CN104887757B - The Chinese medicine composition and massage cream of freeing vessels and nourishing heart - Google Patents
The Chinese medicine composition and massage cream of freeing vessels and nourishing heart Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition of freeing vessels and nourishing heart and massage cream, the Chinese medicine composition is prepared by the raw material extraction of following parts by weight: 5-38 parts of Radix Astragali, 5-18 parts of ramulus cinnamomi, 1-20 parts of radix cyathulae, 10-30 parts of Snakegourd Fruit, 15-35 parts of pheretima, 3-20 parts of Rhizoma Chuanxiong.The massage cream is that common matrix or carrier are prepared in Chinese medicine composition and cosmetics by the freeing vessels and nourishing heart.The raw material of the Chinese medicine composition of freeing vessels and nourishing heart of the invention is according to the theory of Chinese medicine " monarch ", and made of compatibility, addition Radix Astragali, ramulus cinnamomi are monarch, has the effect of tonifying Qi and lifting yang, warming and activating meridian；Addition radix cyathulae is minister, has the effect of dispelling stasis of blood and stimulating the menstrual flow；Snakegourd Fruit, pheretima are added as assistant, there is the effect of heat-clearing dredging collateral；Addition Rhizoma Chuanxiong is to make, and has the effect of blood-activating and qi-promoting；Massage cream of the present invention is used for freeing vessels and nourishing heart good effect, safety and stability, has no toxic side effect, without drug dependence.
Description
Technical field
The invention belongs to Chinese medicine external product fields, more particularly to the Chinese medicine composition and massage cream of a kind of freeing vessels and nourishing heart.
Background technique
Chest impediment and cardialgia sees " Synopsis Golden Chamber chest impediment and cardialgia lose heart abnormal pulse card control " piece earliest, is one of common clinical disease,
It is due to healthy tendency internal weakness, phlegm is turbid, extravasated blood, the stagnation of the circulation of vital energy, cold solidifying and cause heart vessel blockage stasis unsmooth, clinical in wingceltis or left chest is ictal
Feel oppressed, pain or shouting pain are a kind of illness mainly showed.With the change of modern society's life mode and dietary structure, the disease
Have the tendency that gradually increasing, is one of the important disease of heart system for threatening middle-aged and the old's life and health.This disease has complicated clinic
Performance and pathological change, and traditional Chinese medicine has a unique theoretical and clinical experience abundant to the treatment of " chest impediment and cardialgia ", treatment from
Entirety is set out, the advantage with comprehensive function, because receiving significant attention.
It is early on the books to this disease treatment in China's medical book.Such as " Ling Shu Miraculous Pivot or Divine Axis faint a disease piece ": " angina pectoris, bluish colour of the limbs extending up to the elbows and knees,
It is pained very, onset of disease in the morning and dying in the evening, onset of disease in the evening and dying in the next morning.".Such as " prescriptions worth thousand gold " cloud: " thoracic obstruction has colic pain as pierced ...." " a few days dead " " gold is not controlled
Deficient outline " emphasize a surname's numbness activate yang based on principle of reatment, still followed so far to be clinical.Later age doctor has also been proposed activating microcirculation and removing stasis medicinal
Principle of reatment, such as " Standards of Diagnosis and Treatment, all pain doors " with big agent safflower, peach kernel, dalbergia wood, Shixiao San treatment epigastric pain due to blood stasis；" Shi Fangge
Include " use Danshen；Errors in Medicine Corrected Chinese drugs etc. treat chest impediment and cardialgia.
Suxiao jiuxin pills, Fufang Danshen Pian, Suhexian Wan, storax pill for treating coronary heart disease, Shexiang Baoxin Pills etc. are all chest impediment and cardialgias
Common medicine, this kind of medicine can alleviate the adverse reactions such as headache, dizziness caused by symptom and Western medicine nitroglycerin.Coronary disease Soviet Union closes
Ball belongs to first aid medicine, after the number of angina pectoris attacks is reduced or disappeared, then should use other drugs instead.The disease that symptoms are mild
People then should not continuously take these drugs for a long time.Fufang Danshen Pian is then made of Radix Salviae Miltiorrhizae, Radix Notoginseng, borneol, is mostly used, long with can consume
Impairment of QI-blood, it is unfavorable to the state of an illness, in addition, the ingredient having in oral Chinese patent medicine has stronger stimulation to human body alimentary canal, therefore
Chest impediment and cardialgia, which merges esophagitis and stomach patient, to be used with caution.
It is therefore desirable to both can solve oral in view of the above-mentioned problems, research and develop a kind of Chinese medicine external product conveniently, safely used
Stimulation of the product to enteron aisle, and have effects that freeing vessels and nourishing heart.
Summary of the invention
Based on this, in order to overcome the above-mentioned problems of the prior art, the present invention provides a kind of safety and stability, curative effect
It gets well, have no toxic side effect, the Chinese medicine composition and massage cream and preparation method thereof of freeing vessels and nourishing heart without drug dependence.
In order to achieve the above-mentioned object of the invention, this invention takes specific technical solutions below:
A kind of Chinese medicine composition of freeing vessels and nourishing heart, the Chinese medicine composition by following parts by weight raw material extract preparation and
At: 5-38 parts of Radix Astragali, 5-18 parts of ramulus cinnamomi, 1-20 parts of radix cyathulae, 10-30 parts of Snakegourd Fruit, 15-35 parts of pheretima, 3-20 parts of Rhizoma Chuanxiong.
In wherein some embodiments, the Chinese medicine composition is prepared by the raw material extraction of following parts by weight: Radix Astragali
10-25 parts, 7-15 parts of ramulus cinnamomi, 5-15 parts of radix cyathulae, 15-25 parts of Snakegourd Fruit, 22-28 parts of pheretima, 5-15 parts of Rhizoma Chuanxiong.
The Chinese medicine composition is prepared by the raw material extraction of following parts by weight in one of the embodiments: Radix Astragali
21 parts, 11 parts of ramulus cinnamomi, 11 parts of radix cyathulae, 21 parts of Snakegourd Fruit, 25 parts of pheretima, 11 parts of Rhizoma Chuanxiong.
The pharmacological action difference of each raw material is as follows in the Chinese medicine composition of freeing vessels and nourishing heart of the present invention:
Radix Astragali: sweet, tepor, tonifying Qi and lifting yang, strengthening exterior and reducing sweat, inducing diuresis for removing edema, shengjin nourishing, move stagnation and palsy etc. are used for the deficiency of vital energy
It is out of strength, the sinking of qi of middle-jiao, exterior deficiency spontaneous perspiration etc..Ramulus cinnamomi: acrid, sweet, warm, inducing sweat and dispelling exogenous evils, warming meridian, help yang gas, flat and gas are used
In blood trembles with fear Amenorrhea, palpitaition etc..Radix cyathulae: sweet, slight bitter is put down, dispelling stasis of blood and stimulating the menstrual flow, inducing diuresis for treating strangurtia, for rheumatic arthralgia etc..Snakegourd Fruit: sweet,
Slight bitter is trembled with fear, clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, and moisturizing dryness and lubricating intestine is used for cough with lung heat, chest impediment and cardialgia etc..Pheretima: it is salty, it trembles with fear, heat-clearing is fixed
Frightened, dredging collateral is relievingd asthma, and is used for arthralgia, extremity numbness etc..Rhizoma Chuanxiong: acrid in flavour and warm in nature, blood-activating and qi-promoting, wind-expelling pain-stopping are used for the thoracic obstruction heart
Bitterly, sternal rib shouting pain etc..
The Chinese medicine composition of freeing vessels and nourishing heart of the present invention the preparation method comprises the following steps: weigh traditional Chinese medicinal material raw materials, be sufficiently mixed or
It is mixed after crushing, the ethyl alcohol that suitable water or different quality containing is added is extracted according to general extraction methods in industry, is obtained
To concentrating filter liquor after obtain the Chinese medical extract of freeing vessels and nourishing heart.
The present invention also provides application of the above-mentioned Chinese medicine composition in the exterior-applied article for preparing freeing vessels and nourishing heart.
In wherein some embodiments, the exterior-applied article be massage cream, the massage cream by above-mentioned freeing vessels and nourishing heart Chinese medicine
Common matrix or carrier are prepared in composition and cosmetics, and the matrix or carrier include emulsifier, excipient, soft and moist
Agent, conditioner, moisturizer, suspending agent, covering agent, chelating agent, water, preservative, essence.
A kind of massage cream of freeing vessels and nourishing heart, the massage cream is using above-mentioned Chinese medicine composition as effective component.
In wherein some embodiments, the massage cream is prepared by the raw material of following weight percent: the massage
Cream is prepared by the raw material of following weight percent: the Chinese medicine composition 11-30% of freeing vessels and nourishing heart, emulsifier 5.3-9.3%,
Excipient 2.0-6.0%, emollients 10.0-14.0%, conditioner 0.27-0.67%, moisturizer 11.0-13.0%, suspending agent
0.35%-0.75%, covering agent 0.3-0.7%, chelating agent 0.02-0.07%, water 38.83-42.83%, preservative 0-
1.5%, essence 0-0.4%.
The massage cream is prepared by the raw material of following weight percent in one of the embodiments: freeing vessels and nourishing heart
Chinese medical extract 20%, stereth -21.8%, stereth -212.0%, PEG-100 stearate 2.5%, sweet
Oleostearin acid esters 1.0%, cetostearyl alcohol 4.0%, carbonic acid dioctyl ester 5.0%, isopropyl myristate 5.0%, poly dimethyl
Siloxanes 2.0%, tocopherol acetate 0.1%, bisabolol 0.05%, water 40.83%, 1,3- propylene glycol 5.0%, xanthan gum
0.3%, mosanom 0.25%, EDETATE SODIUM 0.05%, glycine betaine 1.0%, allantoin 0.1%, panthenol 0.2%, titanium dioxide
0.5%, glycerol 5.0%, butanediol 2.0%, tetrahydro piperine 0.02%, methylisothiazolinone/Chlorphenesin 0.6%, benzene
Oxyethanol/Sensiva SC50 0.5%, essence 0.2%.
Compared with prior art, the invention has the following advantages:
1, the raw material of the Chinese medicine composition of freeing vessels and nourishing heart of the invention be according to the theory of Chinese medicine " monarch ", compatibility and
At, addition Radix Astragali, ramulus cinnamomi are monarch, have the effect of tonifying Qi and lifting yang, warming and activating meridian；Addition radix cyathulae is minister, is had logical by the stasis of blood
Through the effect of；Snakegourd Fruit, pheretima are added as assistant, there is the effect of heat-clearing dredging collateral；Addition Rhizoma Chuanxiong is to make, the function with blood-activating and qi-promoting
Effect；According to clinical verification, also have the advantages that good effect, safety and stability；
2, the massage cream of freeing vessels and nourishing heart of the invention be using the Chinese medicine composition of freeing vessels and nourishing heart as made of effective component, it is right
Skin is mildly non-stimulated, has no toxic side effect, without drug dependence, is reached by warming meridian, shengjin nourishing, tonifying Qi and lifting yang and promoted blood circulation
The effect of nourishing heart.
Specific embodiment
Below with reference to specific embodiment, the invention will be further described.
Raw material used in following embodiment unless otherwise specified, derives from commercially available.
The Chinese medicine composition of 1 freeing vessels and nourishing heart of embodiment
A kind of Chinese medicine composition of freeing vessels and nourishing heart of the present embodiment is prepared by the raw material extraction of following parts by weight: yellow
5 parts of stilbene, 5 parts of ramulus cinnamomi, 20 parts of radix cyathulae, 30 parts of Snakegourd Fruit, 35 parts of pheretima, 3 parts of Rhizoma Chuanxiong.
The Chinese medicine composition of freeing vessels and nourishing heart described in the present embodiment the preparation method is as follows:
The raw material of above-mentioned parts by weight is weighed, crushes, is placed in extractor, 6 times of the quality that weight is above-mentioned raw materials is added
The EtOH Sonicate that score is 45% extracts 2 times, medical fluid high speed centrifugation, recycles ethyl alcohol and is concentrated into medicinal material: concentrate (1:0.4),
To obtain the final product.
The Chinese medicine composition of 2 freeing vessels and nourishing heart of embodiment
A kind of Chinese medicine composition of freeing vessels and nourishing heart of the present embodiment is prepared by the raw material extraction of following parts by weight: yellow
38 parts of stilbene, 18 parts of ramulus cinnamomi, 1 part of radix cyathulae, 10 parts of Snakegourd Fruit, 15 parts of pheretima, 20 parts of Rhizoma Chuanxiong.
The Chinese medicine composition of freeing vessels and nourishing heart described in the present embodiment the preparation method is as follows:
The raw material for weighing above-mentioned parts by weight is crushed and is sufficiently mixed, is placed in extractor, and it is above-mentioned raw materials that weight, which is added,
The alcohol reflux that 8 times of mass fraction is 55% extracts 1 time, and extract filtration, filter residue adds the second that mass fraction is 15%
Alcohol reflux extracts 1 time, and extract filtration merges filtrate twice, recycles ethyl alcohol and is concentrated into medicinal material: concentrate (1:0.4), i.e.,
?.
The Chinese medicine composition of 3 freeing vessels and nourishing heart of embodiment
A kind of Chinese medicine composition of freeing vessels and nourishing heart of the present embodiment is prepared by the raw material extraction of following parts by weight: yellow
10 parts of stilbene, 7 parts of ramulus cinnamomi, 5 parts of radix cyathulae, 25 parts of Snakegourd Fruit, 28 parts of pheretima, 5 parts of Rhizoma Chuanxiong.
The Chinese medicine composition of freeing vessels and nourishing heart described in the present embodiment the preparation method is as follows:
The raw material for weighing above-mentioned parts by weight, is sufficiently mixed, and smashes into coarse powder, is placed in supersonic extractors, and weight is added and is
The alcohol reflux that 6 times of mass fraction of above-mentioned raw materials is 65% extracts 1 time, and extract filtration, filter residue adds mass fraction
It is extracted 1 time for 15% alcohol reflux, extract filtration merges filtrate twice, recycles ethyl alcohol and is concentrated into medicinal material: concentrate
(1:0.4) to get.
The Chinese medicine composition of 4 freeing vessels and nourishing heart of embodiment
A kind of Chinese medicine composition of freeing vessels and nourishing heart of the present embodiment is prepared by the raw material extraction of following parts by weight: yellow
21 parts of stilbene, 11 parts of ramulus cinnamomi, 11 parts of radix cyathulae, 21 parts of Snakegourd Fruit, 25 parts of pheretima, 11 parts of Rhizoma Chuanxiong.
The Chinese medicine composition of freeing vessels and nourishing heart described in the present embodiment the preparation method is as follows:
The raw material of above-mentioned parts by weight is weighed, is sufficiently crushed, as in extractor, 8 times of medicinal material amounts of above-mentioned raw materials weight are added
65% EtOH Sonicate extract 2 times, extracting solution, low-speed centrifugal is discharged, high speed centrifugation in centrifugate collects centrifugate, merges high
Fast centrifugate, be concentrated under reduced pressure, recycling ethyl alcohol simultaneously be concentrated into medicinal material: concentration amount (1:0.4) to get.
The Chinese medicine composition of 5 freeing vessels and nourishing heart of embodiment
A kind of Chinese medicine composition of freeing vessels and nourishing heart of the present embodiment is prepared by the raw material extraction of following parts by weight: yellow
25 parts of stilbene, 15 parts of ramulus cinnamomi, 15 parts of radix cyathulae, 15 parts of Snakegourd Fruit, 22 parts of pheretima, 15 parts of Rhizoma Chuanxiong.
The Chinese medicine composition of freeing vessels and nourishing heart described in the present embodiment the preparation method is as follows:
The raw material of above-mentioned parts by weight is weighed, crushes, is placed in extractor, the water for 6 times of amounts that weight is above-mentioned raw materials is added
Decoct and extract 2 times, extracting solution filtration, filtrate is concentrated into medicinal material: concentrate (1:0.4) to get.
The massage cream of 6 freeing vessels and nourishing heart of embodiment
A kind of freeing vessels and nourishing heart massage cream of the present embodiment, raw material weight percentage composition are as shown in table 1:
1 freeing vessels and nourishing heart massage cream of table
The massage cream of the freeing vessels and nourishing heart of the present embodiment the preparation method is as follows:
1, each component of B phase is accurately weighed, emulsion pot is added, heating stirring is to 80-90 DEG C, with revolving speed 30r/min
It stirs to substantially uniformity without particle, it is spare；
2, by C phase heating water bath to 90 DEG C, stirring covers 200 mesh filter cloth mistakes to dissolution, insulated sterilizing 30min is completely dispersed
Filter is taken out in emulsion pot, is stirred and is vacuumized homogeneous 2 minutes (maintaining vacuum -0.02~0.05Mpa), until Material becomes complete and homogeneous
Agranular fluid；
3, each component of A phase is accurately weighed, is added in oily phase pot, is heated with stirring to 80-90 DEG C, keep the temperature complete to all components
Fully dissolved, it is spare；
4, under the mixing speed of 30r/min, the component in the oily phase pot of step 3 is crossed into 200 mesh filter clothes and is pumped into step 1
It in emulsion pot, vacuumizes, high speed homogenization 12 minutes (maintaining vacuum -0.02~0.05Mpa), stirring cooling；
5, accurate weighing D phase after mixing, crosses colloid mill, circulation is milled to uniform and smooth pulpous state, spare；
6, the pre-dispersed D to have milled is added to emulsion pot under the mixing speed of 30r/min, vacuumizes high speed homogenization 12
Minute (maintains vacuum -0.02~0.05Mpa), stirring cooling；
7, accurate weighing E phase material is uniformly mixed, is warmed to 45 DEG C to whole dissolutions, spare；
8,48 DEG C are cooled to, pre-dispersed good E phase is added under the mixing speed of 30r/min and enters emulsion pot, component is abundant
Stirring vacuumizes high speed homogenization 32 minutes (maintaining vacuum -0.02~0.05Mpa), makes product complete and homogeneous, stirring cooling；
9, each component of accurate weighing F phase, the lotion to step 8 are cooled to 45 DEG C, and each component of F phase is added, fills
Divide stirring, vacuumize high speed homogenization 3 minutes (maintaining vacuum -0.02~0.05Mpa), make product complete and homogeneous, stirring cooling is dropped
Temperature samples inspection, after qualified, seal lotion, move to semi-finished product storeroom to 37 DEG C of dischargings.
The skin irritation test of the massage cream of 1 freeing vessels and nourishing heart of test example
Skin irritation test is carried out to rabbit using the massage cream of the freeing vessels and nourishing heart of embodiment 6.
One, experimental drug
The massage cream of the freeing vessels and nourishing heart of embodiment 6.
Two, experimental animal
Healthy white experiment is with rabbit totally 20, and (10 are served only for acute skin irritation test, 10 are served only for multiple skin thorn
Swash property test) 2.0~2.5kg of weight.The independent sub-cage rearing of animal during test, standard feed feed, free water with ingest.
Three, experimental method and standards of grading
Acute skin irritation test is with multiple skin irritation test method and step according to " cosmetics health specification
2007 editions " in skin irritation test method and step carry out.Wherein, every rabbit body two sides, this implementation is smeared in side
The freeing vessels and nourishing heart massage cream of example 6 is experimental group, and physiological saline is smeared in side, is blank control group.
Experimental method: before experiment for 24 hours, being lost hair or feathers using 6% sodium sulfide solution, and all tested rabbit backbone two sides are gone
Hair (every side is about 10cm*10cm, should be without erythema, oedema and breakage), every rabbit single cage raising (are raised for 24 hours, observation after depilation
Whether its skin that loses hair or feathers has damage, this experiment is unfit to do if having skin injury).
Standards of grading: according to " herbal pharmacology experimental methodology " with erythema, oedema etc. for evaluation criterion.Standards of grading and thorn
Swash intensity evaluation standard and is shown in Table 2, table 3 respectively.
Four, result
Acute skin irritation test result is as shown in table 4, and the results are shown in Table 5 for multiple skin irritation test.
4 freeing vessels and nourishing heart massage cream of table is to Rabbits with Acute skin irritation test result
The results show that the massage cream as obtained by embodiment 6 and physiological saline test group are administered the tested portion to animal
Position changes without stimulations such as redness, erythema, oedema, and skin irritatin average mean < 0.50 divides, and shows that the two is non-stimulated to skin
Property.
5 freeing vessels and nourishing heart massage cream of table is to the multiple skin irritation test result of rabbit
As can be seen from Table 5, after the freeing vessels and nourishing heart massage cream Yu physiological saline multiple dosing of embodiment 6, test group blank
Control group smears position without the stimulate the reactions such as erythema, pachylosis or epidermatic atrophy, the equal < 0.50 of skin irritatin mean scores
Point, show the two to family's rabbit skin without obvious stimulation.
The stability test of the massage cream of 2 freeing vessels and nourishing heart of test example
The freeing vessels and nourishing heart massage cream of embodiment 6 is stored 30 in the environment of 40 DEG C (heat-resisting) and -10 DEG C (cold-resistant) respectively
It, observes the results show that massage cream without lamination, illustrates that the massage cream stability of freeing vessels and nourishing heart of the present invention is good.
The microorganism of the massage cream of 3 freeing vessels and nourishing heart of test example and sanitary index detection
One, testing goal
Study whether every microorganism and chemical index in the massage cream of freeing vessels and nourishing heart meet relevant criterion.
Two, detection scheme
Massage cream made from embodiment 6 is entrusted into China Guangzhou Analysis &. Test Center, according to " cosmetics health specification
2007 " it is measured.
Three, testing result
Test result such as table 6:
The microorganism of 6 freeing vessels and nourishing heart massage cream of table and sanitary index
As can be known from Table 6, every microorganism and chemical index are qualified in the massage cream of freeing vessels and nourishing heart of the invention.
The clinical trial of 4 freeing vessels and nourishing heart massage cream of test example
One, diagnostic criteria and subject:
Referring to " new Chinese medicine guideline of clinical investigations ": the unexpected pain of in wingceltis and left side chest, characteristic of pain be bored pain,
Distending pain, secret anguish, cusalgia, shouting pain, colic pain can be related to the positions such as throat, shoulder back, gastral cavilty portion.Pain occurs suddenly, when as when stop,
Continue several seconds to several minutes, can be relieved after rest or medication.Often because of the fluctuation of feelings will, climate change, mostly drink gluttony, tired mistake
It spends and induces, can also break out without obvious inducement or when peace and quiet.
Subject: this group 66 presses above-mentioned diagnostic criteria, clarifies a diagnosis through Chinese medicine as chest impediment and cardialgia, wherein male 54
Example, women 12, the age 43-68 years old.Two groups are randomly divided into, every group of 33 people.Selected subject can cooperate well test,
Good daily life system time and eating habit are able to maintain in the trial employment period.
Two, given the test agent, sample application method and time
Test group: the massage cream prepared using embodiment 6.
Application method: twice daily, each 1 time sooner or later.It takes given the test agent to be coated in cave in wingceltis in right amount to massage near left chest
It smears 3-5 minutes.
Comparative example group: Fufang Danshen Pian is taken.
Application method: one time 3,3 times a day.
Three, test the course for the treatment of and clinical detection index
The course for the treatment of on probation is 15 days, is effective with the bored pain of subjects subjective, distending pain, secret anguish, cusalgia, shouting pain, colic pain sense disappearance；
It is on the contrary then invalid.The results are shown in Table 7.
7 freeing vessels and nourishing heart massage cream trial population result of table
As can be known from Table 7, compared with comparative example group (Fufang Danshen Pian), test group (massage cream of embodiment 6) is controlled
Treat it is efficient higher, and the massage cream of test group will not to the irritating effect of human body alimentary canal, safety and stability, have no toxic side effect,
Without drug dependence.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (9)
1. a kind of Chinese medicine external composition of freeing vessels and nourishing heart, which is characterized in that the Chinese medicine composition by following parts by weight original
Material is extracted and is prepared: 5-38 parts of Radix Astragali, 5-18 parts of ramulus cinnamomi, 1-20 parts of radix cyathulae, 10-30 parts of Snakegourd Fruit, 15-35 parts of pheretima, river
3-20 parts of rhizome of chuanxiong.
2. the Chinese medicine external composition of freeing vessels and nourishing heart according to claim 1, which is characterized in that the Chinese medicine composition by
Following parts by weight raw material extraction be prepared: 10-25 parts of Radix Astragali, 7-15 parts of ramulus cinnamomi, 5-15 parts of radix cyathulae, 15-25 parts of Snakegourd Fruit,
22-28 parts of pheretima, 5-15 parts of Rhizoma Chuanxiong.
3. the Chinese medicine external composition of freeing vessels and nourishing heart according to claim 1, which is characterized in that the Chinese medicine composition by
Following parts by weight raw material extraction be prepared: 21 parts of Radix Astragali, 11 parts of ramulus cinnamomi, 11 parts of radix cyathulae, 21 parts of Snakegourd Fruit, 25 parts of pheretima,
11 parts of Rhizoma Chuanxiong.
4. application of the described in any item Chinese medicine external compositions of claims 1 to 3 in the exterior-applied article for preparing freeing vessels and nourishing heart.
5. application according to claim 4, which is characterized in that the exterior-applied article is massage cream.
6. a kind of massage cream of freeing vessels and nourishing heart, which is characterized in that the massage cream is described in any item logical by claims 1 to 3
Common matrix or carrier are prepared in the Chinese medicine composition and cosmetics of arteries and veins nourishing heart.
7. the massage cream of freeing vessels and nourishing heart according to claim 6, which is characterized in that the matrix or carrier include emulsification
Agent, excipient, emollients, conditioner, moisturizer, suspending agent, covering agent, chelating agent, water, preservative and essence.
8. the massage cream of freeing vessels and nourishing heart according to claim 6, which is characterized in that the massage cream is by following weight percent
Several raw materials are prepared: the massage cream is prepared by the raw material of following weight percent: the Chinese traditional medicine composition of freeing vessels and nourishing heart
Object 11-30%, emulsifier 5.3-9.3%, excipient 2.0-6.0%, emollients 10.0-14.0%, conditioner 0.27-
0.67%, moisturizer 11.0-13.0%, suspending agent 0.35%-0.75%, covering agent 0.3-0.7%, chelating agent 0.02-
0.07%, water 38.83-42.83%, preservative 0-1.5%, essence 0-0.4%.
9. the massage cream of freeing vessels and nourishing heart according to claim 8, which is characterized in that the massage cream is by following weight percent
Several raw materials are prepared: Chinese medical extract 20%, stereth -21.8%, the stereth-of freeing vessels and nourishing heart
212.0%, PEG-100 stearate 2.5%, stearine 1.0%, cetostearyl alcohol 4.0%, carbonic acid dioctyl ester
5.0%, isopropyl myristate 5.0%, dimethyl silicone polymer 2.0%, tocopherol acetate 0.1%, bisabolol
0.05%, water 40.83%, 1,3-PD 5.0%, xanthan gum 0.3%, mosanom 0.25%, EDETATE SODIUM 0.05%, beet
Alkali 1.0%, allantoin 0.1%, panthenol 0.2%, titanium dioxide 0.5%, glycerol 5.0%, butanediol 2.0%, tetrahydro piperine
0.02%, methylisothiazolinone/Chlorphenesin 0.6%, Phenoxyethanol/Sensiva SC50 0.5%, essence 0.2%.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1977908A (en) * | 2006-12-20 | 2007-06-13 | 北京润德康医药技术有限公司 | Chinese medicine composition for treating cardio-cerebrovascular disease |
| CN101199651A (en) * | 2006-12-13 | 2008-06-18 | 天津市中宝制药有限公司 | Medicament for treating angina |
| CN102228525A (en) * | 2011-06-27 | 2011-11-02 | 陈伯明 | Traditional Chinese medicine for treating cardio-cerebral vascular stagnation |
| CN103285115A (en) * | 2012-02-22 | 2013-09-11 | 湖南中医药大学 | Preparation method of active components of compound traditional Chinese medicine for treatment of cardiovascular and cerebrovascular ischemic diseases |
-
2015
- 2015-06-16 CN CN201510334997.9A patent/CN104887757B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199651A (en) * | 2006-12-13 | 2008-06-18 | 天津市中宝制药有限公司 | Medicament for treating angina |
| CN1977908A (en) * | 2006-12-20 | 2007-06-13 | 北京润德康医药技术有限公司 | Chinese medicine composition for treating cardio-cerebrovascular disease |
| CN102228525A (en) * | 2011-06-27 | 2011-11-02 | 陈伯明 | Traditional Chinese medicine for treating cardio-cerebral vascular stagnation |
| CN103285115A (en) * | 2012-02-22 | 2013-09-11 | 湖南中医药大学 | Preparation method of active components of compound traditional Chinese medicine for treatment of cardiovascular and cerebrovascular ischemic diseases |
Non-Patent Citations (1)
| Title |
|---|
| 益气化痰祛瘀方对冠心病大鼠纤溶系统的影响;左海宁 等;《河北中医药学报》;20111231;第26卷(第4期);第5页左栏第3段，第6页右栏第3段，第6页左栏第6段 |
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