CN104873618A - Traditional Chinese medicine preparation for treating eczema - Google Patents

Traditional Chinese medicine preparation for treating eczema Download PDF

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CN104873618A
CN104873618A CN201510317745.5A CN201510317745A CN104873618A CN 104873618 A CN104873618 A CN 104873618A CN 201510317745 A CN201510317745 A CN 201510317745A CN 104873618 A CN104873618 A CN 104873618A
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parts
folium
fine powder
eczema
chinese medicine
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商孝霞
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating eczema and a preparation method thereof. The traditional Chinese medicine preparation is prepared by the following main raw medicinal materials in parts by weight: 10 to 17 parts of cottonrose hibiscus, 7 to 13 parts of hairyfruit croton leaf and root, 9 to 14 parts of radix angelicae lateralis preparata, 10 to 16 parts of sessile alternanthera herb, 8 to 15 parts of faber bauhinia branchlet or root, 9 to 16 parts of bark of Chinese catalpa, 7 to 12 parts of caltrop, 9 to 11 parts of asarum insigne, 8 to 16 parts of common wedgelet fern herb, 10 to 13 parts of clammy hopseedbush leaf, 11 to 16 parts of eastern bracken fern rhizome, 9 to 15 parts of Indian trumpetflower bark, 7 to 11 parts of fried stiff silkworm, 11 to 15 parts of veined rabdosia herb and 9 to 12 parts of greyblue spicebush leaf. The traditional Chinese medicine preparation has the advantages that the safety is high, any toxic and side effect is avoided, the therapy effect is obvious, the restoration of immunity of human body can be effectively adjusted, the self immunity is improved, the sensitivity of the human body to the outside is reduced, the cause of eczema is thoroughly removed, and the reoccurrence of the eczema is effectively prevented.

Description

A kind of Chinese medicine preparation for the treatment of eczema
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine preparation and method for making thereof for the treatment of eczema.
Background technology
Eczema is the inflammatory dermatoses of a kind of common epidermis caused by multiple internal and external factor and high dermis.Its feature is conscious violent pruritus, and skin lesion pleomorphism is symmetrical, has and oozes out tendency, the chronic course of disease, easy recurrent exerbation.Ancient Chinese medicine document is without the name of disease of " eczema ", and according to its Clinical symptoms, Master Home is in the category of " acute eczema ", " noxious dampness ", and according to its site of pathological change is different, title is different again.As being born in crying " ecthyma " of shank, being born in the fossa cubitalis or muscular prominence fossa part " atopic eczema ", being born in scrotum and lower more than ten not planting titles such as " eczema of scrotum ".To the record the earliest of eczema, see Huangdi's Internal Classics.As said in nineteen items of pathogenesis of touching upon in " Plain Questions the most pure virginity will be discussed greatly ": " all sufferings skin ulcers, all belong to the heart." Han dynasty Zhang Zhongjing points out in " Medical Treasures of the Golden Chamber ": " and acute eczema, Rhizoma Coptidis powder master it." first the square medicine of Chinese traditional treatment primary disease is proposed.Afterwards, the understanding of ancient Chinese medicine doctor to primary disease is constantly deepened, as Sui Dynasty Chao Yuanfang (550-630 A.D.) is recorded in " General Treatise on the Cause and Symptoms of Diseases ": " all skin ulcer persons of a specified duration ... by rheumatism is taken advantage of, damp and hotly fight mutually, therefore women's head-ornaments health all gives birth to skin ulcer." explicitly point out wind, wet, heat three is evil is main pathogenic, tentatively established the etiology and pathogenesis basis of primary disease.Ming Dynasty's Chen Shigong supplements improper diet at " Waike Zhengzong, Orthodox Manual of External Diseases ", the cause of disease that interior life is damp and hot, the outer treating method and proposition Pulvis concha Mactrae falls apart.Qing Dynasty Wu Qian describes at Golden Mirror of Medicine: " this disease is nascent as scabies, pruritus without time, spread more than, grab Tianjin yellow fluid, wet in flakes excessive, formed by the heart-fire spleen wind-engaging that wets." not only more detailed describing is done to the clinical symptoms of primary disease, and endogenous cause of ill and exopathogenic factor are organically combined.
Sick just taste lose strong, endogenous dampness, strongly fragrant heat-transformation of a specified duration, retention of damp-heat in the interior, and then rash color is scarlet for outer more skin, contamination flow liquid, and sick recurrent exerbation for a long time, cloudy blood is consumed.Qi-blood disharmony, the raw wind of dryness-transformation, failure of skin and muscle to be nourished, coarse plumpness, touching difficulty more.In a word, this disease belongs to damp and hot, and heat in blood, dampness, caused by blood is dry.1. damp and hot: syndrome: this type is equivalent to acute eczema, skin lesion flushing, vesicle, rotten to the corn, flow liquid, border is filled the air, violent pruritus, accompanies uncomfortable in chest indigestion and loss of appetite, constipation with dry stool, yellowish or reddish urine, yellow, greasy and thin fur, slippery and rapid pulse.Discrimination: 1. dialectical: with erythra flushing, rotten to the corn, ooze out, play is itched as main dialectical main points.2. pathogenesis: damp and hot evil slime flux skin then itch by erythra flushing, erosion, sepage, play.Yellow and greasy fur, slippery and rapid pulse is the disease of damp and hot interior Sheng.Method for the treatment of: clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.2. heat in blood.Syndrome: this type is also equivalent to acute eczema, but sepage is less, skin lesion based on erythema, pimple, scratch, blood crusts, acute pruritus, often with xerostomia red tongue, thready and rapid pulse.Discrimination: 1. dialectical: erythema, pimple, blood crusts, xerostomia, red tongue is dialectical main points.2. pathogenesis: the red-hot folder of heart-fire is wet accumulates skin then show speckle, pimple, blood crusts; The bright body fluid then xerostomia of heat, red tongue.Thready and rapid pulse is resembling of heat in blood.Clearing away heat and cooling blood, helps with dampness removing.3. dampness.Syndrome: mostly be subacute eczema, skin lesion color is dark, light red or not red, and vesicle is few, but liquid water logging is excessive, and often with infantile anorexia, shallow complexion, loose stool is urinated few, and tongue is greasy in vain, and soft pulse is sliding.Discrimination: 1. dialectical: skin lesion color is dark, and vesicle is few, but liquid water logging is excessive, and tongue is greasy in vain, soft pulse is sliding is dialectical main points.2. pathogenesis: dysfunction of the spleen in transportation, endogenous dampness, accumulateing long-pending skin, to cause the water logging of vesicle liquid excessive.Tongue is greasy in vain; The sliding disease for dampness blocking in middle-JIAO of soft pulse.Spleen invigorating dehumidifies, blood-nourishing skin-moisturizing.4. blood is dry.Syndrome: this type is equivalent to chronic eczema, the plump keratinization of skin lesion is broken, or has scratch blood crusts, recurrent exerbation, and the several years does not heal, and often has human body to become thin, pale tongue with white fur, deep-thready pulse or deep and slow.Discrimination: 1. dialectical: skin lesion is plump, and keratinization is broken, prolonged is not more dialectical main points.2. pathogenesis: prolonged illness consumption impairment of YIN blood, wind syndrome due to blood-deficiency dryness-transformation causes skin plumpness, and keratinization is broken.Moderate pulse or heavy be carefully the dry disease of deficiency of YIN blood.Nourish blood dispelling wind, and dehumidifying is moisturized.
Application publication number CN 104398923 A(application number 201410432586.9) Chinese patent literature disclose a kind of Chinese medicine for the treatment of eczema, it is made up of the raw material of following weight proportioning: Radix Scutellariae 6 ~ 12, Cortex Phellodendri 10 ~ 18, Rhizoma Atractylodis 10 ~ 20, Radix Sophorae Flavescentis 12 ~ 23, Herba Plantaginis 15 ~ 25, Rhizoma Smilacis Glabrae 15 ~ 20, Semen Coicis 20 ~ 30, Caulis Akebiae 10 ~ 20, Herba Taraxaci 20 ~ 30, the Radix Rehmanniae 15 ~ 23, the Fructus Kochiae 8 ~ 14.Application publication number CN 104013867 A(application number 201410287998.8) Chinese patent literature disclose a kind of Chinese medicine for the treatment of eczema.It is mainly made up of following Chinese crude drug: Radix Sophorae Flavescentis, Cortex Dictamni, Radix Polygoni Multiflori, Indigo Naturalis, Zaocys, Cortex Phellodendri, the Radix Angelicae Dahuricae, Pollen Typhae, Herba Portulacae, Herba Taraxaci, fresh Rhizoma Phragmitis, Herba Houttuyniae, Semen Coicis, Semen Sinapis Albae, Herba Schizonepetae, Radix Saposhnikoviae, Semen Armeniacae Amarum, Radix Glycyrrhizae.Application publication number CN 102743483 A(application number 201210226204.8) Chinese patent literature disclose a kind of medicine for the treatment of eczema, contained ingredient is formulated by the component of following parts by weight: fine hair hardwood nanmu 6-8 part, true moss 8-10 part, Herba braseniaeel. 10-12 part, Gouania jamnica Miq.[Terminalia kouytchensis Levl. 8-10 part, Radix Saposhnikoviae 6-8 part, Herba Schizonepetae 2-4 part, Cortex Phellodendri 4-6 part, Semen Phaseoli 4-6 part.
For the treatment of eczema, a lot of patient can select western medical treatment.Western medical treatment eczema is based on hormone therapy for oral administration, and long-term taking can produce toxic and side effects, comparatively large to human body infringement, can only eliminate surface inflammation, can not solve morbidity root and the sensitinogen of eczema, be easy to recurrence.The therapy for treating improperly such as employing Western medicine drug, can cause serious harm.Such as, cause subacute or chronic dermatitis eczema, local is in lichen sample pathological changes.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine preparation and method for making thereof for the treatment of eczema.Safety of the present invention is high, have no side effect, evident in efficacy, can effectively regulate immunity of organisms to recover, improve autoimmunity, reduce body for the sensitivity in the external world, remove the cause of disease of eczema thoroughly, effectively prevent eczema rebound phenomenon.
Technical scheme of the present invention is:
Treat a Chinese medicine preparation for eczema, take off the primary raw material medicine stating weight proportion and be prepared from: Hibisci Mutabilis 10-17, Folium Crotonis Laghnocarpi 7-13, Radix Angelicae Sinensis 9-14, Herba Alternantherae sessilis 10-16, Ramulus et Folium Bauhiniae Faberi 8-15, Cortex catalpae ovatae radicis 9-16, Fructus Tribuli 7-12, upper stone Cipangopaludina chinensis 9-11, Folium Stenolomatis 8-16, clammy hopseedbush leaf 10-13, Rhizoma pteridii latiusculi 11-16, Cortex Oroxyli 9-15, Bombyx Batryticatus (parched) 7-11, Herba Rabdosiae Nervosae 11-15, Folium Linderae Glaucae 9-12.
Treat a Chinese medicine preparation for eczema, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Hibisci Mutabilis 12-15, Folium Crotonis Laghnocarpi 9-11, Radix Angelicae Sinensis 11-13, Herba Alternantherae sessilis 12-14, Ramulus et Folium Bauhiniae Faberi 10-13, Cortex catalpae ovatae radicis 11-15, Fructus Tribuli 9-11, upper stone Cipangopaludina chinensis 9.5-10.5, Folium Stenolomatis 10-14, clammy hopseedbush leaf 11-12, Rhizoma pteridii latiusculi 12-14, Cortex Oroxyli 11-14, Bombyx Batryticatus (parched) 8-10, Herba Rabdosiae Nervosae 12-14, Folium Linderae Glaucae 10-11.
Treat a Chinese medicine preparation for eczema, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Hibisci Mutabilis 14, Folium Crotonis Laghnocarpi 10, Radix Angelicae Sinensis 12, Herba Alternantherae sessilis 13, Ramulus et Folium Bauhiniae Faberi 12, Cortex catalpae ovatae radicis 13, Fructus Tribuli 10, upper stone Cipangopaludina chinensis 10, Folium Stenolomatis 12, clammy hopseedbush leaf 11.5, Rhizoma pteridii latiusculi 13, Cortex Oroxyli 12, Bombyx Batryticatus (parched) 9, Herba Rabdosiae Nervosae 13, Folium Linderae Glaucae 10.5.
Present invention also offers the preparation method Chinese medicine preparation of aforementioned therapies eczema being made pharmaceutically acceptable granule, pill, powder and capsule.
The preparation method of described granule is:
(1) Fructus Tribuli is put into boiling water, keep micro-10-15 of boiling minute (preferably keeping micro-boiling 12 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 8-13 minute (preferably frying 11 minutes), taking-up cools, and is ground into fine powder, mistake No. five sieves;
(3) will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are that the soak with ethanol of 30%-70% 1 hour (preferably will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are the soak with ethanol 1 hour of 55%), the amount of ethanol is 5-8 times (amount of preferred alcohol is 7 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, 60 DEG C of heating extraction 2.5-4 hour (preferably 60 DEG C heating extraction 3.5 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34, drying under reduced pressure, be ground into fine powder, cross No. five sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is step (1), the 0.8-1.4 of step (2) and step (3) gained fine powder gross weight doubly (weight of preferably sucrose powder is 1.1 times of step (1), step (2) and step (3) gained fine powder gross weight), mixing, be pressed into thin slice, be ground into granule again, obtain final product.
The preparation method of described pill is:
(1) Fructus Tribuli is put into boiling water, keep micro-10-15 of boiling minute (preferably keeping micro-boiling 12 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. six sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 8-13 minute (preferably frying 11 minutes), taking-up cools, and is ground into fine powder, mistake No. six sieves;
(3) will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are that the soak with ethanol of 30%-70% 1 hour (preferably will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are the soak with ethanol 1 hour of 55%), the amount of ethanol is 5-8 times (amount of preferred alcohol is 7 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, 60 DEG C of heating extraction 2.5-4 hour (preferably 60 DEG C heating extraction 3.5 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34, drying under reduced pressure, be ground into fine powder, cross No. six sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, with water pill, make the pill of the heavy 0.3g of every ball, to obtain final product.
The preparation method of described powder is:
(1) Fructus Tribuli is put into boiling water, keep micro-10-15 of boiling minute (preferably keeping micro-boiling 12 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. eight sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 8-13 minute (preferably frying 11 minutes), taking-up cools, and is ground into fine powder, mistake No. eight sieves;
(3) will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are that the soak with ethanol of 30%-70% 1 hour (preferably will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are the soak with ethanol 1 hour of 55%), the amount of ethanol is 5-8 times (amount of preferred alcohol is 7 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, 60 DEG C of heating extraction 2.5-4 hour (preferably 60 DEG C heating extraction 3.5 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34, drying under reduced pressure, be ground into fine powder, cross No. eight sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, often to wrap 5g subpackage, sterile packaged and get final product.
The preparation method of described capsule is:
(1) Fructus Tribuli is put into boiling water, keep micro-10-15 of boiling minute (preferably keeping micro-boiling 12 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 8-13 minute (preferably frying 11 minutes), taking-up cools, and is ground into fine powder, mistake No. five sieves;
(3) will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are that the soak with ethanol of 30%-70% 1 hour (preferably will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are the soak with ethanol 1 hour of 55%), the amount of ethanol is 5-8 times (amount of preferred alcohol is 7 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, 60 DEG C of heating extraction 2.5-4 hour (preferably 60 DEG C heating extraction 3.5 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34, drying under reduced pressure, be ground into fine powder, cross No. five sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is step (1), the 0.8-1.4 of step (2) and step (3) gained fine powder gross weight doubly (weight of preferably sucrose powder is 1.1 times of step (1), step (2) and step (3) gained fine powder gross weight), mixing, be pressed into thin slice, then be ground into granule, load No. 1 capsule, every capsules is equipped with granule 0.34g, to obtain final product.
Chinese medicine preparation scientific formula provided by the invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience.In addition, excellent results of the present invention also shows:
1, safety high, have no side effect, evident in efficacy;
2, there is the effect of clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, antalgesic-antipruritic, expelling wind and removing dampness, can effectively regulate immunity of organisms to recover, improve autoimmunity, reduce the sensitivity of body for the external world, remove the cause of disease of eczema thoroughly, effectively prevent eczema rebound phenomenon;
3, medicine source is easy to get, and cheap.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1treat a Chinese medicine preparation for eczema, the primary raw material medicine getting following weight parts is prepared from (every part is 400g): Hibisci Mutabilis 10 parts, Folium Crotonis Laghnocarpi 7 parts, Radix Angelicae Sinensis 9 parts, Herba Alternantherae sessilis 10 parts, Ramulus et Folium Bauhiniae Faberi 8 parts, Cortex catalpae ovatae radicis 9 parts, Fructus Tribuli 7 parts, upper stone Cipangopaludina chinensis 9 parts, Folium Stenolomatis 8 parts, clammy hopseedbush leaf 10 parts, Rhizoma pteridii latiusculi 11 parts, Cortex Oroxyli 9 parts, Bombyx Batryticatus (parched) 7 parts, Herba Rabdosiae Nervosae 11 parts, Folium Linderae Glaucae 9 parts.
The preparation method of the Chinese medicine preparation powder of above-mentioned treatment eczema is:
(1) Fructus Tribuli is put into boiling water, keep micro-and boil 10 minutes, take out, dry, grind off hard thorn, be ground into fine powder, cross No. eight sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 8 minutes, taking-up cools, and is ground into fine powder, mistake No. eight sieves;
(3) by all the other the 12 taste crude drug volume fractions except Fructus Tribuli, clammy hopseedbush leaf and Folium Linderae Glaucae be 30% soak with ethanol 1 hour, the amount of ethanol is 5 times of 12 taste crude drug gross weights, 60 DEG C of heating extraction 2.5 hours, extract filtrate, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.31, drying under reduced pressure, be ground into fine powder, cross No. eight sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, often to wrap 5g subpackage, sterile packaged and get final product.
The instructions of taking of the Chinese medicine preparation powder of gained treatment eczema of the present invention is: oral, one day twice, each 5g, boiled water was taken after mixing it with water.
embodiment 2treat a Chinese medicine preparation for eczema, the primary raw material medicine getting following weight parts is prepared from (every part is 400g): Hibisci Mutabilis 17 parts, Folium Crotonis Laghnocarpi 13 parts, Radix Angelicae Sinensis 14 parts, Herba Alternantherae sessilis 16 parts, Ramulus et Folium Bauhiniae Faberi 15 parts, Cortex catalpae ovatae radicis 16 parts, Fructus Tribuli 12 parts, upper stone Cipangopaludina chinensis 11 parts, Folium Stenolomatis 16 parts, clammy hopseedbush leaf 13 parts, Rhizoma pteridii latiusculi 16 parts, Cortex Oroxyli 15 parts, Bombyx Batryticatus (parched) 11 parts, Herba Rabdosiae Nervosae 15 parts, Folium Linderae Glaucae 12 parts.
The preparation method of the Chinese medicine preparation granule of above-mentioned treatment eczema is:
(1) Fructus Tribuli is put into boiling water, keep micro-and boil 12 minutes, take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 11 minutes, taking-up cools, and is ground into fine powder, mistake No. five sieves;
(3) by all the other the 12 taste crude drug volume fractions except Fructus Tribuli, clammy hopseedbush leaf and Folium Linderae Glaucae be 55% soak with ethanol 1 hour, the amount of ethanol is 7 times of 12 taste crude drug gross weights, 60 DEG C of heating extraction 3.5 hours, extract filtrate, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.33, drying under reduced pressure, be ground into fine powder, cross No. five sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is 1.1 times of step (1), step (2) and step (3) gained fine powder gross weight, mixing, be pressed into thin slice, then be ground into granule, to obtain final product.
model case one:king XX, man, 24 years old.Main suit: eczema more than 2 years.Before 2 years there is erythema, pimple in patient hand and upper limb, companion's pruritus.Once diagnosed at local hospital department of dermatologry, be diagnosed as eczema, gave Western medicine oral, had no improvement.On March 19th, 2010 examines.Examine and see that patient hand and upper limb are covered with erythema, pimple, vexed with scratching where it itches, yellow urine, sleeps poor.Be diagnosed as eczema.Take the Chinese medicine preparation granule of the present embodiment gained treatment eczema, three times on the one, each 12g, boiled water is taken after mixing it with water.Take 7 days, pruritus alleviates, and erythema, pimple obviously reduce.Continue to take 7 days, erythema, pimple disappear, and only, all diseases disappear pruritus, cure.Follow up a case by regular visits to without recurrence.
embodiment 3treat a Chinese medicine preparation for eczema, the primary raw material medicine getting following weight parts is prepared from (every part is 400g): Hibisci Mutabilis 12 parts, Folium Crotonis Laghnocarpi 9 parts, Radix Angelicae Sinensis 11 parts, Herba Alternantherae sessilis 12 parts, Ramulus et Folium Bauhiniae Faberi 10 parts, Cortex catalpae ovatae radicis 11 parts, Fructus Tribuli 9 parts, upper stone Cipangopaludina chinensis 9.5 parts, Folium Stenolomatis 10 parts, clammy hopseedbush leaf 11 parts, Rhizoma pteridii latiusculi 12 parts, Cortex Oroxyli 11 parts, Bombyx Batryticatus (parched) 8 parts, Herba Rabdosiae Nervosae 12 parts, Folium Linderae Glaucae 10 parts.
The preparation method of the Chinese medicine preparation pill of above-mentioned treatment eczema is:
(1) Fructus Tribuli is put into boiling water, keep micro-and boil 12 minutes, take out, dry, grind off hard thorn, be ground into fine powder, cross No. six sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 11 minutes, taking-up cools, and is ground into fine powder, mistake No. six sieves;
(3) by all the other the 12 taste crude drug volume fractions except Fructus Tribuli, clammy hopseedbush leaf and Folium Linderae Glaucae be 55% soak with ethanol 1 hour, the amount of ethanol is 7 times of 12 taste crude drug gross weights, 60 DEG C of heating extraction 3.5 hours, extract filtrate, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.33, drying under reduced pressure, be ground into fine powder, cross No. six sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, with water pill, make the pill of the heavy 0.3g of every ball, to obtain final product.
model case two:appoint XX, female, 54 years old.Main suit: both legs eczema more than 2 years, increases the weight of half a year.Before 2 years, occur being dispersed in grain of rice size red papules, have gargalesthesia, gentlier, do not pay attention to after the little shin hard object of patient scratches, both legs eczema area expanded expansion to hand size afterwards, and gargalesthesia is obvious, once scratches, and has and ooze out, and there are hard bits incrustation rear surface.Once Drug therapy was accepted at local hospital, poor effect.On November 4th, 2011 examines.Before patient tells half a year, patient's gargalesthesia increases the weight of, and often scratches, and shank skin lesion face, right side expands, and surperficial redness has oozes out, and itch pain unbearably, night is obvious, does not often independently scratch.Examine and see skin lesion flushing, flow liquid, border is filled the air, violent pruritus, companion's constipation with dry stool, yellowish or reddish urine, yellow, greasy and thin fur, slippery and rapid pulse.Be diagnosed as eczema.Take the Chinese medicine preparation pill of the present embodiment gained treatment eczema, three times on the one, each 10 balls, warm water takes.Take 5 days, red and swollen pruritus obviously alleviates, and skin lesion reduces.Continue to take 1 week, skin lesion disappears, and all diseases disappear, and cures.Follow up a case by regular visits to and have no recurrence.
embodiment 4treat a Chinese medicine preparation for eczema, the primary raw material medicine getting following weight parts is prepared from (every part is 400g): Hibisci Mutabilis 15 parts, Folium Crotonis Laghnocarpi 11 parts, Radix Angelicae Sinensis 13 parts, Herba Alternantherae sessilis 14 parts, Ramulus et Folium Bauhiniae Faberi 13 parts, Cortex catalpae ovatae radicis 15 parts, Fructus Tribuli 11 parts, upper stone Cipangopaludina chinensis 10.5 parts, Folium Stenolomatis 14 parts, clammy hopseedbush leaf 12 parts, Rhizoma pteridii latiusculi 14 parts, Cortex Oroxyli 14 parts, Bombyx Batryticatus (parched) 10 parts, Herba Rabdosiae Nervosae 14 parts, Folium Linderae Glaucae 11 parts.
The preparation method of the Traditional Chinese medicine preparation capsule agent of above-mentioned treatment eczema is:
(1) Fructus Tribuli is put into boiling water, keep micro-and boil 12 minutes, take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 11 minutes, taking-up cools, and is ground into fine powder, mistake No. five sieves;
(3) by all the other the 12 taste crude drug volume fractions except Fructus Tribuli, clammy hopseedbush leaf and Folium Linderae Glaucae be 55% soak with ethanol 1 hour, the amount of ethanol is 7 times of 12 taste crude drug gross weights, 60 DEG C of heating extraction 3.5 hours, extract filtrate, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.33, drying under reduced pressure, be ground into fine powder, cross No. five sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is 1.1 times of step (1), step (2) and step (3) gained fine powder gross weight, mixing, be pressed into thin slice, then be ground into granule, load No. 1 capsule, every capsules is equipped with granule 0.34g, to obtain final product.
model case three:wu XX, female, 30 years old.Main suit: many places skin is red, more than pruritus half a year.Before half a year, there is skin pruritus companion red grouper, pimple without obvious inducement in patient.Once used the Drug therapys such as Compound Flumetasone Ointment, effect does not show.On July 8th, 2009 examines.Examine show mottle, pimple, slightly exceed surface, be dispersed in distribution neck portion, both hands and foot, acute pruritus, with xerostomia red tongue, thready and rapid pulse.Remaining without exception.Be diagnosed as eczema.Take the Traditional Chinese medicine preparation capsule agent of the present embodiment gained treatment eczema, three times on the one, each 3, warm water takes.Take 4 days, skin lesion reduces, and pruritus alleviates.Continue to take 4 days, skin lesion disappears completely, and all diseases disappear, and cures.Follow up a case by regular visits to and have no recurrence.
embodiment 5treat a Chinese medicine preparation for eczema, the primary raw material medicine getting following weight parts is prepared from (every part is 400g): Hibisci Mutabilis 14 parts, Folium Crotonis Laghnocarpi 10 parts, Radix Angelicae Sinensis 12 parts, Herba Alternantherae sessilis 13 parts, Ramulus et Folium Bauhiniae Faberi 12 parts, Cortex catalpae ovatae radicis 13 parts, Fructus Tribuli 10 parts, upper stone Cipangopaludina chinensis 10 parts, Folium Stenolomatis 12 parts, clammy hopseedbush leaf 11.5 parts, Rhizoma pteridii latiusculi 13 parts, Cortex Oroxyli 12 parts, Bombyx Batryticatus (parched) 9 parts, Herba Rabdosiae Nervosae 13 parts, Folium Linderae Glaucae 10.5 parts.
The preparation method of the Chinese medicine preparation powder of above-mentioned treatment eczema is:
(1) Fructus Tribuli is put into boiling water, keep micro-and boil 12 minutes, take out, dry, grind off hard thorn, be ground into fine powder, cross No. eight sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 11 minutes, taking-up cools, and is ground into fine powder, mistake No. eight sieves;
(3) by all the other the 12 taste crude drug volume fractions except Fructus Tribuli, clammy hopseedbush leaf and Folium Linderae Glaucae be 55% soak with ethanol 1 hour, the amount of ethanol is 7 times of 12 taste crude drug gross weights, 60 DEG C of heating extraction 3.5 hours, extract filtrate, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.33, drying under reduced pressure, be ground into fine powder, cross No. eight sieves;
(4) step (1), step (2) and step (3) gained fine powder are mixed, often to wrap 5g subpackage, sterile packaged and get final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Hibisci Mutabilis: base is former: be Malvaceae Hibiscus plant Hibisci Mutabilis, be used as medicine with flower (Flos Hibisci Mutabilis), leaf (Folium Hibisci Mutabilis) and root.The property of medicine: micro-pungent, cool.Function cures mainly: heat-clearing and toxic substances removing, detumescence and apocenosis, cooling blood for hemostasis.For cough due to lung-heat, menorrhagia, leucorrhea; Carbuncle furuncle is controlled in external, mastitis, lymphadenitis, parotitis, burn and scald, venom, traumatic injury.
Folium Crotonis Laghnocarpi: base is former: be leaf, the root of euphorbia plant comospore Fructus Crotonis.The property of medicine: acrid in the mouth; Bitter; Warm in nature; Poisonous.GUIXIN, lung meridian.Function cures mainly: dispelling cold and removing dampness; Expelling wind and activating blood circulation.Main arthralgia due to cold-dampnes, abdominal pain due to blood stasis, puerperal paralysis, treating swelling and pain by traumatic injury, skin pruritus.
Radix Angelicae Sinensis: base is former: the supporting root of umbelliferae angelica.The property of medicine: pungent, sweet, temperature.Function cures mainly: promoting blood circulation and breaking stagnation, menstruction regulating and pain relieving.Control menoxenia, dysmenorrhea, stomachache, traumatic injury, skin infection.
Herba Alternantherae sessilis: base is former: be the herb of amaranthaceous plant Alternanthera sessilis (L.) DC..The property of medicine: sweet, cold.GUIXIN, stomach, small intestine meridian.Function cures mainly: cool the blood dissipate blood stasis, heat-clearing and toxic substances removing, dehumidifies treating stranguria.Main hemoptysis, spit blood, have blood in stool, jaundice due to damp-heat, dysentery, has loose bowels, gingival swelling and pain, laryngopharynx swelling and pain, acute appendicitis, acute mastitis, the cheek of itching, swollen ulcer drug, eczema, stranguria, traumatic injury, venom.
Ramulus et Folium Bauhiniae Faberi: base is former: be branch and leaf or the root of leguminous plant saddle leaf Bauhinia purpurea.The property of medicine: bitter, puckery, flat.Function cures mainly: clearing heat and moistening lung, and yin fluid astringing is calmed the nerves, dehumidifying, parasite killing.Control pertussis, palpitation and insomnia, night sweat is passed out semen, and scrofula is stolen, eczema, scabies.
Cortex catalpae ovatae radicis: base is former: be the root bark of Bignoniaceae plant Chinese catalpa or the phloem of tree.The property of medicine: bitter in the mouth; Cold in nature.Return gallbladder, stomach warp.Function cures mainly: clearing away heat-damp and promoting diuresis, sending down the abnormal ascending QI emesis, killing parasites for relieving itching.Main jaundice due to damp-heat, the inverse vomiting of stomach, skin ulcer scabies, eczema, skin pruritus.
Fructus Tribuli: another name: Fructus Tribuli, Fructus Atriplicis Sibiricae, hard Fructus Tribuli, the dry mature fruit of zygophyllaceae plant Fructus Tribuli.The property of medicine: pungent, bitter, tepor, slightly poisonous.Return Liver Channel.Function cures mainly: suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, and improving eyesight is antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus.
Upper stone Cipangopaludina chinensis: base is former: be the herb of Plants of Polypodiaceae Lemmaphyllum microphyllum presl var. Obovatum (Harr) C Chr.The property of medicine: pungent; Micro-hardship; Cool.Return lung, liver, stomach warp.Function cures mainly: clearing away lung-heat to relieve cough, cooling blood for hemostasis, removing obstruction in the collateral to relieve pain, heat-clearing and toxic substances removing.Main lung abscess, hemoptysis, spits blood, epistaxis, hematuria, stranguria with blood, rheumatalgia, toothache, dysentery, rubella, skin pruritus, malignant boil furuncle, syphilis.
Folium Stenolomatis: base is former: be herb or the rhizome of Lindsaeaceae plant Folium Stenolomatis.The property of medicine: micro-hardship; Cold; Nontoxic.Return liver, lung, large intestine channel.Function cures mainly: heat clearing away, removing toxic substances, dampness removing, hemostasis.Main cold, fever, cough, laryngopharynx swelling and pain, enteritis, dysentery, hepatitis, damp-heat vaginal discharge, carbuncle pyogenic infections from tumour or sore, mumps, aphtha, burn and scald, poisonous snake, lyssodexis, skin eczema, spit blood, hematuria, has blood in stool, traumatic hemorrhage.
Clammy hopseedbush leaf: base is former: be the leaf of sapindaceous plant akeake.The property of medicine: mildly bitter flavor; Pungent; Property is put down.Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Main stranguria, the difficulty in urination, skin pruritus, carbuncle furuncle, burn.
Rhizoma pteridii latiusculi: base is former: be the rhizome of Pteridiaceae plant Herba pteridii latiusculi.The property of medicine: sweet; Cold; Nontoxic.Return lung, liver, spleen, large intestine channel.Function cures mainly: heat clearing away, dampness removing, and suppressing the hyperactive liver is calmed the nerves, removing toxic substances and promoting subsidence of swelling.Main heating, laryngopharynx swelling and pain, diarrhoea, dysentery, jaundice, leucorrhea, hypertension, dizzy insomnia, rheumatic arthralgia, hemorrhoid, proctoptosis, eczema, scalds, snake bite and insect sting.
Cortex Oroxyli: base is former: be the bark of Bignoniaceae plant oroxylum indicum.The property of medicine: mildly bitter flavor; Slightly cool in nature.Function cures mainly: clearing away heat-damp and promoting diuresis, jaundice eliminating, relieving sore throat and diminishing swelling.Main infectious jaundice hepatitis, laryngopharynx swelling and pain.
Bombyx Batryticatus: have another name called Bombyx Batryticatus, flying worm, Bombyx Batryticatus worm, the larva belonging to animal bombyx mori for Bombycidae silkworm infects muscardine and ossified Scorpio.The property of medicine: this product is slightly cylindrical, how bending shrinkage, surperficial lark, matter is hard and crisp, frangibility, acrid in the mouth, salty, and property is put down.Composition: Bombyx Batryticatus containing protein, oxamidic acid., and contains lysine, leucine, aspartic acid etc. 17 seed amino acid.According to modern pharmacological research find, this medical instrument have expelling wind and relieving convulsion, dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat, convulsion, hypoglycemic effect, for apoplexy, migraine and general headache, laryngopharynx swelling and pain, rubella etc.Bombyx Batryticatus (parched) is the processed product of Bombyx Batryticatus.After Bombyx Batryticatus parched with bran, the power of dispelling wind to relieve the exterior syndrome slightly subtracts, and is longer than dissipating phlegm and resolving masses.And Bombyx Batryticatus is after parched with bran, the mycelia on polypide surface and secretions contribute to being removed, and the bad smell that raw meat is salty have also been obtained rectification, are convenient to pulverize, and are convenient to take.In addition, the allergic phenomena indivedual body constitution can also being avoided to take raw product Bombyx Batryticatus cause.
Herba Rabdosiae Nervosae: base is former: be the herb of labiate veined rabdosia herb.The property of medicine: taste is micro-pungent; Bitter; Cold in nature.Function cures mainly: dampness removing stomach function regulating, removing toxic substances sore.Main acute hepatitis, dyspepsia, impetigo, eczema, skin pruritus, burn and scald, venom.
Folium Linderae Glaucae: base is former: be the leaf of canella Fructus Linderae Glaucae.The property of medicine: bitter; Pungent; Cold nature.Return bladder, Liver Channel.Function cures mainly: detoxification and sores, and wind-expelling pain-stopping is antipruritic, hemostasis.Main sore swollen toxin, rheumatic arthralgia, traumatic injury, traumatic hemorrhage, skin pruritus, snake bite and insect sting.
test example 1the clinical practice of the Chinese medicine preparation (embodiment 5) of gained of the present invention treatment eczema: in JIUYUE, 2008 in April ,-2012, screens 314 routine eczema patients in 4 hospitals, wherein male 142 example, women 172 example, age 18-67 year, 38.5 years old mean age, the course of disease 2 months-10 years.Be divided into two groups at random, experimental group and matched group (often organizing 157 examples).Between two groups of patients, the aspect such as sex, age, the state of an illness and course of disease compares, and no significant difference (P > 0.05), has comparability.
Therapeutic Method: experimental group uses gained of the present invention to treat the Chinese medicine preparation of eczema, and using method is: oral, one day twice, each 5g, and boiled water is taken after mixing it with water, and 7 days is a course for the treatment of.Matched group uses the medicine (as Desloratadine dispersible tablet, five dimension Radix Glycyrrhizae those quick capsule, Compound Flumetasone Ointment, Trial of Etofesalamide Ointments etc.) of conventional therapy eczema, within 7 days, is a course for the treatment of.Comparitive study is carried out after two groups of patients all treat two courses for the treatment of.
Curative effect situation criterion: cure: skin lesion disappears completely, subjective symptoms disappears; Effective: skin lesion disappears more than 70%, and subjective symptoms obviously alleviates; Take a turn for the better: skin lesion disappears more than 30%, and subjective symptoms alleviates; Invalid: skin lesion disappears less than 30% or unchanged, and pruritus is without obviously alleviating.Total effectively comprising cures and effective, and result is as shown in table 1.
Table 1: the Chinese medicine preparation compliance test result of gained treatment eczema of the present invention
Efficacy analysis: after two groups of cases treat two courses for the treatment of, experimental group cures 98 examples, effective 56 examples, and take a turn for the better 2 examples, invalid 1 example, total effective rate 98.09%; Matched group cures 30 examples, effective 85 examples, and take a turn for the better 25 examples, invalid 17 examples, total effective rate 73.25%.The cure rate of experimental group and total effective rate are apparently higher than matched group.Test shows, the clinical efficacy of experimental group is obviously better than matched group.
The present invention is primary raw material medicine with Hibisci Mutabilis, Folium Crotonis Laghnocarpi, Radix Angelicae Sinensis and Herba Alternantherae sessilis etc., makes the Chinese medicine preparation for the treatment of eczema.Hibisci Mutabilis heat-clearing and toxic substances removing in side, detumescence and apocenosis, cooling blood for hemostasis.Folium Crotonis Laghnocarpi dispelling cold and removing dampness; Expelling wind and activating blood circulation.Radix Angelicae Sinensis promoting blood circulation and breaking stagnation, menstruction regulating and pain relieving.Herba Alternantherae sessilis cool the blood dissipate blood stasis, heat-clearing and toxic substances removing, dehumidifies treating stranguria.Ramulus et Folium Bauhiniae Faberi clearing heat and moistening lung, yin fluid astringing is calmed the nerves, dehumidifying, parasite killing.Cortex catalpae ovatae radicis clearing away heat-damp and promoting diuresis, sending down the abnormal ascending QI emesis, killing parasites for relieving itching.Fructus Tribuli suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic.Upper stone Cipangopaludina chinensis clearing away lung-heat to relieve cough, cooling blood for hemostasis, removing obstruction in the collateral to relieve pain, heat-clearing and toxic substances removing.Folium Stenolomatis heat clearing away, removing toxic substances, dampness removing, hemostasis.Clammy hopseedbush leaf clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Rhizoma pteridii latiusculi heat clearing away, dampness removing, suppressing the hyperactive liver is calmed the nerves, removing toxic substances and promoting subsidence of swelling.Cortex Oroxyli clearing away heat-damp and promoting diuresis, jaundice eliminating, relieving sore throat and diminishing swelling.Bombyx Batryticatus (parched) dissipating phlegm and resolving masses.Herba Rabdosiae Nervosae dampness removing stomach function regulating, removing toxic substances sore.Folium Linderae Glaucae detoxification and sores, wind-expelling pain-stopping, antipruritic, hemostasis.Many medicines share, and mutually coordinate, play the effects such as clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, antalgesic-antipruritic, expelling wind and removing dampness altogether, can effectively regulate immunity of organisms to recover, improve autoimmunity, reduce the sensitivity of body for the external world, remove the cause of disease of eczema thoroughly, effectively prevent eczema rebound phenomenon.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. treat a Chinese medicine preparation for eczema, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Hibisci Mutabilis 10-17, Folium Crotonis Laghnocarpi 7-13, Radix Angelicae Sinensis 9-14, Herba Alternantherae sessilis 10-16, Ramulus et Folium Bauhiniae Faberi 8-15, Cortex catalpae ovatae radicis 9-16, Fructus Tribuli 7-12, upper stone Cipangopaludina chinensis 9-11, Folium Stenolomatis 8-16, clammy hopseedbush leaf 10-13, Rhizoma pteridii latiusculi 11-16, Cortex Oroxyli 9-15, Bombyx Batryticatus (parched) 7-11, Herba Rabdosiae Nervosae 11-15, Folium Linderae Glaucae 9-12.
2. the Chinese medicine preparation for the treatment of eczema as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Hibisci Mutabilis 12-15, Folium Crotonis Laghnocarpi 9-11, Radix Angelicae Sinensis 11-13, Herba Alternantherae sessilis 12-14, Ramulus et Folium Bauhiniae Faberi 10-13, Cortex catalpae ovatae radicis 11-15, Fructus Tribuli 9-11, upper stone Cipangopaludina chinensis 9.5-10.5, Folium Stenolomatis 10-14, clammy hopseedbush leaf 11-12, Rhizoma pteridii latiusculi 12-14, Cortex Oroxyli 11-14, Bombyx Batryticatus (parched) 8-10, Herba Rabdosiae Nervosae 12-14, Folium Linderae Glaucae 10-11.
3. the Chinese medicine preparation for the treatment of eczema as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Hibisci Mutabilis 14, Folium Crotonis Laghnocarpi 10, Radix Angelicae Sinensis 12, Herba Alternantherae sessilis 13, Ramulus et Folium Bauhiniae Faberi 12, Cortex catalpae ovatae radicis 13, Fructus Tribuli 10, upper stone Cipangopaludina chinensis 10, Folium Stenolomatis 12, clammy hopseedbush leaf 11.5, Rhizoma pteridii latiusculi 13, Cortex Oroxyli 12, Bombyx Batryticatus (parched) 9, Herba Rabdosiae Nervosae 13, Folium Linderae Glaucae 10.5.
4. the Chinese medicine preparation of the treatment eczema as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine preparation of this treatment eczema is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) Fructus Tribuli is put into boiling water, keep micro-10-15 of boiling minute (preferably keeping micro-boiling 12 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 8-13 minute (preferably frying 11 minutes), taking-up cools, and is ground into fine powder, mistake No. five sieves;
(3) will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are that the soak with ethanol of 30%-70% 1 hour (preferably will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are the soak with ethanol 1 hour of 55%), the amount of ethanol is 5-8 times (amount of preferred alcohol is 7 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, 60 DEG C of heating extraction 2.5-4 hour (preferably 60 DEG C heating extraction 3.5 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34, drying under reduced pressure, be ground into fine powder, cross No. five sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is step (1), the 0.8-1.4 of step (2) and step (3) gained fine powder gross weight doubly (weight of preferably sucrose powder is 1.1 times of step (1), step (2) and step (3) gained fine powder gross weight), mixing, be pressed into thin slice, be ground into granule again, obtain final product.
5. the Chinese medicine preparation of the treatment eczema as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine preparation of this treatment eczema is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Fructus Tribuli is put into boiling water, keep micro-10-15 of boiling minute (preferably keeping micro-boiling 12 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. six sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 8-13 minute (preferably frying 11 minutes), taking-up cools, and is ground into fine powder, mistake No. six sieves;
(3) will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are that the soak with ethanol of 30%-70% 1 hour (preferably will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are the soak with ethanol 1 hour of 55%), the amount of ethanol is 5-8 times (amount of preferred alcohol is 7 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, 60 DEG C of heating extraction 2.5-4 hour (preferably 60 DEG C heating extraction 3.5 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34, drying under reduced pressure, be ground into fine powder, cross No. six sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, with water pill, make the pill of the heavy 0.3g of every ball, to obtain final product.
6. the Chinese medicine preparation of the treatment eczema as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine preparation of this treatment eczema is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) Fructus Tribuli is put into boiling water, keep micro-10-15 minute that boils, take out, dry, grind off hard thorn, be ground into fine powder, cross No. eight sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fry 8-13 minute, taking-up cools, and is ground into fine powder, crosses No. eight sieves;
(3) will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are that the soak with ethanol of 30%-70% 1 hour (preferably will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are the soak with ethanol 1 hour of 55%), the amount of ethanol is 5-8 times (amount of preferred alcohol is 7 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, 60 DEG C of heating extraction 2.5-4 hour, extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34, drying under reduced pressure, be ground into fine powder, cross No. eight sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, often to wrap 5g subpackage, sterile packaged and get final product.
7. the Chinese medicine preparation of the treatment eczema as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine preparation of this treatment eczema is made pharmaceutically acceptable capsule, and the preparation method of described capsule is:
(1) Fructus Tribuli is put into boiling water, keep micro-10-15 of boiling minute (preferably keeping micro-boiling 12 minutes), take out, dry, grind off hard thorn, be ground into fine powder, cross No. five sieves;
(2) to pick up the car Folium Mori and Folium Linderae Glaucae, be placed in pot, slow fire heats, and fries 8-13 minute (preferably frying 11 minutes), taking-up cools, and is ground into fine powder, mistake No. five sieves;
(3) will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are that the soak with ethanol of 30%-70% 1 hour (preferably will except Fructus Tribuli, all the other 12 taste crude drug volume fractions outside clammy hopseedbush leaf and Folium Linderae Glaucae are the soak with ethanol 1 hour of 55%), the amount of ethanol is 5-8 times (amount of preferred alcohol is 7 times of 12 taste crude drug gross weights) of 12 taste crude drug gross weights, 60 DEG C of heating extraction 2.5-4 hour (preferably 60 DEG C heating extraction 3.5 hours), extract filtrate, decompression recycling ethanol, be condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.33) that relative density is 1.31-1.34, drying under reduced pressure, be ground into fine powder, cross No. five sieves,
(4) step (1), step (2) and step (3) gained fine powder are mixed, add cane sugar powder, the weight of cane sugar powder is step (1), the 0.8-1.4 of step (2) and step (3) gained fine powder gross weight doubly (weight of preferably sucrose powder is 1.1 times of step (1), step (2) and step (3) gained fine powder gross weight), mixing, be pressed into thin slice, then be ground into granule, load No. 1 capsule, every capsules is equipped with granule 0.34g, to obtain final product.
8. the preparation method of the Chinese medicine preparation powder for the treatment of eczema as claimed in claim 6, is characterized in that, keep micro-boiling 12 minutes in step (1).
9. the preparation method of the Chinese medicine preparation powder for the treatment of eczema as claimed in claim 6, is characterized in that, fry 11 minutes in step (2).
10. the preparation method of the Chinese medicine preparation powder for the treatment of eczema as claimed in claim 6, is characterized in that, 60 DEG C of heating extraction 3.5 hours in step (3).
CN201510317745.5A 2015-06-11 2015-06-11 Traditional Chinese medicine preparation for treating eczema Pending CN104873618A (en)

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Citations (2)

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Publication number Priority date Publication date Assignee Title
CN101032590A (en) * 2007-04-04 2007-09-12 王欣 Chinese medicinal composition to be taken orally for curing eczema
CN103463526A (en) * 2013-09-23 2013-12-25 荣成市科学技术情报研究所 Traditional Chinese medicine composition for treating acute eczema

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101032590A (en) * 2007-04-04 2007-09-12 王欣 Chinese medicinal composition to be taken orally for curing eczema
CN103463526A (en) * 2013-09-23 2013-12-25 荣成市科学技术情报研究所 Traditional Chinese medicine composition for treating acute eczema

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Title
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Application publication date: 20150902