CN103495022A - Traditional Chinese medicine for adjuvant therapy of aids - Google Patents
Traditional Chinese medicine for adjuvant therapy of aids Download PDFInfo
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- CN103495022A CN103495022A CN201310494211.0A CN201310494211A CN103495022A CN 103495022 A CN103495022 A CN 103495022A CN 201310494211 A CN201310494211 A CN 201310494211A CN 103495022 A CN103495022 A CN 103495022A
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Abstract
The invention discloses traditional Chinese medicine for adjuvant therapy of aids. The traditional Chinese medicine for the adjuvant therapy of the aids comprises the following raw material components of 3 to 8 parts of ginseng, 10 to 15 parts of radix ophiopogonis, 4 to 10 parts of schisandra chinensis, 10 to 20 parts of Chinese yam, 10 to 15 parts of medlar, 6 to 12 parts of cortex moutan, 10 to 20 parts of poria cocos and 6 to15 parts of wintercreeper. The traditional Chinese medicine for the adjuvant therapy of the aids has the functions of replenishing the vital essence and removing heat and invigorating the spleen and supplementing qi, and is mainly used for treating lassitude of spirit, lack of strength, dizziness, dry mouths, vexing heat in thechest, palms andsoles, astriction, red tongue and littlefur, fine and string-like pulse and other symptoms. The traditional Chinese medicine for the adjuvant therapy of the aids can enhance the immunity of aids patients, and increase CD4 values. The traditional Chinese medicine for the adjuvant therapy of the aids can relief the symptoms of diarrhea, inappetence, the astriction, feeling of listlessness and inertness, insomnia and the like of the patients, enhance the immunity of the patients, support the healthy energy, and improve the cure rate.
Description
Technical field
The present invention discloses a kind of Chinese medicine for auxiliary treatment AIDS, and relates to the production method of this medicine.
Background technology
Acquired immune deficiency syndrome (AIDS), i.e. acquired immune deficiency syndrome (AIDS), English name Acquired Immune Deficiency Syndrome, AIDS.The mankind because cause immunodeficiency after infecting HIV (human immunodeficiency virus) (Human Immunodeficiency Virus, HIV), concurrent a series of opportunistic infection and tumor, severe patient can cause dead syndrome.At present, acquired immune deficiency syndrome (AIDS) has become the public health problem of serious threat people of the world health.Nineteen eighty-three, the mankind find HIV first.At present, acquired immune deficiency syndrome (AIDS) becomes a kind of controlled chronic disease from a kind of fatal disease.HAART full name highly active antiretroviral therapy, HAART, be commonly called as HAART.Being to be proposed in 1996 by scientist Chinese descendant in America He great Yi, is to combine and make for treating the method for acquired immune deficiency syndrome (AIDS) by the antiviral drugs more than three kinds or three kinds, is the most basic Therapeutic Method of acquired immune deficiency syndrome (AIDS).Although combine and make can kill HIV (human immunodeficiency virus) for treating acquired immune deficiency syndrome (AIDS) by the antiviral drugs more than three kinds or three kinds, suppress to greatest extent copying of virus, the Save and restore immunologic function, reduce case fatality rate and the diseases related sickness rate of HIV, but side effect simultaneously is also very important, as: cause gastrointestinal upset, anorexia, vomiting, diarrhoea, the particularly bad crowd of gastrointestinal function, the untoward reaction phenomenon of this respect is more obvious.And gastrointestinal upset will reduce the absorption of human body nutrient substance, greatly reduce to support antiviral ability, particularly diarrhoea, can make patient body weaker, and immunity is low, finally can cause a series of immunity syndrome of falling.The Chinese herbal medicine side effect is little, can long-term taking, and can strengthening the body resistance, strengthen patient's body constitution.Chinese herbal medicine and antiviral drugs therapeutic alliance acquired immune deficiency syndrome (AIDS), can improve patient's cure rate.The patent of invention that Chinese Patent Application No. is CN201110426516.9 discloses a kind of Chinese medicine preparation of auxiliary treatment AIDS, and this Chinese medicine preparation is to be made by the raw material of Chinese medicine of following parts by weight: Radix Astragali 15-30 part, Rhizoma Atractylodis Macrocephalae 3-8 part, Poria 6-15 part, Fructus Lycii 6-15 part, Placenta Hominis 2-6 part, Gecko 15-30 part, Ganoderma 3-8 part, Radix Paeoniae Alba 2-6 part, Radix Salviae Miltiorrhizae 2-6 part, Radix Aconiti Lateralis Preparata 3-8 part, Radix Polygalae fallacis 3-8 part.That this Chinese medicine preparation and antiviral combination improve is weak, indigestion and loss of appetite, breathe hard and the effect of lumbago is better than applying merely antiviral agents.Chinese medicine preparation of the open auxiliary treatment AIDS of the patent of invention that Chinese Patent Application No. is CN201010148762.8 and preparation method thereof.This Chinese medicine preparation is made by the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, licorice raw material, can make and be easy to the Chinese medicine preparation of taking, carrying, for the preparation of the medicine for the treatment of acquired immune deficiency syndrome (AIDS).At five routine clinical effectivenesses of medical institutions 120, show, this Chinese medicine preparation can obviously improve the AIDS patients symptom, improves living quality of AIDS patients.
Summary of the invention
The objective of the invention is to disclose a kind of Chinese medicine of auxiliary treatment AIDS.This Chinese medicine and AIDS virus resisting therapeutic alliance HIV sufferers, the side effect that can alleviate Western medicine, strengthening the body resistance, improve patient's immunity, cd4 cell number.
Technical scheme of the present invention is:
The Chinese medicine of auxiliary treatment AIDS, the raw material weight umber of its composition is as follows: Radix Ginseng 3～8; Radix Ophiopogonis 10～15; Fructus Schisandrae Chinensis 4～10; Rhizomadioscoreae 10～20; Fructus Lycii 10～15; Cortex Moutan 6～12; Poria 10～20; Caulis Seu Folium Euonymi Fortunei 6～15.
The dry root that described Radix Ginseng is Araliaceae Radix Ginseng Panax ginseng C. A. Mey.Radix Ginseng is flat, sweet in the mouth, micro-hardship, tepor.Return spleen, lung meridian, heart channel.Effect: strongly invigorating primordial QI, multiple arteries and veins is admittedly de-, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the Fructus Alpiniae Oxyphyllae of calming the nerves.Cure mainly: impairment caused by overstrain is deficient, lack of appetite, asthenia, regurgitation are told food, stool lingering diarrhea, empty cough with asthma are short, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency multiple, the disease of all qi-blood-body fluid deficiencies.
The dried root that be liliaceous plant Radix Ophiopogonis (dwarf lilyturf) Ophiopogon japonicus (T.f) Ker-Gawl. described Radix Ophiopogonis.Radix Ophiopogonis, sweet in the mouth, micro-hardship, be slightly cold.GUIXIN, lung, stomach warp.Function with cure mainly: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, the sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
Described Fructus Schisandrae Chinensis is Magnoliaceae Fructus Schisandrae Chinensis Schisandra chinensls(Turcz) dry fruit of Baill..Ancient medical book claim Fructus Schisandrae Chinensis Wei Chi Zhu, profound and, can and, list in the earliest Sheng Nong's herbal classic top grade, herbal function is the power of strengthening by means of tonics, medical value is high." Bencao Jingshu " upper record: Fructus Schisandrae Chinensis master QI invigorating person, all gas of lung master, acid can be received, and is just entering the lung tonifying the lung, therefore QI invigorating is also.Its main cough with dyspnea person, the deficiency of vital energy is above stopped up and is not returned unit, and sour flavor having the property of astringing, take the photograph gas and return unit, and cough with dyspnea is from removing.Impairment caused by overstrain is won thin, tonifying for the deficiency, reinforcing YIN-essence, beneficial man's essence.
The rhizome that described Rhizomadioscoreae is monocotyledon Dioscoreaceae Dioscoreaceae Rhizoma Dioscoreae Dioscorea oppositaThunb., have the effect of spleen reinforcing nourishing the stomach, invigorating the lung and the kidney.Can be used for treating insufficiency of the spleen chronic diarrhea, chronic enteritis, cough and asthma due to lung deficiency, chronic gastritis, diabetes, seminal emission, the enuresis, be with inferior disease.
The dry mature fruit that described Fructus Lycii is plant of Solanaceae lycium barbarum Lycium barbarum L..Its sweet in the mouth, the flat effect with the liver and the kidney tonifying of property, say in Compendium of Material Medica and " take for a long time hard muscles and bones, make light of one's life by commiting suicide not old, cold-resistant summer-heat." traditional Chinese medical science commonly used it treat hepatic and renal YIN deficiency, soreness of the waist and knees, dizziness, forgetful, dizzy, the many tear of blurred vision, quench one's thirst, the disease such as seminal emission.Modern pharmacology studies confirm that Fructus Lycii scalable body's immunity, can effectively suppress tumor growth and cell mutation, has slow down aging, the effect of anti-fatty liver, adjusting blood fat and the aspects such as blood glucose, energy, and is applied to clinical.The Fructus Lycii taking convenience, can be used as medicine, chew clothes, steep in wine.Fructus Lycii contains a large amount of polysaccharide, the effects such as existing existing a lot of research shows that lycium barbarum polysaccharide has Promote immunity, defying age, antitumor, removing free radical, resisting fatigue, radioprotective, protects the liver, reproductive function protection and improvement.
Described Cortex Moutan, also be Cortex Moutan, for being the dry root bark of ranunculaceae peony Paeonia suffruticosa Andr..Cortex Moutan is cold in nature, bitter in the mouth; Cool; Be slightly cold.GUIXIN; Liver; Kidney; Lung meridian. effect: clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; The rheumatism pyretic arthralgia.
Described Poria, be commonly called as Poria, Song Ling, Poria, and the dry sclerotia for On Polyporaceae Poria Poria cocos (Schw.) Wolf, colonize in the fungi plant on pinaster root, and shape is as Rhizoma Dioscoreae esculentae, crust pitchy, the inside white or pink.The dry sclerotia that its protozoa is the On Polyporaceae Poria, multiparasitization is in the root of Pinus massoniana Lamb or Pinus densiflora.Originate in the ground such as Yunnan, Anhui, Hubei, Henan, Sichuan.Ancients claim that Poria is " god medicine " at 4 o'clock, because its effect is very extensive, regardless of the four seasons, by it and various compatibility of drugs, no matter cold, temperature, wind, all diseases that wets can be brought into play its unique effects.Poria sweet in the mouth, light, property are flat, be used as medicine there is promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.
Dry stem, leaf that described Caulis Seu Folium Euonymi Fortunei is Celastraceae burning buss Caulis Seu Folium Euonymi Fortunei Euonymus fortunei (Turcz.) Hand.-Mazz..Caulis Seu Folium Euonymi Fortunei has relaxing muscles and tendons and activating QI and blood in the collateral, the effect of hemostasis repercussive, and the chronic diarrhea that acquired immune deficiency syndrome (AIDS) is caused has good curative effect.
The Chinese medicine of auxiliary treatment AIDS of the present invention, by the conventional formulation technique of relevant dosage form, adds appropriate amount of auxiliary materials to make corresponding dosage form, and said medicine can be made oral liquid, granule, capsule, tablet or other pharmaceutically useful dosage form.
The Chinese medicine oral liquid production method of above-mentioned auxiliary treatment AIDS is: get by weight ratio Radix Ginseng; Radix Ophiopogonis; Fructus Schisandrae Chinensis; Rhizomadioscoreae; Fructus Lycii; Cortex Moutan; Poria and Caulis Seu Folium Euonymi Fortunei, add water 8-10 by gross weight and doubly decoct secondary, and each 2 hours, collecting decoction, filtered, and adds adjuvant, makes oral liquid.
The Chinese medicinal capsule production method of above-mentioned auxiliary treatment AIDS is: get by weight ratio Radix Ginseng; Radix Ophiopogonis; Fructus Schisandrae Chinensis; Rhizomadioscoreae; Fructus Lycii; Cortex Moutan; Poria and Caulis Seu Folium Euonymi Fortunei, add water 8-10 by gross weight and doubly decoct secondary, and each 2 hours, collecting decoction, filter, be concentrated into the thick paste that relative density is 1.28～1.30, then dry, pulverize into fine powder below 80 ℃, add adjuvant, mix, granulation agent, capsule or tablet.
The Chinese medicine of auxiliary treatment AIDS of the present invention is " the Treating AIDS with Traditional Chinese Medicine clinical technology scheme (trying) " according to the tcm clinical practice characteristics of acquired immune deficiency syndrome (AIDS) and State Administration of Traditional Chinese Medicine's formulation, in conjunction with factors such as the climate characteristic in Guangxi, constitutive character, environmental factors, staff conditions, a kind of medicine that adapts to the most of infection populations in Guangxi of innovation and creation, have the effect that improves AIDS related complex shape sign.
The good effect that the present invention produces is: the Chinese medicine preparation of auxiliary treatment AIDS of the present invention has replenishing YIN and removing heat, the invigorating the spleen and benefiting QI effect, function cures mainly: for spiritlessness and weakness, have a dizzy spell, the symptom such as the few stringy and thready pulse of xerostomia, dysphoria with feverish sensation in the chest palms and soles, constipation, red tongue tongue, improve the symptoms such as patient's diarrhoea, inappetence, lethargy, insomnia with antiviral combination, strengthening the body resistance, increase patient's cd4 cell value, enhancing immunity, the cure rate of raising HIV sufferers.
The specific embodiment
Embodiment 1
Get by weight ratio 3 parts of Radix Ginsengs; 15 parts of Radix Ophiopogonis; 10 parts of Fructus Schisandrae Chinensis; 20 parts of Rhizomadioscoreae; 10 parts of Fructus Lyciis; 8 parts of Cortex Moutans; 16 parts, Poria; 12 parts of Caulis Seu Folium Euonymi Fortuneis, add water 8-10 by gross weight and doubly decoct secondary, and each 2 hours, collecting decoction, filtered, and adds adjuvant, makes oral liquid.
Embodiment 2
Get by weight ratio 5 parts of Radix Ginsengs; 12 parts of Radix Ophiopogonis; 7 parts of Fructus Schisandrae Chinensis; 15 parts of Rhizomadioscoreae; 15 parts of Fructus Lyciis; 6 parts of Cortex Moutans; 10 parts, Poria; 15 parts of Caulis Seu Folium Euonymi Fortuneis, add water 8-10 by gross weight and doubly decoct secondary, and each 2 hours, collecting decoction, filtered, and adds adjuvant, makes oral liquid.
Embodiment 3
Get by weight ratio 8 parts of Radix Ginsengs; 10 parts of Radix Ophiopogonis; 4 parts of Fructus Schisandrae Chinensis; 10 parts of Rhizomadioscoreae; 12 parts of Fructus Lyciis; 12 parts of Cortex Moutans; 20 parts, Poria; 6 parts of Caulis Seu Folium Euonymi Fortuneis, add water 8-10 by gross weight and doubly decoct secondary, and each 2 hours, collecting decoction, filtered, and is concentrated into the thick paste that relative density is 1.28～1.30, then, below 80 ℃, dry, pulverize into fine powder, adds adjuvant, mixes, and makes capsule.
Embodiment 4
Get by weight ratio 6 parts of Radix Ginsengs; 12 parts of Radix Ophiopogonis; 6 parts of Fructus Schisandrae Chinensis; 15 parts of Rhizomadioscoreae; 12 parts of Fructus Lyciis; 9 parts of Cortex Moutans; 12 parts, Poria; 10 parts of Caulis Seu Folium Euonymi Fortuneis, add water 8-10 by gross weight and doubly decoct secondary, and each 2 hours, collecting decoction, filtered, and is concentrated into the thick paste that relative density is 1.28～1.30, then, below 80 ℃, dry, pulverize into fine powder, adds adjuvant, mixes, and makes capsule.
Embodiment 5
Get by weight ratio 7 parts of Radix Ginsengs; 12 parts of Radix Ophiopogonis; 8 parts of Fructus Schisandrae Chinensis; 12 parts of Rhizomadioscoreae; 13 parts of Fructus Lyciis; 12 parts of Cortex Moutans; 18 parts, Poria; 12 parts of Caulis Seu Folium Euonymi Fortuneis, add water 8-10 by gross weight and doubly decoct secondary, and each 2 hours, collecting decoction, filtered, and is concentrated into the thick paste that relative density is 1.28～1.30, then, below 80 ℃, dry, pulverize into fine powder, adds adjuvant, mixes, and makes tablet.
Embodiment 6
Get by weight ratio 4 parts of Radix Ginsengs; 10 parts of Radix Ophiopogonis; 9 parts of Fructus Schisandrae Chinensis; 17 parts of Rhizomadioscoreae; 14 parts of Fructus Lyciis; 7 parts of Cortex Moutans; 15 parts, Poria; 11 parts of Caulis Seu Folium Euonymi Fortuneis, add water 8-10 by gross weight and doubly decoct secondary, and each 2 hours, collecting decoction, filtered, and is concentrated into the thick paste that relative density is 1.28～1.30, then, below 80 ℃, dry, pulverize into fine powder, adds adjuvant, mixes the granulation agent.
Clinical trial data
The drug provision of embodiments of the invention 1-6, to the Guangxi provincial hospital, carries out the therapeutic alliance acquired immune deficiency syndrome (AIDS) with acquired immune deficiency syndrome (AIDS) antiviral Western medicine, and 100 routine patients' treatment situation is as follows.
One, clinical observation:
1. preparation for treating acquired immune deficiency syndrome (AIDS) clinical symptoms of the present invention, sign situation of change (table 1):
Tcm clinical practice symptom, sign situation of change before and after this compound treatment of table 1
2. the CD4 situation of change (table 2) of preparation for treating acquired immune deficiency syndrome (AIDS) of the present invention:
CD4 situation of change (individual/μ l) before and after table 2 preparation for treating of the present invention
Two, model case:
Case 1:
AIDSinfected patient Zhu, the company clerk, the primary dcreening operation HIV positive when erythra occurring in 2006, make a definite diagnosis HIV by confirmatory test and infect.Surveyed at that time cd4 cell and be counted as 586, body weight is 62kg, starts to occur inappetence in June, 2011, dyspepsia, spirit is poor, becomes thin, weak, spontaneous perspiration, easy catching a cold, 8 times every year on average, diarrhoea, average every day 4 times, insomnia, sleep quality worse and worse, is easily waken up with a start, watery stool, the time fear of cold, acid regurgitation arranged, vomiting watery fluid, deep pulse is unable, pale tongue with white fur; Start to accept HAART at the beginning of 2012, fear of cold, acid regurgitation, vomiting watery fluid, deep pulse is unable, and the symptoms such as pale tongue with white fur slightly take a favorable turn, but spirit is still dispirited, easily wakes up with a start, the time diarrhoea is arranged, satisfy and carry out hospital admission, survey cd4 cell and be counted as 415, body weight is 53kg, the traditional Chinese medical science is examined as having loose bowels, and syndrome of yang deficiency of spleen and kidney is taken the medicine of the embodiment of the present invention 4, every day three times, each three, every about 1.8g, in May, 2013, survey cd4 cell and be counted as 543, body weight is 56kg, and appetite is normal, digests; Stool is normal, on average once a day; Energetic, sleep quality is good, has rosy cheeks.
Case 2
AIDSinfected patient Wang, the driver, primary dcreening operation HIV positive when Yin Gaore will be in hospital in the end of the year 2004, be diagnosed as HIV by Guangxi District CDC confirmatory test and infect.Survey at that time cd4 cell and be counted as 557, start to occur becoming thin in April, 2010, weak, spontaneous perspiration, easy catching a cold, on average per month 1 time, inappetence, dyspepsia, spirit is poor, the time fear of cold arranged, the time acid regurgitation arranged, vomiting watery fluid, deep-slow pulse is unable, pale tongue with white fur, often suffer from diarrhoea, every day 4～5 times, from taking Western medicine, have no improvement, then the Lai Woyuan center is medical, survey cd4 cell and be counted as 421, the traditional Chinese medical science is examined as syndrome of yang deficiency of spleen and kidney, give the medicine of this prescription embodiment of the present invention 2, every day three times, each 20ml, in June, 2013, survey cd4 cell and be counted as 476, appetite is normal, digest, stool is normal, on average once a day, energetic, sleep quality is good, have rosy cheeks.
clinical conclusion
Medicine of the present invention and antiviral combination application, clinical effectiveness shows, medicine of the present invention and antiviral Western medicine use in conjunction are after 12 months, except myalgia and dry mouth and tougue, other symptom and signs all improve significantly, wherein, inappetence, dyspepsia, weak, indigestion and loss of appetite, suffer from diarrhoea, breathe hard and the curative effect of lumbago is better than using merely antiviral agents, to the curative effect of other symptom and signs with simple by antiviral agents there are no significant difference.Illustrate that medicine of the present invention combines symptoms such as can improving patient's diarrhoea, inappetence, lethargy, insomnia with the antiviral Western medicine, strengthen patient's immunity, strengthening the body resistance, improve cure rate.
Claims (4)
1. the Chinese medicine of an auxiliary treatment AIDS, is characterized in that, its composition comprises the raw material of following parts by weight:
Radix Ginseng 3～8; Radix Ophiopogonis 10～15; Fructus Schisandrae Chinensis 4～10; Rhizomadioscoreae 10～20; Fructus Lycii 10～15; Cortex Moutan 6～12; Poria 10～20; Caulis Seu Folium Euonymi Fortunei 6～15.
2. as the Chinese medicine of the described auxiliary treatment AIDS of claim l, it is characterized in that, described medicine is oral liquid, granule, capsule, tablet or other pharmaceutically useful dosage form.
3. as the production method of the Chinese medicine of the described auxiliary treatment AIDS of claim l, it is characterized in that, get by weight ratio Radix Ginseng; Radix Ophiopogonis; Fructus Schisandrae Chinensis; Rhizomadioscoreae; Fructus Lycii; Cortex Moutan; Poria and Caulis Seu Folium Euonymi Fortunei, add water 8-10 by gross weight and doubly decoct secondary, and each 2 hours, collecting decoction, filtered, and adds adjuvant, makes oral liquid.
4. as the production method of the Chinese medicine of the described auxiliary treatment AIDS of claim l, it is characterized in that, get by weight ratio Radix Ginseng; Radix Ophiopogonis; Fructus Schisandrae Chinensis; Rhizomadioscoreae; Fructus Lycii; Cortex Moutan; Poria and Caulis Seu Folium Euonymi Fortunei, add water 8-10 by gross weight and doubly decoct secondary, and each 2 hours, collecting decoction, filter, be concentrated into the thick paste that relative density is 1.28～1.30, then dry, pulverize into fine powder below 80 ℃, add adjuvant, mix, granulation agent, capsule or tablet.
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| CN108926588A (en) * | 2018-08-22 | 2018-12-04 | 广西医科大学 | Winter creeper extract and preparation method thereof and AntiHIV1 RT activity application |
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| CN102824529A (en) * | 2011-06-17 | 2012-12-19 | 刘杏利 | Traditional Chinese medicine for nourishing yin and yang, tonifying qi and producing blood, and prolonging life |
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| CN102824529A (en) * | 2011-06-17 | 2012-12-19 | 刘杏利 | Traditional Chinese medicine for nourishing yin and yang, tonifying qi and producing blood, and prolonging life |
Non-Patent Citations (1)
| Title |
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| 肖艳芬等: "扶芳藤提取物对小鼠免疫功能的影响研究", 《现代医药卫生 》, vol. 28, no. 12, 30 June 2012 (2012-06-30) * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108926588A (en) * | 2018-08-22 | 2018-12-04 | 广西医科大学 | Winter creeper extract and preparation method thereof and AntiHIV1 RT activity application |
| CN108926588B (en) * | 2018-08-22 | 2021-07-27 | 广西医科大学 | Euonymus fortunei extract, preparation method thereof and anti-HIV application thereof |
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