CN104686793A - Chinese herbal medicine compound feed additive for preventing ophicephalus argus skin canker disease - Google Patents

Chinese herbal medicine compound feed additive for preventing ophicephalus argus skin canker disease Download PDF

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Publication number
CN104686793A
CN104686793A CN201510126507.6A CN201510126507A CN104686793A CN 104686793 A CN104686793 A CN 104686793A CN 201510126507 A CN201510126507 A CN 201510126507A CN 104686793 A CN104686793 A CN 104686793A
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parts
chinese herbal
feed additive
skin
snakehead
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CN201510126507.6A
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CN104686793B (en
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黄锦炉
张凤娴
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GUANGDONG HAID GROUP Co.,Ltd.
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QINGYUAN HAIBEI BIOLOGICAL TECHNOLOGY Co Ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish
    • Y02A40/818Alternative feeds for fish, e.g. in aquacultures

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  • Medicines Containing Plant Substances (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A Chinese herbal medicine compound feed additive for preventing the ophicephalus argus skin canker disease comprises, by weight, 10-14 parts of humifuse euphorbia herb, 20-25 parts of cortex phellodendri, 12-16 parts of angelica sinensis, 5-8 parts of illicium verum, 8-15 parts of puerarin, 10-12 parts of flower of poplar and 25-35 parts of composite multi-element. The Chinese herbal medicine compound feed additive can effectively prevent the ophicephalus argus skin canker disease.

Description

A kind of Chinese herbal composite feed additive preventing snakehead skin-ulcer
Technical field
The present invention relates to feed additive field, more specifically, relate to a kind of Chinese herbal composite feed additive preventing snakehead skin-ulcer.
Background technology
Snakehead, is commonly called as snakeheaded fish, and in China, cultivation is distributed more widely, has the features such as growth is fast, disease is few, strong adaptability, has become one of Variety comprehensive of fresh water famous-particular-excellent cultivation.
Along with raising and the popularization of snakehead intensive culture technology, snakehead per mu yield can reach 20,000 jin, and be about 10 times of four large Chinese carp per mu yields, fanning economics is very considerable.But during two ages, snakehead cultivated the 5-8 month then, coerce the impact with the factor such as pathogenic infection by breeding environment, cultivation snakehead skin-ulcer occurs again and again, and the incidence of disease is 10-40%, and general snakehead starts dead after morbidity in 10-15 days.On disease symptom, main manifestations is that epidermal mucus increases, and the local patholoic change of not specific modality appears in body surface not privileged site, and the skin surface being evolved into the stove that festers necroses, comes off, lower layers of skin muscle fibre oedema, fracture, dissolving; Stove surrounding tissue of festering is many with congested and petechial hemorrhage; When being in a bad way, snakehead anus is red and swollen, time have yellow mucus to flow out, be stained with yellow mucus in stomach, enteron aisle, intestinal mucosa is thinning, the functioning cell generation inflammatory necrosis that the gill, liver, kidney etc. are organized.
Facts have proved, snakehead skin-ulcer there is obvious seasonality, but the timing node of morbidity has uncertainty, therefore the prevention focusing on disease popularity season is only had, the large area of effective this disease of prevention and control of ability occurs and diffusion, avoids the continuous worsening serious financial consequences caused because of the state of an illness to greatest extent.As can be seen here, how to prevent just to become key point.
Summary of the invention
For above-mentioned deficiency, the object of the invention is to provide a kind of for preventing snakehead skin-ulcer Chinese herbal composite feed additive, for preventing snakehead in the generation of disease popularity skin-ulcer in season.
First the present invention provides a kind of Chinese herbal composite feed additive preventing snakehead skin-ulcer, by weight, following component is comprised: wolf's milk 10-14 part, golden cypress 20-25 part, Radix Angelicae Sinensis 12-16 part, Chinese anise 5-8 part, root of kudzu vine 8-15 part, poplar flower 10-12 part, compound vitamin 25-35 part.
Described compound vitamin, by weight, comprises following component: vitamin C phosphoric ester 40 parts, vitamin B1 8 parts, vitamin B2 8 parts, vitamin B5 8 parts, vitamin B6 5 parts, vitamin B12 12 parts, vitamin D 4 parts, vitamin E phosphate 15 parts.
Described component also crosses 300 order net process through ultramicro grinding.
The above-mentioned application of Chinese herbal composite feed additive in preparation prevention snakehead skin-ulcer medicine is further provided.
The addition of described Chinese herbal composite feed additive is 0.4 ~ 0.6% of quality of the fodder.
The invention has the advantages that
1. six kinds of Chinese herbal medicine compatibilities are reasonable, after the ultramicro grinding technique preparation of advanced person, herbal component active ingredient is discharged greatly, is conducive to promoting the absorption of Chinese herbal medicine in snakehead body, distribution, metabolism and excretion, guarantees that expection effect of herbal component obtains good expression.
2. on the basis of Chinese herbal medicine compatibility, prescription is aided with vitamin C, Cobastab, vitamin D and vitamin E again, the ability to express of snakehead body surface immune factor can be strengthened, promote that body surface blood circulation is unimpeded, improve snakehead environment resistant stress ability, strengthen snake-head immunity level.
3. each Component Source of Chinese herbal composite feed additive enriches, and cheap, noresidue nontoxic to environment, does not cause cause of disease drug resistance to produce yet, and belongs to environment protection type functional type feed addictive category.
Detailed description of the invention
The present invention is further described below in conjunction with specific embodiment.Unless stated otherwise, the present invention adopts reagent, equipment and method are conventional commercial reagent, equipment and the conventional method used of the art.
Embodiment 1
A kind of prevention snakehead skin-ulcer Chinese herbal composite feed additive, preferred formula is, by weight, comprise following component, wolf's milk 10 parts, golden cypress 20 parts, Radix Angelicae Sinensis 15 parts, Chinese anise 5 parts, the root of kudzu vine 10 parts, poplar flower 10 parts, compound vitamin 30 parts.
Each raw material is pulverized through micronizer, crosses 300 object screen clothes, mix, then add in compound feed for snakeheads using according to mass percent 0.4% to.
Feed based on commercially available common Snakeheaded fish feeding stuff, test group throws something and feeds 20 days continuously containing Chinese herbal composite feed additive Snakeheaded fish feeding stuff, then moves on to and feeds 10 days common Snakeheaded fish feeding stuffs, and control group continuous 30 days common Snakeheaded fish feeding stuffs of throwing something and feeding.When test the 30th day, gather snakehead epidermal mucus sample, test group and control group snakehead epidermal mucus antibacterial activity and lysozyme activity are measured.
Upper table data show, to throw something and feed continuously the Snakeheaded fish feeding stuff of interpolation 0.4% Chinese herbal composite feed additive, snakehead epidermal mucus bacteriostasis rate to be thrown something and fed group apparently higher than commercially available Snakeheaded fish feeding stuff, and epidermal mucus minimal inhibitory concentration (with mucus protein content meter) is starkly lower than commercial diet and throws something and feeds group.This illustrates the antibacterial activity adopting the present embodiment can significantly improve snakehead epidermal mucus bacteriostasis rate and mucus effective active composition.
Group Lysozyme activity (mg/L)
Containing the Snakeheaded fish feeding stuff group of Chinese herbal composite feed additive group 645
Commercially available Snakeheaded fish feeding stuff group 319
Upper table data show, the Snakeheaded fish feeding stuff of interpolation 0.4% Chinese herbal composite feed additive of throwing something and feeding continuously, and snakehead body surface dark bacterium enzymatic activity to be thrown something and fed group apparently higher than commercially available Snakeheaded fish feeding stuff.This illustrates the expression and secretion adopting the present embodiment obviously can strengthen snakehead epidermal mucus lysozyme.
Embodiment 2
A kind of prevention snakehead skin-ulcer Chinese herbal composite feed additive, preferred formula is, by weight, comprise following component, wolf's milk 12 parts, golden cypress 20 parts, Radix Angelicae Sinensis 12 parts, Chinese anise 5 parts, the root of kudzu vine 8 parts, poplar flower 13 parts, compound vitamin 30 parts.
Each raw material is pulverized through micronizer, crosses 300 object screen clothes, mix, then add in compound feed for snakeheads using according to mass percent 0.6% to.
Feed based on commercially available common Snakeheaded fish feeding stuff, test group throws something and feeds 20 days continuously containing Chinese herbal composite feed additive Snakeheaded fish feeding stuff, then moves on to and feeds 10 days common Snakeheaded fish feeding stuffs, is one prevents the course for the treatment of with 30 days.Feeding method according to this, throws something and feeds the 2-3 course for the treatment of continuously to test group snakehead.Duration of test, control group snakehead continues commercially available common Snakeheaded fish feeding stuff of throwing something and feeding.Record test group and control group snakehead skin-ulcer morbidity quantity and dead quantity simultaneously.Prevent terminate latter 10 days the course for the treatment of, comparative analysis test group and contrast snakehead skin-ulcer M & M.
Group The incidence of disease (%) The death rate (%)
Containing the Snakeheaded fish feeding stuff group of Chinese herbal composite feed additive group 5.2 1
Commercially available Snakeheaded fish feeding stuff group 14.7 6.6
Upper table data show, by the prevention using method course for the treatment of, and the Snakeheaded fish feeding stuff of interpolation 0.6% Chinese herbal composite feed additive of throwing something and feeding continuously, the M & M of snakehead skin-ulcer during can disease popularity being effectively reduced.This illustrates the M & M adopting the present embodiment can effectively reduce snakehead skin-ulcer, has a significant effect to prevention snakehead skin-ulcer, is conducive to significantly improving snakehead cultivation success rate, increases fanning economics.

Claims (5)

1. one kind is prevented the Chinese herbal composite feed additive of snakehead skin-ulcer, it is characterized in that, by weight, following component is comprised: wolf's milk 10-14 part, golden cypress 20-25 part, Radix Angelicae Sinensis 12-16 part, Chinese anise 5-8 part, root of kudzu vine 8-15 part, poplar flower 10-12 part, compound vitamin 25-35 part.
2. prevention snakehead skin-ulcer Chinese herbal composite feed additive according to claim 1, is characterized in that, described compound vitamin, by weight, comprises following component: vitamin C phosphoric ester 40 parts, Cobastab 18 parts, Cobastab 28 parts, Cobastab 58 parts, Cobastab 65 parts, Cobastab 1212 parts, vitamin D 4 parts, vitamin E phosphate 15 parts.
3. prevention snakehead skin-ulcer Chinese herbal composite feed additive according to claim 1, is characterized in that, described component also crosses 300 order net process through ultramicro grinding.
4. the application of Chinese herbal composite feed additive according to claim 1 in preparation prevention snakehead skin-ulcer medicine.
5. application according to claim 4, is characterized in that, the addition of described Chinese herbal composite feed additive is 0.4 ~ 0.6% of quality of the fodder.
CN201510126507.6A 2015-03-20 2015-03-20 A kind of Chinese herbal composite feed additive for preventing snakehead skin-ulcer Active CN104686793B (en)

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CN105920474A (en) * 2016-04-21 2016-09-07 固镇玉鹏生态农业文化园有限公司 Snakehead fish fry protective liquid
CN112655844A (en) * 2020-12-22 2021-04-16 广东溢多利生物科技股份有限公司 Compound preparation for improving immunity of snakeheads as well as preparation method and application of compound preparation

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105920474A (en) * 2016-04-21 2016-09-07 固镇玉鹏生态农业文化园有限公司 Snakehead fish fry protective liquid
CN112655844A (en) * 2020-12-22 2021-04-16 广东溢多利生物科技股份有限公司 Compound preparation for improving immunity of snakeheads as well as preparation method and application of compound preparation

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Effective date of registration: 20200601

Address after: 511400 Huambo four road, Panyu District, Guangzhou, Guangdong 42 No. 2 701

Patentee after: GUANGDONG HAID GROUP Co.,Ltd.

Address before: The town of Taiping District Forest Farm in Guangdong province 511853 fresh heart of Qingyuan City

Patentee before: QINGYUAN HAIBEI BIOLOGICAL TECHNOLOGY Co.,Ltd.