CN104413019B - A kind of composition pesticide of fluorine-containing ether bacterium amide - Google Patents
A kind of composition pesticide of fluorine-containing ether bacterium amide Download PDFInfo
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- CN104413019B CN104413019B CN201310415089.3A CN201310415089A CN104413019B CN 104413019 B CN104413019 B CN 104413019B CN 201310415089 A CN201310415089 A CN 201310415089A CN 104413019 B CN104413019 B CN 104413019B
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Abstract
The invention discloses a kind of composition pesticide of fluorine-containing ether bacterium amide, active ingredient is active components A and active constituent B, and active components A is selected from fluorine ether bacterium amide, and active constituent B is selected from any one following compound：Propineb, Carbatene, Mancozeb, zineb or zinc thiazole, and active components A and the weight ratio of active constituent B are 1：80~80：1.The present composition has synergistic effect to the multiple diseases for endangering agricultural production, reduces pesticide usage amount, reduces residual quantity of the pesticide on crop, alleviate environmental pollution, to safety of human and livestock, Environmental compatibility is good, and disease is not likely to produce drug resistance.
Description
Technical field
The invention belongs to technical field of pesticide, it is related to a kind of composition pesticide of fluorine-containing ether bacterium amide on corps diseases
Application.
Background technology
Fluorine ether bacterium amide (LH-2010A) selective fungicide fluopicolide more similar than structure has wider array of fungicidal spectrum.
Fluorine ether bacterium amide is to the bacteriostatic activity highest of cotton standing dead rhizoctonia and botrytis cinerea, to Phytophthora capsici and potato late blight
Germ has higher antibacterial work, and fluorine ether bacterium amide is apparent to cotton standing dead rhizoctonia bacteriostasis, can significantly inhibit its sclerotium
Generation and mycelium morphology factor, make mycelia branch increase, shorten, is thicker；Fluorine ether bacterium amide has various plants pathogen higher
Bacteriostatic activity, and can obviously inhibit the multinomial physical signs of cotton standing dead rhizoctonia.
Propineb, Carbatene, Mancozeb, zineb or zinc thiazole belong to common fungicide, are widely used in farming
In the disease of object.
However, in the real process of agricultural production, the problem of controlling disease most easily produces is the production of disease drug resistance
It is raw.Different cultivars ingredient is compounded, and is to prevent the very common method of resistance disease.Heterogeneity is compounded, according to reality
Application effect, to judge that certain compounding is synergy, adduction or antagonism.In most cases, the compounding effect of sterilization
All it is additive effect, really has the compounding of synergistic effect seldom, especially synergistic effect is clearly, synergy ratio is very high answers
With just less.It studies, is found fluorine ether bacterium amide and Propineb, Carbatene, Mancozeb, zineb or thiophene by inventor
Good synergistic effect can be generated after azoles zinc compounding, and about fluorine ether bacterium amide and Propineb, Carbatene, Mancozeb, generation
The relevant report of gloomy zinc or zinc thiazole compounding not yet discloses.
Invention content
There is synergistic function, the fluorine-containing ether bacterium acyl that use cost is low, preventive effect is good the purpose of the present invention is to propose to a kind of
The composition pesticide of amine.
The composition pesticide of fluorine-containing ether bacterium amide proposed by the present invention contains active components A and active constituent B, and activity is divided into
A and active constituent B weight ratios are 1: 80~80: 1, and the active components A is selected from fluorine ether bacterium amide, and active constituent B selects third gloomy
One of zinc, Carbatene, Mancozeb, zineb or zinc thiazole are planted, and active components A is with the preferred weight ratios of active constituent B
1：60~60：1；More preferably the weight ratio of fluorine ether bacterium amide and Propineb is 5：1~1：35, fluorine ether bacterium amide and Carbatene
Weight ratio is 20：1~1：20, the weight ratio of fluorine ether bacterium amide and Mancozeb is 5：1~1：35, fluorine ether bacterium amide and zineb
Weight ratio be 5：1~1：35, the weight ratio of fluorine ether bacterium amide and zinc thiazole is 15：1~1：25；Most preferably fluorine ether bacterium amide
Weight ratio with Propineb is 1：4~1：24, the weight ratio of fluorine ether bacterium amide and Carbatene is 9：1~1：9, fluorine ether bacterium amide and
The weight ratio of Mancozeb is 1：4~1：24, the weight ratio of fluorine ether bacterium amide and zineb is 1：4~1：24, fluorine ether bacterium amide
Weight ratio with zinc thiazole is 4：1~1：14.
The composition pesticide of fluorine-containing ether bacterium amide proposed by the present invention is used to prevent the purposes of disease on crops, described
Crops include cereal crops, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit crop,
Have a liking for crop, root crop, oil crops, flower crop, medicinal crop, crop, green manure pasture crop；The disease
Evil includes epidemic disease, anthracnose, downy mildew, spot defoliation, root rot, samping off, seedling rot, brown spot, black rot, black star
Disease, blossom rot, ring spot, mildew disease, rust, white rot, anthrachose of grape, Leucoplakia, spot blight, Phomopisis vexans, black spot, continuous epidemic disease
Disease, soft rot, balck shank, stem wilt, damping-off, canker or cecospora spot.
Active components A, the weight ratio of active constituent B are 1：80~80：1.The weight hundred of active component in usual composition
Divide content for the 0.5%~90% of total weight, preferably 5%~80%.According to different preparation types, active component content
Range is different.In general, liquid preparation contains by weight 1%~70% active material, preferably 5%~50%；
Solid pharmaceutical preparation contains by weight 5%~80% active material, preferably 10%~80%.
The present invention bactericidal composition at least contain a kind of surfactant, in favor of application when active component in water
Dispersion.Surface-active contents are the 5%~30% of total formulation weight, and surplus is solid or liquid diluent.
The bactericidal composition of the present invention can used before through dilution or directly by user.Its preparation can be by usual
Processing method known in those skilled in the art prepare, i.e., after active material being mixed with liquid flux or solid carrier,
Add one kind in surfactant such as dispersant, stabilizer, wetting agent, binder, antifoaming agent, disintegrant, antifreeze
Or it is several.
The bactericidal composition of the present invention, can be processed into acceptable dosage form in any sterilization, wherein more preferably on demand
Dosage form be that wettable powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent or micro-capsule are outstanding
Floating-suspending agent, can also be made granule, seed coat agent, suspension seed-coating agent, ultra low volume liquids, seed treatment emulsion, work as activity
Its dosage form is wettable powder and water dispersible granules when ingredient B is Propineb.
Composition includes following constituent content when wettable powder is made：Active components A 0.1%~80%, active constituent
B0.1%~80%, dispersant 2%~10%, wetting agent 2%~10%, filler surplus.
Composition includes following constituent content when water dispersible granules are made：Active components A 0.1%~80%, active constituent
B0.1%~80%, dispersant 3%~12%, wetting agent 1%~8%, disintegrant 1%~10%, binder 0~8%, filler
Surplus.
Composition includes following constituent content when suspending agent is made：Active components A 0.1%~50%, active constituent
B0.1%~50%, dispersant 2%~10%, wetting agent 2%~10%, antifoaming agent 0.01%~2%, thickener 0~2%,
Antifreeze 0~8%, deionized water add to 100%.
Composition includes following constituent content when suspension emulsion is made：Active components A 0.1%~50%, active constituent
B0.1%~50%, dispersant 2%~10%, antifoaming agent 0.01%~2%, solvent 1%~15%, thickener 0~2%, breast
Agent 2%~12%, antifreeze 0~8%, deionized water add to 100%.
Composition includes following constituent content when aqueous emulsion is made：Active components A 0.5%~50%, active constituent
B0.5%~50%, solvent 1%~30%, emulsifier 1%~15%, antifreeze 0~8%, thickener 0~2%, antifoaming agent
0.01%~2%, deionized water supplies surplus.
Composition includes following constituent content when microemulsion is made：Active components A 0.5%~50%, active constituent
B0.5%~50%, emulsifier 3%~25%, antifreeze 0~8%, antifoaming agent 0.01%~2%, is gone solvent 1%~30%
Ionized water supplies surplus.
Composition includes following constituent content when microcapsule suspending agent is made：Active components A 0.5%~50%, active constituent
B0.5%~50%, macromolecule cyst material 2%~10%, dispersant 1%~10%, organic solvent 1%~10%, emulsifier
1%~7%, antifoaming agent 0.01%~2%, pH adjusting agent 0.01%~5%, deionized water add to 100%.
Composition includes following constituent content when microcapsule suspension-suspendinagent agent is made：Active components A 0.5%~50%, activity
It is ingredient B0.5%~50%, macromolecule cyst material 2%~10%, dispersant 1%~12%, wetting agent 1%~8%, organic
Solvent 1%~15%, emulsifier 1%~6%, antifoaming agent 0.01%~2%, thickener 0~2%, pH adjusting agent 0.01%~
5%, deionized water adds to 100%；
The wettable powder the key technical indexes of the present invention：
The water dispersible granules the key technical indexes of the present invention：
The suspending agent the key technical indexes of the present invention：
The suspension emulsion the key technical indexes of the present invention：
The aqueous emulsion the key technical indexes of the present invention：
The microemulsion the key technical indexes of the present invention：
The microcapsule suspending agent the key technical indexes of the present invention：
The one suspending agent the key technical indexes of microcapsule suspension of the present invention：
The advantage of the invention is that：
(1) fluorine ether bacterium amide has apparent with after Propineb, Carbatene, Mancozeb, zineb or zinc thiazole compounding
Synergy and lasting effect；(2) to cereal crops, legume crop, fibre crops, sugar crop, melon crop, fruits crop,
Dry fruit crop, hobby crop, root crop, oil crops, flower crop, medicinal crop, crop, green manure herbage make
Disease on object has greater activity；(3) reduce pesticide usage amount, reduce residual quantity of the pesticide on crop, alleviate
Environmental pollution；(4) to safety of human and livestock, Environmental compatibility is good；And preparation adhesion strength enhances, resistance of rainwater washing against.
Specific implementation mode
With reference to embodiment to further instruction of the present invention, the percentage in embodiment is weight percentage, but
The present invention is not limited thereto.
Application Example one
1~16 wettable powder of embodiment
Fluorine ether bacterium amide, active constituent B, dispersant, wetting agent, filler are uniformly mixed in mixed cylinder, through air-flow powder
Broken machine remixes uniformly after crushing, you can wettable powder product of the present invention is made, is specifically shown in Table 1.
1 embodiment 1~16 of table is respectively segmented and parts by weight
17~32 water dispersible granules of embodiment
Fluorine ether bacterium amide, active constituent B, dispersant, wetting agent, disintegrant, filler etc. are obtained through air-flow crushing together
The grain size needed adds other auxiliary agents such as binder (can add can be not added with), obtains granulation materials.Item is quantified into feeding fluidisation
In bed granulating drier after granulation and drying, you can water dispersible granules product of the present invention is made, is specifically shown in Table 2.
2 embodiment of table, 17~32 each component and parts by weight
Propineb, Carbatene, Mancozeb, zineb or zinc thiazole in table 1-2 are exchanged, novel formulation can be made.
33~48 suspending agent of embodiment
By dispersant, wetting agent, antifoaming agent, thickener (can add can be not added with), antifreeze (can add can be not added with), by high speed
Shear-mixed is uniform, fluorine ether bacterium amide, active constituent B is added, ball milling 2~3 hours, make diameter of particle all exist in the ball mill
5 μm hereinafter, surplus is supplied with deionized water, you can suspending agent product of the present invention is made, is specifically shown in Table 3.
3 embodiment of table, 33~48 each component and parts by weight
49~56 suspension emulsion of embodiment
Dispersant, antifoaming agent, thickener (can add can be not added with), antifreeze (can add can be not added with) are mixed by high speed shear
Uniformly, fluorine ether bacterium amide is added, in the ball mill ball milling 2~3 hours, makes diameter of particle all at 5 μm hereinafter, fluorine ether bacterium is made
Then active constituent B, solvent, emulsifier and various auxiliary agents are directly emulsified with high speed agitator and arrive suspending agent by amide suspending agents
In, surplus is supplied with deionized water, and suspension emulsion product of the present invention is made, is specifically shown in Table 4.
4 embodiment of table, 49~56 each component and parts by weight
57~64 aqueous emulsion of embodiment
Fluorine ether bacterium amide, active constituent B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase；By deionization
Water, antifreeze (can add can be not added with), thickener (can add can be not added with), antifoaming agent mix, at uniform water phase.In high-speed stirring
It mixes down, oil phase is added in water phase, surplus is supplied with deionized water；Aqueous emulsion product of the present invention is can be prepared by, is specifically shown in
Table 5.
5 embodiment of table, 57~64 each component and parts by weight
Carbatene, Mancozeb, zineb or zinc thiazole in table 3-5 are exchanged, novel formulation can be made.
65~67 microemulsion of embodiment
Fluorine ether bacterium amide, active constituent B, solvent, emulsifier, antifreeze (can add can be not added with), antifoaming agent are sufficiently mixed
At the oil phase of homogeneous transparent, it is slowly added into deionized water under stiring, forms WO emulsion, then agitated heating, makes
Rapid phase inversion at oil-in-water type, be cooled to room temperature and make up to balance, through filtering, surplus supplied with deionized water；It can be prepared by
Microemulsion product of the present invention, is specifically shown in Table 6.
6 embodiment 65~67 of table is respectively segmented and parts by weight
Embodiment 68,69 microcapsule suspending agents
Fluorine ether bacterium amide, active constituent B, macromolecule cyst material, solvent are mixed, makes to be dissolved into homogeneous oil phase, cut
Under tangent condition, by oil phase be added to containing emulsifier, pH adjusting agent, dispersant aqueous phase solution in, surplus is mended with deionized water
Foot, two kinds of materials react in oil-water interfaces, form high score ascus wall, and it is outstanding that the well dispersed micro-capsule of the present composition is made
Floating agent product.Specifically it is shown in Table 7.
7 embodiment 68 of table, 69 each components and parts by weight
Embodiment 70,71 microcapsule suspension-suspendinagent agents
Active constituent B, macromolecule cyst material, solvent are mixed, make to be dissolved into homogeneous oil phase, by oil phase in shearing condition
Under be added to containing emulsifier, pH adjusting agent aqueous phase solution in, well dispersed microcapsule suspending agent is made.By dispersant, wet
Profit agent, antifoaming agent, thickener (can add can be not added with) are uniformly mixed by high speed shear, fluorine ether bacterium amide are added, in the ball mill
Ball milling 2~3 hours makes diameter of particle all at 5 μm hereinafter, suspending agent is made, suspending agent is then added to microcapsules and is suspended
In the aqueous phase solution of agent, deionized water supplies surplus, and the well dispersed microcapsule suspension-suspendinagent agent production of the present composition is made
Product are specifically shown in Table 8.
8 embodiment 70 of table, 71 each components and parts by weight
Active constituent B is Carbatene, Mancozeb, zineb or zinc thiazole in table 6-8.
The embodiment of the present invention is the method being combined using Toxicity Determination and field trial.First pass through indoor virulence survey
It is fixed, define the synergy ratio (SR) after two kinds of medicaments compound by a certain percentage, SR<0.5 is antagonism, and 0.5≤SR≤1.5 are
Summation action, SR>1.5 be synergistic effect, on this basis, then carries out field trial.
Test method：After prerun determines the effective inhibition concentration range of each medicament, medicament sets 5 respectively by active constituent content
A dosage processing, if clear water compares.Reference《Farm-chemical indoor determination test rule fungicide》It carries out, speed is grown using mycelia
Rate method measures virulence of the medicament to crop germ.Colony diameter is measured with crossing method after 72h, calculates the net growth of each processing
Amount, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter 1
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) is converted into logarithm (x), with minimum
Square law acquires virulence regression equation (y=a+bx), and thus calculates the EC of each medicament50Value.Simultaneously according to Wad1ey method meters
Calculate two medicament different ratio synergy ratios (SR), SR<0.5 is antagonism, and 0.5≤SR≤1.5 are summation action, SR>
1.5 be synergistic effect.Calculation formula is as follows：
Wherein：A, b is respectively active components A and active constituent B ratio shared in combination；
A is fluorine ether bacterium amide；
B is selected from one of Propineb, Carbatene, Mancozeb, zineb or zinc thiazole kind.
Application Example two：
For trying disease：Cucumber downy mildew
Test medicine is provided by applicant.
Experimental design：Having for fluorine ether bacterium amide and Propineb active compound and the two different ratio mixture is determined by pilot study
Imitate inhibition concentration range.
Toxicity test result
9 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to cucumber downy mildew with Propineb
As shown in Table 9, fluorine ether bacterium amide is matched with Propineb 1：80~80：To the synergy ratio of cucumber downy mildew when 1
SR is all higher than 1.5, illustrates the two 1：Mixture shows synergistic effect in 80~80: 1 range, when fluorine ether bacterium amide and third gloomy
The proportioning of zinc is 5：1~1：When 35, synergistic effect is more prominent, and synergy ratio is 2.35 or more；When fluorine ether bacterium amide and third
The proportioning of gloomy zinc is 1：4~1：When 24, synergistic effect is more prominent, and synergy ratio is 2.40 or more.It tests and sends out through applicant
The optimum ratio of existing fluorine ether bacterium amide and Propineb is 5：1、4：1、3：1、2：1、1：1、1：2、1：3、1：4、1：5、1：6、1∶7、1
∶8、1∶9、1∶10、1∶11、1∶12、1∶13、1∶14、1∶15、1：16、1：17、1：18、1：19、1：20、1：21、1：22、1：23、
1：24、1：25、1：26、1：27、1：28、1：29、1：30、1：31、1：32、1：33、1：34、1：35, especially when fluorine ether bacterium acyl
Amine is 1 with Propineb weight ratio：Synergy ratio is maximum when 14, and synergistic effect is the most apparent.
Application Example three：
For trying disease：Downy mildew of garpe
Test medicine is provided by applicant.
Experimental design：Having for fluorine ether bacterium amide and Carbatene active compound and the two different ratio mixture is determined by pilot study
Imitate inhibition concentration range.
Toxicity test result
10 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to downy mildew of garpe with Carbatene
As shown in Table 10, fluorine ether bacterium amide is matched with Carbatene 1：80~80：To the synergy ratio of downy mildew of garpe when 1
SR is all higher than 1.5, illustrates the two 1：80~80：Mixture shows synergistic effect in 1 range, as fluorine ether bacterium amide and Dai Sen
The proportioning of connection is 20：1~1：When 20, synergistic effect is more prominent, and synergy ratio is 2.25 or more；When fluorine ether bacterium amide and generation
Gloomy proportioning is 1：9~1：When 9, synergistic effect is more prominent, and synergy ratio is 2.30 or more.It tests and finds through applicant
The optimum ratio of fluorine ether bacterium amide and Carbatene is 20: 1,19：1、18：1、17：1、16：1、15：1、14：1、13：1、12：1、
11：1、10：1、9：1、8：1、7：1、6：1、5：1、4∶1、3：1、2：1、1：1、1：2、1：3、1：4、1∶5、1：6、1：7、1：8、1∶
9、1∶10、1：11、1∶12、1：13、1∶14、1：15、1∶16、1：17,1: 18,1: 19,1: 20, especially when fluorine ether bacterium amide with
Carbatene weight ratio is 1：Synergy ratio is maximum when 1, and synergistic effect is the most apparent.
Application Example four：
For trying disease：Apple peels and cores
Test medicine is provided by applicant.
Experimental design：Fluorine ether bacterium amide and Mancozeb active compound and the two different ratio mixture are determined by pilot study
Effective inhibition concentration range.
Toxicity test result
11 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to apple peels and cores with Mancozeb
As shown in Table 11, fluorine ether bacterium amide is matched with Mancozeb 1：80~80：To apple peels and cores when 1
Synergy ratio SR is all higher than 1.5, illustrates the two 1：80~80：Mixture shows synergistic effect in 1 range, when fluorine ether bacterium acyl
The proportioning of amine and Mancozeb is 5：1~1：When 35, synergistic effect is more prominent, and synergy ratio is 2.30 or more；When fluorine ether
The proportioning of bacterium amide and Mancozeb is 1：4~1：When 24, synergistic effect is more prominent, and synergy ratio is 2.40 or more.Through
Applicant, which tests, finds that the optimum ratio of fluorine ether bacterium amide and Mancozeb is 5：1、4：1、3：1、2∶1、1∶1、1：2、1：3、1∶
4、1∶5、1：6、1：7、1∶8、1：9、1：10、1∶11、1：12、1：13、1：14、1：15、1：16、1：17、1∶18、1：19、1：20、
1：21、1：22、1：23、1：24、1：25、1：26、1：27、1：28、1：29、1：30、1：31、1：32、1：33、1：34、1：35, especially
It is when fluorine ether bacterium amide and Mancozeb weight ratio are 1：Synergy ratio is maximum when 14, and synergistic effect is the most apparent.
Application Example five：
For trying disease：Tomato blight
Test medicine is provided by applicant.
Experimental design：Having for fluorine ether bacterium amide and zineb active compound and the two different ratio mixture is determined by pilot study
Imitate inhibition concentration range.
Toxicity test result
12 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to tomato blight with zineb
As shown in Table 12, fluorine ether bacterium amide is matched with zineb 1: 80~80：To the synergy ratio SR of tomato blight when 1
1.5 are all higher than, illustrates the two 1：80~80：Mixture shows synergistic effect in 1 range, when fluorine ether bacterium amide and zineb
Proportioning 5：When 1~1: 35, synergistic effect is more prominent, and synergy ratio is 2.30 or more；As fluorine ether bacterium amide and Dai Sen
The proportioning of zinc is 1：4~1：When 24, synergistic effect is more prominent, and synergy ratio is 2.45 or more.It tests and finds through applicant
The optimum ratio of fluorine ether bacterium amide and zineb is 5：1、4：1、3：1、2：1、1：1、1：2、1：3、1：4、1：5、1：6、1：7、1：
8、1：9、1：10、1：11、1：12、1：13、1：14、1：15、1∶16、1：17、1：18、1：19、1：20、1：21、1：22、1：23、
1：24、1：25、1：26、1：27、1：28、1：29、1：30、1：31、1：32、1：33、1：34、1：35, especially when fluorine ether bacterium acyl
Amine is 1 with zineb weight ratio：Synergy ratio is maximum when 16, and synergistic effect is the most apparent.
Application Example six：
For trying disease：Mandarin tree canker
Test medicine is provided by applicant.
Experimental design：Having for fluorine ether bacterium amide and zinc thiazole active compound and the two different ratio mixture is determined by pilot study
Imitate inhibition concentration range.
Toxicity test result
13 fluorine ether bacterium amide of table compounds the toxicity test analysis of results table to mandarin tree canker with zinc thiazole
As shown in Table 13, fluorine ether bacterium amide is matched with zinc thiazole 1：80~80：To the synergic ratio of mandarin tree canker when 1
Value SR is all higher than 1.5, illustrates the two 1：Mixture shows synergistic effect in 80~80: 1 range, when fluorine ether bacterium amide and thiophene
The proportioning of azoles zinc is 15：1~1：When 25, synergistic effect is more prominent, and synergy ratio is 2.30 or more；When fluorine ether bacterium amide with
The proportioning of zinc thiazole is 4: 1~1：When 14, synergistic effect is more prominent, and synergy ratio is 2.45 or more.It is tested through applicant
It was found that the optimum ratio of fluorine ether bacterium amide and zinc thiazole is 15：1、14：1、13：1、12：1、11：1、10：1、9：1、8：1、7：1、
6：1、5：1、4：1、3：1、2：1、1：1、1：2、1：3、1：4、1∶5、1∶6、1∶7、1∶8、1∶9、1∶10、1∶11、1∶12、1∶13、
1：14、1：15、1∶16、1：17、1∶18、1：19、1：20、1：21、1：22、1：23、1：24、1：25, especially when fluorine ether bacterium acyl
Amine is 1 with zinc thiazole weight ratio：Synergy ratio is maximum when 3, and synergistic effect is the most apparent.
It is found through experiment that：To the epidemic disease in various crop, anthracnose, downy mildew after fluorine ether bacterium amide and active constituent B compoundings
Disease, spot defoliation, root rot, samping off, seedling rot, brown spot, black rot, scab, blossom rot, ring spot, mildew disease,
Rust, anthrachose of grape, Leucoplakia, spot blight, Phomopisis vexans, black spot, cotton disease, soft rot, balck shank, stem wilt, is stood white rot
The prevention of blight, canker or cecospora spot has apparent synergistic effect, synergy ratio SR to be all higher than 1.5.
Effect experiment part：Test medicine is researched and developed by applicant, is provided, 50% fluorine ether bacterium amide wettable powder of comparison medicament
In agent (matching in vain), 70% Wettable propineb powder (purchased in market), 350g/1 Metalaxyl-M seed treatment emulsions (purchased in market), 80% generation, are gloomy
Mancozeb wettable powder (purchased in market), 80% Zineb wettable powder (purchased in market), 20% thiazole zincium suspension agent (purchased in market).
Application Example Sevoflurane bacterium amide and active constituent B and its compounding prevention cucumber downy mildew test of pesticide effectiveness.
This test arrangement investigates cucumber downy mildew disease index before Xianyang, Shanxi province suburban area, medicine, occurs just in disease
Phase dispenser 3 days after dispenser, investigates disease indexes and calculates preventive effect for 10 days, 20 days.Test result is as follows：
14 fluorine ether bacterium amide of table and active constituent B and its compounding prevention cucumber downy mildew test of pesticide effectiveness
As can be seen from Table 14, cucumber downy mildew can be effectively prevented after fluorine ether bacterium amide and active constituent B compoundings, through application
People, which tests, to be found effectively prevent cucumber anthracnose, epidemic disease, scab or sudden after fluorine ether bacterium amide and active constituent B compound
Sick, control effect is above 97%, is better than the preventive effect of single dose, and preventive effect phase is long.To target crop in experiment scope of medication
It has no adverse effects.
Application Example octafluoro ether bacterium amide and active constituent B and its compounding prevention vegetable epidemic disease test of pesticide effectiveness.
This test arrangement investigates vegetable epidemic disease disease index before Xian District, Shanxi Province suburban area, medicine, in the early stages of disease
Dispenser 3 days after dispenser, investigates disease indexes and calculates preventive effect for 10 days, 20 days.Test result is as follows：
15 fluorine ether bacterium amide of table and active constituent B and its compounding prevention vegetable epidemic disease test of pesticide effectiveness
As can be seen from Table 15, vegetable epidemic disease can be effectively prevented after fluorine ether bacterium amide and active constituent B compoundings, through applicant
Experiment finds can also effectively to prevent after fluorine ether bacterium amide is compounded with active constituent B vegetables white blister, Leucoplakia, spot blight, brown
Pinta, Phomopisis vexans, black spot, black rot, balck shank, early blight of eggplant, soft rot, downy mildew or anthracnose, control effect are high
In 97%, it is better than the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects to target crop in experiment scope of medication.
Nine fluorine ether bacterium amide of Application Example and active constituent B and its compounding prevention rice streak test of pesticide effectiveness.
This test arrangement investigates rice streak disease index before Shaanxi Province's Hanzhong City, medicine, applies in the early stages of disease
Medicine 3 days after dispenser, investigates disease indexes and calculates preventive effect for 10 days, 20 days.Test result is as follows：
16 fluorine ether bacterium amide of table and active constituent B and its compounding prevention rice streak test of pesticide effectiveness
As can be seen from Table 16, rice streak can be effectively prevented after fluorine ether bacterium amide and active constituent B compoundings, through application
People, which tests, to be found effectively prevent Achlya spp disease after fluorine ether bacterium amide is compounded with active constituent B, and control effect is above
97%, it is better than the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects to target crop in experiment scope of medication.
Ten fluorine ether bacterium amide of Application Example and active constituent B and its compounding prevention apple peels and cores drug effect examination
It tests.
This test arrangement investigates apple peels and cores disease index before Shaanxi Province's Weinan City Baishui County, medicine, in disease
Evil early period of origination dispenser 3 days after dispenser, investigates disease indexes and calculates preventive effect for 10 days, 20 days.Test result is as follows：
17 fluorine ether bacterium amide of table and active constituent B and its compounding prevention apple peels and cores test of pesticide effectiveness
As can be seen from Table 17, fluorine ether bacterium amide and energy effectively preventing and treating apple-tree spot defoliation after active constituent B compoundings,
Through applicant test find fluorine ether bacterium amide with after active constituent B compounding can also effectively preventing and treating apple-tree brown spot, black rot,
Scab, blossom rot, ring spot, mildew disease, anthracnose, rust, control effect are above 97%, are better than the preventive effect of single dose, and
Preventive effect phase is long.It has no adverse effects to target crop in experiment scope of medication.
Ten monofluoro-ether bacterium amide of Application Example and active constituent B and its compounding prevention citrus anthracnose test of pesticide effectiveness.
This test arrangement investigates citrus anthracnose disease index before Shaanxi Province's Hanzhong City, medicine, applies in the early stages of disease
Medicine 3 days after dispenser, investigates disease indexes and calculates preventive effect for 10 days, 20 days.Test result is as follows：
18 fluorine ether bacterium amide of table and active constituent B and its compounding prevention citrus anthracnose test of pesticide effectiveness
As can be seen from Table 18, citrus anthracnose can be effectively prevented after fluorine ether bacterium amide and active constituent B compoundings, through application
People, which tests, to be found effectively prevent mandarin tree canker after fluorine ether bacterium amide is compounded with active constituent B, and control effect is high
In 97%, it is better than the preventive effect of single dose, and preventive effect phase is long.It has no adverse effects to target crop in experiment scope of medication.
The experiment by different places throughout the country obtains afterwards, fluorine ether bacterium amide with after active constituent B compounding to a variety of
Epidemic disease, anthracnose, downy mildew on crop, spot defoliation, root rot, samping off, seedling rot, brown spot, black rot, black star
Disease, blossom rot, ring spot, mildew disease, rust, white rot, anthrachose of grape, Leucoplakia, spot blight, Phomopisis vexans, black spot, continuous epidemic disease
The preventive effect of the Common Diseases such as disease, soft rot, balck shank, stem wilt, damping-off, canker or cecospora spot is excellent 97% or more
In single dose preventive effect, synergistic effect is apparent.
Claims (6)
1. a kind of composition pesticide of fluorine-containing ether bacterium amide, effective active composition is active components A and active constituent B, feature
It is：Active components A is 1: 80~80: 1 with active constituent B weight ratios, and the active components A is selected from fluorine ether bacterium amide, living
Property ingredient B be zinc thiazole.
2. the composition pesticide of fluorine-containing ether bacterium amide according to claim 1, it is characterised in that：Active components A and activity
The weight ratio of ingredient B is 1: 60~60: 1.
3. the composition pesticide of fluorine-containing ether bacterium amide according to claim 2, it is characterised in that：
The weight ratio of fluorine ether bacterium amide and zinc thiazole is 15: 1~1: 25.
4. the composition pesticide of fluorine-containing ether bacterium amide according to any one of claim 1 to 3, it is characterised in that：Combination
Wettable powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent or microcapsule suspension-is made in object
Suspending agent.
5. the composition pesticide of fluorine-containing ether bacterium amide according to claim 4 is used to prevent the purposes of disease on crops.
6. purposes according to claim 5, it is characterised in that：The disease is epidemic disease, anthracnose, downy mildew, spot
It is defoliation, root rot, samping off, seedling rot, brown spot, black rot, scab, blossom rot, ring spot, mildew disease, rust, white
Maize ear rot, Leucoplakia, spot blight, Phomopisis vexans, black spot, cotton disease, soft rot, balck shank, stem wilt, damping-off, is burst at anthrachose of grape
Ulcer disease or cecospora spot.
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| CN201310415089.3A CN104413019B (en) | 2013-09-02 | 2013-09-02 | A kind of composition pesticide of fluorine-containing ether bacterium amide |
| CN201810577943.9A CN108812673A (en) | 2013-09-02 | 2013-09-02 | A kind of composition pesticide of fluorine-containing ether bacterium amide |
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| CN104957148A (en) * | 2015-06-22 | 2015-10-07 | 广东中迅农科股份有限公司 | Bactericidal composition containing fluxapyroxad and zinc thiozole |
| CN105941438B (en) * | 2016-05-26 | 2018-08-03 | 南京华洲药业有限公司 | A kind of bactericidal composition and its application of fluorine-containing ether bacterium amide and folpet |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102754650A (en) * | 2012-07-24 | 2012-10-31 | 山东省联合农药工业有限公司 | Desflurane bacteria amide compound bactericide |
| CN102792952A (en) * | 2012-09-12 | 2012-11-28 | 山东棉花研究中心 | Bactericide composition for preventing and controlling cotton disease |
| CN102845426A (en) * | 2012-09-19 | 2013-01-02 | 山东省联合农药工业有限公司 | Bactericide combination containing fluorine ether bacteria amide and chlorothalonil |
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| CN102369939A (en) * | 2011-10-28 | 2012-03-14 | 陕西美邦农药有限公司 | Bactericidal combination containing fluopicolide and thiocarbamate compound |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102754650A (en) * | 2012-07-24 | 2012-10-31 | 山东省联合农药工业有限公司 | Desflurane bacteria amide compound bactericide |
| CN102792952A (en) * | 2012-09-12 | 2012-11-28 | 山东棉花研究中心 | Bactericide composition for preventing and controlling cotton disease |
| CN102845426A (en) * | 2012-09-19 | 2013-01-02 | 山东省联合农药工业有限公司 | Bactericide combination containing fluorine ether bacteria amide and chlorothalonil |
Non-Patent Citations (1)
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| 新型杀菌剂氟醚菌酰胺对黄瓜霜霉病的毒力和田间药效评价;张 睿 等;《农药》;20130831;第52卷(第8期);第596-598页 * |
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| CN104413019A (en) | 2015-03-18 |
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| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhang Tong Inventor after: Chen Liping Inventor after: Cao Yan Inventor before: Zhang Tong |
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Effective date of registration: 20191204 Address after: 715500 Pucheng County High-tech Industrial Development Zone, Weinan City, Shaanxi Province Patentee after: SHAANXI MEIBANG PHARMACEUTICAL GROUP Co.,Ltd. Address before: 715500 middle section of North Ring Road, Pucheng County, Shaanxi Patentee before: Zhang Tong |
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