CN104491884A - Gastrointestinal contrast agent containing traditional Chinese medicine ingredients - Google Patents
Gastrointestinal contrast agent containing traditional Chinese medicine ingredients Download PDFInfo
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- CN104491884A CN104491884A CN201410727097.6A CN201410727097A CN104491884A CN 104491884 A CN104491884 A CN 104491884A CN 201410727097 A CN201410727097 A CN 201410727097A CN 104491884 A CN104491884 A CN 104491884A
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- 239000003814 drug Substances 0.000 title claims abstract description 52
- 239000002872 contrast media Substances 0.000 title claims abstract description 28
- 230000002496 gastric effect Effects 0.000 title claims abstract description 24
- 239000004615 ingredient Substances 0.000 title claims abstract description 15
- 239000000284 extract Substances 0.000 claims abstract description 35
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 claims abstract description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 11
- 229930195725 Mannitol Natural products 0.000 claims abstract description 11
- 239000000594 mannitol Substances 0.000 claims abstract description 11
- 235000010355 mannitol Nutrition 0.000 claims abstract description 11
- 239000000706 filtrate Substances 0.000 claims description 22
- 238000002360 preparation method Methods 0.000 claims description 13
- 241000756943 Codonopsis Species 0.000 claims description 12
- 241000190633 Cordyceps Species 0.000 claims description 12
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 12
- 239000010135 fructus aurantii immaturus Substances 0.000 claims description 12
- 210000000582 semen Anatomy 0.000 claims description 12
- 239000012467 final product Substances 0.000 claims description 7
- 241000209140 Triticum Species 0.000 claims description 2
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- 238000000034 method Methods 0.000 abstract description 7
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- 230000009286 beneficial effect Effects 0.000 abstract description 2
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- 241000511998 Ceropegia Species 0.000 abstract 1
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- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 abstract 1
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- 235000002313 Crataegus paludosa Nutrition 0.000 abstract 1
- 235000009840 Crataegus x incaedua Nutrition 0.000 abstract 1
- 244000163122 Curcuma domestica Species 0.000 abstract 1
- 235000003392 Curcuma domestica Nutrition 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 240000004670 Glycyrrhiza echinata Species 0.000 abstract 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 abstract 1
- 241001556624 Gonostegia Species 0.000 abstract 1
- 241001673966 Magnolia officinalis Species 0.000 abstract 1
- 240000001307 Myosotis scorpioides Species 0.000 abstract 1
- 206010028813 Nausea Diseases 0.000 abstract 1
- 240000002948 Ophiopogon intermedius Species 0.000 abstract 1
- 244000248825 Peltandra virginica Species 0.000 abstract 1
- 235000001188 Peltandra virginica Nutrition 0.000 abstract 1
- 241000972673 Phellodendron amurense Species 0.000 abstract 1
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- 238000001035 drying Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
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- 229910052788 barium Inorganic materials 0.000 description 11
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 11
- 238000007689 inspection Methods 0.000 description 7
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 5
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a gastrointestinal contrast agent containing traditional Chinese medicine ingredients. The gastrointestinal contrast agent consists of the following components in parts by weight: 55-75 parts of barium sulfate, 5-15 parts of a traditional Chinese medicine extract and 20 parts of mannitol, wherein the traditional Chinese medicine extract is prepared by a method comprising the following steps: mixing the following materials in parts by weight: 20-30 parts of bark of Chinese corktree, 10-20 parts of dried tangerine peel, 10-20 parts of coix seed, 5-10 parts of all-grass of hirsute gonostegia, 10-20 parts of tuckahoe, 20-30 parts of hawthorn, 5-15 parts of herb of christensen ceropegia, 20-30 parts of officinal magnolia bark, 10-20 parts of immature bitter orange, 20-30 parts of dwarf lilyturf tuber, 10-20 parts of Chinese angelica, 10-20 parts of turmeric root-tuber, 5-15 parts of Chinese caterpillar fungus and 10-20 parts of licorice; mixing; immerging by adding water; decocting; filtering; and drying. The gastrointestinal contrast agent disclosed by the invention can achieve beneficial effects of shortening the examination time, relieving side effects (nausea, emesis, inappetence and fatigue) caused by X-ray examination and the like, can also achieve an effect of nourishing or taking good care of stomach, liver and the like, and has a better using effect.
Description
Technical field
The present invention relates to a kind of for radiology department, containing the gastrointestinal contrast agent of Chinese medicine ingredients.
Background technology
Barium meal and digestive tract barium meal, refer to and use barium sulfate as contrast agent, show a kind of inspection method of digestive tract with or without pathological changes under roentgen radiation x.When x-ray checks, because the density of the various organ of human body, tissue is different with thickness, so demonstrate the natural layer contrast of black and white.But at some position of human body, especially abdominal part, because the density broadly similar of inner good several organ, tissue, must import harmless contrast agent (as medicinal barium sulfate), improve display comparison degree artificially, just can reach desirable Checking on effect.This inspection method is called x-ray contrast examination clinically.When doing barium examination, barium agent will be eaten into by the people first checked, accepts gastrointestinal tract X-ray examination simultaneously.Gastrointestinal contrast agent of the prior art (barium meal) function singleness, to body without taking good care of, health-care effect.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of gastrointestinal contrast agent containing Chinese medicine ingredients, its side effect is low, takes good care of, health-care effect to body, and can strengthen gastrointestinal tract tensile force, promotes to wriggle, makes barium agent quickly by small intestinal, shorten the review time.
The present invention is achieved by the following technical solutions:
Containing a gastrointestinal contrast agent for Chinese medicine ingredients, be made up of the component of following weight portion: 55 ~ 75 parts, barium sulfate, Chinese medicine extract 5 ~ 15 parts, 20 parts, mannitol;
Wherein, Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 20 ~ 30 parts, Pericarpium Citri Reticulatae 10 ~ 20 parts, Semen Coicis 10 ~ 20 parts, Herba Gonostegiae hirtae 5 ~ 10 parts, 10 ~ 20 parts, Poria, Fructus Crataegi 20 ~ 30 parts, Herba Ceropegiae Christensenianae 5 ~ 15 parts, Cortex Magnoliae Officinalis 20 ~ 30 parts, Fructus Aurantii Immaturus 10 ~ 20 parts, Radix Ophiopogonis 20 ~ 30 parts, Radix Codonopsis 10 ~ 20 parts, Radix Curcumae 10 ~ 20 parts, Cordyceps 5 ~ 15 parts and 10 ~ 20 parts, Radix Glycyrrhizae, mixing, add water to submerge, decoct 60 ~ 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract; Described number is weight portion.
Preferably, described Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 25 parts, Pericarpium Citri Reticulatae 15 parts, Semen Coicis 15 parts, Herba Gonostegiae hirtae 8 parts, 15 parts, Poria, Fructus Crataegi 25 parts, Herba Ceropegiae Christensenianae 10 parts, Cortex Magnoliae Officinalis 25 parts, Fructus Aurantii Immaturus 15 parts, Radix Ophiopogonis 25 parts, Radix Codonopsis 15 parts, Radix Curcumae 15 parts, Cordyceps 10 parts and 15 parts, Radix Glycyrrhizae, mixing, add water to submerge, decoct 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
The preparation method of the described gastrointestinal contrast agent containing Chinese medicine ingredients is: get barium sulfate, Chinese medicine extract and mannitol, and mixing mixing, to obtain final product.
During use, temper, concentration is 50 ~ 80% (w/w), oral or clysis with barium, use amount 150g ~ 300g (calculating by contrast agent consumption).If patient is child, can take the circumstances into consideration to add some flavoring agents, as Icing Sugar, essence, citric acid etc.
Gastrointestinal contrast agent of the present invention, containing Chinese medicine extract, wherein, Cortex Phellodendri, Pericarpium Citri Reticulatae, Semen Coicis, Herba Gonostegiae hirtae compatibility can be alleviated, the Nausea and vomiting reaction that causes when reducing X-radiological survey X.The effect that Pericarpium Citri Reticulatae, Poria, Fructus Crataegi, Herba Ceropegiae Christensenianae compatibility can play stomach invigorating, help digestion, the effectively symptom such as inappetence, fatigue and weak after alleviation X-radiological survey X.Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus compatibility can strengthen gastrointestinal tract tensile force, promote to wriggle, and can shorten barium agent running time, (1 ~ 2 hour) can observe whole small intestinal in the short period of time when small bowel examination.Radix Ophiopogonis, Radix Codonopsis play the effect of nourishing the stomach, tonify deficiency.Radix Curcumae, Cordyceps compatibility play the effect of nourishing the liver hepatoprotective.Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.Mannitol can make barium agent quickly by small intestinal, can shorten the review time when carrying out small bowel enema.All medicine compatibilities, can play the effect alleviating the symptoms such as Nausea and vomiting, inappetence, fatigue and weak, also have the health-care effect such as stomach invigorating spleen invigorating, nourishing the liver hepatoprotective, also can be conducive to barium agent quickly through small intestinal, shorten the review time.
Gastrointestinal contrast agent containing Chinese medicine extract of the present invention, to clarify a diagnosis human body gastritis, gastric ulcer, gastric cancer, gastroptosis, prolapse of gastric mucosa, duodenal bulbar ulcer, gastrointestinal tumor etc., have no side effect, taking convenience, display, as clear, clinically to be taken through more than 80 examples, respond well, diagnosis is clear and definite, and can alleviate, alleviates or eliminate the symptom such as stomachache, gastric acid, Nausea and vomiting, inappetence, fatigue and weak of patient.
Gastrointestinal contrast agent of the present invention, side effect is low, except there is radiography function, can also play and shorten the review time, alleviate the beneficial effects such as the side effect (Nausea and vomiting, inappetence, fatigue and weak) that X-radiological survey X brings, also can play stomach, liver etc. and take good care of or health-care effect, result of use is better.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1 prepares the gastrointestinal contrast agent containing Chinese medicine ingredients
Get barium sulfate 130g, Chinese medicine extract 20g, mannitol 40g, mixing mixing, to obtain final product.
Described Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 25g, Pericarpium Citri Reticulatae 15g, Semen Coicis 15g, Herba Gonostegiae hirtae 8g, Poria 15g, Fructus Crataegi 25g, Herba Ceropegiae Christensenianae 10g, Cortex Magnoliae Officinalis 25g, Fructus Aurantii Immaturus 15g, Radix Ophiopogonis 25g, Radix Codonopsis 15g, Radix Curcumae 15g, Cordyceps 10g and Radix Glycyrrhizae 15g, mixing, add water to submerge, decoct 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
During use, temper, concentration 70% (w/w) is advisable, oral or clysis with barium, use amount 150g ~ 300g (calculating by contrast agent consumption).If patient is child, can take the circumstances into consideration to add some flavoring agents, as Icing Sugar, essence, citric acid etc.
Application example: 83 routine patients are checked, the gastrointestinal contrast agent of oral the present embodiment before checking.Result: after inspection, has 12 routine person under inspection's readmes to have the sensation of extremely slightly feeling sick, feeling sick, and after having 7 routine person under inspection's readme inspections, appetite is not very strong, has 71 routine person under inspection's readmes without nauseating, dizzy, vomiting, weak symptom, without sense of discomfort.
Embodiment 2 prepares the gastrointestinal contrast agent containing Chinese medicine ingredients
Get barium sulfate 110g, Chinese medicine extract 30g, mannitol 40g, mixing mixing, to obtain final product.
Described Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 20g, Pericarpium Citri Reticulatae 10g, Semen Coicis 20g, Herba Gonostegiae hirtae 10g, Poria 10g, Fructus Crataegi 20g, Herba Ceropegiae Christensenianae 15g, Cortex Magnoliae Officinalis 30g, Fructus Aurantii Immaturus 10g, Radix Ophiopogonis 20g, Radix Codonopsis 20g, Radix Curcumae 20g, Cordyceps 5g and Radix Glycyrrhizae 10g, mixing, add water to submerge, decoct 60min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
Using method is with embodiment 1.
Embodiment 3 prepares the gastrointestinal contrast agent containing Chinese medicine ingredients
Get barium sulfate 150g, Chinese medicine extract 10g, mannitol 40g, mixing mixing, to obtain final product.
Described Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 30g, Pericarpium Citri Reticulatae 20g, Semen Coicis 10g, Herba Gonostegiae hirtae 5g, Poria 20g, Fructus Crataegi 30g, Herba Ceropegiae Christensenianae 5g, Cortex Magnoliae Officinalis 20g, Fructus Aurantii Immaturus 20g, Radix Ophiopogonis 30g, Radix Codonopsis 10g, Radix Curcumae 10g, Cordyceps 15g and Radix Glycyrrhizae 20g, mixing, add water to submerge, decoct 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
Using method is with embodiment 1.
Embodiment 4 prepares the gastrointestinal contrast agent containing Chinese medicine ingredients
Get barium sulfate 110g, Chinese medicine extract 20g, mannitol 40g, mixing mixing, to obtain final product.
Described Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 22g, Pericarpium Citri Reticulatae 18g, Semen Coicis 12g, Herba Gonostegiae hirtae 8g, Poria 12g, Fructus Crataegi 28g, Herba Ceropegiae Christensenianae 8g, Cortex Magnoliae Officinalis 28g, Fructus Aurantii Immaturus 12g, Radix Ophiopogonis 28g, Radix Codonopsis 12g, Radix Curcumae 18g, Cordyceps 8g and Radix Glycyrrhizae 18g, mixing, add water to submerge, decoct 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
Using method is with embodiment 1.
Embodiment 5 prepares the gastrointestinal contrast agent containing Chinese medicine ingredients
Get barium sulfate 110g, Chinese medicine extract 30g, mannitol 40g, mixing mixing, to obtain final product.
Described Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 28g, Pericarpium Citri Reticulatae 13g, Semen Coicis 18g, Herba Gonostegiae hirtae 6g, Poria 18g, Fructus Crataegi 23g, Herba Ceropegiae Christensenianae 12g, Cortex Magnoliae Officinalis 23g, Fructus Aurantii Immaturus 18g, wheat east 23g, Radix Codonopsis 18g, Radix Curcumae 13g, Cordyceps 12g and Radix Glycyrrhizae 13g, mixing, add water to submerge, decoct 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
Using method is with embodiment 1.
Claims (5)
1., containing a gastrointestinal contrast agent for Chinese medicine ingredients, it is characterized in that: be made up of the component of following weight portion: 55 ~ 75 parts, barium sulfate, Chinese medicine extract 5 ~ 15 parts, 20 parts, mannitol;
Wherein, Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 20 ~ 30 parts, Pericarpium Citri Reticulatae 10 ~ 20 parts, Semen Coicis 10 ~ 20 parts, Herba Gonostegiae hirtae 5 ~ 10 parts, 10 ~ 20 parts, Poria, Fructus Crataegi 20 ~ 30 parts, Herba Ceropegiae Christensenianae 5 ~ 15 parts, Cortex Magnoliae Officinalis 20 ~ 30 parts, Fructus Aurantii Immaturus 10 ~ 20 parts, Radix Ophiopogonis 20 ~ 30 parts, Radix Codonopsis 10 ~ 20 parts, Radix Curcumae 10 ~ 20 parts, Cordyceps 5 ~ 15 parts and 10 ~ 20 parts, Radix Glycyrrhizae, mixing, add water to submerge, decoct 60 ~ 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
2. according to claim 1 containing Chinese medicine gastrointestinal contrast agent, it is characterized in that: described Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 25 parts, Pericarpium Citri Reticulatae 15 parts, Semen Coicis 15 parts, Herba Gonostegiae hirtae 8 parts, 15 parts, Poria, Fructus Crataegi 25 parts, Herba Ceropegiae Christensenianae 10 parts, Cortex Magnoliae Officinalis 25 parts, Fructus Aurantii Immaturus 15 parts, Radix Ophiopogonis 25 parts, Radix Codonopsis 15 parts, Radix Curcumae 15 parts, Cordyceps 10 parts and 15 parts, Radix Glycyrrhizae, mixing, add water to submerge, decoct 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
3. Chinese medicine gastrointestinal contrast agent according to claim 1, it is characterized in that: described Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 22g, Pericarpium Citri Reticulatae 18g, Semen Coicis 12g, Herba Gonostegiae hirtae 8g, Poria 12g, Fructus Crataegi 28g, Herba Ceropegiae Christensenianae 8g, Cortex Magnoliae Officinalis 28g, Fructus Aurantii Immaturus 12g, Radix Ophiopogonis 28g, Radix Codonopsis 12g, Radix Curcumae 18g, Cordyceps 8g and Radix Glycyrrhizae 18g, mixing, add water to submerge, decoct 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
4. gastrointestinal contrast agent according to claim 1, it is characterized in that: described Chinese medicine extract is obtained by following preparation method: get Cortex Phellodendri 28g, Pericarpium Citri Reticulatae 13g, Semen Coicis 18g, Herba Gonostegiae hirtae 6g, Poria 18g, Fructus Crataegi 23g, Herba Ceropegiae Christensenianae 12g, Cortex Magnoliae Officinalis 23g, Fructus Aurantii Immaturus 18g, wheat east winter 23g, Radix Codonopsis 18g, Radix Curcumae 13g, Cordyceps 12g and Radix Glycyrrhizae 13g, mixing, add water to submerge, decoct 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
5. the preparation method of the gastrointestinal contrast agent containing Chinese medicine ingredients described in Claims 1 to 4, is characterized in that: get barium sulfate, Chinese medicine extract and mannitol, and mixing mixing, to obtain final product.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105561126A (en) * | 2015-12-31 | 2016-05-11 | 孙伟 | Medicine for reducing effects of CT contrast agent, and preparation method thereof |
| CN109432448A (en) * | 2018-11-29 | 2019-03-08 | 天津凯茵科技有限公司 | A kind of gastrointestinal contrast agent for X-ray examination |
| CN110051774A (en) * | 2019-04-22 | 2019-07-26 | 重庆医科大学附属永川医院 | The reagent and preparation method thereof of contrast agent discharge in a kind of promotion human body |
| CN110314134A (en) * | 2019-01-24 | 2019-10-11 | 北京歌斐医疗器械有限公司 | A kind of gastrointestinal endoscopy auxiliary water and preparation method thereof |
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| CN102688506A (en) * | 2012-06-16 | 2012-09-26 | 山东省千佛山医院 | Gastrointestinal contrast agent containing Chinese herbal extracts |
| CN102698296A (en) * | 2012-06-28 | 2012-10-03 | 高玉纯 | Gastrointestinal series agent |
| CN103830750A (en) * | 2014-03-22 | 2014-06-04 | 济南伟传信息技术有限公司 | Gastrointestinal contrast agent containing Chinese herb extract |
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2014
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Patent Citations (3)
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| CN102688506A (en) * | 2012-06-16 | 2012-09-26 | 山东省千佛山医院 | Gastrointestinal contrast agent containing Chinese herbal extracts |
| CN102698296A (en) * | 2012-06-28 | 2012-10-03 | 高玉纯 | Gastrointestinal series agent |
| CN103830750A (en) * | 2014-03-22 | 2014-06-04 | 济南伟传信息技术有限公司 | Gastrointestinal contrast agent containing Chinese herb extract |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105561126A (en) * | 2015-12-31 | 2016-05-11 | 孙伟 | Medicine for reducing effects of CT contrast agent, and preparation method thereof |
| CN109432448A (en) * | 2018-11-29 | 2019-03-08 | 天津凯茵科技有限公司 | A kind of gastrointestinal contrast agent for X-ray examination |
| CN110314134A (en) * | 2019-01-24 | 2019-10-11 | 北京歌斐医疗器械有限公司 | A kind of gastrointestinal endoscopy auxiliary water and preparation method thereof |
| CN110051774A (en) * | 2019-04-22 | 2019-07-26 | 重庆医科大学附属永川医院 | The reagent and preparation method thereof of contrast agent discharge in a kind of promotion human body |
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| CN104491884B (en) | 2017-08-25 |
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