Background technology
Chronic gastritis is a kind of very common digestive tract disease, is the chronic gastropathy of main pathological change with the non-specific chronic inflammatory disease of gastric mucosa.Pathological changes can be confined to the part of stomach, and whole stomach also can permeate.According to the Histological change of gastric mucosa, can divide three types of shallows, atrophic, plumpness.Gong You symptom is clinically: the vexed bloated pain of epigastrium, belch are frequent, pantothenic acid, loss of appetite, become thin, disease such as diarrhoea.Doctor trained in Western medicine is needing symptomatic treatment aspect the treatment chronic gastritis.For example, available metoclopramide, motilium patient glutted, nauseating, vomiting appear; Dyspeptic patient can take polyzyme tablets, multiple probiotic bacteria etc.; With the patient of bile reflux, in case the bile reflux, also should use in some and the medicine of bile, as the hydrotalcite chewable tablet except using medicine for stomach dynamic (as motilium); Patient to stomach spasm can use Semen daturae tablet, 654-2 with relieving spasm to stop pain; And the patient of acid regurgitation, stomachache is arranged, then can use the PPI preparation and wait to treat.But the patient easily produces dependency to the Western medicine for the treatment of chronic gastritis, and the state of an illness is prone to repeatedly after the drug withdrawal, and the long-term directly effect of Western medicine internal organs, the easily side effect that brings to human body.
Chronic gastritis is modal gastropathy, belongs to sick categories such as Chinese medicine " gastric abscess ", " feeling of fullness ", " acid regurgitation ", " noisy ", " indigestion and loss of appetite ".
The traditional Chinese medical science thinks that chronic gastritis is many because feelings will is unsuccessful for a long time, eating and drinking without temperance, and work and rest is not normal, causes depression of liver-QI, dysfunction of the spleen in transportation, gastral cavilty is become estranged, and with the passing of time middle gas loses empty, thereby causes all symptoms.
According to theory of Chinese medical science, at the pathogeny of chronic gastritis, be the rule for the treatment of with liver-smoothing, qi-regulating, invigorating spleen and reinforcing stomach, dyspepsia and intestinal stasis relieving, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Easily reach the big deficiency of side effect repeatedly in order to overcome after there is drug withdrawal in prior art western medicines in treatment chronic gastritis, the invention provides a kind ofly prepare conveniently, the medicine source is wide, cost is low, the Chinese medicine composition of evident in efficacy, reliable effect, the treatment chronic gastritis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of chronic gastritis is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Bupleuri 10-20 part, Radix Angelicae Sinensis 10-30 part, Radix Paeoniae Alba 20-40 part, Poria 20-40 part, Rhizoma Atractylodis Macrocephalae 20-40 part, Radix Curcumae 5-15 part, Rhizoma Cyperi 5-15 part, Radix Aucklandiae 5-15 part, Rhizoma Corydalis 10-30 part, Fructus Aurantii 10-20 part, Fructus Amomi 5-15 part, Rhizoma Pinelliae 5-15 part, Pericarpium Citri Reticulatae Viride 5-15 part, Radix Platycodonis 5-15 part, Radix Salviae Miltiorrhizae 20-40 part, Rhizoma Chuanxiong 10-30 part, Cortex Magnoliae Officinalis 5-15 part, Bulbus Lilii 20-40 part, Bulbus Fritillariae Thunbergii 5-15 part, Radix Glycyrrhizae 3-10 part and Fructus Jujubae 5-25 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of chronic gastritis is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 15 parts in 15 parts of Radix Bupleuri, 20 parts of Radix Angelicae Sinensis, 30 parts of the Radix Paeoniae Albas, 30 parts of Poria, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Radix Curcumaes, 10 parts of Rhizoma Cyperis, 10 parts of the Radix Aucklandiae, 20 parts of Rhizoma Corydalis, 15 parts of Fructus Aurantiis, 10 parts of Fructus Amomis, 10 parts of the Rhizoma Pinelliaes, 10 parts on Pericarpium Citri Reticulatae Viride, 10 parts of Radix Platycodoniss, 30 parts of Radix Salviae Miltiorrhizaes, 20 parts of Rhizoma Chuanxiongs, 10 parts of Cortex Magnoliae Officinalis, 30 parts of Bulbus Liliies, 10 parts of Bulbus Fritillariae Thunbergiis, 6 parts in Radix Glycyrrhizae and Fructus Jujubae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In the Chinese medicine composition of the present invention: Radix Bupleuri have evacuate bring down a fever, the effect of yang invigorating soothing liver-QI; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation; The Radix Paeoniae Alba has the effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Poria has promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, and mind tranquilizing and the heart calming, anticancer effect relieves internal heat; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis; Radix Curcumae has the effect of regulating qi to disperse stagnation, heart fire-clearing upset-relieving; Rhizoma Cyperi has the effect of the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving; Rhizoma Cyperi has the effect of liver-smoothing, qi-regulating, resolving depression pain relieving; The Radix Aucklandiae has the effect of intestinal stasis relieving in promoting the circulation of QI to relieve pain, the accent; Rhizoma Corydalis has the effect of promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving; Fructus Aurantii has the effect of regulating the flow of QI to ease the stomach, the stagnant relieving distension of row; Fructus Amomi has removing dampness appetizing, warming spleen and stopping diarrha, the antiabortive effect of regulating the flow of vital energy; The Rhizoma Pinelliae has drying dampness to eliminate phlegm, the effect of stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Pericarpium Citri Reticulatae Viride has soothing the liver dispelling the stagnated QI, the stagnant effect of removing food stagnancyization; Radix Platycodonis has lung qi dispersing and eliminates the phlegm, fosters the spirit of nobility and enrich blood, sharp the five internal organs, mend the effect of five kinds of over strain; Radix Salviae Miltiorrhizae has the effect of promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Rhizoma Chuanxiong has the effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Cortex Magnoliae Officinalis has circulation of qi promoting removing food stagnancy, dampness except effect full, lowering the adverse QI to relieve asthma; Bulbus Lilii has the effect of nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization, nourishing essence-blood; Bulbus Fritillariae Thunbergii has removing heat-phlegm, the effect of powder detoxifcation; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription; Fructus Jujubae has the effect of invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays the stagnate effect of relieving distension of liver-smoothing, qi-regulating, invigorating spleen and reinforcing stomach, promoting the circulation of QI to relieve pain, row altogether, chronic gastritis reached the purpose for the treatment of both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, the medicine source is wide, cost is low.It follows the prescription principle of medication of the traditional Chinese medical science, and various component drug adopt the usefulness that is decocted in water for oral dose.Through the clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, toxic and side effects do not occur, total effective rate 92%, cure rate reaches 64%.
The specific embodiment
The present invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind of Chinese medicine composition for the treatment of chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 15g, Radix Angelicae Sinensis 20g, Radix Paeoniae Alba 30g, Poria 30g, Rhizoma Atractylodis Macrocephalae 30g, Radix Curcumae 10g, Rhizoma Cyperi 10g, Radix Aucklandiae 10g, Rhizoma Corydalis 20g, Fructus Aurantii 15g, Fructus Amomi 10g, Rhizoma Pinelliae 10g, Pericarpium Citri Reticulatae Viride 10g, Radix Platycodonis 10g, Radix Salviae Miltiorrhizae 30g, Rhizoma Chuanxiong 20g, Cortex Magnoliae Officinalis 10g, Bulbus Lilii 30g, Bulbus Fritillariae Thunbergii 10g, Radix Glycyrrhizae 6g and Fructus Jujubae 15g.
Embodiment 2
A kind of Chinese medicine composition for the treatment of chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 10g, Radix Angelicae Sinensis 30g, Radix Paeoniae Alba 20g, Poria 40g, Rhizoma Atractylodis Macrocephalae 20g, Radix Curcumae 15g, Rhizoma Cyperi 5g, Radix Aucklandiae 15g, Rhizoma Corydalis 10g, Fructus Aurantii 20g, Fructus Amomi 5g, Rhizoma Pinelliae 15g, Pericarpium Citri Reticulatae Viride 5g, Radix Platycodonis 15g, Radix Salviae Miltiorrhizae 20g, Rhizoma Chuanxiong 30g, Cortex Magnoliae Officinalis 5g, Bulbus Lilii 40g, Bulbus Fritillariae Thunbergii 5g, Radix Glycyrrhizae 10g and Fructus Jujubae 20g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 20g, Radix Angelicae Sinensis 10g, Radix Paeoniae Alba 40g, Poria 20g, Rhizoma Atractylodis Macrocephalae 40g, Radix Curcumae 5, Rhizoma Cyperi 15g, Radix Aucklandiae 5g, Rhizoma Corydalis 30g, Fructus Aurantii 10g, Fructus Amomi 15g, Rhizoma Pinelliae 5g, Pericarpium Citri Reticulatae Viride 15g, Radix Platycodonis 5g, Radix Salviae Miltiorrhizae 40g, Rhizoma Chuanxiong 10g, Cortex Magnoliae Officinalis 15g, Bulbus Lilii 20g, Bulbus Fritillariae Thunbergii 15g, Radix Glycyrrhizae 3g and Fructus Jujubae 5g.
Embodiment 4
A kind of Chinese medicine composition for the treatment of chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 12g, Radix Angelicae Sinensis 25g, Radix Paeoniae Alba 25g, Poria 35g, Rhizoma Atractylodis Macrocephalae 25g, Radix Curcumae 13g, Rhizoma Cyperi 8g, Radix Aucklandiae 13g, Rhizoma Corydalis 15g, Fructus Aurantii 18g, Fructus Amomi 8g, Rhizoma Pinelliae 13g, Pericarpium Citri Reticulatae Viride 8g, Radix Platycodonis 13g, Radix Salviae Miltiorrhizae 25g, Rhizoma Chuanxiong 25g, Cortex Magnoliae Officinalis 8g, Bulbus Lilii 35g, Bulbus Fritillariae Thunbergii 8g, Radix Glycyrrhizae 8g and Fructus Jujubae 10g.
Embodiment 5
A kind of Chinese medicine composition for the treatment of chronic gastritis, its raw material of Chinese medicine and weight proportion are: Radix Bupleuri 18g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 35g, Poria 25g, Rhizoma Atractylodis Macrocephalae 35g, Radix Curcumae 8g, Rhizoma Cyperi 13g, Radix Aucklandiae 8g, Rhizoma Corydalis 25g, Fructus Aurantii 12g, Fructus Amomi 13g, Rhizoma Pinelliae 8g, Pericarpium Citri Reticulatae Viride 13g, Radix Platycodonis 8g, Radix Salviae Miltiorrhizae 35g, Rhizoma Chuanxiong 15g, Cortex Magnoliae Officinalis 13g, Bulbus Lilii 25g, Bulbus Fritillariae Thunbergii 13g, Radix Glycyrrhizae 5g and Fructus Jujubae 25g.
Chinese medicine composition in embodiment of the invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 15~20 minutes, add water again and do not have about 6 centimetres of powder, carry out the decoction first time, at a simmer the preceding intense fire that adopts decocts, and slow fire boiling 20~30 minutes are used in the back of boiling; Second decocts, and adds water and does not have about 6 centimetres of powder, decocts 15~20 minutes after water boils.Twice decoction extracting juice that removes slag merges.
The present invention does clinical efficacy and is summarized as follows with the given a kind of Chinese medicine composition for the treatment of chronic gastritis of embodiment 1:
One, general data: Chinese medicine composition of the present invention is applied to clinical observation case 50 examples, male 36 examples wherein, women 24 examples, 20~70 years old age.The shortest person of the course of disease 3 months, elder reaches 2 years, average 0.5 year.
Two, diagnostic criteria:
(1) superficial gastritis
1, asymptomatic or upper abdominal pain, glutted, belch, decreased food intake etc. are arranged, idol has upper gastrointestinal hemorrhage;
2, x-ray barium meal examination lacks positive sign;
3, gastric analysis: gastric acid is normal or high slightly;
4. endoscopy is seen mucosa (reddish tint is main) red and white, and edema has thick, sticky mucus to adhere to, and can have rotten to the corn and hemorrhage; The mucosa biopsy is the shallow-layer inflammatory cell infiltration, and body of gland is normal;
(2) atrophic gastritis typing standard is as follows:
1, body of stomach gastritis (A type): pathological changes is at body of stomach, diffusivity; Gastric acid lacks as or obviously lowers; Serum gastrin raises; Parietal cell antibodies (PCA) etc. are most positive; IFA can be positive, can merge pernicious anemia;
2, gastric antrum gastritis (Type B): pathological changes can be involved body, kitchen range mainly at gastric antrum; Gastric acid is normal or lower slightly; Serum gastrin is normal; BCA, PCA may be positive, but canceration (<4%).Microscopy: can make a definite diagnosis, pathological changes can be confined to body of stomach or gastric antrum portion, but also disperse; Mucosa is greyish white or red and white (Bai Xiangwei master), and pleat attenuates, the mucosa attenuation, and blood vessel is seen thoroughly under the mucosa; Sometimes gland nest hypertrophy, local mucous membrane thickening are graininess and change (cross and form).The holostrome cell infiltration is seen in the mucosa biopsy, and big of body of gland disappears or complete obiteration (gastratrophia), and generation, severe patient had atypical hyperplasia with intestinal gland metaplasia or pylorus glandular metaplasia.
Three, usage and dosage: during clinical practice, the component in the compositions, consumption are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.One day potion, the about 300ml of twice extracting juice of decocting, divide early, late twice half an hour ante cibum warm taking.Five days is a course for the treatment of, and period in a medicine avoids eating anything raw or cold, pungent thing.
Four, criterion of therapeutical effect:
(1) cure: clinical cardinal symptom and sign disappear, and chronic inflammatory disease is pass on well slightly;
(2) produce effects: clinical cardinal symptom disappears, and minor symptom disappears substantially, and chronic inflammatory disease takes a turn for the better;
(3) effective: cardinal symptom obviously alleviates, and inflammation alleviates to some extent;
(4) invalid; The cardinal symptom no change does not worsen yet.
Five, therapeutic effect: in this clinical observation case, take medicine 2-10 the course for the treatment of, cure 32 examples, 14 examples that take a turn for the better, 4 examples do not heal.Toxic and side effects does not take place during the treatment.
Six, model case:
Case 1:
Peaceful certain, woman, 52 years old.Main suit during prescription on individual diagnosis: epigastrium pain is repeatedly had a surplus January.Chance labor increases the weight of, and bitterly very, postprandial pain subtracts when hungry.With flatulence, belch, idol has dry mouth with bitter taste, swallows sense of obstruction, and is rare when doing during stool, the tired power, vexed easily dry of body.Be diagnosed as through gastroscopy: chronic gastritis.Take 1 course for the treatment of of medicament of Chinese medicine composition preparation of the present invention, symptom disappears substantially, and idol has the loose stool, the tired power of body; Continue to strengthen 2 courses for the treatment of, all symptoms all disappear, and cure.
Case 2:
Finish certain, man, 37 years old.Readme during prescription on individual diagnosis: uncomfortable nearly 2 years of gastral cavilty portion, conscious epigastrium has a dull ache during beginning, distension and fullness in the abdomen, diet are not good, after gradually increase the weight of to abdominal distention, the time heartburn, acid regurgitation, the tired power of body arranged.Emaciated physique, lusterless complexion, rare when doing during stool, urine is frequently.Be diagnosed as through gastroscopy: chronic gastritis.Take 2 courses for the treatment of of medicament of Chinese medicine composition preparation of the present invention, abdominal distention, gastral cavilty distension alleviate slightly behind the conscious medicine.1 course for the treatment of of continuous clothes, abdominal distention, gastral cavilty distension are not obvious; Diet increases, and is comfortable in the stomach of food back; Stool does not do not rare once a day; No singultus, heartburn, acid regurgitation symptom.Consolidate again and take 2 courses for the treatment of, transference cure, appetite increases, and is energetic.