CN101342360B - Chinese medicinal composition for treating esophagus cancer - Google Patents

Chinese medicinal composition for treating esophagus cancer Download PDF

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Publication number
CN101342360B
CN101342360B CN2008101388894A CN200810138889A CN101342360B CN 101342360 B CN101342360 B CN 101342360B CN 2008101388894 A CN2008101388894 A CN 2008101388894A CN 200810138889 A CN200810138889 A CN 200810138889A CN 101342360 B CN101342360 B CN 101342360B
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herba
chinese medicine
treatment
rhizoma
herb
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CN101342360A (en
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张同春
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Zhang Dianzhi
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Abstract

The present invention discloses a Chinese medicine combination for curing esophageal cancer and a preparation method thereof. The Chinese medicine combination contains the following weight proportion of traditional Chinese medicinal herb materials: 19g of bittersweet herb, 10g of Indian mockstrawberry herb, 7g of Indian buead, 10g of tangerine peel, 10g of inula flower, 10g of barbed skullcap herb, 20g of spreading hedyotis herb, 3g of chinaroot greenbrier rhizome, 4g of gecko, 20g of Chinese date, 20g of rhizoma zingiberis recens, 10g of arisaema cum bile, 10g of red ochre, 3g of toad, 10g of ginseng and 10g of pinellia tuber. In the preparation method, the impurities of medicinal materials are removed, the gecko is first baked and pulverized for later use, all the medicinal materials are then immersed into water and decocted, liquor is filtered out to remove dregs, and after two filtrates are combined, the gecko powder is put into the filtrate, which is then uniformly stirred until decoction is prepared. Each of the materials is pulverized into powder of 200 to 500 meshes, and all the medicinal powders are uniformly mixed to prepare a powder preparation. The combination of the traditional Chinese medicinal herb materials, which is aimed at the treatment of both symptom and root cause, can enhance the immunity of the human body and prevent cancer cells from metastasizing to other viscera, so that a tumour finally shrinks and is gradually disappeared, and at the same time, the esophagus become expedite, so that eating and drinking can return to normal.

Description

A kind of Chinese medicine composition for the treatment of esophageal carcinoma
Technical field
The present invention relates to medicine, be a kind of be a kind of Chinese medicine composition for the treatment of esophageal carcinoma and preparation method thereof of raw material with the Chinese herbal medicine.
Background technology
It is reported that because the esophageal carcinoma sickness rate that multiple factors such as diet and environmental pollution cause rises year by year, the treatment means that the patient adopts mainly is an operative treatment.Because the methods such as chemotherapy behind the operative treatment are bigger to the damaging effect of human body, and its survival rate is relatively low, so some patient selects treatment by Chinese herbs for use, to avoid the misery in the operative treatment.The Chinese medicine of having reported the treatment esophageal carcinoma has multiple medicine, but its curative effect has than big difference, and produce effects is slower.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of esophageal carcinoma and preparation method thereof, it adopts the method for the treatment of both the principal and secondary aspects of a disease, and strengthening vital QI to eliminate pathogenic factors reaches the purpose for the treatment of esophageal carcinoma.
The present invention for achieving the above object, be achieved through the following technical solutions: a kind of Chinese medicine composition for the treatment of esophageal carcinoma, form by the raw material of Chinese medicine of following weight ratio: Herba Solani Lyrati 5-25g, Herba Duchesneae Indicae 5-15g, Poria 5-10g, Pericarpium Citri Reticulatae 5-15g, Flos Inulae 5-15g, Herba Scutellariae Barbatae 5-15g, Herba Hedyotidis Diffusae 5-35g, Rhizoma Smilacis Chinensis 1-4.5g, Gekko Swinhonis 3-6g, Fructus Jujubae 5-35g, Rhizoma Zingiberis Recens 5-35g, Arisaema Cum Bile 5-15g, Haematitum 5-15g, Bufo siccus 0.5-5g, Radix Ginseng 5-15g and Rhizoma Pinelliae 5-15g.
A kind of Chinese medicine composition for the treatment of esophageal carcinoma of the present invention, it can be made up of the raw material of Chinese medicine of following weight ratio: Herba Solani Lyrati 25g, Herba Duchesneae Indicae 15g, Poria 10g, Pericarpium Citri Reticulatae 15g, Flos Inulae 15g, Herba Scutellariae Barbatae 15g, Herba Hedyotidis Diffusae 35g, Rhizoma Smilacis Chinensis 4.5g, Gekko Swinhonis 6g, Fructus Jujubae 35g, Rhizoma Zingiberis Recens 35g, Arisaema Cum Bile 15g, Haematitum 15g, Bufo siccus 5g, Radix Ginseng 15g and Rhizoma Pinelliae 15g.
Described a kind of Chinese medicine composition for the treatment of esophageal carcinoma, preferred scheme is to adopt the raw material of Chinese medicine of following weight ratio to form: Herba Solani Lyrati 19g, Herba Duchesneae Indicae 10g, Poria 7g, Pericarpium Citri Reticulatae 10g, Flos Inulae 10g, Herba Scutellariae Barbatae 10g, Herba Hedyotidis Diffusae 20g, Rhizoma Smilacis Chinensis 3g, Gekko Swinhonis 4g, Fructus Jujubae 20g, Rhizoma Zingiberis Recens 20g, Arisaema Cum Bile 10g, Haematitum 10g, Bufo siccus 3g, Radix Ginseng 10g and Rhizoma Pinelliae 10g.
A kind of Chinese medicine composition for the treatment of esophageal carcinoma of the present invention, further preferred scheme is to adopt the raw material of Chinese medicine of following weight ratio to form: Herba Solani Lyrati 16g, Herba Duchesneae Indicae 7g, Poria 6g, Pericarpium Citri Reticulatae 7g, Flos Inulae 7g, Herba Scutellariae Barbatae 7g, Herba Hedyotidis Diffusae 15g, Rhizoma Smilacis Chinensis 2g, Gekko Swinhonis 3g, Fructus Jujubae 15g, Rhizoma Zingiberis Recens 15g, Arisaema Cum Bile 7g, Haematitum 7g, Bufo siccus 2g, Radix Ginseng 7g and Rhizoma Pinelliae 7g.
A kind of Chinese medicine composition for the treatment of esophageal carcinoma of the present invention, described dosage form is decoction or powder.
A kind of preparation method for the treatment of the Chinese medicine composition of esophageal carcinoma of the present invention, with described each crude drug decontamination, earlier Gekko Swinhonis is dried grind into powder standby, again each crude drug was immersed in 450-600 ml water 40-60 minute, decocted 20-25 minute, after the filtrate, medicinal residues add 150-200 milliliter decocting 15 minutes, the filtrate waste is inserted the Gekko Swinhonis powder to stir in the filtrate after twice filtrate merged and is made decoction.
A kind of preparation method for the treatment of the Chinese medicine composition of esophageal carcinoma of the present invention, with described each selection of crude drugs decontamination, clean oven dry, Gekko Swinhonis is dried grind into powder earlier, again other each crude drug is ground into 200-500 order powder, each powder medicine mix homogeneously is made powderous preparations.
The pharmaceutical composition that the present invention selects for use, treating both the principal and secondary aspects of a disease is a purpose to strengthen autoimmunity and to be aided with detoxifcation, the anticancer diffusion makes finally that tumor is dwindled, the unimpeded normal feed of esophagus.
Each crude drug mainly acts on and is in the Chinese medicine composition of the present invention: Herba Solani Lyrati is used for heat-clearing and toxic substances removing; Herba Duchesneae Indicae is used for clearing away heat and cooling blood, subduing swelling and detoxicating; Poria is used for the sharp key of eliminating dampness by diuresis, drying dampness to eliminate phlegm; Pericarpium Citri Reticulatae is used for the intestinal stasis relieving expectorant, the logical the five internal organs of a surname; Flos Inulae is used for expectorant row water preventing or arresting vomiting to be told, and soft painful abdominal mass is hard; Herba Scutellariae Barbatae is used for dispersing swelling and dissipating binds, and dispelling silt hemostasis relieves internal heat; Herba Hedyotidis Diffusae is used for the blood circulation promoting and blood stasis dispelling heat-clearing and toxic substances removing; Rhizoma Smilacis Chinensis is used for dispersing swelling and dissipating binds, heat-clearing and toxic substances removing; Gekko Swinhonis is used to dispel the wind, eliminating stagnation, detoxifcation; Fructus Jujubae is used for replenishing blood and nourishing liver, QI invigorating tonify deficiency, strengthening vital QI to eliminate pathogenic factors, coordinating the actions of various ingredients in a prescription; Rhizoma Zingiberis Recens is used to the cold expelling that induces sweat; The Rhizoma Pinelliae is used for drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Arisaema Cum Bile is used for removing heat-phlegm; It is contrary that Haematitum is used for the suppressing the hyperactive liver town, cooling blood for hemostasis; Radix Ginseng is used for the QI invigorating tonification; Bufo siccus is used for detoxifcation, pain relieving.
Above-mentioned each medicine combination is used for hard masses softening and resolving, and clearing heat for detumescence, detoxifcation, strengthening vital QI to eliminate pathogenic factors etc. are purpose with the treating both the principal and secondary aspects of a disease, strengthen body immunity, and cancerous cell is not shifted to other internal organs, tumor is dwindled slowly disappear the unimpeded normal diet of esophagus.
Medicine of the present invention has the curative effect of highly significant to esophageal carcinoma, takes proof through clinical 761 routine patients, and the back produce effects of taking medicine is fast, general 4-10 days begin and can take food, the 725 routine patients obviously stimulating appetite of taking medicine after 1-2 the course of treatment wherein, the transference cure of various influences feeds, 643 routine patients took medicine after 3-4 the course of treatment, antisecosis, weight increase, the mental status return to the preceding situation of disease, and be unimpeded through X-ray and CT examination esophagus, do not find cancer cell metastasis, with asking not recurrence in 1 year.
Medicine of the present invention can only increase its appetite to the uncontrollable cancer cell metastasis of patient of advanced esophageal cancer cancerous cell diffusion.Drug powder of the present invention is taken 3 times every day, each 8 grams, and 20 days is a course of treatment.Medicine decoction of the present invention is one pair of every day, and 20 days is a course of treatment.Period in a medicine is avoided maror.
The specific embodiment
Embodiment
Chinese medicine composition of the present invention can have multiple combination, illustrates to be made up of following multiple Chinese medicinal raw materials in proportion by weight:
1, Herba Solani Lyrati 19g, Herba Duchesneae Indicae 10g, Poria 7g, Pericarpium Citri Reticulatae 10g, Flos Inulae 10g, Herba Scutellariae Barbatae 10g, Herba Hedyotidis Diffusae 20g, Rhizoma Smilacis Chinensis 3g, Gekko Swinhonis 4g, Fructus Jujubae 20g, Rhizoma Zingiberis Recens 20g, Arisaema Cum Bile 10g, Haematitum 10g, Bufo siccus 3g, Radix Ginseng 10g and Rhizoma Pinelliae 10g.
2, Herba Solani Lyrati 16g, Herba Duchesneae Indicae 7g, Poria 6g, Pericarpium Citri Reticulatae 7g, Flos Inulae 7g, Herba Scutellariae Barbatae 7g, Herba Hedyotidis Diffusae 15g, Rhizoma Smilacis Chinensis 2g, Gekko Swinhonis 3g, Fructus Jujubae 15g, Rhizoma Zingiberis Recens 15g, Arisaema Cum Bile 7g, Haematitum 7g, Bufo siccus 2g, Radix Ginseng 7g and Rhizoma Pinelliae 7g.
3, Herba Solani Lyrati 5g, Herba Duchesneae Indicae 5g, Poria 5g, Pericarpium Citri Reticulatae 5g, Flos Inulae 5g, Herba Scutellariae Barbatae 5g, Herba Hedyotidis Diffusae 5g, Rhizoma Smilacis Chinensis 1g, Gekko Swinhonis 3g, Fructus Jujubae 5g, Rhizoma Zingiberis Recens 5g, Arisaema Cum Bile 5g, Haematitum 5g, Bufo siccus 0.5g, Radix Ginseng 5g and Rhizoma Pinelliae 5g.
4, Herba Solani Lyrati 25g, Herba Duchesneae Indicae 15g, Poria 10g, Pericarpium Citri Reticulatae 15g, Flos Inulae 15g, Herba Scutellariae Barbatae 15g, Herba Hedyotidis Diffusae 35g, Rhizoma Smilacis Chinensis 4.5g, Gekko Swinhonis 6g, Fructus Jujubae 35g, Rhizoma Zingiberis Recens 35g, Arisaema Cum Bile 15g, Haematitum 15g, Bufo siccus 5g, Radix Ginseng 15g and Rhizoma Pinelliae 15g.
A kind of preparation method for the treatment of the Chinese medicine composition of esophageal carcinoma of the present invention, with described each crude drug decontamination, earlier Gekko Swinhonis is dried grind into powder standby, again each crude drug was immersed in 450-600 ml water 40-60 minute, decocted 20-25 minute, after the filtrate, medicinal residues add 150-200 milliliter decocting 15 minutes, the filtrate waste is inserted the Gekko Swinhonis powder to stir in the filtrate after twice filtrate merged and is made decoction.
A kind of preparation method for the treatment of the Chinese medicine composition of esophageal carcinoma of the present invention, with described each selection of crude drugs decontamination, clean oven dry, Gekko Swinhonis is dried grind into powder earlier, again other each crude drug is ground into 200-500 order powder, each powder medicine mix homogeneously is made powderous preparations.
Model case:
Case 1, the lijin field, the man, 77 years old now, the peasant was Heze, Shandong Paeonia suffruticosa people.In December, 2006, patient's resistance is choked, and dysphagia is with making digestive tract X ray examination to Heze, Shandong Province municipal hospital, be diagnosed as esophageal carcinoma (hypomere), make a definite diagnosis no radiotherapy chemotherapy in back and operation, back symptom increases the weight of gradually, feed pain occurs, can not take food, vomiting after eating, vomitus is a gastric content, body constitution is become thin gradually.Came me institute to go to a doctor on February 18th, 2008, the patient takes decoction medicine of the present invention, in the time of the 4th day, the black loose stool of suffering from diarrhoea 2 times, feed pain before increases the weight of, be thought of as due to tumor cell comes off, the patient refuses treatment, adheres to continuing to take medicine under the advice its daughter, take medicine 14 days the time, spirit takes a turn for the better, and can take food on a small quantity, and feed pain obviously alleviates, the patient just can normally take food after taking medicine 20 days, feed stops companion's pain relief, and the patient does not have any discomfort symptom after taking medicine 30 days, continues to strengthen treatment and fully recovers after 1 course of treatment.Patient's mental status is good, eats all without hindrance sense of choking of various foods, weight increase, and the X-ray examination esophagus is unobstructed.
Case 2, Qiao Fangming, the man, 74 years old is Heze, Shandong Dingyao County Qiao Zhuan people.In March, 2007, the patient does not have obvious inducement and dysphagia occurs, and foreign body sensation is arranged.The X-ray sheet is diagnosed as esophageal carcinoma in Heze, Shandong city hospital, and pathologic finding is the esophagus scale cancer.Taking the conservative medication symptom does not have alleviation, and increases the weight of gradually, sensation of oppression over the chest with shortness of breath occurs, and cough is coughed up phlegm, and for the sticking expectorant of white foam sample, can not normally take food, and body constitution is become thin gradually.JIUYUE came me institute to go to a doctor on the 29th in 2007, and the patient takes powder of the present invention and suffers from diarrhoea the orange colour loose stool in the time of the 4th day for several times, and Trichiurus haumela squama sample flakelet still can not be taken food, nausea and vomiting, and spirit is poor, the normal reaction that this comes off for tumor.The nausea and vomiting transference cure the 18th day time of taking medicine can be taken food on a small quantity, and spirit takes a turn for the better.Take medicine after the 2nd course of treatment, the patient can normally take food, and stool is normal, and the symptom of breathing hard obviously alleviates, and patient's diet is normal after the course of treatment of continuing to take medicine, antisecosis, and Shandong Province on the 22nd Heze municipal hospital digestive tract X-ray check February in 2008: esophagus is unobstructed.

Claims (4)

1. Chinese medicine composition for the treatment of esophageal carcinoma, it is characterized in that: the raw material of Chinese medicine by the following weight ratio is formed: Herba Solani Lyrati 5-25g, Herba Duchesneae Indicae 5-15g, Poria 5-10g, Pericarpium Citri Reticulatae 5-15g, Flos Inulae 5-15g, Herba Scutellariae Barbatae 5-15g, Herba Hedyotidis Diffusae 5-35g, Rhizoma Smilacis Chinensis 1-4.5g, Gekko Swinhonis 3-6g, Fructus Jujubae 5-35g, Rhizoma Zingiberis Recens 5-35g, Arisaema Cum Bile 5-15g, Haematitum 5-15g, Bufo siccus 0.5-5g, Radix Ginseng 5-15g and Rhizoma Pinelliae 5-15g.
2. a kind of Chinese medicine composition for the treatment of esophageal carcinoma according to claim 1 is characterized in that: the raw material of Chinese medicine by the following weight ratio is formed: Herba Solani Lyrati 25g, Herba Duchesneae Indicae 15g, Poria 10g, Pericarpium Citri Reticulatae 15g, Flos Inulae 15g, Herba Scutellariae Barbatae 15g, Herba Hedyotidis Diffusae 35g, Rhizoma Smilacis Chinensis 4.5g, Gekko Swinhonis 6g, Fructus Jujubae 35g, Rhizoma Zingiberis Recens 35g, Arisaema Cum Bile 15g, Haematitum 15g, Bufo siccus 5g, Radix Ginseng 15g and Rhizoma Pinelliae 15g.
3. a kind of Chinese medicine composition for the treatment of esophageal carcinoma according to claim 1 is characterized in that: the raw material of Chinese medicine by the following weight ratio is formed: Herba Solani Lyrati 19g, Herba Duchesneae Indicae 10g, Poria 7g, Pericarpium Citri Reticulatae 10g, Flos Inulae 10g, Herba Scutellariae Barbatae 10g, Herba Hedyotidis Diffusae 20g, Rhizoma Smilacis Chinensis 3g, Gekko Swinhonis 4g, Fructus Jujubae 20g, Rhizoma Zingiberis Recens 20g, Arisaema Cum Bile 10g, Haematitum 10g, Bufo siccus 3g, Radix Ginseng 10g and Rhizoma Pinelliae 10g.
4. a kind of Chinese medicine composition for the treatment of esophageal carcinoma according to claim 1 is characterized in that: the raw material of Chinese medicine by the following weight ratio is formed: Herba Solani Lyrati 16g, Herba Duchesneae Indicae 7g, Poria 6g, Pericarpium Citri Reticulatae 7g, Flos Inulae 7g, Herba Scutellariae Barbatae 7g, Herba Hedyotidis Diffusae 15g, Rhizoma Smilacis Chinensis 2g, Gekko Swinhonis 3g, Fructus Jujubae 15g, Rhizoma Zingiberis Recens 15g, Arisaema Cum Bile 7g, Haematitum 7g, Bufo siccus 2g, Radix Ginseng 7g and Rhizoma Pinelliae 7g.
CN2008101388894A 2008-08-08 2008-08-08 Chinese medicinal composition for treating esophagus cancer Expired - Fee Related CN101342360B (en)

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN109419968A (en) * 2017-08-21 2019-03-05 邓泽潭 A kind of oral traditional Chinese medicine composition for treating the cancer of the esophagus

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CN102166337A (en) * 2011-03-31 2011-08-31 青岛大学 Ginger and inula flower composition as well as preparation method and application thereof in preparation of toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer
CN106075195A (en) * 2016-08-04 2016-11-09 菏泽海诺知识产权服务有限公司 A kind of decoction treating esophageal carcinoma
CN106334165A (en) * 2016-11-28 2017-01-18 广西慧投互联网金融服务有限公司 Traditional Chinese medicine composition capable of nursing esophagus cancer

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