CN103330914B - Traditional Chinese medicine composition for treating chronic gastritis - Google Patents
Traditional Chinese medicine composition for treating chronic gastritis Download PDFInfo
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- CN103330914B CN103330914B CN201310262417.0A CN201310262417A CN103330914B CN 103330914 B CN103330914 B CN 103330914B CN 201310262417 A CN201310262417 A CN 201310262417A CN 103330914 B CN103330914 B CN 103330914B
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Abstract
The invention relates to a traditional Chinese medicine composition for treating chronic gastritis. The composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-20 parts of radix bupleuri, 10-30 parts of angelica sinensis, 20-40 parts of white paeony root, 20-40 parts of poria, 20-40 parts of largehead atractylodes rhizome, 5-15 parts of turmeric root tuber, 5-15 parts of nutgrass galingale rhizome, 5-15 parts of common aucklandia root, 10-30 parts of rhizoma corydalis, 10-20 parts of orange fruit, 5-15 parts of fructus amomi, 5-15 parts of pinellia tuber, 5-15 parts of immature tangerine peel, 5-15 parts of platycodon root, 20-40 parts of salvia miltiorrhiza, 10-30 parts of Sichuan lovage rhizome, 5-15 parts of cortex magnoliae officinalis, 20-40 parts of lily, 5-15 parts of thunberg fritillary bulb, 3-10 parts of liquorice and 5-25 parts of Chinese dates. The traditional Chinese medicine composition has the functions of soothing the liver and regulating the circulation of qi, invigorating the spleen and tonifying the stomach, promoting qi circulation to relieve pain and activating stagnancy to eliminate swelling, has obvious curative effects on chronic gastritis and reliable functions, is wide in component sources and simple and convenient to prepare and has no toxic or side effect.
Description
Technical field
The present invention relates to a kind of not medicinal preparation of definite structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of chronic gastritis.
Background technology
Chronic gastritis is a kind of very common digestive tract disease, the chronic gastropathy that the non-specific chronic inflammatory disease of gastric mucosa of take is main pathological change.Pathological changes can be confined to a part for stomach, and whole stomach also can permeate.According to the Histological change of gastric mucosa, can divide shallow, atrophic, plumpness three types.Total symptom is clinically: the vexed swollen pain of epigastrium, belch are frequent, pantothenic acid, loss of appetite, become thin, the disease such as diarrhoea.Doctor trained in Western medicine is needing symptomatic treatment aspect treatment chronic gastritis.For example, there is patient glutted, nauseating, vomiting, available metoclopramide, motilium; Dyspeptic patient, can take polyzyme tablets, multiple probiotic bacteria etc.; With the patient of bile reflux, except application medicine for stomach dynamic (as motilium) is in case bile reflux, also should use in some and the medicine of bile, as bangxiaoan; To the patient of stomach spasm, can use Semen daturae tablet, 654-2 with relieving spasm to stop pain; And have the patient of acid regurgitation, stomachache, can apply PPI preparation etc. and treat.But patient easily produces dependency to the Western medicine for the treatment of chronic gastritis, after drug withdrawal, the state of an illness is prone to repeatedly, and the long-term direct effect internal organs of Western medicine, the side effect easily bringing to human body.
Chronic gastritis is modal gastropathy, belongs to the sick categories such as Chinese medicine " gastric abscess ", " feeling of fullness ", " acid regurgitation ", " noisy ", " indigestion and loss of appetite ".
The traditional Chinese medical science thinks, chronic gastritis many because of long-term feelings will unsuccessful, eating and drinking without temperance, work and rest is not normal, causes depression of liver-QI, dysfunction of the spleen in transportation, gastral cavilty is become estranged, with the passing of time middle gas virtual loss, thus cause all symptoms.
According to theory of Chinese medical science, for the pathogeny of chronic gastritis, take liver-smoothing, qi-regulating, invigorating spleen and reinforcing stomach, dyspepsia and intestinal stasis relieving is the rule for the treatment of, carries out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome prior art western medicines in treatment chronic gastritis, exist after drug withdrawal easily repeatedly and the large deficiency of side effect, the invention provides a kind ofly prepare conveniently, medicine source is wide, cost is low, the Chinese medicine composition of evident in efficacy, reliable effect, the treatment chronic gastritis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of chronic gastritis, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Bupleuri 10-20 part, Radix Angelicae Sinensis 10-30 part, Radix Paeoniae Alba 20-40 part, Poria 20-40 part, Rhizoma Atractylodis Macrocephalae 20-40 part, Radix Curcumae 5-15 part, Rhizoma Cyperi 5-15 part, Radix Aucklandiae 5-15 part, Rhizoma Corydalis 10-30 part, Fructus Aurantii 10-20 part, Fructus Amomi 5-15 part, Rhizoma Pinelliae 5-15 part, Pericarpium Citri Reticulatae Viride 5-15 part, Radix Platycodonis 5-15 part, Radix Salviae Miltiorrhizae 20-40 part, Rhizoma Chuanxiong 10-30 part, Cortex Magnoliae Officinalis 5-15 part, Bulbus Lilii 20-40 part, Bulbus Fritillariae Thunbergii 5-15 part, Radix Glycyrrhizae 3-10 part and Fructus Jujubae 5-25 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of chronic gastritis, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 15 parts, 15 parts of Radix Bupleuri, 20 parts of Radix Angelicae Sinensis, 30 parts of the Radix Paeoniae Albas, 30 parts of Poria, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Radix Curcumaes, 10 parts of Rhizoma Cyperis, 10 parts of the Radix Aucklandiae, 20 parts of Rhizoma Corydalis, 15 parts of Fructus Aurantiis, 10 parts of Fructus Amomis, 10 parts of the Rhizoma Pinelliaes, 10 parts, Pericarpium Citri Reticulatae Viride, 10 parts of Radix Platycodoniss, 30 parts of Radix Salviae Miltiorrhizaes, 20 parts of Rhizoma Chuanxiongs, 10 parts of Cortex Magnoliae Officinalis, 30 parts of Bulbus Liliies, 10 parts of Bulbus Fritillariae Thunbergiis, 6 parts, Radix Glycyrrhizae and Fructus Jujubae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix Bupleuri have evacuate bring down a fever, the effect of yang invigorating soothing liver-QI; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation; The Radix Paeoniae Alba has the effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Poria has promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, and mind tranquilizing and the heart calming, anticancer effect relieves internal heat; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis; Radix Curcumae has the effect of regulating qi to disperse stagnation, heart fire-clearing upset-relieving; Rhizoma Cyperi has the effect of the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving; Rhizoma Cyperi has the effect of liver-smoothing, qi-regulating, resolving depression pain relieving; The Radix Aucklandiae has the effect of intestinal stasis relieving in promoting the circulation of QI to relieve pain, tune; Rhizoma Corydalis has the effect of promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving; Fructus Aurantii has the effect of regulating the flow of QI to ease the stomach, the stagnant relieving distension of row; Fructus Amomi has removing dampness appetizing, warming spleen and stopping diarrha, the antiabortive effect of regulating the flow of vital energy; The Rhizoma Pinelliae has drying dampness to eliminate phlegm, the effect of stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Pericarpium Citri Reticulatae Viride has soothing the liver dispelling the stagnated QI, the stagnant effect of removing food stagnancyization; Radix Platycodonis has lung qi dispersing and eliminates the phlegm, fosters the spirit of nobility and enrich blood, sharp the five internal organs, mend the effect of five kinds of over strain; Radix Salviae Miltiorrhizae has the effect of promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Rhizoma Chuanxiong has the effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Cortex Magnoliae Officinalis has circulation of qi promoting removing food stagnancy, dampness except effect full, lowering the adverse QI to relieve asthma; Bulbus Lilii has the effect of nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization, nourishing essence-blood; Bulbus Fritillariae Thunbergii has removing heat-phlegm, the effect of powder detoxifcation; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription; Fructus Jujubae has the effect of invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays altogether the effect of liver-smoothing, qi-regulating, invigorating spleen and reinforcing stomach, promoting the circulation of QI to relieve pain, the stagnant relieving distension of row, chronic gastritis reached to the object for the treatment of both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, does not occur toxic and side effects, total effective rate 92%, cure rate reaches 64%.
The specific embodiment
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 15g, Radix Angelicae Sinensis 20g, Radix Paeoniae Alba 30g, Poria 30g, Rhizoma Atractylodis Macrocephalae 30g, Radix Curcumae 10g, Rhizoma Cyperi 10g, Radix Aucklandiae 10g, Rhizoma Corydalis 20g, Fructus Aurantii 15g, Fructus Amomi 10g, Rhizoma Pinelliae 10g, Pericarpium Citri Reticulatae Viride 10g, Radix Platycodonis 10g, Radix Salviae Miltiorrhizae 30g, Rhizoma Chuanxiong 20g, Cortex Magnoliae Officinalis 10g, Bulbus Lilii 30g, Bulbus Fritillariae Thunbergii 10g, Radix Glycyrrhizae 6g and Fructus Jujubae 15g.
Embodiment 2
Treat a Chinese medicine composition for chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 10g, Radix Angelicae Sinensis 30g, Radix Paeoniae Alba 20g, Poria 40g, Rhizoma Atractylodis Macrocephalae 20g, Radix Curcumae 15g, Rhizoma Cyperi 5g, Radix Aucklandiae 15g, Rhizoma Corydalis 10g, Fructus Aurantii 20g, Fructus Amomi 5g, Rhizoma Pinelliae 15g, Pericarpium Citri Reticulatae Viride 5g, Radix Platycodonis 15g, Radix Salviae Miltiorrhizae 20g, Rhizoma Chuanxiong 30g, Cortex Magnoliae Officinalis 5g, Bulbus Lilii 40g, Bulbus Fritillariae Thunbergii 5g, Radix Glycyrrhizae 10g and Fructus Jujubae 20g.
Embodiment 3
Treat a Chinese medicine composition for chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 20g, Radix Angelicae Sinensis 10g, Radix Paeoniae Alba 40g, Poria 20g, Rhizoma Atractylodis Macrocephalae 40g, Radix Curcumae 5, Rhizoma Cyperi 15g, Radix Aucklandiae 5g, Rhizoma Corydalis 30g, Fructus Aurantii 10g, Fructus Amomi 15g, Rhizoma Pinelliae 5g, Pericarpium Citri Reticulatae Viride 15g, Radix Platycodonis 5g, Radix Salviae Miltiorrhizae 40g, Rhizoma Chuanxiong 10g, Cortex Magnoliae Officinalis 15g, Bulbus Lilii 20g, Bulbus Fritillariae Thunbergii 15g, Radix Glycyrrhizae 3g and Fructus Jujubae 5g.
Embodiment 4
Treat a Chinese medicine composition for chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 12g, Radix Angelicae Sinensis 25g, Radix Paeoniae Alba 25g, Poria 35g, Rhizoma Atractylodis Macrocephalae 25g, Radix Curcumae 13g, Rhizoma Cyperi 8g, Radix Aucklandiae 13g, Rhizoma Corydalis 15g, Fructus Aurantii 18g, Fructus Amomi 8g, Rhizoma Pinelliae 13g, Pericarpium Citri Reticulatae Viride 8g, Radix Platycodonis 13g, Radix Salviae Miltiorrhizae 25g, Rhizoma Chuanxiong 25g, Cortex Magnoliae Officinalis 8g, Bulbus Lilii 35g, Bulbus Fritillariae Thunbergii 8g, Radix Glycyrrhizae 8g and Fructus Jujubae 10g.
Embodiment 5
Treat a Chinese medicine composition for chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 18g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 35g, Poria 25g, Rhizoma Atractylodis Macrocephalae 35g, Radix Curcumae 8g, Rhizoma Cyperi 13g, Radix Aucklandiae 8g, Rhizoma Corydalis 25g, Fructus Aurantii 12g, Fructus Amomi 13g, Rhizoma Pinelliae 8g, Pericarpium Citri Reticulatae Viride 13g, Radix Platycodonis 8g, Radix Salviae Miltiorrhizae 35g, Rhizoma Chuanxiong 15g, Cortex Magnoliae Officinalis 13g, Bulbus Lilii 25g, Bulbus Fritillariae Thunbergii 13g, Radix Glycyrrhizae 5g and Fructus Jujubae 25g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 6 centimetres of powder, decoct for the first time, adopt intense fire to decoct before at a simmer, after boiling with slow fire boiling 20～30 minutes; Second decocts, and adds water and does not have approximately 6 centimetres of powder, after water boils, decocts 15～20 minutes.Twice decoction extracting juice that removes slag, merges.
The present invention, with the given a kind of Chinese medicine composition for the treatment of chronic gastritis of embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: Chinese medicine composition of the present invention is applied to clinical observation case 50 examples, male 36 examples wherein, female's 24 examples, 20～70 years old age.The shortest person of the course of disease 3 months, elder reaches 2 years, average 0.5 year.
Two, diagnostic criteria:
(1) superficial gastritis
1, asymptomatic or have upper abdominal pain, glutted, belch, decreased food intake etc., occasionally there is upper gastrointestinal hemorrhage;
2, x-ray barium meal examination lacks positive sign;
3, gastric analysis: gastric acid is normal or slightly high;
4. endoscopy is shown in mucosa (reddish tint is main) red and white, and edema, has thick, sticky mucus to adhere to, and can have rotten to the corn and hemorrhage; Mucosa Biopsy is shallow-layer inflammatory cell infiltration, and body of gland is normal;
(2) atrophic gastritis typing standard is as follows:
1, body of stomach gastritis (A type): pathological changes is at body of stomach, diffusivity; Gastric acid lacks as or obviously lowers; Serum gastrin raises; Parietal cell antibodies (PCA) etc. are most positive; IFA can be positive, can merge pernicious anemia;
2, gastric antrum gastritis (Type B): pathological changes, mainly at gastric antrum, can be involved body, kitchen range; Gastric acid is normal or lower slightly; Serum gastrin is normal; BCA, PCA may be positive, can canceration (<4%).Microscopy: can make a definite diagnosis, pathological changes can be confined to body of stomach or gastric antrum portion, also can disperse; Mucosa is greyish white or red and white (Bai Xiangwei master), and pleat attenuates, mucosa attenuation, and under mucosa, blood vessel is shown in thoroughly; Sometimes gland nest hypertrophy, local mucous membrane thickening is graininess and changes (cross and form).Mucosa Biopsy is shown in holostrome cell infiltration, and the large portion of body of gland disappears or disappears (gastratrophia) completely, and generation, severe patient had atypical hyperplasia with intestinal gland metaplasia or gland metaplasia.
Three, usage and dosage: during clinical practice, the component in compositions, consumption are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.One day potion, the about 300ml of twice extracting juice of decocting, minute early, late twice half an hour ante cibum warm taking.Within five days, be a course for the treatment of, period in a medicine avoids eating anything raw or cold, pungent thing.
Four, criterion of therapeutical effect:
(1) cure: clinical cardinal symptom and sign disappear, and chronic inflammatory disease is pass on well slightly;
(2) effective: clinical cardinal symptom disappears, and minor symptom disappears substantially, chronic inflammatory disease takes a turn for the better;
(3) effective: cardinal symptom obviously alleviates, and inflammation alleviates to some extent;
(4) invalid; Cardinal symptom is unchanged, does not also worsen.
Five, therapeutic effect: in this clinical observation case, take medicine 2-10 the course for the treatment of, cure 32 examples, 14 examples that take a turn for the better, 4 examples do not heal.During treatment, there is not toxic and side effects.
Six, model case:
Case 1:
Peaceful certain, female, 52 years old.Main suit when medical: epigastrium repeatedly pain is had a surplus January.Chance labor increases the weight of, and when hungry, very, postprandial pain subtracts pain.With flatulence, belch, occasionally there is dry mouth with bitter taste, swallow sense of obstruction, rare when dry during stool, the tired power, vexed easily dry of body.Through gastroscopy, be diagnosed as: chronic gastritis.Take 1 course for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom disappears substantially, occasionally has loose stool, the tired power of body; Continue to strengthen 2 courses for the treatment of, all symptoms all disappear, and cure.
Case 2:
Finish certain, man, 37 years old.Readme when medical: uncomfortable nearly 2 years of gastral cavilty portion, during beginning, conscious epigastrium has a dull ache, distension and fullness in the abdomen, diet is not good, after gradually increase the weight of to abdominal distention, time have heartburn a, acid regurgitation, the tired power of body.Emaciated physique, lusterless complexion, rare when dry during stool, urine is frequently.Through gastroscopy, be diagnosed as: chronic gastritis.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, after conscious medicine, abdominal distention, gastral cavilty distension slightly alleviate.Continuous take 1 course for the treatment of, abdominal distention, gastral cavilty distension are not obvious; Diet increases, comfortable in stomach after food; Stool once a day, not dry not rare; Without singultus, heartburn, acid regurgitation symptom.Consolidate and take 2 courses for the treatment of again, transference cure, appetite increases, energetic.
Claims (1)
1. a Chinese medicine composition for the treatment of chronic gastritis, is characterized in that: its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 15g, Radix Angelicae Sinensis 20g, Radix Paeoniae Alba 30g, Poria 30g, Rhizoma Atractylodis Macrocephalae 30g, Radix Curcumae 10g, Rhizoma Cyperi 10g, Radix Aucklandiae 10g, Rhizoma Corydalis 20g, Fructus Aurantii 15g, Fructus Amomi 10g, Rhizoma Pinelliae 10g, Pericarpium Citri Reticulatae Viride 10g, Radix Platycodonis 10g, Radix Salviae Miltiorrhizae 30g, Rhizoma Chuanxiong 20g, Cortex Magnoliae Officinalis 10g, Bulbus Lilii 30g, Bulbus Fritillariae Thunbergii 10g, Radix Glycyrrhizae 6g and Fructus Jujubae 15g.
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| CN103599496B (en) * | 2013-12-06 | 2015-06-17 | 陈永庆 | Traditional Chinese medicine for treatment of chronic gastritis |
| CN105031497A (en) * | 2015-08-26 | 2015-11-11 | 南京正宽医药科技有限公司 | Medicinal preparation for treating chronic gastritis |
| CN109289011A (en) * | 2017-07-24 | 2019-02-01 | 徐定清 | A kind of medicine pill for regulating the qi flowing in the channels nourishing the stomach ball of being amusing |
| CN107929631A (en) * | 2017-11-16 | 2018-04-20 | 广西博白县华春福家庭农场 | A kind of pharmaceutical composition for treating chronic gastritis and preparation method thereof |
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| Title |
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| 慢性萎缩性胃炎中医证治规律探讨及临床疗效评价研究;王萍;《中国博士学位论文全文数据库 医药卫生科技辑》;20090115(第1期);第30页第3段-第31页第3行，第34页第8-11,20-23行，第48页倒数第2行-第49页第3行 * |
| 王萍.慢性萎缩性胃炎中医证治规律探讨及临床疗效评价研究.《中国博士学位论文全文数据库 医药卫生科技辑》.2009,(第1期), * |
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