CN104840766A - Traditional Chinese medicine preparation for treating angular cheilitis - Google Patents
Traditional Chinese medicine preparation for treating angular cheilitis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine preparation, and in particular to a traditional Chinese medicine preparation for treating angular cheilitis. The traditional Chinese medicine preparation is made of traditional Chinese medicine raw materials including resurrection plants, dried rehmannia, cynanchum uilfordii helms, orchidaceae dendrobium faulhaberianum, pipal tree seed, houttuynia cordata, lonicera japonica, goldthread, scutellaria baicalensis, cattail leaf fan, toad skin, plantain herb, andrographis paniculata, cortex acanthopanacis and elephantopus scaber. The traditional Chinese medicine preparation has the advantages that used traditional Chinese medicines conform to Chinese pharmacopoeia speculations and are safe, reliable and proper in proportion and have functions of nourishing yin, eliminating fever and the like, and the traditional Chinese medicine preparation is accurate in curative effect, rapid in effect, high in curative ratio, free of side effects and the like.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for the treatment of angular cheilitis.
Background technology
Angular cheilitis is commonly called as " angular chilitis ", show as bicker flushing, blister, chap, erosion, incrustation, desquamation etc.Patient dehisces easily hemorrhage, all effected of speaking of having a meal.The risk factor of angular cheilitis is cold dry weather, and lip, bicker surrounding skin mucosa can be made dry and cracked, and pathogenic bacteria is around taken advantage of a weak point and causes infection; During cheilosis, people can habitually go to lick with tongue, impel angular cheilosis; If the vitamin absorbed from meals reduces, cause vitamin B group in body to lack, also can cause the generation of Vitamin B deficiency angular cheilitis.
Angular cheilitis is initially xerocheilia, bicker place erythema, edema, sepage, incrustation.Local mucosa skin wet when proceeding to chronic, chap, coarse desquamation is with the outside radioactivity wrinkle of bicker.If caused by malnutrition, anemia, riboflavin deficiency, can with oral cavity, tongue and pudendum mucosa lesions, as bright finish tongue, the rubescent and corresponding General Symptoms of skin of scrotum.Many lateral symmetry, also can one-sidedly fall ill.Conscious have burn feeling.Underfed child, can there is pustule in bicker and surrounding thereof, how to infect relevant with pyococcus.Primary disease can be divided into:
1. dystrophic angular cheilitis
Dystrophic angular cheilitis often has generation in malnutrition and vitamin B complex deficient patients, lacks the angular cheilitis caused the most common with vitamin B complex.Show as the wet white of bilateral bicker, rotten to the corn or ulcer, have horizontal ditch to split, notably from bicker to mucosa in mouth or mouth week skin extend, ditch splits the depth, different in size, and pain is not obvious, bicker be everlasting irriate time pain.Normal with xerocheilia, crackle, accidental squama, lip is micro-swollen.Back is level and smooth, and filiform papillae atrophy, the fungiform papillae of edema plumpness is dispersed in distribution, and lingual margin often has indentation.Also often occur together cheilitis, glossitis.
2. coccus angular cheilitis
Coccus angular cheilitis is the angular cheilitis because streptococcus, staphy lococcus infection cause.Be more common in the patient of old anodontia.Show as the wet white of bilateral bicker, rotten to the corn or ulcer, have horizontal crackle, also can suppurate, hemorrhage, incrustation.
3. fungoid angular cheilitis
Fungoid angular cheilitis is because fungus (mainly Candida albicans) infects the angular cheilitis caused.Show as that bilateral bicker is wet white and white is more obvious, have erosion or ulcer, have horizontal crackle, also may have suppuration, hemorrhage, incrustation, the cheilitis that often occurs together and lip rotten to the corn.PAS dyes visible candidiasis mycelia.
At present, treatment angular cheilitis is main mainly with Western medicine, and it is auxiliary for holding concurrently with dietetic therapy and vitamin, but current most of Western medicine is based on antibiotic, brings certain physical impairment to patient.Therefore, that starts with that treatment angular cheilitis becomes at present this disease treatment from traditional Chinese medical science angle probes into direction, the traditional Chinese medical science think the deficiency of YIN scorching be the reason of angular cheilitis, YIN nourishing heat of dispelling becomes the most important thing for the treatment of this disease.
Summary of the invention
According to above the deficiencies in the prior art, the invention provides a kind of Chinese medicine preparation for the treatment of angular cheilitis, it is evident in efficacy, safe and reliable, have no side effect, there is wide potential applicability in clinical practice.
A kind of Chinese medicine preparation for the treatment of angular cheilitis of the present invention, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: demutation grass 20 ~ 30 parts, Radix Rehmanniae 20 ~ 30 parts, Radix cynanchi wilfordii 20 ~ 30 parts, hook Herba Dendrobii 20 ~ 30 parts, bodhi perfume (or spice) 10 ~ 15 parts, Herba Houttuyniae 5 ~ 10 parts, Flos Lonicerae 5 ~ 10 parts, Rhizoma Coptidis 5 ~ 10 parts, Radix Scutellariae 5 ~ 10 parts, flat cattail leaf fan 20 ~ 30 parts, Cutis Bufonis 2 ~ 3 parts, Herba Plantaginis 20 ~ 30 parts, Herba Andrographis 10 ~ 15 parts, Cortex Acanthopancis 10 ~ 15 parts, Elephantopus scaber L. 10 ~ 15 parts.
Wherein, preferred version is as follows:
According to weight parts, be prepared from by following raw material of Chinese medicine: demutation grass 20 parts, Radix Rehmanniae 20 parts, Radix cynanchi wilfordii 20 parts, hook Herba Dendrobii 20 parts, fragrant 10 parts of bodhi, Herba Houttuyniae 5 parts, Flos Lonicerae 5 parts, Rhizoma Coptidis 5 parts, Radix Scutellariae 5 parts, flat cattail leaf fan 20 parts, Cutis Bufonis 2 parts, Herba Plantaginis 20 parts, Herba Andrographis 10 parts, Cortex Acanthopancis 10 parts, Elephantopus scaber L. 10 parts.
Also can be: according to weight parts, be prepared from by following raw material of Chinese medicine: demutation grass 30 parts, Radix Rehmanniae 30 parts, Radix cynanchi wilfordii 30 parts, hook Herba Dendrobii 30 parts, fragrant 15 parts of bodhi, Herba Houttuyniae 10 parts, Flos Lonicerae 10 parts, Rhizoma Coptidis 10 parts, Radix Scutellariae 10 parts, flat cattail leaf fan 30 parts, Cutis Bufonis 3 parts, Herba Plantaginis 30 parts, Herba Andrographis 15 parts, Cortex Acanthopancis 15 parts, Elephantopus scaber L. 15 parts.
Or be: according to weight parts be prepared from by following raw material of Chinese medicine: demutation grass 25 parts, Radix Rehmanniae 25 parts, Radix cynanchi wilfordii 25 parts, hook Herba Dendrobii 25 parts, fragrant 12 parts of bodhi, Herba Houttuyniae 8 parts, Flos Lonicerae 8 parts, Rhizoma Coptidis 8 parts, Radix Scutellariae 8 parts, flat cattail leaf fan 25 parts, Cutis Bufonis 2 parts, Herba Plantaginis 25 parts, Herba Andrographis 12 parts, Cortex Acanthopancis 12 parts, Elephantopus scaber L. 12 parts.
Invention formulation is prepared in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10 ~ 20 minutes, add water again and do not have powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to boiling, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
When taking, each 300ml, one day twice.
Pharmacology analysis:
Demutation grass: light is flat.Diuresis, regulating menstruation, YIN nourishing tonify deficiency.Cure mainly edema, dizzy, tinnitus, infantile malnutrition, menoxenia, stomachache, infantile diarrhea.
Radix Rehmanniae: " herbal classic " so-called Radix Rehmanniae person, namely the dry person of the Radix Rehmanniae also, its method gets Radix Rehmanniae 100 jin, selects fertile person 60 jin, clean, shine and make micro-wrinkle, clean to pick lower person, smash strand juice to the greatest extent in wooden mortar, throw wine and more smash, extracting juice mixes front Radix Rehmanniae, and Japan and China dry or fire dries use.Sweetness and bitterness, cool.Enter the heart, liver, kidney channel.YIN nourishing, nourishes blood.Control fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon hinders constipation.
Radix cynanchi wilfordii: sweetness and bitterness is flat, nontoxic.Return spleen; Stomach; Kidney channel.Invigorating the liver and kidney; Bone and muscle strengthening; Strengthening the spleen and stomach; Removing toxic substances.Main Liver and kidney two is empty; Feel dizzy; Insomnia forgetfulness; Early whitening of beard and hair; Sexual impotence; Seminal emission; The acid of waist knee joint is climbed; Spleen insufficiency; Distension and fullness in the abdomen; Ren is for depressed; Have loose bowels; Puerperal, breast was few; Lymphogranuloma inguinale sore.
Hook Herba Dendrobii: sweet, is slightly cold.Reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.
Bodhi is fragrant: pungent, sweet, flat.Enriching yin and nourishing kidney, suppressing the hyperactive liver improving eyesight, reducing swelling and alleviating pain.Cure cold, dizziness headache, hypertension, anemia, chronic enterogastritis, menoxenia, mastitis, the diseases such as sore.
Herba Houttuyniae: pungent, is slightly cold.Return lung meridian.Heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.For lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.
Flos Lonicerae: sweet, cold.Return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.
Rhizoma Coptidis: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Hot dampness, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Radix Scutellariae: bitter, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Flat cattail leaf fan: bitter, cold.Slightly poisonous.Heat-clearing and toxic substances removing, promoting blood circulation and detumescence.Cure mainly laryngopharynx swelling and pain, tonsillitis, hepatitis, hepatomegaly, stomachache, mastitis.
Cutis Bufonis: pungent, cool, micro-poison.Heat-clearing and toxic substances removing, diuretic relieving distension.Control carbuncle, toxic swelling, scrofula, tumor, infantile malnutrition abdominal distention, chronic tracheitis.
Herba Plantaginis: sweet, cold.Return liver, kidney, lung, small intestine meridian.Clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
Herba Andrographis: bitter, cold.GUIXIN, lung, large intestine, urinary bladder channel.Heat-clearing and toxic substances removing, removing heat from blood, detumescence.For cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, pertussis chronic cough, dysentery, the puckery pain of pyretic stranguria, carbuncle skin infection, venom.
Cortex Acanthopancis: toil is cool.Enter liver, kidney, stomach three warp.Heat-clearing and toxic substances removing, expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation.Cure cold high heat, cough with blood-flecked phlegm, rheumatic arthritis, jaundice, leucorrhea, lithangiuria, traumatic injury, furuncle and phyma skin infection.
Elephantopus scaber L.: bitter, cool.Heat-clearing and toxic substances removing, inducing diuresis to remove edema.For flu, acute tonsillitis, pharyngolaryngitis, eye conjunctivitis, epidemic encephalitis type B, pertussis, acute icterohepatitis, cirrhotic ascites, acute and chronic nephritis, furuncle and phyma, eczema.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and have YIN nourishing and to dispel the effects such as heat, treatment angular cheilitis has that determined curative effect, instant effect, cure rate are high, the feature such as have no side effect.
Outcome measure:
1, case selection: select 100 routine angular cheilitis patients, the range of age was at 8 years old ~ 75 years old, and average 39 years old, wherein, male 58 example, women 42 was routine.
2, diagnostic criteria:
The pathogenic process of angular cheilitis is divided into following 4 phases:
The I phase: bicker epidermis is dry, strip off, start to occur chapping and hemorrhage, surface is covered with serosity;
The II phase: the position consistent with bicker pleat, occur chapping and hemorrhage, surface is covered with serosity;
The III phase: form typical ulcer and form a scab;
The IV phase: decrustation and scarring.
Cure: clinical symptom disappearance; Effective: all diseases are improved; Invalid: all diseases are without improvement.
3, medication: adopt Chinese medicine preparation of the present invention to treat, each 300ml, a day twice.
4, result: cure 96 examples, effective 3 examples, invalid 1 example, total effective rate 99%.
Below enumerate a model case:
1, Song, female, 28 years old.Autumn in 2014, symmetry bilateral bicker district skin one rhagadia mucosa, horizontal, bicker district skin is moistening and in pale asphyxia by saliva, and has pus crusts phenomenon, then to our hospital, is angular cheilitis after diagnosing.First carry out local with sodium bicarbonate gargle to clean, and adopt Chinese medicine preparation of the present invention to treat, each 300ml, one day twice, medication was fully recovered after 4 days, clinical symptom disappearance, followed up a case by regular visits to and did not recur for one month.
Detailed description of the invention
The present invention will be further described by the following examples.
Embodiment 1:
A kind of Chinese medicine preparation for the treatment of angular cheilitis, according to weight parts, be prepared from by following raw material of Chinese medicine: demutation grass 20 parts, Radix Rehmanniae 20 parts, Radix cynanchi wilfordii 20 parts, hook Herba Dendrobii 20 parts, fragrant 10 parts of bodhi, Herba Houttuyniae 5 parts, Flos Lonicerae 5 parts, Rhizoma Coptidis 5 parts, Radix Scutellariae 5 parts, flat cattail leaf fan 20 parts, Cutis Bufonis 2 parts, Herba Plantaginis 20 parts, Herba Andrographis 10 parts, Cortex Acanthopancis 10 parts, Elephantopus scaber L. 10 parts.
Embodiment 2:
A kind of Chinese medicine preparation for the treatment of angular cheilitis, according to weight parts, be prepared from by following raw material of Chinese medicine: demutation grass 30 parts, Radix Rehmanniae 30 parts, Radix cynanchi wilfordii 30 parts, hook Herba Dendrobii 30 parts, fragrant 15 parts of bodhi, Herba Houttuyniae 10 parts, Flos Lonicerae 10 parts, Rhizoma Coptidis 10 parts, Radix Scutellariae 10 parts, flat cattail leaf fan 30 parts, Cutis Bufonis 3 parts, Herba Plantaginis 30 parts, Herba Andrographis 15 parts, Cortex Acanthopancis 15 parts, Elephantopus scaber L. 15 parts.
Embodiment 3:
A kind of Chinese medicine preparation for the treatment of angular cheilitis, according to weight parts, be prepared from by following raw material of Chinese medicine: demutation grass 25 parts, Radix Rehmanniae 25 parts, Radix cynanchi wilfordii 25 parts, hook Herba Dendrobii 25 parts, fragrant 12 parts of bodhi, Herba Houttuyniae 8 parts, Flos Lonicerae 8 parts, Rhizoma Coptidis 8 parts, Radix Scutellariae 8 parts, flat cattail leaf fan 25 parts, Cutis Bufonis 2 parts, Herba Plantaginis 25 parts, Herba Andrographis 12 parts, Cortex Acanthopancis 12 parts, Elephantopus scaber L. 12 parts.
Embodiment 4:
Embodiment 1 ~ embodiment 3 is prepared in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10 ~ 20 minutes, add water again and do not have powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to boiling, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
When taking, each 300ml, one day twice.
Claims (4)
1. treat the Chinese medicine preparation of angular cheilitis for one kind, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: demutation grass 20 ~ 30 parts, Radix Rehmanniae 20 ~ 30 parts, Radix cynanchi wilfordii 20 ~ 30 parts, hook Herba Dendrobii 20 ~ 30 parts, bodhi perfume (or spice) 10 ~ 15 parts, Herba Houttuyniae 5 ~ 10 parts, Flos Lonicerae 5 ~ 10 parts, Rhizoma Coptidis 5 ~ 10 parts, Radix Scutellariae 5 ~ 10 parts, flat cattail leaf fan 20 ~ 30 parts, Cutis Bufonis 2 ~ 3 parts, Herba Plantaginis 20 ~ 30 parts, Herba Andrographis 10 ~ 15 parts, Cortex Acanthopancis 10 ~ 15 parts, Elephantopus scaber L. 10 ~ 15 parts.
2. the Chinese medicine preparation for the treatment of angular cheilitis according to claim 1, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: demutation grass 20 parts, Radix Rehmanniae 20 parts, Radix cynanchi wilfordii 20 parts, hook Herba Dendrobii 20 parts, fragrant 10 parts of bodhi, Herba Houttuyniae 5 parts, Flos Lonicerae 5 parts, Rhizoma Coptidis 5 parts, Radix Scutellariae 5 parts, flat cattail leaf fan 20 parts, Cutis Bufonis 2 parts, Herba Plantaginis 20 parts, Herba Andrographis 10 parts, Cortex Acanthopancis 10 parts, Elephantopus scaber L. 10 parts.
3. the Chinese medicine preparation for the treatment of angular cheilitis according to claim 1, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: demutation grass 30 parts, Radix Rehmanniae 30 parts, Radix cynanchi wilfordii 30 parts, hook Herba Dendrobii 30 parts, fragrant 15 parts of bodhi, Herba Houttuyniae 10 parts, Flos Lonicerae 10 parts, Rhizoma Coptidis 10 parts, Radix Scutellariae 10 parts, flat cattail leaf fan 30 parts, Cutis Bufonis 3 parts, Herba Plantaginis 30 parts, Herba Andrographis 15 parts, Cortex Acanthopancis 15 parts, Elephantopus scaber L. 15 parts.
4. the Chinese medicine preparation for the treatment of angular cheilitis according to claim 1, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: demutation grass 25 parts, Radix Rehmanniae 25 parts, Radix cynanchi wilfordii 25 parts, hook Herba Dendrobii 25 parts, fragrant 12 parts of bodhi, Herba Houttuyniae 8 parts, Flos Lonicerae 8 parts, Rhizoma Coptidis 8 parts, Radix Scutellariae 8 parts, flat cattail leaf fan 25 parts, Cutis Bufonis 2 parts, Herba Plantaginis 25 parts, Herba Andrographis 12 parts, Cortex Acanthopancis 12 parts, Elephantopus scaber L. 12 parts.
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Cited By (1)
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Application publication date: 20150819 |