CN104642363A - A composite pesticidal composition comprising metaflumizone and spinetoram and applications thereof - Google Patents
A composite pesticidal composition comprising metaflumizone and spinetoram and applications thereof Download PDFInfo
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- CN104642363A CN104642363A CN201310580872.5A CN201310580872A CN104642363A CN 104642363 A CN104642363 A CN 104642363A CN 201310580872 A CN201310580872 A CN 201310580872A CN 104642363 A CN104642363 A CN 104642363A
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- metaflumizone
- ethyl pleocidin
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Abstract
A composite pesticidal composition comprising metaflumizone and spinetoram and uses thereof are disclosed. The composition adopts the metaflumizone and the spinetoram as pesticidal active components, wherein the weight ratio of the metaflumizone to the spinetoram being 0.1-80:0.5-80. The composition can generate a high synergistic interaction, overcomes and delays pest resistance to pesticides, is high in pest killing speed, long in duration of efficacy, and reduced in pesticide using cost, and has control effects obviously higher than effects when a single pesticide is used. The composition can control lepidoptera pests on crops, especially can control cotton bollworm and stem borers, and has effects obviously higher than the effects when a single pesticide is used.
Description
Technical field
The invention belongs to the field of agricultural pesticide containing heterocyclic compound, be specifically related to a kind of Pesticidal combination and the application thereof that contain metaflumizone and ethyl pleocidin.
Background technology
Metaflumizone (metaflumizone), chemical name is: (E+Z)-2-[2-(4-cyano group benzene)-1-(3-trifluoromethylbenzene) ethylidene]-N-(4-trifluomethoxybenzene) hydrazine carbonyl oxamides.Structural formula is:
Metaflumizone (metaflumizone, BAS320I) is a kind of brand-new compound that BASF Aktiengesellschaft and Japanese agricultural chemicals company develop jointly, and belongs to semicarbazones insecticides.The mechanism of action of metaflumizone is unique, and itself has insecticidal activity, does not need bioactivation, with existing each insecticides without cross resistance.Metaflumizone can prevent and treat larva, the adult of various places lepidoptera pest and some coleoptera effectively, can also be used for preventing and treating the insects such as ant, termite, fly class, cicada dung beetle.
Ethyl pleocidin (Spinetoram), structural formula is:
XDE-175-J is the novel pleocidin insecticides of one of being produced by Dow AgroSciences, and receive first whole world registration, it effectively can control the important insect pest on fruit tree and nut, a kind of thorny primary pest especially on fruit tree---the stupid moth of apple.Be mainly used in control lepidopterous larvae, thrips and Liriomyza etc., to the control efficiency that diamond-back moth, beet armyworm, Liriomyza, thrips, prodenia litura, lima bean pod borer have had.
Containing the insecticide variety of single component often existing defects in agricultural chemicals control of insect: use is easily developed immunity to drugs continuously, and insecticidal spectrum is narrow, and can not provide comprehensive protection for crop, peasant's drug cost is high.To a certain extent can the above-mentioned shortcoming of customer service by two kinds or being combined in of two or more active component.There is two kinds of synergistic effect or the combination mixture of two or more active component, can preventive effect be improved, reduce active ingredient ground dosage, cost-saving, slow down pest resistance and to occur and can expanding prevention spectrum, play that many worms are double to be controlled, reduce the use cost of peasant.
Summary of the invention
The object of this invention is to provide a kind of Pesticidal combination containing metaflumizone and ethyl pleocidin, this Pesticidal combination is the multifunctional insecticide composition of control lepidoptera pest.
Another object of the present invention is to provide this Pesticidal combination and is preparing the application prevented and treated on the insecticidal materials of resistance lepidoptera pest, the application particularly on the insecticidal materials preparing control cotton bollworm or snout moth's larva.
The object of the invention is to be achieved through the following technical solutions:
Containing a Pesticidal combination for metaflumizone and ethyl pleocidin, this Pesticidal combination is with metaflumizone and ethyl pleocidin for principle active component, and wherein, the weight ratio of metaflumizone and ethyl pleocidin is 0.1 ~ 80:0.5 ~ 80.
In Pesticidal combination of the present invention, the weight ratio of metaflumizone (A) and ethyl pleocidin (B) is preferably 0.5 ~ 50:1 ~ 50, and more preferably 1 ~ 17:1 ~ 20, most preferably are 1 ~ 10:1; The another kind of preferably weight ratio that scheme is both A and B is 0.1 ~ 20:1, more preferably 0.1 ~ 10:1.
This Pesticidal combination only containing active component metaflumizone and ethyl pleocidin, also can add other components when using or prepare in active component.
In Pesticidal combination of the present invention, both metaflumizone and the ethyl pleocidin weight percentage in this Pesticidal combination is 3% ~ 80%, is preferably 5% ~ 55%, most preferably 10% ~ 40%.
Pesticidal combination of the present invention with metaflumizone and ethyl pleocidin for active component or principle active component, any one formulation that agricultural chemicals allows is become, the preferred missible oil of described formulation, suspending agent, wetting powder, aqueous emulsion, microemulsion or water dispersion granule with insecticides adjuvant and excipient.
Aforementionedly can be applicable to the not special restriction of insecticides adjuvant of the present invention, include, but are not limited to calcium dodecyl benzene sulfonate, 600#, the rare block copolymer of polyoxyethylene polyoxy third (as agriculture breast 33#), polyoxyethylene nonylphenol ether etc., aforementionedly can be applicable to excipient of the present invention and be also not particularly limited, include, but are not limited to solvent naphtha, water, antifreezing agent (as propane diols), deionized water etc.Above auxiliary agent, excipient and other auxiliary material can be alone or and use.
Pesticidal combination of the present invention has good preventive effect to the multiple Semiptera of the easy generation such as rice fulgorid and snout moth's larva resistance and lepidoptera pest; And suppress insect to produce the pesticide resistance of unitary agent (metaflumizone or ethyl pleocidin arbitrary).
Pesticidal combination of the present invention is preparing the application prevented and treated on resistance lepidoptera pest insecticidal materials, and the effect especially on preparation control cotton bollworm or snout moth's larva insecticidal materials is remarkable.
Compared with prior art beneficial effect of the present invention: (1) is compared with single dose, said composition antagonism lepidoptera pest is obvious synergistic function as cotton bollworm, snout moth's larva etc. have, and overcomes and has delayed pest resistance to insecticide, and expanding prevention is composed, desinsection speed is fast, significantly improves control efficiency; (2) control recruitment, drug cost is reduced; (3) alternative high-toxic pesticide; (4) have concurrently quick-acting and long-acting; (5) with metaflumizone compared with ethyl pleocidin single dose, produce and use cost reduction; (6) suppress lepidoptera pest to strengthen the resistance of agricultural chemicals, its successful uses higher than its single dose.
Embodiment
Below in conjunction with embodiment, the invention will be further described, but do not limit the present invention in any way.
Embodiment 1:
Take metaflumizone and ethyl pleocidin altogether 30g, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 4g, vegetable oil to 100g.The method above raw material being prepared routinely missible oil drops in mixing kettle and mixes, and is mixed with the metaflumizone ethyl pleocidin missible oil that principle active component weight percentage is 30%.Wherein the concrete ratio of metaflumizone and ethyl pleocidin is in table 1 and 2.
Adopt feed to add malicious method and carry out indoor synergy biologicall test, selection resistant bollworm is target pest, and often process repetition 3 times, every concentration process 60, calculates toxicity regression equation and the lethal concentration of 50 LC of each medicament antagonism cotton bollworm by probability value method
50, use LC
50value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient, the results are shown in Table 1:
Table 1 metaflumizone and ethyl pleocidin is composite and the toxicity test of single dose antagonism cotton bollworm
As shown in Table 1, metaflumizone and ethyl pleocidin composite, co-toxicity coefficient is all greater than 120, shows good synergistic function.
Adopt feed to add malicious method and carry out indoor synergy biologicall test, selection rice-stem borer is target pest, often processes repetition 3 times, calculates toxicity regression equation and the lethal concentration of 50 LC of each medicament antagonism striped rice borer by probability value method
50, use LC
50value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient, the results are shown in Table 2:
Table 2 metaflumizone and ethyl pleocidin is composite and single dose to the toxicity test of striped rice borer
As shown in Table 2, metaflumizone and ethyl pleocidin composite, all 120 are greater than to the co-toxicity coefficient of rice-stem borer, show good synergistic function.
Embodiment 2:
Take 5g metaflumizone, 50g ethyl pleocidin, triphen ethyl phenol polyoxyethylene ether phosphate 3g, agriculture breast 33#2g, 600#1g, solvent naphtha 13g, adds water to 100g.The method above raw material being prepared routinely aqueous emulsion drops into the mixing of mixing kettle high speed, forms the metaflumizone ethyl pleocidin aqueous emulsion that principle active component weight percentage is 55%.
Embodiment 3:
Take 2g metaflumizone, 18g ethyl pleocidin, calcium dodecyl benzene sulfonate 6g, triphen ethyl phenol polyoxyethylene ether phosphate 3g, agriculture breast 33#2g, 600#1g, cyclohexanone 10g, adds water to 100g.The method above raw material being prepared routinely microemulsion drops in mixing kettle and mixes, and forms the metaflumizone ethyl pleocidin microemulsion that principle active component weight percentage is 20%.
Carry out the control cotton bollworm test of pesticide effectiveness to embodiment 3, contrast medicament is 60 grams per liter ethyl pleocidin SC and 25% metaflumizone SC, and dilute according to the extension rate of form 3 li, look into 3 days after medicine, 7 days, the result of 14 days, result is in table 3:
Table 3: the field test results of the composite antagonism cotton bollworm of metaflumizone-ethyl pleocidin
Field efficacy result shows, metaflumizone ethyl pleocidin composition antagonism cotton bollworm has excellent control efficiency, and control efficiency is all better than the direct acting effect of single dose kind.
Carry out water prevention chilo suppressalis field medicine effect test to embodiment 3, contrast medicament is 60 grams per liter ethyl pleocidin SC and 25% metaflumizone SC, and dilute according to the extension rate of form 3 li, look into 3 days after medicine, 7 days, the result of 14 days, result is in table 4:
Table 4: the composite field test results to rice-stem borer of metaflumizone-ethyl pleocidin
Field efficacy result shows, metaflumizone ethyl pleocidin composition has excellent control efficiency to rice-stem borer, and control efficiency is all better than the direct acting effect of single dose kind.
Embodiment 4:
Take 1g metaflumizone, 5g ethyl pleocidin, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, solvent naphtha to 100g.The method above raw material being prepared routinely missible oil drops in mixing kettle and mixes, and forms the metaflumizone ethyl pleocidin missible oil that principle active component weight percentage is 6%.
Embodiment 5:
Take 50g metaflumizone, 20g ethyl pleocidin, calcium dodecyl benzene sulfonate 5g, phenethyl phenol polyethenoxy ether 2g, solvent naphtha are to 100g.The method above raw material being prepared routinely missible oil drops in mixing kettle and mixes, and forms the metaflumizone ethyl pleocidin missible oil that principle active component weight percentage is 70%.
Embodiment 6:
Take 2g metaflumizone, 40g ethyl pleocidin, calcium dodecyl benzene sulfonate 8g, phenethyl phenol polyethenoxy ether 5g, solvent naphtha are to 100g.The method above raw material being prepared routinely missible oil drops in mixing kettle and mixes, and forms the metaflumizone ethyl pleocidin missible oil that principle active component weight percentage is 42%.
Embodiment 7:
Take 0.2g metaflumizone, 50g ethyl pleocidin, calcium dodecyl benzene sulfonate 9g, phenethyl phenol polyethenoxy ether 8g, solvent naphtha are to 100g.The method above raw material being prepared routinely missible oil drops in mixing kettle and mixes, and forms the metaflumizone ethyl pleocidin missible oil that principle active component weight percentage is 50.2%.
Embodiment 8:
Take 5g metaflumizone, 0.5g ethyl pleocidin, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether 7g, solvent naphtha are to 100g.The method above raw material being prepared routinely missible oil drops in mixing kettle and mixes, and forms the metaflumizone ethyl pleocidin missible oil that principle active component weight percentage is 5.5%.
Embodiment 9:
Take 5g metaflumizone, 30g ethyl pleocidin, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 4g, solvent naphtha are to 100g.The method above raw material being prepared routinely missible oil drops in mixing kettle and mixes, and forms the metaflumizone ethyl pleocidin missible oil that principle active component weight percentage processed is 35%.
Embodiment 10:
Take 20g metaflumizone, 5g ethyl pleocidin, calcium dodecyl benzene sulfonate 7g, phenethyl phenol polyethenoxy ether 9g, solvent naphtha are to 100g.The method above raw material being prepared routinely missible oil drops in mixing kettle and mixes, and forms the metaflumizone ethyl pleocidin missible oil that preparation principle active component weight percentage is 25%.
Embodiment 11:
Take 30g metaflumizone, 12g ethyl pleocidin, sodium lignin sulfonate 2g, agriculture breast 33#4g, xanthans 0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, the weight percentage forming principle active component under the effect of sand mill is the metaflumizone ethyl pleocidin suspending agent of 42%.
Embodiment 12:
Take 2g metaflumizone, 5g ethyl pleocidin, sodium lignin sulfonate 8g, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, above raw material is the metaflumizone ethyl pleocidin water dispersion granule of 7% by the weight percentage of water dispersible granular agent method formation principle active component by diatomite 21g.
Embodiment 13:
Take 50g metaflumizone, 3g ethyl pleocidin, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, solvent naphtha are to 100g.The method above raw material being prepared routinely missible oil drops in mixing kettle and mixes, and the weight percentage forming principle active component is the metaflumizone ethyl pleocidin missible oil of 53%.
Embodiment 14:
Take 2g metaflumizone, 18g ethyl pleocidin, lignin 10g, Negel 2g, add to 100g with diatomite, mixed in micronizer by above raw material, the weight percentage forming principle active component is the metaflumizone ethyl pleocidin wetting powder of 20%.
Embodiment 15:
Take 7g metaflumizone, 70g ethyl pleocidin, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, solvent naphtha are to 100g.The method above raw material being prepared routinely missible oil drops in mixing kettle and mixes, and the weight percentage forming principle active component is the metaflumizone ethyl pleocidin missible oil of 77%.
Embodiment 16:
Take 60g metaflumizone, 5g ethyl pleocidin, sodium lignin sulfonate 8g, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, above raw material is the metaflumizone ethyl pleocidin water dispersible granules of 65% by the weight percentage of water dispersible granular agent method formation principle active component by kaolin 13g.
Claims (10)
1., containing a Pesticidal combination for metaflumizone and ethyl pleocidin, it is characterized in that this Pesticidal combination with metaflumizone and ethyl pleocidin for active insecticidal components, wherein, the weight ratio of metaflumizone and ethyl pleocidin is 0.1 ~ 80:0.5 ~ 80.
2. the Pesticidal combination containing metaflumizone and ethyl pleocidin according to claim 1, is characterized in that the weight ratio of described metaflumizone and ethyl pleocidin is 0.5 ~ 50:1 ~ 50.
3. the Pesticidal combination containing metaflumizone and ethyl pleocidin according to claim 2, is characterized in that the weight ratio of described metaflumizone and ethyl pleocidin is 1 ~ 17:1 ~ 20.
4. the Pesticidal combination containing metaflumizone and ethyl pleocidin according to claim 3, is characterized in that the weight ratio of described metaflumizone and ethyl pleocidin is 1 ~ 10:1.
5. the Pesticidal combination containing metaflumizone and ethyl pleocidin according to claim 1, is characterized in that both described metaflumizone and the ethyl pleocidin weight percentage in this Pesticidal combination is 3% ~ 80%.
6. the Pesticidal combination containing metaflumizone and ethyl pleocidin according to claim 5, is characterized in that both described metaflumizone and the ethyl pleocidin weight percentage in this Pesticidal combination is 5% ~ 55%.
7. the Pesticidal combination containing metaflumizone and ethyl pleocidin according to claim 1, is characterized in that this Pesticidal combination with metaflumizone and ethyl pleocidin for active insecticidal components and insecticides adjuvant and excipients are mixed with the formulation that agricultural chemicals allows.
8. the Pesticidal combination containing metaflumizone and ethyl pleocidin according to claim 7, is characterized in that described formulation is missible oil, suspending agent, aqueous emulsion, wetting powder, microemulsion or water dispersion granule.
9. the Pesticidal combination containing metaflumizone and ethyl pleocidin according to claim 1 is preparing the application prevented and treated on the insecticidal materials of resistance lepidoptera pest.
10. the Pesticidal combination containing metaflumizone and ethyl pleocidin according to claim 9 is preparing the application on the insecticidal materials preventing and treating cotton bollworm or snout moth's larva.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246190A (en) * | 2022-01-19 | 2022-03-29 | 安徽农业大学 | Insecticidal composition containing metaflumizone and Empedobacter brevis and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011126837A (en) * | 2009-12-21 | 2011-06-30 | Nippon Nohyaku Co Ltd | Agricultural and horticultural pest-controlling agent composition, and method for applying them |
| CN102349502A (en) * | 2011-09-13 | 2012-02-15 | 广西田园生化股份有限公司 | Ultralow-volume solvent containing pleocidin or spinetoram |
| CN102379297A (en) * | 2011-09-13 | 2012-03-21 | 广西田园生化股份有限公司 | Macrolide compound ultralow volume formulation |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011126837A (en) * | 2009-12-21 | 2011-06-30 | Nippon Nohyaku Co Ltd | Agricultural and horticultural pest-controlling agent composition, and method for applying them |
| CN102349502A (en) * | 2011-09-13 | 2012-02-15 | 广西田园生化股份有限公司 | Ultralow-volume solvent containing pleocidin or spinetoram |
| CN102379297A (en) * | 2011-09-13 | 2012-03-21 | 广西田园生化股份有限公司 | Macrolide compound ultralow volume formulation |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246190A (en) * | 2022-01-19 | 2022-03-29 | 安徽农业大学 | Insecticidal composition containing metaflumizone and Empedobacter brevis and application thereof |
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Effective date of registration: 20180516 Address after: 211318 Dongfeng Road 8, Yalong Town, Gaochun, Nanjing, Jiangsu Co-patentee after: Nanjing Redsun Co., Ltd. Patentee after: Nanjing Huazhou Pharmaceutical Co., Ltd. Address before: 211318 Dongfeng Road 8, Yalong Town, Gaochun, Nanjing, Jiangsu Patentee before: Nanjing Huazhou Pharmaceutical Co., Ltd. |