CN104825674B - A kind of anti-acne antiallergic composition and its preparation method and application - Google Patents
A kind of anti-acne antiallergic composition and its preparation method and application Download PDFInfo
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- CN104825674B CN104825674B CN201410068983.2A CN201410068983A CN104825674B CN 104825674 B CN104825674 B CN 104825674B CN 201410068983 A CN201410068983 A CN 201410068983A CN 104825674 B CN104825674 B CN 104825674B
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Abstract
The present invention provides a kind of anti-acne antiallergic compositions, it is the external preparation being prepared by the bulk pharmaceutical chemicals of following weight proportion: 27-37 parts of dandelion, 15-35 parts of Radix Salviae Miltiorrhizae, 20-47 parts of Kadsura Root-bark, 20-47 parts of viola mandshurica.The present composition, it is good to antiallergic anti-acne activity, reparation cuticula effect is strong, the duration is long, skin allergy can be effectively eliminated, meanwhile, the composition is by each Chinese medicine based on diagnosis and treatment, monarch theory is to instruct reasonable compatibility, each Chinese medicine effect maximization optimizes, and has reached significantly more antiallergic anti-acne, has repaired cuticula activity, provides a kind of new selection for capableing of antiallergic anti-acne, reparation cuticula.
Description
Technical field
The present invention relates to a kind of anti-acne antiallergic compositions and its preparation method and application.
Background technique
The appearance of continuous skin allergic state is because multiple reasons cause cuticula damaged skin under extraneous resistance
Drop, more smegmas that occur together simultaneously are unsmooth and local inflammation is caused to send out as acne.Chinese medicine think skin allergy and acne be by
Caused by insufficiency of the spleen resulting in production of dampness, wet strongly fragrantization heat.
Keratoderma is that the umbrella of skin resistance environmental stimuli makes cuticula using cosmetics excessive wear cutin
The thickness that cannot be kept fit, environmental stimuli, which will directly contact skin, is chronically at it in pessimal stimulation, and skin is caused to support
Drag decline, skin immune function controlling disorder, and occur to continue allergic state.Smegma is unsmooth to cause local inflammation to send out as Cuo
Sore, allergy are often concurrent with acne.
With rapid development of the Chinese herbal medicine in conjunction with modern science and technology research means, the separation of effective component of chinese medicine is identified
Subtleer, pharmacological action is more clear, and medium-height grass the effective elements of the medicine is also widely used in cosmetics.How from Chinese medicine
The effective active constituent for inhibiting acne, repairing damaged Stratum Corneum of middle extraction is research emphasis and direction from now on.
Summary of the invention
The purpose of the present invention is to provide a kind of anti-acne antiallergic compositions and its preparation method and application.
The present invention provides a kind of anti-acne antiallergic composition, it be prepared by the bulk pharmaceutical chemicals of following weight proportion it is outer
With preparation:
27-37 parts of dandelion, 15-35 parts of Radix Salviae Miltiorrhizae, 20-47 parts of Kadsura Root-bark, 20-47 parts of viola mandshurica.
Further, it is the external preparation being prepared by the bulk pharmaceutical chemicals of following weight proportion:
30 parts of dandelion, 28 parts of Radix Salviae Miltiorrhizae, 25 parts of Kadsura Root-bark, 30 parts of viola mandshurica；
Alternatively, public 35 parts of English, 33 parts of Radix Salviae Miltiorrhizae, 31 parts of Kadsura Root-bark, 35 parts of viola mandshurica；
Alternatively, 30 parts of dandelion, 28 parts of Radix Salviae Miltiorrhizae, 25 parts of Kadsura Root-bark, 30 parts of viola mandshurica；
Alternatively, 41 parts of dandelion, 26 parts of Radix Salviae Miltiorrhizae, 29 parts of Kadsura Root-bark, 41 parts of viola mandshurica.
Further, the composition is using the water of each bulk pharmaceutical chemicals or/and ethanol extract as active constituent, in addition pharmacy
Or the preparation for external application to skin that the common auxiliary material of cosmetics or Supplementary active ingredients are prepared.
Further, the concentration of alcohol is 50-80%v/v.
Further, the complementary ingredient is collagen, sodium hyaluronate or vitamin.
Wherein, the external preparation is facial mask, face cream, lotion, gel or toner.
The present invention also provides above-mentioned compositions in preparation treatment acne, antiallergy or/and the external application shield for repairing cuticula
Purposes in skin product or drug.
Further, the acne is acne papulosa, acne pustulosa or cystic acne.
The present composition, good to antiallergic anti-acne activity, reparation cuticula effect is strong, the duration is long, can be effective
Elimination skin allergy, meanwhile, for the composition by each Chinese medicine based on diagnosis and treatment, monarch theory is that guidance is reasonable
Compatibility, each Chinese medicine effect, which maximizes, to be optimized, and has been reached significantly more antiallergic anti-acne, has been repaired cuticula activity, has provided
A kind of new selection for capableing of antiallergic anti-acne, reparation cuticula.
Specific embodiment
The preparation of 1 present composition of embodiment
Dandelion 30g, Radix Salviae Miltiorrhizae 28g, Kadsura Root-bark 25g, viola mandshurica 30g are taken, is crushed, after mixing, adds water to cook 3 times, often
Secondary 1.5h, merging filtrate, concentration, gained medicinal extract, adds suitable quantity of water, glycerol, polyethylene glycol, trehalose, EDTA bis- after drying
Sodium is prepared into facial mask, wherein effective component of chinese medicine content is about 16% with crude drug meter.
The preparation of 2 present composition of embodiment
Dandelion 35g, Radix Salviae Miltiorrhizae 33g, Kadsura Root-bark 31g, viola mandshurica 35g are taken, is crushed, after mixing, adds water to cook 3 times, often
Secondary 1.5h, merging filtrate, concentration, gained medicinal extract after drying add common oil phase auxiliary material, system in suitable quantity of water and external preparation
For at lotion.
The preparation of 3 present composition of embodiment
Dandelion 30g, Radix Salviae Miltiorrhizae 28g, Kadsura Root-bark 25g, viola mandshurica 30g are taken, is crushed, after mixing, 70%v/v ethyl alcohol is added
Refluxing extraction 2 times, each 1h, combined extract, after recycling ethyl alcohol, gained medicinal extract, adds suitable quantity of water and gel base after drying
Matter is prepared into gelling agent.
The preparation of 4 present composition of embodiment
Dandelion 41g, Radix Salviae Miltiorrhizae 26g, Kadsura Root-bark 29g, viola mandshurica 41g are taken, is crushed, after mixing, 60%v/v ethyl alcohol is added
Ultrasonic extraction 3 times, each 15-20min, combined extract, after recycling ethyl alcohol, it is dry after gained medicinal extract, add suitable quantity of water, sweet
Oil and surfactant, are prepared into toner.
Beneficial effects of the present invention are illustrated below by way of clinic.
Therapeutic effect of 1 present composition of test example to allergy
In March, 2013 to July clinic income allergy patient 63, the equal symptom of patient is obvious, and red and swollen scorching hot, veins beneath the skin is expanded
It opens, itch furfur.Applied manufactured facial mask in embodiment 1 after diagnosis is clear, the next day it is primary, one at a time, three Zhou Weiyi
The course for the treatment of.Symptom is recorded after treatment improves statistics effective percentage.Facial mask of the present invention is as shown in table 1 to facial allergy treatment effect.
The effective percentage of 1 antiallergic of table treatment
As can be seen from Table 1, facial mask of the present invention damaged Stratum Corneum after using 1 week is gradually repaired, and allergic symptom is alleviated bright
It is aobvious；Damaged Stratum Corneum is repaired after 3 weeks, and allergic symptom disappears substantially；Effect further repairs impaired angle after 2 courses for the treatment of are used continuously
Matter layer, allergic symptom recurrent exerbation improve.
Therapeutic effect of 2 present composition of test example to acne
In March, 2013 to May clinic income acne patient 82, the equal symptom of patient is typical, wherein papular type 27, warts
31, type, cyst type 24.Applied manufactured facial mask in embodiment 1, the next day it is primary, one at a time, three weeks are as a treatment course.
Symptom is recorded after treatment improves statistics effective percentage.Facial mask of the present invention is as shown in table 2 to facial acne treatment effect.
The validity of 2 anti-acne therapeutic of table
By table 2, it can be seen that, facial mask of the present invention has preferable effect to acne papule type, herpesvirus type, cyst type.Use one
Papule, warts obviously subside after week, and tumour is also relieved；Three type acnes effectively control substantially after three weeks, and skin lesion disappears；Again
Consolidate smegma function through a course for the treatment of to be able to continue adjusting, recurrence reduces.
In conclusion the present composition, good to antiallergic anti-acne activity, reparation cuticula effect is strong, the duration is long,
Skin allergy can be effectively eliminated, meanwhile, by each Chinese medicine based on diagnosis and treatment, monarch theory is the composition
Reasonable compatibility is instructed, each Chinese medicine effect, which maximizes, to be optimized, and it is living to have reached significantly more antiallergic anti-acne, reparation cuticula
Property, provide a kind of new selection for capableing of antiallergic anti-acne, reparation cuticula.
Claims (9)
1. a kind of anti-acne antiallergic composition, it is characterised in that: it is the external application being prepared by the bulk pharmaceutical chemicals of following weight proportion
Preparation:
27-37 parts of dandelion, 15-35 parts of Radix Salviae Miltiorrhizae, 20-47 parts of Kadsura Root-bark, 20-47 parts of viola mandshurica.
2. composition according to claim 1, it is characterised in that: it is prepared by the bulk pharmaceutical chemicals of following weight proportion
External preparation:
30 parts of dandelion, 28 parts of Radix Salviae Miltiorrhizae, 25 parts of Kadsura Root-bark, 30 parts of viola mandshurica；
Alternatively, 35 parts of dandelion, 33 parts of Radix Salviae Miltiorrhizae, 31 parts of Kadsura Root-bark, 35 parts of viola mandshurica；
Alternatively, 30 parts of dandelion, 28 parts of Radix Salviae Miltiorrhizae, 25 parts of Kadsura Root-bark, 30 parts of viola mandshurica.
3. composition according to claim 1, it is characterised in that: the composition is the water or/and second with each bulk pharmaceutical chemicals
Alcohol extracting thing is active constituent, in addition outside the skin that pharmaceutically or cosmetically common auxiliary material or Supplementary active ingredients are prepared
Use preparation.
4. composition according to claim 3, it is characterised in that: the concentration of alcohol is 50-80%v/v.
5. composition according to claim 3, it is characterised in that: the complementary ingredient is collagen, sodium hyaluronate
Or vitamin.
6. composition described in -5 any one according to claim 1, it is characterised in that: the external preparation is facial mask, skin care
Frost, lotion, gel or toner.
7. composition described in claim 1-5 any one is in preparation treatment acne, antiallergy or/and the external application for repairing cuticula
Purposes in skin care item or drug.
8. purposes according to claim 7, it is characterised in that: the acne is acne papulosa, acne pustulosa or capsule
Swollen property acne.
9. a kind of anti-acne antiallergic composition, it is characterised in that: it is the external application being prepared by the bulk pharmaceutical chemicals of following weight proportion
Preparation:
41 parts of dandelion, 26 parts of Radix Salviae Miltiorrhizae, 29 parts of Kadsura Root-bark, 41 parts of viola mandshurica.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410068983.2A CN104825674B (en) | 2014-02-07 | 2014-02-27 | A kind of anti-acne antiallergic composition and its preparation method and application |
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| CN2014100448766 | 2014-02-07 | ||
| CN201410044876 | 2014-02-07 | ||
| CN201410068983.2A CN104825674B (en) | 2014-02-07 | 2014-02-27 | A kind of anti-acne antiallergic composition and its preparation method and application |
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| CN104825674A CN104825674A (en) | 2015-08-12 |
| CN104825674B true CN104825674B (en) | 2019-10-11 |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105078838A (en) * | 2015-09-10 | 2015-11-25 | 柳超 | Acne-removing lotion and preparation method thereof |
| CN105148015A (en) * | 2015-09-21 | 2015-12-16 | 广州环亚化妆品科技有限公司 | Traditional Chinese medicine composition with effect of repairing corneous layer and preparation method and application of traditional Chinese medicine composition |
| CN105310971A (en) * | 2015-10-29 | 2016-02-10 | 桂林华诺威基因药业有限公司 | Acne removing skin care product |
| CN107684572A (en) * | 2017-10-11 | 2018-02-13 | 广州勇达生物科技有限公司 | A kind of anti acne of traditional Chinese medicine composition and preparation method thereof |
| CN108969455B (en) * | 2018-09-04 | 2021-06-22 | 广州鹰远生物科技有限公司 | Acne-removing and moisturizing composition containing herba violae and application of acne-removing and moisturizing composition |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103099904A (en) * | 2013-02-26 | 2013-05-15 | 苏州市洋海电子有限公司 | Traditional Chinese medicine preparation |
| CN103463315A (en) * | 2013-08-23 | 2013-12-25 | 吉林修正药业新药开发有限公司 | Traditional Chinese medicine for treating acne |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103099904A (en) * | 2013-02-26 | 2013-05-15 | 苏州市洋海电子有限公司 | Traditional Chinese medicine preparation |
| CN103463315A (en) * | 2013-08-23 | 2013-12-25 | 吉林修正药业新药开发有限公司 | Traditional Chinese medicine for treating acne |
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