CN104884055A - 柠檬酸铁在治疗慢性肾脏疾病患者中的应用 - Google Patents

柠檬酸铁在治疗慢性肾脏疾病患者中的应用 Download PDF

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Publication number
CN104884055A
CN104884055A CN201380044271.0A CN201380044271A CN104884055A CN 104884055 A CN104884055 A CN 104884055A CN 201380044271 A CN201380044271 A CN 201380044271A CN 104884055 A CN104884055 A CN 104884055A
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CN
China
Prior art keywords
ferric citrate
iron
patient
mean
ferric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380044271.0A
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English (en)
Chinese (zh)
Inventor
恩里克·普拉多苏
罗恩·本图尔
詹姆斯·F·奥利维耶罗三世
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Keryx Biopharmaceuticals Inc
Original Assignee
Keryx Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Keryx Biopharmaceuticals Inc filed Critical Keryx Biopharmaceuticals Inc
Priority to CN202110644193.4A priority Critical patent/CN113244209A/zh
Publication of CN104884055A publication Critical patent/CN104884055A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201380044271.0A 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用 Pending CN104884055A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110644193.4A CN113244209A (zh) 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261662565P 2012-06-21 2012-06-21
US61/662,565 2012-06-21
US201361757229P 2013-01-28 2013-01-28
US61/757,229 2013-01-28
US201361800618P 2013-03-15 2013-03-15
US201361801050P 2013-03-15 2013-03-15
US61/801,050 2013-03-15
US61/800,618 2013-03-15
PCT/US2013/047134 WO2013192565A2 (en) 2012-06-21 2013-06-21 Use of ferric citrate in the treatment of chronic kidney disease patients

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202110644193.4A Division CN113244209A (zh) 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用

Publications (1)

Publication Number Publication Date
CN104884055A true CN104884055A (zh) 2015-09-02

Family

ID=49769729

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201380044271.0A Pending CN104884055A (zh) 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用
CN202110644193.4A Pending CN113244209A (zh) 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202110644193.4A Pending CN113244209A (zh) 2012-06-21 2013-06-21 柠檬酸铁在治疗慢性肾脏疾病患者中的应用

Country Status (19)

Country Link
US (3) US20130345303A1 (enExample)
EP (3) EP4335436A3 (enExample)
JP (4) JP2015535209A (enExample)
KR (2) KR102150135B1 (enExample)
CN (2) CN104884055A (enExample)
AU (2) AU2013278000A1 (enExample)
BR (1) BR112014032049A2 (enExample)
CA (1) CA2876982A1 (enExample)
DK (1) DK3730136T3 (enExample)
EA (1) EA201590062A1 (enExample)
ES (2) ES2970050T3 (enExample)
FR (1) FR25C1043I1 (enExample)
HK (1) HK1214503A1 (enExample)
IL (1) IL236356A0 (enExample)
MX (1) MX2014015615A (enExample)
NO (1) NO2025048I1 (enExample)
PL (1) PL3730136T3 (enExample)
SG (2) SG11201408521WA (enExample)
WO (1) WO2013192565A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105873583A (zh) * 2013-11-04 2016-08-17 凯克斯生物制药公司 用于降低慢性肾病患者的心力衰竭的枸橼酸铁
CN113613662A (zh) * 2018-10-29 2021-11-05 法码科思莫斯控股有限公司 用羧基麦芽糖铁治疗铁缺乏

Families Citing this family (19)

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CA2768656C (en) 2009-07-21 2016-10-04 Keryx Biopharmaceuticals, Inc. Ferric citrate dosage forms
TWI653043B (zh) * 2012-12-20 2019-03-11 瑞士商伊蘭科動物健康公司 新用途
LT3003327T (lt) 2013-06-05 2017-12-27 Tricida Inc. Protonus surišantys polimerai, skirti geriamajam vartojimui
ES2856261T3 (es) * 2013-10-01 2021-09-27 Fresenius Medical Care Deutschland Gmbh Método y aparatos para determinar una pérdida diaria de hierro de un paciente
WO2015110968A1 (en) * 2014-01-23 2015-07-30 Lupin Limited Pharmaceutical grade ferric citrate and method for its production
WO2015198304A1 (en) 2014-06-22 2015-12-30 Dexcel Pharma Technologies Ltd. Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
CN113855703B (zh) 2014-12-10 2025-11-25 特里赛达公司 用于口服施用的质子结合聚合物
AU2016226250B2 (en) * 2015-03-04 2021-05-27 Keryx Biopharmaceuticals, Inc. Use of ferric citrate in the treatment of iron-deficiency anemia
CN104688706B (zh) * 2015-04-01 2017-07-14 成都欣捷高新技术开发有限公司 一种高载药量、快速溶出的枸橼酸铁组合物及其制备方法
WO2016162794A1 (en) * 2015-04-08 2016-10-13 Leiutis Pharmaceuticals Pvt Ltd Pharmaceutical compositions of ferric citrate
WO2016162888A1 (en) * 2015-04-09 2016-10-13 Actavis Group Ptc Ehf. Process for preparing pharmaceutical grade ferric citrate
WO2017193024A1 (en) 2016-05-06 2017-11-09 Tricida, Inc. Hcl-binding compositions for and method of treating acid-base disorders
US20210085711A1 (en) 2017-09-19 2021-03-25 Japan Tobacco Inc. Use of ferric citrate in prevention and/or treatment of iron-deficiency anemia in hypermenorrhea patient and/or patient suffering from hypermenorrhea-associated gynecologic disease
AU2018360867B2 (en) 2017-11-03 2024-12-12 Tricida, Inc. Compositions for and method of treating acid-base disorders
WO2019236639A1 (en) * 2018-06-04 2019-12-12 Tricida, Inc. Method of treating acid-base disorders
WO2022150623A1 (en) 2021-01-08 2022-07-14 Akebia Therapeutics, Inc. Compounds and composition for the treatment of anemia
WO2022251563A1 (en) 2021-05-27 2022-12-01 Keryx Biopharmaceuticals, Inc. Pediatric formulations of ferric citrate
CN115024495B (zh) * 2022-06-27 2024-03-22 北京金康普食品科技有限公司 改善肾病患者钙磷代谢的营养组合物及其应用
WO2025181559A1 (en) * 2024-02-29 2025-09-04 Sloiron, Inc. Methods for determining the amount of encapsulated and free iron in a sample

Citations (2)

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CN1600302A (zh) * 2003-09-22 2005-03-30 宝龄富锦生技股份有限公司 含有柠檬酸铁的医药组合物以及药用级柠檬酸铁及其制法和含有药用级柠檬酸铁的膳食营养品
CN1751056A (zh) * 2003-02-19 2006-03-22 环亚有限公司 铁有机化合物、其应用及其制备方法

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KR20000067929A (ko) * 1996-07-19 2000-11-25 나가타 코이치 고인혈증 치료제
US5753706A (en) * 1996-12-16 1998-05-19 Hsu; Chen Hsing Methods for treating renal failure
US8093423B2 (en) 2003-02-19 2012-01-10 Globoasia, Llc Pharmaceutical-grade ferric organic compounds, uses thereof and method of making same
US20060134227A1 (en) * 2004-12-22 2006-06-22 Bortz Jonathan D Compositions including iron
MY162727A (en) 2005-08-18 2017-07-14 Panion & Bf Biotech Inc Pharmaceutical-grade ferric organic compounds, uses thereof, and methods of making the same
EP3081219A1 (en) * 2006-01-06 2016-10-19 Luitpold Pharmaceuticals, Inc. Methods and compositions for administration of iron
CN101374416A (zh) * 2006-01-30 2009-02-25 环亚有限公司 逆转、防止、延迟或稳定软组织钙化的方法
CA2768656C (en) * 2009-07-21 2016-10-04 Keryx Biopharmaceuticals, Inc. Ferric citrate dosage forms

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN1751056A (zh) * 2003-02-19 2006-03-22 环亚有限公司 铁有机化合物、其应用及其制备方法
CN1600302A (zh) * 2003-09-22 2005-03-30 宝龄富锦生技股份有限公司 含有柠檬酸铁的医药组合物以及药用级柠檬酸铁及其制法和含有药用级柠檬酸铁的膳食营养品

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105873583A (zh) * 2013-11-04 2016-08-17 凯克斯生物制药公司 用于降低慢性肾病患者的心力衰竭的枸橼酸铁
CN113613662A (zh) * 2018-10-29 2021-11-05 法码科思莫斯控股有限公司 用羧基麦芽糖铁治疗铁缺乏
US11806329B2 (en) 2018-10-29 2023-11-07 Pharmacosmos Holding A/S Treating iron deficiency with ferric carboxymaltose
US12295934B2 (en) 2018-10-29 2025-05-13 Pharmacosmos Holding A/S Treating iron deficiency with ferric carboxymaltose
US12303486B2 (en) 2018-10-29 2025-05-20 Pharmacosmos Holding A/S Treating iron deficiency with ferric carboxymaltose

Also Published As

Publication number Publication date
PL3730136T3 (pl) 2024-03-25
US20150079168A1 (en) 2015-03-19
WO2013192565A2 (en) 2013-12-27
EP4335436A2 (en) 2024-03-13
SG10201805177PA (en) 2018-07-30
JP2020100638A (ja) 2020-07-02
KR20200103855A (ko) 2020-09-02
US20140234416A1 (en) 2014-08-21
ES2796254T3 (es) 2020-11-26
JP2022070945A (ja) 2022-05-13
AU2018203205B2 (en) 2020-03-12
AU2013278000A1 (en) 2015-01-22
HK1214503A1 (zh) 2016-07-29
NO2025048I1 (no) 2025-11-06
KR102150135B1 (ko) 2020-08-31
MX2014015615A (es) 2015-03-20
EP3730136A1 (en) 2020-10-28
CN113244209A (zh) 2021-08-13
US20130345303A1 (en) 2013-12-26
SG11201408521WA (en) 2015-01-29
ES2970050T3 (es) 2024-05-24
CA2876982A1 (en) 2013-12-27
KR20150036131A (ko) 2015-04-07
DK3730136T3 (da) 2024-01-22
EP2863906A2 (en) 2015-04-29
EA201590062A1 (ru) 2016-02-29
WO2013192565A3 (en) 2015-10-15
IL236356A0 (en) 2015-02-26
JP2018138562A (ja) 2018-09-06
EP3730136B1 (en) 2023-12-27
AU2018203205A1 (en) 2018-05-31
EP4335436A3 (en) 2024-05-15
FR25C1043I1 (fr) 2026-01-02
JP2015535209A (ja) 2015-12-10
EP2863906B1 (en) 2020-03-18
HK1210013A1 (en) 2016-04-15
BR112014032049A2 (pt) 2017-07-25

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