CN104621361A - Feed additive containing yeast cell polysaccharides - Google Patents
Feed additive containing yeast cell polysaccharides Download PDFInfo
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- CN104621361A CN104621361A CN201510111832.5A CN201510111832A CN104621361A CN 104621361 A CN104621361 A CN 104621361A CN 201510111832 A CN201510111832 A CN 201510111832A CN 104621361 A CN104621361 A CN 104621361A
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- yeast cells
- feed addictive
- piglet
- polysaccharide
- containing yeast
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Abstract
The invention provides a feed additive containing yeast cell polysaccharides. The feed additive is prepared from 90-95 percent of yeast cell polysaccharides, 2-6 percent of saccharomycetes, 1-3 percent of bacillus subtilis and 1-3 percent of bacillus licheniformis. The saccharomycetes, bacillus subtilis, bacillus licheniformis and yeast cell polysaccharides are compounded and matched with one another, so that the intestinal health level of piglets is improved, the body immunity is enhanced, and the antibody valence of piglet inject vaccines is improved.
Description
[technical field]
The present invention relates to a kind of feed addictive, be specifically related to a kind of feed addictive containing yeast cells polysaccharide, belong to field of feed processing.
[background technology]
Global investigation display, the life birth piglet of nearly 15-20% is at Preweaning death.Do not have innate immunity during piglet birth, self can not produce antibody, after need having colostrum, by colostrum, the antibody of parent is passed to piglet, is transitioned into self-produced antibody and adaptive immune power later.It is high-incidence season of infectious disease that piglet was come into being in 1 month, as swine fever, blue otopathy, pseudoabies etc., it is the susceptible disease of piglet within 1 monthly age, current raiser carrys out the generation of Control and prevention infectious disease mainly through vaccinate, but when giving sucking pig vaccinate, " vaccine immune response " reaction produced due to himself body is very low, therefore, vaccine tire undesirable.In addition, because the digestive organs of piglet are undeveloped, glandula digestive function is imperfect, as feeding is improper, is easy to suffer from diarrhoea.For the above-mentioned physilogical characteristics of sucking pig, most raiser rely in feed add antibiotic, antimicrobial carrys out preventing piglet diseases.And in recent years, antibiotic harm more and more by everybody cognition, even someone proposes, and forbids adding antibiotic in feed, exploitation is a kind of safe, healthy, and can effectively have great importance with the feed addictive improving piglet digestive function by develop immunitypty.
Yeast cells polysaccharide take yeast as raw material, utilize advanced biotechnology and process equipment, the explained hereafter such as to be separated, dry through self-dissolving, special enzymolysis, high speed centrifugation, product is containing the β-1 of 20-30%, 3/1,6 glucans and 20-30% manna oligosacchride are the efficient immunopotentiators of a kind of pure natural.Beta glucan is immunoreactive matrix, manna oligosacchride is a kind of important oligosaccharides, research shows, some microorganism harmful to animal body, as Escherichia coli, salmonella etc., using glucose as the main energy, beneficial bacterium such as Bifidobacterium, Bacillus acidi lactici etc. are then be main energy sources with oligosaccharides.
[summary of the invention]
The object of this invention is to provide a kind of feed addictive containing yeast cells polysaccharide, saccharomycete, bacillus subtilis and bacillus licheniformis and yeast cells polysaccharide composite is utilized to arrange in pairs or groups, to improve the intestinal health level of piglet, strengthen immunity of organisms, and improve the antibody titer of piggy injection vaccine.
For achieving the above object, technical scheme of the present invention is as follows:
A feed addictive containing yeast cells polysaccharide, according to weight percent meter, comprises yeast cells polysaccharide 90-95%, saccharomycete 2-6%, bacillus subtilis 1-3% and bacillus licheniformis 1-3%.
Preferably, a kind of feed addictive containing yeast cells polysaccharide, according to weight percent meter, composed of the following components: yeast cells polysaccharide 93%, saccharomycete 4%, bacillus subtilis 2% and bacillus licheniformis 1%.
Preferably, β-1,3/1,6 glucan of 20-30% and the manna oligosacchride of 20-30% is contained in described yeast cells polysaccharide.
Preferably, described saccharomycetic viable count be 200-900 hundred million/gram, the viable count of described bacillus subtilis be 1000-7000 hundred million/gram, the viable count of described bacillus licheniformis be 1000-7000 hundred million/gram.
Another object of the present invention is to provide a kind of feed for sow containing above-mentioned feed addictive.Preferably, in feed for sow, the adding proportion of above-mentioned feed addictive is 1.5-2.5kg/T.
Beneficial effect of the present invention is:
(1) the yeast cells polysaccharide in the present invention's formula contain can develop immunitypty glucan and contribute to the manna oligosacchride of intestinal beneficial bacteria growing, add in the sow feed of gestation itself or lactation, effectively can improve the immunity of piglet, improve the survival rate before weaned piglet, the toxic action of mycotoxin is eliminated and weakened to manna oligosacchride also by physical absorption or directly in conjunction with mycotoxin, reduces grice diarrhoea rate, improve efficiency of feed utilization, thus improve weaned piglet weight;
(2) bacillus subtilis in the present invention's formula has stronger bioenzyme activity, metabolism produces multiple enzyme as AMS, protease, lipase, cellulase etc., together play a role with the digestive enzymes in animal body in alimentary canal, improve food conversion ratio, and the free oxygen consumed rapidly in environment, build anaerobic environment, be conducive to the growth of the beneficial bacteriums such as lactic acid bacteria (comprising Bifidobacterium);
(3) antibiotic that the bacillus licheniformis in the present invention's formula produces in growth course, polymyxins, nystatin, gramicidins isoreactivity material, have obvious inhibitory action to the conditioned pathogen of pathogenic bacteria or autogenous infection;
(4) biologically active that the saccharomycete tool in the present invention's formula is extremely strong, secretes multiple digestive ferment, improves feed digestibility, reduce feed coefficient, and secrete unknown somatomedin, promote growth of animal, reduce feedstuff-meat ratio;
(5) feed addictive containing yeast cell wall polysaccharide of the present invention can be used as adjuvant, improves tiring of the vaccine of piglet, strengthens the specific immune response of piglet;
(6) feed addictive containing yeast cell wall polysaccharide of the present invention is added in the daily ration of milking sow, piglet liver function and non-specific immune systems can be improved.
[accompanying drawing explanation]
Fig. 1: utilize Elisa kit to detect the OD value of blue otopathy in piglet serum, pseudo-mad dog and hog cholera vaccine antibody;
Fig. 2: piglet serum alt (glutamic-pyruvic transaminase) and AST (glutamic-oxalacetic transaminease) content.
[detailed description of the invention]
Explain the present invention further below in conjunction with embodiment, but embodiment does not limit in any form to the present invention.When not specified (NS), involved in the present invention to method be conventional method, involved raw material is marketable material.
Embodiment 1
A feed addictive containing yeast cells polysaccharide, is made up of the component of following mass percent: yeast cells polysaccharide 90%, saccharomycete 6%, bacillus subtilis 3% and bacillus licheniformis 1%.Wherein, the β-1,3/1 of 30% is contained in described yeast cells polysaccharide, 6 glucans and 26% manna oligosacchride, described saccharomycetic viable count is 20,000,000,000/gram, the viable count of described bacillus subtilis is 1,000 hundred million/gram, the viable count of described bacillus licheniformis is 7,000 hundred million/gram.
Embodiment 2
A feed addictive containing yeast cells polysaccharide, is made up of the component of following mass percent: yeast cells polysaccharide 95%, saccharomycete 2%, bacillus subtilis 1% and bacillus licheniformis 2%.Wherein, the β-1,3/1 of 20% is contained in described yeast cells polysaccharide, 6 glucans and 30% manna oligosacchride, described saccharomycetic viable count is 90,000,000,000/gram, the viable count of described bacillus subtilis is 7,000 hundred million/gram, the viable count of described bacillus licheniformis is 4,000 hundred million/gram.
Embodiment 3
A feed addictive containing yeast cells polysaccharide, is made up of the component of following mass percent: yeast cells polysaccharide 93%, saccharomycete 4%, bacillus subtilis 2% and bacillus licheniformis 1%.Wherein, the β-1,3/1 of 25% is contained in described yeast cells polysaccharide, 6 glucans and 27% manna oligosacchride, described saccharomycetic viable count is 50,000,000,000/gram, the viable count of described bacillus subtilis is 5,000 hundred million/gram, the viable count of described bacillus licheniformis is 7,000 hundred million/gram.
Embodiment 4
A feed addictive containing yeast cells polysaccharide, is made up of the component of following mass percent: yeast cells polysaccharide 91%, saccharomycete 4%, bacillus subtilis 2% and bacillus licheniformis 3%.Wherein, the β-1,3/1 of 27% is contained in described yeast cells polysaccharide, 6 glucans and 20% manna oligosacchride, described saccharomycetic viable count is 50,000,000,000/gram, the viable count of described bacillus subtilis is 4,000 hundred million/gram, the viable count of described bacillus licheniformis is 1,000 hundred million/gram.
Below the compliance test result experiment of the feed addictive containing yeast cells polysaccharide of the present invention:
Experiment 1
Choose the sow 50 that genetic background is identical, parity is consistent, the gestational period is close, be divided at random 5 groups (each 5 repetitions, each repetition 2 sows): control group, experimental group 1, experimental group 2, experimental group 3 and experimental group 4.Wherein, any feed addictive obtained in embodiment 1-4 is not added in the daily ration (basal diet) of control group, add respectively in the daily ration of experimental group 1-4 according to obtained feed addictive of filling a prescription described in embodiment 1-4, its adding proportion is respectively 1.5kg/T, 1.8kg/T, 2kg/T, 2.5kg/T.Duration of test swinery free choice feeding and drinking-water, feeding and management and immunity, care procedure carry out according to pig farm conventional program.Experimental period terminates from 80 days sow gestation phases to the child care phase of piglet, adds up and survival rate, weaning weight before calculating the young number of equal Duan Nai Waterloo of each group of sow, weaned piglet, piglet cradling Qi Waterloo young number, child care phase survival rate, piglet 7-52 age in days diarrhea rate.Result is as shown in table 1:
The growing state statistics of piglet in each group of table 1
As shown in Table 1, the a certain amount of feed addictive containing yeast cells polysaccharide of the present invention is added in sow diets, effectively can increase the young number of sow equal Duan Nai Waterloo, survival rate, weaning weight, child care phase survival rate before raising weaned piglet, reduce the diarrhea rate of 7-52 age in days piglet.
Experiment 2
Select newborn piglet 60, originate from that identical, the parity of gene is consistent respectively, body weight and the gestational period close sow.Each head sow is made to be with young number identical by rationally entrusting one's child to the care of sb., the gross weight of Chu Shi Waterloo heavy (full Waterloo piglet) close.Be divided into control group and experimental group (each 3 repetitions at random, each repetition 10 piglets), milking sow feeding basal diet in control group, add the feed addictive of formula described in embodiment 3 with the ratio of 2kg/T in the basal diet of the milking sow in experimental group, experiment periods is from piglet 7 age in days to 42 ages in days, totally 35 days, and in piglet 7 age in days, blue-ear disease vaccine is injected respectively when 14 ages in days and 21 age in days, pseudo-rabies vaccine and hog cholera vaccine, at the end of experiment, each repetition Stochastic choice piglet, Elisa kit is utilized to detect the corresponding antibody titer of above-mentioned vaccine in piglet serum, to reflect the impact of feed addictive of the present invention on specific immune response.As shown in Figure 1, the OD value recording three kinds of vaccine antibodies in experimental group piglet serum is all significantly higher than control group, illustrates that feed addictive of the present invention can improve the antibody titer of piggy injection vaccine, strengthens the specific immune response of piglet.
The content of serum alt (glutamic-pyruvic transaminase) and AST (glutamic-oxalacetic transaminease) is the whether normal important indicator of reaction liver function, and liver organization is impaired or the ALT (glutamic-pyruvic transaminase) in blood and AST (glutamic-oxalacetic transaminease) content all can be made when destroying to raise.Liver is the maximum removing toxic substances organ of body, and be also the important digestive organs of piglet, hypogenetic digestive system has larger negative effect to the growth of piglet after lactation and wean.Therefore, at the end of experiment, have detected the content of ALT (glutamic-pyruvic transaminase) and AST (glutamic-oxalacetic transaminease) in piglet serum, to reflect liver function and the innate immune activity of piglet.As shown in Figure 2, feed addictive of the present invention is added in the daily ration of milking sow, significantly can reduce the content of piglet serum alt (glutamic-pyruvic transaminase) and AST (glutamic-oxalacetic transaminease), thus improve liver function and the digestive system of piglet.
Claims (6)
1. the feed addictive containing yeast cells polysaccharide, it is characterized in that, according to weight percent meter, described feed addictive comprises yeast cells polysaccharide 90-95%, saccharomycete 2-6%, bacillus subtilis 1-3% and bacillus licheniformis 1-3%.
2. the feed addictive containing yeast cells polysaccharide according to claim 1, it is characterized in that, according to weight percent meter, described feed addictive is composed of the following components: yeast cells polysaccharide 93%, saccharomycete 4%, bacillus subtilis 2% and bacillus licheniformis 1%.
3. the feed addictive containing yeast cells polysaccharide according to claim 1 and 2, is characterized in that, containing β-1,3/1,6 glucan of 20-30% and the manna oligosacchride of 20-30% in described yeast cells polysaccharide.
4. the feed addictive containing yeast cells polysaccharide according to claim 1 and 2, it is characterized in that, described saccharomycetic viable count be 200-900 hundred million/gram, the viable count of described bacillus subtilis be 1000-7000 hundred million/gram, the viable count of described bacillus licheniformis be 1000-7000 hundred million/gram.
5. a sow feed, is characterized in that the feed addictive containing yeast cells polysaccharide be added with in described sow feed according to any one of claim 1-4.
6. sow feed according to claim 5, is characterized in that, the adding proportion of the described feed addictive containing yeast cells polysaccharide is 1.5-2.5kg/T.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510111832.5A CN104621361A (en) | 2015-03-13 | 2015-03-13 | Feed additive containing yeast cell polysaccharides |
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| CN201510111832.5A CN104621361A (en) | 2015-03-13 | 2015-03-13 | Feed additive containing yeast cell polysaccharides |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105661039A (en) * | 2016-01-20 | 2016-06-15 | 四川中农致远生物科技有限公司 | Breeding sow feed additives and preparation method thereof |
| CN106578386A (en) * | 2016-12-20 | 2017-04-26 | 河南科技学院 | Thymol new application |
| CN107259141A (en) * | 2017-06-13 | 2017-10-20 | 湖南绿亨世源动物药业有限公司 | The feed addictive and its making application method of a kind of in-pig |
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| CN101669576A (en) * | 2008-09-12 | 2010-03-17 | 安琪酵母股份有限公司 | Yeast composition and feed |
| CN103461742A (en) * | 2013-10-14 | 2013-12-25 | 双胞胎（集团）股份有限公司 | Sow feed and breeding mode thereof |
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2015
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Patent Citations (3)
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| WO2004034810A2 (en) * | 2002-10-09 | 2004-04-29 | Basf Aktiengesellschaft | Animal food additives containing a vitamin b6 and/or the salts thereof and method for producing said additives |
| CN101669576A (en) * | 2008-09-12 | 2010-03-17 | 安琪酵母股份有限公司 | Yeast composition and feed |
| CN103461742A (en) * | 2013-10-14 | 2013-12-25 | 双胞胎（集团）股份有限公司 | Sow feed and breeding mode thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105661039A (en) * | 2016-01-20 | 2016-06-15 | 四川中农致远生物科技有限公司 | Breeding sow feed additives and preparation method thereof |
| CN106578386A (en) * | 2016-12-20 | 2017-04-26 | 河南科技学院 | Thymol new application |
| CN107259141A (en) * | 2017-06-13 | 2017-10-20 | 湖南绿亨世源动物药业有限公司 | The feed addictive and its making application method of a kind of in-pig |
| CN107259141B (en) * | 2017-06-13 | 2021-06-22 | 湖南绿亨世源动物药业有限公司 | Feed additive for pregnant sows and preparation and use methods thereof |
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Application publication date: 20150520 |