CN104173933A - Traditional Chinese medicine composition for treating depressive disorder - Google Patents

Abstract

The invention relates to a traditional Chinese medicine composition for treating depressive disorder. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of Ziziphora bungeana, 5-20 parts of tribulus terrestris, 10-40 parts of poria with hostwood, 10-30 parts of white paeony root, 5-20 parts of red flower, 10-30 parts of bighead atractylodes rhizome, 10-40 parts of salvia miltiorrhiza, 5-20 parts of pinellia ternate, 5-25 parts of fiveleaf akebia fruit, 5-20 parts of rose, 5-25 parts of schisandra chinensis, 5-20 parts of peach kernel, 10-40 parts of herba epimedii, 5-20 parts of curcuma zedoary, 10-40 parts of rheum officinale, 5-20 parts of cortex lycii radicis, 5-25 parts of fructus psoraleae, 10-40 parts of caulis Spatholobi, 5-20 parts of mangnolia officinalis, 10-40 parts of tuber fleeceflower stem, 5-20 parts of immature bitter orange, 10-30 parts of medlar, 5-20 parts of platycodon grandiflorum, 10-40 parts of Lysimachia christinae Hance, 5-20 parts of pericarpium citri reticulatae viride, 10-30 parts of alpine swertia, 5-20 parts of morinda officinalis, 5-25 parts of semen boitae and 5-15 parts of liquorice. The traditional Chinese medicine composition has the effects of soothing liver-qi stagnation, invigorating spleen and supplementing qi, nourishing the blood and tranquilization and clearing away the heart-fire and relieving restlessness and is obvious in curative effect of treating depressive disorder and reliable in action.

Description

A kind of Chinese medicine composition of Cure of depression

Technical field

The present invention relates to a kind of pharmaceutical product of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition of Cure of depression.

Background technology

Depression claims again melancholia, is a kind of affective state of affective disorders, refers to that the change remarkable and lasting taking mental state (surging or low) is basic clinical, and with corresponding thinking and a dystropic class mental disorder.Clinical manifestation is that mental state is low, retardation of thinking, speech action reduce, and be attended by the somatizations such as appetite depression, hyposexuality, sleep disorder.That heavy patients with depression there will be is pessimistic and worldweary, desperate, oneself crime of self-accusation, hallucination vain hope, inappetence, body weight fall sharply, hypofunction with serious suicidal attempt, even suicide.Data shows, China's depression lifetime prevalence is approximately 7%.Depression has become global main spirits hygienic issues so far, is the harm whole mankind's commonly encountered diseases, frequently-occurring disease, brings huge loss to individual, family and society.At present, western medical treatment depression mainly adopts the medicines such as resist melancholy agent, tranquilizer, sleeping pill, psychosis, but toxic and side effects is large, has certain dependency and expensive.

Depressed card belongs to the melancholia category of the traditional Chinese medical science, and disease is complicated and changeable, and the most common is stagnation of QI due to depression of the liver, syndrome of deficiency of both heart and spleen, how to cause because feelings will is upset, and its pathogenesis is mainly depression of liver-QI, the heart foster, the dysfunction of the spleen in transportation of becoming homeless.

According to theory of Chinese medical science, for the pathogeny of depression, adopt the method for the treatment of of dispersing the stagnated live-QI to relieve the stagnation of QI, invigorating the spleen and benefiting QI, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.

Summary of the invention

There is in order to overcome Cure of depression in prior art the deficiency that drug dependence is strong, side effect is large, the invention provides a kind of prepare easy, cost is low, the Chinese medicine composition of evident in efficacy, the Cure of depression that has no side effect.

The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition of Cure of depression, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Ziziphora bungeana Juz. 10-30 part, Fructus Atriplicis Sibiricae 5-20 part, Poria cum Radix Pini 10-40 part, Radix Paeoniae Alba 10-30 part, Flos Carthami 5-20 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Radix Salviae Miltiorrhizae 10-40 part, Rhizoma Pinelliae 5-20 part, Fructus Akebiae 5-25 part, Flos Rosae Rugosae 5-20 part, Fructus Schisandrae Chinensis 5-25 part, Semen Persicae 5-20 part, Herba Epimedii 10-40 part, Rhizoma Curcumae 5-20 part, Radix Et Rhizoma Rhei 10-40 part, Cortex Lycii 5-20 part, Fructus Psoraleae 5-25 part, Caulis Spatholobi 10-40 part, Cortex Magnoliae Officinalis 5-20 part, Caulis Polygoni Multiflori 10-40 part, Fructus Aurantii Immaturus 5-20 part, Fructus Lycii 10-30 part, Radix Platycodonis 5-20 part, Herba Lysimachiae 10-40 part, Pericarpium Citri Reticulatae Viride 5-20 part, Herba Swertiae heteranthae 10-30 part, Radix Morindae Officinalis 5-20 part, Semen Platycladi 5-25 part, Radix Glycyrrhizae 5-15 part.

The preferred technical solution of the present invention is: a kind of Chinese medicine composition of Cure of depression, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 20 parts of Ziziphora bungeana Juz., 10 parts of Fructus Atriplicis Sibiricaees, 30 parts of Poria cum Radix Pinis, 20 parts of the Radix Paeoniae Albas, 10 parts, Flos Carthami, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Radix Salviae Miltiorrhizaes, 10 parts of the Rhizoma Pinelliaes, 15 parts of Fructus Akebiaes, 10 parts of Flos Rosae Rugosaes, 15 parts of Fructus Schisandrae Chinensis, 10 parts, Semen Persicae, 30 parts of Herba Epimedii, 10 parts of Rhizoma Curcumae, 30 parts of Radix Et Rhizoma Rhei, 12 parts of Cortex Lycii, 15 parts of Fructus Psoraleaes, 30 parts of Caulis Spatholobis, 10 parts of Cortex Magnoliae Officinalis, 30 parts of Caulis Polygoni Multiflori, 10 parts of Fructus Aurantii Immaturuss, 20 parts of Fructus Lyciis, 10 parts of Radix Platycodoniss, 30 parts of Herba Lysimachiaes, 10 parts, Pericarpium Citri Reticulatae Viride, 20 parts of Herba Swertiae heteranthaes, 10 parts of Radix Morindae Officinaliss, 15 parts of Semen Platycladi, 6 parts, Radix Glycyrrhizae.

Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: Ziziphora bungeana Juz. has dispelling wind and heat pathogens, stretches the head clearly, the strong effect of calming the nerves; Fructus Atriplicis Sibiricae has effect of dispersing the stagnated live-QI to relieve the stagnation of QI, dispelling pathogenic wind for improving eyesight; Poria cum Radix Pini has effect of eliminating dampness and diuresis, calming heart and tranquilizing mind; The Radix Paeoniae Alba has effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Flos Carthami has effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis; Radix Salviae Miltiorrhizae has effect of promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; The Rhizoma Pinelliae has drying dampness to eliminate phlegm, effect of stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Fructus Akebiae has effect of liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, relieving restlessness diuresis; Flos Rosae Rugosae has effect of promoting QI circulation for relieving depression, promoting blood flow to regulate menstruation; Fructus Schisandrae Chinensis has effect of astringent or styptic treatment for spontaneous sweating, the supplementing QI for promoting the production of body fluid of convergence, kidney calming; Semen Persicae has effect of blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation; Herba Epimedii has effect of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Rhizoma Curcumae has effect of circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving; Radix Et Rhizoma Rhei has effect of pathogenic fire purging removing food stagnancy, heat-clearing and toxic substances removing, cooling blood for hemostasis, blood stasis dispelling cough-relieving; Cortex Lycii has removing heat from blood effect except steaming, lung heat clearing pathogenic fire reducing; Fructus Psoraleae has effect of reinforcing the kidney and supporting YANG, controlling nocturnal emission with astringent drugs reducing urination, warm spleen antidiarrheal, helping inspiration to relieve asthma; Caulis Spatholobi has to enrich blood invigorates blood circulation, relaxes through effect of dredging collateral; Cortex Magnoliae Officinalis has circulation of qi promoting removing food stagnancy, dampness except effect full, lowering the adverse QI to relieve asthma; Caulis Polygoni Multiflori has effect of tranquilizing by nourishing the heart, dispelling wind and removing obstruction in the collateral; Fructus Aurantii Immaturus has effect of the loose painful abdominal mass of reducing phlegm, dispelling the stagnated QI removing food stagnancy; Fructus Lycii has effect of nourishing the liver and kidney, nourishing the liver to improve visual acuity, strengthening the body resistance, spermatogenesis benefit marrow, enriching yin and nourishing kidney, benefiting vital QI for tranquillizing; Radix Platycodonis has lung qi dispersing and eliminates the phlegm, fosters the spirit of nobility and enrich blood, sharp the five internal organs, mend effect of five kinds of over strain; Herba Lysimachiae has effect of heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, dampness removing jaundice eliminating; Pericarpium Citri Reticulatae Viride has soothing the liver dispelling the stagnated QI, the stagnant effect of removing food stagnancyization; Herba Swertiae heteranthae has effect of suppressing the hyperactive liver sun, tranquilizing by nourishing the heart, nourishing blood for regulating menstruation; Radix Morindae Officinalis has effect of reinforcing the kidney and supporting YANG, bone and muscle strengthening, expelling wind and removing dampness; Semen Platycladi has effect of tranquilizing by nourishing the heart, nourishing YIN and benefiting blood; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, helps using mutual assistant, plays altogether effect of dispersing the stagnated live-QI to relieve the stagnation of QI, invigorating the spleen and benefiting QI, nourishing blood to tranquillize the mind, the relieving restlessness that clears away heart-fire, and the treatment of depression is reached to treating both the principal and secondary aspects of a disease.

The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, and effective percentage reaches 95%, cure rate 70%.

Detailed description of the invention

Below in conjunction with embodiment, the invention will be further described.

Embodiment 1

A Chinese medicine composition for Cure of depression, its raw material of Chinese medicine and weight proportion are: Ziziphora bungeana Juz. 20g, Fructus Atriplicis Sibiricae 10g, Poria cum Radix Pini 30g, Radix Paeoniae Alba 20g, Flos Carthami 10g, Rhizoma Atractylodis Macrocephalae 20g, Radix Salviae Miltiorrhizae 30g, Rhizoma Pinelliae 10g, Fructus Akebiae 15g, Flos Rosae Rugosae 10g, Fructus Schisandrae Chinensis 15g, Semen Persicae 10g, Herba Epimedii 30g, Rhizoma Curcumae 10g, Radix Et Rhizoma Rhei 30g, Cortex Lycii 12g, Fructus Psoraleae 15g, Caulis Spatholobi 30g, Cortex Magnoliae Officinalis 10g, Caulis Polygoni Multiflori 30g, Fructus Aurantii Immaturus 10g, Fructus Lycii 20g, Radix Platycodonis 10g, 30 parts of Herba Lysimachiaes, Pericarpium Citri Reticulatae Viride 10g, Herba Swertiae heteranthae 20g, Radix Morindae Officinalis 10g, Semen Platycladi 15g, Radix Glycyrrhizae 6g.

Embodiment 2

A Chinese medicine composition for Cure of depression, its raw material of Chinese medicine and weight proportion are: Ziziphora bungeana Juz. 10g, Fructus Atriplicis Sibiricae 20g, Poria cum Radix Pini 15g, Radix Paeoniae Alba 30g, Flos Carthami 5g, Rhizoma Atractylodis Macrocephalae 25g, Radix Salviae Miltiorrhizae 10g, Rhizoma Pinelliae 20g, Fructus Akebiae 5g, Flos Rosae Rugosae 15g, Fructus Schisandrae Chinensis 10g, Semen Persicae 20g, Herba Epimedii 15g, Rhizoma Curcumae 5g, Radix Et Rhizoma Rhei 40g, Cortex Lycii 10g, Fructus Psoraleae 25g, Caulis Spatholobi 10g, Cortex Magnoliae Officinalis 20g, Caulis Polygoni Multiflori 10g, Fructus Aurantii Immaturus 15g, Fructus Lycii 30g, Radix Platycodonis 5g, 40 parts of Herba Lysimachiaes, Pericarpium Citri Reticulatae Viride 12g, Herba Swertiae heteranthae 30g, Radix Morindae Officinalis 5g, Semen Platycladi 25g, Radix Glycyrrhizae 12g.

Embodiment 3

A Chinese medicine composition for Cure of depression, its raw material of Chinese medicine and weight proportion are: Ziziphora bungeana Juz. 15g, Fructus Atriplicis Sibiricae 12g, Poria cum Radix Pini 10g, Radix Paeoniae Alba 25g, Flos Carthami 15g, Rhizoma Atractylodis Macrocephalae 10g, Radix Salviae Miltiorrhizae 35g, Rhizoma Pinelliae 12g, Fructus Akebiae 20g, Flos Rosae Rugosae 5g, Fructus Schisandrae Chinensis 25g, Semen Persicae 12g, Herba Epimedii 20g, Rhizoma Curcumae 15g, Radix Et Rhizoma Rhei 10g, Cortex Lycii 20g, Fructus Psoraleae 10g, Caulis Spatholobi 15g, Cortex Magnoliae Officinalis 12g, Caulis Polygoni Multiflori 25g, Fructus Aurantii Immaturus 5g, Fructus Lycii 15g, Radix Platycodonis 20g, 10 parts of Herba Lysimachiaes, Pericarpium Citri Reticulatae Viride 20g, Herba Swertiae heteranthae 10g, Radix Morindae Officinalis 15g, Semen Platycladi 5g, Radix Glycyrrhizae 10g.

Embodiment 4

A Chinese medicine composition for Cure of depression, its raw material of Chinese medicine and weight proportion are: Ziziphora bungeana Juz. 25g, Fructus Atriplicis Sibiricae 5g, Poria cum Radix Pini 35g, Radix Paeoniae Alba 15g, Flos Carthami 12g, Rhizoma Atractylodis Macrocephalae 30g, Radix Salviae Miltiorrhizae 10g, Rhizoma Pinelliae 15g, Fructus Akebiae 10g, Flos Rosae Rugosae 20g, Fructus Schisandrae Chinensis 5g, Semen Persicae 15g, Herba Epimedii 10g, Rhizoma Curcumae 20g, Radix Et Rhizoma Rhei 25g, Cortex Lycii 15g, Fructus Psoraleae 5g, Caulis Spatholobi 25g, Cortex Magnoliae Officinalis 15g, Caulis Polygoni Multiflori 10g, Fructus Aurantii Immaturus 20g, Fructus Lycii 10g, Radix Platycodonis 15g, 25 parts of Herba Lysimachiaes, Pericarpium Citri Reticulatae Viride 5g, Herba Swertiae heteranthae 15g, Radix Morindae Officinalis 20g, Semen Platycladi 10g, Radix Glycyrrhizae 5g.

Embodiment 5

A Chinese medicine composition for Cure of depression, its raw material of Chinese medicine and weight proportion are: Ziziphora bungeana Juz. 30g, Fructus Atriplicis Sibiricae 15g, Poria cum Radix Pini 40g, Radix Paeoniae Alba 10g, Flos Carthami 20g, Rhizoma Atractylodis Macrocephalae 15g, Radix Salviae Miltiorrhizae 40g, Rhizoma Pinelliae 5g, Fructus Akebiae 25g, Flos Rosae Rugosae 12g, Fructus Schisandrae Chinensis 20g, Semen Persicae 5g, Herba Epimedii 40g, Rhizoma Curcumae 12g, Radix Et Rhizoma Rhei 25g, Cortex Lycii 5g, Fructus Psoraleae 20g, Caulis Spatholobi 40g, Cortex Magnoliae Officinalis 5g, Caulis Polygoni Multiflori 40g, Fructus Aurantii Immaturus 12g, Fructus Lycii 25g, Radix Platycodonis 5g, 35 parts of Herba Lysimachiaes, Pericarpium Citri Reticulatae Viride 15g, Herba Swertiae heteranthae 25g, Radix Morindae Officinalis 12g, Semen Platycladi 20g, Radix Glycyrrhizae 15g.

Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 6 centimetres of powder, decoct for the first time, adopt intense fire to decoct before at a simmer, after boiling with slow fire boiling 20～30 minutes; Decoct for the second time, add water and do not have approximately 4 centimetres of powder, after water boils, decoct 15～20 minutes.Decoct extracting juice twice, merge.

The present invention, with the Chinese medicine composition of the given a kind of Cure of depression of embodiment 1, does clinical efficacy and is summarized as follows:

One, general data: this Chinese medicine composition is applied to clinical observation 80 cases, male 33 examples, female's 47 examples, age 20-70 year.

Two, diagnosis basis:

Diagnostic criteria with reference to depression in People's Republic of China's Chinese medicine industry standard " traditional Chinese medical science disease Standardization of diagnosis and curative effect ":

1, melancholy is not smooth, lassitude, feeling of oppression over the chest and distention of hypochondrium; Or anorexia, insomnia and dreamful sleep, irritability the is kind disease such as cry;

2, have disgruntled, worry too much, the feelings history that will is hindered such as grieved, worried;

3, can get rid of organic disease through each systems inspection and lab testing;

4, should differentiate with insane disease, mad disease.

Three, usage and dosage: when clinical practice, potion on the one, the about 400ml of twice extracting juice of decocting, point morning, late twice empty stomach decoction being taken warmly.It within six days, is a course for the treatment of.Avoid cold and uncooked food during the treatment thing of pungent stimulation.

Four, criterion of therapeutical effect:

Depression efficacy assessment standard with reference in People's Republic of China's Chinese medicine industry standard " traditional Chinese medical science disease Standardization of diagnosis and curative effect ":

(1) recovery from illness: transference cure, emotion is normal;

(2) effective: symptom alleviates, and emotion is basicly stable;

(3) invalid: symptom, emotion are all without improving.

Five, therapeutic effect: in this clinical observation case, take medicine 2-5 the course for the treatment of, recovery from illness 56, follows up a case by regular visits to and have no recurrence; Effective 20, invalid 4 examples.During treatment, there is not toxic and side effects.

Six, model case:

Case 1: chapter, man, 32 years old.Because of the smooth mood agitation of work, suffer from depression, often fly into a rage, conscious insobriety, depressed, hypomnesis, once went to too much home's hospitalize, can show effect by Relapse rate, did not feel any better.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, the state of an illness is clearly better; Continue to take 3 courses for the treatment of, symptom, sign disappear completely, and emotion is normal, cure.

Case 2: Jiang, female, 43 years old.Because of family's reason, mood is gloomy, has suffered from depression, often flies into a rage, emotional, two side of body and distending pain of the breast, inappetence, insomnia and dreamful sleep, red tongue with yellow fur, stringy pulse.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, the state of an illness is clearly better, and diet, sleep obviously improve; Continue to take 2 courses for the treatment of, symptom and sign all disappear, and return to one's perfect health.

Claims (2)

1. the Chinese medicine composition of a Cure of depression, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Ziziphora bungeana Juz. 10-30 part, Fructus Atriplicis Sibiricae 5-20 part, Poria cum Radix Pini 10-40 part, Radix Paeoniae Alba 10-30 part, Flos Carthami 5-20 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Radix Salviae Miltiorrhizae 10-40 part, Rhizoma Pinelliae 5-20 part, Fructus Akebiae 5-25 part, Flos Rosae Rugosae 5-20 part, Fructus Schisandrae Chinensis 5-25 part, Semen Persicae 5-20 part, Herba Epimedii 10-40 part, Rhizoma Curcumae 5-20 part, Radix Et Rhizoma Rhei 10-40 part, Cortex Lycii 5-20 part, Fructus Psoraleae 5-25 part, Caulis Spatholobi 10-40 part, Cortex Magnoliae Officinalis 5-20 part, Caulis Polygoni Multiflori 10-40 part, Fructus Aurantii Immaturus 5-20 part, Fructus Lycii 10-30 part, Radix Platycodonis 5-20 part, Herba Lysimachiae 10-40 part, Pericarpium Citri Reticulatae Viride 5-20 part, Herba Swertiae heteranthae 10-30 part, Radix Morindae Officinalis 5-20 part, Semen Platycladi 5-25 part, Radix Glycyrrhizae 5-15 part.

2. a kind of Chinese medicine composition of Cure of depression according to claim 1, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 20 parts of Ziziphora bungeana Juz., 10 parts of Fructus Atriplicis Sibiricaees, 30 parts of Poria cum Radix Pinis, 20 parts of the Radix Paeoniae Albas, 10 parts, Flos Carthami, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Radix Salviae Miltiorrhizaes, 10 parts of the Rhizoma Pinelliaes, 15 parts of Fructus Akebiaes, 10 parts of Flos Rosae Rugosaes, 15 parts of Fructus Schisandrae Chinensis, 10 parts, Semen Persicae, 30 parts of Herba Epimedii, 10 parts of Rhizoma Curcumae, 30 parts of Radix Et Rhizoma Rhei, 12 parts of Cortex Lycii, 15 parts of Fructus Psoraleaes, 30 parts of Caulis Spatholobis, 10 parts of Cortex Magnoliae Officinalis, 30 parts of Caulis Polygoni Multiflori, 10 parts of Fructus Aurantii Immaturuss, 20 parts of Fructus Lyciis, 10 parts of Radix Platycodoniss, 30 parts of Herba Lysimachiaes, 10 parts, Pericarpium Citri Reticulatae Viride, 20 parts of Herba Swertiae heteranthaes, 10 parts of Radix Morindae Officinaliss, 15 parts of Semen Platycladi, 6 parts, Radix Glycyrrhizae.