CN104521942B - A kind of Gentle Repose agent - Google Patents
A kind of Gentle Repose agent Download PDFInfo
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- CN104521942B CN104521942B CN201410814315.XA CN201410814315A CN104521942B CN 104521942 B CN104521942 B CN 104521942B CN 201410814315 A CN201410814315 A CN 201410814315A CN 104521942 B CN104521942 B CN 104521942B
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Abstract
The present invention relates to corrosion-resistant field, more specifically a kind of Gentle Repose agent, be made up of following component by weight: formaldehyde, alcohol, glycerine, hexadecyltrimethylammonium chloride, isothiazolinone, water, vitamin C, tartaric acid, Chinese medicine additive, the invention has the beneficial effects as follows: by adding Chinese herbal medicine formula, and vitamin C with matching and tartaric acid, substantially increase the anti-oxidant of remains and antibacterial ability, effectively improve corrosion-resistant effect, in Chinese herbal medicine, the composition of various complexity passes through dilution and digestion simultaneously, greatly reduce the toxicity of formaldehyde, improve the safety of preservative, with the addition of hexadecyltrimethylammonium chloride and isothiazolinone, both all have bactericidal effect, but its effect mainly played is composition activation, especially the trimethyl ammonium chloride in hexadecyltrimethylammonium chloride has higher polarity, substantially increase the activity of the active ingredient in Chinese herbal medicine, thus further increase corrosion-resistant effect.
Description
Technical field
The present invention relates to corrosion-resistant field, more specifically a kind of Gentle Repose agent.
Background technology
The anticorrosion concern being more and more subject to each side of Gentle Repose especially human body remains, preservative conventional both at home and abroad is at present formalin, its main component is formaldehyde, in Gentle Repose practice is preserved, antiseptic effect has been possessed strong containing formaldehyde and antiseptic liquid, easy to use, the advantage such as cheap, impregnating fluid containing formaldehyde is strong to remains tissue infiltration power, convergent force is little, in maintenance remains morphologic localization and maintenance skin color, effect is better, pot-life is comparatively stable permanent, but formaldehyde is the easy hardening embrittlement of fixing organization often, meat fiber is easily pulled off, there is strong impulse taste, therefore the research for formaldehyde and antiseptic gets more and more, and to address this problem at present conventional method be find the substitute of formaldehyde, as ethanol, the alcohols organic reagents such as propyl alcohol, but antiseptic effect does not all reach the effect of formaldehyde, as the short-term Gentle Repose agent that application discloses a kind of low toxic and environment-friendly that application number is 201010546655.0, it is the ethanol of 60-75% primarily of volume ratio, 1 of 5-20, 2-propane diols, the organic acid of 3-15%, the essence of 0-0.3%, the distilled water of 10-40% and weight ratio are the nipagin esters of 0.2-10%, the thymol of 0.3-3%, the mannitol (or D-glucitol) of 0.5-3%, 0.05-0.5% low toxicity slaine is formed, above-mentioned patent application is based on alcohols, not containing formaldehyde, electrodeless oxide and organic oxygen compound, formaldehydeless penetrating odor, to the mankind and environmental injury little, low toxic and environment-friendly, and preparation is had a holiday or vacation simple, raw material is easy to get, but it is only only applicable to the Gentle Repose of short-term or the preservation of sample, poor for long antiseptic effect, do not find the substitute of good formaldehyde at present.
Summary of the invention
Goal of the invention of the present invention is the main component providing a kind of practical formaldehyde as preservative, and adds corresponding auxiliary material and medicinal herb components, greatly reduces the toxicity that formaldehyde brings while effectively improving antiseptic effect.
The present invention is achieved by the following technical solutions:
A kind of Gentle Repose agent, is made up of following component by weight:
Formaldehyde 5-15 part
Alcohol 5-15 part
Glycerine 25-85 part
Hexadecyltrimethylammonium chloride 2-8 part
Isothiazolinone 2-8 part
Water 30-50 part
Vitamin C 1-3 part
Tartaric acid 2-5 part
Chinese medicine additive 3-15 part.
Above-mentioned Chinese medicine additive is made up of following component by weight: Herba Andrographitis 6-15 part, broomwort 6-15 part, golden cypress 3-8 part, root of large-flowered skullcap 3-8 part, downy rosemyrtle root 3-8 part, bush 3-8 part, Asian puccoon 3-8 part, cordate houttuynia 2-6 part, Chinese violet 2-6 part, climbing groundsel 2-6 part, oldenlandia diffusa 2-6 part, reticulate millettia 2-6 part, celastrus orbiculatus 2-6 part, bark of official magnolia 2-6 part, blackberry lily 2-6 part.
Optimize, foregoing preservatives is made up of following component by weight
Formaldehyde 8-12 part
Alcohol 8-12 part
Glycerine 50-80 part
Hexadecyltrimethylammonium chloride 3-5 part
Isothiazolinone 3-5 part
Water 40-50 part
Catergen part
Tartaric acid 3-4 part
Chinese medicine additive 5-10 part.
Above-mentioned Chinese medicine additive is made up of following component by weight: Herba Andrographitis 8-12 part, broomwort 8-12 part, golden cypress 4-6 part, root of large-flowered skullcap 4-6 part, downy rosemyrtle root 4-6 part, bush 4-6 part, Asian puccoon 4-6 part, cordate houttuynia 3-5 part, Chinese violet 3-5 part, climbing groundsel 3-5 part, oldenlandia diffusa 3-5 part, reticulate millettia 3-5 part, celastrus orbiculatus 3-5 part, bark of official magnolia 3-5 part, blackberry lily 3-5 part.
As wherein a kind of optimal case, foregoing preservatives is made up of following component by weight
10 parts, formaldehyde
Alcohol 10 parts
Glycerine 70 parts
Hexadecyltrimethylammonium chloride 4 parts
Isothiazolinone 4 parts
45 parts, water
Catergen part
3 parts, tartaric acid
Chinese medicine additive 8 parts.
Above-mentioned Chinese medicine additive is made up of following component by weight: Herba Andrographitis 10 parts, broomwort 10 parts, golden cypress 5 parts, the root of large-flowered skullcap 5 parts, downy rosemyrtle root 5 parts, bush 5 parts, Asian puccoon 5 parts, cordate houttuynia 4 parts, Chinese violet 4 parts, climbing groundsel 4 parts, oldenlandia diffusa 4 parts, reticulate millettia 4 parts, celastrus orbiculatus 4 parts, the bark of official magnolia 4 parts, blackberry lily 4 parts.
The preparation method of above-mentioned Chinese medicine additive comprises the steps: Herba Andrographitis, broomwort, golden cypress, the root of large-flowered skullcap, downy rosemyrtle root, bush, Asian puccoon, cordate houttuynia, Chinese violet, climbing groundsel, oldenlandia diffusa, reticulate millettia, celastrus orbiculatus, the bark of official magnolia, blackberry lily to clean, put into marmite and add the water of traditional Chinese medicine 5 times of quality, intense fire transfers slow fire to and keeps boiling decoction 3 hours after decocting 2 hours, cooling, filtering and be concentrated into relative density 60 DEG C time is 1.06-1.10, sterilization after cooling.
After above-mentioned Chinese medicine additive is concentrated, 60 DEG C time, relative density is 1.08.
The invention has the beneficial effects as follows: by adding Chinese herbal medicine formula, and vitamin C with matching and tartaric acid, substantially increase the anti-oxidant of remains and antibacterial ability, effectively improve corrosion-resistant effect, in Chinese herbal medicine, the composition of various complexity passes through dilution and digestion simultaneously, greatly reduce the toxicity of formaldehyde, improve the safety of preservative, and the application also added hexadecyltrimethylammonium chloride and isothiazolinone, both all have bactericidal effect, but the effect that in the application, it mainly plays is composition activation, especially the trimethyl ammonium chloride in hexadecyltrimethylammonium chloride has higher polarity, substantially increase the activity of the active ingredient in Chinese herbal medicine, thus further increase corrosion-resistant effect.
Embodiment
Below in conjunction with specific embodiment, the present invention will be further described, so that those skilled in the art better can understand the present invention, but therefore do not limit the present invention.
Embodiment 1
A kind of Gentle Repose agent, is made up of following component by weight:
5 parts, formaldehyde
Alcohol 5 parts
Glycerine 25 parts
Hexadecyltrimethylammonium chloride 2 parts
Isothiazolinone 2 parts
30 parts, water
Vitamin C 1 part
2 parts, tartaric acid
Chinese medicine additive 3 parts.
Above-mentioned Chinese medicine additive is made up of following component by weight: Herba Andrographitis 6 parts, broomwort 6 parts, golden cypress 3 parts, the root of large-flowered skullcap 3 parts, downy rosemyrtle root 3 parts, bush 3 parts, Asian puccoon 3 parts, cordate houttuynia 2 parts, Chinese violet 2 parts, climbing groundsel 2 parts, oldenlandia diffusa 2 parts, reticulate millettia 2 parts, celastrus orbiculatus 2 parts, the bark of official magnolia 2 parts, blackberry lily 2 parts.
Embodiment 2
A kind of preservative, is made up of following component by weight
10 parts, formaldehyde
Alcohol 10 parts
Glycerine 70 parts
Hexadecyltrimethylammonium chloride 4 parts
Isothiazolinone 4 parts
45 parts, water
Catergen part
3 parts, tartaric acid
Chinese medicine additive 8 parts.
Above-mentioned Chinese medicine additive is made up of following component by weight: Herba Andrographitis 10 parts, broomwort 10 parts, golden cypress 5 parts, the root of large-flowered skullcap 5 parts, downy rosemyrtle root 5 parts, bush 5 parts, Asian puccoon 5 parts, cordate houttuynia 4 parts, Chinese violet 4 parts, climbing groundsel 4 parts, oldenlandia diffusa 4 parts, reticulate millettia 4 parts, celastrus orbiculatus 4 parts, the bark of official magnolia 4 parts, blackberry lily 4 parts.
Embodiment 3
A kind of Gentle Repose agent, is made up of following component by weight:
15 parts, formaldehyde
Alcohol 15 parts
Glycerine 85 parts
Hexadecyltrimethylammonium chloride 8 parts
Isothiazolinone 8 parts
50 parts, water
Vitamin C 3 parts
5 parts, tartaric acid
Chinese medicine additive 15 parts.
Above-mentioned Chinese medicine additive is made up of following component by weight: Herba Andrographitis 15 parts, broomwort 15 parts, golden cypress 8 parts, the root of large-flowered skullcap 8 parts, downy rosemyrtle root 8 parts, bush 8 parts, Asian puccoon 8 parts, cordate houttuynia 8 parts, Chinese violet 6 parts, climbing groundsel 6 parts, oldenlandia diffusa 6 parts, reticulate millettia 6 parts, celastrus orbiculatus 6 parts, the bark of official magnolia 6 parts, blackberry lily 6 parts.
Embodiment 4
A kind of preservative, is made up of following component by weight
10 parts, formaldehyde
Alcohol 10 parts
Glycerine 70 parts
Hexadecyltrimethylammonium chloride 4 parts
Isothiazolinone 4 parts
45 parts, water
Catergen part
3 parts, tartaric acid.
Embodiment 5
A kind of preservative, is made up of following component by weight
10 parts, formaldehyde
Alcohol 10 parts
Glycerine 70 parts
Hexadecyltrimethylammonium chloride 4 parts
Isothiazolinone 4 parts
45 parts, water
Chinese medicine additive 8 parts.
Above-mentioned Chinese medicine additive is made up of following component by weight: Herba Andrographitis 10 parts, broomwort 10 parts, golden cypress 5 parts, the root of large-flowered skullcap 5 parts, downy rosemyrtle root 5 parts, bush 5 parts, Asian puccoon 5 parts, cordate houttuynia 4 parts, Chinese violet 4 parts, climbing groundsel 4 parts, oldenlandia diffusa 4 parts, reticulate millettia 4 parts, celastrus orbiculatus 4 parts, the bark of official magnolia 4 parts, blackberry lily 4 parts.
Embodiment 6
A kind of preservative, is made up of following component by weight
10 parts, formaldehyde
Alcohol 10 parts
Glycerine 70 parts
45 parts, water
Catergen part
3 parts, tartaric acid
Chinese medicine additive 8 parts.
Above-mentioned Chinese medicine additive is made up of following component by weight: Herba Andrographitis 10 parts, broomwort 10 parts, golden cypress 5 parts, the root of large-flowered skullcap 5 parts, downy rosemyrtle root 5 parts, bush 5 parts, Asian puccoon 5 parts, cordate houttuynia 4 parts, Chinese violet 4 parts, climbing groundsel 4 parts, oldenlandia diffusa 4 parts, reticulate millettia 4 parts, celastrus orbiculatus 4 parts, the bark of official magnolia 4 parts, blackberry lily 4 parts.
The preparation method of the Chinese medicine additive of above-described embodiment 1-3 and embodiment 5 and 6 is as follows: Herba Andrographitis, broomwort, golden cypress, the root of large-flowered skullcap, downy rosemyrtle root, bush, Asian puccoon, cordate houttuynia, Chinese violet, climbing groundsel, oldenlandia diffusa, reticulate millettia, celastrus orbiculatus, the bark of official magnolia, blackberry lily are cleaned, put into marmite and add the water of traditional Chinese medicine 5 times of quality, intense fire transfers slow fire to and keeps boiling decoction 3 hours after decocting 2 hours, cooling, filtering and be concentrated into relative density 60 DEG C time is 1.08, sterilization after cooling.
Testing experiment
Mouse experiment, first after getting the Su Mian Xin veterinary drug execution of the practical 0.1ml/Kg of mouse of 6 figure and features such as weight, bodily form feature similarities, and impregnating fluid prepared by above-described embodiment 1-6 is pressed 15ml/100g and inject in Mice Body, and be placed on shady and cool ventilation drying place, under room temperature, (14-18 DEG C) deposits, and respectively with within 3,7,15,30,45,60 days, observe the configuration of surface of mouse and record the smell that mouse distributes, record sees the following form.
Claims (4)
1. a Gentle Repose agent, is characterized in that: be made up of following component by weight:
Formaldehyde 5-15 part
Alcohol 5-15 part
Glycerine 25-85 part
Hexadecyltrimethylammonium chloride 2-8 part
Isothiazolinone 2-8 part
Water 30-50 part
Vitamin C 1-3 part
Tartaric acid 2-5 part
Chinese medicine additive 3-15 part;
Described Chinese medicine additive is made up of following component by weight: Herba Andrographitis 6-15 part, broomwort 6-15 part, golden cypress 3-8 part, root of large-flowered skullcap 3-8 part, downy rosemyrtle root 3-8 part, bush 3-8 part, Asian puccoon 3-8 part, cordate houttuynia 2-6 part, Chinese violet 2-6 part, climbing groundsel 2-6 part, oldenlandia diffusa 2-6 part, reticulate millettia 2-6 part, celastrus orbiculatus 2-6 part, bark of official magnolia 2-6 part, blackberry lily 2-6 part;
The preparation method of described Chinese medicine additive comprises the steps: Herba Andrographitis, broomwort, golden cypress, the root of large-flowered skullcap, downy rosemyrtle root, bush, Asian puccoon, cordate houttuynia, Chinese violet, climbing groundsel, oldenlandia diffusa, reticulate millettia, celastrus orbiculatus, the bark of official magnolia, blackberry lily to clean, put into marmite and add the water of traditional Chinese medicine 5 times of quality, intense fire transfers slow fire to and keeps boiling decoction 3 hours after decocting 2 hours, cooling, filtering and be concentrated into relative density 60 DEG C time is 1.06-1.10, sterilization after cooling.
2. a kind of Gentle Repose agent according to claim 1, is characterized in that: described preservative is made up of following component by weight:
Formaldehyde 8-12 part
Alcohol 8-12 part
Glycerine 50-80 part
Hexadecyltrimethylammonium chloride 3-5 part
Isothiazolinone 3-5 part
Water 40-50 part
Catergen part
Tartaric acid 3-4 part
Chinese medicine additive 5-10 part;
Described Chinese medicine additive is made up of following component by weight: Herba Andrographitis 8-12 part, broomwort 8-12 part, golden cypress 4-6 part, root of large-flowered skullcap 4-6 part, downy rosemyrtle root 4-6 part, bush 4-6 part, Asian puccoon 4-6 part, cordate houttuynia 3-5 part, Chinese violet 3-5 part, climbing groundsel 3-5 part, oldenlandia diffusa 3-5 part, reticulate millettia 3-5 part, celastrus orbiculatus 3-5 part, bark of official magnolia 3-5 part, blackberry lily 3-5 part; The preparation method of described Chinese medicine additive comprises the steps: Herba Andrographitis, broomwort, golden cypress, the root of large-flowered skullcap, downy rosemyrtle root, bush, Asian puccoon, cordate houttuynia, Chinese violet, climbing groundsel, oldenlandia diffusa, reticulate millettia, celastrus orbiculatus, the bark of official magnolia, blackberry lily to clean, put into marmite and add the water of traditional Chinese medicine 5 times of quality, intense fire transfers slow fire to and keeps boiling decoction 3 hours after decocting 2 hours, cooling, filtering and be concentrated into relative density 60 DEG C time is 1.06-1.10, sterilization after cooling.
3. a kind of Gentle Repose agent according to claim 2, is characterized in that: described preservative is made up of following component by weight
10 parts, formaldehyde
Alcohol 10 parts
Glycerine 70 parts
Hexadecyltrimethylammonium chloride 4 parts
Isothiazolinone 4 parts
45 parts, water
Catergen part
3 parts, tartaric acid
Chinese medicine additive 8 parts;
Described Chinese medicine additive is made up of following component by weight: Herba Andrographitis 10 parts, broomwort 10 parts, golden cypress 5 parts, the root of large-flowered skullcap 5 parts, downy rosemyrtle root 5 parts, bush 5 parts, Asian puccoon 5 parts, cordate houttuynia 4 parts, Chinese violet 4 parts, climbing groundsel 4 parts, oldenlandia diffusa 4 parts, reticulate millettia 4 parts, celastrus orbiculatus 4 parts, the bark of official magnolia 4 parts, blackberry lily 4 parts; The preparation method of described Chinese medicine additive comprises the steps: Herba Andrographitis, broomwort, golden cypress, the root of large-flowered skullcap, downy rosemyrtle root, bush, Asian puccoon, cordate houttuynia, Chinese violet, climbing groundsel, oldenlandia diffusa, reticulate millettia, celastrus orbiculatus, the bark of official magnolia, blackberry lily to clean, put into marmite and add the water of traditional Chinese medicine 5 times of quality, intense fire transfers slow fire to and keeps boiling decoction 3 hours after decocting 2 hours, cooling, filtering and be concentrated into relative density 60 DEG C time is 1.06-1.10, sterilization after cooling.
4. according to a kind of Gentle Repose agent in claim 1-3 described in any one, it is characterized in that: after described Chinese medicine additive is concentrated, 60 DEG C time, relative density is 1.08.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410814315.XA CN104521942B (en) | 2014-12-24 | 2014-12-24 | A kind of Gentle Repose agent |
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|---|---|---|---|
| CN201410814315.XA CN104521942B (en) | 2014-12-24 | 2014-12-24 | A kind of Gentle Repose agent |
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| Publication Number | Publication Date |
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| CN104521942A CN104521942A (en) | 2015-04-22 |
| CN104521942B true CN104521942B (en) | 2016-04-27 |
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| CN201410814315.XA Expired - Fee Related CN104521942B (en) | 2014-12-24 | 2014-12-24 | A kind of Gentle Repose agent |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104798768A (en) * | 2015-04-29 | 2015-07-29 | 合肥金域医学检验所有限公司 | Preservation and treatment solution of in-vitro specimen for medical research |
| CN111771867A (en) * | 2020-07-13 | 2020-10-16 | 许昌学院 | Preservative for biological dissection experiments and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1199561C (en) * | 2001-10-30 | 2005-05-04 | 上海方富科技有限公司 | A kind of preservative and its prepn. method |
| JP2008137909A (en) * | 2006-11-30 | 2008-06-19 | Tetsuji Kondo | Mixture for embalming corpse, method for preparing the same and method for applying the embalming mixture to corpse and treating the corpse therewith |
| CN101496511A (en) * | 2008-01-31 | 2009-08-05 | 任祖翰 | Antisepsis composition for remains as well as preparation method and application |
| CN102524240B (en) * | 2010-12-10 | 2014-10-29 | 民政部一零一研究所 | Efficient and environment-friendly remains preservative and application thereof |
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