CN104436218A - Gastrointestinal contrast agent containing traditional Chinese medicine extract - Google Patents
Gastrointestinal contrast agent containing traditional Chinese medicine extract Download PDFInfo
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- CN104436218A CN104436218A CN201410802035.7A CN201410802035A CN104436218A CN 104436218 A CN104436218 A CN 104436218A CN 201410802035 A CN201410802035 A CN 201410802035A CN 104436218 A CN104436218 A CN 104436218A
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- 239000000284 extract Substances 0.000 title claims abstract description 52
- 239000002872 contrast media Substances 0.000 title claims abstract description 29
- 230000002496 gastric effect Effects 0.000 title claims abstract description 25
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 claims abstract description 24
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- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 11
- 229930195725 Mannitol Natural products 0.000 claims abstract description 10
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- 235000007716 Citrus aurantium Nutrition 0.000 claims abstract 2
- 235000005976 Citrus sinensis Nutrition 0.000 claims abstract 2
- 241000218236 Cannabis Species 0.000 claims description 12
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- 240000008669 Hedera helix Species 0.000 claims description 12
- 239000009636 Huang Qi Substances 0.000 claims description 12
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- 241000180649 Panax notoginseng Species 0.000 claims description 12
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- 239000012467 final product Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
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- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
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- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a gastrointestinal contrast agent containing a traditional Chinese medicine extract. The gastrointestinal contrast agent is prepared from the following components in parts by weight: 55-75 parts of barium sulfate, 5-15 parts of the traditional Chinese medicine extract and 20 parts of mannitol, wherein the traditional Chinese medicine extract is prepared by the following steps: taking 25 parts of tuber fleeceflower stems, 15 parts of polygala tenuifolia, 10 parts of rhizoma acori graminei, 8 parts of cynanchum auriculatum, 25 parts of seville orange flowers, 15 parts of emblic leafflower fruits, 25 parts of hawthorn, 10 parts of white hyacinth beans, 10 parts of edestan, 15 parts of radix curcumae, 25 parts of astragalus membranaceus, 15 parts of codonopsis pilosula, 15 parts of sedum sarmentosum, 15 parts of pseudo-ginseng and 25 parts of liquorice; mixing; soaking with water; decocting; filtering to obtain a filtrate; and drying the filtrate to obtain the gastrointestinal contrast agent. The gastrointestinal contrast agent disclosed by the invention has the beneficial effects of shortening the inspection time, relieving the side effects brought by X-ray inspection, has a maintaining or health-care effect on stomach, liver and the like and is good in using effect.
Description
Technical field
The present invention relates to a kind of for radiology department, containing the gastrointestinal contrast agent of Chinese medicine extract.
Background technology
Barium meal and digestive tract barium meal, refer to and use barium sulfate as contrast agent, show a kind of inspection method of digestive tract with or without pathological changes under roentgen radiation x.When x-ray checks, because the density of the various organ of human body, tissue is different with thickness, so demonstrate the natural layer contrast of black and white.But at some position of human body, especially abdominal part, because the density broadly similar of inner good several organ, tissue, must import harmless contrast agent (as medicinal barium sulfate), improve display comparison degree artificially, just can reach desirable Checking on effect.This inspection method is called x-ray contrast examination clinically.When doing barium examination, barium agent will be eaten into by the people first checked, accepts gastrointestinal tract X-ray examination simultaneously.Gastrointestinal contrast agent of the prior art (barium meal) function singleness, to body without taking good care of, health-care effect.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of gastrointestinal contrast agent containing Chinese medicine extract, its side effect is low, takes good care of, health-care effect to body, and can strengthen gastrointestinal tract tensile force, promotes to wriggle, makes barium agent quickly by small intestinal, shorten the review time.
The present invention is achieved by the following technical solutions:
Containing a gastrointestinal contrast agent for Chinese medicine extract, be made up of the component of following weight portion: 55 ~ 75 parts, barium sulfate, Chinese medicine extract 5 ~ 15 parts, 20 parts, mannitol;
Wherein, Chinese medicine extract is obtained by following preparation method: get Caulis Polygoni Multiflori 20 ~ 30 parts, Radix Polygalae 10 ~ 20 parts, Rhizoma Acori Graminei 5 ~ 15 parts, Radix Cynanchi Auriculati 5 ~ 10 parts, CitrusaurantiumL.Var.amara Engl. 20 ~ 30 parts, Fructus Phyllanthi 10 ~ 20 parts, Fructus Crataegi 20 ~ 30 parts, Semen Lablab Album 5 ~ 15 parts, Fructus Cannabis 5 ~ 15 parts, Radix Curcumae 10 ~ 20 parts, the Radix Astragali 20 ~ 30 parts, Radix Codonopsis 10 ~ 20 parts, Herba Sedi 10 ~ 20 parts, Radix Notoginseng 10 ~ 20 parts and 20 ~ 30 parts, Radix Glycyrrhizae, mixing, add water to submerge, decoct 60 ~ 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract; Described number is weight portion.
Preferably, described Chinese medicine extract is obtained by following preparation method: get Caulis Polygoni Multiflori 25 parts, Radix Polygalae 15 parts, Rhizoma Acori Graminei 10 parts, Radix Cynanchi Auriculati 8 parts, CitrusaurantiumL.Var.amara Engl. 25 parts, Fructus Phyllanthi 15 parts, Fructus Crataegi 25 parts, Semen Lablab Album 10 parts, Fructus Cannabis 10 parts, Radix Curcumae 15 parts, the Radix Astragali 25 parts, Radix Codonopsis 15 parts, Herba Sedi 15 parts, Radix Notoginseng 15 parts and 25 parts, Radix Glycyrrhizae, mixing, add water to submerge, decoct 60 ~ 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
The preparation method of the described gastrointestinal contrast agent containing Chinese medicine extract is: get barium sulfate, Chinese medicine extract and mannitol, and mixing mixing, to obtain final product.
During use, temper, concentration is 50 ~ 80% (w/w), oral or clysis with barium, use amount 150g ~ 300g (calculating by contrast agent consumption).If patient is child, can take the circumstances into consideration to add some flavoring agents, as Icing Sugar, essence, citric acid etc.
Gastrointestinal contrast agent of the present invention, containing Chinese medicine extract, wherein, Caulis Polygoni Multiflori, Radix Polygalae, Rhizoma Acori Graminei, Radix Cynanchi Auriculati compatibility can be alleviated, the Nausea and vomiting reaction that causes when reducing X-radiological survey X.The effect that CitrusaurantiumL.Var.amara Engl., Fructus Phyllanthi, Fructus Crataegi, Semen Lablab Album compatibility can play stomach invigorating, help digestion, the effectively symptom such as inappetence, fatigue and weak after alleviation X-radiological survey X.Fructus Cannabis, Radix Curcumae compatibility can strengthen gastrointestinal tract tensile force, promote to wriggle, and can shorten barium agent running time, (1 ~ 2 hour) can observe whole small intestinal in the short period of time when small bowel examination.The Radix Astragali, Radix Codonopsis play the effect of nourishing the stomach, tonify deficiency.Herba Sedi, Radix Notoginseng compatibility play the effect of nourishing the liver hepatoprotective.Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.Diosmol can make barium agent quickly by small intestinal, can shorten the review time when carrying out small bowel enema.All medicine compatibilities, can play the effect alleviating the symptoms such as Nausea and vomiting, inappetence, fatigue and weak, also have the health-care effect such as stomach invigorating spleen invigorating, nourishing the liver hepatoprotective, also can be conducive to barium agent quickly through small intestinal, shorten the review time.
Gastrointestinal contrast agent containing Chinese medicine extract of the present invention, to clarify a diagnosis human body gastritis, gastric ulcer, gastric cancer, gastroptosis, prolapse of gastric mucosa, duodenal bulbar ulcer, gastrointestinal tumor etc., have no side effect, taking convenience, display, as clear, clinically to be taken through more than 80 examples, respond well, diagnosis is clear and definite, and can alleviate, alleviates or eliminate the symptom such as stomachache, gastric acid, Nausea and vomiting, inappetence, fatigue and weak of patient.
Gastrointestinal contrast agent of the present invention, side effect is low, except there is radiography function, can also play and shorten the review time, alleviate the beneficial effects such as the side effect (Nausea and vomiting, inappetence, fatigue and weak) that X-radiological survey X brings, also can play stomach, liver etc. and take good care of or health-care effect, result of use is better.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1 prepares the gastrointestinal contrast agent containing Chinese medicine extract
Get barium sulfate 130g, Chinese medicine extract 20g, mannitol 40g, mixing mixing, to obtain final product.
Described Chinese medicine extract is obtained by following preparation method: get Caulis Polygoni Multiflori 258, Radix Polygalae 15g, Rhizoma Acori Graminei 10g, Radix Cynanchi Auriculati 8g, CitrusaurantiumL.Var.amara Engl. 25g, Fructus Phyllanthi 15g, Fructus Crataegi 25g, Semen Lablab Album 10g, Fructus Cannabis 10g, Radix Curcumae 15g, Radix Astragali 25g, Radix Codonopsis 15g, Herba Sedi 15g, Radix Notoginseng 15g and Radix Glycyrrhizae 25g, mixing, add water to submerge, decoct 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
During use, temper, concentration 70% (w/w) is advisable, oral or clysis with barium, use amount 150g ~ 300g (calculating by contrast agent consumption).If patient is child, can take the circumstances into consideration to add some flavoring agents, as Icing Sugar, essence, citric acid etc.
Application example: 106 routine patients are checked, the gastrointestinal contrast agent of oral the present embodiment before checking.Result: after inspection, has 14 routine person under inspection's readmes to have the sensation of extremely slightly feeling sick, feeling sick, and after having 9 routine person under inspection's readme inspections, appetite is not very strong, has 92 routine person under inspection's readmes without nauseating, dizzy, vomiting, weak symptom, without sense of discomfort.
Embodiment 2 prepares the gastrointestinal contrast agent containing Chinese medicine extract
Get barium sulfate 110g, Chinese medicine extract 30g, mannitol 40g, mixing mixing, to obtain final product.
Described Chinese medicine extract is obtained by following preparation method: get Caulis Polygoni Multiflori 22g, Radix Polygalae 18g, Rhizoma Acori Graminei 12g, Radix Cynanchi Auriculati 6g, CitrusaurantiumL.Var.amara Engl. 28g, Fructus Phyllanthi 12g, Fructus Crataegi 22g, Semen Lablab Album 12g, Fructus Cannabis 8g, Radix Curcumae 18g, Radix Astragali 28g, Radix Codonopsis 12g, Herba Sedi 12g, Radix Notoginseng 18g and Radix Glycyrrhizae 22g, mixing, add water to submerge, decoct 70min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
Using method is with embodiment 1.
Embodiment 3 prepares the gastrointestinal contrast agent containing Chinese medicine extract
Get barium sulfate 150g, Chinese medicine extract 10g, mannitol 40g, mixing mixing, to obtain final product.
Described Chinese medicine extract is obtained by following preparation method: get Caulis Polygoni Multiflori 28g, Radix Polygalae 12g, Rhizoma Acori Graminei 8g, Radix Cynanchi Auriculati 9g, CitrusaurantiumL.Var.amara Engl. 22g, Fructus Phyllanthi 18g, Fructus Crataegi 28g, Semen Lablab Album 8g, Fructus Cannabis 12g, Radix Curcumae 12g, Radix Astragali 22g, Radix Codonopsis 18g, Herba Sedi 18g, Radix Notoginseng 12g and Radix Glycyrrhizae 28g, mixing, add water to submerge, decoct 75min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
Using method is with embodiment 1.
Embodiment 4 prepares the gastrointestinal contrast agent containing Chinese medicine extract
Get barium sulfate 110g, Chinese medicine extract 20g, mannitol 40g, mixing mixing, to obtain final product.
Described Chinese medicine extract is obtained by following preparation method: get Caulis Polygoni Multiflori 20g, Radix Polygalae 20g, Rhizoma Acori Graminei 5g, Radix Cynanchi Auriculati 10g, CitrusaurantiumL.Var.amara Engl. 20g, Fructus Phyllanthi 20g, Fructus Crataegi 30g, Semen Lablab Album 5g, Fructus Cannabis 5g, Radix Curcumae 20g, Radix Astragali 20g, Radix Codonopsis 20g, Herba Sedi 10g, Radix Notoginseng 20g and Radix Glycyrrhizae 20g, mixing, add water to submerge, decoct 80min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
Using method is with embodiment 1.
Embodiment 5 prepares the gastrointestinal contrast agent containing Chinese medicine extract
Get barium sulfate 110g, Chinese medicine extract 30g, mannitol 40g, mixing mixing, to obtain final product.
Described Chinese medicine extract is obtained by following preparation method: get Caulis Polygoni Multiflori 30g, Radix Polygalae 10g, Rhizoma Acori Graminei 15g, Radix Cynanchi Auriculati 5g, CitrusaurantiumL.Var.amara Engl. 30g, Fructus Phyllanthi 10g, Fructus Crataegi 20g, Semen Lablab Album 15g, Fructus Cannabis 15g, Radix Curcumae 10g, Radix Astragali 30g, Radix Codonopsis 10g, Herba Sedi 20g, Radix Notoginseng 10g and Radix Glycyrrhizae 30g, mixing, add water to submerge, decoct 60min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
Using method is with embodiment 1.
Claims (5)
1., containing a gastrointestinal contrast agent for Chinese medicine extract, it is characterized in that: be made up of the component of following weight portion: 55 ~ 75 parts, barium sulfate, Chinese medicine extract 5 ~ 15 parts, 20 parts, mannitol;
Wherein, Chinese medicine extract is obtained by following preparation method: get Caulis Polygoni Multiflori 20 ~ 30 parts, Radix Polygalae 10 ~ 20 parts, Rhizoma Acori Graminei 5 ~ 15 parts, Radix Cynanchi Auriculati 5 ~ 10 parts, CitrusaurantiumL.Var.amara Engl. 20 ~ 30 parts, Fructus Phyllanthi 10 ~ 20 parts, Fructus Crataegi 20 ~ 30 parts, Semen Lablab Album 5 ~ 15 parts, Fructus Cannabis 5 ~ 15 parts, Radix Curcumae 10 ~ 20 parts, the Radix Astragali 20 ~ 30 parts, Radix Codonopsis 10 ~ 20 parts, Herba Sedi 10 ~ 20 parts, Radix Notoginseng 10 ~ 20 parts and 20 ~ 30 parts, Radix Glycyrrhizae, mixing, add water to submerge, decoct 60 ~ 90min, filter to get filtrate, filtrate reduced in volume postlyophilization, obtains Chinese medicine extract.
2. the gastrointestinal contrast agent containing Chinese medicine extract according to claim 1, it is characterized in that: described Chinese medicine extract is prepared by following: get Caulis Polygoni Multiflori 25 parts, Radix Polygalae 15 parts, Rhizoma Acori Graminei 10 parts, Radix Cynanchi Auriculati 8 parts, CitrusaurantiumL.Var.amara Engl. 25 parts, Fructus Phyllanthi 15 parts, Fructus Crataegi 25 parts, Semen Lablab Album 10 parts, Fructus Cannabis 10 parts, Radix Curcumae 15 parts, the Radix Astragali 25 parts, Radix Codonopsis 15 parts, Herba Sedi 15 parts, Radix Notoginseng 15 parts and 25 parts, Radix Glycyrrhizae, mixing, add water to submerge, decoct, filter to get filtrate, filtrate is dry, obtains Chinese medicine extract.
3. the gastrointestinal contrast agent containing Chinese medicine extract according to claim 1, it is characterized in that: described Chinese medicine extract obtains by the following method: get Caulis Polygoni Multiflori 22g, Radix Polygalae 18g, Rhizoma Acori Graminei 12g, Radix Cynanchi Auriculati 6g, CitrusaurantiumL.Var.amara Engl. 28g, Fructus Phyllanthi 12g, Fructus Crataegi 22g, Semen Lablab Album 12g, Fructus Cannabis 8g, Radix Curcumae 18g, Radix Astragali 28g, Radix Codonopsis 12g, Herba Sedi 12g, Radix Notoginseng 18g and Radix Glycyrrhizae 22g, mixing, decoct with water, filter to get filtrate, filtrate is dry, obtains Chinese medicine extract.
4. the gastrointestinal contrast agent containing Chinese medicine extract according to claim 1, it is characterized in that: described Chinese medicine extract is prepared by following: get Caulis Polygoni Multiflori 28g, Radix Polygalae 12g, Rhizoma Acori Graminei 8g, Radix Cynanchi Auriculati 9g, seville orange flower 22g, Fructus Phyllanthi 18g, Fructus Crataegi 28g, Semen Lablab Album 8g, Fructus Cannabis 12g, Radix Curcumae 12g, Radix Astragali 22g, Radix Codonopsis 18g, Herba Sedi 18g, Radix Notoginseng 12g and Radix Glycyrrhizae 28g, mixing, decoct with water, filter to get filtrate, filtrate is dry, obtains Chinese medicine extract.
5. the preparation method of the gastrointestinal contrast agent containing Chinese medicine extract described in Claims 1 to 4, is characterized in that: get barium sulfate, Chinese medicine extract and mannitol, and mixing mixing, to obtain final product.
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| CN104740657A (en) * | 2015-04-16 | 2015-07-01 | 张国明 | Gastrointestinal tract developing agent and preparation method thereof |
| CN104758953A (en) * | 2015-03-24 | 2015-07-08 | 青岛大学附属医院 | Gastrointestinal tract contrast agent |
| CN109432447A (en) * | 2018-11-29 | 2019-03-08 | 天津凯茵科技有限公司 | Contrast agent for alimentary canal X-ray examination |
| CN110051774A (en) * | 2019-04-22 | 2019-07-26 | 重庆医科大学附属永川医院 | The reagent and preparation method thereof of contrast agent discharge in a kind of promotion human body |
| CN111735415A (en) * | 2020-05-20 | 2020-10-02 | 迪马新材料科技（苏州）有限公司 | Method for rapidly identifying bonding state of bonding surface of adhesive |
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| CN104740657A (en) * | 2015-04-16 | 2015-07-01 | 张国明 | Gastrointestinal tract developing agent and preparation method thereof |
| CN109432447A (en) * | 2018-11-29 | 2019-03-08 | 天津凯茵科技有限公司 | Contrast agent for alimentary canal X-ray examination |
| CN109432447B (en) * | 2018-11-29 | 2021-07-23 | 西南医科大学附属中医医院 | Contrast agent for X-ray examination of the digestive tract |
| CN110051774A (en) * | 2019-04-22 | 2019-07-26 | 重庆医科大学附属永川医院 | The reagent and preparation method thereof of contrast agent discharge in a kind of promotion human body |
| CN111735415A (en) * | 2020-05-20 | 2020-10-02 | 迪马新材料科技（苏州）有限公司 | Method for rapidly identifying bonding state of bonding surface of adhesive |
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