CN104906229A - Traditional Chinese medicine gel preparation for treating cervicitis - Google Patents
Traditional Chinese medicine gel preparation for treating cervicitis Download PDFInfo
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- CN104906229A CN104906229A CN201510308664.9A CN201510308664A CN104906229A CN 104906229 A CN104906229 A CN 104906229A CN 201510308664 A CN201510308664 A CN 201510308664A CN 104906229 A CN104906229 A CN 104906229A
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Abstract
The invention discloses a traditional Chinese medicine gel preparation for treating cervicitis. The traditional Chinese medicine gel preparation is prepared from, by weight, 15-20 parts of fructus forsythia, 10-15 parts of honeysuckle, 5-10 parts of isatis roots, 5-10 parts of cortex dictamni, 5-10 parts of circium japonicum, 5-10 parts of rhizoma cibotii, 5-10 parts of herba glechomae, 3-6 parts of endothelium corneum gigeriae galli, 3-6 parts of caulis sinomenii, 0.05-0.1 part of alums, 25-35 parts of substrate gel, 80-100 parts of humectants, 0.3-0.6 part of preservative and 600-800 parts of water. One or several of carbomer 940, carboxymethyl cellulose sodium, chitin, agar, gelatin and starch is or are selected as the substrate gel. The humectants are glycerinum or propylene glycol. The preservative is sodium benzoate or benzoic acid or benzalkonium bromide or chlorhexidine acetat or sorbic acid and sorbate or ethylparaben. The invention further discloses a preparation method of the traditional Chinese medicine gel preparation. The traditional Chinese medicine gel preparation for treating cervicitis has the advantages of being good in curative effect, instant in effect, free of toxic and side effects, easy to prepare, convenient to take, simple in material drawing and low in price.
Description
Technical field
The present invention relates to a kind of Traditional Chinese medicinal gel preparation for the treatment of cervicitis, belong to technical field of medicine.
Background technology
Cervicitis is for being gynecological's common disease, be mainly in Women of Childbearing Age, be the key factor causing inflammatory disease of pelvic organs, many relevant with parillomarvirus infections, disease time is lasting and be easy to repeatedly, the life quality of severe jamming women, even whole quality of life, if treat not in time. and also can develop into Cervical cancer, be the very common pertinacious diseases of the women of child-bearing age, painful large, sickness rate is high.Cervicitis is divided into acute and chronic two kinds, common with chronic cervicitis.Cervicitis main manifestations is leucorrhoea grow in quantity, in purulence, or has abnormal bleeding as intermenstrual bleeding, postcoital bleeding etc., often with the soreness of waist and hypogastric region discomfort.
Although the medicine of current treatment chronic cervicitis is a lot, all fundamentally cannot treats, without satisfactory effect, and have certain side effect.Generally adopt antibiotic therapy clinically, but long-time application antibiotic easily causes collective's dysbacteriosis and uncertain therapeutic efficacy is cut.The method of naturopathy has electrocoagulation, laser therapy, cryotherapy.Shortcoming is that side effect is comparatively large, vaginal walls nerve sensitivity likely can be caused to reduce, have impact to life quality.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of Traditional Chinese medicinal gel preparation for the treatment of cervicitis, its good effect, instant effect, has no side effect, and preparation is simple, cheap.
For achieving the above object, the present invention adopts following technical proposals:
Treating a Traditional Chinese medicinal gel preparation for cervicitis, is be made up of the raw material of following weight portion:
Fructus Forsythiae 15 ~ 20 parts, Flos Lonicerae 10 ~ 15 parts, Radix Isatidis 5 ~ 10 parts, Cortex Dictamni 5 ~ 10 parts, Radix Cirsii Japonici 5 ~ 10 parts, Rhizoma Cibotii 5 ~ 10 parts, Herba Glechomae 5 ~ 10 parts, Endothelium Corneum Gigeriae Galli 3-6 part, Caulis Sinomenii 3-6 part, 0.05 ~ 0.1 part, Alumen, gel-type vehicle 25-35 part, wetting agent 80-100 part, antiseptic 0.3-0.6 part, water 600-800 part.
Described gel-type vehicle is selected from the one or several arbitrarily in Acritamer 940, Carboxymethyl cellulose sodium, chitin, agar, gelatin or starch; Be preferably Acritamer 940 or Carboxymethyl cellulose sodium.
Described wetting agent is glycerol or propylene glycol; Be preferably glycerol.
Described antiseptic is that sodium benzoate, benzoic acid, benzalkonium bromide, acetic acid chloroethene are fixed, sorbic acid and its esters or ethyl hydroxybenzoate.
Preferably, the Traditional Chinese medicinal gel preparation of this treatment cervicitis is made up of the raw material of following weight portion:
Fructus Forsythiae 17 ~ 19 parts, Flos Lonicerae 12 ~ 14 parts, Radix Isatidis 7 ~ 9 parts, Cortex Dictamni 7 ~ 9 parts, Radix Cirsii Japonici 7 ~ 9 parts, Rhizoma Cibotii 7 ~ 9 parts, Herba Glechomae 7 ~ 9 parts, Endothelium Corneum Gigeriae Galli 4-6 part, Caulis Sinomenii 4-6 part, 0.05 ~ 0.1 part, Alumen, gel-type vehicle 30-35 part, wetting agent 80-90 part, antiseptic 0.3-0.6 part, water 600-800 part.
Preferred further, the Traditional Chinese medicinal gel preparation of this treatment cervicitis is made up of the raw material of following weight portion:
Fructus Forsythiae 18 parts, Flos Lonicerae 13 parts, Radix Isatidis 8 parts, Cortex Dictamni 8 parts, Radix Cirsii Japonici 8 parts, Rhizoma Cibotii 8 parts, Herba Glechomae 8 parts, Endothelium Corneum Gigeriae Galli 8 parts, Caulis Sinomenii 8 parts, 0.08 part, Alumen, gel-type vehicle 32 parts, wetting agent 85 parts, antiseptic 0.5 part, 700 parts, water.
The preparation method of the Traditional Chinese medicinal gel preparation for the treatment of cervicitis of the present invention, step is as follows:
(1) Fructus Forsythiae, Flos Lonicerae, Radix Isatidis, Cortex Dictamni, Radix Cirsii Japonici, Rhizoma Cibotii, Herba Glechomae, Endothelium Corneum Gigeriae Galli and Caulis Sinomenii is got, add the alcoholic solution of 8-10 times of weight, extract, filter, merging filtrate, it is 1.20-1.25 (50 DEG C of surveys) that filtrate is concentrated into relative density, dry, pulverize, sieve, obtain extract, for subsequent use;
(2) Alumen is ground to form fine powder, the extract prepared with step (1) mixes, and is dissolved in water, and the pH value regulating solution is 4.0 ~ 5.0;
(3) in gel-type vehicle, add wetting agent, mixing, after placing 30-60min, join in the solution of step (2), add antiseptic simultaneously, stir, sterilizing, to obtain final product.
In step (1), the volume fraction of described alcoholic solution is 60-70%.
In step (1), the number of times of extraction is 3 times, and each time of extracting is 1-2 hour.
In step (2), what regulate the pH value of solution to adopt is dilute hydrochloric acid.
In step (3), sterilising conditions is: 100 DEG C of flowing steam sterilizations 30 ~ 40 minutes.
The consumption of Traditional Chinese medicinal gel preparation of the present invention, by active component crude drug total weight, is 1-20 gram/day, can smears every day once or secondary.
The Traditional Chinese medicinal gel preparation for the treatment of cervicitis of the present invention, the pharmacological property of its each crude drug is as follows:
Fructus Forsythiae: cool in nature, bitter in the mouth is nontoxic.Heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Can control warm, erysipelas, macule etc.
Flos Lonicerae: cold in nature, sweet in the mouth.There is heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cure mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.
Radix Isatidis: bitter, cold.Heat-clearing and toxic substances removing, removing heat from blood, sore-throat relieving.
Cortex Dictamni: bitter, cold.Return spleen, stomach, urinary bladder channel.Heat clearing and damp drying, removing toxic substances of dispeling the wind.For damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, beriberoid pyretic arthralgia, jaundice dark coloured urine.
Radix Cirsii Japonici: sweet, bitter, cold.GUIXIN, Liver Channel.Cooling blood for hemostasis, dissipating blood stasis removing toxicity for eliminating carbuncles.
Rhizoma Cibotii: bitter, sweet, temperature.Return liver, kidney channel.Wind-damp dispelling, invigorating the liver and kidney, strong waist knee joint.For rheumatic arthralgia, soreness of the waist and knees, weakness of the lower extremities
Herba Glechomae: pungent, micro-hardship, is slightly cold.Return liver, kidney, urinary bladder channel.Dampness removing is treating stranguria, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.
Endothelium Corneum Gigeriae Galli: sweet is flat.Return spleen, stomach, small intestinal, urinary bladder channel.Invigorating the stomach and promoting digestion, arresting seminal emission, treating stranguria fossil.
Caulis Sinomenii: bitter, pungent is flat.Return liver, spleen channel.Wind-damp dispelling, the meridian dredging, diuresis.For rheumatic arthralgia, arthroncus, paralysis pruritus.
It is monarch drug that the present invention chooses Fructus Forsythiae, removing toxic substances, detumescence, and Flos Lonicerae is ministerial drug, and removing toxic substances, antiinflammatory, help with Radix Isatidis, Cortex Dictamni, Radix Cirsii Japonici, Rhizoma Cibotii, Herba Glechomae, Endothelium Corneum Gigeriae Galli and Caulis Sinomenii; Each medicine share, and compatibility is reasonable, clear curative effect, removing toxic substances, detumescence, antiinflammatory, meets primary disease treatment.
Beneficial effect of the present invention:
The Traditional Chinese medicinal gel preparation for the treatment of cervicitis of the present invention, through clinical verification for many years, good effect, instant effect, has no side effect, and preparation is simple, easy to use, cheap, can be used for treatment cervicitis and precancerous lesions of uterine cervix.
Detailed description of the invention
Below by instantiation, the present invention will be further elaborated, should be noted that following explanation is only to explain the present invention, not limiting its content.
Embodiment 1: the preparation being used for the treatment of the Traditional Chinese medicinal gel preparation of cervicitis
Formula: Fructus Forsythiae 18 kilograms, Flos Lonicerae 13 kilograms, Radix Isatidis 8 kilograms, Cortex Dictamni 8 kilograms, Radix Cirsii Japonici 8 kilograms, Rhizoma Cibotii 8 kilograms, Herba Glechomae 8 kilograms, Endothelium Corneum Gigeriae Galli 8 kilograms, Caulis Sinomenii 8 kilograms, 0.08 kilogram, Alumen, gel-type vehicle 32 kilograms, wetting agent 85 kilograms, antiseptic 0.5 kilogram, 700 kilograms, water.
Wherein, gel-type vehicle is sodium carboxymethyl cellulose; Wetting agent is glycerol; Antiseptic is ethyl hydroxybenzoate.
Preparation method:
Take clean Fructus Forsythiae, Radix Isatidis, Flos Lonicerae, Cortex Dictamni, Radix Cirsii Japonici, Rhizoma Cibotii, Herba Glechomae, Endothelium Corneum Gigeriae Galli and Caulis Sinomenii in proportion, add 70% ethanol of 120 liters, extract 3 times, each 1.5 hours, filter, merging filtrate, volatilization ethanol, be evaporated to the thick paste that relative density is 1.20,50 DEG C of vacuum dryings, pulverize, and cross 80 mesh sieves, obtain extract, for subsequent use;
Alumen is ground to form fine powder, crosses 80 mesh sieves, mix with Chinese medicine extract, add water, be heated to dissolve completely, with dilute hydrochloric acid adjust ph to 4.0, obtain A liquid.CMC-Na (sodium carboxymethyl cellulose is taken according to crude drug ratio, glycerol adding fully mixes, place and slowly add A liquid after about 30 minutes, add ethyl hydroxybenzoate, limit edged stirs to evenly simultaneously, then after placing 2 hours, stir evenly in rearmounted infusion bottle, capping, in 100 DEG C of flowing steam sterilizations 30 minutes, subpackage and get final product.
Embodiment 2: the preparation being used for the treatment of the Traditional Chinese medicinal gel preparation of cervicitis:
Formula: Fructus Forsythiae 15 kilograms, Flos Lonicerae 15 kilograms, Radix Isatidis 5 kilograms, Cortex Dictamni 10 kilograms, Radix Cirsii Japonici 5 kilograms, Rhizoma Cibotii 10 kilograms, Herba Glechomae 5 kilograms, Endothelium Corneum Gigeriae Galli 6 kilograms, Caulis Sinomenii 3 kilograms, 0.1 kilogram, Alumen, gel-type vehicle 25 kilograms, wetting agent 100 kilograms, antiseptic 0.3 kilogram, 800 kilograms, water.
Wherein, gel-type vehicle is sodium carboxymethyl cellulose; Wetting agent is glycerol; Antiseptic is sodium benzoate.
Preparation method is with embodiment 1.
Embodiment 3: the preparation being used for the treatment of the Traditional Chinese medicinal gel preparation of cervicitis
Formula: Fructus Forsythiae 20 kilograms, Flos Lonicerae 10 kilograms, Radix Isatidis 10 kilograms, Cortex Dictamni 5 kilograms, Radix Cirsii Japonici 10 kilograms, Rhizoma Cibotii 5 kilograms, Herba Glechomae 10 kilograms, Endothelium Corneum Gigeriae Galli 3 kilograms, Caulis Sinomenii 6 kilograms of parts, 0.05 kilogram, Alumen, gel-type vehicle 35 kilograms, wetting agent 80 kilograms, antiseptic 0.6 kilogram, 600 kilograms, water.
Wherein, gel-type vehicle is sodium carboxymethyl cellulose; Wetting agent is glycerol; Antiseptic is sorbic acid.
Preparation method is with embodiment 1.
Embodiment 4: the preparation being used for the treatment of the Traditional Chinese medicinal gel preparation of cervicitis
Formula: Fructus Forsythiae 17 kilograms, Flos Lonicerae 14 kilograms, Radix Isatidis 7 kilograms, Cortex Dictamni 9 kilograms, Radix Cirsii Japonici 7 kilograms, Rhizoma Cibotii 9 kilograms, Herba Glechomae 7 kilograms, Endothelium Corneum Gigeriae Galli 6 kilograms, Caulis Sinomenii 4 kilograms, 0.1 kilogram, Alumen, gel-type vehicle 30 kilograms, wetting agent 90 kilograms, antiseptic 0.3 kilogram, 800 kilograms, water.
Wherein, gel-type vehicle is sodium carboxymethyl cellulose; Wetting agent is glycerol; Antiseptic is sorbic acid.
Preparation method is with embodiment 1.
Embodiment 5: the preparation being used for the treatment of the Traditional Chinese medicinal gel preparation of cervicitis
Formula: Fructus Forsythiae 19 kilograms, Flos Lonicerae 12 kilograms, Radix Isatidis 9 kilograms, Cortex Dictamni 7 kilograms, Radix Cirsii Japonici 9 kilograms, Rhizoma Cibotii 7 kilograms, Herba Glechomae 9 kilograms, Endothelium Corneum Gigeriae Galli 4 kilograms, Caulis Sinomenii 6 kilograms, 0.05 kilogram, Alumen, gel-type vehicle 35 kilograms, wetting agent 80 kilograms, antiseptic 0.6 kilogram, 600 kilograms, water.
Wherein, gel-type vehicle is sodium carboxymethyl cellulose; Wetting agent is glycerol; Antiseptic is sorbic acid.
Preparation method is with embodiment 1.
Clinical verification
1. physical data:
2012 routine to the samples from Patients with Chronic Cervicitis 80 that 2014 Nian Lai institutes are medical, and the age of patient was at 26 ~ 42 years old.Before and after all case treatments, all routine carries out gynecologial examination, leucorrhea routine examination, and gets rid of colpitis mycotica and trichomonal vaginitis through smear for microscopic examination, and cervical cancer got rid of by cervical scraping smear.
2. diagnostic criteria:
Leucorrhoea grow in quantity, in yellow, purulence or band courage and uprightness, have lumbosacral region pain or contact bleeding.Gynecologial examination: cervical surface takes on a red color, has erosion in various degree, hypertrophy, and rotten to the corn face and normal group are woven with obvious boundary, is coated with iodine solution not painted, can has contact bleeding.
3. Therapeutic Method:
Patient is divided at random treatment 1 group, treats 2 groups, treats 3 groups and matched group, often organize 20 people.Treat 1 group of Traditional Chinese medicinal gel preparation adopting the embodiment of the present invention 1 to prepare, smear affected part every day 2 times, being used in conjunction 7 is a course for the treatment of.Healing person, does not re-use.Unhealed, proceeds the next course for the treatment of; Treat 2 groups, treat 3 groups of Traditional Chinese medicinal gel preparations adopting the embodiment of the present invention 2, embodiment 3 to prepare respectively, use with treatment 1 group.
Matched group adopts sport gel agent of relaxing, and by specification is taken or followed the doctor's advice.
4. curative effect judging standard:
Cure: lesion smooth surface, be entirely newborn squamous epithelial cancer and cover;
Effective: lesion area reduces > 30%, major part is that newborn squamous epithelial cancer covers;
Invalid: lesion covers without obvious newborn squamous epithelial cancer.
5. therapeutic outcome:
Most of patients uses to take effect 2 ~ 3 courses for the treatment of, and 3 ~ 4 courses for the treatment of cure, the course of disease is longer, the state of an illness than more severe case, need with 5 ~ 6 courses for the treatment of.Take the therapeutic outcome after 5 courses for the treatment of in table 1.
Table 1 therapeutic outcome
Group | Number of cases | Cure | Effectively | Invalid | Total effective rate (%) |
Treat 1 group | 20 | 15 | 5 | 0 | 100 |
Treat 2 groups | 20 | 15 | 4 | 1 | 95 |
Treat 3 groups | 20 | 16 | 4 | 0 | 100 |
Matched group | 20 | 14 | 4 | 2 | 90 |
As can be seen from Table 1, adopt the average total effective rate of Chinese medicine preparation of the present invention more than 98.3%, be obviously better than matched group, in process of clinical application, all do not occur toxicity, side effect.
Model case
1, Zhang, female, 30 years old, patient found cervicitis before 4 years, leucorrhoea grow in quantity, sometimes in secretions with the blood streak, lower abdomen is pain sometimes.Use medicine of the present invention (embodiment 1) to treat, after treating for 4 courses for the treatment of, transference cure, continues use 1 the lasting effects course for the treatment of; Pay a return visit after half a year, have no recurrence.
2, Cai so-and-so, female, 42 years old, for many years, vaginal secretions increased Chronic cervicitis, in yellow, was sometimes with purulence, time have contact bleeding, gynecologial examination finds that cervix uteri be that rotten to the corn sample changes, and has yellow secretions covering cervical orifice.Use medicine of the present invention (embodiment 1) to treat, after treating for 4 courses for the treatment of, symptom obviously alleviates, and continues 2 courses for the treatment of of use, cures.Recurrence of following up a case by regular visits to that so far there are no.
The above; be only the present invention's preferably detailed description of the invention; but protection scope of the present invention is not limited thereto; any those skilled in the art of being familiar with are in the technical scope that the present invention discloses; be equal to according to technical scheme of the present invention and inventive concept thereof and replace or change, all should be encompassed within protection scope of the present invention.
Claims (10)
1. treating a Traditional Chinese medicinal gel preparation for cervicitis, it is characterized in that, is be made up of the raw material of following weight portion:
Fructus Forsythiae 15 ~ 20 parts, Flos Lonicerae 10 ~ 15 parts, Radix Isatidis 5 ~ 10 parts, Cortex Dictamni 5 ~ 10 parts, Radix Cirsii Japonici 5 ~ 10 parts, Rhizoma Cibotii 5 ~ 10 parts, Herba Glechomae 5 ~ 10 parts, Endothelium Corneum Gigeriae Galli 3-6 part, Caulis Sinomenii 3-6 part, 0.05 ~ 0.1 part, Alumen, gel-type vehicle 25-35 part, wetting agent 80-100 part, antiseptic 0.3-0.6 part, water 600-800 part;
Described gel-type vehicle is selected from the one or several arbitrarily in Acritamer 940, Carboxymethyl cellulose sodium, chitin, agar, gelatin or starch;
Described wetting agent is glycerol or propylene glycol;
Described antiseptic is that sodium benzoate, benzoic acid, benzalkonium bromide, acetic acid chloroethene are fixed, sorbic acid and its esters or ethyl hydroxybenzoate.
2. the Traditional Chinese medicinal gel preparation for the treatment of cervicitis as claimed in claim 1, it is characterized in that, be made up of the raw material of following weight portion:
Fructus Forsythiae 17 ~ 19 parts, Flos Lonicerae 12 ~ 14 parts, Radix Isatidis 7 ~ 9 parts, Cortex Dictamni 7 ~ 9 parts, Radix Cirsii Japonici 7 ~ 9 parts, Rhizoma Cibotii 7 ~ 9 parts, Herba Glechomae 7 ~ 9 parts, Endothelium Corneum Gigeriae Galli 4-6 part, Caulis Sinomenii 4-6 part, 0.05 ~ 0.1 part, Alumen, gel-type vehicle 30-35 part, wetting agent 80-90 part, antiseptic 0.3-0.6 part, water 600-800 part.
3. the Traditional Chinese medicinal gel preparation for the treatment of cervicitis as claimed in claim 1, it is characterized in that, be made up of the raw material of following weight portion:
Fructus Forsythiae 18 parts, Flos Lonicerae 13 parts, Radix Isatidis 8 parts, Cortex Dictamni 8 parts, Radix Cirsii Japonici 8 parts, Rhizoma Cibotii 8 parts, Herba Glechomae 8 parts, Endothelium Corneum Gigeriae Galli 8 parts, Caulis Sinomenii 8 parts, 0.08 part, Alumen, gel-type vehicle 32 parts, wetting agent 85 parts, antiseptic 0.5 part, 700 parts, water.
4. the Traditional Chinese medicinal gel preparation of the treatment cervicitis as described in claim 1,2 or 3, is characterized in that, described gel-type vehicle is selected from Acritamer 940 or Carboxymethyl cellulose sodium.
5. the Traditional Chinese medicinal gel preparation of the treatment cervicitis as described in claim 1,2 or 3, is characterized in that, described wetting agent is glycerol.
6. the preparation method of the Traditional Chinese medicinal gel preparation of the treatment cervicitis described in any one of claim 1 to 5, it is characterized in that, step is as follows:
(1) Fructus Forsythiae, Flos Lonicerae, Radix Isatidis, Cortex Dictamni, Radix Cirsii Japonici, Rhizoma Cibotii, Herba Glechomae, Endothelium Corneum Gigeriae Galli and Caulis Sinomenii is got, add the alcoholic solution of 8-10 times of weight, extract, filter, merging filtrate, it is 1.20-1.25 that filtrate is concentrated into relative density, dry, pulverize, sieve, obtain extract, for subsequent use;
(2) Alumen is ground to form fine powder, the extract prepared with step (1) mixes, and is dissolved in water, and the pH value regulating solution is 4.0 ~ 5.0;
(3) in gel-type vehicle, add wetting agent, mixing, after placing 30-60min, join in the solution of step (2), add antiseptic simultaneously, stir, sterilizing, to obtain final product.
7. preparation method as claimed in claim 6, it is characterized in that, in step (1), the volume fraction of described alcoholic solution is 60-70%.
8. preparation method as claimed in claim 6, it is characterized in that, in step (1), the number of times of extraction is 3 times, and each time of extracting is 1-2 hour.
9. preparation method as claimed in claim 6, is characterized in that, in step (2), what regulate the pH value of solution to adopt is dilute hydrochloric acid.
10. preparation method as claimed in claim 6, it is characterized in that, in step (3), sterilising conditions is: 100 DEG C of flowing steam sterilizations 30 ~ 40 minutes.
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1739580A (en) * | 2005-09-13 | 2006-03-01 | 潘金火 | Recipe and prepn process of Chinese medicine gel prepn |
ES2462553A1 (en) * | 2014-01-16 | 2014-05-23 | Gepnes Hattrick Sl | Composition for improvement of sexual well-being (Machine-translation by Google Translate, not legally binding) |
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2015
- 2015-06-08 CN CN201510308664.9A patent/CN104906229A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1739580A (en) * | 2005-09-13 | 2006-03-01 | 潘金火 | Recipe and prepn process of Chinese medicine gel prepn |
ES2462553A1 (en) * | 2014-01-16 | 2014-05-23 | Gepnes Hattrick Sl | Composition for improvement of sexual well-being (Machine-translation by Google Translate, not legally binding) |
Non-Patent Citations (1)
Title |
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弭阳: "《妇科病治验》", 31 March 2015, 山东大学出版社 * |
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Application publication date: 20150916 |