CN104812914B - 诊断受试者中的肝癌的方法及诊断肝癌的试剂盒 - Google Patents

诊断受试者中的肝癌的方法及诊断肝癌的试剂盒 Download PDF

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CN104812914B
CN104812914B CN201380060446.7A CN201380060446A CN104812914B CN 104812914 B CN104812914 B CN 104812914B CN 201380060446 A CN201380060446 A CN 201380060446A CN 104812914 B CN104812914 B CN 104812914B
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gene
marker
liver cancer
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protein
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CN104812914A (zh
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许锦文
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Jinlan Co ltd
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Singapore Health Services Pte Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
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  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201380060446.7A 2012-09-21 2013-09-23 诊断受试者中的肝癌的方法及诊断肝癌的试剂盒 Active CN104812914B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261704425P 2012-09-21 2012-09-21
US61/704,425 2012-09-21
PCT/SG2013/000414 WO2014046623A1 (en) 2012-09-21 2013-09-23 Methods of diagnosing liver cancer in a subject and a kit for diagnosing liver cancer

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CN104812914A CN104812914A (zh) 2015-07-29
CN104812914B true CN104812914B (zh) 2020-07-24

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US (1) US20150232943A1 (enExample)
EP (1) EP2898099A4 (enExample)
JP (1) JP2015530094A (enExample)
KR (1) KR20150058465A (enExample)
CN (1) CN104812914B (enExample)
SG (1) SG11201502089QA (enExample)
WO (1) WO2014046623A1 (enExample)

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KR101843173B1 (ko) * 2014-10-24 2018-03-29 씨비에스바이오사이언스 주식회사 혈관 내피 세포 성장인자 수용체 억제제에 대한 감수성 예측 방법
KR102116178B1 (ko) 2017-05-10 2020-05-27 서울대학교산학협력단 간암 고위험군의 간암 발병 모니터링 또는 진단용 바이오마커 및 그 용도
CN108048422A (zh) * 2017-11-30 2018-05-18 天津市湖滨盘古基因科学发展有限公司 一种gtp酶，imap家族成员7突变蛋白及其应用
CN110241198A (zh) * 2019-05-30 2019-09-17 成都吉诺迈尔生物科技有限公司 一种表征hHRD同源重组缺陷的基因组重组指纹及其鉴定方法
CN111610262A (zh) * 2020-05-19 2020-09-01 上海鹿明生物科技有限公司 一种用于肝胆疾病诊断的代谢标志物
WO2025111814A1 (zh) * 2023-11-28 2025-06-05 何牮 一种b细胞的生物标志物组及其应用

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2007063118A1 (en) * 2005-11-30 2007-06-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for hepatocellular carcinoma classificastion and prognosis

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AU2003214604A1 (en) * 2002-03-21 2003-10-08 Hadasit Medical Research Services And Development Ltd. Peripheral blood cell markers useful for diagnosing multiple sclerosis and methods and kits utilizing same
WO2005043163A2 (en) * 2003-11-04 2005-05-12 Roche Diagnostics Gmbh Method for distinguishing who classified aml subtypes
WO2008138578A2 (en) * 2007-05-11 2008-11-20 Medical Prognosis Institute Methods, kits, and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
EP2352847B1 (en) * 2008-11-10 2014-01-08 The United States of America, as represented by The Secretary, Department of Health and Human Services Gene signature for predicting prognosis of patients with solid tumors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007063118A1 (en) * 2005-11-30 2007-06-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for hepatocellular carcinoma classificastion and prognosis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells.;ASTILLO, J. 等;《CANCER RESEARCH》;20060615;第66卷;6129-6138 *
Identification of novel tumor markers in hepatitis C virus- associated hepatocellular carcinoma;SMITH, M.W.等;《CANCER RESEARCH》;20030215;第63卷;859-864 *
SMITH, M.W.等.Identification of novel tumor markers in hepatitis C virus- associated hepatocellular carcinoma.《CANCER RESEARCH》.2003,第63卷859-864. *

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Publication number Publication date
EP2898099A4 (en) 2016-05-25
KR20150058465A (ko) 2015-05-28
WO2014046623A1 (en) 2014-03-27
CN104812914A (zh) 2015-07-29
SG11201502089QA (en) 2015-06-29
EP2898099A1 (en) 2015-07-29
US20150232943A1 (en) 2015-08-20
JP2015530094A (ja) 2015-10-15

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