CN103875696B - A kind of bactericidal composition containing amine benzene pyrrole bacterium ketone - Google Patents
A kind of bactericidal composition containing amine benzene pyrrole bacterium ketone Download PDFInfo
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- CN103875696B CN103875696B CN201210566565.7A CN201210566565A CN103875696B CN 103875696 B CN103875696 B CN 103875696B CN 201210566565 A CN201210566565 A CN 201210566565A CN 103875696 B CN103875696 B CN 103875696B
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Abstract
The invention discloses a kind of bactericidal composition containing amine benzene pyrrole bacterium ketone, bactericidal composition containing active components A and active component B, active components A is selected from amine benzene pyrrole bacterium ketone, active component B is selected from any one compound following: thiophanate-methyl, carbendazim, Prochloraz or its salt, fluorine bacterium azoles or Fenamidone, and the weight ratio of active components A and active component B is 1 ︰ 80 ~ 60 ︰ 1.The present composition has greater activity to the multiple diseases in various crop, and has obvious synergistic effect, expands fungicidal spectrum.And have that dosage is little, resistance of rainwater washing against, the obvious feature of synergy.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on corps diseases containing amine benzene pyrrole bacterium ketone.
Background technology
Amine benzene pyrrole bacterium ketone (Fenpyrazamine) is the heterocyclic fungicide based on pyridine.By suppressing the pathogene of the mechanism of action of ergosterol biosynthesis pathway, demonstrate the inhibitory action to mycelial growth and spore germination and pollen tube growth.Mainly prevent and treat gray mold, for grape, cucumber, oranges and tangerines, potato, capsicum, eggplant, ornamental plants etc.
Thiophanate-methyl, carbendazim, Prochloraz or its salt, fluorine bacterium azoles or Fenamidone all belong to common fungicide, are widely used in the disease of crops, and wherein the salt of Prochloraz comprises prochloraz-manganese chloride complex, prochloraz nantokite, prochloraz zinc salt.
But in the real process of agricultural production, the problem that controlling disease the most easily produces is the generation of disease drug resistance.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of sterilization is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of synergy ratio.Study through inventor, find by amine benzene pyrrole bacterium ketone and thiophanate-methyl, carbendazim, Prochloraz or its salt, fluorine bacterium azoles or Fenamidone composite after can produce good synergistic effect, and about amine benzene pyrrole bacterium ketone and the composite relevant report of thiophanate-methyl, carbendazim, Prochloraz or its salt, fluorine bacterium azoles or Fenamidone not yet open.
Summary of the invention
The object of the invention is to propose a kind of to there is the bactericidal composition containing amine benzene pyrrole bacterium ketone that synergistic function, use cost are low, preventive effect is good.
The bactericidal composition containing amine benzene pyrrole bacterium ketone that the present invention proposes contains active components A and active component B, activity is divided into A and active component B weight ratio is 1 ︰ 80 ~ 60 ︰ 1, described active components A is selected from amine benzene pyrrole bacterium ketone, active component B is selected from the one in thiophanate-methyl, carbendazim, Prochloraz or its salt, fluorine bacterium azoles or Fenamidone, and active components A and the preferred weight ratio of active component B are 1 ︰ 60 ~ 40 ︰ 1; The weight ratio being more preferably amine benzene pyrrole bacterium ketone and thiophanate-methyl is 1 ︰ 30 ~ 10 ︰ 1, the weight ratio of amine benzene pyrrole bacterium ketone and carbendazim is 1 ︰ 30 ~ 10 ︰ 1, the weight ratio of amine benzene pyrrole bacterium ketone and Prochloraz or its salt is 1 ︰ 25 ~ 15 ︰ 1, the weight ratio of amine benzene pyrrole bacterium ketone and fluorine bacterium azoles is 1 ︰ 20 ~ 20 ︰ 1, and the weight ratio of amine benzene pyrrole bacterium ketone and Fenamidone is 1 ︰ 20 ~ 20 ︰ 1; The weight ratio most preferably being amine benzene pyrrole bacterium ketone and thiophanate-methyl is 1 ︰ 19 ~ 1 ︰ 1, the weight ratio of amine benzene pyrrole bacterium ketone and carbendazim is 1 ︰ 19 ~ 1 ︰ 1, the weight ratio of amine benzene pyrrole bacterium ketone and Prochloraz or its salt is 1 ︰ 14 ~ 4 ︰ 1, the weight ratio of amine benzene pyrrole bacterium ketone and fluorine bacterium azoles is 1 ︰ 9 ~ 9 ︰ 1, and the weight ratio of amine benzene pyrrole bacterium ketone and Fenamidone is 1 ︰ 9 ~ 9 ︰ 1.
The bactericidal composition containing amine benzene pyrrole bacterium ketone that the present invention proposes is for preventing and treating the purposes of disease on crops, and described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop.
It is sick that described disease comprises leaf mold, leaf rot, green mould, penicilliosis, powdery mildew, smut, brown spot, leaf spot, scab, ring rot, fusarium wilt, rot, ring spot, zonate spot, rice blast, banded sclerotial blight, head blight, stalk break, downy mildew, root rot, anthracnose, seedling laying disease, epidemic disease, spot defoliation, leaf blight, band maize ear rot, black rot, gray mold, anthrachose of grape, false smut, bakanae disease, crown rot, rust, damping off or mottled rot.
The weight ratio of active components A, active component B is 1 ︰ 80 ~ 60 ︰ 1.In usual composition, the weight percentage of active component is 0.5% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains the active substance of by weight 1% ~ 70%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Bactericidal composition of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by common processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active substance, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer, disintegrant, antifreeze etc.
Bactericidal composition of the present invention, can be processed into acceptable formulation in any sterilization on demand, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
Composition comprises following constituent content when making wetting powder: active components A 1% ~ 60%, active component B1% ~ 80%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
Composition comprises following constituent content when making water dispersible granules: active components A 1% ~ 60%, active component B1% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following constituent content when making suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making suspension emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 1% ~ 15%, thickener 0 ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Composition comprises following constituent content when making microemulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 3% ~ 25%, antifreeze 0 ~ 8%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Composition comprises following constituent content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifier 1% ~ 7%, defoamer 0.01% ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Composition comprises following constituent content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%;
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) amine benzene pyrrole bacterium ketone and thiophanate-methyl, carbendazim, Prochloraz or its salt, fluorine bacterium azoles or Fenamidone composite after, there is obvious synergy and lasting effect; (2) all greater activity is had to the disease on cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop; (3) decrease pesticide usage amount, reduce the residual quantity of agricultural chemicals on crop, alleviate environmental pollution; (4) to person poultry safety, Environmental compatibility is good; And preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Embodiment 1 ~ 16 wetting powder
Amine benzene pyrrole bacterium ketone, active component B, dispersant, wetting agent, filler are mixed in mixed cylinder, mixes again after airslide disintegrating mill is pulverized, wetting powder product of the present invention can be obtained, specifically in table 1.
The each component of table 1 embodiment 1 ~ 16 and weight portion
Embodiment 17 ~ 32 water dispersible granules
Amine benzene pyrrole bacterium ketone, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, water dispersible granules product of the present invention can being obtained, specifically in table 2.
The each component of table 2 embodiment 17 ~ 32 and weight portion
By thiophanate-methyl, cyazofamid, fluorine bacterium azoles, Fenamidone, carbendazim, Prochloraz or its salt interchange in table 1,2, novel formulation can be obtained.
Embodiment 33 ~ 48 suspending agent
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), mix through high speed shear, add amine benzene pyrrole bacterium ketone, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can obtain suspending agent product of the present invention, specifically in table 3.
The each component of table 3 embodiment 33 ~ 48 and weight portion
Embodiment 49 ~ 56 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add amine benzene pyrrole bacterium ketone, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained amine benzene pyrrole bacterium ketone suspending agent, then by active component B, solvent, emulsifier and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, surplus deionized water is supplied, obtained suspension emulsion product of the present invention, specifically in table 4.The each component of table 4 embodiment 49 ~ 56 and weight portion
Embodiment 57 ~ 64 aqueous emulsion
Amine benzene pyrrole bacterium ketone, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, surplus deionized water is supplied; Aqueous emulsion product of the present invention can be obtained, specifically in table 5.
The each component of table 5 embodiment 57 ~ 64 and weight portion
Thiophanate-methyl, carbendazim, Prochloraz or its salt, fluorine bacterium azoles or Fenamidone in table 3 ~ 6 are exchanged, can novel formulation be obtained.
Embodiment 65 ~ 67 microemulsion
Amine benzene pyrrole bacterium ketone, active component B, solvent, emulsifier, antifreeze (can add and can not add), defoamer are fully mixed into the oil phase of homogeneous transparent, under agitation slowly add deionized water, form WO emulsion, again through agitating heating, make it rapid phase inversion and become oil-in-water type, be chilled to room temperature to make it to reach balance, after filtration, surplus deionized water is supplied; Microemulsion product of the present invention can be obtained, specifically in table 6.
The each component of table 6 embodiment 65 ~ 67 and weight portion
Embodiment 68,69 microcapsule suspending agent
By amine benzene pyrrole bacterium ketone, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 7.
Table 7 embodiment 68,69 each component and weight portion
Embodiment 70,71 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add amine benzene pyrrole bacterium ketone, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, make the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition, specifically in table 8.
Table 8 embodiment 70,71 each component and weight portion
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First by Toxicity Determination, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carries out field trial.
Test method: determine that after the effective inhibition concentration scope of each medicament, medicament establishes 5 dosage process respectively by active constituent content through prerun, if clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure medicament to the virulence of crop germ.Measure colony diameter by right-angled intersection method after 72h, calculate each process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value to (x), tries to achieve virulence regression equation (y=a+bx), and calculate the EC of often kind of medicament thus with method of least squares
50value.Calculate two medicament different ratio synergies ratio (SR) according to Wadley method, SR < 0.5 is antagonism, and 0.5≤SR≤1.5 are summation action simultaneously, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active components A and the ratio of active component B shared by combination;
A is amine benzene pyrrole bacterium ketone;
B is selected from the one in thiophanate-methyl, carbendazim, Prochloraz or its salt, fluorine bacterium azoles or Fenamidone.
Virulence experiment part: test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Application Example two:
For examination disease: graw mold of tomato;
Experimental scheme: through effective inhibition concentration scope of both preliminary experiment determination amine benzene pyrrole bacterium ketone and thiophanate-methyl different ratio mixture.
Toxicity test result
Table 9 amine benzene pyrrole bacterium ketone and the composite toxicity test analysis of results table to graw mold of tomato of thiophanate-methyl
As shown in Table 9, the proportioning of amine benzene pyrrole bacterium ketone and the composite control graw mold of tomato of thiophanate-methyl is when 1:80 ~ 60:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, the proportioning of amine benzene pyrrole bacterium ketone and thiophanate-methyl is in 1:30 ~ 10: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.85, when amine benzene pyrrole bacterium ketone and thiophanate-methyl weight ratio are 1:9, synergy ratio is maximum, and synergistic effect is the most obvious.Discovery is tested through applicant, the proportioning of amine benzene pyrrole bacterium ketone and thiophanate-methyl is 1:30, 1:29, 1:28, 1:27, 1:26, 1:25, 1:24, 1:23, 1:22, 1:21, 1:20, 1:19, 1:18, 1:17, 1:16, 1:15, 1:14, 1:13, 1:12, 1:11, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, to leaf mold during 10:1, leaf rot, green mould, penicilliosis, powdery mildew, smut, brown spot, leaf spot, scab, ring rot, fusarium wilt, rot, ring spot, zonate spot, rice blast, banded sclerotial blight, head blight, stalk break, downy mildew, root rot, anthracnose, seedling laying is sick, epidemic disease, spot defoliation, leaf blight, band maize ear rot, black rot, gray mold, anthrachose of grape, false smut, bakanae disease, crown rot, rust, the control of damping off or mottled rot disease has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example three:
For examination disease: grape grey mould;
Experimental scheme: through effective inhibition concentration scope of both preliminary experiment determination amine benzene pyrrole bacterium ketone and carbendazim different ratio mixture.
Toxicity test result
Table 10 amine benzene pyrrole bacterium ketone and the composite toxicity test analysis of results table to grape grey mould of carbendazim
As shown in Table 10, the proportioning of amine benzene pyrrole bacterium ketone and the composite control grape grey mould of carbendazim is when 1:80 ~ 60:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, the proportioning of amine benzene pyrrole bacterium ketone and carbendazim is in 1:30 ~ 10: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.85, when amine benzene pyrrole bacterium ketone and carbendazim weight ratio are 1:10, synergy ratio is maximum, and synergistic effect is the most obvious.Discovery is tested through applicant, the proportioning of amine benzene pyrrole bacterium ketone and carbendazim is 1:30, 1:29, 1:28, 1:27, 1:26, 1:25, 1:24, 1:23, 1:22, 1:21, 1:20, 1:19, 1:18, 1:17, 1:16, 1:15, 1:14, 1:13, 1:12, 1:11, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, to leaf mold during 10:1, leaf rot, green mould, penicilliosis, powdery mildew, smut, brown spot, leaf spot, scab, ring rot, fusarium wilt, rot, ring spot, zonate spot, rice blast, banded sclerotial blight, head blight, stalk break, downy mildew, root rot, anthracnose, seedling laying is sick, epidemic disease, spot defoliation, leaf blight, band maize ear rot, black rot, gray mold, anthrachose of grape, false smut, bakanae disease, crown rot, rust, the control of damping off or mottled rot disease has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example four:
For examination disease: bakanae disease of rice;
Experimental scheme: through effective inhibition concentration scope of preliminary experiment determination amine benzene pyrrole bacterium ketone and Prochloraz or its both salt different ratio mixture.
Toxicity test result
Table 11 amine benzene pyrrole bacterium ketone and Prochloraz or the composite toxicity test analysis of results table to bakanae disease of rice of its salt
As shown in Table 11, the proportioning of amine benzene pyrrole bacterium ketone and Prochloraz or the composite water prevention rice bakanae disease of its salt is when 1:80 ~ 60:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, the proportioning of amine benzene pyrrole bacterium ketone and Prochloraz or its salt is in 1:25 ~ 15: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.85, when amine benzene pyrrole bacterium ketone and Prochloraz or its salt weight ratio are 1:5, synergy ratio is maximum, and synergistic effect is the most obvious.Discovery is tested through applicant, the proportioning of amine benzene pyrrole bacterium ketone and Prochloraz or its salt is 1:25, 1:24, 1:23, 1:22, 1:21, 1:20, 1:19, 1:18, 1:17, 1:16, 1:15, 1:14, 1:13, 1:12, 1:11, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 11:1, 12:1, 13:1, 14:1, to leaf mold during 15:1, leaf rot, green mould, penicilliosis, powdery mildew, smut, brown spot, leaf spot, scab, ring rot, fusarium wilt, rot, ring spot, zonate spot, rice blast, banded sclerotial blight, head blight, stalk break, downy mildew, root rot, anthracnose, seedling laying is sick, epidemic disease, spot defoliation, leaf blight, band maize ear rot, black rot, gray mold, anthrachose of grape, false smut, bakanae disease, crown rot, rust, the control of damping off or mottled rot disease has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example five:
For examination disease: pear scab;
Experimental scheme: through effective inhibition concentration scope of both preliminary experiment determination amine benzene pyrrole bacterium ketone and fluorine bacterium azoles different ratio mixture.
Toxicity test result
Table 12 amine benzene pyrrole bacterium ketone and the composite toxicity test analysis of results table to pear scab of fluorine bacterium azoles
As shown in Table 12, the proportioning of amine benzene pyrrole bacterium ketone and the composite control pear scab of fluorine bacterium azoles is when 1:80 ~ 60:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, the proportioning of amine benzene pyrrole bacterium ketone and fluorine bacterium azoles is in 1:20 ~ 20: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.85, when amine benzene pyrrole bacterium ketone and fluorine bacterium azoles weight ratio are 1:1, synergy ratio is maximum, and synergistic effect is the most obvious.Discovery is tested through applicant, the proportioning of amine benzene pyrrole bacterium ketone and fluorine bacterium azoles is 1:20, 1:19, 1:18, 1:17, 1:16, 1:15, 1:14, 1:13, 1:12, 1:11, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 11:1, 12:1, 13:1, 14:1, 15:1, 16:1, 17:1, 18:1, 19:1, to leaf mold during 20:1, leaf rot, green mould, penicilliosis, powdery mildew, smut, brown spot, leaf spot, scab, ring rot, fusarium wilt, rot, ring spot, zonate spot, rice blast, banded sclerotial blight, head blight, stalk break, downy mildew, root rot, anthracnose, seedling laying is sick, epidemic disease, spot defoliation, leaf blight, band maize ear rot, black rot, gray mold, anthrachose of grape, false smut, bakanae disease, crown rot, rust, the control of damping off or mottled rot disease has obvious synergistic effect, synergy ratio is all more than 1.5.
Application Example six:
For examination disease: downy mildew of garpe;
Experimental scheme: through effective inhibition concentration scope of both preliminary experiment determination amine benzene pyrrole bacterium ketone and Fenamidone different ratio mixture.
Toxicity test result
Table 13 amine benzene pyrrole bacterium ketone and the composite toxicity test analysis of results table to downy mildew of garpe of Fenamidone
As shown in Table 13, amine benzene pyrrole bacterium ketone and the composite proportioning of preventing and treating downy mildew of garpe of Fenamidone are when 1:80 ~ 60:1, synergy ratio SR is all greater than 1.5, both explanations mixture within the scope of 1:80 ~ 60:1 all shows synergistic effect, the proportioning of amine benzene pyrrole bacterium ketone and Fenamidone is in 1:20 ~ 20: 1, and synergistic effect is more outstanding, and synergy ratio is all greater than 2.85, when amine benzene pyrrole bacterium ketone and Fenamidone weight ratio are 1:2, synergy ratio is maximum, and synergistic effect is the most obvious.Discovery is tested through applicant, the proportioning of amine benzene pyrrole bacterium ketone and Fenamidone is 1:20, 1:19, 1:18, 1:17, 1:16, 1:15, 1:14, 1:13, 1:12, 1:11, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 1:4, 1:3, 1:2, 1:1, 2:1, 3:1, 4:1, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 11:1, 12:1, 13:1, 14:1, 15:1, 16:1, 17:1, 18:1, 19:1, to leaf mold during 20:1, leaf rot, green mould, penicilliosis, powdery mildew, smut, brown spot, leaf spot, scab, ring rot, fusarium wilt, rot, ring spot, zonate spot, rice blast, banded sclerotial blight, head blight, stalk break, downy mildew, root rot, anthracnose, seedling laying is sick, epidemic disease, spot defoliation, leaf blight, band maize ear rot, black rot, gray mold, anthrachose of grape, false smut, bakanae disease, crown rot, rust, the control of damping off or mottled rot disease has obvious synergistic effect, synergy ratio is all more than 1.5.
Effect experiment part: test medicine is researched and developed by Shanxi Thompson Biological Technology Co., Ltd., provided, contrast medicament 30% amine benzene pyrrole bacterium ketone suspending agent (autogamy), 70% thiophanate-methyl wetting powder (commercial), 25% carbendazol wettable powder (commercial), 25% Prochloraz missible oil (commercial), 30% triflumizole wettable powder (commercial), 50% Fenamidone suspending agent (autogamy).The investigation state of an illness before medicine, in the first time dispenser of state of an illness initial stage, altogether dispenser 1 time.
Application Example seven amine benzene pyrrole bacterium ketone and active component B and compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation powdery mildew of cucumber disease index before medicine, in the dispenser of disease initial stage of origination, 3 days, 10 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 14 amine benzene pyrrole bacterium ketone and active component B and compositely prevent and treat the powdery mildew of cucumber test of pesticide effectiveness
As can be seen from Table 14, amine benzene pyrrole bacterium ketone and active component B composite after effectively can prevent and treat powdery mildew of cucumber, through applicant test find amine benzene pyrrole bacterium ketone and active component B composite after also can effectively prevent and treat cucumber downy mildew, cucumber anthracnose and gray mold of cucumber, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example eight amine benzene pyrrole bacterium ketone and active component B and the composite control graw mold of tomato test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation graw mold of tomato disease index before medicine, in the dispenser of disease initial stage of origination, 3 days, 10 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 15 amine benzene pyrrole bacterium ketone and active component B and the composite control graw mold of tomato test of pesticide effectiveness thereof
As can be seen from Table 15, amine benzene pyrrole bacterium ketone and active component B composite after effectively can prevent and treat graw mold of tomato, through applicant test find amine benzene pyrrole bacterium ketone and active component B composite after also can effectively prevent and treat tomato downy mildew or tomato blight, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine amine benzene pyrrole bacterium ketone and active component B and the composite control rice blast test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and investigation rice blast disease index before medicine, in the dispenser of disease initial stage of origination, 7 days, 14 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 16 amine benzene pyrrole bacterium ketone and active component B and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 16, amine benzene pyrrole bacterium ketone and active component B composite after effectively can prevent and treat rice blast, through applicant test find amine benzene pyrrole bacterium ketone and active component B composite after also can preventing and controlling green smut of rice, bakanae disease of rice or rice sheath blight disease, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten amine benzene pyrrole bacterium ketone and active component B and the composite control pear scab test of pesticide effectiveness thereof
This test arrangement is in Weinan City Dali County, Shaanxi Province, and investigation pear scab disease index before medicine, in the dispenser of disease initial stage of origination, 7 days, 14 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 17 amine benzene pyrrole bacterium ketone and active component B and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 17, amine benzene pyrrole bacterium ketone and active component B composite after effectively can prevent and treat pear scab, through applicant test find amine benzene pyrrole bacterium ketone and active component B composite after also effectively can prevent and treat pear tree powdery mildew, pear tree rust or pear tree ring spot, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example undecylamine benzene pyrrole bacterium ketone and active component B and the composite control citrus anthracnose test of pesticide effectiveness thereof
This test arrangement is at Shaanxi Province's Hanzhong City, and investigation citrus anthracnose disease index before medicine, in the dispenser of disease initial stage of origination, 7 days, 15 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 18 amine benzene pyrrole bacterium ketone and active component B and the composite control citrus anthracnose test of pesticide effectiveness thereof
As can be seen from Table 18, amine benzene pyrrole bacterium ketone and active component B composite after effectively can prevent and treat citrus anthracnose, through applicant test find amine benzene pyrrole bacterium ketone and active component B composite after also effectively can prevent and treat oranges and tangerines band maize ear rot, green rot or black rot, control efficiency is all higher than 96%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example lauryl amine benzene pyrrole bacterium ketone and active component B and the composite control grape grey mould test of pesticide effectiveness thereof
This test arrangement is in Weinan City Dali County, Shaanxi Province, and investigation grape grey mould disease index before medicine, in the dispenser of disease initial stage of origination, 7 days, 15 days, 30 days investigation disease indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 19 amine benzene pyrrole bacterium ketone and active component B and the composite control grape grey mould test of pesticide effectiveness thereof
As can be seen from Table 19, amine benzene pyrrole bacterium ketone and active component B composite after effectively can prevent and treat grape grey mould, through applicant test find amine benzene pyrrole bacterium ketone and active component B composite after also can effectively prevent and treat anthracnose of grape or downy mildew of garpe, control efficiency is all higher than 95%, be better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, amine benzene pyrrole bacterium ketone and thiophanate-methyl, carbendazim, Prochloraz or its salt, fluorine bacterium azoles or Fenamidone composite rear to the leaf mold in various crop, leaf rot, green mould, penicilliosis, powdery mildew, smut, brown spot, leaf spot, scab, ring rot, fusarium wilt, rot, ring spot, zonate spot, rice blast, banded sclerotial blight, head blight, stalk break, downy mildew, root rot, anthracnose, seedling laying is sick, epidemic disease, spot defoliation, leaf blight, band maize ear rot, black rot, gray mold, anthrachose of grape, false smut, bakanae disease, crown rot, rust, the preventive effect of the Common Diseases such as damping off or mottled rot disease is all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. the bactericidal composition containing amine benzene pyrrole bacterium ketone, effective active composition is active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1 ︰ 80 ~ 60 ︰ 1, described active components A is amine benzene pyrrole bacterium ketone, and active component B is Prochloraz or its salt.
2. the bactericidal composition containing amine benzene pyrrole bacterium ketone according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 60 ~ 40 ︰ 1.
3. the bactericidal composition containing amine benzene pyrrole bacterium ketone according to claim 2, is characterized in that: the weight ratio of amine benzene pyrrole bacterium ketone and Prochloraz or its salt is 1 ︰ 25 ~ 15 ︰ 1.
4. the bactericidal composition containing amine benzene pyrrole bacterium ketone according to any one of claim 1 to 3, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent or microcapsule suspension-suspendinagent agent.
5. the bactericidal composition containing amine benzene pyrrole bacterium ketone according to claim 4 is for preventing and treating the purposes of disease on crops.
6. purposes according to claim 5, is characterized in that: described disease is that leaf mold, leaf rot, green mould, penicilliosis, powdery mildew, smut, brown spot, leaf spot, scab, ring rot, fusarium wilt, rot, ring spot, zonate spot, rice blast, banded sclerotial blight, head blight, stalk break, downy mildew, root rot, anthracnose, seedling laying disease, epidemic disease, spot defoliation, leaf blight, band maize ear rot, black rot, gray mold, anthrachose of grape, false smut, bakanae disease, crown rot, rust, damping off or mottled rot are sick.
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| CN201510427164.7A CN104996445A (en) | 2012-12-24 | 2012-12-24 | Fenpyrazamine-containing sterilization composition |
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| CN107467051A (en) * | 2017-07-05 | 2017-12-15 | 南京红太阳股份有限公司 | A kind of bactericidal composition and its application of the pyrrole bacterium ketone of benzene containing amine and penconazole |
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| US8748339B2 (en) * | 2008-06-05 | 2014-06-10 | Basf Se | Synergistic fungicidal mixtures |
| EP2467367B1 (en) * | 2009-08-20 | 2014-04-09 | Bayer CropScience AG | 3-triazolylphenyl-substituted sulphide derivatives as acaricides and insecticides |
| US20130317067A1 (en) * | 2010-12-09 | 2013-11-28 | Bayer Intellectual Property Gmbh | Pesticidal mixtures with improved properties |
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