CN104524343A - Traditional Chinese medicine preparation for preventing and treating tuberculosis and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for preventing and treating tuberculosis and preparation method thereof Download PDF

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CN104524343A
CN104524343A CN201510029142.5A CN201510029142A CN104524343A CN 104524343 A CN104524343 A CN 104524343A CN 201510029142 A CN201510029142 A CN 201510029142A CN 104524343 A CN104524343 A CN 104524343A
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radix
parts
rhizoma
chinese medicine
medicine preparation
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刘伟
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Abstract

The invention discloses a traditional Chinese medicine preparation for preventing and treating tuberculosis. The traditional Chinese medicine preparation consists of the following components according to a certain weight ratio: radix pseudostellariae, roasted rhizoma atractylodis macrocephalae, stir-baked rhizoma dioscoreae, poria cocos, astragalus, angelica sinensis, white paeony root, prepared rehmannia root, spina date seed, polygala tenuifolia, the fruit of Chinese wolfberry, tortoise plastron, human placenta, cornu cervi degelatinatum, rhizoma phragmitis, the root of kudzu vine, platycodon grandiflorum, raw semen coicis, hairyvein agrimony, madder, divaricate saposhnikovia root and rhizoma anemarrhenae. The traditional Chinese medicine preparation has the effects of tonifying spleen and lung, eliminating dampness, inducing diuresis and nourishing yin and enriching the blood and can be used for effectively preventing and treating the tuberculosis.

Description

A kind of Chinese medicine preparation for tuberculosis prevention and treatment and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for tuberculosis prevention and treatment.The invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Tuberculosis is a kind of chronic infectious disease of serious harm people ' s health, and by mycobacteria, (mainly mycobacterium tuberculosis (Mycobacterium tuberculosis), causes also known as " tubercule bacillus " (tubercle bacillus).Tuberculosis usually infects and destroys lung and (claims " pulmonary tuberculosis ", also known as " pulmonary tuberculosis " or be called " spitting of blood sick ") and lymphsystem (claim " Tuberculous lymphadenopathy ", also known as " lymphoid tuberculosis "), but other organ as brain, central nervous system, blood circulation, urinary system, skeleton, joint, even skin also can infected (as infect brain can cause " tuberculous meningitis ").China's tuberculosis number of patients occupies second place of the world, is only second to India.Tuberculosis is one of major disease of China's priority control.Tuberculosis is the highest with juvenile onset rate, and according to statistics, the whole world about has 1,700,000,000 people to infect tuberculosis, every year dead 3,000,000 people, and therefore tuberculosis becomes " the second cancer " by a lot of people.
Tubercule bacillus passes through respiratory tract infection, attack pulmonary at first, when Abwehrkraft des Koepers reduction to be easy to cause the inflammatory infiltration sexually transmitted disease (STD) of lungs to become, clinical manifestation weight lungy differs, common are local and the General Symptomies such as cough, expectoration, hemoptysis, chest pain, heating, weak, loss of appetite, onset can suddenly can be delayed, and mostly is low grade fever, night sweat, weak, poor appetite, becomes thin, female menstrual disorder etc.; Respiratory symptom has cough, expectoration, spitting of blood, chest pain, in various degree uncomfortable in chest or dyspnea.Bone tuberculosis is mostly by pulmonary tuberculosis secondary.First tuberculosis sclerotium occurs in pulmonary mostly, can be gone, can cause skeletal system tuberculosis after pulmonary infection by the propagation of blood to a lot of system of whole body, so bone tuberculosis is not simple pathological changes, is the performance of general disease in local.Spinal column is the modal site of pathological change of bone tuberculosis.
Current modern medicine is used for the treatment of lungy mainly based on Western medicine, as rifampicin, streptomycin etc., these medicines not only have many side effect, and along with long-term and irrational adaptation, the drug resistance of tulase also can be more and more higher, many patients are had the tubercle bacillus affection of drug resistance, common drug is without any therapeutic effect, cause the present situation that therapeutic effect is unsatisfactory, many toxic and side effects of medicine also make patient beyond affordability, cause therapy discontinued, form old tuberculose focus.The traditional Chinese medical science is said, prevention of diseae, preventing exacerbation after being taken ill, be therefore also very important in control lungy.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation, this Chinese medicine preparation has control for treatment tuberculosis prevention and treatment and takes into account, and successful is cheap, easy to use, the feature had no side effect.
Another object of the present invention is to provide the preparation method of the Chinese medicine preparation of this treatment tuberculosis prevention and treatment.
Inventor is in clinical treatment practice for many years, observe the misery that tuberculosis is brought to patient, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula of the Chinese medicine preparation for tuberculosis prevention and treatment repeatedly, the present invention selects Radix Pseudostellariae, Rhizoma Atractylodis Macrocephalae (parched), Rhizoma dioscoreae (parched), Poria, the Radix Astragali, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Semen Ziziphi Spinosae, Radix Polygalae, Fructus Lycii, Carapax et Plastrum Testudinis, Placenta Hominis, Cornu Cervi Degelatinatum, Rhizoma Phragmitis, Radix Puerariae, Radix Platycodonis, Semen Coicis, Herba Agrimoniae, Radix Rubiae, Radix Saposhnikoviae, the Rhizoma Anemarrhenae combines, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is benefit strengthening spleen and lung, dampness diuretic, effect of nourishing YIN and supplementing blood, thus effectively can prevent and treat tuberculosis.
The effect of Chinese medicine of the present invention:
Wherein:
Radix Pseudostellariae: for Caryophyllaceae Radix Pseudostellariae belongs to the dry root of (Pseudostellaria) plant Radix Pseudostellariae.Nature and flavor: sweet, micro-hardship, tepor.Return lung, spleen channel.Effect: mend strengthening spleen and lung, supplementing QI for promoting the production of body fluid.Control cough due to deficiency of the lung, insufficiency of the spleen lack of appetite, cardiopalmus, palpitation with a distress feeling, edema, quenches one's thirst, metal fatigue.Join Radix Ophiopogonis, tonifying the lung nourishing lung-YIN, the most suitable with the cough due to deficiency of the lung controlling lung yin virtual loss.Join the Rhizoma Atractylodis Macrocephalae, play the merit of spleen reinforcing lung altogether.To rule together asthenia, the weak person of overstrain.Tcm clinical practice uses widely.Generally have xerostomia, agitation, cardiopalmus, insomnia, patient that is weak, the deficiency of both QI and YIN symptom such as lack of appetite, feverish sensation in the palms and soles all can use.The Radix Pseudostellariae property of medicine is very steady, and applicable chronic patient is taken for a long time in a large number, empty and be unable to bear that to nourish medicine high benefit people be best selection for those bodies, and can not cause elevation of the blood pressure, the symptom such as to get angry.
Rhizoma Atractylodis Macrocephalae (parched): be the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..Nature and flavor: bitter, sweet, temperature.Return spleen, stomach warp.Effect: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive, the Rhizoma Atractylodis Macrocephalae can air making-up and spleen enlivening, again can dampness diuretic, is the key medicine of the spleen strengthening and damp drying.In the sweet temperature compensation of the Rhizoma Atractylodis Macrocephalae, can air making-up and spleen enlivening, also can strengthening superficial resistance to stop perspiration, and the Radix Astragali, Radix Pseudostellariae compatibility, play the merit of spleen reinforcing lung altogether.To rule together asthenia, the weak person of overstrain.Rhizoma Atractylodis Macrocephalae antibacterial action is obvious: infusion has inhibitory action to acrothesium floccosum, star nocardia in vitro.
Rhizoma dioscoreae (parched): be the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae Dioscorea opposita Thunb..Nature and flavor: flat, sweet.Return spleen, lung, kidney channel.Effect: spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Poria: be the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.Nature and flavor: sweet, light, flat.GUIXIN, lung, spleen, kidney channel.Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Sweet the providing additional supplies of this product is oozed, and not only mends but also sharp, and effect is gentle, and property is flat and partially without cold and heat, is the key medicine of promoting diuresis to eliminate damp pathogen.Treatment water wet the edema of expert time, often join Rhizoma Alismatis, Polyporus.Poria decoct has obvious sedation." modality ": " cure mainly Ji Rou Shun muscle of throbbing with fear cautious, dizziness agitation is controlled on side." this product is by heart-spleen boosting and tranquilizing mind.Be used for deficiency of both the heart and spleen, the irritability of insufficiency of vital energy and blood.
The Radix Astragali: be the dry root of leguminous plant Radix Astagali Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao or Radix Astragali Astragalus membranaceus (Fisch.) Bge..Nature and flavor: sweet, tepor.Return lung, spleen, liver, kidney channel.Effect: tonifying Qi and lifting yang, consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, the evacuation of pus of holder skin ulcer, regulating fluid apssage.On the books in " book on Chinese herbal medicine converges and says ": " Radix Astragali, tonifying the lung spleen invigorating defend arresting sweating in fact, and the medicine of wind dispelling fortune poison also.Therefore the people of yang deficiency, spontaneous perspiration frequently comes, be exterior deficiency and interspaces of skin and muscles being loose also, he the Radix Astragali can be defended and arresting sweating in fact; The card of typhoid fever, row is delivered and evil no sweating, and be interior deficiency and also weary in healthy energy, the Radix Astragali can help Tianjin to help antiperspirant; The disease of harmful wind, inclined invasion of vessels and brothers are not with person, and the Radix Astragali can flourish muscles and bones; The card of carbuncle and ulcer, pus and blood internal ulceration, deficiency of YANG QI and do not hold back person, the Radix Astragali can granulation promoting meat, and the erosion of vulva can not rise and send out again, deficiency of YANG QI and unhealed, and the Radix Astragali can granulation promoting meat." this product all has inhibitory action to dysentery bacterium, anthrax bacillus, α-hemolytic streptococcus, beta hemolytic streptococcus, diphtheria corynebacterium, bacillus pseudodiphthericus, Diplococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus, bacillus subtilis etc. in vitro.
Radix Angelicae Sinensis: be the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Nature and flavor: sweet, pungent, bitter, temperature.Return liver, the heart, spleen channel.Effect: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Radix Angelicae Sinensis has inhibitory action to central nervous system, and volatile oil has the effects such as calmness, hypnosis, analgesia, anesthesia.For blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores.Carry according to " book on Chinese herbal medicine is just ": its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable.
The Radix Paeoniae Alba: be the dry root of dicotyledon ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Nature and flavor: cool, picric acid, is slightly cold.Effect: easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving, yin fluid astringing receives antiperspirant.Research shows: the paeoniflorin contained in the Radix Paeoniae Alba has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.This product energy nourishing the liver blood, holding back liver-yin, subduing the hyperfunction of the liver sun, dispersing liver-energy, can delay again that contraction is anxious, relieve the pain pain, is the good medicine of the various pain for the treatment of Liver Channel.
Radix Rehmanniae Preparata: be scrophulariaceae rehmannia glutinosa plant (Rehmannia glutinosa(Gdertn) Iibosch.ex Fisch. et Mey.) tuber form through Processing methods.Nature and flavor: sweet, tepor.Return liver, kidney channel.Effect: nourishing YIN and supplementing blood, beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.Radix Rehmanniae Preparata can be enriched blood YIN nourishing and liver-nourishing kidney-boosting, and all blood deficiency the moon loses, dizzy caused by deficiency of the liver and kindey, all can apply.
Semen Ziziphi Spinosae: be the dry mature seed of Rhamnaceae plant Ziziphi Spinosae Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H.F.Chou.Nature and flavor: flat, sweet, sour.GUIXIN, spleen, liver, gallbladder meridian.Effect: nourishing the liver, mind calming, calms the nerves, arresting sweating." Bencao Jingshu ": Semen Ziziphi Spinosae, real acid is flat, and core is then held concurrently sweet.Special tonifying liver gallbladder, is also amusing again.Ripe then fragrance, fragrance enters spleen, therefore can return spleen.Can courage be mended, therefore can warm gallbladder.The gas phase of mothers and sons is led to, therefore also main fidgets due to deficiency, vexatious insomnia.Its main trusted subordinate's cold and heat, pathogens agglomerating gas gathers, and painful limbs arthralgia chiefly caused by damp pathogen person, all insufficiency of the spleen disease by heresy, spleen governing limbs therefore also.Gallbladder be all dirty first of, 11 dirtyly all depend on gallbladder, and the vital essence of the five internal organs, all reports in spleen, therefore takes it for a long time, function settling five organs.
Radix Polygalae: be the dry root of Polygalaceae herbaceos perennial Radix Polygalae Polygala tenuifolia Willd. and ovum leaf Radix Polygalae P.sibirica L..Nature and flavor: warm, bitter, pungent.GUIXIN, kidney, lung meridian.Effect: mind tranquilizing and the heart calming, go expectorant to have one's ideas straightened out, eliminating carbuncle eliminating stagnation.Radix Polygalae acrid in the mouth tonneau, can eliminate the phlegm, again sharp thinking, and for controlling phlegmatic mental confusion, epilepsy is gone mad, and normal and Rhizoma Acori Graminei, Radix Curcumae are used together.And Radix Polygalae is good at restoring normal coordination between the heart and kidney, make regulation between water and fire, the beneficial motive of energy, tranquilizing mind, spasmolytic is throbbed with fear, and opens wisdom.
Fructus Lycii: be the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..Nature and flavor: sweet, flat.Return liver, kidney channel.Effect: nourishing the liver and kidney, replenishing vital essence to improve eyesight.Cure mainly: caused by liver and kidney deficiency; Have a dizzy spell; Visual unclear; Soreness of the waist and knees; Impotence and seminal emission; Cough due to consumptive disease; To quench one's thirst taking fluids profusely.Fructus Lycii contains the required nutrition of the healthy eye such as calcium, ferrum such as abundant carotene, retinol1, B1, B2, C, therefore is good at improving eyesight, so be commonly called as " bright eye ".The blurring of vision that ancient Chinese medicine doctor treatment deficiency of liver-blood, deficiency of kidney-YIN cause and nyctalopia, usually use Fructus Lycii.Fructus lycii extracted solution has delaying senility function and function for tonifying kidney.
Carapax et Plastrum Testudinis: be sternite and the carapace of Testudinidae animal chinemys reevesii.Nature and flavor: salty, sweet, be slightly cold.Return liver, kidney, heart channel.Effect: nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, Gu through only collapsing, reinforcing the heart of nourishing blood.Carapax et Plastrum Testudinis contains several amino acids, protein, fat and calcium salt etc. containing bone gelatin, hydrolysate.Cure mainly hyperactivity of YANG due to deficiency of YIN, yin asthenia generating intrinsic heat, stirring-up of pathogenic wind in the interior resulting from deficiency.To suffer from a deficiency of the kidney the atrophic debility of bones, infantile metopism.Deficiency of YIN-blood, palpitation with fear, insomnia, forgetful.This product energy tonifying kidney-yin is appointed with Gu Chong, again heat clearing away cold in nature, and holding concurrently can cooling blood for hemostasis.This product can nourish blood reinforcing the heart, can be used for insomnia forgetfulness.
Placenta Hominis: be the dry Placenta Hominis of Healthy People.Fresh human placenta being removed amniotic membrane and umbilical cord, repeatedly rinsing to removing blood, after steaming or putting and slightly boil in boiling water, dry.Nature and flavor: sweet, salty, temperature.GUIXIN, lung, kidney channel.Effect: the kidney warming mends essence, benefiting QI and nourishing blood.For asthenia weakness and emaciation, hectic fever due to YIN-deficiency night sweat, cough and asthma, lack of appetite is breathed hard, impotence and seminal emission, infertile hypogalactia.Can be used for disease such as treatment bronchial asthma, chronic bronchitis etc. clinically." herbal classic is met former ": Placenta Hominis possess essence and blood knot pregnant after liquid, obtain female QI and blood in the majority, therefore can high benefit nutrient blood, in order to control hectic fever due to YIN-deficiency weakness and emaciation, breathe heavily the disease of asthenia of coughing, be tonifying with drugs of thick flavor also.
Cornu Cervi Degelatinatum: for Cornu Cervi removes photoresist the hornblock (boil Colla cornus cervi remaining bone slag) of matter.Nature and flavor: salty, warm.Return liver, kidney channel.Effect: warming the kidney to activate YANG, astringing to arrest bleeding.For spleen kidney yang flaccidity, lack of appetite and vomiting, leucorrhea, enuresis frequent micturition, metrostaxis, carbuncle sucutaneous nodule.
Rhizoma Phragmitis: be the fresh or dry rhizome of grass phragmites communis Phragmites communis Trin..Nature and flavor: sweet, cold.Return lung meridian, stomach warp.Function: clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.Cure mainly: for calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.Rhizoma Phragmitis one medicine, is mainly used in following two aspects clinically, can clearing away lung-heat and evacuation of pus of eliminating the phlegm, again can clearing away stomach-heat and the preventing or arresting vomiting that promotes the production of body fluid.Though its attribute is trembled with fear, slightly sweet flavor and power use lung heat clearing stomach, can only as auxiliary medicine.But, it has an advantage, and namely property is not grown greasy, promotes the production of body fluid and does not love heresy, and all epidemic febrile disease deep loves are defended, gas, or if any the syndrome that impairment of body fluid is thirsty after calentura, all can apply.
Radix Puerariae: be the dry root of legume pueraria lobata Pueraria lobata (Willd.) Ohwi.Nature and flavor: cool, sweet, pungent.Enter spleen, stomach warp.Effect: induce sweat and bring down a fever, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Radix Puerariae is sweet pungent cool in nature, and lightly floating, it is loose to rise, and enters taste warp, has relieving the exterior syndrome by diaphoresis, the merit of expelling pathogenic factors from muscles for reducing heat.Radix Puerariae has diaphoresis, antipyretic effect, can be used for exterior heat disease with compatibilities such as Radix Bupleuri; With Herba Ephedrae, Ramulus Cinnamomi, Radix Paeoniae with seeing stiff nape and back, lossless, aversion to wind person with controlling wind and cold table disease.Radix Puerariae has treating measles effect, promotes the production of body fluid, diarrhea-relieving function because it has concurrently, so measles heating is thirsty, or with diseases such as diarrhoea, often and the fit applications such as Rhizoma Cimicifugae.This product again can promoting the production of body fluid to quench thirst, thirsty to calentura, or the disease such as to quench one's thirst, and can join Radix Ophiopogonis, Radix Trichosanthis is equivalent uses.This product performance sending up the lucid YANG, inspire taste yang-energy to rise, have the effect prevented and have loose bowels, clinical normal cooperation Radix Codonopsis, Bai Intraoperative etc. treat diarrhea due to hypofunction of the spleen; But can Rhizoma Coptidis, Radix Scutellariae etc. be joined, for diseases such as damp-heat dysenteries.
Radix Platycodonis: be the root of dicotyledon campanulaceae Campanulaceae Radix Platycodonis Platycodon grandiflorum (Jacq.) A. DC..Nature and flavor are bitter, pungent, tepor.Enter lung meridian.Effect: lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, foster the spirit of nobility.Radix Platycodonis is lung meridian edema caused by disorder of QI medicine, and pains are put down, and namely rises and falls, being good at a surname and opening lung qi, therefore exopathogen violates lung, cough with copious phlegm, and disease such as grade uncomfortable in chest of having a stuffy nose, no matter cold and heat all can adapted.
Semen Coicis: be the dry mature kernal of grass Semen Coicis Coix lacryma-jobi L. var. ma-yuen (Roman.) Stapf.Nature and flavor: sweet, light, cool.Return spleen, stomach, lung meridian.Effect: spleen invigorating eliminating dampness by diuresis, eliminating impediment pain relieving, clearing away heat and discharging pus.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.This product has again a merit of spleen invigorating, and in order to control edema due to deficiency of the spleen, beriberi swells and ache, and compatibility Poria, Bai Intraoperative, Fructus Chaenomelis, Fructus Evodiae is equivalent uses.
Herba Agrimoniae: be the aerial parts of Rosaceae herbaceos perennial Agrimony Agrimonia pilosa Ledeb..Nature and flavor: bitter, puckery, flat.GUIXIN, Liver Channel.Effect: astringing to arrest bleeding, removing toxic substances, dysentery relieving, parasite killing cuts cruel.For hemoptysis, spit blood, control epistaxis and have specially good effect, malaria, de-power impairment caused by overstrain, carbuncle.This product puckery convergence and property is put down, no matter the going out blood disorder and all can apply of cold and heat and asthenia and sthenia.Treatment heat in blood is hemorrhage normal to be used together with Radix Rehmanniae, Cortex Moutan.
Radix Rubiae: be the dry root and rhizome of Maguireothamnus speciosus Radix Rubiae Rubia cordifolia L..Nature and flavor: bitter, cold.Return Liver Channel.Effect: removing heat from blood, hemostasis, blood stasis dispelling, stimulates the menstrual flow.For spitting blood, epistaxis, metrorrhagia, traumatic hemorrhage, amenorrhea stasis blocking, arthralgia, tumbling and swelling.Clinical practice: for the multiple hemorrhage card of bleeding due to blood-heat.Radix Rubiae cold in nature enter blood system, can cooling blood for hemostasis, and can blood stasis dispelling.The going out blood disorder and all can select of all bleeding due to blood-heaies, the stasis of blood person that holds concurrently is especially suitable.Control the cards such as heat in blood spitting of blood, haematemesis, epistaxis, hematuria.
Radix Saposhnikoviae: be the dry root of umbelliferae Saposhnikovia divaricata Saposhnikovia divaricata (Turcz.) Schischk..Nature and flavor: pungent, sweet, tepor.Return bladder, lung, spleen, Liver Channel.Effect: expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.For diseases caused by exogenous pathogenic factor exterior syndrome or rubella pruritus.This product slightly warm in nature and not dry, sweet slow and not high, there is the title of " the profit agent in wind medicine ", no matter wind and cold, wind heat exterior syndrome all can be applied.This product also can be used for tetanus, gnathospasma, opisthotonus.Radix Saposhnikoviae controls tetanus, has the effect of expellingging wind and relieving convulsion.
The Rhizoma Anemarrhenae: be the dry rhizome of liliaceous plant Rhizoma Anemarrhenae Anemarrhena asphodeloides Bunge..Nature and flavor: bitter, sweet, cold.Return lung, stomach, kidney channel.Effect: clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.The disease of the lung sthenia gastropyrexias such as, full and large pulse fidgety, thirsty for epidemic febrile disease, high heat and dyspnea and cough due to lung-heat, expectorant are yellow and thick.Rhizoma Anemarrhenae bitter cold, upper energy clearing away lung-heat, middle energy clearing stomach fire, therefore be applicable to the disease that lung stomach has excess-heat.Rhizoma Anemarrhenae energy purte the white and nourishing kidney, therefore can not only excess-heat clearly, and can clearind deficient heat.Many and the same use of Cortex Phellodendri, allocates in drugs for nourishing yin, as ZHIBAI DIHUANG WAN, controls the disease such as hyperactivity of fire caused by deficiency of YIN, hectic fever hectic fever due to YIN-deficiency clinically.This product joins nourishing YIN and moistening the lung medicine as product such as Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Bulbus Fritillariae Cirrhosae again, can be used for deficiency of the lung cough caused by dryness; Join clearing away heat and promoting production of body fluid medicine as product such as Radix Trichosanthis, Radix Ophiopogonis, RADIX PUERARIAE, available controlling is quenched one's thirst.
Side's solution of the present invention is: in side, Radix Pseudostellariae mends strengthening spleen and lung, supplementing QI for promoting the production of body fluid, Rhizoma Atractylodis Macrocephalae (parched) invigorating the spleen and benefiting QI, dampness diuretic, Rhizoma dioscoreae (parched) spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, Poria promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming, Radix Astragali consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, the above five tastes are monarch drug altogether, fundamentally the body that takes care of health is moistened at health, conditioning health, strengthen patient's body constitution, disease is allowed no longer to recur, Chinese angelica blood supplementing is invigorated blood circulation, the pain relieving of Radix Paeoniae Alba suppressing the hyperactive liver, yin fluid astringing receives antiperspirant, Radix Rehmanniae Preparata nourishing YIN and supplementing blood, benefit essence fills out marrow, Semen Ziziphi Spinosae nourishing the liver mind calming, to calm the nerves arresting sweating, Radix Polygalae mind tranquilizing and the heart calming, expectorant is gone to have one's ideas straightened out, Fructus Lycii nourishing the liver and kidney, replenishing vital essence to improve eyesight, Carapax et Plastrum Testudinis nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, above seven tastes are ministerial drug altogether, assist a ruler in governing a country effect that monarch drug mends strengthening spleen and lung, also add enriches blood invigorates blood circulation, nourishing YIN and supplementing blood, effect of mind tranquilizing and the heart calming, make focus at bone, and the patient of pulmonary can alleviate the misery of focus by blood circulation promoting and blood stasis dispelling, accelerate the rehabilitation of patient.Placenta Hominis the kidney warming mends essence, benefiting QI and nourishing blood, Cornu Cervi Degelatinatum warming the kidney to activate YANG, astringing to arrest bleeding, Rhizoma Phragmitis, Radix Puerariae clearing away heat and promoting production of body fluid, Radix Platycodonis lung qi dispersing eliminates the phlegm, sore-throat relieving evacuation of pus, Semen Coicis spleen invigorating eliminating dampness by diuresis, eliminating impediment pain relieving, Herba Agrimoniae astringing to arrest bleeding, Radix Rubiae cooling blood for hemostasis, blood stasis dispelling are stimulated the menstrual flow, Radix Saposhnikoviae expelling pathogenic wind from the body surface, removing dampness to relieve pain, Rhizoma Anemarrhenae clearing away heat-fire, promote the production of body fluid and moisturize, above a few taste is adjuvant drug altogether, increases curative effect of medication, reduce the strong of medicine simultaneously, reduce the toxic and side effects of medicine.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, have the effect of mending strengthening spleen and lung, dampness diuretic, nourishing YIN and supplementing blood, effectively can treat tuberculosis prevention and treatment.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Radix Pseudostellariae 4-14 part, Rhizoma Atractylodis Macrocephalae (parched) 10-20 part, Rhizoma dioscoreae (parched) 10-20 part, Poria 10-20 part, Radix Astragali 19-29 part, Radix Angelicae Sinensis 13-23 part, Radix Paeoniae Alba 7-17 part, Radix Rehmanniae Preparata 10-20 part, Semen Ziziphi Spinosae 13-23 part, Radix Polygalae 7-17 part, Fructus Lycii 10-20 part, Carapax et Plastrum Testudinis 7-17 part, Placenta Hominis 5-15 part, Cornu Cervi Degelatinatum 7-17 part, Rhizoma Phragmitis 15-25 part, Radix Puerariae 7-17 part, Radix Platycodonis 10-20 part, Semen Coicis 19-29 part, Herba Agrimoniae 13-23 part, Radix Rubiae 7-17 part, Radix Saposhnikoviae 5-15 part, Rhizoma Anemarrhenae 4-14 part.
Wherein be preferably: Radix Pseudostellariae 9 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Rhizoma dioscoreae (parched) 15 parts, 15 parts, Poria, the Radix Astragali 24 parts, Radix Angelicae Sinensis 18 parts, the Radix Paeoniae Alba 12 parts, Radix Rehmanniae Preparata 15 parts, Semen Ziziphi Spinosae 18 parts, Radix Polygalae 12 parts, Fructus Lycii 15 parts, Carapax et Plastrum Testudinis 12 parts, Placenta Hominis 10 parts, Cornu Cervi Degelatinatum 12 parts, Rhizoma Phragmitis 20 parts, Radix Puerariae 12 parts, Radix Platycodonis 15 parts, Semen Coicis 24 parts, Herba Agrimoniae 18 parts, 12 parts, Radix Rubiae, Radix Saposhnikoviae 10 parts, the Rhizoma Anemarrhenae 9 parts.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, as pill, powder, tablet, oral liquid etc.Such as these crude drug pulverize mix homogeneously can be made powder to take after mixing it with water; Can decocting be used, obtain filtrate after filtration, add antiseptic and make oral liquid; Also directly decoction can be taken if desired.
The preferred preparation method of the present invention is decoction, and its preparation method is as follows:
Step one: according to weight proportion of the present invention, becomes medicated bag by Semen Ziziphi Spinosae, Fructus Lycii, Semen Coicis bundle, is put in water and soaks about 45 minutes, filters, for subsequent use;
Step 2: by weight proportion of the present invention, take Poria, Cornu Cervi Degelatinatum, Rhizoma Atractylodis Macrocephalae (parched), Rhizoma dioscoreae (parched) pulverize be ground to 180 mesh sieves, for subsequent use;
Step 3: by weight proportion of the present invention, take Carapax et Plastrum Testudinis put into marmite add step one soak after remain cold water, exceed powder 3 ~ 4 centimetres, after being fried boiling with high heat, again with 30 minutes at a simmer, filter, obtain filtrate, in residue medicinal residues, add the water of 4 cm, add medicated bag in Radix Pseudostellariae, Radix Scutellariae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Polygalae, Placenta Hominis, Rhizoma Phragmitis, Radix Puerariae, Radix Platycodonis, Radix Rubiae, Radix Saposhnikoviae, the Rhizoma Anemarrhenae and step one, decoct 40 minutes, finally add Herba Agrimoniae and decoct 20 minutes, filter, waste, for subsequent use;
Step 4: twice filtrate in step 3 is merged, adds the powder in step 2 while hot, stir, both control of the present invention decoction lungy.
Medicine of the present invention has effects such as mending strengthening spleen and lung, dampness diuretic, nourishing YIN and supplementing blood, and control takes into account, successful, cheap, easy to use, have no side effect, the mode that this Chinese medicine preparation adopts is treated and can be reduced the damage of Western medicine to human liver renal function, avoid the drug resistance of antibacterial, alleviate the slight illness of patient.According to clinical 196 routine patient view statistics, to use after a course for the treatment of of medicine of the present invention total effective rate 96% after 89.8%, two courses for the treatment of of total effective rate.
Detailed description of the invention
Embodiment one, Radix Pseudostellariae 4 parts, Rhizoma Atractylodis Macrocephalae (parched) 10 parts, Rhizoma dioscoreae (parched) 10 parts, 10 parts, Poria, the Radix Astragali 19 parts, Radix Angelicae Sinensis 13 parts, the Radix Paeoniae Alba 7 parts, Radix Rehmanniae Preparata 10 parts, Semen Ziziphi Spinosae 13 parts, Radix Polygalae 7 parts, Fructus Lycii 10 parts, Carapax et Plastrum Testudinis 7 parts, Placenta Hominis 5 parts, Cornu Cervi Degelatinatum 7 parts, Rhizoma Phragmitis 15 parts, Radix Puerariae 7 parts, Radix Platycodonis 10 parts, Semen Coicis 19 parts, Herba Agrimoniae 13 parts, 7 parts, Radix Rubiae, Radix Saposhnikoviae 5 parts, the Rhizoma Anemarrhenae 4 parts.
Embodiment two, Radix Pseudostellariae 9 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Rhizoma dioscoreae (parched) 15 parts, 15 parts, Poria, the Radix Astragali 24 parts, Radix Angelicae Sinensis 18 parts, the Radix Paeoniae Alba 12 parts, Radix Rehmanniae Preparata 15 parts, Semen Ziziphi Spinosae 18 parts, Radix Polygalae 12 parts, Fructus Lycii 15 parts, Carapax et Plastrum Testudinis 12 parts, Placenta Hominis 10 parts, Cornu Cervi Degelatinatum 12 parts, Rhizoma Phragmitis 20 parts, Radix Puerariae 12 parts, Radix Platycodonis 15 parts, Semen Coicis 24 parts, Herba Agrimoniae 18 parts, 12 parts, Radix Rubiae, Radix Saposhnikoviae 10 parts, the Rhizoma Anemarrhenae 9 parts.
Embodiment three, Radix Pseudostellariae 14 parts, Rhizoma Atractylodis Macrocephalae (parched) 20 parts, Rhizoma dioscoreae (parched) 20 parts, 20 parts, Poria, the Radix Astragali 29 parts, Radix Angelicae Sinensis 23 parts, the Radix Paeoniae Alba 17 parts, Radix Rehmanniae Preparata 20 parts, Semen Ziziphi Spinosae 23 parts, Radix Polygalae 17 parts, Fructus Lycii 20 parts, Carapax et Plastrum Testudinis 17 parts, Placenta Hominis 15 parts, Cornu Cervi Degelatinatum 17 parts, Rhizoma Phragmitis 25 parts, Radix Puerariae 17 parts, Radix Platycodonis 20 parts, Semen Coicis 29 parts, Herba Agrimoniae 23 parts, 17 parts, Radix Rubiae, Radix Saposhnikoviae 15 parts, the Rhizoma Anemarrhenae 14 parts.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept out-patient 196 example for medical treatment.Patient is divided into observation group and matched group at random, wherein male 108 example, women 88 example, M-F 1.2:1, max age 66 years old, minimal ages 15 years old, 37 years old mean age.The course of disease time is not etc.
Two, Therapeutic Method
Observation group is according to Medications Example two of the present invention, and the decoction that preferred preparation method is made, sooner or later respectively once, and decoction being taken warmly, 10 days courses for the treatment of.
Three, efficacy assessment standard
1, cure: clinical symptoms lungy disappears completely, and the tuberculosis symptom manifested everywhere disappears all completely, place's enlargements such as bone, joint, lymph disappear, and routine urinalysis etc. check normal.
2, take a turn for the better: clinical symptoms lungy is alleviated gradually, and the tuberculosis symptom manifested everywhere is controlled.
3, do not heal: control lungy is without any effect.
Four, therapeutic outcome statistics
According to statistical result showed, Chinese medicine of the present invention has good clinical effectiveness on tuberculosis prevention and treatment, effectively can improve the cure rate for the treatment of, is worth promoting in clinical practice.
Model case and curative effect:
Case one, fourth, female, 41 years old, suffer from pulmonary tuberculosis, multi-treatment poor effect, once treated with medicines such as rifampicin, the state of an illness always repeatedly, went to a doctor afterwards, adopts case two method of the present invention by here, after patient takes two courses for the treatment of, symptom alleviates substantially, and cough, spitting of blood number of times reduce, focal calcification, continue again to take two courses for the treatment of, patient's readme symptom all disappears, and removes examination in hospital, indices all shows normally, recovery from illness.
Case two, Zhang, man, 50 years old, patient suffered from tuberculosis of spine, recent patient's aggravation, there is cold abscess in inboard leg, has the phenomenon come to a head, patient is at hospitalize one wheat harvesting period, and curative effect is not obvious, and went to a doctor in here afterwards, adopt case two method of the present invention, after patient takes 3 courses for the treatment of, patient's readme symptom obviously alleviates, go to hospital to check, sinus tract heals, and the other tissue mass of X-ray vertebra disappears, vertebral bone increase in density, presents Bony union, recovery from illness.

Claims (4)

1. the Chinese medicine preparation for tuberculosis prevention and treatment, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Radix Pseudostellariae 4-14 part, Rhizoma Atractylodis Macrocephalae (parched) 10-20 part, Rhizoma dioscoreae (parched) 10-20 part, Poria 10-20 part, Radix Astragali 19-29 part, Radix Angelicae Sinensis 13-23 part, Radix Paeoniae Alba 7-17 part, Radix Rehmanniae Preparata 10-20 part, Semen Ziziphi Spinosae 13-23 part, Radix Polygalae 7-17 part, Fructus Lycii 10-20 part, Carapax et Plastrum Testudinis 7-17 part, Placenta Hominis 5-15 part, Cornu Cervi Degelatinatum 7-17 part, Rhizoma Phragmitis 15-25 part, Radix Puerariae 7-17 part, Radix Platycodonis 10-20 part, Semen Coicis 19-29 part, Herba Agrimoniae 13-23 part, Radix Rubiae 7-17 part, Radix Saposhnikoviae 5-15 part, Rhizoma Anemarrhenae 4-14 part.
2. the Chinese medicine preparation for tuberculosis prevention and treatment according to claims 1, it is characterized in that, be made up of the medicine of following weight portion: Radix Pseudostellariae 9 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Rhizoma dioscoreae (parched) 15 parts, 15 parts, Poria, the Radix Astragali 24 parts, Radix Angelicae Sinensis 18 parts, the Radix Paeoniae Alba 12 parts, Radix Rehmanniae Preparata 15 parts, Semen Ziziphi Spinosae 18 parts, Radix Polygalae 12 parts, Fructus Lycii 15 parts, Carapax et Plastrum Testudinis 12 parts, Placenta Hominis 10 parts, Cornu Cervi Degelatinatum 12 parts, Rhizoma Phragmitis 20 parts, Radix Puerariae 12 parts, Radix Platycodonis 15 parts, Semen Coicis 24 parts, Herba Agrimoniae 18 parts, 12 parts, Radix Rubiae, Radix Saposhnikoviae 10 parts, the Rhizoma Anemarrhenae 9 parts.
3. the Chinese medicine preparation for tuberculosis prevention and treatment according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is decoction.
4. for a preparation method for the Chinese medicine preparation of tuberculosis prevention and treatment, it is characterized in that, preparation method is as follows: step one: according to weight proportion of the present invention, Semen Ziziphi Spinosae, Fructus Lycii, Semen Coicis bundle are become medicated bag, be put in water and soak about 45 minutes, filter, for subsequent use; Step 2: by weight proportion of the present invention, take Poria, Cornu Cervi Degelatinatum, Rhizoma Atractylodis Macrocephalae (parched), Rhizoma dioscoreae (parched) pulverize be ground to 180 mesh sieves, for subsequent use; Step 3: by weight proportion of the present invention, take Carapax et Plastrum Testudinis put into marmite add step one soak after remain cold water, exceed powder 3 ~ 4 centimetres, after being fried boiling with high heat, again with 30 minutes at a simmer, filter, obtain filtrate, in residue medicinal residues, add the water of 4 cm, add medicated bag in Radix Pseudostellariae, Radix Scutellariae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Rehmanniae Preparata, Radix Polygalae, Placenta Hominis, Rhizoma Phragmitis, Radix Puerariae, Radix Platycodonis, Radix Rubiae, Radix Saposhnikoviae, the Rhizoma Anemarrhenae and step one, decoct 40 minutes, finally add Herba Agrimoniae and decoct 20 minutes, filter, waste, for subsequent use; Step 4: twice filtrate in step 3 is merged, adds the powder in step 2 while hot, stir, both control of the present invention decoction lungy.
CN201510029142.5A 2015-01-21 2015-01-21 Traditional Chinese medicine preparation for preventing and treating tuberculosis and preparation method thereof Pending CN104524343A (en)

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