CN106821844B - A kind of composition with anti-mite and delaying senility function and the skin care item comprising the composition - Google Patents

A kind of composition with anti-mite and delaying senility function and the skin care item comprising the composition Download PDF

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Publication number
CN106821844B
CN106821844B CN201710046291.1A CN201710046291A CN106821844B CN 106821844 B CN106821844 B CN 106821844B CN 201710046291 A CN201710046291 A CN 201710046291A CN 106821844 B CN106821844 B CN 106821844B
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parts
composition
mite
extract
delaying senility
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CN106821844A (en
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张淑云
张灿海
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Guangzhou Yilumei Cosmetics Co Ltd
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Guangzhou Yilumei Cosmetics Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/738Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/965Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of composition with anti-mite and delaying senility function, the composition include the ingredient of following parts by weight: 5~10 parts of phellodendron extract, 20~30 parts of mung bean flour, 5~15 parts of grape seed extract, 40~50 parts of deep-sea mud.Composition material of the present invention be entirely it is pure natural, to skin without any stimulation and toxic side effect, mutually cooperateed between each ingredient, it can be with bactericidal antiphlogistic, improve skin function and reaches preferable delaying senility function while improving skin antimite ability function.

Description

A kind of composition with anti-mite and delaying senility function and the shield comprising the composition Skin product
Technical field
The present invention relates to a kind of composition, especially a kind of composition with anti-mite and delaying senility function and include this The skin care item of composition.
Background technique
Acarid is widely present in crowd, the disintegration after acarid body distorted proliferation hyperplasia, after polypide itself and polypide death Product can make part inflammation occur the mechanical irritation of part and its chemical action of metabolite.Due to mite in hair follicle not Disconnected breeding and destruction tissue, hair follicle and sebaceous glands take the shape of a bag expansion, extension or even hypertrophy over time, form pachydermatosis.Have Data shows that pathological section confirms that Demodex Parasitized is one of origin cause of formation of brandy nose.Due to acarid can also usually pass in and out hair follicle and Sebaceous glands also creates condition for bacterium intrusion, can cause the generation of acne and furuncle.
Mostly while pressing down mite, the side effect of irritating skin uses presently commercially available anti-mite suppression mite product for a long time Although can alleviate the symptoms such as the acne as caused by acarid, brandy nose, skin is easy to tarnish, flexibility decrease, rapidly Aging.
Summary of the invention
Based on this, provided it is an object of the invention to overcome in place of above-mentioned the deficiencies in the prior art it is a kind of have anti-mite and The composition of delaying senility function.
To achieve the above object, the technical solution used in the present invention are as follows: a kind of with anti-mite and delaying senility function Composition, the composition include the ingredient of following parts by weight: 5~10 parts of phellodendron extract, 20~30 parts of mung bean flour, grape pip 5~15 parts of extract, 40~50 parts of deep-sea mud.
Composition material of the present invention be entirely it is pure natural, to skin without any stimulation and toxic side effect, each ingredient Between mutually cooperate with, while anti-mite, reach preferable delaying senility function, the effect of specific ingredient is as follows:
Phellodendron extract is the extract extracted from the bark of rutaceae Cortex Phellodendri or phellodendron bark, is contained in Cortex Phellodendri There are the alkaloids such as a large amount of Berberine hydrochlorides, jateorrhizine, phellodendrine, separately containing obakunone, obakulactone etc., has in document report Cortex Phellodendri The content of Berberine hydrochloride is about 1.4%~5.8%, and phellodendron extract has heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment, resists Bacterium and other effects.Phellodendron extract is used in cosmetics by existing document report, is enhanced the antibacterial of cosmetics, antiallergy, anti-inflammatory, is disappeared Except eczema and other effects.
Mung bean flour brightens, desalinates because it contains the minerals such as a large amount of protein, B family vitamin and calcium, phosphorus, iron Spot, removal cutin, inhibits the effect of whelk at cleaning skin, is suitble to fat secretion excessive or dark sore skin uses, and have There are good antiphlogistic antibacterial and clean function.
Grape seed extract is one of most efficient antioxidant of the plant origin found so far, is tested in vivo and in vitro The antioxidant effect for showing grape seed extract " procyanidine OPC " is 50-70 times of vitamin C and vitamin E.Superpower Anti-oxidant efficiency has the strength effect removing free radical, improving the immunity of the human body.Proflavanol (Grape Seed Extract) containing abundant bioflavonoid, be strength essence molecule, for free radical resisting (free radical) and maintenance microfilament blood The health of pipe.(free radical is the one of the major reasons for causing aging and many diseases, the aging of tool estimation about 80%-90% Property, degenerative disorders it is all related with free radical, so, grape seed extract is anti-oxidant to human body, improve immunity have it is splendid Effect.
Deep-sea mud: containing minerals, applies and lives skin in face's energy " absorption " " bored ", the solidified oil being easier on " removal " skin Rouge, dirt, deep layer cleaning skin promote metabolism.
Preferably, the composition includes the ingredient of following parts by weight: 7~9 parts of phellodendron extract, mung bean flour 23~28 Part, 7~12 parts of grape seed extract, 43~48 parts of deep-sea mud.
It is highly preferred that the composition includes the ingredient of following parts by weight: 8 parts of phellodendron extract, 25 parts of mung bean flour, grape 10 parts of seed extract, 45 parts of deep-sea mud.
Inventor attempts by a large amount of, has been surprisingly found that the ingredient of above-mentioned parts by weight, can play better synergistic effect, is killing Bacterium anti-inflammatory improves skin function, while improving skin antimite ability function, reaches better delaying senility function.
Preferably, the composition includes the ingredient of following parts by weight: 5~10 parts of Radix et Caulis Opuntiae Dillenii extract, astaxanthin 3~4 Part.
Vitamin C rich in, vitamin E, fatty acid in Radix et Caulis Opuntiae Dillenii extract can be removed effectively and be inhibited freely Base can nourish skin with deep layer, and moisturizing water lock increases moisture of skin, rests on moisture in skin for a long time, enhance skin day Right water holding capacity reaches the tender state of oil-control moisturizing, water, while can also anti-inflammatory anti-acne, wrinkle reduction.
Astaxanthin is a kind of terpenes unsaturated compounds, and class belongs to lutein class-beta carotene family.It is deposited extensively It is in living nature, especially content is higher in the feather of shrimp, crab, fish, frond, yeast and birds.Astaxanthin is natural resists Oxidant, can oxygen radical in effective scavenger-cell, prevent tissue, cell, DNA to be oxidized damage, it is referred to as " super Vitamin E ".Studies have shown that the antioxidant activity of astaxanthin is 10 times of beta carotene, 17 times of grape pip, lipoic acid 75 times, 200 times of lutein, 1000 times, 800 times of Co-Q10 of vitamin E.The aging of human body, mainly due to free radical Caused oxidation institute is extremely.And the molecular configuration that astaxanthin is special, human body cell outer wall can be passed through, in direct scavenger-cell Oxygen radical enhances cytothesis ability, maintains function of human body balance and reduces the accumulation of senile cell, protection is thin from inside to outside Born of the same parents and DNA health.
It is highly preferred that the composition includes the ingredient of following parts by weight: 8 parts of Radix et Caulis Opuntiae Dillenii extract, 3.5 parts of astaxanthin.
Preferably, the weight ratio of the mung bean flour, grape seed extract and deep-sea mud are as follows: mung bean flour: grape seed extract: Deep-sea mud=5:2:9.
Inventors be surprised to learn that each ingredient of above-mentioned weight ratio, can preferably cooperate, mutually cooperates with, reach more preferable Anti- mite and delaying senility function.
Preferably, the weight ratio of the astaxanthin and phellodendron extract are as follows: astaxanthin: phellodendron extract=7:16.
Inventors be surprised to learn that each ingredient of above-mentioned weight ratio, can preferably cooperate, mutually cooperates with, reach more preferable Anti- mite and delaying senility function.
It preferably, also include the hydroxyl fourth group-beta-cyclodextrin aqueous solution of 10~15 parts by weight, the hydroxyl fourth in the composition The mass percent of hydroxyl fourth group-beta-cyclodextrin is 10% in group-beta-cyclodextrin aqueous solution.
It, can be with prawn due to water-soluble smaller, the addition of the hydroxyl fourth group-beta-cyclodextrin aqueous solution of above-mentioned content of astaxanthin Green element and other water-soluble lesser ingredients are included well, on the one hand can be increased its water solubility, be improved raw material and utilize Rate;On the other hand it can increase its stability, reach preferable, more stable anti-mite and anti-aging effect.
Furthermore it is noted that in the present invention added each raw material and each extract component can be used it is existing often It is prepared with method, commercially available finished product can also be used.
Meanwhile the present invention also provides a kind of skin care item comprising above-mentioned composition.The skin care item are safe, mild, effective, With preferable anti-mite and function of delaying senility.
Preferably, the skin care item are facial mask.
Compared with the existing technology, the invention has the benefit that
Composition material of the present invention be entirely it is pure natural, it is specific to contain to skin without any stimulation and toxic side effect It is mutually cooperateed between each ingredient of amount ratio, mutual compatibility, in bactericidal antiphlogistic, improves skin function, improve skin antimite energy While power function, reach preferable anti-aging effect.
Specific embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention It is described further.
Embodiment 1
A kind of embodiment of composition of the present invention with anti-mite and delaying senility function combines described in the present embodiment Object includes the ingredient of following parts by weight:
8 parts of phellodendron extract, 25 parts of mung bean flour, 10 parts of grape seed extract, 45 parts of deep-sea mud, 8 parts of Radix et Caulis Opuntiae Dillenii extract, 3.5 parts of astaxanthin, the hydroxyl fourth group-beta-cyclodextrin aqueous solution (matter of hydroxyl fourth group-beta-cyclodextrin in hydroxyl fourth group-beta-cyclodextrin aqueous solution Measuring percentage is 10%) 13 parts.
A kind of facial mask comprising composition described in the present embodiment, also includes acceptable carrier and auxiliary material, and preparation method is adopted It is prepared with common process.
Embodiment 2
A kind of embodiment of composition of the present invention with anti-mite and delaying senility function combines described in the present embodiment Object includes the ingredient of following parts by weight:
5 parts of phellodendron extract, 20 parts of mung bean flour, 5 parts of grape seed extract, 40 parts of deep-sea mud, 5 parts of Radix et Caulis Opuntiae Dillenii extract, 3 parts of astaxanthin, the hydroxyl fourth group-beta-cyclodextrin aqueous solution (quality of hydroxyl fourth group-beta-cyclodextrin in hydroxyl fourth group-beta-cyclodextrin aqueous solution Percentage is 10%) 10 parts.
A kind of facial mask comprising composition described in the present embodiment, also includes acceptable carrier and auxiliary material, and preparation method is adopted It is prepared with common process.
Embodiment 3
A kind of embodiment of composition of the present invention with anti-mite and delaying senility function combines described in the present embodiment Object includes the ingredient of following parts by weight:
7 parts of phellodendron extract, 23 parts of mung bean flour, 7 parts of grape seed extract, 43 parts of deep-sea mud, 6 parts of Radix et Caulis Opuntiae Dillenii extract, 3.2 parts of astaxanthin, the hydroxyl fourth group-beta-cyclodextrin aqueous solution (matter of hydroxyl fourth group-beta-cyclodextrin in hydroxyl fourth group-beta-cyclodextrin aqueous solution Percentage is measured as 10%) 12 parts by weight.
A kind of facial mask comprising composition described in the present embodiment, also includes acceptable carrier and auxiliary material, and preparation method is adopted It is prepared with common process.
Embodiment 4
A kind of embodiment of composition of the present invention with anti-mite and delaying senility function combines described in the present embodiment Object includes the ingredient of following parts by weight:
9 parts of phellodendron extract, 28 parts of mung bean flour, 12 parts of grape seed extract, 48 parts of deep-sea mud, 7 parts of Radix et Caulis Opuntiae Dillenii extract, 3.8 parts of astaxanthin, the hydroxyl fourth group-beta-cyclodextrin aqueous solution (matter of hydroxyl fourth group-beta-cyclodextrin in hydroxyl fourth group-beta-cyclodextrin aqueous solution Measuring percentage is 10%) 14 parts.
A kind of facial mask comprising composition described in the present embodiment, also includes acceptable carrier and auxiliary material, and preparation method is adopted It is prepared with common process.
Embodiment 5
A kind of embodiment of composition of the present invention with anti-mite and delaying senility function combines described in the present embodiment Object includes the ingredient of following parts by weight:
10 parts of phellodendron extract, 30 parts of mung bean flour, 15 parts of grape seed extract, 50 parts of deep-sea mud, Radix et Caulis Opuntiae Dillenii extract 10 Part, 4 parts of astaxanthin, the hydroxyl fourth group-beta-cyclodextrin aqueous solution (matter of hydroxyl fourth group-beta-cyclodextrin in hydroxyl fourth group-beta-cyclodextrin aqueous solution Measuring percentage is 10%) 15 parts.
A kind of facial mask comprising composition described in the present embodiment, also includes acceptable carrier and auxiliary material, and preparation method is adopted It is prepared with common process.
Embodiment 6
Side effect test
100 20~45 years old women are randomly selected, using facial mask preparation-obtained in Examples 1 to 5, application method is With once before sleeping every night, after 3 months, discovery does not occur any side effect.Thus provable, it is of the present invention to have The facial mask that the composition of anti-mite and delaying senility function is prepared is without any side effects to skin.
Embodiment 7
Anti- mite measure of merit test
Test is divided into control group and experimental group, and experimental group is divided into 5 groups, and experimental group 1~5 is respectively made in Examples 1 to 5 Standby facial mask, control group are divided into 8 groups, and the weight fraction of component contained in the facial mask of control group 1~8 and each component is shown in Table 1:
1 control group facial mask ingredient of table
In control group and experimental group, every group randomly selects 100 and has the symptoms such as the acne as caused by acarid, brandy nose The face that is prepared respectively using Examples 1 to 5 as subjects, the subjects of experimental group 1~5 of 20~45 years old women Film, the facial mask that the subjects of control group 1~8 are prepared using control group 1~8 respectively, application method are every two days evenings Using once before sleeping, after 1 month, the remission effect situation of the symptoms such as the facial acne as caused by acarid, brandy nose is counted, The results are shown in Table 2.
The alleviation situation of the symptoms such as the facial acne as caused by acarid of table 2, brandy nose
As seen from Table 2, contained only in the facial mask of control group 1~6 mung bean flour, grape seed extract, three kinds of deep-sea mud at One or both of point, one of astaxanthin, phellodendron extract, control group 1~8 are contained only in the facial mask of control group 7~8 In facial mask do not have good anti-mite effect.And the facial mask of experimental group 1~5 contains mung bean flour, grape seed extract, deep-sea Three kinds of ingredients of mud and two kinds of astaxanthin, phellodendron extract ingredients have the anti-mite of good anti-mite effect, especially experimental group 1 Effect is best.Thus provable, in facial mask of the invention, three kinds of mung bean flour, grape seed extract, deep-sea mud ingredients have mutual The effect promote, mutually cooperateed with, two kinds of astaxanthin, phellodendron extract ingredients have the function of mutually promoting, mutually cooperate with, can Play significant anti-mite effect.
Embodiment 8
Anti-aging measure of merit
Test is divided into control group and experimental group, and experimental group is divided into 5 groups, and experimental group 1~5 is respectively made in Examples 1 to 5 Standby facial mask, control group are divided into 8 groups, and the weight fraction of component contained in the facial mask of control group 1~8 and each component is shown in Table 1:
In control group and experimental group, every group randomly selects 100 and has the skin as caused by acarid without elasticity, loses 20~45 years old women of gloss is prepared using Examples 1 to 5 respectively as subjects, the subjects of experimental group 1~5 Facial mask, the facial mask that the subjects of control group 1~8 are prepared using control group 1~8 respectively, application method be every two days Using once before sleeping at night, after 1 month, statistics skin of face elasticity, gloss situation, the results are shown in Table 3.
3 skin of face of table elasticity, gloss situation
As seen from Table 2, contained only in the facial mask of control group 1~6 mung bean flour, grape seed extract, three kinds of deep-sea mud at One or both of point, one of astaxanthin, phellodendron extract, control group 1~8 are contained only in the facial mask of control group 7~8 In facial mask do not have good anti-aging effect.And the facial mask of experimental group 1~5 contain mung bean flour, grape seed extract, Three kinds of ingredients of deep-sea mud and two kinds of astaxanthin, phellodendron extract ingredients have good anti-aging effect, especially experimental group 1 anti-aging effect is best.Thus provable, in facial mask of the invention, mung bean flour, grape seed extract, three kinds of deep-sea mud Ingredient has the function of mutually promoting, mutually cooperate with, and two kinds of astaxanthin, phellodendron extract ingredients, which have, mutually promotes, mutually assists Same effect, can play significant anti-aging effect.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than protects to the present invention The limitation of range is protected, although the invention is described in detail with reference to the preferred embodiments, those skilled in the art should Understand, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the essence of technical solution of the present invention And range.

Claims (9)

1. a kind of composition with anti-mite and delaying senility function, which is characterized in that the composition includes following parts by weight Ingredient: 5~10 parts of phellodendron extract, 20~30 parts of mung bean flour, 5~15 parts of grape seed extract, 40~50 parts of deep-sea mud;Institute State the weight ratio of mung bean flour, grape seed extract and deep-sea mud are as follows: mung bean flour: grape seed extract: deep-sea mud=5:2:9.
2. as described in claim 1 with the composition of anti-mite and delaying senility function, which is characterized in that the composition packet Ingredient containing following parts by weight: 7~9 parts of phellodendron extract, 23~28 parts of mung bean flour, 7~12 parts of grape seed extract, deep-sea mud 43~48 parts.
3. as claimed in claim 2 with the composition of anti-mite and delaying senility function, which is characterized in that the composition packet Ingredient containing following parts by weight: 8 parts of phellodendron extract, 25 parts of mung bean flour, 10 parts of grape seed extract, 45 parts of deep-sea mud.
4. the composition as claimed in any one of claims 1 to 3 with anti-mite and delaying senility function, which is characterized in that institute State the ingredient that composition includes following parts by weight: 5~10 parts of Radix et Caulis Opuntiae Dillenii extract, 3~4 parts of astaxanthin.
5. as claimed in claim 4 with the composition of anti-mite and delaying senility function, which is characterized in that the composition packet Ingredient containing following parts by weight: 8 parts of Radix et Caulis Opuntiae Dillenii extract, 3.5 parts of astaxanthin.
6. as claimed in claim 4 with anti-mite and delaying senility function composition, which is characterized in that the astaxanthin and The weight ratio of phellodendron extract are as follows: astaxanthin: phellodendron extract=7:16.
7. as claimed in claim 4 with the composition of anti-mite and delaying senility function, which is characterized in that in the composition It also include the hydroxyl fourth group-beta-cyclodextrin aqueous solution of 10~15 parts by weight, hydroxyl butyl-in the hydroxyl fourth group-beta-cyclodextrin aqueous solution The mass percent of beta-cyclodextrin is 10%.
8. a kind of skin care item comprising the described in any item compositions of claim 1~7.
9. skin care item as claimed in claim 8, which is characterized in that the skin care item are facial mask.
CN201710046291.1A 2017-01-22 2017-01-22 A kind of composition with anti-mite and delaying senility function and the skin care item comprising the composition Active CN106821844B (en)

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