CN1730093A - Chinese traditional medicine preparation for treating cancer and application thereof - Google Patents
Chinese traditional medicine preparation for treating cancer and application thereof Download PDFInfo
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- CN1730093A CN1730093A CN 200510012708 CN200510012708A CN1730093A CN 1730093 A CN1730093 A CN 1730093A CN 200510012708 CN200510012708 CN 200510012708 CN 200510012708 A CN200510012708 A CN 200510012708A CN 1730093 A CN1730093 A CN 1730093A
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Abstract
The invention relates to a traditional Chinese medicinal composition for treating cancers, which is made into the forms of powder medicine or capsule containing the following medicinal herbs: common fennel fruit, dried ginger, Cinnamomum cassia, root of ballon flower, dahurian angelica root, bitter orange, licorice root, banksia rose, dried orange peel, magnolia bark, pinellia tuber, pilose asiabell root, Ligusticum wallichii, root of herbaceous peony, Chinese angelica root, Poria cocos, cyperus tuber and atractylodes rhizome. The invention also relates to the use of the preparation in preparing medicinal preparations for treating cancers.
Description
Technical field
The invention belongs to Chinese medicine preparation, the Chinese medicine preparation and the application thereof of particularly a kind of nourishing YIN and clearing away lung-heat, detoxicating and resolving stagnation of pathogens with therapeutic activity.Be applicable to treatment pulmonary carcinoma, other cancer is also had certain curative effect.
Background technology
The statistics of WHO (World Health Organization, World Health Organization (WHO)) shows that pulmonary carcinoma increases year by year with the mortality rate in every year 5～10%, and its sickness rate has risen to the 3rd of tumor total incidence.
Pulmonary carcinoma particularly in the male more sees, patients with lung cancer often have cough, chest pain, hemoptysis, out of breath, heating, weak, become thin and symptom such as anemia, can shift rapidly late period and cause death, bring great misery and financial burden to the patient, human beings'health and existence in serious threat.
Treatment to pulmonary carcinoma does not have comparatively ideal medicine and therapy as yet.Doctor trained in Western medicine can only be taked operation, radiotherapy, chemotherapy etc. at present, suppresses tumor development and prolongs patient's survival though these methods can reach to a certain extent, and these therapies all can bring many miseries and poison to pay effect to patient; All be difficult to accept for some old patient, particularly middle and advanced stage patient.
Motherland's medical science thinks that pulmonary carcinoma mainly is that mistake department falls in a surname because healthy energy is deficient, and imbalance of YIN and YANG causes the lungs functional disorder, disorder of QI movement, and blood is capable to be obstructed, and makes mental disorder stasis of blood poison glued, and it is long-pending with the passing of time to form the stasis of blood.
Summary of the invention
Purpose of the present invention is by the theory of Chinese medical science prescription, studies the Chinese medicine preparation of a kind of nourishing YIN and clearing away lung-heat, detoxicating and resolving stagnation of pathogens; And be applied in pulmonary carcinoma and other treatment for cancer.
Technical scheme of the present invention is:
Study a kind of Chinese medicine preparation for the treatment of cancer, it is characterized in that making powder or capsule by the medical material of following weight ratio:
Each 4～8 parts of Fructus Foeniculi, Rhizoma Zingiberiss; Respectively 7～11 parts of Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, Fructus Aurantiis; 9～13 parts in Radix Glycyrrhizae; 10～14 parts of the Radix Aucklandiae; Respectively 13～17 parts of Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, the Radix Paeoniae Albas; Respectively 30～34 parts of Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, Rhizoma Atractylodis.
Above-mentioned a kind of Chinese medicine preparation for the treatment of cancer is characterized in that also can making powder or capsule by the medical material of following weight ratio:
Each 5～7 parts of Fructus Foeniculi, Rhizoma Zingiberiss; Respectively 8～10 parts of Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, Fructus Aurantiis; 10～12 parts in Radix Glycyrrhizae; 11～13 parts of the Radix Aucklandiae; Respectively 14～16 parts of Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, the Radix Paeoniae Albas; Respectively 31～33 parts of Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, Rhizoma Atractylodis.
Above-mentioned a kind of Chinese medicine preparation for the treatment of cancer is characterized in that and can also make powder or capsule by the medical material of following weight ratio: each 6 parts of Fructus Foeniculi, Rhizoma Zingiberiss; Respectively 9 parts of Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, Fructus Aurantiis; 11 parts in Radix Glycyrrhizae; 12 parts of the Radix Aucklandiae; Respectively 15 parts of Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, the Radix Paeoniae Albas; Respectively 32 parts of Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, Rhizoma Atractylodis.
Above-mentioned a kind of method for making for the treatment of the Chinese medicine preparation of cancer is characterized in that:
Cortex Cinnamomi and Fructus Aurantii two flavors are crushed to separately by 100 mesh sieve fine powders; All the other 16 flavors are fried by the Chinese medicine processing method, are crushed to by 100 mesh sieve fine powders again; Mixing is packaged into powder or capsule.
Above-mentioned a kind of application for the treatment of the Chinese medicine preparation of cancer is characterized in that the application in preparation treatment lung-cancer medicament preparation.
Advantage of the present invention:
The present invention is a kind of Chinese medicine preparation, has no side effect, and medication is convenient, curative effect is obvious, onset is rapid and lasting, can obviously alleviate patient's misery, raising life quality, prolongation patient life.
The specific embodiment
A kind of Chinese medicine preparation for the treatment of cancer of embodiment one preparation
Fructus Foeniculi, each 6g of Rhizoma Zingiberis; Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, each 9g of Fructus Aurantii; Radix Glycyrrhizae 11g; Radix Aucklandiae 12g; Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, each 15g of the Radix Paeoniae Alba; Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, each 32g of Rhizoma Atractylodis.
Cortex Cinnamomi and Fructus Aurantii two flavors are crushed to separately by 100 mesh sieve fine powders; All the other 16 flavors are fried by the Chinese medicine processing method, are crushed to by 100 mesh sieve fine powders again; Mixing is packaged into powder or capsule.
Above-mentioned a kind of application for the treatment of the Chinese medicine preparation of cancer mainly is the application in preparation treatment lung-cancer medicament preparation; Other cancers also there is certain curative effect.
Clinical data
The case of case---selection all is once CT or X film making inspection, is diagnosed as pulmonary carcinoma person.Wherein, central type carcinoma of lung (betiding main bronchus, leaf bronchus or segmental bronchus person) is maximum, belongs to peripheral type carcinoma of lung (for the independent tuberosity in the pulmonary parenchyma) individually, and special type pulmonary carcinoma (pneumonia type pulmonary carcinoma, pancoast tumor and stability pulmonary carcinoma etc.) is accidental.All be clinic case, set up special-purpose case history respectively, followed up a case by regular visits to behind the clinical cure 3～6 months.Reject individual outage treatment whereabouts unknown person, write down more complete person's 50 examples, male's 39 examples, women 11 examples; Age is person's 2 examples more than 80 years old, 65～80 years old 17 example, 40～65 years old 29 example, 2 examples below 40 years old; Male's sickness rate is apparently higher than the women.Worker or retired employees' 40 examples, peasant's 10 examples.
The course of disease finds that elder is 9 months, finds that the shortest person is 2 months.
The main suit: often choke and cough, mostly be the paroxysmal irritative cough, sputum mixed with blood, chest and back pain, uncomfortable in chest out of breath, dry mouth and throat, constipation with dry stool, yellowish or reddish urine, poor appetite, dysphoria with feverish sensation in the chest palms and soles, night sweat.
Inspection: puffiness of face is simple and unadorned, emaciated physique, and malaise, the bluish complexion of breathing hard, purple lip with heating, has ecchymosis, thready and rapid pulse or deep,thready and rapid pulse more on the tongue.
Wherein, major part be in, patients with terminal, patient age is bigger than normal, physical weakness, the chemotherapy of can not or being unwilling to accept; Small part is a recurrence after operation, and female patient is a transferrer after breast carcinoma or the uterus carcinoma excision.
Therapeutic scheme---the prescription that uses is weight portion: each 4～8 parts of Fructus Foeniculi, Rhizoma Zingiberiss; Respectively 7～11 parts of Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, Fructus Aurantiis; 9～13 parts in Radix Glycyrrhizae; 10～14 parts of the Radix Aucklandiae; Respectively 13～17 parts of Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, the Radix Paeoniae Albas; Respectively 30～34 parts of Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, Rhizoma Atractylodis.In the treatment, every " part " is decided to be " 1g ".
Concocting method: Cortex Cinnamomi and Fructus Aurantii two flavors are crushed to separately by 100 mesh sieve fine powders; All the other 16 flavors are fried by the Chinese medicine processing method, are crushed to by 100 mesh sieve fine powders again; Mixing is packaged into powder or capsule.
Use dosage form to be powder or capsule, each 1 time sooner or later, each 5g boiled water takes, and avoids living, cold, peppery in the treatment.One month is a course of treatment, general three the course of treatment produce effects; Patient or the family members person of being ready can continue to take.
It is empty that pulmonary carcinoma is that whole body belongs to, local true disease, void be disease this, is the mark of disease in fact.By traditional Chinese medical science classification, YIN-deficiency type, deficiency of yang type or type of deficiency of both QI and YIN are arranged roughly.This side's the property of medicine is the tonifying the lung improving inspiration by invigorating the kidney, supplementing QI and nourishing YIN lung moistening, the heat clearing away collateral dredging that eliminates the phlegm, regulating QI and promoting blood circulation to remove blood stasis, softening the hard mass dispersing tumor eliminating stagnation.
Efficacy evaluation---with reference to " pulmonary carcinoma efficacy assessment standard ", the evaluation of therapeutic effect is divided into three grades:
Produce effects---part is alleviated, and symptom disappears substantially, checks that through CT or X film making the carninomatosis kitchen range dwindles more than 50%, and other objective determination takes an evident turn for the better; Do not see the state of an illness person of increasing the weight of more than half a year.
Effectively---the slight alleviation, symptom is improved substantially, checks that through CT or X film making the carninomatosis kitchen range dwindles, but the degree of dwindling is not as good as 50%, and other objective determination makes moderate progress; Do not see the state of an illness person of increasing the weight of more than three months.
Invalid---do not have to alleviate, check through CT or X film making, focus do not have dwindle or even increase to some extent, other objective determination does not have and improves or degenerate.
Annotate: other objective determination comprises: liver function, and renal function, blood, large and small just conventional is not all found special variation.
Curative effect is investigated the result
1. doing well,improving
The paroxysmal irritative cough reduces or 31 examples that disappear, improvement rate 62%; Sputum mixed with blood reduces or 35 examples that disappear, improvement rate 70%; Chest and back pain reduces or 41 examples that disappear, improvement rate 82%; The minimizing out of breath uncomfortable in chest or 45 examples that disappear, improvement rate 90%; Constipation with dry stool, yellowish or reddish urine 32 examples that take a turn for the better, improvement rate 64%; Appetite, sleep improvement 47 examples, improvement rate 94%.
2.CT or the X film making is checked
The carninomatosis kitchen range dwindles 50% above person's 25 examples, improvement rate 50%; The carninomatosis kitchen range dwindles 40～50% 8 examples, and improvement rate 16%; The carninomatosis kitchen range dwindles 20～40% 6 examples, and improvement rate 12%; The carninomatosis kitchen range does not have significant change person's 9 examples; Focus is increase person's 2 examples to some extent, deterioration rate only 4%.
3. quality of life improves
The quality of life remarkable improvement, come the treatment of my unit before, the life person that fully not can take care of oneself is 4 examples, is 8%, the person of can't take care of oneself at all is 46 examples, is 92%; After this Drug therapy, the life person that fully not can take care of oneself is 39 examples, is 78%, and the person of can't take care of oneself at all is 11 examples, is 22%.
4. life cycle
The medium and advanced lung cancer patient, even also often recurrence or shift of operation, and most of patient can not accept radiation and chemotherapy, so patient's life cycle is shorter, current phase patient's treatment has become a difficult problem to this.The life cycle of medium and advanced lung cancer, according to the interrelated data statistics, the survival rate in 1 year was on average less than 15% than short.Take this Drug therapy and follow up a case by regular visits to after 1 year, relate to bit rate 90%, have 41 in 45 patients with lung cancer relating to and still be still living and in good health, an annual survival rate of pulmonary carcinoma is unexpectedly up to 91.11%.
5. comprehensive therapeutic effect evaluation (is foundation with CT or X film making check result)
The clinical inefficiency obvious effective rate+effective percentage of the clinical obvious effective rate clinical effective rate of total routine number
50 examples, 100% 25 examples, 50% 14 examples, 28% 2 examples, 4% 39 examples 78%
Annotate: other has 9 examples, though CT or X film making check that the carninomatosis kitchen range has obviously and do not dwindle, feel, clinical symptoms and quality of life have clear improvement.
Model case
1. Zhang, man, 82 years old, the cough spitting of blood appearred in the peasant of Zibo City, patient at the beginning of 2004 4 months, symptoms such as the heat that occurs together headache, through film making of the X of city hospital line and CT examination, be diagnosed as lower-left pulmonary carcinoma companion obliterative inflammation, the patient is reluctant to accept chemotherapy, then accept treatment by Chinese herbs, medication after 15 days subjective symptoms be clearly better, X line film making and CT examination, the carninomatosis kitchen range dwindles 40%, continue to treat to June 25, drug withdrawal is gone home.Follow up a case by regular visits to after 3 months, X line film making and CT examination are done in suggestion again, and the carninomatosis kitchen range further dwindles 50%, with take traditional Chinese medicine before compare, lower-left agglomerate shadow disappears substantially, clinical cure is still living and in good health so far.
Liu so-and-so, the man, 64 years old, certain retired employees of unit, patient cough, chest pain are surplus February, through inspections such as X line film makings, are diagnosed as bottom right pulmonary carcinoma, in October, 2004, begin to change taking traditional Chinese medicine upon somebody's introduction.Again through CT examination, the bottom right lung has 40 * 50mm shade before taking traditional Chinese medicine, and in conjunction with clinical other symptoms, diagnosis is with preceding identical.Through taking this Chinese medicine preparation 3 months, right lung X sheet shade is contracted to 20 * 20mm, and patient's subjective symptoms is obviously improved.After treatment is 1 month again, and right lung X sheet shade disappears drug withdrawal substantially.Follow up a case by regular visits to after 6 months, take care of oneself, can also participate in community's socially useful activity.
Lee so-and-so, woman, 57 years old, the retired worker, first visit in October, 2004, cough ant phlegm, low grade fever (37.6～38.2 ℃) two months, the thick Huang of expectorant has a little blood streak, and spontaneous perspiration is often arranged, lassitude and weak, weight loss, the rhythm of the heart is normal, the dried moist rale of right lung portion audible, the right lung respiratory harshness, blood pressure 16/9.22Pa, private prosecution in JIUYUE, 2002 row breast carcinoma excision.In June, 2004, higher level's examination in hospital was found cancer cell metastasis to right upper lung, and (20 * 30mm), the mood crisis appears to CT examination right upper lung shade in patient, and life is lost the confidence.After take Chinese medicine preparation of the present invention, adhered to taking medicine four months, through province Affiliated Hospital CT examination, tumor is reduced to 5 * 10mm, continues to take medicine 2 months, the CT examination tumor cloud disappears.Because this medicine can improve patient's autoimmunity, patient has not only treated pulmonary carcinoma after taking this medicine, and other complication, complication are also effective in cure.
Followed up a case by regular visits in 3 months after the drug withdrawal, do not see that cancer continues to shift, can participate in community's recreational and sports activities, the patient has recovered life confidence; The mental status is good, 1.5 kilograms of weight increase.
A kind of Chinese medicine preparation for the treatment of cancer of embodiment 2 preparations
Preparation is made up of the medical material of following weight ratio:
Fructus Foeniculi, each 8g of Rhizoma Zingiberis; Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, each 11g of Fructus Aurantii; Radix Glycyrrhizae 13g; Radix Aucklandiae 14g; Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, each 17g of the Radix Paeoniae Alba; Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, each 34g of Rhizoma Atractylodis.All the other are with embodiment 1.
A kind of Chinese medicine preparation for the treatment of cancer of embodiment 3 preparations
Preparation is made up of the medical material of following weight ratio:
Fructus Foeniculi, each 4g of Rhizoma Zingiberis; Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, each 7g of Fructus Aurantii; Radix Glycyrrhizae 9g; Radix Aucklandiae 10g; Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, each 13g of the Radix Paeoniae Alba; Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, each 30g of Rhizoma Atractylodis.All the other are with embodiment 1.
A kind of Chinese medicine preparation for the treatment of cancer of embodiment 4 preparations
Preparation is made up of the medical material of following weight ratio:
Fructus Foeniculi, each 7g of Rhizoma Zingiberis; Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, each 10g of Fructus Aurantii; Radix Glycyrrhizae 12g; Radix Aucklandiae 13g; Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, each 16g of the Radix Paeoniae Alba; Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, each 33g of Rhizoma Atractylodis.All the other are with embodiment 1.
A kind of Chinese medicine preparation for the treatment of cancer of embodiment 5 preparations
Preparation is made up of the medical material of following weight ratio:
Fructus Foeniculi, each 5g of Rhizoma Zingiberis; Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, each 8g of Fructus Aurantii; Radix Glycyrrhizae 10g; Radix Aucklandiae 11g; Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, each 14g of the Radix Paeoniae Alba; Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, each 31g of Rhizoma Atractylodis.All the other are with embodiment 1.
Claims (5)
1. Chinese medicine preparation for the treatment of cancer is characterized in that making powder or capsule by the medical material of following weight ratio:
Each 4～8 parts of Fructus Foeniculi, Rhizoma Zingiberiss; Respectively 7～11 parts of Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, Fructus Aurantiis; 9～13 parts in Radix Glycyrrhizae; 10～14 parts of the Radix Aucklandiae; Respectively 13～17 parts of Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, the Radix Paeoniae Albas; Respectively 30～34 parts of Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, Rhizoma Atractylodis.
2. according to the described a kind of Chinese medicine preparation for the treatment of cancer of claim 1, it is characterized in that making powder or capsule by the medical material of following weight ratio:
Each 5～7 parts of Fructus Foeniculi, Rhizoma Zingiberiss; Respectively 8～10 parts of Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, Fructus Aurantiis; 10～12 parts in Radix Glycyrrhizae; 11～13 parts of the Radix Aucklandiae; Respectively 14～16 parts of Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, the Radix Paeoniae Albas; Respectively 31～33 parts of Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, Rhizoma Atractylodis.
3. according to the described a kind of Chinese medicine preparation for the treatment of cancer of claim 1, it is characterized in that making powder or capsule: each 6 parts of Fructus Foeniculi, Rhizoma Zingiberiss by the medical material of following weight ratio; Respectively 9 parts of Cortex Cinnamomi, Radix Platycodonis, the Radix Angelicae Dahuricae, Fructus Aurantiis; 11 parts in Radix Glycyrrhizae; 12 parts of the Radix Aucklandiae; Respectively 15 parts of Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Chuanxiong, the Radix Paeoniae Albas; Respectively 32 parts of Radix Angelicae Sinensis, Poria, Rhizoma Cyperi, Rhizoma Atractylodis.
4. according to claim 1,2 or 3 described a kind of method for makings for the treatment of the Chinese medicine preparation of cancer, it is characterized in that:
Cortex Cinnamomi and Fructus Aurantii two flavors are crushed to separately by 100 mesh sieve fine powders; All the other 16 flavors are fried by the Chinese medicine processing method, are crushed to by 100 mesh sieve fine powders again; Mixing is packaged into powder or capsule.
5. according to claim 1,2 or 3 described a kind of application for the treatment of the Chinese medicine preparation of cancer, it is characterized in that the application in preparation treatment lung-cancer medicament preparation.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101543613B (en) * | 2009-05-06 | 2012-07-04 | 古德祥 | Cancerocidal pill and preparation method thereof |
| CN103212022A (en) * | 2013-04-02 | 2013-07-24 | 成都科创佳思科技有限公司 | Chinese patent medicament for treating scars |
| CN105267509A (en) * | 2015-11-19 | 2016-01-27 | 吴斌 | Drug for treating breast cancer |
| CN105311289A (en) * | 2015-12-01 | 2016-02-10 | 青岛市肿瘤医院 | Formula of traditional Chinese medicine for treating lung cancer due to accumulation of phlegm dampness in lung |
-
2005
- 2005-08-01 CN CN 200510012708 patent/CN1730093A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101543613B (en) * | 2009-05-06 | 2012-07-04 | 古德祥 | Cancerocidal pill and preparation method thereof |
| CN103212022A (en) * | 2013-04-02 | 2013-07-24 | 成都科创佳思科技有限公司 | Chinese patent medicament for treating scars |
| CN105267509A (en) * | 2015-11-19 | 2016-01-27 | 吴斌 | Drug for treating breast cancer |
| CN105311289A (en) * | 2015-12-01 | 2016-02-10 | 青岛市肿瘤医院 | Formula of traditional Chinese medicine for treating lung cancer due to accumulation of phlegm dampness in lung |
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