CN
China
Prior art keywords
fluorescence immunoassay
immunoassay quantitative
quantitative analysis
analysis instrument
instrument according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510380008.XA
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Chinese (zh)
Inventor
胡利刚
淳林
鲁加勇
肖之鹏
刘可
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NANJING PERLONG MEDICAL EQUIPMENT CO Ltd
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NANJING PERLONG MEDICAL EQUIPMENT CO Ltd
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Application filed by NANJING PERLONG MEDICAL EQUIPMENT CO Ltd filed Critical NANJING PERLONG MEDICAL EQUIPMENT CO Ltd
Priority to CN201510380008.XA priority Critical patent/CN104965078A/en
Publication of CN104965078A publication Critical patent/CN104965078A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The invention discloses a multi-channel fluorescence immunoassay quantitative analyzer. The multi-channel fluorescence immunoassay quantitative analyzer comprises a body, wherein a transmission assembly is arranged at one end of the body; a user interface, a mini-type printer and an infrared barcode scanner are arranged at the other end of the body; the infrared barcode scanner is located under the mini-type printer; the transmission assembly is provided with a main board, a light path assembly and an item automatic identification assembly in sequence from top to bottom; the bottom of the transmission assembly is connected with a bracket; the top end of the light path assembly is connected with a laser diode and a fluorescence reader respectively; a sample feeding disc is arranged above the bracket. The multi-channel fluorescence immunoassay quantitative analyzer adopts a multi-channel detection technology to realize simultaneous detection of a plurality of items of a single sample so that the detection efficiency is improved; a laser light source adopts the laser diode and has good singleness and high light source intensity, so that the high sensitivity and consistency are guaranteed; an automatic identification technology is used for realizing a measurement process and does not need manual interference so that the intelligent degree is high.

Description

A kind of multichannel fluorescence immunoassay quantitative analysis instrument
Technical field
The invention belongs to POCT clinical detection field of medical technology, specifically relate to a kind of hyperchannel fluorescence immunoassay quantitative analysis instrument.
Background technology
Real-time test POCT (point-of-care testing), refers to the clinical detection of carrying out on patient side, in this clinical detection field, adopts fluorescence immunoassay quantitative test detection technique, can realize the reliable testing result of quick obtaining.
Existing fluorescence analyzer mostly is single-channel and light source many employings light emitting diode, single-channel detects and cannot realize the detection of single sample entry, and a multiple project of sample needs repeated detection, and efficiency low velocity is slow, and when sample size is large, single-channel cannot meet detection demand; LED source unicity is poor, and luminous intensity is low, and fluorescence excitation efficiency reduces, thus causes detection efficiency to reduce and detection sensitivity reduction.
Therefore, need to propose a kind of novel fluorescence immunoassay quantitative analysis instrument.
Summary of the invention
Goal of the invention: in order to overcome the deficiencies in the prior art, the invention provides a kind of hyperchannel fluorescence immunoassay quantitative analysis instrument, can realize single sample entry and detect simultaneously, improve detection efficiency and detection sensitivity.
Technical scheme: for achieving the above object, hyperchannel fluorescence immunoassay quantitative analysis instrument of the present invention, comprise body, described body one end is provided with transmission component, the described body other end is provided with user interface, mini-printer and infrared barcode scanner, described infrared barcode scanner is positioned at the below of institute's mini-printer, described transmission component is provided with mainboard from top to bottom successively, optical path component and the automatic recognizer component of project, bracket is connected bottom described transmission component, described optical path component top connects laser diode and Fluorescent reader respectively, sample injection disc is provided with above described bracket.
Further, be provided with pallet above described sample injection disc, it is one group of passage that described pallet is divided evenly, and is equipped with detection dish in the passage above described pallet.
Further, described detection dish all adopts rectangular shape.
Further, the number range of described passage is 5 ~ 10.
Further, the number of described passage is 5.
Further, motor driver is connected below described user interface.
Further, Power conversion board is provided with directly over described body.
Further, described user interface is provided with measurement pattern and display screen, and described measurement pattern comprises quick pattern and mode standard.
Beneficial effect: compared with the prior art, the advantage had is in the present invention:
1, the present invention adopts multi-channel detection technology, realizes single sample entry and detects simultaneously, improve detection efficiency;
2, LASER Light Source adopts laser diode, and unicity is good, and the intensity of light source is high, ensure that high sensitivity and consistance;
3, employ automatic identification technology and achieve measuring process without the need to artificial interference, intelligence degree is high.
Accompanying drawing explanation
Fig. 1 is hyperchannel fluorescence immunoassay quantitative analysis instrument structural representation of the present invention.
In figure: 1, mainboard; 2, transmission component; 3, optical path component; 4, the automatic recognizer component of project; 5, bracket; 6, infrared barcode scanner; 7, user interface; 8, laser diode; 9, Fluorescent reader; 10, detection dish; 11, pallet; 12, sample injection disc; 13, motor driver; 14, mini-printer; 15, Power conversion board; 16, body.
Embodiment
Below in conjunction with accompanying drawing, the present invention is further described.
With reference to Fig. 1, the hyperchannel fluorescence immunoassay quantitative analysis instrument that the present invention proposes, comprise body 16, described body 16 one end is provided with transmission component 2, described body 16 other end is provided with user interface 7, mini-printer 14 and infrared barcode scanner 6, described user interface 7 is provided with measurement pattern and display screen, described measurement pattern comprises quick pattern and mode standard, described infrared barcode scanner 6 is positioned at the below of institute's mini-printer 14, described transmission component 2 is provided with mainboard 1 from top to bottom successively, optical path component 3 and the automatic recognizer component 4 of project, bracket 5 is connected bottom described transmission component 2, described optical path component 3 top connects laser diode 8 and Fluorescent reader 9 respectively, sample injection disc 12 is provided with above described bracket 5, pallet 11 is provided with above described sample injection disc 12, it is one group of passage that described pallet 11 is divided evenly, detection dish is equipped with in passage above described pallet 11, detection dish 10 is equipped with above described pallet 11, described detection dish 10 all adopts rectangular shape, the number range of described passage is 5 ~ 10, number as preferred described passage is 5, the number of described like this detection dish 10 is also 5, have employed the detection technique of Five-channel, motor driver 13 is connected below described user interface 7, Power conversion board 15 is provided with directly over described body 16, the Energy control that this Power conversion board 15 controls whole instrument connects,
Principle of work:
Power-on card extender 15 power switch, first will be equipped with the anticoagulant tube of sample near infrared barcode scanner 6 side, and infrared barcode scanner 6 can automatically identify bar code and record current sample bar code, can produce a new record;
Detector ejects sample injection disc 12, will the check-out console 10 detected be needed to put on pallet 11, and puts on sample injection disc 12, add blood sample on check-out console 10;
User interface 7 selects measurement pattern, choice criteria measurement pattern, the automatic warehouse entry of sample injection disc 12 meeting;
The automatic recognizer component 4 of project is started working, correspondence position on Scanning Detction panel, and automatically identifying needs test item, and according to working as quantity and the channel position of check-out console on front tray, instrument user interface 7 shows production respective items program recording;
Check-out console 10 adopts chromatography technology, analyze the form that thing forms immune complex in moving process, check-out console 10 excites generation fluorescence, obtain optical signalling, specifically laser diode 8 Emission Lasers is irradiated to check-out console 10 surface, check-out console 10 surface sends fluorescence, and fluorescence is irradiated on Fluorescent reader 9, and Fluorescent reader 9 obtains reading according to fluorescence;
Instrument can be hatched corresponding project according to being stored in respective items object brooding time on instrument, carries out whole process and scans and record corresponding data and carry out data processing, obtain respective items object result after time of arrival;
After all items all detects and terminates, sample injection disc 12 delivers from godown, and takes off pallet 11, abandons check-out console 12, detects and terminates.
The above is only the preferred embodiment of the present invention; be noted that for those skilled in the art; under the premise without departing from the principles of the invention, can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (8)

1. a hyperchannel fluorescence immunoassay quantitative analysis instrument, it is characterized in that: comprise body (16), described body (16) one end is provided with transmission component (2), described body (16) other end is provided with user interface (7), mini-printer (14) and infrared barcode scanner (6), described infrared barcode scanner (6) is positioned at the below of institute's mini-printer (14), described transmission component (2) is provided with mainboard (1) from top to bottom successively, optical path component (3) and the automatic recognizer component of project (4), described transmission component (2) bottom connects bracket (5), described optical path component (3) top connects laser diode (8) and Fluorescent reader (9) respectively, described bracket (5) top is provided with sample injection disc (12).
2. hyperchannel fluorescence immunoassay quantitative analysis instrument according to claim 1, it is characterized in that: described sample injection disc (12) top is provided with pallet (11), it is one group of passage that described pallet (11) is divided evenly, and is equipped with detection dish (10) in the passage of described pallet (11) top.
3. hyperchannel fluorescence immunoassay quantitative analysis instrument according to claim 2, is characterized in that: described detection dish (10) all adopts rectangular shape.
4. hyperchannel fluorescence immunoassay quantitative analysis instrument according to claim 2, is characterized in that: the number range of described passage is 5 ~ 10.
5. hyperchannel fluorescence immunoassay quantitative analysis instrument according to claim 4, is characterized in that: the number of described passage is 5.
6. hyperchannel fluorescence immunoassay quantitative analysis instrument according to claim 1, is characterized in that: described user interface (7) below connects motor driver (13).
7. hyperchannel fluorescence immunoassay quantitative analysis instrument according to claim 1, is characterized in that: be provided with Power conversion board (15) directly over described body (16).
8. hyperchannel fluorescence immunoassay quantitative analysis instrument according to claim 1, is characterized in that: described user interface (7) is provided with measurement pattern and display screen, and described measurement pattern comprises quick pattern and mode standard.
CN201510380008.XA 2015-07-01 2015-07-01 Multi-channel fluorescence immunoassay quantitative analyzer Pending CN104965078A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105548020A (en) * 2015-12-09 2016-05-04 苏州德沃生物技术有限公司 Full-automatic multichannel biochemical detector and detection method thereof
CN113156109A (en) * 2021-03-16 2021-07-23 广州埃克森生物科技有限公司 Multifunctional immune quantitative analyzer and implementation method thereof
CN113985020A (en) * 2021-11-08 2022-01-28 山东理工大学 A multichannel reads a equipment for food safety short-term test

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105548020A (en) * 2015-12-09 2016-05-04 苏州德沃生物技术有限公司 Full-automatic multichannel biochemical detector and detection method thereof
CN105548020B (en) * 2015-12-09 2018-09-18 苏州德沃生物技术有限公司 Fully-automatic multi-channel biochemical detection device and its detection method
CN113156109A (en) * 2021-03-16 2021-07-23 广州埃克森生物科技有限公司 Multifunctional immune quantitative analyzer and implementation method thereof
CN113985020A (en) * 2021-11-08 2022-01-28 山东理工大学 A multichannel reads a equipment for food safety short-term test

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Application publication date: 20151007

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